TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T79326 Ketohexokinase B25WCX 4-[3-Methylsulfanyl-6-(piperazin-1-ylmethyl)indazol-1-yl]aniline Investigative 86767136 C19H23N5S 353.5 CSC1=NN(C2=C1C=CC(=C2)CN3CCNCC3)C4=CC=C(C=C4)N IC50 ~ 51000 nM Poor binder T79326 Ketohexokinase BDA8H1 [3-Methylsulfanyl-1-(4-nitrophenyl)indazol-6-yl]-piperazin-1-ylmethanone Investigative 67453804 C19H19N5O3S 397.5 CSC1=NN(C2=C1C=CC(=C2)C(=O)N3CCNCC3)C4=CC=C(C=C4)[N+](=O)[O-] IC50 ~ 51000 nM Poor binder T79326 Ketohexokinase BIE2R3 [(3r)-1-(5-Methyl-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)piperidin-3-Yl]methanol Investigative 129900195 C13H18N4O 246.31 CC1=CNC2=C1C(=NC=N2)N3CCC[C@H](C3)CO IC50 = 118000 nM Poor binder T79326 Ketohexokinase BLB69Y 3-(Trifluoromethyl)quinoxalin-2-ol Investigative 611792 C9H5F3N2O 214.14 C1=CC=C2C(=C1)NC(=O)C(=N2)C(F)(F)F IC50 = 100000 nM Poor binder