TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	B5WY7L	4-[2-(2-Amino-6-oxo-1,6-dihydro-9H-purine-8-ylthio)acetyl]benzonitrile	Investigative	136610106	C14H10N6O2S	326.34	C1=CC(=CC=C1C#N)C(=O)CSC2=NC3=C(N2)C(=O)NC(=N3)N	IC50 = 88000 nM	Poor binder
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	B7WH1J	2-Amino-8-{[2-(4-Methylphenyl)-2-Oxoethyl]sulfanyl}-1,7-Dihydro-6h-Purin-6-One	Investigative	135548073	C14H13N5O2S	315.35	CC1=CC=C(C=C1)C(=O)CSC2=NC3=C(N2)C(=O)NC(=N3)N	IC50 = 64000 nM	Poor binder
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	BBO83T	2-Amino-8-{[2-(3-Methylphenyl)-2-Oxoethyl]sulfanyl}-1,9-Dihydro-6h-Purin-6-One	Investigative	135566867	C14H13N5O2S	315.35	CC1=CC(=CC=C1)C(=O)CSC2=NC3=C(N2)C(=O)NC(=N3)N	IC50 = 51000 nM	Poor binder
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	BE8S2I	5'-S-[1-(2-{[(2-Amino-4-Oxo-3,4-Dihydropteridin-6-Yl)methyl]amino}ethyl)piperidin-4-Yl]-5'-Thioadenosine	Investigative	135566603	C24H32N12O4S	584.7	C1CN(CCC1SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)CCNCC5=CN=C6C(=N5)C(=O)NC(=N6)N	IC50 ~ 100000 nM	Poor binder
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	BFE7G9	2-Amino-8-[2-(4-fluorophenyl)-2-oxoethylthio]-9H-purine-6(1H)-one	Investigative	135526727	C13H10FN5O2S	319.32	C1=CC(=CC=C1C(=O)CSC2=NC3=C(N2)C(=O)NC(=N3)N)F	IC50 = 79000 nM	Poor binder
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	BHY2J9	2-Amino-8-[2-(4-hydroxyphenyl)-2-oxoethylthio]-9H-purine-6(1H)-one	Investigative	136610105	C13H11N5O3S	317.33	C1=CC(=CC=C1C(=O)CSC2=NC3=C(N2)C(=O)NC(=N3)N)O	IC50 = 82000 nM	Poor binder
T79724	Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase	BU1S4F	2-Amino-8-[(2-Oxo-2-Phenylethyl)sulfanyl]-1,9-Dihydro-6h-Purin-6-One	Investigative	135526726	C13H11N5O2S	301.33	C1=CC=C(C=C1)C(=O)CSC2=NC3=C(N2)C(=O)NC(=N3)N	IC50 = 139000 nM	Poor binder