TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T80942	Matrix metalloproteinase 12	D00HNB	Clodronate	Approved	25419	CH4Cl2O6P2	244.89	C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl	IC50 = 121000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D00HNB	Clodronate	Approved	25419	CH4Cl2O6P2	244.89	C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl	IC50 = 145000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D0Q8CS	Tiludronic acid	Approved	60937	C7H9ClO6P2S	318.61	C1=CC(=CC=C1SC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D0VM2L	Zoledronate	Approved	68740	C5H10N2O7P2	272.09	C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 14	D0G1LL	1607004-34-1	Patented	74221072	C20H22F3N3O3	409.4	C1CC1[C@H](CC2=CC=C(C=C2)C(F)(F)F)C(=O)NC[C@@]3(C(=O)NC(=O)N3)C4CC4	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D0G1LL	1607004-34-1	Patented	74221072	C20H22F3N3O3	409.4	C1CC1[C@H](CC2=CC=C(C=C2)C(F)(F)F)C(=O)NC[C@@]3(C(=O)NC(=O)N3)C4CC4	IC50 = 99710 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0G1LL	1607004-34-1	Patented	74221072	C20H22F3N3O3	409.4	C1CC1[C@H](CC2=CC=C(C=C2)C(F)(F)F)C(=O)NC[C@@]3(C(=O)NC(=O)N3)C4CC4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D0G1LL	1607004-34-1	Patented	74221072	C20H22F3N3O3	409.4	C1CC1[C@H](CC2=CC=C(C=C2)C(F)(F)F)C(=O)NC[C@@]3(C(=O)NC(=O)N3)C4CC4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 = 56800 nM	Poor binder
T80942	Matrix metalloproteinase 13	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0UM5R	US9206139, 5	Patented	74221070	C19H22F3N3O3	397.4	CC(C)(CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B01CEJ	(1R,2S)-1-({3-Fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)-2-N-hydroxycyclopropane-1,2-dicarboxamide	Investigative	25138228	C28H24FN3O4	485.5	C1[C@@H]([C@@]1(CC2=CC(=C(C=C2)OCC3=CC(=NC4=CC=CC=C43)C5=CC=CC=C5)F)C(=O)N)C(=O)NO	Ki = 128000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B01JWL	N-((S)-2-Benzyloxy-1-dimethylcarbamoyl-propyl)-N''-hydroxy-oxalamide	Investigative	44384146	C15H21N3O5	323.34	CC([C@@H](C(=O)N(C)C)NC(=O)C(=O)NO)OCC1=CC=CC=C1	Ki = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B02AMR	(5S)-5-Methyl-5-[[4-[5-[(3-methyl-1,2-oxazol-5-yl)methoxy]pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]imidazolidine-2,4-dione	Investigative	73352170	C18H23N7O6S	465.5	CC1=NOC(=C1)COC2=CN=C(N=C2)N3CCN(CC3)S(=O)(=O)C[C@@]4(C(=O)NC(=O)N4)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B03XNO	(4S)-5-[3-(Carboxymethyl)piperidin-1-yl]-5-oxo-4-[3-(4-thiophen-2-ylphenyl)propanoylamino]pentanoic acid	Investigative	50991513	C25H30N2O6S	486.6	C1CC(CN(C1)C(=O)[C@H](CCC(=O)O)NC(=O)CCC2=CC=C(C=C2)C3=CC=CS3)CC(=O)O	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B05XVW	2-Cinnamamido-N1-hydroxy-N4-propylsuccinamide	Investigative	46228248	C16H21N3O4	319.36	CCCNC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 131000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B07UOM	N-Hydroxy-N-[2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-1-(2,2,5-trimethyl-[1,3]dioxolan-4-yl)-ethyl]-formamide	Investigative	44314366	C22H24F3NO8S	519.5	C[C@H]1C(OC(O1)(C)C)[C@@H](CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B08OYM	(2S)-N-Hydroxy-1-(4-phenylphenyl)sulfonylpyrrolidine-2-carboxamide	Investigative	57391413	C17H18N2O4S	346.4	C1C[C@H](N(C1)S(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3)C(=O)NO	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B09XSF	Hydroxamate deriv., 78	Investigative	24799779	C23H23N3O4	405.4	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)C[C@@]4(C[C@@H]4C(=O)NO)C(=O)N	Ki = 58000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B09XSF	Hydroxamate deriv., 78	Investigative	24799779	C23H23N3O4	405.4	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)C[C@@]4(C[C@@H]4C(=O)NO)C(=O)N	Ki = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B0BI8G	N-Methyl-4-(4-methylphenoxy)-N-(pyridin-4-ylmethyl)benzamide	Investigative	56676871	C21H20N2O2	332.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)N(C)CC3=CC=NC=C3	IC50 = 50118.72 nM	Poor binder
T80942	Matrix metalloproteinase 14	B0BMJ6	Benzyl N-[(4R)-4-[[4-(4-cyano-2-methylphenyl)piperazin-1-yl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate	Investigative	127026888	C25H32N6O6S	544.6	CC1=C(C=CC(=C1)C#N)N2CCN(CC2)S(=O)(=O)N[C@H](CCCNC(=O)OCC3=CC=CC=C3)C(=O)NO	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0CFK6	Thioacetic acid S-[(4S,5S)-2-(4-chloro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester	Investigative	44394754	C13H12ClNO2S	281.76	CC(=O)S[C@H]1[C@@H](OC(=N1)C2=CC=C(C=C2)Cl)C=C	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B0D5MH	3-[({2-[4-({[(4s)-4-Methyl-2,5-Dioxoimidazolidin-4-Yl]methyl}sulfonyl)piperazin-1-Yl]pyrimidin-5-Yl}oxy)methyl]benzonitrile	Investigative	71815036	C21H23N7O5S	485.5	C[C@]1(C(=O)NC(=O)N1)CS(=O)(=O)N2CCN(CC2)C3=NC=C(C=N3)OCC4=CC(=CC=C4)C#N	IC50 = 53584 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0DQ4U	(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-phenylpentanamide	Investigative	44356805	C24H32N4O3	424.5	C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)NC2=CC=CC=C2)N	IC50 = 52100 nM	Poor binder
T80942	Matrix metalloproteinase 3	B0DQ4U	(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-phenylpentanamide	Investigative	44356805	C24H32N4O3	424.5	C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)NC2=CC=CC=C2)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0G6CN	(2R)-2-[(4-But-2-ynoxyphenyl)sulfonylamino]-3-[1-[(4-methoxyphenyl)methyl]indol-3-yl]propanoic acid	Investigative	11599024	C29H28N2O6S	532.6	CC#CCOC1=CC=C(C=C1)S(=O)(=O)N[C@H](CC2=CN(C3=CC=CC=C32)CC4=CC=C(C=C4)OC)C(=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B0GHZ3	(2S)-4-Fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]butanoic acid	Investigative	70941091	C17H19FN2O5S	382.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CCF)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B0GWI6	2-[(4-Methoxyphenyl)methylthio]-6-methyl-1H-pyrimidin-4-one	Investigative	135438809	C13H14N2O2S	262.33	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B0GWI6	2-[(4-Methoxyphenyl)methylthio]-6-methyl-1H-pyrimidin-4-one	Investigative	135438809	C13H14N2O2S	262.33	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0H7LV	2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2-hydroxy-indan-1-yl)-succinamide	Investigative	15524390	C21H22N2O6	398.4	C1[C@H]([C@H](C2=CC=CC=C21)NC(=O)[C@H](CC3=CC4=C(C=C3)OCO4)CC(=O)NO)O	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B0HJ9Y	[Phosphono-[4-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204931	C8H10F3NO6P2	335.11	C1=CC(=CC=C1C(F)(F)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B0HJ9Y	[Phosphono-[4-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204931	C8H10F3NO6P2	335.11	C1=CC(=CC=C1C(F)(F)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B0HJ9Y	[Phosphono-[4-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204931	C8H10F3NO6P2	335.11	C1=CC(=CC=C1C(F)(F)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B0HYB2	N-(Cyclohexylmethyl)-4-(4-methylphenoxy)benzamide	Investigative	56666624	C21H25NO2	323.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3CCCCC3	IC50 = 50118.72 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0I7JH	2-Cinnamamido-4-(dodecylamino)-4-oxobutanoic acid	Investigative	46228246	C25H38N2O4	430.6	CCCCCCCCCCCCNC(=O)C[C@H](C(=O)O)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 176500 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0I9FV	(R)-5-(4-Bromo-2-fluorobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582586	C22H24BrFN2O7	527.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NCC2=C(C=C(C=C2)Br)F	IC50 = 76100 nM	Poor binder
T80942	Matrix metalloproteinase 3	B0IWY1	Isoacteoside	Investigative	6476333	C29H36O15	624.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2[C@@H]([C@H](O[C@H]([C@@H]2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)/C=C/C4=CC(=C(C=C4)O)O)O)O)O)O	IC50 = 91410 nM	Poor binder
T80942	Matrix metalloproteinase 3	B0J4RS	(R)-2-(N-Isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid	Investigative	45482676	C20H25NO5S	391.5	CC(C)[C@H](C(=O)O)N(OC(C)C)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2	IC50 = 54000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0J4RS	(R)-2-(N-Isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid	Investigative	45482676	C20H25NO5S	391.5	CC(C)[C@H](C(=O)O)N(OC(C)C)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B0MS1B	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-pyran-4-ylidenemethyl)-ethyl]-formamide	Investigative	23017979	C26H28N2O6S	496.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCOCC4)N(C=O)O	IC50 = 53000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0MS1B	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-pyran-4-ylidenemethyl)-ethyl]-formamide	Investigative	23017979	C26H28N2O6S	496.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCOCC4)N(C=O)O	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B0MUP5	2-(4-Chlorophenoxy)-N-{[(4r)-4-Methyl-2,5-Dioxoimidazolidin-4-Yl]methyl}acetamide	Investigative	86287514	C13H14ClN3O4	311.72	C[C@]1(C(=O)NC(=O)N1)CNC(=O)COC2=CC=C(C=C2)Cl	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B0MUP5	2-(4-Chlorophenoxy)-N-{[(4r)-4-Methyl-2,5-Dioxoimidazolidin-4-Yl]methyl}acetamide	Investigative	86287514	C13H14ClN3O4	311.72	C[C@]1(C(=O)NC(=O)N1)CNC(=O)COC2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B0N7VD	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-chlorophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036770	C17H10ClN3OS2	371.9	C1=CC=C(C(=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)Cl	IC50 = 89430 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0PJ6F	(S)-N,N-Diethyl-2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenyl-propanamide	Investigative	46232491	C24H28N4O3	420.5	CCN(CC)C(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN2C3=CC=CC=C3N=C(C2=O)C	IC50 = 105300 nM	Poor binder
T80942	Matrix metalloproteinase 3	B0QR5V	3-(Hydroxymethyl)-6-(4-hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethynyl]benzoic acid	Investigative	122179777	C22H16O5	360.4	C1=CC(=CC=C1C#CC2=C(C=CC(=C2C(=O)O)C3=CC=C(C=C3)O)CO)O	IC50 = 82560 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0QR5V	3-(Hydroxymethyl)-6-(4-hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethynyl]benzoic acid	Investigative	122179777	C22H16O5	360.4	C1=CC(=CC=C1C#CC2=C(C=CC(=C2C(=O)O)C3=CC=C(C=C3)O)CO)O	IC50 = 85350 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0R2JB	6-[5-(5,7-Dihydroxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one	Investigative	11757331	C31H20O10	552.5	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C5=C(C=C4O)OC(=CC5=O)C6=CC=C(C=C6)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0S6NQ	N-(4-Amino-2-methylquinolin-6-yl)-3-isoquinolin-4-ylbenzamide	Investigative	73056179	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CN=CC5=CC=CC=C54)N	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B0U3TW	N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonyl(methyl)amino]acetamide	Investigative	72714083	C16H16Br2N2O5S	508.2	CN(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)OCC2=CC(=CC(=C2)Br)Br	IC50 = 123000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B0V4OK	Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445229	C16H11NO3	265.26	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=O)N3	IC50 = 109000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B0V4OK	Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445229	C16H11NO3	265.26	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=O)N3	IC50 = 109000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B0V4OK	Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445229	C16H11NO3	265.26	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=O)N3	IC50 = 111000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0V4OK	Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445229	C16H11NO3	265.26	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=O)N3	IC50 = 115000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B0W1VQ	4-[4-(Thiirane-2-ylmethylsulfonyl)phenoxy]phenol	Investigative	15941550	C15H14O4S2	322.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)O	Ki = 128000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B0X7FC	Ethyl 2-benzyl-3-(hydroxyamino)-3-oxopropanoate	Investigative	10728558	C12H15NO4	237.25	CCOC(=O)C(CC1=CC=CC=C1)C(=O)NO	Ki = 52480.75 nM	Poor binder
T80942	Matrix metalloproteinase 3	B12CRJ	N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide	Investigative	22096205	C16H31N3O4	329.43	CCCCC(CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B12CRJ	N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide	Investigative	22096205	C16H31N3O4	329.43	CCCCC(CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B12CRJ	N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide	Investigative	22096205	C16H31N3O4	329.43	CCCCC(CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B12CRJ	N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide	Investigative	22096205	C16H31N3O4	329.43	CCCCC(CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B15CBA	Chembl4215930	Investigative	145973485	C52H60N4O5S	853.1	CC1=CC=C(C=C1)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@]3(CCC[C@]4([C@H]3CCC5=CC(=C(C=C54)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)C)C(C)C)C)C	IC50 = 51600 nM	Poor binder
T80942	Matrix metalloproteinase 9	B15ZCJ	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)aminobutanoic acid	Investigative	70941086	C17H20N2O5S	364.4	CC[C@@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)OC	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B15ZCJ	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)aminobutanoic acid	Investigative	70941086	C17H20N2O5S	364.4	CC[C@@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B17OXB	(2R)-N-Hydroxy-2-[(biphenyl-4-ylcarbonyl)amino]-3-phenylpropanamide	Investigative	10832371	C22H20N2O3	360.4	C1=CC=C(C=C1)C[C@H](C(=O)NO)NC(=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B18KLZ	(4S,E)-5-(1,4-Dimethoxy-1,4-dioxobutan-2-ylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582720	C22H28N2O10	480.5	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC(CC(=O)OC)C(=O)OC)OC	IC50 = 101500 nM	Poor binder
T80942	Matrix metalloproteinase 1	B19UTG	N-(4-Amino-2-methylquinolin-6-yl)-4-isoquinolin-4-ylbenzamide	Investigative	73055903	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)C4=CN=CC5=CC=CC=C54)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1AHC5	4-Phenylbutyl[1-(4-phenylbutyl)-3-(4-phenoxyphenyl)ureidoacetyl]aminoacetohydroximic acid	Investigative	44328283	C37H42N4O5	622.8	C1=CC=C(C=C1)CCCCN(CC(=O)NO)C(=O)CN(CCCCC2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)OC4=CC=CC=C4	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1B7TI	Chembl4208066	Investigative	145976464	C31H22O5	474.5	C1=CC(=CC=C1C2=CC(=CC(=C2C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)C(=O)C5=CC=C(C=C5)O)O	IC50 = 54180 nM	Poor binder
T80942	Matrix metalloproteinase 3	B1B7TI	Chembl4208066	Investigative	145976464	C31H22O5	474.5	C1=CC(=CC=C1C2=CC(=CC(=C2C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)C(=O)C5=CC=C(C=C5)O)O	IC50 = 66120 nM	Poor binder
T80942	Matrix metalloproteinase 9	B1B7TI	Chembl4208066	Investigative	145976464	C31H22O5	474.5	C1=CC(=CC=C1C2=CC(=CC(=C2C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)C(=O)C5=CC=C(C=C5)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B1BUA7	2-Thioxo-5-hexyl-5-(4-biphenylyl)hexahydropyrimidine-4,6-dione	Investigative	44384941	C22H24N2O2S	380.5	CCCCCCC1(C(=O)NC(=S)NC1=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1CEG0	[(4-Bromophenyl)sulfonyl-phosphonomethyl]phosphonic acid	Investigative	90644157	C7H9BrO8P2S	395.06	C1=CC(=CC=C1S(=O)(=O)C(P(=O)(O)O)P(=O)(O)O)Br	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B1DGY0	(R)-3-((S)-1-((S)-2-Methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl)-6-(2-methylbiphenyl-4-YL)hexanoic acid	Investigative	9808181	C35H44N2O5	572.7	CC1=C(C=CC(=C1)CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](COC)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3	IC50 = 66900 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1DGY0	(R)-3-((S)-1-((S)-2-Methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl)-6-(2-methylbiphenyl-4-YL)hexanoic acid	Investigative	9808181	C35H44N2O5	572.7	CC1=C(C=CC(=C1)CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](COC)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1DWZ7	(2S)-2-Amino-N-[(3S)-1-[2-(4-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863915	C22H23FN4O4	426.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC=C(C=C3)F	IC50 = 122000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1JOV0	5-[2-[4-(3-Chlorophenyl)phenyl]-2-oxoethyl]-5-hydroxy-1,3-diazinane-2,4,6-trione	Investigative	71451167	C18H13ClN2O5	372.8	C1=CC(=CC(=C1)Cl)C2=CC=C(C=C2)C(=O)CC3(C(=O)NC(=O)NC3=O)O	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1JQZ0	(2S)-2-[(7,7-Dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methylsulfonylamino]-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide	Investigative	90663080	C24H31N5O5S3	565.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)CC34CCC(C3(C)C)CC4=O	Ki = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B1L8EV	4-(5-Bromo-4-methyl-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485513	C11H10BrN5	292.13	CC1=C(NC(=C1)C2=NC=CC3=C2N=C(N3)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1LX9I	(R)-2-(5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamido)acetic acid	Investigative	10271240	C17H26N4O6	382.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NCC(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1M5KY	N-Hydroxy-2-[4-(4-bromobenzyloxy)phenylsulfonylamino]acetamide	Investigative	72713638	C15H15BrN2O5S	415.3	C1=CC(=CC=C1COC2=CC=C(C=C2)S(=O)(=O)NCC(=O)NO)Br	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1N2DW	Chembl4213048	Investigative	25212135	C31H22O10	554.5	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C5=C(C=C4O)OC(CC5=O)C6=CC=C(C=C6)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1OFL3	Hexyl 6-mercaptopicolinate	Investigative	44445270	C12H17NO2S	239.34	CCCCCCOC(=O)C1=CC=CC(=S)N1	IC50 = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B1OFL3	Hexyl 6-mercaptopicolinate	Investigative	44445270	C12H17NO2S	239.34	CCCCCCOC(=O)C1=CC=CC(=S)N1	IC50 = 105000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B1OFL3	Hexyl 6-mercaptopicolinate	Investigative	44445270	C12H17NO2S	239.34	CCCCCCOC(=O)C1=CC=CC(=S)N1	IC50 = 109000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1OFL3	Hexyl 6-mercaptopicolinate	Investigative	44445270	C12H17NO2S	239.34	CCCCCCOC(=O)C1=CC=CC(=S)N1	IC50 = 115000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B1PXZ7	N-(4-Amino-2-methylquinolin-6-yl)-3-[4-(dimethylamino)phenyl]benzamide	Investigative	73055014	C25H24N4O	396.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CC=C(C=C4)N(C)C)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B1QVT8	5-((5-Methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dione	Investigative	11716217	C13H14N4O4	290.27	CC1(C(=O)NC(=O)N1)CN2C(=O)C3=C(N2)C=CC(=C3)OC	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1RLZ5	4-[2-[Formyl(hydroxy)amino]-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropyl]benzoic acid	Investigative	90667651	C24H20F3NO8S	539.5	C1=CC(=CC=C1CC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B1SJO6	N-[(E)-(4-Dimethylaminophenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide	Investigative	14616301	C20H21N5O2	363.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=CC=C(C=C3)N(C)C	IC50 = 64300 nM	Poor binder
T80942	Matrix metalloproteinase 3	B1YM9Q	(Methylamino)carbonylphosphonic acid	Investigative	11457732	C2H6NO4P	139.05	CNC(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B1YM9Q	(Methylamino)carbonylphosphonic acid	Investigative	11457732	C2H6NO4P	139.05	CNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1YM9Q	(Methylamino)carbonylphosphonic acid	Investigative	11457732	C2H6NO4P	139.05	CNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B1ZH3O	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-1-hydroxyurea	Investigative	44286406	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCN(C(=O)N)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B1ZH3O	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-1-hydroxyurea	Investigative	44286406	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCN(C(=O)N)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B1ZWH9	(2R)-N-[[(4R)-4-Cyclopropyl-2,5-dioxo-imidazolidin-4-yl]methyl]-2-[[4-(trifluoromethyl)phenyl]methyl]butanamide	Investigative	73603957	C19H22F3N3O3	397.4	CC[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B21ZFK	Thioacetic acid S-((4S,5S)-2-p-tolyl-5-vinyl-4,5-dihydro-oxazol-4-yl) ester	Investigative	44394796	C14H15NO2S	261.339	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)SC(=O)C	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B25XRZ	Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid	Investigative	9817594	C12H27N2O4P	294.33	CC(C)CCNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B25XRZ	Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid	Investigative	9817594	C12H27N2O4P	294.33	CC(C)CCNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B25XRZ	Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid	Investigative	9817594	C12H27N2O4P	294.33	CC(C)CCNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B25XRZ	Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid	Investigative	9817594	C12H27N2O4P	294.33	CC(C)CCNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B26QZF	1-(4-Methoxy-phenyl)-3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-urea	Investigative	10636628	C10H10N4O2S2	282.3	COC1=CC=C(C=C1)NC(=O)NC2=NNC(=S)S2	Ki = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2AP9E	2-[1-Sec-Butyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-N-isopropyl-acetamide	Investigative	44327940	C24H32N4O5	456.5	CCC(C)N(CC(=O)N(CC(=O)NO)C(C)C)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B2APB0	(R)-2-(N-((2-Fluoropyridin-3-yl)methyl)-4-methoxyphenylsulphonamido)-3-methylbutanoic acid	Investigative	23657695	C18H21FN2O5S	396.4	CC(C)[C@H](C(=O)O)N(CC1=C(N=CC=C1)F)S(=O)(=O)C2=CC=C(C=C2)OC	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2AR5L	2-Phenoxyethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445211	C14H13NO4	259.26	C1=CC=C(C=C1)OCCOC(=O)C2=CC=CC(=O)N2	IC50 = 59000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B2AR5L	2-Phenoxyethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445211	C14H13NO4	259.26	C1=CC=C(C=C1)OCCOC(=O)C2=CC=CC(=O)N2	IC50 = 79000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2AR5L	2-Phenoxyethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445211	C14H13NO4	259.26	C1=CC=C(C=C1)OCCOC(=O)C2=CC=CC(=O)N2	IC50 = 127000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2E8YD	4-{3-(Formyl-hydroxy-amino)-4-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-butyl}-benzoic acid methyl ester	Investigative	10303333	C26H24F3NO8S	567.5	COC(=O)C1=CC=C(C=C1)CCC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B2EDN9	3-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445251	C14H13NO3S	275.32	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2EDN9	3-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445251	C14H13NO3S	275.32	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 86000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2EDN9	3-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445251	C14H13NO3S	275.32	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2EDN9	3-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445251	C14H13NO3S	275.32	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 93000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2EP1H	N-Hydroxy-2-[4-(3,5-difluorobenzyloxy)phenylsulfonylamino]acetamide	Investigative	72714081	C15H14F2N2O5S	372.3	C1=CC(=CC=C1OCC2=CC(=CC(=C2)F)F)S(=O)(=O)NCC(=O)NO	IC50 = 181000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2G4CK	(S)-2-(Acetyl-methyl-amino)-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-propionamide	Investigative	44325234	C18H20N2O6S	392.4	CC(=O)N(C)[C@H](CS(=O)(=O)C1=CC=C(C=C1)OC2=CC=CC=C2)C(=O)NO	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B2GW6F	(P-Tolylamino)methylenediphosphonic acid	Investigative	13738810	C8H13NO6P2	281.14	CC1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2GW6F	(P-Tolylamino)methylenediphosphonic acid	Investigative	13738810	C8H13NO6P2	281.14	CC1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2GW6F	(P-Tolylamino)methylenediphosphonic acid	Investigative	13738810	C8H13NO6P2	281.14	CC1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2H5RK	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-5-ylbenzamide	Investigative	73056180	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=C5C=CC=NC5=CC=C4)N	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2H5RK	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-5-ylbenzamide	Investigative	73056180	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=C5C=CC=NC5=CC=C4)N	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B2I7UA	1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445277	C14H14N4O	254.29	C1COC(=N1)C2=CN(N=N2)C/C=C/C3=CC=CC=C3	IC50 = 61000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2I7UA	1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445277	C14H14N4O	254.29	C1COC(=N1)C2=CN(N=N2)C/C=C/C3=CC=CC=C3	IC50 = 149000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2I7UA	1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445277	C14H14N4O	254.29	C1COC(=N1)C2=CN(N=N2)C/C=C/C3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2I7UA	1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445277	C14H14N4O	254.29	C1COC(=N1)C2=CN(N=N2)C/C=C/C3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2J6IN	N-[(2S,4S)-1-[4-[2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide	Investigative	53320226	C24H30ClF4N5O4S	596	C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CC1)CCC2=C(C=C(C=N2)C(F)(F)F)Cl)N(C=O)O)C3=NC=C(C=N3)F	IC50 ~ 70000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 = 79600 nM	Poor binder
T80942	Matrix metalloproteinase 14	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2KX4H	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-4-methylpentanamide	Investigative	44199512	C15H24N4O4	324.38	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)[N+](=O)[O-])O)N)N	IC50 = 142900 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2LIP5	3-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445254	C13H10FNO2S	263.29	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 107000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2LIP5	3-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445254	C13H10FNO2S	263.29	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 119000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2LIP5	3-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445254	C13H10FNO2S	263.29	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 124000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B2LIP5	3-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445254	C13H10FNO2S	263.29	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 151000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2MO8B	(3R)-6-Cyclohexyl-N-hydroxy-3-{3-[1-(methylsulfonyl)-4-piperidinyl]-1,2,4-oxadiazol-5-yl}hexanamide	Investigative	44425142	C21H37N5O5S	471.6	CS(=O)(=O)N1CCC(CC1)NCC2=NOC(=N2)[C@H](CCCC3CCCCC3)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2OI6X	(E)-5-(4-Hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide	Investigative	49806131	C26H21NO5	427.4	C1=CC=C(C=C1)NC(=O)C(C(=O)/C=C/C2=CC=C(C=C2)O)C(=O)/C=C/C3=CC=C(C=C3)O	IC50 = 125000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B2PDW6	3-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445267	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=CC(=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2PDW6	3-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445267	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=CC(=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2PDW6	3-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445267	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=CC(=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2RL6A	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]-4-methylpentanamide	Investigative	56661895	C15H24IN3O2	405.27	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)I)O)N)N	IC50 = 119500 nM	Poor binder
T80942	Matrix metalloproteinase 13	B2UFY3	5-[5-[(4-Carboxyphenyl)methylcarbamoyl]-2-methylpyrazol-3-yl]-1H-indole-2-carboxylic acid	Investigative	45377567	C22H18N4O5	418.4	CN1C(=CC(=N1)C(=O)NCC2=CC=C(C=C2)C(=O)O)C3=CC4=C(C=C3)NC(=C4)C(=O)O	IC50 = 56000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B2VC9Y	5-Chloro-N-{[(4s)-4-(1-Methyl-1h-Imidazol-2-Yl)-2,5-Dioxoimidazolidin-4-Yl]methyl}-1-Benzofuran-2-Carboxamide	Investigative	86287516	C17H14ClN5O4	387.8	CN1C=CN=C1[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2VD5N	Methyl (8S)-7-(4-nitrophenyl)sulfonyl-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylate	Investigative	72737560	C14H16N2O6S3	404.5	COC(=O)[C@@H]1CC2(CN1S(=O)(=O)C3=CC=C(C=C3)[N+](=O)[O-])SCCS2	IC50 = 77930 nM	Poor binder
T80942	Matrix metalloproteinase 9	B2VS5T	(2R)-4-Fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]butanoic acid	Investigative	70941155	C17H19FN2O5S	382.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@H](CCF)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2VS5T	(2R)-4-Fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]butanoic acid	Investigative	70941155	C17H19FN2O5S	382.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@H](CCF)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B2XM4O	N-Hydroxy-2-[[4-[(3-phenylphenyl)methoxy]phenyl]sulfonylamino]acetamide	Investigative	72713867	C21H20N2O5S	412.5	C1=CC=C(C=C1)C2=CC=CC(=C2)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B2XYU7	2-(1-Benzyl-3-naphthalen-1-yl-ureido)-N-sec-butyl-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328295	C26H30N4O4	462.5	CCC(C)N(CC(=O)NO)C(=O)CN(CC1=CC=CC=C1)C(=O)NC2=CC=CC3=CC=CC=C32	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B30VXW	(E)-N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methoxyphenyl)prop-2-enamide	Investigative	73056185	C20H19N3O2	333.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)/C=C/C3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B30VXW	(E)-N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methoxyphenyl)prop-2-enamide	Investigative	73056185	C20H19N3O2	333.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)/C=C/C3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B32QID	(S)-2-(2-(3-Methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-N,3-diphenylpropanamide	Investigative	46233057	C26H24N4O3	440.5	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NC4=CC=CC=C4	IC50 = 58140 nM	Poor binder
T80942	Matrix metalloproteinase 1	B34QYF	N-[(2S)-3-(4-Methoxyphenyl)-1-(methylamino)-1-oxopropan-2-yl]-4-methyl-2-[(2-sulfanylidene-1H-pyridin-3-yl)methyl]pentanamide	Investigative	44333861	C23H31N3O3S	429.6	CC(C)CC(CC1=CC=CNC1=S)C(=O)N[C@@H](CC2=CC=C(C=C2)OC)C(=O)NC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B35HBC	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]hexanamide	Investigative	44356767	C32H51N7O5	613.8	CCCC[C@@H](C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCC)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H](C)N	IC50 ~ 60000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B35MBR	(1R,2S,5R)-2-[4-(4-Chlorophenyl)phenyl]sulfonyl-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	11135133	C26H22ClN3O5S	524	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)S(=O)(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B35NLF	2,6-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445216	C13H9F2NO3	265.21	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B35NLF	2,6-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445216	C13H9F2NO3	265.21	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B35NLF	2,6-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445216	C13H9F2NO3	265.21	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 66000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B36MJV	5-[4-(4-Acetylphenyl)phenyl]-3-hydroxypentanoic acid	Investigative	11335940	C19H20O4	312.4	CC(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B36ZMF	4-(4,5-Dibromo-1H-pyrrol-2-yl)-N,1-dimethyl-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	44426076	C12H11Br2N5	385.06	CNC1=NC2=C(N1C)C=CN=C2C3=CC(=C(N3)Br)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B37QZM	(S)-3-Cyclohexyl-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide	Investigative	10854874	C13H21N5O2S2	343.5	CNC(=O)[C@H](CC1CCCCC1)NC(=O)NC2=NNC(=S)S2	Ki = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B38APD	(S)-3-Benzyloxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide	Investigative	10595134	C14H17N5O3S2	367.5	CNC(=O)[C@H](COCC1=CC=CC=C1)NC(=O)NC2=NNC(=S)S2	Ki = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B39ANH	Ethyl 5-(methanesulfonamido)-1H-indole-2-carboxylate	Investigative	53957122	C12H14N2O4S	282.32	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)NS(=O)(=O)C	IC50 = 97000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3BU8I	N-[(2S,4S)-1-[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide	Investigative	53325499	C25H36FN5O4S	521.6	CC1=CC(=C(C=N1)C)CCC2CCN(CC2)S(=O)(=O)C[C@](C)(C[C@H](C)C3=NC=C(C=N3)F)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3C1QJ	(2S)-N-[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2R)-2-aminopropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanamide	Investigative	44356774	C26H40N6O4	500.6	CCCC[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H](C)N	IC50 ~ 60000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3C6LK	2-(2-Mercapto-benzyl)-4-methyl-pentanoic acid (2-oxo-azacyclotridec-3-yl)-amide	Investigative	44333652	C25H40N2O2S	432.7	CC(C)CC(CC1=CC=CC=C1S)C(=O)NC2CCCCCCCCCCNC2=O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3DWU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(2-hydroxy-1,1-dimethylethyl)amino]methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10293283	C19H34N4O4	382.5	CC(C)(CO)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3EAC2	N-[(2S,4S)-1-[4-[2-(2,5-Dimethylpyridin-3-yl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide	Investigative	53322877	C25H36FN5O4S	521.6	CC1=CC(=C(N=C1)C)CCC2CCN(CC2)S(=O)(=O)C[C@](C)(C[C@H](C)C3=NC=C(C=N3)F)N(C=O)O	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3ET7X	(3S)-N-[(2S)-1-(Hydroxyamino)-4-methylsulfanyl-1-oxobutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride	Investigative	56659953	C15H22ClN3O3S	359.9	CSCC[C@@H](C(=O)NO)NC(=O)[C@@H]1CC2=CC=CC=C2CN1.Cl	IC50 = 166110 nM	Poor binder
T80942	Matrix metalloproteinase 14	B3EUN1	[(3-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205111	C7H10FNO6P2	285.1	C1=CC(=CC(=C1)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B3EUN1	[(3-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205111	C7H10FNO6P2	285.1	C1=CC(=CC(=C1)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3EUN1	[(3-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205111	C7H10FNO6P2	285.1	C1=CC(=CC(=C1)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B3F2EQ	3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445279	C15H15N5	265.31	C1=CC=C(C=C1)CCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3F2EQ	3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445279	C15H15N5	265.31	C1=CC=C(C=C1)CCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3F2EQ	3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445279	C15H15N5	265.31	C1=CC=C(C=C1)CCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3F2EQ	3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445279	C15H15N5	265.31	C1=CC=C(C=C1)CCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3FI7C	N-Hydroxybenzenesulfonamide	Investigative	69033	C6H7NO3S	173.19	C1=CC=C(C=C1)S(=O)(=O)NO	Ki = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B3FI7C	N-Hydroxybenzenesulfonamide	Investigative	69033	C6H7NO3S	173.19	C1=CC=C(C=C1)S(=O)(=O)NO	Ki = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3FI7C	N-Hydroxybenzenesulfonamide	Investigative	69033	C6H7NO3S	173.19	C1=CC=C(C=C1)S(=O)(=O)NO	Ki = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3FI7C	N-Hydroxybenzenesulfonamide	Investigative	69033	C6H7NO3S	173.19	C1=CC=C(C=C1)S(=O)(=O)NO	Ki = 79000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3H1MQ	3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylsulfamoyl]-5-methyl-hexanoic acid	Investigative	44315179	C18H28N2O6S	400.5	CC(C)CC(CC(=O)O)S(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)NC	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3HJ0N	Hydroxysulfonamide 49	Investigative	23645539	C4H2F9NO3S	315.12	C(C(C(F)(F)S(=O)(=O)NO)(F)F)(C(F)(F)F)(F)F	Ki = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B3I0TD	5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione	Investigative	9823182	C24H20N2O5	416.4	C1=CC=C(C=C1)COCC2(C(=O)NC(=O)NC2=O)C3=CC=C(C=C3)OC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3JXS1	(2R)-4-Fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]pent-4-enoic acid	Investigative	71465467	C18H19FN2O5S	394.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@H](CC(=C)F)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3KE7Z	[(4-Phenylanilino)-phosphono-methyl]phosphonic acid	Investigative	5277465	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC=C(C=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3KE7Z	[(4-Phenylanilino)-phosphono-methyl]phosphonic acid	Investigative	5277465	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC=C(C=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B3M5RK	4-[3,5-Dibromo-4-[2-(trifluoromethyl)phenethyl]-1H-pyrrole-2-yl]-1H-imidazo[4,5-c]pyridine-2-amine	Investigative	45485558	C19H14Br2F3N5	529.2	C1=CC=C(C(=C1)CCC2=C(NC(=C2Br)C3=NC=CC4=C3N=C(N4)N)Br)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3NPE5	2,5-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445257	C13H9F2NO2S	281.28	C1=CC(=S)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 79000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3NPE5	2,5-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445257	C13H9F2NO2S	281.28	C1=CC(=S)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 114000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3NPE5	2,5-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445257	C13H9F2NO2S	281.28	C1=CC(=S)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 140000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B3S5OF	4-Chloro-N-hydroxybenzene-1-sulfonamide	Investigative	352863	C6H6ClNO3S	207.64	C1=CC(=CC=C1S(=O)(=O)NO)Cl	Ki = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3S5OF	4-Chloro-N-hydroxybenzene-1-sulfonamide	Investigative	352863	C6H6ClNO3S	207.64	C1=CC(=CC=C1S(=O)(=O)NO)Cl	Ki = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3S5OF	4-Chloro-N-hydroxybenzene-1-sulfonamide	Investigative	352863	C6H6ClNO3S	207.64	C1=CC(=CC=C1S(=O)(=O)NO)Cl	Ki = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3S5OF	4-Chloro-N-hydroxybenzene-1-sulfonamide	Investigative	352863	C6H6ClNO3S	207.64	C1=CC(=CC=C1S(=O)(=O)NO)Cl	Ki = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B3T2HA	Chembl4215193	Investigative	145972073	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B3T2HA	Chembl4215193	Investigative	145972073	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3T2HA	Chembl4215193	Investigative	145972073	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B3TS1F	2-[3-(4-Biphenylyloxymethyl)-4-oxo-4-(hydroxyamino)butyl]-3-oxo-2,3-dihydro-1,2-benzisothiazole 1,1-dioxide	Investigative	9934240	C24H22N2O6S	466.5	C1=CC=C(C=C1)C2=CC=C(C=C2)OCC(CCN3C(=O)C4=CC=CC=C4S3(=O)=O)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B3VCP2	5-Chloro-2-oxo-1,2,3,4-tetrahydroquinazoline-3-acetohydroxamic acid	Investigative	10467565	C10H10ClN3O3	255.66	C1C2=C(C=CC=C2Cl)NC(=O)N1CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B3WAP8	Procyanidin C1	Investigative	169853	C45H38O18	866.8	C1[C@H]([C@H](OC2=C1C(=CC(=C2[C@@H]3[C@H]([C@H](OC4=C(C(=CC(=C34)O)O)[C@@H]5[C@H]([C@H](OC6=CC(=CC(=C56)O)O)C7=CC(=C(C=C7)O)O)O)C8=CC(=C(C=C8)O)O)O)O)O)C9=CC(=C(C=C9)O)O)O	IC50 = 53200 nM	Poor binder
T80942	Matrix metalloproteinase 14	B3YB7F	N-Hydroxy-2-[4-(8-quinolylmethoxy)phenylsulfonylamino]acetamide	Investigative	72713868	C18H17N3O5S	387.4	C1=CC2=C(C(=C1)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO)N=CC=C2	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B3Z2SA	N-((R)-1-Benzylcarbamoyl-ethyl)-N''-hydroxy-2-isobutyl-malonamide	Investigative	10544776	C17H25N3O4	335.4	C[C@H](C(=O)NCC1=CC=CC=C1)NC(=O)C(CC(C)C)C(=O)NO	Ki = 194000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B3Z5RU	(5Z)-5-(3-Phenoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one	Investigative	6005649	C16H11NO2S2	313.4	C1=CC=C(C=C1)OC2=CC=CC(=C2)/C=C\\3/C(=O)NC(=S)S3	IC50 = 55270 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3ZCW8	(R)-5-(4-Chlorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582887	C21H23ClN2O7	450.9	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Cl	IC50 = 52300 nM	Poor binder
T80942	Matrix metalloproteinase 2	B3ZM4Y	(R)-6-Cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carbonyl)-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10111132	C20H32N4O4	392.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)N3CCCCC3	IC50 = 74900 nM	Poor binder
T80942	Matrix metalloproteinase 2	B41BIN	2,6-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445256	C13H9F2NO2S	281.28	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=S)N2)F	IC50 = 66000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B41BIN	2,6-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445256	C13H9F2NO2S	281.28	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=S)N2)F	IC50 = 92000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B41BIN	2,6-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445256	C13H9F2NO2S	281.28	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=S)N2)F	IC50 = 101000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B41BIN	2,6-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445256	C13H9F2NO2S	281.28	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=S)N2)F	IC50 = 127000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B41JRW	Berkchaetoazaphilone A	Investigative	127028674	C25H34O6	430.5	CCCCCCCCCC(=O)[C@H]1[C@@H]2C3=COC(=CC3=CC(=O)[C@@]2(OC1=O)C)C[C@H](C)O	IC50 = 130000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B41WTH	5-Hexyl-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione	Investigative	9886177	C22H24N2O4	380.4	CCCCCCC1(C(=O)NC(=O)NC1=O)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B43XGE	Chembl4211708	Investigative	145964366	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7OC	IC50 = 52500 nM	Poor binder
T80942	Matrix metalloproteinase 9	B43XGE	Chembl4211708	Investigative	145964366	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7OC	IC50 = 56200 nM	Poor binder
T80942	Matrix metalloproteinase 2	B46JHV	Chembl4206592	Investigative	46873064	C27H20O6	440.4	C1=CC(=CC=C1C2=C3C(=C(C=C2)CO)C(=O)OC3(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O)O	IC50 = 53670 nM	Poor binder
T80942	Matrix metalloproteinase 3	B46JHV	Chembl4206592	Investigative	46873064	C27H20O6	440.4	C1=CC(=CC=C1C2=C3C(=C(C=C2)CO)C(=O)OC3(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O)O	IC50 = 87770 nM	Poor binder
T80942	Matrix metalloproteinase 13	B46STP	4-Phenoxy-N-[(1R,2S)-2-sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682766	C17H19NO3S2	349.5	C1C[C@H]([C@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B46STP	4-Phenoxy-N-[(1R,2S)-2-sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682766	C17H19NO3S2	349.5	C1C[C@H]([C@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B48YSV	US9187406, Curcumin	Investigative	58963267	C21H20O6	368.4	COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)CO)O	IC50 = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B48YSV	US9187406, Curcumin	Investigative	58963267	C21H20O6	368.4	COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)CO)O	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B49VDF	4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445210	C14H13NO4	259.26	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 99000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B49VDF	4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445210	C14H13NO4	259.26	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B49VDF	4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445210	C14H13NO4	259.26	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 105000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B49VDF	4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445210	C14H13NO4	259.26	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B4A9NL	N-Benzhydryl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide	Investigative	44327780	C39H38N4O5	642.7	C1=CC=C(C=C1)CCCN(CC(=O)N(CC(=O)NO)C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B4DIP9	(2R)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-phenylpropanamide	Investigative	56678865	C18H22N4O4	358.4	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N	IC50 = 67400 nM	Poor binder
T80942	Matrix metalloproteinase 8	B4FXQ5	N*1*-Benzyl-2-(2-hydroxycarbamoyl-4-methyl-pentanoylamino)-succinamide	Investigative	44343240	C18H26N4O5	378.4	CC(C)CC(C(=O)NC(CC(=O)N)C(=O)NCC1=CC=CC=C1)C(=O)NO	Ki = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B4GX3O	(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methyl-N-[(1R)-1-phenylethyl]pentanamide	Investigative	44356775	C28H37N5O3	491.6	C[C@H](C1=CC=CC=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H](C)N	IC50 ~ 60000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B4H0TJ	2,3-Bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxypropanamide	Investigative	44576807	C19H25N3O10S2	519.6	COC1=CC(=C(C=C1)S(=O)(=O)NCC(C(=O)NO)NS(=O)(=O)C2=C(C=C(C=C2)OC)OC)OC	Ki = 124000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B4J1FW	6-Amino-N-[(2R)-2-amino-3-phenylpropyl]caproylamide	Investigative	42645513	C15H25N3O	263.38	C1=CC=C(C=C1)C[C@H](CNC(=O)CCCCCN)N	IC50 = 99700 nM	Poor binder
T80942	Matrix metalloproteinase 12	B4KXM7	4-(5-Bromo-4-(3-phenylpropyl)-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485463	C19H18BrN5	396.3	C1=CC=C(C=C1)CCCC2=C(NC(=C2)C3=NC=CC4=C3N=C(N4)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B4M7LO	4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sulfonate	Investigative	53323418	C13H18O5S3	350.5	CC(C)CS(=O)(=O)OC1=CC=C(C=C1)S(=O)(=O)CC2CS2	Ki = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B4MG9X	2-(N-Methyl-N-phenylamino)-N-((5-chloro-8-hydroxyquinolin-7-yl)(3-nitrophenyl)methyl)acetamide	Investigative	24958549	C25H21ClN4O4	476.9	CN(CC(=O)NC(C1=CC(=CC=C1)[N+](=O)[O-])C2=CC(=C3C=CC=NC3=C2O)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B4MKA1	N-(p-Fluorobenzenesulfonyl)hydroxylamine	Investigative	12635074	C6H6FNO3S	191.18	C1=CC(=CC=C1F)S(=O)(=O)NO	Ki = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B4MKA1	N-(p-Fluorobenzenesulfonyl)hydroxylamine	Investigative	12635074	C6H6FNO3S	191.18	C1=CC(=CC=C1F)S(=O)(=O)NO	Ki = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B4MKA1	N-(p-Fluorobenzenesulfonyl)hydroxylamine	Investigative	12635074	C6H6FNO3S	191.18	C1=CC(=CC=C1F)S(=O)(=O)NO	Ki = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B4MKA1	N-(p-Fluorobenzenesulfonyl)hydroxylamine	Investigative	12635074	C6H6FNO3S	191.18	C1=CC(=CC=C1F)S(=O)(=O)NO	Ki = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B4NH7Q	4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide	Investigative	4358655	C20H18N2O2	318.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 = 50118.72 nM	Poor binder
T80942	Matrix metalloproteinase 12	B4NH7Q	4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide	Investigative	4358655	C20H18N2O2	318.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B4NH7Q	4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide	Investigative	4358655	C20H18N2O2	318.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B4NH7Q	4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide	Investigative	4358655	C20H18N2O2	318.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B4O5BS	3-Methylbut-2-enyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445201	C11H13NO3	207.23	CC(=CCOC(=O)C1=CC=CC(=O)N1)C	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B4O5BS	3-Methylbut-2-enyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445201	C11H13NO3	207.23	CC(=CCOC(=O)C1=CC=CC(=O)N1)C	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B4O5BS	3-Methylbut-2-enyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445201	C11H13NO3	207.23	CC(=CCOC(=O)C1=CC=CC(=O)N1)C	IC50 = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B4R5IC	(2R,3Ar,7aR)-1-[2-[[4-[[4-chloro-3-[[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylacetyl]sulfamoyl]benzoyl]sulfamoyl]benzoyl]amino]-3-methylbutanoyl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide	Investigative	44300181	C50H63ClF3N5O11S3	1098.7	CC(C)C(C(=O)C(F)(F)F)NC(=O)[C@H]1C[C@H]2CCCC[C@H]2N1C(=O)C(C(C)C)NC(=O)C3=CC=C(C=C3)S(=O)(=O)NC(=O)C4=CC(=C(C=C4)Cl)S(=O)(=O)NC(=O)CSC5=CC(=C(C(=C5)C(C)(C)C)O)C(C)(C)C	IC50 = 58000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B4U2AL	[(1S)-6-Fluoro-1-[[4-(4-methoxyphenyl)phenyl]sulfonylamino]hexyl]phosphonic acid	Investigative	127025166	C19H25FNO6PS	445.4	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)N[C@H](CCCCCF)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B4VDK7	Epicatechin 3-O-(4-O-methylgallate)	Investigative	467297	C23H20O10	456.4	COC1=C(C=C(C=C1O)C(=O)O[C@@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B4YJN3	[4-[4-(Thiiran-2-ylmethylsulfonyl)phenoxy]phenyl] N-propylcarbamate	Investigative	72714334	C19H21NO5S2	407.5	CCCNC(=O)OC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)CC3CS3	Ki = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B4ZP8S	1-[[2-(4-Chlorophenoxy)acetyl]amino]-3-(4-cyclohexylbutyl)thiourea	Investigative	73349535	C19H28ClN3O2S	398	C1CCC(CC1)CCCCNC(=S)NNC(=O)COC2=CC=C(C=C2)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B4ZP8S	1-[[2-(4-Chlorophenoxy)acetyl]amino]-3-(4-cyclohexylbutyl)thiourea	Investigative	73349535	C19H28ClN3O2S	398	C1CCC(CC1)CCCCNC(=S)NNC(=O)COC2=CC=C(C=C2)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B4ZP8S	1-[[2-(4-Chlorophenoxy)acetyl]amino]-3-(4-cyclohexylbutyl)thiourea	Investigative	73349535	C19H28ClN3O2S	398	C1CCC(CC1)CCCCNC(=S)NNC(=O)COC2=CC=C(C=C2)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B52RVN	4-(4-Benzyl-5-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485520	C17H14BrN5	368.2	C1=CC=C(C=C1)CC2=C(NC(=C2)C3=NC=CC4=C3N=C(N4)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B52VLK	N-[1-(Phenoxymethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid	Investigative	21700204	C23H20N2O4	388.4	C1=CC=C(C=C1)OCC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O	IC50 = 130000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B57RUH	Prop-2-enyl 2-[(E)-3-(4-bromophenyl)prop-2-enoyl]oxy-3-(3,4-dimethoxyphenyl)propanoate	Investigative	71654195	C23H23BrO6	475.3	COC1=C(C=C(C=C1)CC(C(=O)OCC=C)OC(=O)/C=C/C2=CC=C(C=C2)Br)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B59SNT	Thiadiazole derivative, 34	Investigative	24754251	C24H21N3O2S	415.5	CC1=CC2=C(C=C1)N(C(=O)C23NN=C(S3)C4=CC=C(C=C4)OC)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B5AB4X	(Propylamino)carbonylphosphonic acid	Investigative	11400989	C4H10NO4P	167.1	CCCNC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B5AB4X	(Propylamino)carbonylphosphonic acid	Investigative	11400989	C4H10NO4P	167.1	CCCNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5AZC3	N-Hydroxy-N-{3-morpholin-4-yl-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide	Investigative	10301524	C22H25F3N2O7S	518.5	C1COCCN1CCC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5B8FZ	Naphthalen-1-yl 6-mercaptopicolinate	Investigative	44445263	C16H11NO2S	281.3	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=S)N3	IC50 = 98000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B5B8FZ	Naphthalen-1-yl 6-mercaptopicolinate	Investigative	44445263	C16H11NO2S	281.3	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=S)N3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B5B8FZ	Naphthalen-1-yl 6-mercaptopicolinate	Investigative	44445263	C16H11NO2S	281.3	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=S)N3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5B8FZ	Naphthalen-1-yl 6-mercaptopicolinate	Investigative	44445263	C16H11NO2S	281.3	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=S)N3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5CZ4E	3-(3,4-Dimethoxyphenyl)-2-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]oxypropanoic acid	Investigative	53375373	C22H24O8	416.4	COC1=C(C=C(C=C1)CC(C(=O)O)OC(=O)/C=C/C2=CC(=C(C=C2)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5D0HM	Prop-2-enyl 3-(3,4-dimethoxyphenyl)-2-[(E)-3-(4-nitrophenyl)prop-2-enoyl]oxypropanoate	Investigative	71654355	C23H23NO8	441.4	COC1=C(C=C(C=C1)CC(C(=O)OCC=C)OC(=O)/C=C/C2=CC=C(C=C2)[N+](=O)[O-])OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5DE2F	N-(1,1':4',1''-Terbenzene-4-ylmethyl)-3-hydroxy-4-oxo-6-methyl-4H-pyran-2-carboxamide	Investigative	54724681	C26H21NO4	411.4	CC1=CC(=O)C(=C(O1)C(=O)NCC2=CC=C(C=C2)C3=CC=C(C=C3)C4=CC=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5DE2F	N-(1,1':4',1''-Terbenzene-4-ylmethyl)-3-hydroxy-4-oxo-6-methyl-4H-pyran-2-carboxamide	Investigative	54724681	C26H21NO4	411.4	CC1=CC(=O)C(=C(O1)C(=O)NCC2=CC=C(C=C2)C3=CC=C(C=C3)C4=CC=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5H7VZ	5-[4-[[3-Azido-5-(azidomethyl)benzoyl]amino]phenyl]-N-[7-(hydroxyamino)-7-oxoheptyl]-1,2-oxazole-3-carboxamide	Investigative	53361475	C25H26N10O5	546.5	C1=CC(=CC=C1C2=CC(=NO2)C(=O)NCCCCCCC(=O)NO)NC(=O)C3=CC(=CC(=C3)CN=[N+]=[N-])N=[N+]=[N-]	IC50 = 108000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B5INQ8	3-(1-Phenyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-2H-chromen-2-one	Investigative	3380837	C18H12N2O2S	320.4	C1=CC=C(C=C1)N2C=C(NC2=S)C3=CC4=CC=CC=C4OC3=O	IC50 = 177000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5J4OW	(R)-5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-methyl-N-(pyridin-2-ylmethyl)-1,2,4-oxadiazole-3-carboxamide	Investigative	44571513	C22H31N5O4	429.5	CN(CC1=CC=CC=N1)C(=O)C2=NOC(=N2)[C@H](CCCC3CCCCC3)CC(=O)NO	IC50 = 50500 nM	Poor binder
T80942	Matrix metalloproteinase 14	B5K0FT	3-{1-[(Methoxy-phenyl-methyl)-carbamoyl]-2,2-dimethyl-propylcarbamoyl}-6-(2-methyl-biphenyl-4-yl)-hexanoic acid	Investigative	44344631	C34H42N2O5	558.7	CC1=C(C=CC(=C1)CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C2=CC=CC=C2)OC)C(C)(C)C)C3=CC=CC=C3	IC50 = 66900 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5MES1	N-[3,3-Dimethyl-1-oxo-1-(1-phenylethylamino)butan-2-yl]-N'-hydroxy-2-[3-[4-phenyl-3-(trifluoromethyl)phenyl]propyl]butanediamide	Investigative	75018171	C34H40F3N3O4	611.7	CC(C1=CC=CC=C1)NC(=O)C(C(C)(C)C)NC(=O)C(CCCC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CC(=O)NO	IC50 = 51999.6 nM	Poor binder
T80942	Matrix metalloproteinase 9	B5OC0L	CID 50943150	Investigative	50943150	C18H11N3S2	333.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5OC0L	CID 50943150	Investigative	50943150	C18H11N3S2	333.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5OC0L	CID 50943150	Investigative	50943150	C18H11N3S2	333.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5Q8ZA	N-(2-Methyl-4-amino-6-quinolyl)-4-(6-quinolyl)benzamide	Investigative	73055013	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)C4=CC5=C(C=C4)N=CC=C5)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5S7LF	2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclopentanecarboxylic acid	Investigative	11091928	C28H25NO4S	471.6	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3C2=O)C(=O)O)SCC4=CC=C(C=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5ST1I	Methyl (2S)-2-benzamido-3-(4-phenylmethoxyphenyl)propanoate	Investigative	71452970	C24H23NO4	389.4	COC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	IC50 = 67500 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5UYG2	L-Phenylalanyl-N-[(2R)-2-amino-3-phenylpropyl]-L-phenylalaninamide	Investigative	25147768	C27H32N4O2	444.6	C1=CC=C(C=C1)C[C@H](CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=CC=C3)N)N	IC50 = 182900 nM	Poor binder
T80942	Matrix metalloproteinase 2	B5VX3S	(2S)-2-Amino-N-[(3S)-1-[2-(3-chloro-4-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863954	C22H22ClFN4O4	460.9	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC(=C(C=C3)F)Cl	IC50 = 131000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B5ZP7Q	3-Acetoxy-5-(biphenyl-4-yl)pentanoic acid	Investigative	45482999	C19H20O4	312.4	CC(=O)OC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 = 54400 nM	Poor binder
T80942	Matrix metalloproteinase 13	B5ZP7Q	3-Acetoxy-5-(biphenyl-4-yl)pentanoic acid	Investigative	45482999	C19H20O4	312.4	CC(=O)OC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B5ZP7Q	3-Acetoxy-5-(biphenyl-4-yl)pentanoic acid	Investigative	45482999	C19H20O4	312.4	CC(=O)OC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B61DLV	[(4-Cyanoanilino)-phosphonomethyl]phosphonic acid	Investigative	72204932	C8H10N2O6P2	292.12	C1=CC(=CC=C1C#N)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B61DLV	[(4-Cyanoanilino)-phosphonomethyl]phosphonic acid	Investigative	72204932	C8H10N2O6P2	292.12	C1=CC(=CC=C1C#N)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B61DLV	[(4-Cyanoanilino)-phosphonomethyl]phosphonic acid	Investigative	72204932	C8H10N2O6P2	292.12	C1=CC(=CC=C1C#N)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B62FNU	(R)-2-(4''-((4-(4-Fluorobenzoyl)phenoxy)methyl)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid	Investigative	11613810	C31H28FNO6S	561.6	CC(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)COC3=CC=C(C=C3)C(=O)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B62HUJ	(E)-2-(5-((5-(4-Methoxyphenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid	Investigative	2140735	C17H13NO5S2	375.4	COC1=CC=C(C=C1)C2=CC=C(O2)/C=C/3\\C(=O)N(C(=S)S3)CC(=O)O	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B65KHL	(2R)-N-[[(4R)-4-Cyclopropyl-2,5-dioxoimidazolidin-4-yl]methyl]-2-methyl-3-[4-(trifluoromethyl)phenyl]propanamide	Investigative	74221194	C18H20F3N3O3	383.4	C[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B65WHM	4-[4-[2-[(3S)-3-Hydroxy-1-azabicyclo[2.2.2]octan-3-yl]ethynyl]phenoxy]-N-methylbenzamide	Investigative	57392969	C23H24N2O3	376.4	CNC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)C#C[C@@]3(CN4CCC3CC4)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B65WHM	4-[4-[2-[(3S)-3-Hydroxy-1-azabicyclo[2.2.2]octan-3-yl]ethynyl]phenoxy]-N-methylbenzamide	Investigative	57392969	C23H24N2O3	376.4	CNC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)C#C[C@@]3(CN4CCC3CC4)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B65WHM	4-[4-[2-[(3S)-3-Hydroxy-1-azabicyclo[2.2.2]octan-3-yl]ethynyl]phenoxy]-N-methylbenzamide	Investigative	57392969	C23H24N2O3	376.4	CNC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)C#C[C@@]3(CN4CCC3CC4)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B68HAL	2-(Benzyl-hydroxycarbamoylmethyl-amino)-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide	Investigative	25178356	C19H24N4O5S	420.5	C1=CC=C(C=C1)CN(CC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B68HAL	2-(Benzyl-hydroxycarbamoylmethyl-amino)-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide	Investigative	25178356	C19H24N4O5S	420.5	C1=CC=C(C=C1)CN(CC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B69FKU	Chembl4208646	Investigative	46840956	C31H22O10	554.5	COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)O)O)O	IC50 = 74340 nM	Poor binder
T80942	Matrix metalloproteinase 2	B69LRQ	(R)-4-(4-Carboxy-2-(3,4,5-trimethoxybenzamido)butanamido)-2-hydroxybenzoic acid	Investigative	44582905	C22H24N2O10	476.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC(=C(C=C2)C(=O)O)O	IC50 = 86300 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6A7YN	(4S,5S)-2-(4-Chloro-phenyl)-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394744	C11H10ClNOS	239.72	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)Cl)S	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6A7YN	(4S,5S)-2-(4-Chloro-phenyl)-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394744	C11H10ClNOS	239.72	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)Cl)S	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6BP5U	N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-N-hydroxy-formamide	Investigative	10907701	C24H26F3NO8S	545.5	C1CC2(CCC1C(CS(=O)(=O)C3=CC=C(C=C3)OC4=CC=C(C=C4)OC(F)(F)F)N(C=O)O)OCCO2	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B6BTQ8	4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole	Investigative	44445275	C13H14N4O	242.28	C1COC(=N1)C2=CN(N=N2)CCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6BTQ8	4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole	Investigative	44445275	C13H14N4O	242.28	C1COC(=N1)C2=CN(N=N2)CCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6BTQ8	4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole	Investigative	44445275	C13H14N4O	242.28	C1COC(=N1)C2=CN(N=N2)CCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6BTQ8	4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole	Investigative	44445275	C13H14N4O	242.28	C1COC(=N1)C2=CN(N=N2)CCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B6BZ7Q	Benzyl 6-mercaptopicolinate	Investigative	44445244	C13H11NO2S	245.3	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 82000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6BZ7Q	Benzyl 6-mercaptopicolinate	Investigative	44445244	C13H11NO2S	245.3	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6BZ7Q	Benzyl 6-mercaptopicolinate	Investigative	44445244	C13H11NO2S	245.3	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 88000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6BZ7Q	Benzyl 6-mercaptopicolinate	Investigative	44445244	C13H11NO2S	245.3	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 101000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B6C3IU	Biphenylsulfonamide carboxylate, 9	Investigative	24901479	C17H19NO4S	333.4	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B6C9GT	2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane	Investigative	9883002	C15H14O3S2	306.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 96000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6C9GT	2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane	Investigative	9883002	C15H14O3S2	306.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 206000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6CAZ2	N-[(2R)-2-Amino-3-phenylpropyl]-3,5-dinitrobenzamide	Investigative	42645753	C16H16N4O5	344.32	C1=CC=C(C=C1)C[C@H](CNC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-])N	IC50 = 100700 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6CO7B	(R)-N-Benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-methyl-1,2,4-oxadiazole-3-carboxamide	Investigative	10180993	C23H32N4O4	428.5	CN(CC1=CC=CC=C1)C(=O)C2=NOC(=N2)[C@H](CCCC3CCCCC3)CC(=O)NO	IC50 = 81800 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6D5XV	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-aminopent-4-enoic acid	Investigative	71465468	C18H20N2O5S	376.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CC=C)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6D5XV	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-aminopent-4-enoic acid	Investigative	71465468	C18H20N2O5S	376.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CC=C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6FYQ5	N6-[(Benzyloxy)carbonyl]-N2-cinnamoyl-L-lysine	Investigative	44586532	C23H26N2O5	410.5	C1=CC=C(C=C1)COC(=O)NCCCC[C@@H](C(=O)O)NC(=O)/C=C/C2=CC=CC=C2	IC50 = 50500 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 = 61000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 = 92000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B6HQO3	(Diethylamino)carbonylphosphonic acid	Investigative	12671872	C5H12NO4P	181.13	CCN(CC)C(=O)P(=O)(O)O	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6HQO3	(Diethylamino)carbonylphosphonic acid	Investigative	12671872	C5H12NO4P	181.13	CCN(CC)C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6HY7C	3-[1-(2-Carboxy-ethylcarbamoyl)-2-cyclohexyl-ethylcarbamoyl]-6-p-tolyl-hexanoic acid	Investigative	44314442	C26H38N2O6	474.6	CC1=CC=C(C=C1)CCC[C@H](CC(=O)O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCC(=O)O	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6IN8S	Sodium hydrogen (butylamino)carbonylphosphonate	Investigative	23692637	C5H11NNaO4P	203.11	CCCCNC(=O)P(=O)(O)[O-].[Na+]	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B6IN8S	Sodium hydrogen (butylamino)carbonylphosphonate	Investigative	23692637	C5H11NNaO4P	203.11	CCCCNC(=O)P(=O)(O)[O-].[Na+]	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6IN8S	Sodium hydrogen (butylamino)carbonylphosphonate	Investigative	23692637	C5H11NNaO4P	203.11	CCCCNC(=O)P(=O)(O)[O-].[Na+]	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B6J1EV	6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445248	C14H13NO2S	259.329	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 81000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6J1EV	6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445248	C14H13NO2S	259.329	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 98000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6J1EV	6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445248	C14H13NO2S	259.329	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 119000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6J1EV	6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445248	C14H13NO2S	259.329	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6L5WX	Berkeleylactone A	Investigative	132967549	C19H32O7S	404.5	C[C@@H]1CCCCCCCCC[C@@H](C(=O)C[C@H](C(=O)O1)SC[C@H](C(=O)O)O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6N5UR	((4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol	Investigative	44394879	C13H15NO2	217.26	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)CO	Ki = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 10	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6P5EB	[(2S)-3-[[(2S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-oxo-2-[2-(trifluoromethoxy)phenyl]sulfanylpropyl]-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphinic acid	Investigative	71451330	C37H36F3N4O7PS	768.7	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(C[C@H](C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N)SC5=CC=CC=C5OC(F)(F)F)O	Ki = 148000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6QZN9	Chembl4214716	Investigative	145971807	C50H52Cl2F2N4O5S	929.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=C(C=C5)F)Cl)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=C(C=C7)F)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B6QZN9	Chembl4214716	Investigative	145971807	C50H52Cl2F2N4O5S	929.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=C(C=C5)F)Cl)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=C(C=C7)F)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6QZN9	Chembl4214716	Investigative	145971807	C50H52Cl2F2N4O5S	929.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=C(C=C5)F)Cl)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=C(C=C7)F)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6RX0F	N-Hydroxy-N-{1-methoxymethyl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	11144824	C18H18F3NO7S	449.4	COCC(CS(=O)(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B6VU7L	(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	56682293	C24H33IN4O3	552.4	CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)I)O)N)N	IC50 = 86600 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6W3HR	Chembl4202989	Investigative	145978450	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 = 58300 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6W3HR	Chembl4202989	Investigative	145978450	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 = 82600 nM	Poor binder
T80942	Matrix metalloproteinase 8	B6W3HR	Chembl4202989	Investigative	145978450	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 = 84000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B6W3RO	N-(4-Amino-2-methylquinolin-6-yl)-2-(4-phenylmethoxyphenoxy)acetamide	Investigative	73055016	C25H23N3O3	413.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)COC3=CC=C(C=C3)OCC4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6W3RO	N-(4-Amino-2-methylquinolin-6-yl)-2-(4-phenylmethoxyphenoxy)acetamide	Investigative	73055016	C25H23N3O3	413.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)COC3=CC=C(C=C3)OCC4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6WC8Y	N-[1-[4-(4-Cyanophenyl)phenoxy]-3-(4-fluorophenyl)propan-2-yl]-N-hydroxyformamide	Investigative	21699983	C23H19FN2O3	390.4	C1=CC(=CC=C1CC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O)F	IC50 = 180000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6XAU1	3-(3,4-Dimethoxyphenyl)-2-[(E)-3-phenylprop-2-enoyl]oxypropanoic acid	Investigative	71654517	C20H20O6	356.4	COC1=C(C=C(C=C1)CC(C(=O)O)OC(=O)/C=C/C2=CC=CC=C2)OC	IC50 = 53700 nM	Poor binder
T80942	Matrix metalloproteinase 3	B6YT2H	(S)-2-((E)-3-Furan-2-yl-acryloylamino)-3-(1H-indol-3-yl)-propionic acid	Investigative	40424573	C18H16N2O4	324.3	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)/C=C/C3=CC=CO3	Ki = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B6Z5OF	3-[2-Cyclohexyl-1-(4-morpholin-4-yl-butylcarbamoyl)-ethylcarbamoyl]-6-p-tolyl-hexanoic acid	Investigative	44314824	C31H49N3O5	543.7	CC1=CC=C(C=C1)CCC[C@H](CC(=O)O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCCCN3CCOCC3	Ki = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B71NZU	[(4S,5S)-2-((Z)-4-Phenyl-buta-1,3-dienyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol	Investigative	44394681	C16H17NO2	255.31	C=C[C@H]1[C@@H](N=C(O1)/C=C\\C=C\\C2=CC=CC=C2)CO	Ki = 153000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B71YOW	N-[1-(4'-Cyano-4-biphenylyloxymethyl)-3-methylbutyl]formhydroxamic acid	Investigative	21700004	C20H22N2O3	338.4	CC(C)CC(COC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)N(C=O)O	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B72TWU	(2S)-2-Amino-3-methyl-N-[(2R)-2-amino-3-phenylpropyl]propionamide	Investigative	44588219	C14H23N3O	249.35	CC(C)[C@@H](C(=O)NC[C@@H](CC1=CC=CC=C1)N)N	IC50 = 151400 nM	Poor binder
T80942	Matrix metalloproteinase 7	B75TPB	5-(2-Hydroxyethyl)-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione	Investigative	9862764	C18H16N2O5	340.3	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3(C(=O)NC(=O)NC3=O)CCO	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B76AGQ	4''-Methylepigallocatechin gallate	Investigative	401129	C23H20O11	472.4	COC1=C(C=C(C=C1O)C(=O)O[C@@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C(=C4)O)O)O)O)O)O	IC50 = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B76AON	4-Phenoxy-N-[(1S,2R)-2-sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682767	C17H19NO3S2	349.5	C1C[C@@H]([C@@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B78GIR	4-Thiouracil	Investigative	2734394	C4H4N2OS	128.15	C1=CNC(=O)NC1=S	IC50 = 121000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7A4ML	5-(4-(Dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypentanoic acid	Investigative	45483022	C23H20O4	360.4	C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)C4=CC=C(C=C4)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B7AQZ3	9-(3,5-Difluorophenyl)-6-(ethylamino)-2-purinecarbonitrile	Investigative	44143091	C14H10F2N6	300.27	CCNC1=C2C(=NC(=N1)C#N)N(C=N2)C3=CC(=CC(=C3)F)F	IC50 = 134896.29 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7G2CJ	(4S,5S)-4-Phenylsulfanyl-2-p-tolyl-5-vinyl-4,5-dihydro-oxazole	Investigative	44394797	C18H17NOS	295.4	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)SC3=CC=CC=C3	Ki = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B7HAY0	Phenethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445205	C14H13NO3	243.26	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=O)N2	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B7HAY0	Phenethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445205	C14H13NO3	243.26	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7HAY0	Phenethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445205	C14H13NO3	243.26	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=O)N2	IC50 = 81000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B7JFU8	N-Butyl-2-[1-[2-(4-fluoro-phenyl)-ethyl]-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328296	C29H33FN4O5	536.6	CCCCN(CC(=O)NO)C(=O)CN(CCC1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7KIW9	N-(4-Amino-2-methylquinolin-6-yl)-4-phenylbenzamide	Investigative	73054735	C23H19N3O	353.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)C4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B7L5OB	4-Bromo-N-hydroxybenzenesulfonamide	Investigative	121255	C6H6BrNO3S	252.09	C1=CC(=CC=C1S(=O)(=O)NO)Br	Ki = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7L5OB	4-Bromo-N-hydroxybenzenesulfonamide	Investigative	121255	C6H6BrNO3S	252.09	C1=CC(=CC=C1S(=O)(=O)NO)Br	Ki = 66000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B7L5OB	4-Bromo-N-hydroxybenzenesulfonamide	Investigative	121255	C6H6BrNO3S	252.09	C1=CC(=CC=C1S(=O)(=O)NO)Br	Ki = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7L5OB	4-Bromo-N-hydroxybenzenesulfonamide	Investigative	121255	C6H6BrNO3S	252.09	C1=CC(=CC=C1S(=O)(=O)NO)Br	Ki = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B7L6VX	Chembl4160618	Investigative	145956426	C11H13N3O7S	331.3	C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)N[C@@H](CCC(=O)N)C(=O)O	IC50 = 76300 nM	Poor binder
T80942	Matrix metalloproteinase 12	B7L6VX	Chembl4160618	Investigative	145956426	C11H13N3O7S	331.3	C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)N[C@@H](CCC(=O)N)C(=O)O	IC50 = 100100 nM	Poor binder
T80942	Matrix metalloproteinase 8	B7L6VX	Chembl4160618	Investigative	145956426	C11H13N3O7S	331.3	C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)N[C@@H](CCC(=O)N)C(=O)O	IC50 = 198900 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7LQ0G	3-Hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid (biphenyl-4-ylmethyl)-amide	Investigative	54687474	C20H17NO4	335.4	CC1=CC(=O)C(=C(O1)C(=O)NCC2=CC=C(C=C2)C3=CC=CC=C3)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7MFT8	(1R,2S,5R)-2-[2-[4-(4-Chlorophenyl)phenyl]ethylsulfonyl]-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	10875332	C28H26ClN3O5S	552	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)S(=O)(=O)CCC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B7PA0B	5-(2-Chloro-6-methyl-phenylamino)-3H-[1,3,4]thiadiazole-2-thione	Investigative	44285343	C9H8ClN3S2	257.8	CC1=C(C(=CC=C1)Cl)NC2=NNC(=S)S2	IC50 = 173000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B7POG6	N-(1-Benzylcarbamoyl-ethyl)-N''-hydroxy-2-isobutyl-malonamide	Investigative	44343258	C17H25N3O4	335.4	CC(C)CC(C(=O)NC(C)C(=O)NCC1=CC=CC=C1)C(=O)NO	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7R6HS	{2-[2-Cyclohexyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-ethylcarbamoyl]-5-phenyl-pentyl}-phosphonic acid	Investigative	44314958	C27H44N3O6P	537.6	C1CCC(CC1)C[C@@H](C(=O)NCCN2CCOCC2)NC(=O)[C@H](CCCC3=CC=CC=C3)CP(=O)(O)O	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B7UZR2	Chembl4212449	Investigative	145964617	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7F	IC50 = 64500 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7UZR2	Chembl4212449	Investigative	145964617	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7F	IC50 = 66600 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7VS2E	3-Phenoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445234	C19H15NO4	321.3	C1=CC=C(C=C1)OC2=CC=CC(=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B7VS2E	3-Phenoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445234	C19H15NO4	321.3	C1=CC=C(C=C1)OC2=CC=CC(=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 118000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7W4AB	N-{[4-(But-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan	Investigative	42627769	C22H22N2O5S	426.5	CC#CCOC1=CC=C(C=C1)S(=O)(=O)N[C@H](CC2=CNC3=C2C=C(C=C3)C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7WNT8	4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445212	C16H17NO4	287.31	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=O)N2	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B7WNT8	4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445212	C16H17NO4	287.31	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=O)N2	IC50 = 82000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B7WNT8	4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445212	C16H17NO4	287.31	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=O)N2	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7WNT8	4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445212	C16H17NO4	287.31	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=O)N2	IC50 = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7Y9SC	(3S,4S)-3-(4-Phenoxybenzenesulfonamido)-4-mercaptopyrrolidine Hydrochloride	Investigative	71680707	C16H19ClN2O3S2	386.9	C1[C@@H]([C@H](CN1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B7Z6GY	1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445271	C11H14N4O	218.26	C1CCC(=CC1)N2C=C(N=N2)C3=NCCO3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B7Z6GY	1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445271	C11H14N4O	218.26	C1CCC(=CC1)N2C=C(N=N2)C3=NCCO3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B7Z6GY	1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445271	C11H14N4O	218.26	C1CCC(=CC1)N2C=C(N=N2)C3=NCCO3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B7Z6GY	1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445271	C11H14N4O	218.26	C1CCC(=CC1)N2C=C(N=N2)C3=NCCO3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B7ZAP0	5-Hydroxy-5-[2-(4-nitrophenyl)-2-oxoethyl]-1,3-diazinane-2,4,6-trione	Investigative	71454740	C12H9N3O7	307.22	C1=CC(=CC=C1C(=O)CC2(C(=O)NC(=O)NC2=O)O)[N+](=O)[O-]	IC50 = 63000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B83QWM	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)propanamide	Investigative	56675664	C18H24N4O3	344.4	C1=CC(=CC=C1C[C@@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)N)O)N)N)O	IC50 = 111300 nM	Poor binder
T80942	Matrix metalloproteinase 14	B83XTH	(2R)-N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]-4-(benzyloxycarbonylamino)butyramide	Investigative	72714322	C25H25Br2N3O7S	671.4	C1=CC=C(C=C1)COC(=O)NCC[C@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)OCC3=CC(=CC(=C3)Br)Br	IC50 = 104000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B86BFX	N-[(Hydroxyamino)carbonyl]-D-leucyl-Lphenylalanine methylamide	Investigative	24881245	C17H26N4O4	350.4	CC(C)C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B86BFX	N-[(Hydroxyamino)carbonyl]-D-leucyl-Lphenylalanine methylamide	Investigative	24881245	C17H26N4O4	350.4	CC(C)C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B86FOU	2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-(4-thiazol-2-yl-phenylsulfanyl)-cyclopentanecarboxylic acid	Investigative	11026991	C23H20N4O3S2	464.6	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)SC4=CC=C(C=C4)C5=NC=CS5	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B86QXD	(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-iodophenyl)propyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	56682295	C24H33IN4O3	552.4	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)I)O)N)NC(=O)[C@@H](CC2=CC=CC=C2)N	IC50 = 52700 nM	Poor binder
T80942	Matrix metalloproteinase 1	B87DNV	(Hydroxyamino)(4-iodophenyl)sulfone	Investigative	5220706	C6H6INO3S	299.09	C1=CC(=CC=C1S(=O)(=O)NO)I	Ki = 66000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B87DNV	(Hydroxyamino)(4-iodophenyl)sulfone	Investigative	5220706	C6H6INO3S	299.09	C1=CC(=CC=C1S(=O)(=O)NO)I	Ki = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B87DNV	(Hydroxyamino)(4-iodophenyl)sulfone	Investigative	5220706	C6H6INO3S	299.09	C1=CC(=CC=C1S(=O)(=O)NO)I	Ki = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B87DNV	(Hydroxyamino)(4-iodophenyl)sulfone	Investigative	5220706	C6H6INO3S	299.09	C1=CC(=CC=C1S(=O)(=O)NO)I	Ki = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B87SHX	N-[[(4S)-4-(1-Methylimidazol-2-yl)-2,5-dioxoimidazolidin-4-yl]methyl]-5-(trifluoromethyl)-1-benzofuran-2-carboxamide	Investigative	101910871	C18H14F3N5O4	421.3	CN1C=CN=C1[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)C(F)(F)F	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B87SHX	N-[[(4S)-4-(1-Methylimidazol-2-yl)-2,5-dioxoimidazolidin-4-yl]methyl]-5-(trifluoromethyl)-1-benzofuran-2-carboxamide	Investigative	101910871	C18H14F3N5O4	421.3	CN1C=CN=C1[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)C(F)(F)F	IC50 = 86000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B89SNP	N-[(E)-Benzylideneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide	Investigative	14616298	C18H16N4O2	320.3	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=CC=CC=C3	IC50 = 67010 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8ARM3	3-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445214	C13H10FNO3	247.22	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=O)N2	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8ARM3	3-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445214	C13H10FNO3	247.22	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=O)N2	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8CUO9	(2R,3R)-4-[2-(3-Chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(4-pyrazol-1-ylphenyl)methyl]butanamide	Investigative	46919610	C24H25ClN4O4	468.9	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCC2=CC=C(C=C2)N3C=CC=N3)O)O)C4=CC(=CC=C4)Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B8DC0N	Cyclooctylcarbamoylphosphonic Acid	Investigative	11817193	C9H18NO4P	235.22	C1CCCC(CCC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8DC0N	Cyclooctylcarbamoylphosphonic Acid	Investigative	11817193	C9H18NO4P	235.22	C1CCCC(CCC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8DC0N	Cyclooctylcarbamoylphosphonic Acid	Investigative	11817193	C9H18NO4P	235.22	C1CCCC(CCC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8H6ZF	6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester	Investigative	44445265	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8H6ZF	6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester	Investigative	44445265	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 119000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B8H6ZF	6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester	Investigative	44445265	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 135000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8H6ZF	6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester	Investigative	44445265	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B8I0RK	Thiadiazole derivative, 35	Investigative	24754252	C24H21N3O2S	415.5	CC1=CC2=C(C=C1)N(C(=O)C23NN=C(S3)C4=CC=C(C=C4)OC)C5=CC=CC=C5C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B8JE1T	3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid	Investigative	4085085	C19H12N2O4S	364.4	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN(C(=S)N3)C4=CC=CC(=C4)C(=O)O	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8JE1T	3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid	Investigative	4085085	C19H12N2O4S	364.4	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN(C(=S)N3)C4=CC=CC(=C4)C(=O)O	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B8JE1T	3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid	Investigative	4085085	C19H12N2O4S	364.4	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN(C(=S)N3)C4=CC=CC(=C4)C(=O)O	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8KZB0	(2S)-2-(Naphthalen-2-ylsulfonylamino)-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide	Investigative	90663062	C24H23N5O4S3	541.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 53000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8KZB0	(2S)-2-(Naphthalen-2-ylsulfonylamino)-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide	Investigative	90663062	C24H23N5O4S3	541.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8OCE9	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-thiopyran-4-ylidenemethyl)-ethyl]-formamide	Investigative	44330132	C26H28N2O5S2	512.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCSCC4)N(C=O)O	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8PY5V	(5Z)-5-[(2,4-Dihydroxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one	Investigative	7028541	C10H8N2O3S	236.25	C1=CC(=C(C=C1O)O)/C=C\\2/C(=O)NC(=S)N2	IC50 = 105900 nM	Poor binder
T80942	Matrix metalloproteinase 13	B8QGP0	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036769	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC=C(C=C4)[N+](=O)[O-])/S3	IC50 = 55880 nM	Poor binder
T80942	Matrix metalloproteinase 3	B8QGP0	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036769	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC=C(C=C4)[N+](=O)[O-])/S3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8QZ0Y	(2S)-2,6-Amino-N-[(2R)-2-amino-3-phenylpropyl]caproylamide	Investigative	42645288	C15H26N4O	278.39	C1=CC=C(C=C1)C[C@H](CNC(=O)[C@H](CCCCN)N)N	IC50 = 99700 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8SPR3	Thioacetic acid S-[(4S,5S)-2-(4-bromo-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester	Investigative	44394668	C13H12BrNO2S	326.21	CC(=O)S[C@H]1[C@@H](OC(=N1)C2=CC=C(C=C2)Br)C=C	Ki = 88000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8SX1O	2-[1-Tert-Butyl-3-(4-phenoxy-phenyl)-ureido]-N-cyclohexylmethyl-N-hydroxycarbamoylmethyl-acetamide	Investigative	44327915	C28H38N4O5	510.6	CC(C)(C)N(CC(=O)N(CC1CCCCC1)CC(=O)NO)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8T3VS	(1S,2R,5S)-2-[4-(4-Chlorophenyl)phenyl]sulfanyl-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	9870269	C26H22ClN3O3S	492	C1C[C@H]([C@@H]([C@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)SC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B8TI3E	Boc-Trp-OSu	Investigative	98767	C20H23N3O6	401.4	CC(C)(C)OC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)ON3C(=O)CCC3=O	Ki = 84000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8U0SC	2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445222	C13H10ClNO3	263.67	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Cl	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B8U0SC	2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445222	C13H10ClNO3	263.67	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Cl	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B8U0SC	2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445222	C13H10ClNO3	263.67	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Cl	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B8U0SC	2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445222	C13H10ClNO3	263.67	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Cl	IC50 = 81000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B8ZWO6	(2R,3R)-4-(2-(3-Chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide	Investigative	11697504	C20H23ClN2O4S	422.9	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCCC2=CC=CS2)O)O)C3=CC(=CC=C3)Cl	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	B8ZWO6	(2R,3R)-4-(2-(3-Chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide	Investigative	11697504	C20H23ClN2O4S	422.9	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCCC2=CC=CS2)O)O)C3=CC(=CC=C3)Cl	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B8ZWO6	(2R,3R)-4-(2-(3-Chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide	Investigative	11697504	C20H23ClN2O4S	422.9	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCCC2=CC=CS2)O)O)C3=CC(=CC=C3)Cl	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B91PLB	1,10-Phenanthroline	Investigative	1318	C12H8N2	180.2	C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B93YZI	1-(2-Hydroxycarbamoyl-4-methyl-pentanoyl)-pyrrolidine-2-carboxylic acid benzylamide	Investigative	44343397	C19H27N3O4	361.4	CC(C)CC(C(=O)NO)C(=O)N1CCCC1C(=O)NCC2=CC=CC=C2	Ki = 168000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B95JGO	(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(methylamino)-5-oxopentanoic acid	Investigative	44582686	C17H22N2O6	350.4	CNC(=O)[C@H](CCC(=O)O)NC(=O)/C=C/C1=CC(=C(C=C1)OC)OC	IC50 = 159100 nM	Poor binder
T80942	Matrix metalloproteinase 2	B95QFN	2-Cinnamamido-N1-hydroxy-N4-isopropylsuccinamide	Investigative	46228266	C16H21N3O4	319.36	CC(C)NC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 166600 nM	Poor binder
T80942	Matrix metalloproteinase 12	B95ZRL	4-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445215	C13H10FNO3	247.22	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B95ZRL	4-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445215	C13H10FNO3	247.22	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B96EBG	Carbobenzoxyphenylalanine	Investigative	70878	C17H17NO4	299.32	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)OCC2=CC=CC=C2	Ki = 83000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B97DPI	(2R,3R)-4-[(2R)-2-(3-Chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide	Investigative	46856241	C25H27ClN4O4	483	C[C@H](C1=CC=C(C=C1)N2C=CC=N2)NC(=O)[C@@H]([C@H](C(=O)N3CCC[C@@H]3C4=CC(=CC=C4)Cl)O)O	Ki = 88400 nM	Poor binder
T80942	Matrix metalloproteinase 1	B97DPI	(2R,3R)-4-[(2R)-2-(3-Chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamide	Investigative	46856241	C25H27ClN4O4	483	C[C@H](C1=CC=C(C=C1)N2C=CC=N2)NC(=O)[C@@H]([C@H](C(=O)N3CCC[C@@H]3C4=CC(=CC=C4)Cl)O)O	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B98CLB	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-3-ylbenzamide	Investigative	73055907	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CC5=CC=CC=C5N=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B9AEC0	[(4-Phenoxyanilino)-phosphonomethyl]phosphonic acid	Investigative	72205113	C13H15NO7P2	359.21	C1=CC=C(C=C1)OC2=CC=C(C=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	B9DW4I	[(4S,5S)-2-(4-Nitro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol	Investigative	44394886	C12H12N2O4	248.23	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)[N+](=O)[O-])CO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B9DW4I	[(4S,5S)-2-(4-Nitro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol	Investigative	44394886	C12H12N2O4	248.23	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)[N+](=O)[O-])CO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B9FEA2	Furan-2-carboxamide deriv., 18	Investigative	44236904	C26H28N2O4	432.5	CNC(=O)[C@H](C1CCCCC1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)OC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B9GXZ2	(1R,2S,5R)-2-[2-[4-(4-Chlorophenyl)phenyl]ethylsulfanyl]-5-[(1,3-dioxoisoindol-2-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	9892876	C29H26ClNO4S	520	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3C2=O)C(=O)O)SCCC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	B9JL6Z	4-[[6-(3-Morpholin-4-ylprop-1-ynyl)-4-oxoquinazolin-3-yl]methyl]benzoic acid	Investigative	22712799	C23H21N3O4	403.4	C1COCCN1CC#CC2=CC3=C(C=C2)N=CN(C3=O)CC4=CC=C(C=C4)C(=O)O	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B9KGM5	5-Chloro-N-[[(4S)-4-(2-methylpyrazol-3-yl)-2,5-dioxoimidazolidin-4-yl]methyl]-1-benzofuran-2-carboxamide	Investigative	118722688	C17H14ClN5O4	387.8	CN1C(=CC=N1)[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)Cl	IC50 = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B9MBK4	3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-(4-methoxy-phenyl)-hexanoic acid	Investigative	44314969	C31H43N3O7S	601.8	COC1=CC=C(C=C1)CCC[C@H](CC(=O)O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCC3=CC=C(C=C3)S(=O)(=O)N	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	B9MR1L	(R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamoyl)-nonadecanoic acid	Investigative	10394828	C30H50N2O4	502.7	CCCCCCCCCCCCCCCC[C@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B9O2AL	(S,E)-5-(3-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582647	C22H23ClN2O6	446.9	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC(=CC=C2)Cl)OC	IC50 = 120800 nM	Poor binder
T80942	Matrix metalloproteinase 2	B9Q2PE	(Dibutylamino)carbonylphosphonic acid	Investigative	11207122	C9H20NO4P	237.23	CCCCN(CCCC)C(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B9Q2PE	(Dibutylamino)carbonylphosphonic acid	Investigative	11207122	C9H20NO4P	237.23	CCCCN(CCCC)C(=O)P(=O)(O)O	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 8	B9Q2PE	(Dibutylamino)carbonylphosphonic acid	Investigative	11207122	C9H20NO4P	237.23	CCCCN(CCCC)C(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 9	B9Q2PE	(Dibutylamino)carbonylphosphonic acid	Investigative	11207122	C9H20NO4P	237.23	CCCCN(CCCC)C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B9RCW3	Prop-2-enyl 3-(3,4-dimethoxyphenyl)-2-[(E)-3-(4-phenylmethoxyphenyl)prop-2-enoyl]oxypropanoate	Investigative	71654357	C30H30O7	502.6	COC1=C(C=C(C=C1)CC(C(=O)OCC=C)OC(=O)/C=C/C2=CC=C(C=C2)OCC3=CC=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	B9SDM3	(2R)-2-[[4-[4-[(3-Methyl-1-benzofuran-2-yl)methoxy]phenyl]phenyl]sulfonylamino]-3-phenylpropanoic acid	Investigative	44406452	C31H27NO6S	541.6	CC1=C(OC2=CC=CC=C12)COC3=CC=C(C=C3)C4=CC=C(C=C4)S(=O)(=O)N[C@H](CC5=CC=CC=C5)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B9UIW0	[Pentyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid	Investigative	44328246	C31H38N4O5	546.7	CCCCCN(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	B9ZI8U	(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	56661759	C24H33N5O5	471.5	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)[N+](=O)[O-])O)N)NC(=O)[C@@H](CC2=CC=CC=C2)N	IC50 = 105600 nM	Poor binder
T80942	Matrix metalloproteinase 9	BA39YM	Phenethyl 6-mercaptopicolinate	Investigative	44445245	C14H13NO2S	259.329	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=S)N2	IC50 = 107000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BA39YM	Phenethyl 6-mercaptopicolinate	Investigative	44445245	C14H13NO2S	259.329	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=S)N2	IC50 = 117000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BA39YM	Phenethyl 6-mercaptopicolinate	Investigative	44445245	C14H13NO2S	259.329	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=S)N2	IC50 = 119000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BA39YM	Phenethyl 6-mercaptopicolinate	Investigative	44445245	C14H13NO2S	259.329	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=S)N2	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BA3M4C	N-[(Hydroxyamino)carbonyl]-L-leucyl-Lphenylalanine methylamide	Investigative	24881246	C17H26N4O4	350.4	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BA3M4C	N-[(Hydroxyamino)carbonyl]-L-leucyl-Lphenylalanine methylamide	Investigative	24881246	C17H26N4O4	350.4	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BA86TN	5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one	Investigative	12443210	C22H22O12	478.4	COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BA87EI	Methyl (2S)-2-benzamido-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71458326	C25H25NO4	403.5	COC(=O)[C@H](CC1=CC=C(C=C1)OCCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	IC50 = 74600 nM	Poor binder
T80942	Matrix metalloproteinase 1	BA8KI4	4-(4-(Thiiran-2-ylmethylsulfonyl)phenoxy)phenyl methanesulfonate	Investigative	15941677	C16H16O6S3	400.5	CS(=O)(=O)OC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)CC3CS3	Ki = 140000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BA9D7M	(2R)-3-(1-Benzothiophen-3-yl)-2-[[5-[2-(4-butylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]-N-hydroxypropanamide	Investigative	53329216	C27H26N2O4S3	538.7	CCCCC1=CC=C(C=C1)C#CC2=CC=C(S2)S(=O)(=O)N[C@H](CC3=CSC4=CC=CC=C43)C(=O)NO	IC50 = 56000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BAFC17	Dipotassium;6-amino-2-[[2-[4-[3-(carboxylatomethylamino)-2-[[(2S,3S)-2-[[ethoxy(hydroxy)phosphoryl]amino]-3-methylpentanoyl]amino]-3-oxopropyl]phenoxy]acetyl]amino]hexanoate	Investigative	54584143	C27H42K2N5O11P	721.8	CC[C@H](C)[C@@H](C(=O)NC(CC1=CC=C(C=C1)OCC(=O)NC(CCCCN)C(=O)[O-])C(=O)NCC(=O)[O-])NP(=O)(O)OCC.[K+].[K+]	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 148000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BAJF80	Hydroxysulfonamide 50	Investigative	23645540	C8H2F17NO3S	515.15	C(C(C(C(C(F)(F)S(=O)(=O)NO)(F)F)(F)F)(F)F)(C(C(C(F)(F)F)(F)F)(F)F)(F)F	Ki = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BAN7Z4	(Cycloheptylamino)carbonylphosphonic acid	Investigative	11447356	C8H16NO4P	221.19	C1CCCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BAN7Z4	(Cycloheptylamino)carbonylphosphonic acid	Investigative	11447356	C8H16NO4P	221.19	C1CCCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BAN7Z4	(Cycloheptylamino)carbonylphosphonic acid	Investigative	11447356	C8H16NO4P	221.19	C1CCCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BAN7Z4	(Cycloheptylamino)carbonylphosphonic acid	Investigative	11447356	C8H16NO4P	221.19	C1CCCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BAXE23	[[4-(4-Bromophenoxy)anilino]-phosphonomethyl]phosphonic acid	Investigative	72205115	C13H14BrNO7P2	438.1	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)OC2=CC=C(C=C2)Br	IC50 = 87000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BAXL35	N-[1-(4'-Cyano-4-biphenylyloxymethyl)-2-(2,5-dioxo-3,4,4-trimethylimidazolidine-1-yl)ethyl]formhydroxamic acid	Investigative	9932731	C23H24N4O5	436.5	CC1(C(=O)N(C(=O)N1C)CC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O)C	IC50 = 58000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BB5R1E	(R)-5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-isopropyl-1,2,4-oxadiazole-3-carboxamide	Investigative	9947332	C18H30N4O4	366.5	CC(C)NC(=O)C1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BB5SG2	(5S)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2R)-1-[(2S)-2-[[(6R)-6-[(4-hydroxyphenyl)methyl]-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-naphthalen-2-ylpropan-2-yl]piperazine-2,3-dione	Investigative	122181997	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@@H](CC2=CC3=CC=CC=C3C=C2)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O)CN9[C@@H](CNC(=O)C9=O)CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BB5SG2	(5S)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2R)-1-[(2S)-2-[[(6R)-6-[(4-hydroxyphenyl)methyl]-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-naphthalen-2-ylpropan-2-yl]piperazine-2,3-dione	Investigative	122181997	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@@H](CC2=CC3=CC=CC=C3C=C2)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O)CN9[C@@H](CNC(=O)C9=O)CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BB5Y2L	4-(3,5-Dibromo-4-(3-phenylpropyl)-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485476	C19H17Br2N5	475.2	C1=CC=C(C=C1)CCCC2=C(NC(=C2Br)C3=NC=CC4=C3N=C(N4)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BB68WX	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-8-ylbenzamide	Investigative	73056181	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CC=CC5=C4N=CC=C5)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BB68WX	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-8-ylbenzamide	Investigative	73056181	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CC=CC5=C4N=CC=C5)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BB6HM7	(4S)-5-Amino-5-oxo-4-[[(2S)-2-[3-(4-phenylphenyl)propanoylamino]butanoyl]amino]pentanoic acid	Investigative	71109175	C24H29N3O5	439.5	CC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N)NC(=O)CCC1=CC=C(C=C1)C2=CC=CC=C2	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BB9JA3	But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445202	C10H9NO3	191.18	CC#CCOC(=O)C1=CC=CC(=O)N1	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BB9JA3	But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445202	C10H9NO3	191.18	CC#CCOC(=O)C1=CC=CC(=O)N1	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BB9JA3	But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445202	C10H9NO3	191.18	CC#CCOC(=O)C1=CC=CC(=O)N1	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BB9JA3	But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445202	C10H9NO3	191.18	CC#CCOC(=O)C1=CC=CC(=O)N1	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BB9P3G	4-(3,5-Dibromo-4-(3-(trifluoromethyl)phenethyl)-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485460	C19H14Br2F3N5	529.2	C1=CC(=CC(=C1)C(F)(F)F)CCC2=C(NC(=C2Br)C3=NC=CC4=C3N=C(N4)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BBC3H8	4-(4-Bromo-5-methyl-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485485	C11H10BrN5	292.13	CC1=C(C=C(N1)C2=NC=CC3=C2N=C(N3)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BBF3R4	(Cyclopropylamino)carbonylphosphonic acid	Investigative	11252195	C4H8NO4P	165.08	C1CC1NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BBF3R4	(Cyclopropylamino)carbonylphosphonic acid	Investigative	11252195	C4H8NO4P	165.08	C1CC1NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BBF3R4	(Cyclopropylamino)carbonylphosphonic acid	Investigative	11252195	C4H8NO4P	165.08	C1CC1NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 10	BBGK09	2-(2,5-Dimethoxy-phenyl)-isothiazolo[5,4-b]pyridin-3-one	Investigative	11778852	C14H12N2O3S	288.32	COC1=CC(=C(C=C1)OC)N2C(=O)C3=C(S2)N=CC=C3	IC50 = 53000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BBM0L7	(3-Bromophenylamino)Methylenediphosphonic Acid	Investigative	5277481	C7H10BrNO6P2	346.01	C1=CC(=CC(=C1)Br)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BBM0L7	(3-Bromophenylamino)Methylenediphosphonic Acid	Investigative	5277481	C7H10BrNO6P2	346.01	C1=CC(=CC(=C1)Br)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BBM0L7	(3-Bromophenylamino)Methylenediphosphonic Acid	Investigative	5277481	C7H10BrNO6P2	346.01	C1=CC(=CC(=C1)Br)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BBNA52	(2S,3S,4R)-4-(4,5-Dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-8,10-bis(dimethylamino)-2,5,7-trihydroxy-3-methoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione	Investigative	44326171	C31H38N2O12	630.6	CC1C(C(C(C(O1)O[C@H]2[C@@H]([C@](C(=O)C3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C(=CC(=C5O)N(C)C)N(C)C)(C)O)OC)OC)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BBV2R3	N6-[(Benzyloxy)carbonyl]-N2-(2,4-dichlorobenzoyl)-N1-hydroxy-L-lysinamide	Investigative	25022465	C21H23Cl2N3O5	468.3	C1=CC=C(C=C1)COC(=O)NCCCC[C@@H](C(=O)NO)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 = 170000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BBX76W	alpha-Arylsulfonylamino hydroxamate 3S	Investigative	10741133	C17H19BrN2O4S	427.3	CC(C)[C@@H](C(=O)NO)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)Br	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BBX76W	alpha-Arylsulfonylamino hydroxamate 3S	Investigative	10741133	C17H19BrN2O4S	427.3	CC(C)[C@@H](C(=O)NO)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)Br	IC50 = 84000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BBY86P	Benzenemethanesulfonamide, N-hydroxy-	Investigative	23645541	C7H9NO3S	187.22	C1=CC=C(C=C1)CS(=O)(=O)NO	Ki = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BBY86P	Benzenemethanesulfonamide, N-hydroxy-	Investigative	23645541	C7H9NO3S	187.22	C1=CC=C(C=C1)CS(=O)(=O)NO	Ki = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BBY86P	Benzenemethanesulfonamide, N-hydroxy-	Investigative	23645541	C7H9NO3S	187.22	C1=CC=C(C=C1)CS(=O)(=O)NO	Ki = 83000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BBY86P	Benzenemethanesulfonamide, N-hydroxy-	Investigative	23645541	C7H9NO3S	187.22	C1=CC=C(C=C1)CS(=O)(=O)NO	Ki = 95000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BC0GY1	N-Hydroxy-N-{1-(1-methyl-1H-indol-2-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	11092701	C25H21F3N2O6S	534.5	CN1C2=CC=CC=C2C=C1C(CS(=O)(=O)C3=CC=C(C=C3)OC4=CC=C(C=C4)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BC10VU	(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	56665195	C24H33N5O5	471.5	CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N	IC50 = 173100 nM	Poor binder
T80942	Matrix metalloproteinase 14	BC2DS7	(5S)-5-[[4-[5-[(3-Ethyl-1,2-oxazol-5-yl)methoxy]pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-5-methylimidazolidine-2,4-dione	Investigative	73349097	C19H25N7O6S	479.5	CCC1=NOC(=C1)COC2=CN=C(N=C2)N3CCN(CC3)S(=O)(=O)C[C@@]4(C(=O)NC(=O)N4)C	IC50 = 98907 nM	Poor binder
T80942	Matrix metalloproteinase 2	BC2KM9	Benzyl-3-(2-((S)-3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoate	Investigative	49863563	C26H30N4O6	494.5	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@@H](CC2=CC=CC=C2)N)CC(=O)NCCC(=O)OCC3=CC=CC=C3	IC50 = 127000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BC36TM	Cyclobutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445200	C10H11NO3	193.2	C1CC(C1)OC(=O)C2=CC=CC(=O)N2	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BC36TM	Cyclobutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445200	C10H11NO3	193.2	C1CC(C1)OC(=O)C2=CC=CC(=O)N2	IC50 = 62000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BC36TM	Cyclobutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445200	C10H11NO3	193.2	C1CC(C1)OC(=O)C2=CC=CC(=O)N2	IC50 = 66000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BC4Q3O	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036783	C18H13N3O3S2	383.4	COC1=C(C=CC(=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BC6KT9	(4S)-5-[[(2S)-1-Amino-3-carboxy-1-oxopropan-2-yl]amino]-5-oxo-4-[3-[4-(4-phenylthiophen-2-yl)phenyl]propanoylamino]pentanoic acid	Investigative	69922083	C28H29N3O7S	551.6	C1=CC=C(C=C1)C2=CSC(=C2)C3=CC=C(C=C3)CCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BC6KT9	(4S)-5-[[(2S)-1-Amino-3-carboxy-1-oxopropan-2-yl]amino]-5-oxo-4-[3-[4-(4-phenylthiophen-2-yl)phenyl]propanoylamino]pentanoic acid	Investigative	69922083	C28H29N3O7S	551.6	C1=CC=C(C=C1)C2=CSC(=C2)C3=CC=C(C=C3)CCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 61000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 77000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 114000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BC8RU5	(R)-5-(4-Chloro-2-fluorobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582550	C22H24ClFN2O7	482.9	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NCC2=C(C=C(C=C2)Cl)F	IC50 = 52800 nM	Poor binder
T80942	Matrix metalloproteinase 2	BCE62Z	(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine	Investigative	6882342	C24H21N3O2S	415.5	COC1=C(C=C(C=C1)C2=CSC(=NC3=CC=CC=C3)N2/N=C/C4=CC=CC=C4)OC	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BCE62Z	(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine	Investigative	6882342	C24H21N3O2S	415.5	COC1=C(C=C(C=C1)C2=CSC(=NC3=CC=CC=C3)N2/N=C/C4=CC=CC=C4)OC	IC50 = 140000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BCE62Z	(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine	Investigative	6882342	C24H21N3O2S	415.5	COC1=C(C=C(C=C1)C2=CSC(=NC3=CC=CC=C3)N2/N=C/C4=CC=CC=C4)OC	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BCIL03	(Hydroxysulfamoyl)dimethylamine	Investigative	12447203	C2H8N2O3S	140.16	CN(C)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BCIL03	(Hydroxysulfamoyl)dimethylamine	Investigative	12447203	C2H8N2O3S	140.16	CN(C)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BCIL03	(Hydroxysulfamoyl)dimethylamine	Investigative	12447203	C2H8N2O3S	140.16	CN(C)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BCIL03	(Hydroxysulfamoyl)dimethylamine	Investigative	12447203	C2H8N2O3S	140.16	CN(C)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BCJL25	(2R)-2-Amino-N-[(3S)-1-[2-[[2-(hydroxyamino)-2-oxoethyl]amino]-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863622	C18H23N5O6	405.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@@H](CC2=CC=CC=C2)N)CC(=O)NCC(=O)NO	IC50 = 141000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BCK62U	(2S)-N-Hydroxy-5-oxo-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxamide	Investigative	57393179	C18H18N2O3	310.3	C1CC(=O)N([C@@H]1C(=O)NO)CC2=CC=C(C=C2)C3=CC=CC=C3	IC50 = 144000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BCL65G	3-Methyl-2-oxo-quinoxaline-1(2h)-acetohydrazide	Investigative	14616290	C11H12N4O2	232.24	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NN	IC50 = 98020 nM	Poor binder
T80942	Matrix metalloproteinase 1	BCLT94	N-[(2S,4S)-1-[4-[2-(4,6-Dimethylpyridin-3-yl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide	Investigative	53322879	C25H36FN5O4S	521.6	CC1=CC(=NC=C1CCC2CCN(CC2)S(=O)(=O)C[C@](C)(C[C@H](C)C3=NC=C(C=N3)F)N(C=O)O)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BCUY95	(R)-2-(4''-((4-(Cyclohexanecarbonyl)phenoxy)methyl)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid	Investigative	11526826	C31H35NO6S	549.7	CC(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)COC3=CC=C(C=C3)C(=O)C4CCCCC4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BCV7J5	(2S)-2-(Naphthalen-1-ylsulfonylamino)-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide	Investigative	90663070	C24H23N5O4S3	541.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)C3=CC=CC4=CC=CC=C43	Ki = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BCZ94T	2-[(E)-3-(2,3-Dihydro-1-benzofuran-6-yl)prop-2-enoyl]oxy-3-(3,4-dimethoxyphenyl)propanoic acid	Investigative	71652363	C22H22O7	398.4	COC1=C(C=C(C=C1)CC(C(=O)O)OC(=O)/C=C/C2=CC3=C(CCO3)C=C2)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BD1RQ4	Chembl4206821	Investigative	145978127	C35H42N2O5S	602.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5)C)S(=O)(=O)O	IC50 = 89300 nM	Poor binder
T80942	Matrix metalloproteinase 9	BD1RQ4	Chembl4206821	Investigative	145978127	C35H42N2O5S	602.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5)C)S(=O)(=O)O	IC50 = 95900 nM	Poor binder
T80942	Matrix metalloproteinase 9	BD1S0Y	N-(4-Amino-2-methylquinolin-6-yl)-5-methoxy-1H-indole-2-carboxamide	Investigative	73054734	C20H18N4O2	346.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC4=C(N3)C=CC(=C4)OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BD1Z9M	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylidenemethyl)-ethyl]-formamide	Investigative	44330163	C27H28N2O6S	508.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCC(=O)CC4)N(C=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BD20NB	2-[[4-[(3,5-Dibromophenyl)methoxy]phenyl]sulfonylamino]acetic acid	Investigative	72714084	C15H13Br2NO5S	479.1	C1=CC(=CC=C1OCC2=CC(=CC(=C2)Br)Br)S(=O)(=O)NCC(=O)O	IC50 = 125000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BD2V9Y	N-(Carboxymethyl)-N-(3-Phenylpropyl)glycyl-N-Methyl-L-Histidinamide	Investigative	54589400	C20H27N5O4	401.5	CNC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CCCC2=CC=CC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BD2V9Y	N-(Carboxymethyl)-N-(3-Phenylpropyl)glycyl-N-Methyl-L-Histidinamide	Investigative	54589400	C20H27N5O4	401.5	CNC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CCCC2=CC=CC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BD2WO1	N-Tert-Butyl-N-hydroxycarbamoylmethyl-2-[1-isopropyl-3-(4-phenoxy-phenyl)-ureido]-acetamide	Investigative	44327960	C24H32N4O5	456.5	CC(C)N(CC(=O)N(CC(=O)NO)C(C)(C)C)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 155000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BD36TG	Chembl4203061	Investigative	145977013	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)F	IC50 = 59700 nM	Poor binder
T80942	Matrix metalloproteinase 8	BD36TG	Chembl4203061	Investigative	145977013	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)F	IC50 = 92100 nM	Poor binder
T80942	Matrix metalloproteinase 9	BD36TG	Chembl4203061	Investigative	145977013	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BD3KM6	4-[[4-Oxo-6-(3-phenylpropa-1,2-dienyl)quinazolin-3-yl]methyl]benzoic acid	Investigative	22482219	C25H18N2O3	394.4	C1=CC=C(C=C1)C=C=CC2=CC3=C(C=C2)N=CN(C3=O)CC4=CC=C(C=C4)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BD57BI	Chembl4211700	Investigative	145963891	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 = 52800 nM	Poor binder
T80942	Matrix metalloproteinase 8	BD57BI	Chembl4211700	Investigative	145963891	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 = 90200 nM	Poor binder
T80942	Matrix metalloproteinase 9	BD57BI	Chembl4211700	Investigative	145963891	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BD85MN	(5Z)-5-[4-(Benzyloxy)benzylidene]-2-thioxo-1,3-thiazolidin-4-one	Investigative	1204907	C17H13NO2S2	327.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C\\3/C(=O)NC(=S)S3	IC50 = 77430 nM	Poor binder
T80942	Matrix metalloproteinase 9	BDE1Y7	3-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	24755074	C13H10ClNO3	263.67	C1=CC(=CC(=C1)Cl)COC(=O)C2=CC=CC(=O)N2	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BDJ0T9	(R)-5-(3-Iodobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582549	C22H25IN2O7	556.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NCC2=CC(=CC=C2)I	IC50 = 76800 nM	Poor binder
T80942	Matrix metalloproteinase 12	BDJ7N6	4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole	Investigative	44445276	C14H16N4O	256.3	C1COC(=N1)C2=CN(N=N2)CCCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BDJ7N6	4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole	Investigative	44445276	C14H16N4O	256.3	C1COC(=N1)C2=CN(N=N2)CCCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BDJ7N6	4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole	Investigative	44445276	C14H16N4O	256.3	C1COC(=N1)C2=CN(N=N2)CCCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BDJ7N6	4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole	Investigative	44445276	C14H16N4O	256.3	C1COC(=N1)C2=CN(N=N2)CCCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BDO0J3	5-(4-(9H-Fluoren-2-yl)phenyl)-3-hydroxypentanoic acid	Investigative	45483016	C24H22O3	358.4	C1C2=CC=CC=C2C3=C1C=C(C=C3)C4=CC=C(C=C4)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BDP5Z6	Chembl4211258	Investigative	145966420	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)OC	IC50 = 76500 nM	Poor binder
T80942	Matrix metalloproteinase 9	BDP5Z6	Chembl4211258	Investigative	145966420	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)OC	IC50 = 83400 nM	Poor binder
T80942	Matrix metalloproteinase 13	BDW32Q	4-(Benzyloxy)-N-(4-pyridinylmethyl)benzamide	Investigative	2994402	C20H18N2O2	318.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BDX1T5	(S)-2-Tert-Butoxycarbonylamino-3-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-propionic acid	Investigative	13875965	C25H30N2O6S	486.6	CC1=CC(=C(C(=C1)C)S(=O)(=O)N2C=C(C3=CC=CC=C32)C[C@@H](C(=O)O)NC(=O)OC(C)(C)C)C	Ki = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BDX8N2	[4-(Trifluoromethyl)phenyl]methyl 6-oxo-1H-pyridine-2-carboxylate	Investigative	46905989	C14H10F3NO3	297.23	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BDX8N2	[4-(Trifluoromethyl)phenyl]methyl 6-oxo-1H-pyridine-2-carboxylate	Investigative	46905989	C14H10F3NO3	297.23	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 101000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BDX8N2	[4-(Trifluoromethyl)phenyl]methyl 6-oxo-1H-pyridine-2-carboxylate	Investigative	46905989	C14H10F3NO3	297.23	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 112000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BDXN08	Cyclohexylmethylcarbamoylphosphonic Acid	Investigative	11470070	C8H16NO4P	221.19	C1CCC(CC1)CNC(=O)P(=O)(O)O	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BDY8G1	Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-(4-phenylmethoxyphenyl)propanoate	Investigative	71452971	C25H25NO4	403.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=CC=CC=C3)C(=O)OC	IC50 = 83700 nM	Poor binder
T80942	Matrix metalloproteinase 3	BE06IA	Chembl4282646	Investigative	132967554	C16H28O5	300.39	C[C@@H]1[C@H](CCCCCCCC[C@@H]([C@@H](/C=C/C(=O)O1)O)O)O	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BE0RB9	(4S,5S)-4-Phenylsulfanyl-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazole	Investigative	44394594	C19H17NOS	307.4	C=C[C@H]1[C@@H](N=C(O1)/C=C/C2=CC=CC=C2)SC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BE0RB9	(4S,5S)-4-Phenylsulfanyl-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazole	Investigative	44394594	C19H17NOS	307.4	C=C[C@H]1[C@@H](N=C(O1)/C=C/C2=CC=CC=C2)SC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BE0ZB9	6-Mercapto-pyridine-2-carboxylic acid 3-methyl-benzyl ester	Investigative	44445247	C14H13NO2S	259.329	CC1=CC(=CC=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BE0ZB9	6-Mercapto-pyridine-2-carboxylic acid 3-methyl-benzyl ester	Investigative	44445247	C14H13NO2S	259.329	CC1=CC(=CC=C1)COC(=O)C2=CC=CC(=S)N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BE2AB4	N-Heptyl-N-hydroxycarbamoylmethyl-2-[1-pentyl-3-(4-phenoxy-phenyl)-ureido]-acetamide	Investigative	44327916	C29H42N4O5	526.7	CCCCCCCN(CC(=O)NO)C(=O)CN(CCCCC)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BE46JH	2-[(4-But-2-ynoxyphenyl)sulfonylamino]-3-(5-methoxy-1H-indol-3-yl)propanoic Acid	Investigative	11510523	C22H22N2O6S	442.5	CC#CCOC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CNC3=C2C=C(C=C3)OC)C(=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BE53SW	N-Hydroxy-2-nitrobenzene-1-sulfonamide	Investigative	23645544	C6H6N2O5S	218.19	C1=CC=C(C(=C1)[N+](=O)[O-])S(=O)(=O)NO	Ki = 59000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BE56OY	Furan-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445239	C10H7NO4	205.17	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CO2	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BE56OY	Furan-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445239	C10H7NO4	205.17	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CO2	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BE56OY	Furan-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445239	C10H7NO4	205.17	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CO2	IC50 = 111000 nM	Poor binder
T80942	Matrix metalloproteinase 10	BE5TD1	2-(2,4-Dimethoxy-phenyl)-isothiazolo[5,4-b]pyridin-3-one	Investigative	10016964	C14H12N2O3S	288.32	COC1=CC(=C(C=C1)N2C(=O)C3=C(S2)N=CC=C3)OC	IC50 = 62000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BE89GB	(R)-5-(4-Bromophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582888	C21H23BrN2O7	495.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Br	IC50 = 54400 nM	Poor binder
T80942	Matrix metalloproteinase 1	BE93AF	N-{1-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-N-hydroxy-formamide	Investigative	44314349	C22H24F3NO8S	519.5	CC1(OCC(O1)C[C@@H](CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BE94AJ	4-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445223	C13H10ClNO3	263.67	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BE94AJ	4-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445223	C13H10ClNO3	263.67	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BE9WV7	N-Hydroxy-2-[[4-[(4-phenylphenyl)methoxy]phenyl]sulfonylamino]acetamide	Investigative	72713863	C21H20N2O5S	412.5	C1=CC=C(C=C1)C2=CC=C(C=C2)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO	IC50 = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BED10O	(2S)-2-[[2-(3-Methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenyl-N-propylpropanamide	Investigative	46232418	C23H26N4O3	406.5	CCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN2C3=CC=CC=C3N=C(C2=O)C	IC50 = 56600 nM	Poor binder
T80942	Matrix metalloproteinase 2	BEPO61	(S)-Benzyl-2-(2-((S)-3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)-4-methylpentanoate	Investigative	49863562	C29H36N4O6	536.6	CC(C)C[C@@H](C(=O)OCC1=CC=CC=C1)NC(=O)CN2C(=O)CC[C@@H](C2=O)NC(=O)[C@H](CC3=CC=CC=C3)N	IC50 = 121000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BEUF79	(2R)-N-Hydroxy-4-methyl-2-[[methyl(phenyl)phosphoryl]amino]pentanamide	Investigative	10541018	C13H21N2O3P	284.29	CC(C)C[C@H](C(=O)NO)N[P@](=O)(C)C1=CC=CC=C1	IC50 = 130500 nM	Poor binder
T80942	Matrix metalloproteinase 1	BEUF79	(2R)-N-Hydroxy-4-methyl-2-[[methyl(phenyl)phosphoryl]amino]pentanamide	Investigative	10541018	C13H21N2O3P	284.29	CC(C)C[C@H](C(=O)NO)N[P@](=O)(C)C1=CC=CC=C1	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BEW6D2	2,4,5-Trifluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445220	C13H8F3NO3	283.2	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 56000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BEW6D2	2,4,5-Trifluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445220	C13H8F3NO3	283.2	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BEW6D2	2,4,5-Trifluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445220	C13H8F3NO3	283.2	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 86000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BF09QZ	(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(3-(4-fluorophenyl)-1-methoxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44582746	C26H29FN2O8	516.5	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC(CC2=CC=C(C=C2)F)C(=O)OC)OC	IC50 = 76500 nM	Poor binder
T80942	Matrix metalloproteinase 14	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BF0HQ4	Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445235	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CS2	IC50 = 56000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BF0HQ4	Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445235	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CS2	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF0HQ4	Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445235	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CS2	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BF0HQ4	Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445235	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CS2	IC50 = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BF12NZ	4-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445268	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 93000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BF12NZ	4-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445268	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 109000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF12NZ	4-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445268	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BF12NZ	4-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445268	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 114000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BF26XN	N-Hydroxy-N-[2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-1-(4-trifluoromethyl-phenyl)-ethyl]-formamide	Investigative	10907740	C23H17F6NO6S	549.4	C1=CC(=CC=C1C(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BF3U8K	(4S,5S)-2-Styryl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394637	C13H13NOS	231.32	C=C[C@H]1[C@@H](N=C(O1)/C=C/C2=CC=CC=C2)S	Ki = 92000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF3U8K	(4S,5S)-2-Styryl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394637	C13H13NOS	231.32	C=C[C@H]1[C@@H](N=C(O1)/C=C/C2=CC=CC=C2)S	Ki = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BF6JZ9	CID 66559934	Investigative	66559934	C27H29F3N8O2S3	650.8	C=CCCNC1=NC(=NC(=N1)N2CCC[C@@H]2CNS(=O)(=O)C3=CC=C(C=C3)C(F)(F)F)NCC4=CSC(=N4)C5=CC=CS5	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BF6SU7	5-{(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide	Investigative	9924640	C17H28N4O4	352.4	CN(C)C(=O)C1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BF6WH4	N-Hydroxy-N-{1-(2-hydroxy-ethoxymethyl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	10116618	C19H20F3NO8S	479.4	C1=CC(=CC=C1OC2=CC=C(C=C2)S(=O)(=O)CC(COCCO)N(C=O)O)OC(F)(F)F	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF6ZI1	N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide	Investigative	44479458	C20H17NO6S2	431.5	CS(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BF6ZI1	N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide	Investigative	44479458	C20H17NO6S2	431.5	CS(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 16	BF6ZI1	N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide	Investigative	44479458	C20H17NO6S2	431.5	CS(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BF6ZI1	N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide	Investigative	44479458	C20H17NO6S2	431.5	CS(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BF78EK	N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonamido)-acetamide	Investigative	44219903	C17H20N2O6S	380.4	CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 59000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF8B7I	((4S,5S)-2-Phenylethynyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol	Investigative	44394682	C14H13NO2	227.26	C=C[C@H]1[C@@H](N=C(O1)C#CC2=CC=CC=C2)CO	Ki = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BF9I5J	(4S,5S)-2-(4-Bromo-phenyl)-4-phenylsulfanyl-5-vinyl-4,5-dihydro-oxazole	Investigative	44394671	C17H14BrNOS	360.3	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)Br)SC3=CC=CC=C3	Ki = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BFB0L4	5-Pyridin-3-yl-1H-indole-2-carboxylic acid ethyl ester	Investigative	56850271	C16H14N2O2	266.29	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C3=CN=CC=C3	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BFBK27	Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445230	C16H11NO3	265.26	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=O)N3	IC50 = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BFBK27	Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445230	C16H11NO3	265.26	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=O)N3	IC50 = 97000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BFBK27	Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445230	C16H11NO3	265.26	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=O)N3	IC50 = 103000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BFBK27	Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445230	C16H11NO3	265.26	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=O)N3	IC50 = 125000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BFJ52V	(S)-2-{4'-[(5-Chloro-4-isopropoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid	Investigative	11330861	C30H31ClN2O7S	599.1	CC1=C(OC2=C1C(=C(C=C2)Cl)OC(C)C)C(=O)NC3=CC=C(C=C3)C4=CC=C(C=C4)S(=O)(=O)N[C@@H](C(C)C)C(=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BFK93U	4-(5-(Biphenyl-4-yl)-4-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485508	C22H16BrN5	430.3	C1=CC=C(C=C1)C2=CC=C(C=C2)C3=C(C=C(N3)C4=NC=CC5=C4N=C(N5)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BFQS36	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-chlorophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036768	C17H10ClN3OS2	371.9	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC=C(C=C4)Cl)/S3	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BFZ48U	3-Hydroxy-4H-pyran-4-thione	Investigative	11355488	C5H4O2S	128.15	C1=COC=C(C1=S)O	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BG02JR	4-(3,4-Dibromo-5-methyl-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485486	C11H9Br2N5	371.03	CC1=C(C(=C(N1)C2=NC=CC3=C2N=C(N3)N)Br)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG18OL	Acetic acid 3-acetoxy-5-methoxy-2-methyl-6-(3,10,12-trihydroxy-2-methoxy-3-methyl-4,6,11-trioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-tetrahydro-pyran-4-yl ester	Investigative	44326187	C31H32O14	628.6	CC1C(C(C(C(O1)O[C@H]2[C@@H]([C@](C(=O)C3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5O)(C)O)OC)OC)OC(=O)C)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG47FV	(4R)-5-Oxo-5-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]-4-[(3,4,5-trimethoxybenzoyl)amino]pentanoic acid	Investigative	44582868	C24H26N4O9S2	578.6	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CS3	IC50 = 55300 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG47RP	(S,E)-5-(4-Bromophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582588	C22H23BrN2O6	491.3	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Br)OC	IC50 = 71200 nM	Poor binder
T80942	Matrix metalloproteinase 9	BG4QJ1	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-2-amino-4-fluoropent-4-enoic acid	Investigative	71465466	C18H19FN2O5S	394.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CC(=C)F)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG4QJ1	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-2-amino-4-fluoropent-4-enoic acid	Investigative	71465466	C18H19FN2O5S	394.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CC(=C)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BG7P3F	Cyclohexanamine;2-methylpropylcarbamoylphosphonic acid	Investigative	9882151	C11H25N2O4P	280.3	CC(C)CNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BG7P3F	Cyclohexanamine;2-methylpropylcarbamoylphosphonic acid	Investigative	9882151	C11H25N2O4P	280.3	CC(C)CNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG7P3F	Cyclohexanamine;2-methylpropylcarbamoylphosphonic acid	Investigative	9882151	C11H25N2O4P	280.3	CC(C)CNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG7SM6	(2R)-2-Amino-N-[(2S)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-3-hydroxy-1-oxopropan-2-yl]-3-phenylpropanamide	Investigative	56658263	C21H27N5O6	445.5	C1=CC=C(C=C1)C[C@H](C(=O)N[C@@H](CO)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N	IC50 = 110100 nM	Poor binder
T80942	Matrix metalloproteinase 3	BG91IE	5-Dodecylamino-3H-[1,3,4]thiadiazole-2-thione	Investigative	44285686	C14H27N3S2	301.5	CCCCCCCCCCCCNC1=NNC(=S)S1	IC50 = 97000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BG9U0C	Cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445203	C12H15NO3	221.25	C1CCC(CC1)OC(=O)C2=CC=CC(=O)N2	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BG9U0C	Cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445203	C12H15NO3	221.25	C1CCC(CC1)OC(=O)C2=CC=CC(=O)N2	IC50 = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BG9U0C	Cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445203	C12H15NO3	221.25	C1CCC(CC1)OC(=O)C2=CC=CC(=O)N2	IC50 = 101000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGA1L5	N-[2-[4-[4-(Trifluoromethoxy)phenoxy]phenylsulfonyl]-1-[(R)-tetrahydrofuran-2-yl]ethyl]-N-hydroxyformamide	Investigative	90667652	C20H20F3NO7S	475.4	C1C[C@@H](OC1)C(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BGC4A9	(2S)-2-(Dibenzothiophen-2-ylsulfonylamino)-3-methylbutanoic acid	Investigative	45269911	C17H17NO4S2	363.5	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)SC3=CC=CC=C32	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGH43F	3-[2-Cyclohexyl-1-(2-methoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-6-phenyl-hexanoic acid	Investigative	44315167	C26H38N2O6	474.6	COC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCC2=CC=CC=C2)CC(=O)O	Ki = 57543.99 nM	Poor binder
T80942	Matrix metalloproteinase 14	BGM15D	(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4-dihydroxy-5-methoxybenzoate	Investigative	42623564	C23H20O10	456.4	COC1=CC(=CC(=C1O)O)C(=O)O[C@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BGM15D	(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4-dihydroxy-5-methoxybenzoate	Investigative	42623564	C23H20O10	456.4	COC1=CC(=CC(=C1O)O)C(=O)O[C@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BGN20Z	(S)-3-Methyl-2-(8-(thiazol-2-yl)dibenzo[b,d]furan-3-sulfonamido)butanoic acid	Investigative	56835063	C20H18N2O5S2	430.5	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C3=C(O2)C=CC(=C3)C4=NC=CS4	IC50 = 57700 nM	Poor binder
T80942	Matrix metalloproteinase 13	BGN26Y	5-(4-(Benzofuran-2-yl)phenyl)-3-hydroxypentanoic acid	Investigative	45482997	C19H18O4	310.3	C1=CC=C2C(=C1)C=C(O2)C3=CC=C(C=C3)CCC(CC(=O)O)O	IC50 = 50200 nM	Poor binder
T80942	Matrix metalloproteinase 13	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 58000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 77000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 89000 nM	Poor binder
T80942	Matrix metalloproteinase 16	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 93000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BGPR53	N-Hydroxy-4-methylbenzenesulfonamide	Investigative	10081163	C7H9NO3S	187.22	CC1=CC=C(C=C1)S(=O)(=O)NO	Ki = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BGPR53	N-Hydroxy-4-methylbenzenesulfonamide	Investigative	10081163	C7H9NO3S	187.22	CC1=CC=C(C=C1)S(=O)(=O)NO	Ki = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGPR53	N-Hydroxy-4-methylbenzenesulfonamide	Investigative	10081163	C7H9NO3S	187.22	CC1=CC=C(C=C1)S(=O)(=O)NO	Ki = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGPR53	N-Hydroxy-4-methylbenzenesulfonamide	Investigative	10081163	C7H9NO3S	187.22	CC1=CC=C(C=C1)S(=O)(=O)NO	Ki = 77000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGTX61	(R)-5-(2-Nicotinoylhydrazinyl)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582875	C21H24N4O8	460.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NNC(=O)C2=CN=CC=C2	IC50 = 114900 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGU8W6	N-Hydroxy-N-{4-morpholin-4-yl-4-oxo-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-butyl}-formamide	Investigative	10209301	C23H25F3N2O8S	546.5	C1COCCN1C(=O)CCC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGV36J	(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394703	C12H13NOS	219.3	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)S	Ki = 88000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BGV36J	(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394703	C12H13NOS	219.3	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)S	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGV36J	(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394703	C12H13NOS	219.3	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)S	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGXT10	2-Bromobenzyl 6-mercaptopicolinate	Investigative	44445262	C13H10BrNO2S	324.19	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=S)N2)Br	IC50 = 108000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BGXT10	2-Bromobenzyl 6-mercaptopicolinate	Investigative	44445262	C13H10BrNO2S	324.19	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=S)N2)Br	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BGXT10	2-Bromobenzyl 6-mercaptopicolinate	Investigative	44445262	C13H10BrNO2S	324.19	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=S)N2)Br	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGXT10	2-Bromobenzyl 6-mercaptopicolinate	Investigative	44445262	C13H10BrNO2S	324.19	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=S)N2)Br	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 ~ 120000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BH0Q9X	N-Hydroxy-2-[4-[3-bromo-5-(p-anisyl)benzyloxy]phenylsulfonylamino]acetamide	Investigative	72714085	C22H21BrN2O6S	521.4	COC1=CC=C(C=C1)C2=CC(=CC(=C2)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO)Br	IC50 = 170000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BH30VB	Chembl4278980	Investigative	145980521	C23H29NO9S	495.5	CC(C)[C@H](C(=O)O)N([C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)S(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BH46IF	(2S)-2-[[4-(3-Fluorophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid	Investigative	10831752	C17H18FNO4S	351.4	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC(=CC=C2)F	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BH5V7X	[(4-Hydroxyanilino)-phosphonomethyl]phosphonic acid	Investigative	72204933	C7H11NO7P2	283.11	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BH5V7X	[(4-Hydroxyanilino)-phosphonomethyl]phosphonic acid	Investigative	72204933	C7H11NO7P2	283.11	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BH5V7X	[(4-Hydroxyanilino)-phosphonomethyl]phosphonic acid	Investigative	72204933	C7H11NO7P2	283.11	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BH5Z8V	(S)-2-{4'-[(5-Iodo-4-methoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid	Investigative	11456566	C28H27IN2O7S	662.5	CC1=C(OC2=C1C(=C(C=C2)I)OC)C(=O)NC3=CC=C(C=C3)C4=CC=C(C=C4)S(=O)(=O)N[C@@H](C(C)C)C(=O)O	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BH60GQ	(R)-5-Oxo-5-(2-(thiazole-2-carbonyl)hydrazinyl)-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582874	C19H22N4O8S	466.5	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NNC(=O)C2=NC=CS2	IC50 = 169400 nM	Poor binder
T80942	Matrix metalloproteinase 9	BH6VR3	(4R)-N-Hydroxy-3-naphthalen-2-ylsulfonyl-1,3-thiazolidine-4-carboxamide	Investigative	57393181	C14H14N2O4S2	338.4	C1[C@H](N(CS1)S(=O)(=O)C2=CC3=CC=CC=C3C=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BH7FI5	Naphthalen-2-yl 6-mercaptopicolinate	Investigative	44445264	C16H11NO2S	281.3	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=S)N3	IC50 = 99000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BH7FI5	Naphthalen-2-yl 6-mercaptopicolinate	Investigative	44445264	C16H11NO2S	281.3	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=S)N3	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BH7FI5	Naphthalen-2-yl 6-mercaptopicolinate	Investigative	44445264	C16H11NO2S	281.3	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=S)N3	IC50 = 101000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BH7FI5	Naphthalen-2-yl 6-mercaptopicolinate	Investigative	44445264	C16H11NO2S	281.3	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=S)N3	IC50 = 119000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BH7L0B	4-(3,5-Dibromo-4-(4-(trifluoromethyl)phenethyl)-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485461	C19H14Br2F3N5	529.2	C1=CC(=CC=C1CCC2=C(NC(=C2Br)C3=NC=CC4=C3N=C(N4)N)Br)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BHJA06	(2S)-2-Amino-4-methylthio-N-[(2R)-2-amino-3-phenylpropyl]butyramide	Investigative	42645511	C14H23N3OS	281.42	CSCC[C@@H](C(=O)NC[C@@H](CC1=CC=CC=C1)N)N	IC50 = 112100 nM	Poor binder
T80942	Matrix metalloproteinase 12	BHK5T0	Thiophen-3-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445237	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 62000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BHK5T0	Thiophen-3-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445237	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BHK5T0	Thiophen-3-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445237	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BHK6A7	(2R)-2-Amino-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	44356667	C21H34N4O3	390.5	CC(C)C[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BHK6A7	(2R)-2-Amino-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	44356667	C21H34N4O3	390.5	CC(C)C[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BHKF38	Epicatechin 3-O-(3-O-methylgallate)	Investigative	467296	C23H20O10	456.4	COC1=CC(=CC(=C1O)O)C(=O)O[C@@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O	IC50 = 88000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BHKF38	Epicatechin 3-O-(3-O-methylgallate)	Investigative	467296	C23H20O10	456.4	COC1=CC(=CC(=C1O)O)C(=O)O[C@@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BHL76P	(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,5-dihydroxy-4-methoxybenzoate	Investigative	42623563	C23H20O10	456.4	COC1=C(C=C(C=C1O)C(=O)O[C@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BHL76P	(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,5-dihydroxy-4-methoxybenzoate	Investigative	42623563	C23H20O10	456.4	COC1=C(C=C(C=C1O)C(=O)O[C@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BHOA54	(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(1-methoxy-3-methyl-1-oxobutan-2-ylamino)-5-oxopentanoic acid	Investigative	44582719	C22H30N2O8	450.5	CC(C)C(C(=O)OC)NC(=O)[C@H](CCC(=O)O)NC(=O)/C=C/C1=CC(=C(C=C1)OC)OC	IC50 = 76800 nM	Poor binder
T80942	Matrix metalloproteinase 9	BHR8Z5	Chembl4211189	Investigative	145964116	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)O	IC50 = 72600 nM	Poor binder
T80942	Matrix metalloproteinase 8	BHR8Z5	Chembl4211189	Investigative	145964116	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)O	IC50 = 77400 nM	Poor binder
T80942	Matrix metalloproteinase 1	BHX3A1	N-({4'-[(4-Isobutyrylphenoxy)methyl]biphenyl-4-Yl}sulfonyl)-D-Valine	Investigative	11691964	C28H31NO6S	509.6	CC(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)COC3=CC=C(C=C3)C(=O)C(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BI2GT9	2-Benzyl-N-hydroxy-3-morpholino-3-oxopropanamide	Investigative	10540548	C14H18N2O4	278.3	C1COCCN1C(=O)C(CC2=CC=CC=C2)C(=O)NO	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BI3S2D	2-(3''-Bromo-biphenyl-4-sulfonylamino)-3-methyl-butyric acid	Investigative	10692994	C17H18BrNO4S	412.3	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC(=CC=C2)Br	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BI3S2D	2-(3''-Bromo-biphenyl-4-sulfonylamino)-3-methyl-butyric acid	Investigative	10692994	C17H18BrNO4S	412.3	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC(=CC=C2)Br	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BI3S2D	2-(3''-Bromo-biphenyl-4-sulfonylamino)-3-methyl-butyric acid	Investigative	10692994	C17H18BrNO4S	412.3	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC(=CC=C2)Br	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BI3VS2	(S)-Benzyl-2-(2-(3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoate	Investigative	49863560	C26H30N4O6	494.5	C[C@@H](C(=O)OCC1=CC=CC=C1)NC(=O)CN2C(=O)CC[C@@H](C2=O)NC(=O)[C@H](CC3=CC=CC=C3)N	IC50 = 129000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BI4C0G	Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71449332	C26H27NO4	417.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCCC3=CC=CC=C3)C(=O)OC	IC50 = 85500 nM	Poor binder
T80942	Matrix metalloproteinase 2	BI73TH	4-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445255	C13H10FNO2S	263.29	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 108000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BI73TH	4-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445255	C13H10FNO2S	263.29	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 112000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BI73TH	4-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445255	C13H10FNO2S	263.29	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BI73TH	4-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445255	C13H10FNO2S	263.29	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BI74SE	(2R)-N-[(2S)-3,3-Dimethyl-1-oxo-1-[[(1R)-1-phenylethyl]amino]butan-2-yl]-N'-hydroxy-2-[3-[4-phenyl-3-(trifluoromethyl)phenyl]propyl]butanediamide	Investigative	44369163	C34H40F3N3O4	611.7	C[C@H](C1=CC=CC=C1)NC(=O)[C@H](C(C)(C)C)NC(=O)[C@H](CCCC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CC(=O)NO	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BI7Y5L	1,1,1-Trifluoro-N-hydroxymethanesulfonamide	Investigative	23644662	CH2F3NO3S	165.09	C(F)(F)(F)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BI7Y5L	1,1,1-Trifluoro-N-hydroxymethanesulfonamide	Investigative	23644662	CH2F3NO3S	165.09	C(F)(F)(F)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BI7Y5L	1,1,1-Trifluoro-N-hydroxymethanesulfonamide	Investigative	23644662	CH2F3NO3S	165.09	C(F)(F)(F)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BI7Y5L	1,1,1-Trifluoro-N-hydroxymethanesulfonamide	Investigative	23644662	CH2F3NO3S	165.09	C(F)(F)(F)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BI8BQ6	Cyclohexylcarbamoylphosphonic Acid	Investigative	9837496	C7H14NO4P	207.16	C1CCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BI8BQ6	Cyclohexylcarbamoylphosphonic Acid	Investigative	9837496	C7H14NO4P	207.16	C1CCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BIC4X9	6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid biphenyl-3-ylmethyl ester	Investigative	44445233	C19H15NO3	305.3	C1=CC=C(C=C1)C2=CC=CC(=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 99000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BID20Z	Benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445204	C13H11NO3	229.23	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BID20Z	Benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445204	C13H11NO3	229.23	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BID20Z	Benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445204	C13H11NO3	229.23	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BIDO53	Thiophen-3-yl 6-mercaptopicolinate	Investigative	44445269	C10H7NO2S2	237.3	C1=CC(=S)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 77000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BIDO53	Thiophen-3-yl 6-mercaptopicolinate	Investigative	44445269	C10H7NO2S2	237.3	C1=CC(=S)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BIDO53	Thiophen-3-yl 6-mercaptopicolinate	Investigative	44445269	C10H7NO2S2	237.3	C1=CC(=S)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 93000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BIDO53	Thiophen-3-yl 6-mercaptopicolinate	Investigative	44445269	C10H7NO2S2	237.3	C1=CC(=S)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 108000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BIFP05	2-Amino-5-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenol	Investigative	54757202	C15H15NO4S2	337.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC(=C(C=C3)N)O	Ki = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BIFP05	2-Amino-5-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenol	Investigative	54757202	C15H15NO4S2	337.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC(=C(C=C3)N)O	Ki = 116000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BIK0A1	Chembl4211480	Investigative	145965508	C21H14O5	346.3	C1C2=C(C(=C(C=C2)C3=CC=C(C=C3)O)C(=O)C4=CC=C(C=C4)O)C(=O)O1	IC50 = 81210 nM	Poor binder
T80942	Matrix metalloproteinase 14	BIPC43	(2E)-3-(N-Hydroxycarbamoyl)-2-(3-phenylpropylidene)propionyl-L-tryptophan-N-methylamide	Investigative	44434566	C25H28N4O4	448.5	CNC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)/C(=C/CCC3=CC=CC=C3)/CC(=O)NO	IC50 = 53100 nM	Poor binder
T80942	Matrix metalloproteinase 2	BISO86	(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(1-methoxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44582718	C20H26N2O8	422.4	CC(C(=O)OC)NC(=O)[C@H](CCC(=O)O)NC(=O)/C=C/C1=CC(=C(C=C1)OC)OC	IC50 = 83200 nM	Poor binder
T80942	Matrix metalloproteinase 3	BIT3C5	(4S)-5-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]amino]-5-oxo-4-[3-(4-phenylphenyl)propanoylamino]pentanoic acid	Investigative	50992325	C26H33N3O5	467.6	CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CCC1=CC=C(C=C1)C2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BIV63S	5-(4''-(Benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	45483036	C24H24O4	376.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=CC=C(C=C3)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BIV63S	5-(4''-(Benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	45483036	C24H24O4	376.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=CC=C(C=C3)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BIV97T	(2S)-2-Amino-N-[(3S)-1-[2-(2-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863934	C22H23FN4O4	426.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC=CC=C3F	IC50 = 62700 nM	Poor binder
T80942	Matrix metalloproteinase 9	BIZ03M	2,3-Bis(1-(dimethylamino)naphthalene-5-sulfonamido)-N-hydroxypropanamide	Investigative	44576808	C27H31N5O6S2	585.7	CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NCC(C(=O)NO)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C	Ki = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BIZX05	N-[(E)-1-(2-Chlorophenyl)ethylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide	Investigative	127030239	C19H17ClN4O2	368.8	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C(\\C)/C3=CC=CC=C3Cl	IC50 = 112260 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJ06HE	(2R)-3-Methyl-2-[[4-[4-[(5-oxo-7,8-dihydro-6H-naphthalen-2-yl)oxymethyl]phenyl]phenyl]sulfonylamino]butanoic acid	Investigative	11569716	C28H29NO6S	507.6	CC(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)COC3=CC4=C(C=C3)C(=O)CCC4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJ0K8P	(2S)-2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]-3-phenylpropanoic acid	Investigative	10551910	C21H18BrNO4S	460.3	C1=CC=C(C=C1)C[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Br	IC50 = 56000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BJ0K8P	(2S)-2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]-3-phenylpropanoic acid	Investigative	10551910	C21H18BrNO4S	460.3	C1=CC=C(C=C1)C[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Br	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJ0LR6	Thioacetic acid S-[(4S,5S)-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester	Investigative	44394645	C15H15NO2S	273.4	CC(=O)S[C@H]1[C@@H](OC(=N1)/C=C/C2=CC=CC=C2)C=C	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BJ0LR6	Thioacetic acid S-[(4S,5S)-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester	Investigative	44394645	C15H15NO2S	273.4	CC(=O)S[C@H]1[C@@H](OC(=N1)/C=C/C2=CC=CC=C2)C=C	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BJ27VX	Isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445199	C9H11NO3	181.19	CC(C)OC(=O)C1=CC=CC(=O)N1	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJ27VX	Isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445199	C9H11NO3	181.19	CC(C)OC(=O)C1=CC=CC(=O)N1	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BJ27VX	Isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445199	C9H11NO3	181.19	CC(C)OC(=O)C1=CC=CC(=O)N1	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BJ2YI8	Cruzain-IN-1	Investigative	44143088	C14H10F2N6	300.27	CCN1C=NC2=C(N=C(N=C21)C#N)NC3=CC(=CC(=C3)F)F	IC50 = 72443.6 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJ3L1G	N-(4-Amino-2-methylquinolin-6-yl)-4-quinolin-3-ylbenzamide	Investigative	73055902	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)C4=CC5=CC=CC=C5N=C4)N	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJ5Y9M	Ethyl 3-(hydroxyamino)-3-oxo-2-phenylpropanoate	Investigative	10775444	C11H13NO4	223.22	CCOC(=O)C(C1=CC=CC=C1)C(=O)NO	Ki = 97723.72 nM	Poor binder
T80942	Matrix metalloproteinase 3	BJ6W4D	4-(4-Methoxyphenyl)-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide	Investigative	3649035	C18H22N2O3S	346.4	COC1=CC=C(C=C1)C2=CSC(=C2)C(=O)NCCN3CCOCC3	IC50 ~ 101000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJ6W4D	4-(4-Methoxyphenyl)-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide	Investigative	3649035	C18H22N2O3S	346.4	COC1=CC=C(C=C1)C2=CSC(=C2)C(=O)NCCN3CCOCC3	IC50 ~ 101000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJ6W4D	4-(4-Methoxyphenyl)-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide	Investigative	3649035	C18H22N2O3S	346.4	COC1=CC=C(C=C1)C2=CSC(=C2)C(=O)NCCN3CCOCC3	IC50 ~ 101000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJ76ZM	Chembl4206886	Investigative	145976412	C50H56N4O5S	825.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7	IC50 = 52500 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJ76ZM	Chembl4206886	Investigative	145976412	C50H56N4O5S	825.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7	IC50 = 53600 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJ8Y6K	[1-[[4-(6-Fluoropyridin-3-yl)phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029507	C15H18FN2O5PS	388.4	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C=C2)F)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJF61I	N-(2-Methyl-4-amino-6-quinolyl)-3-(2-methoxyphenyl)propionamide	Investigative	73055018	C20H21N3O2	335.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJF61I	N-(2-Methyl-4-amino-6-quinolyl)-3-(2-methoxyphenyl)propionamide	Investigative	73055018	C20H21N3O2	335.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJHU70	(1R,2R,5S)-2-[(2,4-Dioxopyrido[1,2-a][1,3,5]triazin-3-yl)methyl]-5-[4-(4-methylsulfanylphenyl)phenyl]sulfanylcyclopentane-1-carboxylic acid	Investigative	11092551	C27H25N3O4S2	519.6	CSC1=CC=C(C=C1)C2=CC=C(C=C2)S[C@H]3CC[C@H]([C@@H]3C(=O)O)CN4C(=O)N=C5C=CC=CN5C4=O	IC50 = 63000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BJI49R	Chembl4202455	Investigative	145977231	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJI49R	Chembl4202455	Investigative	145977231	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJI49R	Chembl4202455	Investigative	145977231	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BJK4U1	Chembl4202528	Investigative	145976230	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJK4U1	Chembl4202528	Investigative	145976230	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJK4U1	Chembl4202528	Investigative	145976230	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJM5H0	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile	Investigative	5941957	C17H12IN3O	401.2	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)I	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJM5H0	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile	Investigative	5941957	C17H12IN3O	401.2	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)I	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BJM5H0	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile	Investigative	5941957	C17H12IN3O	401.2	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)I	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJR8V5	N-(4-Amino-2-methylquinolin-6-yl)-3-[2-(trifluoromethyl)phenyl]propanamide	Investigative	73056183	C20H18F3N3O	373.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJR8V5	N-(4-Amino-2-methylquinolin-6-yl)-3-[2-(trifluoromethyl)phenyl]propanamide	Investigative	73056183	C20H18F3N3O	373.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3C(F)(F)F)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BJV8M0	((R)-1-{4-[2-(4-Methoxy-phenyl)-ethyl]-benzenesulfonylamino}-2-methyl-propyl)-phosphonic acid	Investigative	44422749	C19H26NO6PS	427.5	CC(C)[C@H](NS(=O)(=O)C1=CC=C(C=C1)CCC2=CC=C(C=C2)OC)P(=O)(O)O	IC50 = 130000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BJW19F	3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445278	C14H13N5	251.29	C1=CC=C(C=C1)CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJW19F	3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445278	C14H13N5	251.29	C1=CC=C(C=C1)CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BJW19F	3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445278	C14H13N5	251.29	C1=CC=C(C=C1)CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BJW19F	3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445278	C14H13N5	251.29	C1=CC=C(C=C1)CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJW37Y	N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]acetamide	Investigative	72714082	C15H14Br2N2O5S	494.2	C1=CC(=CC=C1OCC2=CC(=CC(=C2)Br)Br)S(=O)(=O)NCC(=O)NO	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BJW37Y	N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]acetamide	Investigative	72714082	C15H14Br2N2O5S	494.2	C1=CC(=CC=C1OCC2=CC(=CC(=C2)Br)Br)S(=O)(=O)NCC(=O)NO	IC50 = 113000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BJWP32	1-Phenyl-3-(5-sulfanyl-1,3,4-thiadiazol-2-yl)urea	Investigative	10658473	C9H8N4OS2	252.3	C1=CC=C(C=C1)NC(=O)NC2=NNC(=S)S2	IC50 = 99000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BK12BZ	(5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136814721	C17H11N3O2S2	353.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C\\C4=CC(=CC=C4)O)/S3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BK16HW	(Sec-butylamino)carbonylphosphonic acid	Investigative	11286824	C5H12NO4P	181.13	CCC(C)NC(=O)P(=O)(O)O	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BK16HW	(Sec-butylamino)carbonylphosphonic acid	Investigative	11286824	C5H12NO4P	181.13	CCC(C)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BK16HW	(Sec-butylamino)carbonylphosphonic acid	Investigative	11286824	C5H12NO4P	181.13	CCC(C)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BK1GF6	(S,E)-5-(4-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582568	C22H23ClN2O6	446.9	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Cl)OC	IC50 = 59900 nM	Poor binder
T80942	Matrix metalloproteinase 1	BK2NS9	Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445240	C11H15NO3	209.24	CCCCCOC(=O)C1=CC=CC(=O)N1	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BK2NS9	Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445240	C11H15NO3	209.24	CCCCCOC(=O)C1=CC=CC(=O)N1	IC50 = 66000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BK2NS9	Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445240	C11H15NO3	209.24	CCCCCOC(=O)C1=CC=CC(=O)N1	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BK2NS9	Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445240	C11H15NO3	209.24	CCCCCOC(=O)C1=CC=CC(=O)N1	IC50 = 103000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BK2OM0	(R)-2-Dodecyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)succinamide	Investigative	44302359	C26H43N3O4	461.6	CCCCCCCCCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BK2Y7S	(1R,2S,5R)-2-[2-[4-(4-Chlorophenyl)phenyl]ethylsulfanyl]-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	10929404	C28H26ClN3O3S	520	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)SCCC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 ~ 70000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BK3AN4	N-Benzyl-3-(2-hydroxycarbamoyl-4-methyl-pentanoylamino)-succinamic acid	Investigative	44343404	C18H25N3O6	379.4	CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NCC1=CC=CC=C1)C(=O)NO	Ki = 88000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BK3M2U	Chembl4211771	Investigative	145967177	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 = 87500 nM	Poor binder
T80942	Matrix metalloproteinase 9	BK3M2U	Chembl4211771	Investigative	145967177	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 = 93100 nM	Poor binder
T80942	Matrix metalloproteinase 9	BK3V9T	N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methoxypyridin-3-yl)propanamide	Investigative	73056773	C19H20N4O2	336.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(N=CC=C3)OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BK3V9T	N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methoxypyridin-3-yl)propanamide	Investigative	73056773	C19H20N4O2	336.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(N=CC=C3)OC)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BK4UV8	N-Benzhydryl-2-[1-benzhydryl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328316	C43H38N4O5	690.8	C1=CC=C(C=C1)C(C2=CC=CC=C2)N(CC(=O)NO)C(=O)CN(C(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BK5G4F	(5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136814723	C17H11N3O2S2	353.4	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	IC50 = 97350 nM	Poor binder
T80942	Matrix metalloproteinase 13	BK5G4F	(5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136814723	C17H11N3O2S2	353.4	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BK5X2A	[(4-Fluoro-3-nitroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205112	C7H9FN2O8P2	330.1	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)[N+](=O)[O-])F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BK5X2A	[(4-Fluoro-3-nitroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205112	C7H9FN2O8P2	330.1	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)[N+](=O)[O-])F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BK5X2A	[(4-Fluoro-3-nitroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205112	C7H9FN2O8P2	330.1	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)[N+](=O)[O-])F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BK95NA	3,4-Dichloroanilinomethylenebisphosphonic acid	Investigative	24866945	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BK95NA	3,4-Dichloroanilinomethylenebisphosphonic acid	Investigative	24866945	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKB5V1	1-(4-Amino-2-methylquinolin-6-yl)-3-(4-benzoylphenyl)urea	Investigative	73055605	C24H20N4O2	396.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC=C(C=C3)C(=O)C4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BKB5V1	1-(4-Amino-2-methylquinolin-6-yl)-3-(4-benzoylphenyl)urea	Investigative	73055605	C24H20N4O2	396.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC=C(C=C3)C(=O)C4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BKDS50	2-[(4-But-2-ynoxyphenyl)sulfonylamino]-3-(5-phenylmethoxy-1H-indol-3-yl)propanoic Acid	Investigative	11533683	C28H26N2O6S	518.6	CC#CCOC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CNC3=C2C=C(C=C3)OCC4=CC=CC=C4)C(=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKFL26	3-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445225	C13H10BrNO3	308.13	C1=CC(=CC(=C1)Br)COC(=O)C2=CC=CC(=O)N2	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BKFL26	3-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445225	C13H10BrNO3	308.13	C1=CC(=CC(=C1)Br)COC(=O)C2=CC=CC(=O)N2	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BKG9M5	4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole	Investigative	44445272	C11H18N4O	222.29	CCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKG9M5	4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole	Investigative	44445272	C11H18N4O	222.29	CCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BKG9M5	4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole	Investigative	44445272	C11H18N4O	222.29	CCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BKG9M5	4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole	Investigative	44445272	C11H18N4O	222.29	CCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BKI10F	2-[(4-Chlorophenyl)methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one	Investigative	135412054	C14H13ClN2OS	292.8	C1CC2=C(C1)N=C(NC2=O)SCC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKI10F	2-[(4-Chlorophenyl)methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one	Investigative	135412054	C14H13ClN2OS	292.8	C1CC2=C(C1)N=C(NC2=O)SCC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKJS91	(4S,5S)-2-(4-Bromo-phenyl)-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394595	C11H10BrNOS	284.17	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)Br)S	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BKM83T	4-Chlorobenzyl 6-mercaptopicolinate	Investigative	44445261	C13H10ClNO2S	279.74	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 96000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKM83T	4-Chlorobenzyl 6-mercaptopicolinate	Investigative	44445261	C13H10ClNO2S	279.74	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 112000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BKM83T	4-Chlorobenzyl 6-mercaptopicolinate	Investigative	44445261	C13H10ClNO2S	279.74	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 115000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BKM83T	4-Chlorobenzyl 6-mercaptopicolinate	Investigative	44445261	C13H10ClNO2S	279.74	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 126000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BKM8G4	2-[(4'-Fluorobiphenyl-4-yl)sulfonyl]benzeneacetic acid	Investigative	71602248	C20H15FO4S	370.4	C1=CC=C(C(=C1)CC(=O)O)S(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)F	IC50 = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BKP74E	2-Hydroxycarbamoyl-4-methyl-pentanoic acid ethyl ester	Investigative	10584303	C9H17NO4	203.24	CCOC(=O)C(CC(C)C)C(=O)NO	Ki = 190000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BKQZ26	2-(2-(3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)acetic acid	Investigative	49863590	C18H22N4O6	390.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NCC(=O)O	IC50 = 107000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BKS4B1	(E)-5-(4-Hydroxy-3-methoxyphenyl)-2-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide	Investigative	49806130	C28H25NO7	487.5	COC1=C(C=CC(=C1)/C=C/C(=O)C(C(=O)NC2=CC=CC=C2)C(=O)/C=C/C3=CC(=C(C=C3)O)OC)O	IC50 = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BKZ4T1	N-Hydroxy-2-[4-[4-(trifluoromethoxy)benzyloxy]phenylsulfonylamino]acetamide	Investigative	72713862	C16H15F3N2O6S	420.4	C1=CC(=CC=C1COC2=CC=C(C=C2)S(=O)(=O)NCC(=O)NO)OC(F)(F)F	IC50 = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BL1Z7E	N-Hydroxy-N''-[(S)-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-oxalamide	Investigative	44384090	C13H17N3O4	279.29	C[C@@H](C1=CC=CC=C1)NC(=O)[C@H](C)NC(=O)C(=O)NO	Ki = 180000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BL2F0S	6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445206	C14H13NO3	243.26	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BL2F0S	6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445206	C14H13NO3	243.26	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BL2F0S	6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445206	C14H13NO3	243.26	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BL2F0S	6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445206	C14H13NO3	243.26	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BL58TM	Chembl4162521	Investigative	145957734	C15H21N3O7S	387.4	CCCCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 111350 nM	Poor binder
T80942	Matrix metalloproteinase 12	BL58TM	Chembl4162521	Investigative	145957734	C15H21N3O7S	387.4	CCCCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 198300 nM	Poor binder
T80942	Matrix metalloproteinase 1	BL9W0M	N-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-N-hydroxyformamide	Investigative	21699977	C16H14N2O3	282.29	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCN(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BLF02U	4-{3-(Formyl-hydroxy-amino)-4-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-butyl}-benzoic acid	Investigative	10166232	C25H22F3NO8S	553.5	C1=CC(=CC=C1CCC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BLF1I4	Chembl4207344	Investigative	145975699	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BLF1I4	Chembl4207344	Investigative	145975699	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BLF1I4	Chembl4207344	Investigative	145975699	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BLHG74	N-Hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(1,2,3,4-tetrahydro-naphthalen-1-yl)-ureido]-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide	Investigative	44328317	C37H38N4O5	618.7	C1CC(C2=CC=CC=C2C1)N(CC(=O)NO)C(=O)CN(C3CCCC4=CC=CC=C34)C(=O)NC5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BLO62C	Prop-2-enyl 3-(3,4-dimethoxyphenyl)-2-[(E)-3-[4-(trifluoromethyl)phenyl]prop-2-enoyl]oxypropanoate	Investigative	71654192	C24H23F3O6	464.4	COC1=C(C=C(C=C1)CC(C(=O)OCC=C)OC(=O)/C=C/C2=CC=C(C=C2)C(F)(F)F)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BLU89J	N-(4'-Fluoro-1,1'-biphenyl-4-ylsulfonyl)valine	Investigative	10665624	C17H18FNO4S	351.4	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)F	IC50 = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BLW39J	N-Hydroxy-2-[4-(3-fluorobenzyloxy)phenylsulfonylamino]acetamide	Investigative	72713865	C15H15FN2O5S	354.4	C1=CC(=CC(=C1)F)COC2=CC=C(C=C2)S(=O)(=O)NCC(=O)NO	IC50 = 61000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BM0P4L	4-(4,5-Dibromo-1H-pyrrol-2-yl)-N,N-dimethyl-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	44426077	C12H11Br2N5	385.06	CN(C)C1=NC2=C(N1)C=CN=C2C3=CC(=C(N3)Br)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BM3O5C	(2R)-2-Amino-N-[(2S)-3-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-2-hydroxy-3-oxopropyl]-3-phenylpropanamide	Investigative	56665196	C21H27N5O6	445.5	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)O)N	IC50 = 108900 nM	Poor binder
T80942	Matrix metalloproteinase 2	BM7PR2	(2S)-N-Butyl-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide	Investigative	46232490	C24H28N4O3	420.5	CCCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN2C3=CC=CC=C3N=C(C2=O)C	IC50 = 106000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BMC90G	N-[(E)-(4-Chlorophenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide	Investigative	14616300	C18H15ClN4O2	354.8	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=CC=C(C=C3)Cl	IC50 = 81010 nM	Poor binder
T80942	Matrix metalloproteinase 1	BMC9X6	4-{(5Z)-2,4-Dioxo-5-[(2E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl}butanoic acid	Investigative	1348435	C16H15NO4S	317.4	C1=CC=C(C=C1)/C=C/C=C\\2/C(=O)N(C(=O)S2)CCCC(=O)O	IC50 = 93000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BMC9X6	4-{(5Z)-2,4-Dioxo-5-[(2E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl}butanoic acid	Investigative	1348435	C16H15NO4S	317.4	C1=CC=C(C=C1)/C=C/C=C\\2/C(=O)N(C(=O)S2)CCCC(=O)O	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BMI8C2	Isopropyl 6-mercaptopicolinate	Investigative	44445241	C9H11NO2S	197.26	CC(C)OC(=O)C1=CC=CC(=S)N1	IC50 = 121000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BMI8C2	Isopropyl 6-mercaptopicolinate	Investigative	44445241	C9H11NO2S	197.26	CC(C)OC(=O)C1=CC=CC(=S)N1	IC50 = 132000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BMI8C2	Isopropyl 6-mercaptopicolinate	Investigative	44445241	C9H11NO2S	197.26	CC(C)OC(=O)C1=CC=CC(=S)N1	IC50 = 146000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BMI8C2	Isopropyl 6-mercaptopicolinate	Investigative	44445241	C9H11NO2S	197.26	CC(C)OC(=O)C1=CC=CC(=S)N1	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BMLF38	N-[(2r)-2-(Hydroxycarbamoyl)-4-Methylpentanoyl]-L-Alanylglycinamide	Investigative	5496618	C12H22N4O5	302.33	C[C@@H](C(=O)NCC(=O)N)NC(=O)[C@H](CC(C)C)C(=O)NO	Ki = 121000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BMUX74	2-(5-{(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazol-3-yl)isonicotinic acid	Investigative	16748789	C20H26N4O5	402.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BN09KR	N-(4-Amino-2-methylquinolin-6-yl)-4-pyridin-3-ylbenzamide	Investigative	73054736	C22H18N4O	354.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)C4=CN=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BN39PI	(2S)-2-Amino-N-[(3S)-1-[2-(3-chloroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863933	C22H23ClN4O4	442.9	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC(=CC=C3)Cl	IC50 = 60400 nM	Poor binder
T80942	Matrix metalloproteinase 1	BN6V9X	N-[1-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide	Investigative	11027718	C22H24F3NO8S	519.5	CC1(OC[C@@H](O1)CC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BN7RG4	1,5-Dimethyl-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione	Investigative	44384994	C18H16N2O4	324.3	CC1(C(=O)NC(=O)N(C1=O)C)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BN7RG4	1,5-Dimethyl-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione	Investigative	44384994	C18H16N2O4	324.3	CC1(C(=O)NC(=O)N(C1=O)C)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BN7RG4	1,5-Dimethyl-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione	Investigative	44384994	C18H16N2O4	324.3	CC1(C(=O)NC(=O)N(C1=O)C)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BN83ED	(5S)-5-[[4-[5-[(4-Fluorophenyl)methoxy]pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-5-methylimidazolidine-2,4-dione	Investigative	73346037	C20H23FN6O5S	478.5	C[C@]1(C(=O)NC(=O)N1)CS(=O)(=O)N2CCN(CC2)C3=NC=C(C=N3)OCC4=CC=C(C=C4)F	IC50 ~ 99999 nM	Poor binder
T80942	Matrix metalloproteinase 9	BN9V7C	(4S,5S)-2-Biphenyl-4-yl-4-phenylsulfanyl-5-vinyl-4,5-dihydro-oxazole	Investigative	44394765	C23H19NOS	357.5	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)C3=CC=CC=C3)SC4=CC=CC=C4	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BN9ZG7	(2S)-3-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-hydroxypropanamide	Investigative	56661758	C12H18N4O5	298.3	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CN)O)N)O)[N+](=O)[O-]	IC50 = 100100 nM	Poor binder
T80942	Matrix metalloproteinase 8	BND24P	Ethyl 2-(hydroxycarbamoyl)-3-methylbutanoate	Investigative	44445914	C8H15NO4	189.21	CCOC(=O)C(C(C)C)C(=O)NO	Ki = 190546.07 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNEM74	2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445217	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNEM74	2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445217	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BNEM74	2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445217	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BNEM74	2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445217	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNF4H3	(2R)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-3-phenylpropanamide	Investigative	56672135	C18H24N4O2	328.4	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)N)O)N)N	IC50 = 149200 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNFP12	(S,E)-5-(3,5-Difluorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582644	C22H22F2N2O6	448.4	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC(=CC(=C2)F)F)OC	IC50 = 116300 nM	Poor binder
T80942	Matrix metalloproteinase 8	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BNJ04P	5-(Phenylamino)-1,3,4-thiadiazole-2(3H)-thione	Investigative	707055	C8H7N3S2	209.3	C1=CC=C(C=C1)NC2=NNC(=S)S2	IC50 = 190000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNOK60	2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445213	C13H10FNO3	247.22	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BNOK60	2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445213	C13H10FNO3	247.22	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNOK60	2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445213	C13H10FNO3	247.22	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BNOK60	2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445213	C13H10FNO3	247.22	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNOR68	N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide	Investigative	127033875	C20H20N4O4	380.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=C(C=C(C=C3)OC)OC	IC50 = 74910 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNP8H6	(2R,3R)-N-(2-(4-Benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide	Investigative	46184724	C27H30N2O4S	478.6	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCCC2=CC(=CS2)CC3=CC=CC=C3)O)O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNP8H6	(2R,3R)-N-(2-(4-Benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide	Investigative	46184724	C27H30N2O4S	478.6	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCCC2=CC(=CS2)CC3=CC=CC=C3)O)O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNQK37	MMP Inhibitor, 3	Investigative	50991679	C29H31N3O7S	565.6	C1=CC=C(C=C1)C2=CSC(=C2)C3=CC=C(C=C3)CCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](CCC(=O)O)C(=O)N	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BNTY08	(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445281	C16H15N5	277.32	C1=CC=C(C=C1)/C=C/CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BNTY08	(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445281	C16H15N5	277.32	C1=CC=C(C=C1)/C=C/CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNTY08	(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445281	C16H15N5	277.32	C1=CC=C(C=C1)/C=C/CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNTY08	(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445281	C16H15N5	277.32	C1=CC=C(C=C1)/C=C/CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNU1Q2	Cyclohexyl 6-mercaptopicolinate	Investigative	44445243	C12H15NO2S	237.32	C1CCC(CC1)OC(=O)C2=CC=CC(=S)N2	IC50 = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BNU1Q2	Cyclohexyl 6-mercaptopicolinate	Investigative	44445243	C12H15NO2S	237.32	C1CCC(CC1)OC(=O)C2=CC=CC(=S)N2	IC50 = 87000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BNU1Q2	Cyclohexyl 6-mercaptopicolinate	Investigative	44445243	C12H15NO2S	237.32	C1CCC(CC1)OC(=O)C2=CC=CC(=S)N2	IC50 = 91000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BNU1Q2	Cyclohexyl 6-mercaptopicolinate	Investigative	44445243	C12H15NO2S	237.32	C1CCC(CC1)OC(=O)C2=CC=CC(=S)N2	IC50 = 102000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BNYG94	(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(2-fluorophenylamino)-5-oxopentanoic acid	Investigative	44582645	C22H23FN2O6	430.4	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=CC=C2F)OC	IC50 = 71400 nM	Poor binder
T80942	Matrix metalloproteinase 2	BO2DW9	(R)-4-(4-Carboxy-2-(3,4,5-trimethoxybenzamido)butanamido)benzoic acid	Investigative	44582904	C22H24N2O9	460.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)C(=O)O	IC50 = 71200 nM	Poor binder
T80942	Matrix metalloproteinase 13	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BO54DN	N-[1-(Phenylthiomethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid	Investigative	21700038	C23H20N2O3S	404.5	C1=CC=C(C=C1)SCC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O	IC50 = 160000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BO5DJ0	N'-[2-(3-Methyl-2-oxo-quinoxalin-1-yl)acetyl]-2-phenyl-acetohydrazide	Investigative	46212112	C19H18N4O3	350.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NNC(=O)CC3=CC=CC=C3	IC50 = 159390 nM	Poor binder
T80942	Matrix metalloproteinase 13	BO81HC	Thiadiazole derivative, 33	Investigative	24754176	C23H19N3O2S	401.5	COC1=CC=C(C=C1)C2=NNC3(S2)C4=CC=CC=C4N(C3=O)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BO8W7V	N-Hydroxy-N-[2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl-1-[(4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl]ethyl]formamide	Investigative	9871305	C22H24F3NO8S	519.5	C[C@H]1[C@@H](OC(O1)(C)C)C(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BO9J4I	(2S)-2-[[(2R)-2-Amino-3-methylbutanoyl]amino]-N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	44356789	C27H38N4O3	466.6	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)[C@@H](C(C)C)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BO9W8V	N-Benzyl-2-[1-cyclohexylmethyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328279	C31H36N4O5	544.6	C1CCC(CC1)CN(CC(=O)N(CC2=CC=CC=C2)CC(=O)NO)C(=O)NC3=CC=C(C=C3)OC4=CC=CC=C4	IC50 = 125000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BO9WE6	4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole	Investigative	44445273	C12H20N4O	236.31	CCCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BO9WE6	4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole	Investigative	44445273	C12H20N4O	236.31	CCCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BO9WE6	4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole	Investigative	44445273	C12H20N4O	236.31	CCCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BO9WE6	4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole	Investigative	44445273	C12H20N4O	236.31	CCCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BO9WL8	(4s)-3-{[4-(4-Cyano-2-Methylphenyl)piperazin-1-Yl]sulfonyl}-N-Hydroxy-1,3-Thiazolidine-4-Carboxamide	Investigative	117094707	C16H21N5O4S2	411.5	CC1=C(C=CC(=C1)C#N)N2CCN(CC2)S(=O)(=O)N3CSC[C@@H]3C(=O)NO	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BOC1P3	[(3-Nitroanilino)-phosphono-methyl]phosphonic acid	Investigative	5277490	C7H10N2O8P2	312.11	C1=CC(=CC(=C1)[N+](=O)[O-])NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BOC1P3	[(3-Nitroanilino)-phosphono-methyl]phosphonic acid	Investigative	5277490	C7H10N2O8P2	312.11	C1=CC(=CC(=C1)[N+](=O)[O-])NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BOC1P3	[(3-Nitroanilino)-phosphono-methyl]phosphonic acid	Investigative	5277490	C7H10N2O8P2	312.11	C1=CC(=CC(=C1)[N+](=O)[O-])NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BOE7D4	4-(5-(Biphenyl-3-yl)-4-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485502	C22H16BrN5	430.3	C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C(C=C(N3)C4=NC=CC5=C4N=C(N5)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BOK9I1	N-[(2S,4S)-4-(5-Fluoropyrimidin-2-yl)-2-methyl-1-[4-[2-[3-methyl-5-(trifluoromethyl)pyridin-2-yl]ethyl]piperidin-1-yl]sulfonylpentan-2-yl]-N-hydroxyformamide	Investigative	53326761	C25H33F4N5O4S	575.6	CC1=CC(=CN=C1CCC2CCN(CC2)S(=O)(=O)C[C@](C)(C[C@H](C)C3=NC=C(C=N3)F)N(C=O)O)C(F)(F)F	IC50 ~ 79000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BOL2C9	N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide	Investigative	10610500	C6H9N5O2S2	247.3	CNC(=O)CNC(=O)NC1=NNC(=S)S1	Ki = 165958.69 nM	Poor binder
T80942	Matrix metalloproteinase 1	BOL2C9	N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide	Investigative	10610500	C6H9N5O2S2	247.3	CNC(=O)CNC(=O)NC1=NNC(=S)S1	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BOL2C9	N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide	Investigative	10610500	C6H9N5O2S2	247.3	CNC(=O)CNC(=O)NC1=NNC(=S)S1	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BOLF53	4-(4,5-Dibromo-3-phenethyl-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485477	C18H15Br2N5	461.2	C1=CC=C(C=C1)CCC2=C(NC(=C2Br)Br)C3=NC=CC4=C3N=C(N4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BORP07	5-(3-Pyridylmethyl)-1H-tetrazole	Investigative	28602444	C7H7N5	161.16	C1=CC(=CN=C1)CC2=NNN=N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BORP07	5-(3-Pyridylmethyl)-1H-tetrazole	Investigative	28602444	C7H7N5	161.16	C1=CC(=CN=C1)CC2=NNN=N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BORP07	5-(3-Pyridylmethyl)-1H-tetrazole	Investigative	28602444	C7H7N5	161.16	C1=CC(=CN=C1)CC2=NNN=N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BOVG57	{(R)-3-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-5-methyl-hexanoylaminooxy}-acetic acid methyl ester	Investigative	10647658	C23H32N4O6	460.5	CC(C)C[C@H](CC(=O)NOCC(=O)OC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC	Ki = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BOZJ91	N-Hydroxy-N-{3-hydroxy-2-hydroxymethyl-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide	Investigative	10961828	C19H20F3NO8S	479.4	C1=CC(=CC=C1OC2=CC=C(C=C2)S(=O)(=O)CC(C(CO)CO)N(C=O)O)OC(F)(F)F	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BP0K8E	N-Hydroxy-N-{1-(tetrahydro-furan-2-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	9826199	C20H20F3NO7S	475.4	C1CC(OC1)C(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BP4CV9	3-(3,4-Dimethoxyphenyl)-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]oxypropanoic acid	Investigative	71654518	C21H22O6	370.4	CC1=CC=C(C=C1)/C=C/C(=O)OC(CC2=CC(=C(C=C2)OC)OC)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BP50JB	Antibiotic A 26771B	Investigative	11143436	C20H30O7	382.4	C[C@@H]1CCCCCCCCC[C@@H](C(=O)/C=C/C(=O)O1)OC(=O)CCC(=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BP53DZ	(S)-2-((R)-2-Acetylamino-3-mercapto-propionylamino)-3-phenyl-propionamide	Investigative	44299709	C14H19N3O3S	309.39	CC(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BP5Y8B	[2-(2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-p-tolyl-pentyl]-phosphonic acid	Investigative	10414974	C30H43N2O5P	542.6	CC1=CC=C(C=C1)CCC[C@H](CP(=O)(O)O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCC3=CC=CC=C3	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BP6ED9	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036777	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC(=CC=C4)[N+](=O)[O-])/S3	IC50 = 55880 nM	Poor binder
T80942	Matrix metalloproteinase 3	BP6ED9	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036777	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC(=CC=C4)[N+](=O)[O-])/S3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BP6NW4	(Cyclobutylamino)carbonylphosphonic acid	Investigative	11194666	C5H10NO4P	179.11	C1CC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BP6NW4	(Cyclobutylamino)carbonylphosphonic acid	Investigative	11194666	C5H10NO4P	179.11	C1CC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BP6NW4	(Cyclobutylamino)carbonylphosphonic acid	Investigative	11194666	C5H10NO4P	179.11	C1CC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BP7Q2C	(R)-5-(3-Chloro-4-fluorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582547	C21H22ClFN2O7	468.9	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC(=C(C=C2)F)Cl	IC50 = 107200 nM	Poor binder
T80942	Matrix metalloproteinase 9	BP80KT	N-(3-(1-Tert-butylpiperidin-4-yl)-1-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)propan-2-yl)-N-hydroxyformamide	Investigative	44429877	C30H39N3O5S	553.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(CC4CCN(CC4)C(C)(C)C)N(C=O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BP9QX0	(R)-5-(2,5-Dichlorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582907	C21H22Cl2N2O7	485.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=C(C=CC(=C2)Cl)Cl	IC50 = 122400 nM	Poor binder
T80942	Matrix metalloproteinase 2	BPJ18L	(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2S)-3-amino-2-hydroxypropanoyl]amino]-4-methylpentanamide	Investigative	56682179	C18H29N5O6	411.5	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)[N+](=O)[O-])O)N)NC(=O)[C@H](CN)O	IC50 = 83900 nM	Poor binder
T80942	Matrix metalloproteinase 1	BPJ4S9	N-Hydroxy-N-{3-(4-methanesulfonyl-piperazin-1-yl)-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide	Investigative	10282084	C23H28F3N3O8S2	595.6	CS(=O)(=O)N1CCN(CC1)CCC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BPJ60S	(2S)-2-Amino-3-thiol-N-[(2R)-2-amino-3-phenylpropyl]propionamide	Investigative	44588253	C12H19N3OS	253.37	C1=CC=C(C=C1)C[C@H](CNC(=O)[C@H](CS)N)N	IC50 = 78800 nM	Poor binder
T80942	Matrix metalloproteinase 12	BPM2J0	3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445209	C14H13NO4	259.26	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BPM2J0	3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445209	C14H13NO4	259.26	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BPM2J0	3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445209	C14H13NO4	259.26	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BPM2J0	3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445209	C14H13NO4	259.26	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 88000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BPQ3E1	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylmethyl)-ethyl]-formamide	Investigative	44330149	C27H30N2O6S	510.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(CC4CCC(=O)CC4)N(C=O)O	IC50 = 53000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BPW80Z	2-(4''-Cyano-biphenyl-4-sulfonylamino)-N-hydroxy-3-methyl-butyramide	Investigative	10523383	C18H19N3O4S	373.4	CC(C)[C@@H](C(=O)NO)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)C#N	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BPWS17	N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-indan-1-yl-succinamide	Investigative	15524387	C20H22N2O4	354.4	C1CC2=CC=CC=C2[C@@H]1NC(=O)[C@H](CC3=CC=C(C=C3)O)CC(=O)NO	Ki = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BQ07HA	(2s)-6-[(4-Fluorobenzyl)amino]-2-[(2r)-2-(4-Fluorophenyl)-2-Methoxyethyl]-N-Hydroxyhexanamide	Investigative	54582019	C22H28F2N2O3	406.5	CO[C@H](C[C@H](CCCCNCC1=CC=C(C=C1)F)C(=O)NO)C2=CC=C(C=C2)F	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BQ07HA	(2s)-6-[(4-Fluorobenzyl)amino]-2-[(2r)-2-(4-Fluorophenyl)-2-Methoxyethyl]-N-Hydroxyhexanamide	Investigative	54582019	C22H28F2N2O3	406.5	CO[C@H](C[C@H](CCCCNCC1=CC=C(C=C1)F)C(=O)NO)C2=CC=C(C=C2)F	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQ2HP5	N-[4-[4-(Thiiran-2-ylmethylsulfonyl)phenoxy]phenyl]acetamide	Investigative	15941553	C17H17NO4S2	363.5	CC(=O)NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)CC3CS3	Ki = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BQ8A6D	(2R)-2-[(Biphenyl-4-ylcarbonyl)amino]-3-phenylpropanoic acid	Investigative	10617505	C22H19NO3	345.4	C1=CC=C(C=C1)C[C@H](C(=O)O)NC(=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQ97ZC	3,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445218	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=CC(=C2)F)F	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BQ97ZC	3,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445218	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=CC(=C2)F)F	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BQ9P2T	5-(Benzylamino)-1,3,4-thiadiazole-2-thiol	Investigative	830422	C9H9N3S2	223.3	C1=CC=C(C=C1)CNC2=NNC(=S)S2	IC50 = 97000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BQH92J	N-{2,3-Dihydroxy-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-N-hydroxy-formamide	Investigative	44314322	C18H18F3NO8S	465.4	C1=CC(=CC=C1OC2=CC=C(C=C2)S(=O)(=O)CC([C@@H](CO)O)N(C=O)O)OC(F)(F)F	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQI1T0	(3R)-6-Cyclohexyl-N-hydroxy-3-[3-(3-pyridinylmethyl)-1,2,4-oxadiazol-5-yl]hexanamide	Investigative	16748901	C20H28N4O3	372.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)CC3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQK5W3	4-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445252	C14H13NO3S	275.32	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 91000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BQK5W3	4-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445252	C14H13NO3S	275.32	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 95000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BQK5W3	4-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445252	C14H13NO3S	275.32	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 96000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BQK5W3	4-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445252	C14H13NO3S	275.32	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 108000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BQK86U	1-(4-Chloro-2-methyl-phenyl)-3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-urea	Investigative	44285342	C10H9ClN4OS2	300.8	CC1=C(C=CC(=C1)Cl)NC(=O)NC2=NNC(=S)S2	Ki = 119000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQKA74	Ethyl 5-(5-methoxycarbonyl-2-methylpyrazol-3-yl)-1H-indole-2-carboxylate	Investigative	56850409	C17H17N3O4	327.33	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C3=CC(=NN3C)C(=O)OC	IC50 = 83000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BQM30A	N-[(2S,4S)-1-[4-[2-[2-Chloro-4-(trifluoromethyl)phenyl]ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide	Investigative	53325497	C25H31ClF4N4O4S	595	C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CC1)CCC2=C(C=C(C=C2)C(F)(F)F)Cl)N(C=O)O)C3=NC=C(C=N3)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQN7T5	N-[1-[4-(4-Cyanophenyl)phenoxy]propan-2-yl]-N-hydroxyformamide	Investigative	10402302	C17H16N2O3	296.32	CC(COC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)N(C=O)O	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BQRJ21	(2S,4R)-4-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-2-methyl-6-phenyl-hexanoic acid	Investigative	44294877	C25H32N2O5	440.5	C[C@@H](C[C@@H](CCC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OC)C(=O)NC)C(=O)O	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BQX1W6	Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445228	C15H13NO3	255.27	C1=CC=C(C=C1)/C=C/COC(=O)C2=CC=CC(=O)N2	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BQX1W6	Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445228	C15H13NO3	255.27	C1=CC=C(C=C1)/C=C/COC(=O)C2=CC=CC(=O)N2	IC50 = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BQX1W6	Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445228	C15H13NO3	255.27	C1=CC=C(C=C1)/C=C/COC(=O)C2=CC=CC(=O)N2	IC50 = 86000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BQX1W6	Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445228	C15H13NO3	255.27	C1=CC=C(C=C1)/C=C/COC(=O)C2=CC=CC(=O)N2	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BQXF82	Ethyl 2-(hydroxycarbamoyl)-4-phenylbutanoate	Investigative	10800736	C13H17NO4	251.28	CCOC(=O)C(CCC1=CC=CC=C1)C(=O)NO	Ki = 189000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BR0S8L	5-Methyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione	Investigative	1836	C17H14N2O4	310.3	CC1(C(=O)NC(=O)NC1=O)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BR28PO	Chembl4163839	Investigative	145959777	C18H19N3O7S	421.4	C1=CC=C(C=C1)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 95200 nM	Poor binder
T80942	Matrix metalloproteinase 14	BR28PO	Chembl4163839	Investigative	145959777	C18H19N3O7S	421.4	C1=CC=C(C=C1)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 109000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BR28PO	Chembl4163839	Investigative	145959777	C18H19N3O7S	421.4	C1=CC=C(C=C1)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 172800 nM	Poor binder
T80942	Matrix metalloproteinase 9	BR2VF9	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	10437629	C30H39N3O5S	553.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(CC4CCN(CC4)CC(C)C)N(C=O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BR64OE	Chembl4212208	Investigative	57874709	C22H18F3NO4S2	481.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)SC3=CC=CC=C3CC(=O)NS(=O)(=O)C(F)(F)F	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BR6BS8	N-[4-[[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonylmethyl]oxan-4-yl]-N-hydroxyformamide	Investigative	54580051	C21H33N3O5S	439.6	CC1=CC(=C(C=N1)C)CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(C=O)O	IC50 = 61000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BR6BS8	N-[4-[[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonylmethyl]oxan-4-yl]-N-hydroxyformamide	Investigative	54580051	C21H33N3O5S	439.6	CC1=CC(=C(C=N1)C)CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BR6BS8	N-[4-[[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonylmethyl]oxan-4-yl]-N-hydroxyformamide	Investigative	54580051	C21H33N3O5S	439.6	CC1=CC(=C(C=N1)C)CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BRC53V	N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide	Investigative	71682917	C17H19NO4S	333.4	C1C[C@@H]([C@H](C1)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BRC53V	N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide	Investigative	71682917	C17H19NO4S	333.4	C1C[C@@H]([C@H](C1)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BRC53V	N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide	Investigative	71682917	C17H19NO4S	333.4	C1C[C@@H]([C@H](C1)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BRCZ16	1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445274	C12H12N4O	228.25	C1COC(=N1)C2=CN(N=N2)CC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BRCZ16	1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445274	C12H12N4O	228.25	C1COC(=N1)C2=CN(N=N2)CC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BRCZ16	1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445274	C12H12N4O	228.25	C1COC(=N1)C2=CN(N=N2)CC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BRCZ16	1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445274	C12H12N4O	228.25	C1COC(=N1)C2=CN(N=N2)CC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BRD5Z7	(2r,3r)-4-[4-(2-Chlorophenyl)piperazin-1-Yl]-2,3-Dihydroxy-4-Oxo-N-(2-Thiophen-2-Ylethyl)butanamide	Investigative	11640694	C20H24ClN3O4S	437.9	C1CN(CCN1C2=CC=CC=C2Cl)C(=O)[C@@H]([C@H](C(=O)NCCC3=CC=CS3)O)O	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BRD5Z7	(2r,3r)-4-[4-(2-Chlorophenyl)piperazin-1-Yl]-2,3-Dihydroxy-4-Oxo-N-(2-Thiophen-2-Ylethyl)butanamide	Investigative	11640694	C20H24ClN3O4S	437.9	C1CN(CCN1C2=CC=CC=C2Cl)C(=O)[C@@H]([C@H](C(=O)NCCC3=CC=CS3)O)O	Ki ~ 60000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BRD5Z7	(2r,3r)-4-[4-(2-Chlorophenyl)piperazin-1-Yl]-2,3-Dihydroxy-4-Oxo-N-(2-Thiophen-2-Ylethyl)butanamide	Investigative	11640694	C20H24ClN3O4S	437.9	C1CN(CCN1C2=CC=CC=C2Cl)C(=O)[C@@H]([C@H](C(=O)NCCC3=CC=CS3)O)O	Ki ~ 90000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BRFY07	3-(Trifluoromethyl)benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445207	C14H10F3NO3	297.23	C1=CC(=CC(=C1)C(F)(F)F)COC(=O)C2=CC=CC(=O)N2	IC50 = 82000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BRI81Y	CID 10874819	Investigative	10874819	C21H22F3NO8S	505.5	CC1(OC[C@H](O1)[C@@H](CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BRLS26	(R)-2-(N-Benzyl-4-(2-fluoroethoxy)phenylsulphonamido)-3-methylbutanoic acid	Investigative	23655717	C20H24FNO5S	409.5	CC(C)[C@H](C(=O)O)N(CC1=CC=CC=C1)S(=O)(=O)C2=CC=C(C=C2)OCCF	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BRTE39	Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445231	C14H11NO5	273.24	C1OC2=C(O1)C=C(C=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 105000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BRTE39	Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445231	C14H11NO5	273.24	C1OC2=C(O1)C=C(C=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 107000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BRTE39	Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445231	C14H11NO5	273.24	C1OC2=C(O1)C=C(C=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 114000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BRTE39	Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445231	C14H11NO5	273.24	C1OC2=C(O1)C=C(C=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 128000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BS17YT	(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(2-methoxy-2-oxoethylamino)-5-oxopentanoic acid	Investigative	44582717	C19H24N2O8	408.4	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)OC)OC	IC50 = 79600 nM	Poor binder
T80942	Matrix metalloproteinase 7	BS1DV9	N-[(1S,2S)-2-Sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682913	C11H15NO2S2	257.399	C1C[C@@H]([C@H](C1)S)NS(=O)(=O)C2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BS25YO	N-Sec-Butyl-2-[1-butyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44327961	C25H34N4O5	470.6	CCCCN(CC(=O)N(CC(=O)NO)C(C)CC)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 54000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BS2M5I	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-benzylidene-1,3-thiazolidin-4-one	Investigative	136036787	C17H11N3OS2	337.4	C1=CC=C(C=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BS2Q0X	N-Hydroxy-N-{1-phenyl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	11038175	C22H18F3NO6S	481.4	C1=CC=C(C=C1)C(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BS42BZ	N-Hydroxy-N-[2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-1-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-ethyl]-formamide	Investigative	11049982	C23H24F3N3O8S	559.5	CC1(C(=O)N(C(=O)N1C)CC(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BS4KA8	Chembl4206956	Investigative	145975682	C33H24O4	484.5	C1=CC=C(C=C1)/C(=C\\C(=O)C2=CC=C(C=C2)O)/C3=C(C=CC=C3C4=CC=C(C=C4)O)C5=CC=C(C=C5)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BS4KA8	Chembl4206956	Investigative	145975682	C33H24O4	484.5	C1=CC=C(C=C1)/C(=C\\C(=O)C2=CC=C(C=C2)O)/C3=C(C=CC=C3C4=CC=C(C=C4)O)C5=CC=C(C=C5)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BS6RN3	[(R)-2-Methyl-1-(4-phenethyl-benzenesulfonylamino)-propyl]-phosphonic acid	Investigative	44422744	C18H24NO5PS	397.4	CC(C)[C@H](NS(=O)(=O)C1=CC=C(C=C1)CCC2=CC=CC=C2)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BS81KI	(2S)-2-Amino-N-[(3S)-1-[2-(4-bromoanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863953	C22H23BrN4O4	487.3	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC=C(C=C3)Br	IC50 = 71600 nM	Poor binder
T80942	Matrix metalloproteinase 1	BS9D5V	3-Hydroxy-5-[4-(4-methylsulfanylphenyl)phenyl]pentanoic acid	Investigative	44626353	C18H20O3S	316.4	CSC1=CC=C(C=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BSD4C0	Cyclobutyl 6-mercaptopicolinate	Investigative	44445242	C10H11NO2S	209.27	C1CC(C1)OC(=O)C2=CC=CC(=S)N2	IC50 = 135000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BSD4C0	Cyclobutyl 6-mercaptopicolinate	Investigative	44445242	C10H11NO2S	209.27	C1CC(C1)OC(=O)C2=CC=CC(=S)N2	IC50 = 137000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BSD4C0	Cyclobutyl 6-mercaptopicolinate	Investigative	44445242	C10H11NO2S	209.27	C1CC(C1)OC(=O)C2=CC=CC(=S)N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BSD4C0	Cyclobutyl 6-mercaptopicolinate	Investigative	44445242	C10H11NO2S	209.27	C1CC(C1)OC(=O)C2=CC=CC(=S)N2	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BSD50Z	4-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445250	C14H10F3NO2S	313.3	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BSD50Z	4-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445250	C14H10F3NO2S	313.3	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 125000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BSD50Z	4-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445250	C14H10F3NO2S	313.3	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 141000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BSD50Z	4-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445250	C14H10F3NO2S	313.3	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BSJ45U	Morpholin-4-ylcarbonylphosphonic acid	Investigative	44328189	C5H10NO5P	195.11	C1COCCN1C(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BSJ45U	Morpholin-4-ylcarbonylphosphonic acid	Investigative	44328189	C5H10NO5P	195.11	C1COCCN1C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BSJ45U	Morpholin-4-ylcarbonylphosphonic acid	Investigative	44328189	C5H10NO5P	195.11	C1COCCN1C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BSK02N	2-(5-(4-(Benzyloxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid	Investigative	1383990	C19H15NO4S2	385.5	C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C\\3/C(=O)N(C(=S)S3)CC(=O)O	IC50 = 58500 nM	Poor binder
T80942	Matrix metalloproteinase 12	BSM73K	4-(4-Bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	44426071	C10H8BrN5	278.11	C1=CN=C(C2=C1NC(=N2)N)C3=CC(=CN3)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BSP3A8	Schembl22225166	Investigative	17853548	C17H20O9	368.3	COC(=O)C1(CC(C(C(C1)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O)O	IC50 = 58810 nM	Poor binder
T80942	Matrix metalloproteinase 2	BSP3A8	Schembl22225166	Investigative	17853548	C17H20O9	368.3	COC(=O)C1(CC(C(C(C1)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O)O	IC50 = 64190 nM	Poor binder
T80942	Matrix metalloproteinase 3	BSRZ86	Cyclopentylcarbamoylphosphonic Acid	Investigative	10198038	C6H12NO4P	193.14	C1CCC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BSRZ86	Cyclopentylcarbamoylphosphonic Acid	Investigative	10198038	C6H12NO4P	193.14	C1CCC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BSRZ86	Cyclopentylcarbamoylphosphonic Acid	Investigative	10198038	C6H12NO4P	193.14	C1CCC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BSW74J	(4S)-5-Amino-4-[[(2S)-4-methyl-2-[3-[4-(4-phenylphenyl)phenyl]propanoylamino]pentanoyl]amino]-5-oxopentanoic acid	Investigative	50991333	C32H37N3O5	543.7	CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N)NC(=O)CCC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BSX0L7	3-(3,4-Dimethoxyphenyl)-2-[(E)-3-(4-methoxyphenyl)prop-2-enoyl]oxypropanoic acid	Investigative	71652359	C21H22O7	386.4	COC1=CC=C(C=C1)/C=C/C(=O)OC(CC2=CC(=C(C=C2)OC)OC)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BT05YX	(2S)-N-[(2S)-1-Oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenyl-2-(quinolin-8-ylsulfonylamino)propanamide	Investigative	90663081	C23H22N6O4S3	542.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)C3=CC=CC4=C3N=CC=C4	Ki = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BT12UN	2-{Isopropoxy[(4-methoxyphenyl)sulfonyl]amino}-N-hydroxyacetamide	Investigative	44423677	C12H18N2O6S	318.35	CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)OC	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BT13RF	6-(4-Chloro-phenyl)-3-{2-cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-hexanoic acid	Investigative	44314970	C30H40ClN3O6S	606.2	C1CCC(CC1)C[C@@H](C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N)NC(=O)[C@H](CCCC3=CC=C(C=C3)Cl)CC(=O)O	Ki = 54954.09 nM	Poor binder
T80942	Matrix metalloproteinase 12	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 17	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BT17QX	Lithium ethyl (cyclohexylamino)carbonylphosphonate	Investigative	53322469	C9H17LiNO4P	241.2	[Li+].CCOP(=O)(C(=O)NC1CCCCC1)[O-]	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BT17QX	Lithium ethyl (cyclohexylamino)carbonylphosphonate	Investigative	53322469	C9H17LiNO4P	241.2	[Li+].CCOP(=O)(C(=O)NC1CCCCC1)[O-]	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BT17QX	Lithium ethyl (cyclohexylamino)carbonylphosphonate	Investigative	53322469	C9H17LiNO4P	241.2	[Li+].CCOP(=O)(C(=O)NC1CCCCC1)[O-]	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BT1Q5P	(5-Chloro-3,4-dihydro-1H-2,1,3-benzothiadiazine-3-acetohydroxamic acid)2,2-dioxide	Investigative	10732349	C9H10ClN3O4S	291.71	C1C2=C(C=CC=C2Cl)NS(=O)(=O)N1CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BT2BH7	N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	10972891	C21H17F3N2O6S	482.4	C1=CC=NC(=C1)C(CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC(F)(F)F)N(C=O)O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BT4QP5	4-(5-Bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	44426072	C10H8BrN5	278.11	C1=CN=C(C2=C1NC(=N2)N)C3=CC=C(N3)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BT61GW	4-{[1-Methyl-2,4-Dioxo-6-(3-Phenylprop-1-Yn-1-Yl)-1,4-Dihydroquinazolin-3(2h)-Yl]methyl}benzoic Acid	Investigative	10224181	C26H20N2O4	424.4	CN1C2=C(C=C(C=C2)C#CCC3=CC=CC=C3)C(=O)N(C1=O)CC4=CC=C(C=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BT61GW	4-{[1-Methyl-2,4-Dioxo-6-(3-Phenylprop-1-Yn-1-Yl)-1,4-Dihydroquinazolin-3(2h)-Yl]methyl}benzoic Acid	Investigative	10224181	C26H20N2O4	424.4	CN1C2=C(C=C(C=C2)C#CCC3=CC=CC=C3)C(=O)N(C1=O)CC4=CC=C(C=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BT61GW	4-{[1-Methyl-2,4-Dioxo-6-(3-Phenylprop-1-Yn-1-Yl)-1,4-Dihydroquinazolin-3(2h)-Yl]methyl}benzoic Acid	Investigative	10224181	C26H20N2O4	424.4	CN1C2=C(C=C(C=C2)C#CCC3=CC=CC=C3)C(=O)N(C1=O)CC4=CC=C(C=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 10	BTE1R5	N-Phenyl-4-[(4h-1,2,4-Triazol-3-Ylsulfanyl)methyl]-1,3-Thiazol-2-Amine	Investigative	2366268	C12H11N5S2	289.4	C1=CC=C(C=C1)NC2=NC(=CS2)CSC3=NC=NN3	IC50 = 83000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BTE3R6	(2E)-3-(N-Hydroxycarbamoyl)-2-heptylidenepropionyl-L-tryptophan-N-methylamide	Investigative	44434565	C23H32N4O4	428.5	CCCCCC/C=C(\\CC(=O)NO)/C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BTE3R6	(2E)-3-(N-Hydroxycarbamoyl)-2-heptylidenepropionyl-L-tryptophan-N-methylamide	Investigative	44434565	C23H32N4O4	428.5	CCCCCC/C=C(\\CC(=O)NO)/C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BTE7I6	6-Mercapto-pyridine-2-carboxylic acid biphenyl-3-ylmethyl ester	Investigative	44445266	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=CC(=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BTE7I6	6-Mercapto-pyridine-2-carboxylic acid biphenyl-3-ylmethyl ester	Investigative	44445266	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=CC(=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BTE7I6	6-Mercapto-pyridine-2-carboxylic acid biphenyl-3-ylmethyl ester	Investigative	44445266	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=CC(=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BTE9Q1	N-(4-Amino-2-methylquinolin-6-yl)-4-quinolin-8-ylbenzamide	Investigative	73055905	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)C4=CC=CC5=C4N=CC=C5)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BTOX16	(2S)-N-Hydroxy-1-[(3S)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl]pyrrolidine-2-carboxamide;hydrochloride	Investigative	56677119	C15H20ClN3O3	325.79	C1C[C@H](N(C1)C(=O)[C@@H]2CC3=CC=CC=C3CN2)C(=O)NO.Cl	IC50 = 157420 nM	Poor binder
T80942	Matrix metalloproteinase 14	BTP5Y8	(2S)-2-[(2R)-2-(4-Fluorophenyl)-2-methoxyethyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345502	C24H32F2N2O3	434.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](C[C@H](C2=CC=C(C=C2)F)OC)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BTQF19	N'-[2-(3-Methyl-2-oxo-quinoxalin-1-yl)acetyl]benzohydrazide	Investigative	46212861	C18H16N4O3	336.3	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NNC(=O)C3=CC=CC=C3	IC50 = 187410 nM	Poor binder
T80942	Matrix metalloproteinase 1	BTV5U3	4-Cyano-N-(2-piperidin-1-yl-phenyl)-benzamide	Investigative	7550925	C19H19N3O	305.4	C1CCN(CC1)C2=CC=CC=C2NC(=O)C3=CC=C(C=C3)C#N	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BTVA75	N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-methoxy-benzyl)-succinamide	Investigative	15524389	C21H24N2O5	384.4	COC1=CC=CC(=C1)C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@@H](CC3=CC=CC=C23)O	Ki = 95500 nM	Poor binder
T80942	Matrix metalloproteinase 14	BTWA58	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-methoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	10462640	C38H41N4O7PS	728.8	COC1=CC=CC=C1SCC(CP(=O)(C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)O)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N	Ki = 160000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BTZ16E	N4-(4-Chlorophenyl)-2-cinnamamido-N1-hydroxysuccinamide	Investigative	46228308	C19H18ClN3O4	387.8	C1=CC=C(C=C1)/C=C/C(=O)N[C@H](CC(=O)NC2=CC=C(C=C2)Cl)C(=O)NO	IC50 = 196600 nM	Poor binder
T80942	Matrix metalloproteinase 1	BU5E3S	3-(3,4-Dimethoxyphenyl)-2-[(E)-3-naphthalen-2-ylprop-2-enoyl]oxypropanoic acid	Investigative	71652362	C24H22O6	406.4	COC1=C(C=C(C=C1)CC(C(=O)O)OC(=O)/C=C/C2=CC3=CC=CC=C3C=C2)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BU5T8R	(1R,2S,5R)-2-[4-(4-Chlorophenyl)phenyl]sulfanyl-5-[(4-oxo-1,2,3-benzotriazin-3-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	9891814	C26H22ClN3O3S	492	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)SC4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BU72GZ	N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride	Investigative	71680867	C22H30ClN3O5S	484	C1[C@@H]([C@H](CN1C(=O)CCCCCN)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BU72GZ	N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride	Investigative	71680867	C22H30ClN3O5S	484	C1[C@@H]([C@H](CN1C(=O)CCCCCN)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BU72GZ	N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride	Investigative	71680867	C22H30ClN3O5S	484	C1[C@@H]([C@H](CN1C(=O)CCCCCN)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BU72GZ	N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride	Investigative	71680867	C22H30ClN3O5S	484	C1[C@@H]([C@H](CN1C(=O)CCCCCN)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BU7EQ0	(2R)-2-Amino-N-[(2S)-1-[[(2S)-1-(benzylamino)-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methylpentanamide	Investigative	44356688	C30H41N5O3	519.7	CC(C)C[C@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(C)C)C(=O)NCC3=CC=CC=C3)N	IC50 ~ 60000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BU86KW	[[4-(4-Chlorophenoxy)anilino]-phosphonomethyl]phosphonic acid	Investigative	72205114	C13H14ClNO7P2	393.65	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)OC2=CC=C(C=C2)Cl	IC50 = 55000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BU86KW	[[4-(4-Chlorophenoxy)anilino]-phosphonomethyl]phosphonic acid	Investigative	72205114	C13H14ClNO7P2	393.65	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)OC2=CC=C(C=C2)Cl	IC50 = 76000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BU97NY	(2R,3R)-N-(Benzofuran-2-ylmethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide	Investigative	11517085	C23H24N2O5	408.4	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCC2=CC3=CC=CC=C3O2)O)O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BUE50B	2-(3-Methyl-2-oxoquinoxalin-1-yl)-N-[(E)-1-(4-nitrophenyl)ethylideneamino]acetamide	Investigative	127031462	C19H17N5O4	379.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C(\\C)/C3=CC=C(C=C3)[N+](=O)[O-]	IC50 = 90810 nM	Poor binder
T80942	Matrix metalloproteinase 1	BUHO01	3-(1-Carbamoyl-2-cyclohexyl-ethylcarbamoyl)-6-phenyl-hexanoic acid	Investigative	44314995	C22H32N2O4	388.5	C1CCC(CC1)C[C@@H](C(=O)N)NC(=O)[C@H](CCCC2=CC=CC=C2)CC(=O)O	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BUK1T6	3-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445249	C14H10F3NO2S	313.3	C1=CC(=CC(=C1)C(F)(F)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 110000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BUK1T6	3-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445249	C14H10F3NO2S	313.3	C1=CC(=CC(=C1)C(F)(F)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 126000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BUK1T6	3-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445249	C14H10F3NO2S	313.3	C1=CC(=CC(=C1)C(F)(F)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 134000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BUK1T6	3-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445249	C14H10F3NO2S	313.3	C1=CC(=CC(=C1)C(F)(F)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 134000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BUO20M	[Phosphono-[3-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204934	C8H10F3NO6P2	335.11	C1=CC(=CC(=C1)NC(P(=O)(O)O)P(=O)(O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BUO20M	[Phosphono-[3-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204934	C8H10F3NO6P2	335.11	C1=CC(=CC(=C1)NC(P(=O)(O)O)P(=O)(O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BUO20M	[Phosphono-[3-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204934	C8H10F3NO6P2	335.11	C1=CC(=CC(=C1)NC(P(=O)(O)O)P(=O)(O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BUX9C2	Chembl4218730	Investigative	145969859	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)OC)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)OC	IC50 = 51900 nM	Poor binder
T80942	Matrix metalloproteinase 8	BUX9C2	Chembl4218730	Investigative	145969859	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)OC)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)OC	IC50 = 55100 nM	Poor binder
T80942	Matrix metalloproteinase 2	BV0CE6	Methyl (E)-5-(4-hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxopent-4-enoate	Investigative	49806133	C21H18O6	366.4	COC(=O)C(C(=O)/C=C/C1=CC=C(C=C1)O)C(=O)/C=C/C2=CC=C(C=C2)O	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BV0CJ9	4-Phenoxy-N-[(1R,2R)-2-sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682916	C17H19NO3S2	349.5	C1C[C@H]([C@@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BV1HA4	Hydroxysulfonamide 48	Investigative	23644663	CH2Cl3NO3S	214.5	C(S(=O)(=O)NO)(Cl)(Cl)Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BV1HA4	Hydroxysulfonamide 48	Investigative	23644663	CH2Cl3NO3S	214.5	C(S(=O)(=O)NO)(Cl)(Cl)Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BV1HA4	Hydroxysulfonamide 48	Investigative	23644663	CH2Cl3NO3S	214.5	C(S(=O)(=O)NO)(Cl)(Cl)Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BV1HA4	Hydroxysulfonamide 48	Investigative	23644663	CH2Cl3NO3S	214.5	C(S(=O)(=O)NO)(Cl)(Cl)Cl	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BV1SF0	N-Hydroxycarbamoylmethyl-2-[1-(1-methyl-butyl)-3-(4-phenoxy-phenyl)-ureido]-N-pentyl-acetamide	Investigative	44327939	C27H38N4O5	498.6	CCCCCN(CC(=O)NO)C(=O)CN(C(C)CCC)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 160000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BV3LN7	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-(4-hydroxyphenyl)propanamide	Investigative	56682178	C18H22N4O5	374.4	C1=CC(=CC=C1C[C@@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N)O	IC50 = 61300 nM	Poor binder
T80942	Matrix metalloproteinase 1	BV7YC8	3-Hydroxy-5-[4-(4-phenoxyphenyl)phenyl]pentanoic acid	Investigative	45483023	C23H22O4	362.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=CC=C(C=C3)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BV84GE	N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(2-chlorophenyl)methyl]-2-phenoxyacetamide	Investigative	3671894	C24H18Cl2N2O3	453.3	C1=CC=C(C=C1)OCC(=O)NC(C2=CC=CC=C2Cl)C3=CC(=C4C=CC=NC4=C3O)Cl	IC50 ~ 67000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BVA15M	Dipotassium;2-[[(2S)-2-[[(2S)-2-[[ethoxy(oxido)phosphoryl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetate	Investigative	14505615	C13H24K2N3O7P	443.52	CCOP(=O)(N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)[O-])[O-].[K+].[K+]	Ki = 140000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BVAB51	Chembl4214656	Investigative	145972990	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BVAB51	Chembl4214656	Investigative	145972990	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BVAB51	Chembl4214656	Investigative	145972990	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BVBQ62	2,6-Dichloro-N'-[2-(3-methyl-2-oxo-quinoxalin-1-yl)acetyl]benzohydrazide	Investigative	46212114	C18H14Cl2N4O3	405.2	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NNC(=O)C3=C(C=CC=C3Cl)Cl	IC50 = 58220 nM	Poor binder
T80942	Matrix metalloproteinase 9	BVD3H6	N-(4'-Cyano-1,1'-biphenyl-4-ylsulfonyl)valine	Investigative	10594564	C18H18N2O4S	358.4	CC(C)[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)C#N	IC50 = 58884.37 nM	Poor binder
T80942	Matrix metalloproteinase 2	BVI84X	(2S)-N-[(2S,3S)-2-Amino-3-(4-aminophenyl)-3-hydroxypropyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	56678975	C24H35N5O3	441.6	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)N)O)N)NC(=O)[C@@H](CC2=CC=CC=C2)N	IC50 = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BVK7H3	4-(2-Phenylethoxy)-N-(pyridin-4-ylmethyl)benzamide	Investigative	56673549	C21H20N2O2	332.4	C1=CC=C(C=C1)CCOC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BVL83B	N-(2beta-Mercaptocyclopentane-1alpha-yl)-4-phenoxybenzenesulfonamide	Investigative	71682915	C17H19NO3S2	349.5	C1C[C@@H]([C@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BVN52W	4-(4-Bromo-5-phenyl-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485487	C16H12BrN5	354.2	C1=CC=C(C=C1)C2=C(C=C(N2)C3=NC=CC4=C3N=C(N4)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BVQ1A0	Z-D-Trp-OH	Investigative	700663	C19H18N2O4	338.4	C1=CC=C(C=C1)COC(=O)N[C@H](CC2=CNC3=CC=CC=C32)C(=O)O	Ki = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BVQM95	5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-trione	Investigative	44384940	C20H28N2O4	360.4	CCCCCCCCOC1=CC=C(C=C1)CC2(C(=O)NC(=O)NC2=O)C	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BVZ90P	(Isopropylamino)carbonylphosphonic acid	Investigative	11147931	C4H10NO4P	167.1	CC(C)NC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BVZ90P	(Isopropylamino)carbonylphosphonic acid	Investigative	11147931	C4H10NO4P	167.1	CC(C)NC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BVZ90P	(Isopropylamino)carbonylphosphonic acid	Investigative	11147931	C4H10NO4P	167.1	CC(C)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BW0FL1	(2S)-2,6-Diamino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]hexanamide	Investigative	56665194	C15H25N5O4	339.39	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CCCCN)N)N)O)[N+](=O)[O-]	IC50 = 84300 nM	Poor binder
T80942	Matrix metalloproteinase 2	BW1KQ0	4-Phenoxybutyl 6-mercaptopicolinate	Investigative	44445253	C16H17NO3S	303.4	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=S)N2	IC50 = 63000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BW1KQ0	4-Phenoxybutyl 6-mercaptopicolinate	Investigative	44445253	C16H17NO3S	303.4	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=S)N2	IC50 = 78000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BW1KQ0	4-Phenoxybutyl 6-mercaptopicolinate	Investigative	44445253	C16H17NO3S	303.4	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=S)N2	IC50 = 83000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BW1KQ0	4-Phenoxybutyl 6-mercaptopicolinate	Investigative	44445253	C16H17NO3S	303.4	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=S)N2	IC50 = 138000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BW21UB	(2R)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide	Investigative	56682294	C27H31IN4O3	586.5	C1=CC=C(C=C1)C[C@H](C(=O)N[C@H](CC2=CC=CC=C2)C(=O)NC[C@@H]([C@H](C3=CC=C(C=C3)I)O)N)N	IC50 = 107100 nM	Poor binder
T80942	Matrix metalloproteinase 1	BW31OG	(Ethylamino)carbonylphosphonic acid	Investigative	11205873	C3H8NO4P	153.07	CCNC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BW31OG	(Ethylamino)carbonylphosphonic acid	Investigative	11205873	C3H8NO4P	153.07	CCNC(=O)P(=O)(O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BW4I1K	N-Hydroxycarbamoylmethyl-N-(1-methyl-butyl)-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide	Investigative	44327801	C31H38N4O5	546.7	CCCC(C)N(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BW53GL	(2S)-2-[[5-(Dimethylamino)naphthalen-1-yl]sulfonylamino]-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide	Investigative	90663077	C26H28N6O4S3	584.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C	Ki = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BW53GL	(2S)-2-[[5-(Dimethylamino)naphthalen-1-yl]sulfonylamino]-N-[(2S)-1-oxo-1-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)amino]propan-2-yl]-3-phenylpropanamide	Investigative	90663077	C26H28N6O4S3	584.7	C[C@@H](C(=O)NC1=NNC(=S)S1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C	Ki = 87000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BW5QT9	4-(1H-Pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-ylamine	Investigative	44426073	C10H9N5	199.21	C1=CNC(=C1)C2=NC=CC3=C2N=C(N3)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BW8Z6H	Dipotassium;2-[[2-[[(2S,3S)-2-[[ethoxy(oxido)phosphoryl]amino]-3-methylpentanoyl]amino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]-3-phenylpropanoate	Investigative	54586055	C33H40K2N3O8P	715.9	CC[C@H](C)[C@@H](C(=O)NC(CC1=CC=C(C=C1)OCC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)[O-])NP(=O)([O-])OCC.[K+].[K+]	Ki = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BW9K1L	4-Benzylsulfanyl-2-(4''-bromo-biphenyl-4-sulfonylamino)-butyric acid	Investigative	10506147	C23H22BrNO4S2	520.5	C1=CC=C(C=C1)CSCCC(C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Br	IC50 = 56000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BWF9E5	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-4-methylpentanamide	Investigative	56678867	C15H26N4O2	294.39	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)N)O)N)N	IC50 = 119300 nM	Poor binder
T80942	Matrix metalloproteinase 2	BWH48N	(2S)-2-Amino-4-methyl-N-[(2R)-2-amino-3-phenylpropyl]valeramide	Investigative	42645280	C15H25N3O	263.38	CC(C)C[C@@H](C(=O)NC[C@@H](CC1=CC=CC=C1)N)N	IC50 = 170200 nM	Poor binder
T80942	Matrix metalloproteinase 7	BWMA52	(2S)-2-Amino-5-(diaminomethylideneamino)-N-[4-[4-(thiiran-2-ylmethylsulfonyl)phenoxy]phenyl]pentanamide	Investigative	54669766	C21H27N5O4S2	477.6	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)N	Ki = 160000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BWP2L8	Chembl4210975	Investigative	145966162	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)OC	IC50 = 52100 nM	Poor binder
T80942	Matrix metalloproteinase 9	BWP2L8	Chembl4210975	Investigative	145966162	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)OC	IC50 = 54600 nM	Poor binder
T80942	Matrix metalloproteinase 12	BWR10G	Perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445221	C13H6F5NO3	319.18	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C(=C(C(=C2F)F)F)F)F	IC50 = 63000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BWR10G	Perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445221	C13H6F5NO3	319.18	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C(=C(C(=C2F)F)F)F)F	IC50 = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BWR10G	Perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445221	C13H6F5NO3	319.18	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C(=C(C(=C2F)F)F)F)F	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BWUH98	5-Pyridin-4-yl-1H-indole-2-carboxylic acid ethyl ester	Investigative	56850272	C16H14N2O2	266.29	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C3=CC=NC=C3	IC50 = 82000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BWY4L8	Chembl4203717	Investigative	145976282	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)OC	IC50 = 56100 nM	Poor binder
T80942	Matrix metalloproteinase 9	BWY4L8	Chembl4203717	Investigative	145976282	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)OC	IC50 = 57800 nM	Poor binder
T80942	Matrix metalloproteinase 1	BX05JE	Prop-2-enyl 2-[(E)-3-(4-chlorophenyl)prop-2-enoyl]oxy-3-(3,4-dimethoxyphenyl)propanoate	Investigative	71654194	C23H23ClO6	430.9	COC1=C(C=C(C=C1)CC(C(=O)OCC=C)OC(=O)/C=C/C2=CC=C(C=C2)Cl)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BX1NG5	Phenethylcarbamoylphosphonic Acid	Investigative	9794947	C9H12NO4P	229.17	C1=CC=C(C=C1)CCNC(=O)P(=O)(O)O	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BX1NG5	Phenethylcarbamoylphosphonic Acid	Investigative	9794947	C9H12NO4P	229.17	C1=CC=C(C=C1)CCNC(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BX1NG5	Phenethylcarbamoylphosphonic Acid	Investigative	9794947	C9H12NO4P	229.17	C1=CC=C(C=C1)CCNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BX1NG5	Phenethylcarbamoylphosphonic Acid	Investigative	9794947	C9H12NO4P	229.17	C1=CC=C(C=C1)CCNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BX28NQ	Chembl4164016	Investigative	145960035	C13H17N3O7S	359.36	CCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 87100 nM	Poor binder
T80942	Matrix metalloproteinase 12	BX28NQ	Chembl4164016	Investigative	145960035	C13H17N3O7S	359.36	CCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 109100 nM	Poor binder
T80942	Matrix metalloproteinase 9	BX34RO	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-6-ylbenzamide	Investigative	73055906	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CC5=C(C=C4)N=CC=C5)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BX34RO	N-(4-Amino-2-methylquinolin-6-yl)-3-quinolin-6-ylbenzamide	Investigative	73055906	C26H20N4O	404.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C4=CC5=C(C=C4)N=CC=C5)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BX35SB	Chembl4207416	Investigative	145978615	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BX35SB	Chembl4207416	Investigative	145978615	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BX35SB	Chembl4207416	Investigative	145978615	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BX46HB	4-(4-Benzyl-3,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	45485521	C17H13Br2N5	447.1	C1=CC=C(C=C1)CC2=C(NC(=C2Br)C3=NC=CC4=C3N=C(N4)N)Br	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BX6RI7	N-Hydroxycarbamoylmethyl-N-(1-methyl-butyl)-2-[3-naphthalen-2-yl-1-(1,2,3,4-tetrahydro-naphthalen-1-yl)-ureido]-acetamide	Investigative	44327914	C30H36N4O4	516.6	CCCC(C)N(CC(=O)NO)C(=O)CN(C1CCCC2=CC=CC=C12)C(=O)NC3=CC4=CC=CC=C4C=C3	IC50 = 120000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BX7B5M	4-(4,5-Dibromo-1H-pyrrol-2-yl)-1-methyl-1H-imidazo[4,5-c]pyridin-2-amine	Investigative	44426075	C11H9Br2N5	371.03	CN1C2=C(C(=NC=C2)C3=CC(=C(N3)Br)Br)N=C1N	IC50 = 56900 nM	Poor binder
T80942	Matrix metalloproteinase 12	BX7RZ0	3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445280	C16H17N5	279.34	C1=CC=C(C=C1)CCCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BX7RZ0	3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445280	C16H17N5	279.34	C1=CC=C(C=C1)CCCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BX7RZ0	3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445280	C16H17N5	279.34	C1=CC=C(C=C1)CCCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BX7RZ0	3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445280	C16H17N5	279.34	C1=CC=C(C=C1)CCCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BX8V6Y	N-[(2S,4S)-1-[4-[2-(2-Chloro-4-methylsulfonylphenyl)ethyl]piperidin-1-yl]sulfonyl-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide	Investigative	53320227	C25H34ClFN4O6S2	605.1	C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CC1)CCC2=C(C=C(C=C2)S(=O)(=O)C)Cl)N(C=O)O)C3=NC=C(C=N3)F	IC50 ~ 70000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BX95AE	2-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445224	C13H10BrNO3	308.13	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Br	IC50 = 57000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BX95AE	2-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445224	C13H10BrNO3	308.13	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Br	IC50 = 59000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BX9N5F	[3-(5-Thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetic acid ethyl ester	Investigative	44285516	C7H10N4O3S2	262.3	CCOC(=O)CNC(=O)NC1=NNC(=S)S1	Ki = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BX9QY5	4-(1-Methyl-4,5-dibromo-1H-pyrrole-2-yl)-1H-imidazo[4,5-c]pyridine-2-amine	Investigative	44426074	C11H9Br2N5	371.03	CN1C(=CC(=C1Br)Br)C2=NC=CC3=C2N=C(N3)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BXC13G	Secoisolariciresinol	Investigative	65373	C20H26O6	362.4	COC1=C(C=CC(=C1)C[C@@H](CO)[C@@H](CC2=CC(=C(C=C2)O)OC)CO)O	IC50 = 50120 nM	Poor binder
T80942	Matrix metalloproteinase 1	BXG18E	Dipotassium;2-[[(2S)-2-[[(2S,3S)-2-[[ethoxy(oxido)phosphoryl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetate	Investigative	73349984	C13H24K2N3O7P	443.52	CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)NCC(=O)[O-])NP(=O)([O-])OCC.[K+].[K+]	Ki = 130000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BXG5J0	Ubenimex	Investigative	72172	C16H24N2O4	308.37	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BXI61R	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036779	C17H10N4O3S2	382.4	C1=CC=C(C(=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)[N+](=O)[O-]	IC50 = 64000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BXIN13	(4S)-5-Amino-4-[[(2S)-4-carboxy-2-[3-(4-thiophen-2-ylphenyl)propanoylamino]butanoyl]amino]-5-oxopentanoic acid	Investigative	50991424	C23H27N3O7S	489.5	C1=CSC(=C1)C2=CC=C(C=C2)CCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BXO50L	(S,E)-5-(2-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582646	C22H23ClN2O6	446.9	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=CC=C2Cl)OC	IC50 = 64300 nM	Poor binder
T80942	Matrix metalloproteinase 2	BXS80V	(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	56672275	C24H35N5O3	441.6	CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)N)O)N)N	IC50 = 133800 nM	Poor binder
T80942	Matrix metalloproteinase 1	BXS9P4	4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445226	C13H10BrNO3	308.13	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Br	IC50 = 81000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BXS9P4	4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445226	C13H10BrNO3	308.13	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Br	IC50 = 105000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BXS9P4	4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445226	C13H10BrNO3	308.13	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Br	IC50 = 107000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BXS9P4	4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445226	C13H10BrNO3	308.13	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Br	IC50 = 114000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 = 71000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BXUI62	Benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate	Investigative	72714323	C26H27Br2N3O7S	685.4	C1=CC=C(C=C1)COC(=O)NCCC[C@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)OCC3=CC(=CC(=C3)Br)Br	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BXUI62	Benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate	Investigative	72714323	C26H27Br2N3O7S	685.4	C1=CC=C(C=C1)COC(=O)NCCC[C@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)OCC3=CC(=CC(=C3)Br)Br	IC50 = 370000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BXW5Y2	Pentan-3-ylcarbamoylphosphonic Acid	Investigative	11367571	C6H14NO4P	195.15	CCC(CC)NC(=O)P(=O)(O)O	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BXW5Y2	Pentan-3-ylcarbamoylphosphonic Acid	Investigative	11367571	C6H14NO4P	195.15	CCC(CC)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BXW5Y2	Pentan-3-ylcarbamoylphosphonic Acid	Investigative	11367571	C6H14NO4P	195.15	CCC(CC)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki = 91000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 = 91000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BY1JD8	N-(4-Amino-2-methylquinolin-6-yl)-4-phenoxybenzamide	Investigative	73054451	C23H19N3O2	369.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)OC4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BY1JD8	N-(4-Amino-2-methylquinolin-6-yl)-4-phenoxybenzamide	Investigative	73054451	C23H19N3O2	369.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)OC4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BY1W0D	5-(Benzothiazol-2-ylazamethylene)-1-(4-sulfophenyl)-2-pyrazoline-3-carboxylic acid	Investigative	6250177	C17H12N4O5S2	416.4	C\\1C(=NN(/C1=N\\C2=NC3=CC=CC=C3S2)C4=CC=C(C=C4)S(=O)(=O)O)C(=O)O	IC50 = 60100 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY1Z5G	(R)-5-(2,4-Difluorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582906	C21H22F2N2O7	452.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=C(C=C(C=C2)F)F	IC50 = 108700 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY23AO	N-[2-(4-Fluoro-phenyl)-ethyl]-2-[1-heptyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328259	C32H39FN4O5	578.7	CCCCCCCN(CC(=O)N(CCC1=CC=C(C=C1)F)CC(=O)NO)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 114000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY2AJ0	(S)-2-(2-(3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoic acid	Investigative	49863591	C19H24N4O6	404.4	C[C@@H](C(=O)O)NC(=O)CN1C(=O)CC[C@@H](C1=O)NC(=O)[C@H](CC2=CC=CC=C2)N	IC50 = 155000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY2DQ0	N-Tert-Butyl-N-hydroxycarbamoylmethyl-2-[3-(2-methylsulfanyl-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide	Investigative	44328254	C25H34N4O4S	486.6	CC(C)(C)N(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=CC=C2SC	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BY4F7G	4-[[4-Oxo-6-(3-piperidin-1-ylprop-1-ynyl)quinazolin-3-yl]methyl]benzoic acid	Investigative	22712801	C24H23N3O3	401.5	C1CCN(CC1)CC#CC2=CC3=C(C=C2)N=CN(C3=O)CC4=CC=C(C=C4)C(=O)O	IC50 = 75000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BY6OF9	2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-[4-(1H-[1,2,3]triazol-4-yl)-phenylsulfanyl]-cyclopentanecarboxylic acid	Investigative	44350116	C22H20N6O3S	448.5	C1C[C@@H]([C@H]([C@@H]1CN2C(=O)C3=CC=CC=C3N=N2)C(=O)O)SC4=CC=C(C=C4)C5=NNN=C5	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY8M6T	(2S)-N-(4-Fluorophenyl)-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide	Investigative	46232363	C26H23FN4O3	458.5	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)F	IC50 = 124320 nM	Poor binder
T80942	Matrix metalloproteinase 1	BY8QH0	Piperidin-1-ylcarbonylphosphonic acid	Investigative	44328155	C6H12NO4P	193.14	C1CCN(CC1)C(=O)P(=O)(O)O	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BY8QH0	Piperidin-1-ylcarbonylphosphonic acid	Investigative	44328155	C6H12NO4P	193.14	C1CCN(CC1)C(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BY8QH0	Piperidin-1-ylcarbonylphosphonic acid	Investigative	44328155	C6H12NO4P	193.14	C1CCN(CC1)C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BY97GQ	Ethyl 5-carbamoyl-1H-indole-2-carboxylate	Investigative	47162079	C12H12N2O3	232.23	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C(=O)N	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 13	BYMV71	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-chlorophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036767	C17H10ClN3OS2	371.9	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC(=CC=C4)Cl)/S3	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BYQI40	[Heptyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid	Investigative	44328168	C33H42N4O5	574.7	CCCCCCCN(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 150000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BYSM39	(+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic Acid	Investigative	44479702	C21H18O4S	366.4	CC(C1=CC=CC=C1S(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3)C(=O)O	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BYSM39	(+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic Acid	Investigative	44479702	C21H18O4S	366.4	CC(C1=CC=CC=C1S(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BYV2D6	(1R,2S,5R)-2-[4-(4-Chlorophenyl)phenyl]sulfanyl-5-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]cyclopentane-1-carboxylic acid	Investigative	44349787	C24H25ClN2O4S	473	CC1(C(=O)N(C(=O)N1)C[C@@H]2CC[C@@H]([C@H]2C(=O)O)SC3=CC=C(C=C3)C4=CC=C(C=C4)Cl)C	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZ15OK	(R)-Ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxylate	Investigative	10132758	C17H27N3O5	353.4	CCOC(=O)C1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BZ6T1Y	N-Hydroxy-N-[1-(4-methylidenecyclohexyl)-2-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylethyl]formamide	Investigative	10141443	C27H30N2O5S	494.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C4CCC(=C)CC4)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZ7P0A	2-[1-[2-(4-Fluoro-phenyl)-ethyl]-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-N-isopropyl-acetamide	Investigative	44327476	C28H31FN4O5	522.6	CC(C)N(CC(=O)NO)C(=O)CN(CCC1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BZ7R9X	(4R)-3-[4-(4-Fluorophenoxy)phenyl]sulfonyl-N-hydroxy-1,3-thiazolidine-4-carboxamide	Investigative	57394850	C16H15FN2O5S2	398.4	C1[C@H](N(CS1)S(=O)(=O)C2=CC=C(C=C2)OC3=CC=C(C=C3)F)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZ8IT5	2,4,5-Trifluorobenzyl 6-mercaptopicolinate	Investigative	44445258	C13H8F3NO2S	299.27	C1=CC(=S)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 90000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BZ8IT5	2,4,5-Trifluorobenzyl 6-mercaptopicolinate	Investigative	44445258	C13H8F3NO2S	299.27	C1=CC(=S)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 105000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BZ8IT5	2,4,5-Trifluorobenzyl 6-mercaptopicolinate	Investigative	44445258	C13H8F3NO2S	299.27	C1=CC(=S)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 106000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BZ8IT5	2,4,5-Trifluorobenzyl 6-mercaptopicolinate	Investigative	44445258	C13H8F3NO2S	299.27	C1=CC(=S)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 124000 nM	Poor binder
T80942	Matrix metalloproteinase 12	BZ97RT	3-Phenylpropyl 6-mercaptopicolinate	Investigative	44445246	C15H15NO2S	273.4	C1=CC=C(C=C1)CCCOC(=O)C2=CC=CC(=S)N2	IC50 = 85000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BZ97RT	3-Phenylpropyl 6-mercaptopicolinate	Investigative	44445246	C15H15NO2S	273.4	C1=CC=C(C=C1)CCCOC(=O)C2=CC=CC(=S)N2	IC50 = 95000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZ97RT	3-Phenylpropyl 6-mercaptopicolinate	Investigative	44445246	C15H15NO2S	273.4	C1=CC=C(C=C1)CCCOC(=O)C2=CC=CC(=S)N2	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BZ97RT	3-Phenylpropyl 6-mercaptopicolinate	Investigative	44445246	C15H15NO2S	273.4	C1=CC=C(C=C1)CCCOC(=O)C2=CC=CC(=S)N2	IC50 = 112000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BZ9DQ2	(4S)-5-Amino-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[3-[4-(4-phenylphenyl)phenyl]propanoylamino]propanoyl]amino]-5-oxopentanoic acid	Investigative	50991331	C32H33N5O5	567.6	C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)CCC(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CCC(=O)O)C(=O)N	Ki ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BZBI17	Thioacetic acid S-((4S,5S)-2-biphenyl-4-yl-5-vinyl-4,5-dihydro-oxazol-4-yl) ester	Investigative	44394758	C19H17NO2S	323.4	CC(=O)S[C@H]1[C@@H](OC(=N1)C2=CC=C(C=C2)C3=CC=CC=C3)C=C	Ki = 81000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZF41K	(2R)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-sulfanylpropanamide	Investigative	56658262	C12H18N4O4S	314.36	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CS)N)N)O)[N+](=O)[O-]	IC50 = 151600 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZK0R2	(2S)-2,6-Diamino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]hexanamide	Investigative	56672134	C15H27N5O2	309.41	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CCCCN)N)N)O)N	IC50 = 157400 nM	Poor binder
T80942	Matrix metalloproteinase 14	BZP8X7	[(4-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72204928	C7H10FNO6P2	285.1	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BZP8X7	[(4-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72204928	C7H10FNO6P2	285.1	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	BZP8X7	[(4-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72204928	C7H10FNO6P2	285.1	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)F	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	BZRO48	2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]acetic Acid	Investigative	10832925	C14H12BrNO4S	370.22	C1=CC(=CC=C1C2=CC=C(C=C2)Br)S(=O)(=O)NCC(=O)O	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	BZRO48	2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]acetic Acid	Investigative	10832925	C14H12BrNO4S	370.22	C1=CC(=CC=C1C2=CC=C(C=C2)Br)S(=O)(=O)NCC(=O)O	IC50 = 77000 nM	Poor binder
T80942	Matrix metalloproteinase 2	BZSF06	N-{2-[(4'-Cyano-1,1'-biphenyl-4-YL)oxy]ethyl}-N'-hydroxy-N-methylurea	Investigative	5326979	C17H17N3O3	311.33	CN(CCOC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)C(=O)NO	IC50 = 58000 nM	Poor binder
T80942	Matrix metalloproteinase 3	BZSF06	N-{2-[(4'-Cyano-1,1'-biphenyl-4-YL)oxy]ethyl}-N'-hydroxy-N-methylurea	Investigative	5326979	C17H17N3O3	311.33	CN(CCOC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)C(=O)NO	IC50 = 200000 nM	Poor binder
T80942	Matrix metalloproteinase 8	BZWU56	[(Naphthalen-1-ylamino)-phosphonomethyl]phosphonic acid	Investigative	19382975	C11H13NO6P2	317.17	C1=CC=C2C(=C1)C=CC=C2NC(P(=O)(O)O)P(=O)(O)O	IC50 = 61000 nM	Poor binder
T80942	Matrix metalloproteinase 14	BZWU56	[(Naphthalen-1-ylamino)-phosphonomethyl]phosphonic acid	Investigative	19382975	C11H13NO6P2	317.17	C1=CC=C2C(=C1)C=CC=C2NC(P(=O)(O)O)P(=O)(O)O	IC50 = 69000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D00TRF	2-(benzyloxyamino)-N-hydroxyacetamide	Investigative	44423683	C9H12N2O3	196.2	C1=CC=C(C=C1)CONCC(=O)NO	IC50 = 94000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D01BCK	N-hydroxy-1-naphthamide	Investigative	23382	C11H9NO2	187.19	C1=CC=C2C(=C1)C=CC=C2C(=O)NO	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D02ECA	PF-00356231	Investigative	448942	C25H20N2O3S	428.5	C1=CC=C(C=C1)[C@@H](CC(=O)O)NC(=O)C2=CC(=CS2)C3=CC=C(C=C3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D03QAN	N,N'-Bis(4-Amino-2-Methylquinolin-6-Yl)Urea	Investigative	71166	C21H20N6O	372.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC4=C(C=C(N=C4C=C3)C)N)N	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 14	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D04PAW	Methotrexate gamma-L-phenylalaninehydroxamic acid	Investigative	16216218	C29H32N10O6	616.6	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NO)C(=O)O	IC50 = 60000 nM	Poor binder
T80942	Matrix metalloproteinase 14	D04PAW	Methotrexate gamma-L-phenylalaninehydroxamic acid	Investigative	16216218	C29H32N10O6	616.6	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NO)C(=O)O	IC50 = 70000 nM	Poor binder
T80942	Matrix metalloproteinase 13	D04UBY	5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	45483018	C18H17NO3	295.3	C1=CC(=CC(=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O)C#N	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D04UBY	5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	45483018	C18H17NO3	295.3	C1=CC(=CC(=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O)C#N	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D05BMD	2-(4-chlorobenzyloxyamino)-N-hydroxyacetamide	Investigative	44423684	C9H11ClN2O3	230.65	C1=CC(=CC=C1CONCC(=O)NO)Cl	IC50 = 137000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D05THD	2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide	Investigative	44478925	C19H15NO4S	353.4	C1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 73000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D06HSC	Folate gamma-L-phenylalaninehydroxamic acid	Investigative	136117931	C28H29N9O7	603.6	.	IC50 = 65000 nM	Poor binder
T80942	Matrix metalloproteinase 14	D06HSC	Folate gamma-L-phenylalaninehydroxamic acid	Investigative	136117931	C28H29N9O7	603.6	.	IC50 = 80000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D06NDR	2-(4-chlorobenzyloxyamino)-N-hydroxyhexanamide	Investigative	44423687	C13H19ClN2O3	286.75	CCCCC(C(=O)NO)NOCC1=CC=C(C=C1)Cl	IC50 = 81800 nM	Poor binder
T80942	Matrix metalloproteinase 9	D06NDR	2-(4-chlorobenzyloxyamino)-N-hydroxyhexanamide	Investigative	44423687	C13H19ClN2O3	286.75	CCCCC(C(=O)NO)NOCC1=CC=C(C=C1)Cl	IC50 = 125000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D07LTB	5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione	Investigative	11673778	C16H12N2O4	296.28	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3C(=O)NC(=O)NC3=O	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D07MJD	[2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid	Investigative	44479701	C20H16O4S	352.4	C1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3CC(=O)O	IC50 = 74000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D07VXX	2-(benzyloxyamino)-N-hydroxy-3-methylpentanamide	Investigative	16721024	C13H20N2O3	252.31	CCC(C)C(C(=O)NO)NOCC1=CC=CC=C1	IC50 = 151000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D09GIL	5-Methyl-5-phenyl-pyrimidine-2,4,6-trione	Investigative	66160	C11H10N2O3	218.21	CC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2	IC50 = 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D09GIL	5-Methyl-5-phenyl-pyrimidine-2,4,6-trione	Investigative	66160	C11H10N2O3	218.21	CC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 8	D09USO	(biphenyl-3-ylamino)methylenediphosphonic acid	Investigative	5277466	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 = 52000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D09USO	(biphenyl-3-ylamino)methylenediphosphonic acid	Investigative	5277466	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D09USO	(biphenyl-3-ylamino)methylenediphosphonic acid	Investigative	5277466	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	D0A0FY	N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide	Investigative	44479457	C14H13NO5S	307.32	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2C(=O)NO	IC50 = 72000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D0A0FY	N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide	Investigative	44479457	C14H13NO5S	307.32	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2C(=O)NO	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0A0FY	N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide	Investigative	44479457	C14H13NO5S	307.32	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2C(=O)NO	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0B0UI	Methotrexate gamma-hydroxamic acid	Investigative	44428664	C20H23N9O5	469.5	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)NO)C(=O)O	IC50 = 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0B3UN	RXP470.1	Investigative	44580458	C35H35BrClN4O10P	818	C1=CC(=CC(=C1)Cl)C2=CC=C(C=C2)C3=NOC(=C3)C[C@H](CP(=O)(C4=CC=C(C=C4)Br)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N	Ki = 67000 nM	Poor binder
T80942	Matrix metalloproteinase 13	D0C1EQ	2-(2-(biphenyl-4-yl)ethylthio)acetic acid	Investigative	20348772	C16H16O2S	272.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCSCC(=O)O	IC50 = 95200 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0C1EQ	2-(2-(biphenyl-4-yl)ethylthio)acetic acid	Investigative	20348772	C16H16O2S	272.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCSCC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0D7GL	TROPOLONE	Investigative	10789	C7H6O2	122.12	C1=CC=C(C(=O)C=C1)O	IC50 = 146000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0F2HJ	2-Cinnamamido-N1-hydroxy-N4-pentylsuccinamide	Investigative	45257111	C18H25N3O4	347.4	CCCCCNC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 196500 nM	Poor binder
T80942	Matrix metalloproteinase 13	D0F4UT	2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid	Investigative	21496278	C16H16O3S	288.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCS(=O)CC(=O)O	IC50 = 95900 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0F4UT	2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid	Investigative	21496278	C16H16O3S	288.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCS(=O)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0FO2B	OXYQUINOLINE	Investigative	1923	C9H7NO	145.16	C1=CC2=C(C(=C1)O)N=CC=C2	IC50 = 130000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0G0OP	2-(4-chlorobenzyloxyamino)-N-hydroxypropanamide	Investigative	44423685	C10H13ClN2O3	244.67	CC(C(=O)NO)NOCC1=CC=C(C=C1)Cl	IC50 = 68000 nM	Poor binder
T80942	Matrix metalloproteinase 9	D0G0OP	2-(4-chlorobenzyloxyamino)-N-hydroxypropanamide	Investigative	44423685	C10H13ClN2O3	244.67	CC(C(=O)NO)NOCC1=CC=C(C=C1)Cl	IC50 = 141000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D0G3YZ	(+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	11391583	C17H18O3	270.32	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0G3YZ	(+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	11391583	C17H18O3	270.32	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0G3YZ	(+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	11391583	C17H18O3	270.32	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0K0YX	5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	44626352	C18H17NO3	295.3	C1=CC(=CC=C1CCC(CC(=O)O)O)C2=CC=C(C=C2)C#N	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0K4TI	5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione	Investigative	49292	C16H20N2O3	288.34	CCCCCCC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 13	D0LB0N	5-(biphenyl-4-yl)-3-oxopentanoic acid	Investigative	45483008	C17H16O3	268.31	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(=O)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0LB0N	5-(biphenyl-4-yl)-3-oxopentanoic acid	Investigative	45483008	C17H16O3	268.31	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(=O)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0LM2K	2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid	Investigative	45483015	C16H16O4S	304.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CCS(=O)(=O)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D0N8YA	Bb-3497	Investigative	159596	C16H31N3O4	329.43	CCCC[C@H](CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0N8YA	Bb-3497	Investigative	159596	C16H31N3O4	329.43	CCCC[C@H](CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0NP8A	UK-356618	Investigative	10370504	C34H43N3O4	557.7	CC1=C(C=CC(=C1)CCC[C@H](CC(=O)NO)C(=O)N[C@H](C(=O)N[C@H](C)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3	IC50 = 51000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0P2TS	UK-383367	Investigative	9818682	C15H24N4O4	324.38	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)N	IC50 ~ 60000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0Q4TA	ARP100	Investigative	10044321	C17H20N2O5S	364.4	CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0Q4TA	ARP100	Investigative	10044321	C17H20N2O5S	364.4	CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0Q9LC	5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione	Investigative	44385624	C22H24N2O3	364.4	CCCCCCC1(C(=O)NC(=O)NC1=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T80942	Matrix metalloproteinase 12	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 3	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 8	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T80942	Matrix metalloproteinase 13	D0TL3N	5-(biphenyl-4-yl)-3-methoxypentanoic acid	Investigative	45482998	C18H20O3	284.3	COC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 1	D0TL3N	5-(biphenyl-4-yl)-3-methoxypentanoic acid	Investigative	45482998	C18H20O3	284.3	COC(CCC1=CC=C(C=C1)C2=CC=CC=C2)CC(=O)O	IC50 ~ 98000 nM	Poor binder
T80942	Matrix metalloproteinase 2	D0UI1P	2-Cinnamamido-N4-hexyl-N1-hydroxysuccinamide	Investigative	46228278	C19H27N3O4	361.4	CCCCCCNC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 178600 nM	Poor binder
T80942	Matrix metalloproteinase 9	D0Y1XM	2-(benzyloxyamino)-N-hydroxyhexanamide	Investigative	44423686	C13H20N2O3	252.31	CCCCC(C(=O)NO)NOCC1=CC=CC=C1	IC50 = 81000 nM	Poor binder
T80942	Matrix metalloproteinase 7	D0Y7NV	5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione	Investigative	2220392	C18H16N2O3	308.3	CCC1(C(=O)NC(=O)NC1=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder