TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T81311	Endoplasmin	B4A2PH	4-[8-(2,4-Dimethoxyphenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136934959	C17H18N6O2S	370.4	COC1=CC(=C(C=C1)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N)OC	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	B6CTK0	4-[8-(3,5-Dimethylphenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136198649	C17H18N6S	338.4	CC1=CC(=CC(=C1)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N)C	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	B6X2AB	4-[6-Imino-8-[2-(trifluoromethoxy)phenyl]sulfanyl-7H-purin-3-yl]butanenitrile	Investigative	136934956	C16H13F3N6OS	394.4	C1=CC=C(C(=C1)OC(F)(F)F)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	BBD06T	Nc1ncn(CCCC#N)c2nc(Sc3cc(Cl)cc(Cl)c3)nc12	Investigative	136198648	C15H12Cl2N6S	379.3	C1=C(C=C(C=C1Cl)Cl)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N	IC50 = 100000 nM	Poor binder
T81311	Endoplasmin	BET27B	4-[8-[2-Chloro-5-(trifluoromethyl)phenyl]sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136198647	C16H12ClF3N6S	412.8	C1=CC(=C(C=C1C(F)(F)F)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N)Cl	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	BEV51C	4-[6-Imino-8-(2-methoxyphenyl)sulfanyl-7H-purin-3-yl]butanenitrile	Investigative	136934954	C16H16N6OS	340.4	COC1=CC=CC=C1SC2=NC3=C(N2)C(=N)N=CN3CCCC#N	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	BJ2BF8	4-[8-[2-(Hydroxymethyl)phenyl]sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136934955	C16H16N6OS	340.4	C1=CC=C(C(=C1)CO)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	BUR97Q	4-[8-(2,5-Dimethylphenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136934961	C17H18N6S	338.4	CC1=CC(=C(C=C1)C)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N	IC50 ~ 100000 nM	Poor binder
T81311	Endoplasmin	BXB9L4	4-[8-(2-Chlorophenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136934953	C15H13ClN6S	344.8	C1=CC=C(C(=C1)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N)Cl	IC50 = 100000 nM	Poor binder