TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T84397 Tubulin beta-1 chain B65PRQ 2-Methoxy-5-(3,4,5-trimethoxyanilino)phenol Investigative 10380369 C16H19NO5 305.32 COC1=C(C=C(C=C1)NC2=CC(=C(C(=C2)OC)OC)OC)O IC50 ~ 100000 nM Poor binder T84397 Tubulin beta-1 chain B8IT9L 2-Methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol Investigative 5386397 C18H20O5 316.3 COC1=C(C=C(C=C1)/C=C/C2=CC(=C(C(=C2)OC)OC)OC)O IC50 = 50000 nM Poor binder T84397 Tubulin beta-1 chain BB7CJ3 [2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenyl]-methanol Investigative 44367324 C18H22O6 334.4 COC1=C(C=C(C=C1)OCC2=CC(=C(C(=C2)OC)OC)OC)CO IC50 ~ 100000 nM Poor binder T84397 Tubulin beta-1 chain BL4SC9 (E)-3-(3,4,5-Trihydroxyphenyl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-one Investigative 44400896 C18H18O7 346.3 COC1=C(C(=C(C=C1)C(=O)/C=C/C2=CC(=C(C(=C2)O)O)O)OC)OC IC50 ~ 100000 nM Poor binder T84397 Tubulin beta-1 chain BQJ5L9 3',4',5'-Trimethoxy-3,4-dihydroxychalcone Investigative 14977376 C18H18O6 330.3 COC1=CC(=CC(=C1OC)OC)C(=O)/C=C/C2=CC(=C(C=C2)O)O IC50 ~ 100000 nM Poor binder T84397 Tubulin beta-1 chain BXYA92 3-[2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-phenoxy]-propane-1,2-diol Investigative 44367323 C20H26O8 394.4 COC1=C(C=C(C=C1)COC2=CC(=C(C(=C2)OC)OC)OC)OCC(CO)O IC50 ~ 100000 nM Poor binder