TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T84791	JUN activation domain binding protein	B1Q0VA	N-[2-(1,3-Thiazol-2-yl)ethyl]-8-[[7-[2-(1,3-thiazol-2-yl)ethylcarbamoyl]-1,5-naphthyridin-4-yl]disulfanyl]-1,5-naphthyridine-3-carboxamide	Investigative	137648465	C28H22N8O2S4	630.8	C1=CN=C2C=C(C=NC2=C1SSC3=C4C(=NC=C3)C=C(C=N4)C(=O)NCCC5=NC=CS5)C(=O)NCCC6=NC=CS6	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	B1ZBU8	N-Methyl-8-[[3-(methylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	Investigative	126599630	C22H18N4O2S2	434.5	CNC(=O)C1=CN=C2C(=C1)C=CC=C2SSC3=CC=CC4=CC(=CN=C43)C(=O)NC	IC50 = 68000 nM	Poor binder
T84791	JUN activation domain binding protein	B3M2RD	N-(2-Morpholin-4-ylethyl)-8-[[3-(2-morpholin-4-ylethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	Investigative	126599607	C32H36N6O4S2	632.8	C1COCCN1CCNC(=O)C2=CN=C3C(=C2)C=CC=C3SSC4=CC=CC5=CC(=CN=C54)C(=O)NCCN6CCOCC6	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	B4K1NP	2-Methylquinoline-8-thiol	Investigative	11298263	C10H9NS	175.25	CC1=NC2=C(C=CC=C2S)C=C1	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	B5XW6U	N-(Pyridin-3-ylmethyl)-8-[[3-(pyridin-3-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	Investigative	126599610	C32H24N6O2S2	588.7	C1=CC2=CC(=CN=C2C(=C1)SSC3=CC=CC4=CC(=CN=C43)C(=O)NCC5=CN=CC=C5)C(=O)NCC6=CN=CC=C6	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	B63UFS	N-[[4-(Trifluoromethyl)phenyl]methyl]-8-[[3-[[4-(trifluoromethyl)phenyl]methylcarbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	Investigative	126599615	C36H24F6N4O2S2	722.7	C1=CC2=CC(=CN=C2C(=C1)SSC3=CC=CC4=CC(=CN=C43)C(=O)NCC5=CC=C(C=C5)C(F)(F)F)C(=O)NCC6=CC=C(C=C6)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	B6ZTJ4	8-Methylsulfanyl-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamide	Investigative	126609831	C16H15N3OS2	329.4	CSC1=CC=CC2=CC(=CN=C21)C(=O)NCCC3=NC=CS3	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	BGC37O	8-Hydroxy-N-[2-(1,3-thiazol-2-yl)ethyl]quinoline-3-carboxamide	Investigative	137644943	C15H13N3O2S	299.3	C1=CC2=CC(=CN=C2C(=C1)O)C(=O)NCCC3=NC=CS3	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	BKLJ68	Methyl 2-[[8-[[3-[(2-methoxy-2-oxoethyl)carbamoyl]quinolin-8-yl]disulfanyl]quinoline-3-carbonyl]amino]acetate	Investigative	137644814	C26H22N4O6S2	550.6	COC(=O)CNC(=O)C1=CN=C2C(=C1)C=CC=C2SSC3=CC=CC4=CC(=CN=C43)C(=O)NCC(=O)OC	IC50 ~ 100000 nM	Poor binder
T84791	JUN activation domain binding protein	BY8GF2	N-(Pyridin-2-ylmethyl)-8-[[3-(pyridin-2-ylmethylcarbamoyl)quinolin-8-yl]disulfanyl]quinoline-3-carboxamide	Investigative	126599616	C32H24N6O2S2	588.7	C1=CC=NC(=C1)CNC(=O)C2=CN=C3C(=C2)C=CC=C3SSC4=CC=CC5=CC(=CN=C54)C(=O)NCC6=CC=CC=N6	IC50 ~ 50000 nM	Poor binder