TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T85221 Glucose-6-phosphatase B3O0JS [4-(Dibenzyl-hydrazonomethyl)-phenyl]-dimethyl-amine Investigative 9777510 C23H25N3 343.5 CN(C)C1=CC=C(C=C1)/C=N/N(CC2=CC=CC=C2)CC3=CC=CC=C3 IC50 = 100000 nM Poor binder T85221 Glucose-6-phosphatase B84FIC 2-Amino-4-(2,4-dimethoxyphenyl)-5-(4-fluorophenyl)-6-methylsulfanylbenzene-1,3-dicarbonitrile Investigative 44591656 C23H18FN3O2S 419.5 COC1=CC(=C(C=C1)C2=C(C(=C(C(=C2C3=CC=C(C=C3)F)SC)C#N)N)C#N)OC IC50 = 79000 nM Poor binder T85221 Glucose-6-phosphatase BA1O7J N,N-Dibenzyl-N''-[1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazine Investigative 9729606 C19H17N3O3 335.4 C1=CC=C(C=C1)CN(CC2=CC=CC=C2)/N=C/C3=CC=C(O3)[N+](=O)[O-] IC50 ~ 100000 nM Poor binder T85221 Glucose-6-phosphatase BM8ZI4 N,N-Dibenzyl-N''-[1-(3,5-dichloro-phenyl)-meth-(E)-ylidene]-hydrazine Investigative 9864110 C21H18Cl2N2 369.3 C1=CC=C(C=C1)CN(CC2=CC=CC=C2)/N=C/C3=CC(=CC(=C3)Cl)Cl IC50 ~ 100000 nM Poor binder T85221 Glucose-6-phosphatase BQMW54 N,N-Dibenzyl-N''-[2-phenyl-eth-(E)-ylidene]-hydrazine Investigative 44308842 C22H22N2 314.4 C1=CC=C(C=C1)C/C=N/N(CC2=CC=CC=C2)CC3=CC=CC=C3 IC50 ~ 100000 nM Poor binder T85221 Glucose-6-phosphatase BUR2L9 N,N-Dibenzyl-N''-[1-(2-methoxy-phenyl)-meth-(E)-ylidene]-hydrazine Investigative 9690863 C22H22N2O 330.4 COC1=CC=CC=C1/C=N/N(CC2=CC=CC=C2)CC3=CC=CC=C3 IC50 ~ 100000 nM Poor binder T85221 Glucose-6-phosphatase BX8JA1 N-Benzyl-N-[(E)-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)amino]-1-phenylmethanamine Investigative 44308851 C25H26N2O 370.5 COC1=CC2=C(C=C1)/C(=N/N(CC3=CC=CC=C3)CC4=CC=CC=C4)/CCC2 IC50 ~ 50000 nM Poor binder