TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T85223	Deoxyribonuclease I	B0UYF1	1-[(4-Chlorophenyl)methyl]-3-[(3,4-dihydroxyphenyl)methyl]imidazolidin-2-one	Investigative	122189975	C17H17ClN2O3	332.8	C1CN(C(=O)N1CC2=CC=C(C=C2)Cl)CC3=CC(=C(C=C3)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B0X4RF	5-(3-Chloro-4-fluorophenyl)-3-hydroxy-1H-pyridin-2-one	Investigative	122189979	C11H7ClFNO2	239.63	C1=CC(=C(C=C1C2=CNC(=O)C(=C2)O)Cl)F	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B10LCP	N-[(2,4-Dichlorophenyl)methyl]-2-(3,4-dihydroxyphenyl)acetamide	Investigative	122189973	C15H13Cl2NO3	326.2	C1=CC(=C(C=C1CC(=O)NCC2=C(C=C(C=C2)Cl)Cl)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B1ZR6L	N-[4-(5-Hydroxy-6-oxo-1H-pyridin-3-yl)phenyl]acetamide	Investigative	122189980	C13H12N2O3	244.25	CC(=O)NC1=CC=C(C=C1)C2=CNC(=O)C(=C2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B21LGW	2-Anilino-N-[2-(3,4-dihydroxyphenyl)ethyl]acetamide	Investigative	10016842	C16H18N2O3	286.33	C1=CC=C(C=C1)NCC(=O)NCCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B23YAZ	N'-[(E)-(3,4-Dihydroxyphenyl)methylidene]-2-(phenylamino)acetohydrazide (non-preferred name)	Investigative	135765525	C15H15N3O3	285.3	C1=CC=C(C=C1)NCC(=O)N/N=C/C2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B23ZBE	1-(2,4-Dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]methanesulfonamide	Investigative	122189972	C14H13Cl2NO4S	362.2	C1=CC(=C(C=C1CNS(=O)(=O)CC2=C(C=C(C=C2)Cl)Cl)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B29UBK	5-Hydroxy-N-(2-morpholin-4-ylethyl)-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094885	C15H18N4O4S	350.4	C1COCCN1CCNC(=O)C2=C(C(=O)NC(=N2)C3=CC=CS3)O	IC50 = 58900 nM	Poor binder
T85223	Deoxyribonuclease I	B2S1FT	2-(4-Acetylpiperazin-1-yl)-N-[(3,4-dihydroxyphenyl)methyl]acetamide	Investigative	122189966	C15H21N3O4	307.34	CC(=O)N1CCN(CC1)CC(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B2VLF7	N-Butan-2-yl-5-hydroxy-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094880	C13H15N3O3S	293.34	CCC(C)NC(=O)C1=C(C(=O)NC(=N1)C2=CC=CS2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B4A1ZV	3-Hydroxy-5-(1-methylindazol-6-yl)-1H-pyridin-2-one	Investigative	122189981	C13H11N3O2	241.24	CN1C2=C(C=CC(=C2)C3=CNC(=O)C(=C3)O)C=N1	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B4KP5C	N-(3-Hydroxy-2,4-dioxo-1H-quinazolin-8-yl)acetamide	Investigative	122190088	C10H9N3O4	235.2	CC(=O)NC1=CC=CC2=C1NC(=O)N(C2=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B4OWA7	5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid methyl ester	Investigative	135446971	C10H8N2O4S	252.25	COC(=O)C1=C(C(=O)NC(=N1)C2=CC=CS2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B4QF1Z	3-Hydroxy-6-phenyl-1H-pyrimidine-2,4-dione	Investigative	122190090	C10H8N2O3	204.18	C1=CC=C(C=C1)C2=CC(=O)N(C(=O)N2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B5PZ8U	N-[(3,4-Dihydroxyphenyl)methyl]-1-[(4-fluorophenyl)methyl]piperidine-4-carboxamide	Investigative	122189967	C20H23FN2O3	358.4	C1CN(CCC1C(=O)NCC2=CC(=C(C=C2)O)O)CC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B5QR4U	N-[(2-Chloro-3,4-dihydroxyphenyl)methyl]-2-(2,4-dichlorophenyl)acetamide	Investigative	122189970	C15H12Cl3NO3	360.6	C1=CC(=C(C=C1Cl)Cl)CC(=O)NCC2=C(C(=C(C=C2)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B6W2QX	3-Hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dione	Investigative	315023	C6H4N2O3S	184.17	C1=CSC2=C1C(=O)N(C(=O)N2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B7D5HR	1-(4-Chlorophenyl)-3-[(3,4-dihydroxyphenyl)methyl]urea	Investigative	122189974	C14H13ClN2O3	292.72	C1=CC(=CC=C1NC(=O)NCC2=CC(=C(C=C2)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B87JCI	2-(2,4-Dichlorophenyl)-N-[(2-fluoro-4,5-dihydroxyphenyl)methyl]acetamide	Investigative	122189971	C15H12Cl2FNO3	344.2	C1=CC(=C(C=C1Cl)Cl)CC(=O)NCC2=CC(=C(C=C2F)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B8JD2A	N-(3-Hydroxy-2,4-dioxo-1H-quinazolin-6-yl)acetamide	Investigative	122190089	C10H9N3O4	235.2	CC(=O)NC1=CC2=C(C=C1)NC(=O)N(C2=O)O	IC50 = 87000 nM	Poor binder
T85223	Deoxyribonuclease I	B8WI6J	5-Hydroxy-N-methyl-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094876	C10H9N3O3S	251.26	CNC(=O)C1=C(C(=O)NC(=N1)C2=CC=CS2)O	IC50 = 67600 nM	Poor binder
T85223	Deoxyribonuclease I	B9JH4K	5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid	Investigative	135433415	C9H6N2O4S	238.22	C1=CSC(=C1)C2=NC(=C(C(=O)N2)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	B9RVN8	4-[3-[(4-Chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]benzene-1,2-diol	Investigative	136094868	C15H11ClN2O3	302.71	C1=CC(=CC=C1CC2=NOC(=N2)C3=CC(=C(C=C3)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BAV0M7	N-[(3,4-Dihydroxyphenyl)methyl]benzamide	Investigative	12240669	C14H13NO3	243.26	C1=CC=C(C=C1)C(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BB8H1R	5,6-Dihydroxy-2-phenylpyrimidine-4-carboxylic acid	Investigative	135406878	C11H8N2O4	232.19	C1=CC=C(C=C1)C2=NC(=C(C(=O)N2)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BD4Q8N	5-Hydroxy-N-(2-hydroxyethyl)-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094878	C11H11N3O4S	281.29	C1=CSC(=C1)C2=NC(=C(C(=O)N2)O)C(=O)NCCO	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BDJ8X9	2-(2,4-Dichlorophenyl)-1-(6,7-dihydroxy-3,4-dihydro-1H-isoquinolin-2-yl)ethanone	Investigative	122189968	C17H15Cl2NO3	352.2	C1CN(CC2=CC(=C(C=C21)O)O)C(=O)CC3=C(C=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BE2NG6	N-[(3,4-Dihydroxyphenyl)methyl]-3-phenylpropanamide	Investigative	122189952	C16H17NO3	271.31	C1=CC=C(C=C1)CCC(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BFJZ41	N-[(3,4-Dihydroxyphenyl)methyl]-2-phenylacetamide	Investigative	122189954	C15H15NO3	257.279	C1=CC=C(C=C1)CC(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BH5NJ3	2-(4-Chlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamide	Investigative	122189956	C15H14ClNO3	291.73	C1=CC(=CC=C1CC(=O)NCC2=CC(=C(C=C2)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BI8VF5	N-(4-Fluorobenzyl)-5,6-dihydroxy-2-thien-2-ylpyrimidine-4-carboxamide	Investigative	135520683	C16H12FN3O3S	345.3	C1=CSC(=C1)C2=NC(=C(C(=O)N2)O)C(=O)NCC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BK2CI1	Methyl 5,6-dihydroxy-2-phenylpyrimidine-4-carboxylate	Investigative	135483599	C12H10N2O4	246.22	COC(=O)C1=C(C(=O)NC(=N1)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BK5RS0	2-Anilino-N-[(3,4-dihydroxyphenyl)methyl]acetamide	Investigative	122189950	C15H16N2O3	272.3	C1=CC=C(C=C1)NCC(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BM84JO	5-(4-Fluorophenyl)-3-hydroxy-1H-pyridin-2-one	Investigative	72204354	C11H8FNO2	205.18	C1=CC(=CC=C1C2=CNC(=O)C(=C2)O)F	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BP3Y5J	1-Benzyl-3-hydroxythieno[2,3-d]pyrimidine-2,4(1H,3H)-dione	Investigative	44392260	C13H10N2O3S	274.3	C1=CC=C(C=C1)CN2C3=C(C=CS3)C(=O)N(C2=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BPX1M7	2-Anilino-N-(3,4-dihydroxyphenyl)acetamide	Investigative	122189951	C14H14N2O3	258.269	C1=CC=C(C=C1)NCC(=O)NC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BPYL64	N-(3-Hydroxy-2,4-dioxo-1H-quinazolin-7-yl)acetamide	Investigative	332819	C10H9N3O4	235.2	CC(=O)NC1=CC2=C(C=C1)C(=O)N(C(=O)N2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BQAV74	5-Hydroxy-1-methyl-6-oxo-2-(2-thienyl)pyrimidine-4-carboxylic acid	Investigative	54727893	C10H8N2O4S	252.25	CN1C(=NC(=C(C1=O)O)C(=O)O)C2=CC=CS2	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BQOY73	3-Hydroxy-1-methylquinazoline-2,4(1H,3H)-dione	Investigative	303856	C9H8N2O3	192.17	CN1C2=CC=CC=C2C(=O)N(C1=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BQR52K	3-Hydroxy-7-(4-methylphenyl)furo[3,2-d]pyrimidine-2,4(1H,3H)-dione	Investigative	44392232	C13H10N2O4	258.23	CC1=CC=C(C=C1)C2=COC3=C2NC(=O)N(C3=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BR6LW5	3-Hydroxy-5-(3-pyrazol-1-ylphenyl)-1H-pyridin-2-one	Investigative	122189978	C14H11N3O2	253.26	C1=CC(=CC(=C1)N2C=CC=N2)C3=CNC(=O)C(=C3)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BRQ25O	5-Hydroxy-6-oxo-N-pyridin-3-yl-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094884	C14H10N4O3S	314.32	C1=CC(=CN=C1)NC(=O)C2=C(C(=O)NC(=N2)C3=CC=CS3)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BT2O1V	3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dione	Investigative	11507180	C12H8N2O3S	260.269	C1=CC=C(C=C1)C2=CSC3=C2NC(=O)N(C3=O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BT68JB	N-[(3,4-Dihydroxyphenyl)methyl]-2-phenoxyacetamide	Investigative	122189953	C15H15NO4	273.28	C1=CC=C(C=C1)OCC(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BV1SR3	2-(2,4-Dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]-N-methylacetamide	Investigative	122189969	C16H15Cl2NO3	340.2	CN(CC1=CC(=C(C=C1)O)O)C(=O)CC2=C(C=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BV39AW	2-(2-Chlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamide	Investigative	122189957	C15H14ClNO3	291.73	C1=CC=C(C(=C1)CC(=O)NCC2=CC(=C(C=C2)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BV6I8T	5-Hydroxy-6-oxo-N-propyl-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094877	C12H13N3O3S	279.32	CCCNC(=O)C1=C(C(=O)NC(=N1)C2=CC=CS2)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BV96LM	2-(2,4-Dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamide	Investigative	122189958	C15H13Cl2NO3	326.2	C1=CC(=C(C=C1CNC(=O)CC2=C(C=C(C=C2)Cl)Cl)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BW20XS	N-[(3,4-Dihydroxyphenyl)methyl]cyclopentanecarboxamide	Investigative	122189961	C13H17NO3	235.28	C1CCC(C1)C(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BW32XZ	N'-[(E)-(2,5-Dibromo-3,4-dihydroxyphenyl)methylidene]-2-[(3-methylphenyl)amino]acetohydrazide (non-preferred name)	Investigative	135419769	C16H15Br2N3O3	457.12	CC1=CC(=CC=C1)NCC(=O)N/N=C/C2=CC(=C(C(=C2Br)O)O)Br	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BX9E8L	N-[(3,4-Dihydroxyphenyl)methyl]-2-(4-morpholin-4-ylphenyl)acetamide	Investigative	122189965	C19H22N2O4	342.4	C1COCCN1C2=CC=C(C=C2)CC(=O)NCC3=CC(=C(C=C3)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BYF9G5	4-[[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]benzene-1,2-diol	Investigative	122189976	C15H11ClN2O3	302.71	C1=CC(=CC=C1C2=NOC(=N2)CC3=CC(=C(C=C3)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BZ96RG	N-(2-Acetamidoethyl)-5-hydroxy-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamide	Investigative	136094882	C13H14N4O4S	322.34	CC(=O)NCCNC(=O)C1=C(C(=O)NC(=N1)C2=CC=CS2)O	IC50 = 62600 nM	Poor binder
T85223	Deoxyribonuclease I	BZI27T	5,6-Dihydroxy-2-(2-thienyl)pyrimidine-4-carboxamide	Investigative	135446332	C9H7N3O3S	237.24	C1=CSC(=C1)C2=NC(=C(C(=O)N2)O)C(=O)N	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	BZJ9L6	2-Cyclohexyl-N-[(3,4-dihydroxyphenyl)methyl]acetamide	Investigative	122189962	C15H21NO3	263.33	C1CCC(CC1)CC(=O)NCC2=CC(=C(C=C2)O)O	IC50 ~ 100000 nM	Poor binder
T85223	Deoxyribonuclease I	D0NS0E	3-hydroxyquinazoline-2,4(1H,3H)-dione	Investigative	220188	C8H6N2O3	178.14	C1=CC=C2C(=C1)C(=O)N(C(=O)N2)O	IC50 ~ 100000 nM	Poor binder