TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T86264 Solute carrier family 40 member 1 B2D5YX N-(2-Chloroquinolin-8-yl)benzenesulfonamide Investigative 86669756 C15H11ClN2O2S 318.8 C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC3=C2N=C(C=C3)Cl IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B2E5KM 2-Amino-4-methyl-N-(3-methylquinolin-8-yl)-benzenesulfonamide Investigative 68182972 C17H17N3O2S 327.4 CC1=CC(=C(C=C1)S(=O)(=O)NC2=CC=CC3=C2N=CC(=C3)C)N IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B2NZ1Y N-(2-Methylquinolin-8-yl)benzenesulfonamide Investigative 2848041 C16H14N2O2S 298.4 CC1=NC2=C(C=CC=C2NS(=O)(=O)C3=CC=CC=C3)C=C1 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B3NWV7 2,4-Dichloro-N-(5-chloroquinolin-8-yl)benzenesulfonamide Investigative 68183486 C15H9Cl3N2O2S 387.7 C1=CC2=C(C=CC(=C2N=C1)NS(=O)(=O)C3=C(C=C(C=C3)Cl)Cl)Cl IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B43EOH 2-Amino-N-(5-chloroquinolin-8-yl)-4-(trifluoromethyl)benzenesulfonamide Investigative 68183012 C16H11ClF3N3O2S 401.8 C1=CC2=C(C=CC(=C2N=C1)NS(=O)(=O)C3=C(C=C(C=C3)C(F)(F)F)N)Cl IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B6ERT4 2-Amino-4-methoxy-N-(2-methylquinolin-8-yl)benzenesulfonamide Investigative 16759948 C17H17N3O3S 343.4 CC1=NC2=C(C=CC=C2NS(=O)(=O)C3=C(C=C(C=C3)OC)N)C=C1 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B7NXH8 N-(7-Ethylquinolin-8-yl)benzenesulfonamide Investigative 68183379 C17H16N2O2S 312.4 CCC1=C(C2=C(C=CC=N2)C=C1)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B7YWD2 11-Methoxy-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide Investigative 60164093 C16H12N2O3S 312.3 COC1=C2C3=CC=CC=C3S(=O)(=O)NC2=C4C(=C1)C=CC=N4 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B80HFZ N-(5-Chloro-6-methylquinolin-8-yl)benzenesulfonamide Investigative 60164004 C16H13ClN2O2S 332.8 CC1=CC(=C2C(=C1Cl)C=CC=N2)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B8D3VY 1-Methoxy-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide Investigative 68183376 C16H12N2O3S 312.3 COC1=C2C=CC3=C(C2=NC=C1)NS(=O)(=O)C4=CC=CC=C34 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B8F6BP Methyl 2-(quinolin-8-ylsulfamoyl)benzoate Investigative 8823684 C17H14N2O4S 342.4 COC(=O)C1=CC=CC=C1S(=O)(=O)NC2=CC=CC3=C2N=CC=C3 IC50 = 58100 nM Poor binder T86264 Solute carrier family 40 member 1 B9EB8F N-(5,6-Dimethylquinolin-8-yl)benzenesulfonamide Investigative 68183094 C17H16N2O2S 312.4 CC1=CC(=C2C(=C1C)C=CC=N2)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 B9HQO4 N-(4-Methoxyquinolin-8-yl)benzenesulfonamide Investigative 68183281 C16H14N2O3S 314.4 COC1=C2C=CC=C(C2=NC=C1)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BA3GB9 Methyl 8-(benzenesulfonamido)quinoline-4-carboxylate Investigative 68183202 C17H14N2O4S 342.4 COC(=O)C1=C2C=CC=C(C2=NC=C1)NS(=O)(=O)C3=CC=CC=C3 IC50 = 50000 nM Poor binder T86264 Solute carrier family 40 member 1 BA43VT 5-Methyl-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide Investigative 68183288 C16H12N2O2S 296.3 CN1C2=C(C=CC3=C2N=CC=C3)C4=CC=CC=C4S1(=O)=O IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BC2BH8 N-(2,6-Difluorophenyl)[(6-methoxyquinolin-8-yl)amino]sulfonamide Investigative 68183303 C16H13F2N3O3S 365.4 COC1=CC(=C2C(=C1)C=CC=N2)NS(=O)(=O)NC3=C(C=CC=C3F)F IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BF72LW 2,4-Dichloro-N-(3-methylquinolin-8-yl)benzenesulfonamide Investigative 60164002 C16H12Cl2N2O2S 367.2 CC1=CC2=C(C(=CC=C2)NS(=O)(=O)C3=C(C=C(C=C3)Cl)Cl)N=C1 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BHA49X N-(6-Chloroquinolin-8-yl)benzenesulfonamide Investigative 60163755 C15H11ClN2O2S 318.8 C1=CC=C(C=C1)S(=O)(=O)NC2=C3C(=CC(=C2)Cl)C=CC=N3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BHF8O7 2,4-Dichloro-N-(6-methoxyquinolin-8-yl)benzenesulfonamide Investigative 68183309 C16H12Cl2N2O3S 383.2 COC1=CC(=C2C(=C1)C=CC=N2)NS(=O)(=O)C3=C(C=C(C=C3)Cl)Cl IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BI54CW N-(7-Methylquinolin-8-yl)benzenesulfonamide Investigative 60163754 C16H14N2O2S 298.4 CC1=C(C2=C(C=CC=N2)C=C1)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BJ36MG N-(5,7-Dichloroquinolin-8-yl)-4-methylbenzenesulfonamide Investigative 1070163 C16H12Cl2N2O2S 367.2 CC1=CC=C(C=C1)S(=O)(=O)NC2=C(C=C(C3=C2N=CC=C3)Cl)Cl IC50 = 79000 nM Poor binder T86264 Solute carrier family 40 member 1 BJE40I N-[2-(Quinolin-8-ylsulfamoyl)-5-(trifluoromethyl)phenyl]acetamide Investigative 68183415 C18H14F3N3O3S 409.4 CC(=O)NC1=C(C=CC(=C1)C(F)(F)F)S(=O)(=O)NC2=CC=CC3=C2N=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BKG6Z3 OC1=CC=C2C=CC=NC2=C1NS(=O)(=O)C1=CC=CC=C1 Investigative 136464865 C15H12N2O3S 300.3 C1=CC=C(C=C1)S(=O)(=O)NC2=C(C=CC3=C2N=CC=C3)O IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BL4D6N N-(5,7-Dichloroquinolin-8-yl)-2,4,6-trimethylbenzenesulfonamide Investigative 1380889 C18H16Cl2N2O2S 395.3 CC1=CC(=C(C(=C1)C)S(=O)(=O)NC2=C(C=C(C3=C2N=CC=C3)Cl)Cl)C IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BMCR92 2-Methyl-N-(8-quinolinyl)benzenesulfonamide Investigative 49766557 C16H14N2O2S 298.4 CC1=CC=CC=C1S(=O)(=O)NC2=CC=CC3=C2N=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BN3PY9 2-Amino-4-methoxy-N-quinolin-8-ylbenzenesulfonamide Investigative 16759517 C16H15N3O3S 329.4 COC1=CC(=C(C=C1)S(=O)(=O)NC2=CC=CC3=C2N=CC=C3)N IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BN4G6R 3-Methyl-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide Investigative 16759520 C16H12N2O2S 296.3 CC1=NC2=C(C=C1)C=CC3=C2NS(=O)(=O)C4=CC=CC=C34 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BNMQ71 N-(5-Bromoquinolin-8-yl)benzenesulfonamide Investigative 5009224 C15H11BrN2O2S 363.2 C1=CC=C(C=C1)S(=O)(=O)NC2=C3C(=C(C=C2)Br)C=CC=N3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BO1GT7 2-Methoxy-N-quinolin-8-ylbenzenesulfonamide Investigative 51238103 C16H14N2O3S 314.4 COC1=CC=CC=C1S(=O)(=O)NC2=CC=CC3=C2N=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BO3QL0 4-Methoxy-N-quinolin-8-ylbenzenesulfonamide Investigative 4215345 C16H14N2O3S 314.4 COC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC3=C2N=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BO78AC 5-Chloro-N-[(3-chloro-2-methylphenyl)sulfamoyl]quinolin-8-amine Investigative 68183263 C16H13Cl2N3O2S 382.3 CC1=C(C=CC=C1Cl)NS(=O)(=O)NC2=C3C(=C(C=C2)Cl)C=CC=N3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BO9BR1 N-(6-Ethoxyquinolin-8-yl)benzenesulfonamide Investigative 68183443 C17H16N2O3S 328.4 CCOC1=CC(=C2C(=C1)C=CC=N2)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BPRN73 2-Nitro-N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamide Investigative 16759914 C16H10F3N3O4S 397.3 C1=CC2=C(C(=C1)NS(=O)(=O)C3=C(C=C(C=C3)C(F)(F)F)[N+](=O)[O-])N=CC=C2 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BQ94PU N-(7-Methoxyquinolin-8-yl)benzenesulfonamide Investigative 60164090 C16H14N2O3S 314.4 COC1=C(C2=C(C=CC=N2)C=C1)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BS62EL 2,6-Dichloro-N-quinolin-8-ylbenzenesulfonamide Investigative 28046588 C15H10Cl2N2O2S 353.2 C1=CC2=C(C(=C1)NS(=O)(=O)C3=C(C=CC=C3Cl)Cl)N=CC=C2 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BURQ82 2-Amino-N-(2-methylquinolin-8-yl)benzenesulfonamide Investigative 16759519 C16H15N3O2S 313.4 CC1=NC2=C(C=CC=C2NS(=O)(=O)C3=CC=CC=C3N)C=C1 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BW60UM 2-Chloro-6-methyl-N-quinolin-8-ylbenzenesulfonamide Investigative 68183207 C16H13ClN2O2S 332.8 CC1=C(C(=CC=C1)Cl)S(=O)(=O)NC2=CC=CC3=C2N=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BX2QE3 N-(7-Isopropyl-quinolin-8-yl)-benzenesulfonamide Investigative 68183244 C18H18N2O2S 326.4 CC(C)C1=C(C2=C(C=CC=N2)C=C1)NS(=O)(=O)C3=CC=CC=C3 IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BYBI53 N-(7-Chloroquinolin-8-yl)benzenesulfonamide Investigative 60164005 C15H11ClN2O2S 318.8 C1=CC=C(C=C1)S(=O)(=O)NC2=C(C=CC3=C2N=CC=C3)Cl IC50 = 100000 nM Poor binder T86264 Solute carrier family 40 member 1 BZ6L4B N-[(3-Chloro-2-methylphenyl)sulfamoyl]-6-methoxyquinolin-8-amine Investigative 68183460 C17H16ClN3O3S 377.8 CC1=C(C=CC=C1Cl)NS(=O)(=O)NC2=C3C(=CC(=C2)OC)C=CC=N3 IC50 = 100000 nM Poor binder