TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86552	Tumor necrosis factor receptor type I	B35TFL	1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propene-1-one	Investigative	6091793	C24H30O3	366.5	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)/C=C/C2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T86552	Tumor necrosis factor receptor type I	B4AFG7	3-(5-Bromo-2,4-dimethoxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propan-1-one	Investigative	44284902	C20H23BrO6	439.3	COC1=CC(=CC(=C1OC)OC)C(=O)CCC2=CC(=C(C=C2OC)OC)Br	IC50 ~ 50000 nM	Poor binder
T86552	Tumor necrosis factor receptor type I	B4TB5Z	(4-{2-Methoxy-4-[(E)-3-(2-methoxy-5-thiophen-2-yl-phenyl)-acryloyl]-phenoxymethyl}-phenyl)-carbamic acid tert-butyl ester	Investigative	44285094	C33H33NO6S	571.7	CC(C)(C)OC(=O)NC1=CC=C(C=C1)COC2=C(C=C(C=C2)C(=O)/C=C/C3=C(C=CC(=C3)C4=CC=CS4)OC)OC	IC50 ~ 50000 nM	Poor binder
T86552	Tumor necrosis factor receptor type I	B79CPZ	(E)-3-(3-Bromo-4,5-dimethoxyphenyl)-1-(3,5-dimethoxy-4-phenylmethoxyphenyl)prop-2-en-1-one	Investigative	44284668	C26H25BrO6	513.4	COC1=CC(=CC(=C1OCC2=CC=CC=C2)OC)C(=O)/C=C/C3=CC(=C(C(=C3)Br)OC)OC	IC50 ~ 50000 nM	Poor binder
T86552	Tumor necrosis factor receptor type I	B9GU2S	(E)-3-[5-(1-Benzothiophen-2-yl)-2,4-dimethoxyphenyl]-1-[4-(cyclopropylmethoxy)-3,5-dimethoxyphenyl]prop-2-en-1-one	Investigative	44284622	C31H30O6S	530.6	COC1=CC(=CC(=C1OCC2CC2)OC)C(=O)/C=C/C3=CC(=C(C=C3OC)OC)C4=CC5=CC=CC=C5S4	IC50 ~ 50000 nM	Poor binder
T86552	Tumor necrosis factor receptor type I	BW06EU	3-(5-Bromo-2-methoxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propan-1-one	Investigative	44284903	C19H21BrO5	409.3	COC1=C(C=C(C=C1)Br)CCC(=O)C2=CC(=C(C(=C2)OC)OC)OC	IC50 ~ 50000 nM	Poor binder