TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86591	Peroxisome proliferator-activated receptor alpha	D05VIX	Gemfibrozil	Approved	3463	C15H22O3	250.33	CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O	EC50 = 59000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	D0J5DC	Clofibrate	Approved	2796	C12H15ClO3	242.7	CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl	EC50 = 55000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	D0NF1U	FENOFIBRIC ACID	Approved	64929	C17H15ClO4	318.7	CC(C)(C(=O)O)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl	IC50 = 68000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B09WSK	(R)-2-(3-(3-(4-Methoxybenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenoxy)butanoic acid	Investigative	11678534	C28H24F3NO6	527.5	CC[C@H](C(=O)O)OC1=CC=CC(=C1)N2C(=C(C3=C2C=C(C=C3)OC(F)(F)F)C(=O)C4=CC=C(C=C4)OC)C	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B0JM7Q	1-(4-Tert-Butyl-phenyl)-3-(3-hydroxy-phenoxy)-1H-indole-2-carboxylic acid	Investigative	44404681	C25H23NO4	401.5	CC(C)(C)C1=CC=C(C=C1)N2C3=CC=CC=C3C(=C2C(=O)O)OC4=CC=CC(=C4)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B0KF1B	3-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-2,2-dimethyl-propionic acid	Investigative	11383635	C19H24F3NO4	387.4	CCCC1=CC2=C(C(=C1OCC(C)(C)C(=O)O)CCC)ON=C2C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B0O3IJ	Plantagineoside B	Investigative	71449654	C31H44O15	656.7	C1=CC(=C(C=C1CCCC[C@@H](CCC2=CC(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O	EC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B0OGD1	Phenylpropanoic acid derivative, 60	Investigative	44263425	C23H26N2O2	362.5	CN(CCCC1=CC=C(C=C1)C[C@@H](C(=O)O)N2C=CC=C2)C3=CC=CC=C3	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B0PFS1	(5r)-5-(3-{[3-(6-Methoxy-1,2-Benzoxazol-3-Yl)-2-Oxo-2,3-Dihydro-1h-Benzimidazol-1-Yl]methyl}phenyl)-5-Methyl-1,3-Oxazolidine-2,4-Dione	Investigative	11591164	C26H20N4O6	484.5	C[C@]1(C(=O)NC(=O)O1)C2=CC=CC(=C2)CN3C4=CC=CC=C4N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1FW4M	2-Phenyl-2-(4-propanoylphenoxy)acetic Acid	Investigative	11448976	C17H16O4	284.31	CCC(=O)C1=CC=C(C=C1)OC(C2=CC=CC=C2)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1I3LA	2-Methyl-2-[4-[2-[4-[(E)-3-phenylprop-2-enoyl]phenoxy]ethyl]phenoxy]propanoic acid	Investigative	71455811	C27H26O5	430.5	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCOC2=CC=C(C=C2)C(=O)/C=C/C3=CC=CC=C3	EC50 = 64000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1M2FY	6-Methoxy-1-oxo-3-phenyl-1H-indene-2-carboxylic acid ethyl ester	Investigative	23249734	C19H16O4	308.3	CCOC(=O)C1=C(C2=C(C1=O)C=C(C=C2)OC)C3=CC=CC=C3	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1VM6C	(S)-2-(3-((3-(4-Methoxybenzoyl)-2,6-dimethyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25165560	C27H26N2O5	458.5	CC1=NC2=C(C=C1)C(=C(N2CC3=CC(=CC=C3)O[C@@H](C)C(=O)O)C)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1W0RQ	(S)-2-(5-Chlorobenzo[d]thiazol-2-ylthio)propanoic acid	Investigative	44478642	C10H8ClNO2S2	273.8	C[C@@H](C(=O)O)SC1=NC2=C(S1)C=CC(=C2)Cl	EC50 = 55900 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1XL0W	(S)-2-(4-Fluoro-3-((6-methoxy-3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25164959	C27H25FN2O6	492.5	CC1=C(C2=C(N1CC3=C(C=CC(=C3)O[C@@H](C)C(=O)O)F)N=C(C=C2)OC)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B1Z0LX	4-[(3R,3As,6R,6aS)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2-methoxyphenol	Investigative	70695728	C20H20O6	356.4	COC1=C(C=CC(=C1)[C@H]2[C@@H]3CO[C@H]([C@@H]3CO2)C4=CC5=C(C=C4)OCO5)O	EC50 = 53200 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B24EYX	5-Chloro-2-[(E)-3-[2-(4-methoxybenzoyl)-4-methylpyrrol-1-yl]prop-1-enyl]-N-methylsulfonylbenzamide	Investigative	9806390	C24H23ClN2O5S	487	CC1=CN(C(=C1)C(=O)C2=CC=C(C=C2)OC)C/C=C/C3=C(C=C(C=C3)Cl)C(=O)NS(=O)(=O)C	EC50 ~ 90000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B28VFR	N-(4-(4-Trifluoromethylbenzyl)carbamoylphenyl)-3-((4R)-2-oxo-4-benzyloxazolidine-3-yl)methylbenzamide	Investigative	90469358	C33H28F3N3O4	587.6	C1[C@H](N(C(=O)O1)CC2=CC(=CC=C2)C(=O)NC3=CC=C(C=C3)C(=O)NCC4=CC=C(C=C4)C(F)(F)F)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B2ANE1	(2R)-2-[2-Chloro-5-[[3-(6-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925995	C26H19ClF3N3O5	545.9	CC1=CC2=C(C=C1)C(=NO2)N3C4=C(C=C(C=C4)C(F)(F)F)N(C3=O)CC5=CC(=C(C=C5)Cl)O[C@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B2NFK6	CID 71721539	Investigative	71721539	C35H39N5O3S	609.8	CCN1C(=NN(C1=O)CC2=CC=C(C=C2)C(C)(C)C)CCCC3=CC=C(C=C3)C4=NC=C(C=C4)NS(=O)(=O)C5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B2TW9I	Pluviatilol	Investigative	70695727	C20H20O6	356.4	COC1=C(C=CC(=C1)[C@@H]2[C@@H]3CO[C@H]([C@@H]3CO2)C4=CC5=C(C=C4)OCO5)O	EC50 ~ 60000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B2Y0UI	(S)-3-(3-Bromo-4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(4-phenylpiperazin-1-yl)propanoic acid	Investigative	11512673	C31H32BrN3O4	590.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=C(C=C(C=C3)C[C@@H](C(=O)O)N4CCN(CC4)C5=CC=CC=C5)Br	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B32PMY	2-[(1S)-5-[3-(2,4-Dimethylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110424	C22H26O4	354.4	CC1=CC(=C(C=C1)OCCCOC2=CC3=C(C=C2)[C@@H](CC3)CC(=O)O)C	EC50 = 106831.67 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B38OKU	2-[4-(3-{[(1S)-1-(Carboxymethyl)-2,3-dihydro-1H-inden-5-yl]oxy}propoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid	Investigative	10434749	C25H25NO6S	467.5	CC1=C(SC(=N1)C2=CC=C(C=C2)OCCCOC3=CC4=C(C=C3)[C@@H](CC4)CC(=O)O)C(=O)O	EC50 = 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B3J4WZ	(2R)-2-[2-Chloro-5-[[3-(5-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925994	C26H19ClF3N3O5	545.9	CC1=CC2=C(C=C1)ON=C2N3C4=C(C=C(C=C4)C(F)(F)F)N(C3=O)CC5=CC(=C(C=C5)Cl)O[C@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B3XV7W	(5R)-5-[3-[[3-(6-Chloro-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	11698802	C25H17ClN4O5	488.9	C[C@]1(C(=O)NC(=O)O1)C2=CC=CC(=C2)CN3C4=CC=CC=C4N(C3=O)C5=NOC6=C5C=CC(=C6)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B3ZU9H	(S)-2-(4-Fluoro-3-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25211572	C26H23FN2O5	462.5	CC1=C(C2=C(N1CC3=C(C=CC(=C3)O[C@@H](C)C(=O)O)F)N=CC=C2)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B46ZGC	1-(4-Tert-Butyl-phenyl)-3-(3-trifluoromethyl-phenoxy)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid	Investigative	44404734	C25H21F3N2O3	454.4	CC(C)(C)C1=CC=C(C=C1)N2C(=C(C3=C2N=CC=C3)OC4=CC=CC(=C4)C(F)(F)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B4A1HC	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-(3-ethoxyphenyl)benzoate	Investigative	44345355	C22H16Cl2LiNO4	436.2	[Li+].CCOC1=CC=CC(=C1)C2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B4HXU3	4-Chloro-N-[2-[4-[1-(methanesulfonamido)-2-methyl-1-oxopropan-2-yl]oxyphenyl]ethyl]benzamide	Investigative	71458514	C20H23ClN2O5S	438.9	CC(C)(C(=O)NS(=O)(=O)C)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl	IC50 = 68500 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B4KE6V	(2S)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926096	C26H19ClF3N3O6	561.9	C[C@@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B4XK6G	(S)-2-(4-Chloro-3-((6-methoxy-3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25165162	C27H25ClN2O6	508.9	CC1=C(C2=C(N1CC3=C(C=CC(=C3)O[C@@H](C)C(=O)O)Cl)N=C(C=C2)OC)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B4XUR7	2-[(1S)-5-[3-(4-Cyanophenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110513	C21H21NO4	351.4	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=CC=C(C=C3)C#N	EC50 = 175428.44 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B4Y3OA	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-(2-pyridin-2-ylethoxy)benzoate	Investigative	44345432	C21H15Cl2LiN2O4	437.2	[Li+].C1=CC=NC(=C1)CCOC2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	Ki ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B50UAG	Trp-glu	Investigative	7009663	C16H19N3O5	333.34	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N	EC50 = 83400 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B51PKN	(2R)-2-[5-[[3-(4-Tert-butylphenyl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]-2-chlorophenoxy]propanoic acid	Investigative	56925893	C28H26ClF3N2O4	547	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=CC=C(C=C4)C(C)(C)C)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B58ARF	2-[(1S)-5-[3-[4-(1H-Indol-6-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110438	C28H27NO4	441.5	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=CC=C(C=C3)C4=CC5=C(C=C4)C=CN5	EC50 = 151530.48 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5G3NQ	Phenylpropanoic acid derivative, 32	Investigative	44263418	C22H21N3O2	359.4	CN(CC#CC1=CC=C(C=C1)CC(C(=O)O)N2C=CC=C2)C3=CC=CC=N3	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5OHR7	2-[3-[(4-Methylphenyl)carbamoyl]-4-piperidin-1-ylphenyl]indazole-6-carboxylic acid	Investigative	102004339	C27H26N4O3	454.5	CC1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)N3C=C4C=CC(=CC4=N3)C(=O)O)N5CCCCC5	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5PNJ6	(S)-2-(4-Chloro-3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25165638	C24H20Cl2N2O4	471.3	CC1=C(C2=C(N1CC3=C(C=CC(=C3)O[C@@H](C)C(=O)O)Cl)N=CC=C2)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5VXB7	(S)-2-(4-Chloro-3-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25166740	C24H19Cl2FN2O4	489.3	CC1=C(C2=C(N1CC3=C(C=CC(=C3)O[C@@H](C)C(=O)O)Cl)N=C(C=C2)F)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5XPI0	2-[4-(2-Hydroxyethyl)phenoxy]-2-methylpropanoic acid	Investigative	68811733	C12H16O4	224.25	CC(C)(C(=O)O)OC1=CC=C(C=C1)CCO	EC50 = 75100 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5Z4RJ	2-[4-(3-{[(1S)-1-(Carboxymethyl)-2,3-dihydro-1h-inden-5-yl]oxy}propoxy)-3-methoxyphenyl]-4-methyl-1,3-thiazole-5-carboxylic acid	Investigative	16110532	C26H27NO7S	497.6	CC1=C(SC(=N1)C2=CC(=C(C=C2)OCCCOC3=CC4=C(C=C3)[C@@H](CC4)CC(=O)O)OC)C(=O)O	EC50 = 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B5ZQ7N	(5R)-5-[3-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	11563028	C27H19F3N4O6	552.5	C[C@]1(C(=O)NC(=O)O1)C2=CC=CC(=C2)CN3C4=C(C=CC(=C4)C(F)(F)F)N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B65ZKA	Lithium;5-(6-chloropyrazin-2-yl)oxy-2-[(2,4-dichlorobenzoyl)amino]benzoate	Investigative	44345158	C18H9Cl3LiN3O4	444.6	[Li+].C1=CC(=C(C=C1OC2=CN=CC(=N2)Cl)C(=O)[O-])NC(=O)C3=C(C=C(C=C3)Cl)Cl	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B69GRM	N-(4-Acetamidophenyl)sulfonyl-2-[(5-chloro-1,3-benzothiazol-2-yl)sulfanyl]pentanamide	Investigative	127033833	C20H20ClN3O4S3	498	CCCC(C(=O)NS(=O)(=O)C1=CC=C(C=C1)NC(=O)C)SC2=NC3=C(S2)C=CC(=C3)Cl	IC50 = 108000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B6F8AT	(2R)-2-[2-Chloro-5-[[3-[(4-chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925781	C25H19Cl2F3N2O4	539.3	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)CC4=CC=C(C=C4)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B6I9KZ	(4-Isopropyl-phenyl)-(4-propionyl-2,6-dipropyl-phenylamino)-acetic acid	Investigative	11463996	C26H35NO3	409.6	CCCC1=CC(=CC(=C1NC(C2=CC=C(C=C2)C(C)C)C(=O)O)CCC)C(=O)CC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B6PH3J	Rac-2-[(6-Bromo-1,3-benzothiazol-2-yl)thio]propanoic Acid	Investigative	44479187	C10H8BrNO2S2	318.2	CC(C(=O)O)SC1=NC2=C(S1)C=C(C=C2)Br	EC50 = 84300 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B76ASC	(2R)-3,3,3-Trifluoro-2-[5-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylthiophen-2-yl]-2-hydroxypropanamide	Investigative	49846481	C19H18F7N3O4S2	549.5	C[C@@H]1CN(CCN1S(=O)(=O)C2=CC=C(S2)[C@@](C(=O)N)(C(F)(F)F)O)C3=C(C=C(C=C3)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B7E5KU	5-Benzyl-2-Ethyl-3-{(1s)-5-[2-(1h-Tetrazol-5-Yl)phenyl]-2,3-Dihydro-1h-Inden-1-Yl}-3,5-Dihydro-4h-Imidazo[4,5-C]pyridin-4-One	Investigative	46184983	C31H27N7O	513.6	CCC1=NC2=C(N1[C@H]3CCC4=C3C=CC(=C4)C5=CC=CC=C5C6=NNN=N6)C(=O)N(C=C2)CC7=CC=CC=C7	EC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B7NGP8	(2R)-2-[2-Chloro-5-[[3-(4-chlorobenzoyl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925892	C25H17Cl2F3N2O5	553.3	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C(=O)C4=CC=C(C=C4)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B7SHP9	2-[(1S)-5-{3-[4-(Pyrimidin-5-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110441	C24H24N2O4	404.5	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=CC=C(C=C3)C4=CN=CN=C4	EC50 = 137372.56 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B89XOI	1-(4-Tert-Butyl-phenyl)-6-chloro-3-(3-methanesulfonyl-phenoxy)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid	Investigative	44404649	C25H23ClN2O5S	499	CC(C)(C)C1=CC=C(C=C1)N2C(=C(C3=C2N=C(C=C3)Cl)OC4=CC(=CC=C4)S(=O)(=O)C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B8PJU2	1-(4-Methoxy-phenyl)-3-(3-trifluoromethyl-phenoxy)-1H-indole-2-carboxylic acid	Investigative	44404685	C23H16F3NO4	427.4	COC1=CC=C(C=C1)N2C3=CC=CC=C3C(=C2C(=O)O)OC4=CC=CC(=C4)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B8Y9FN	Epipinoresinol	Investigative	637584	C20H22O6	358.4	COC1=C(C=CC(=C1)[C@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=CC(=C(C=C4)O)OC)O	EC50 ~ 60000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B95UCY	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-(3-nitropyridin-2-yl)oxybenzoate	Investigative	44345159	C19H10Cl2LiN3O6	454.2	[Li+].C1=CC(=C(N=C1)OC2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-])[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B9D3PR	(R)-2-(5-Methoxybenzo[d]thiazol-2-ylthio)propanoic acid	Investigative	44478643	C11H11NO3S2	269.3	C[C@H](C(=O)O)SC1=NC2=C(S1)C=CC(=C2)OC	EC50 = 57300 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B9H3NR	3-[[(4R)-4-Benzyl-2-oxo-1,3-oxazolidin-3-yl]methyl]-N-[4-(cyclohexylmethylcarbamoyl)phenyl]benzamide	Investigative	90469424	C32H35N3O4	525.6	C1CCC(CC1)CNC(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC(=C3)CN4[C@@H](COC4=O)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B9LSJ1	(2R)-3-[4-[3-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)propyl]phenyl]-2-(triazol-1-yl)propanoic acid	Investigative	46228281	C24H24N4O3	416.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCCC3=CC=C(C=C3)C[C@H](C(=O)O)N4C=CN=N4	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	B9MAY7	1-(4-Tert-Butyl-phenyl)-3-(3-ethoxy-phenoxy)-1H-indole-2-carboxylic acid	Investigative	44404680	C27H27NO4	429.5	CCOC1=CC(=CC=C1)OC2=C(N(C3=CC=CC=C32)C4=CC=C(C=C4)C(C)(C)C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BA21GD	2-[(6-Ethoxy-1,3-benzothiazol-2-yl)thio]-2-methylpropanoic Acid	Investigative	44479184	C13H15NO3S2	297.4	CCOC1=CC2=C(C=C1)N=C(S2)SC(C)(C)C(=O)O	EC50 = 69300 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BAE4Y0	(5R)-5-[4-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	56926187	C27H19F3N4O6	552.5	C[C@]1(C(=O)NC(=O)O1)C2=CC=C(C=C2)CN3C4=C(C=CC(=C4)C(F)(F)F)N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BAUN46	2,2-Dimethyl-5-[4-[(E)-2-naphthalen-2-ylethenyl]phenoxy]pentanoic acid	Investigative	127037376	C25H26O3	374.5	CC(C)(CCCOC1=CC=C(C=C1)/C=C/C2=CC3=CC=CC=C3C=C2)C(=O)O	EC50 = 90000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BB8JS2	(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925997	C26H19ClF3N3O6	561.9	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BBI15A	(2R)-2-[2-Chloro-5-[[3-(6-chloro-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925895	C25H16Cl2F3N3O5	566.3	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BBR97V	(2R)-2-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926097	C26H19ClF3N3O6	561.9	C[C@H](C(=O)O)OC1=CC(=C(C=C1)Cl)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BCQ12P	(S)-2-(2-Chloro-5-((6-chloro-3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25166956	C24H19Cl3N2O4	505.8	CC1=C(C2=C(N1CC3=CC(=C(C=C3)Cl)O[C@@H](C)C(=O)O)N=C(C=C2)Cl)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BD73SY	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-[(4-ethoxyphenyl)methoxy]benzoate	Investigative	44345354	C23H18Cl2LiNO5	466.3	[Li+].CCOC1=CC=C(C=C1)COC2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	Ki ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BDKR45	(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethoxy)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925998	C26H19ClF3N3O7	577.9	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)OC(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BEJ15H	(2R)-2-[3-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]butanoic acid	Investigative	56926185	C27H22F3N3O6	541.5	CC[C@H](C(=O)O)OC1=CC=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BEL79Y	(2R)-2-[3-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926098	C26H20F3N3O6	527.4	C[C@H](C(=O)O)OC1=CC=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BF09GY	(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(4-p-tolylpiperazin-1-yl)propanoic acid	Investigative	46884868	C32H35N3O4	525.6	CC1=CC=C(C=C1)N2CCN(CC2)[C@@H](CC3=CC=C(C=C3)OCCC4=C(OC(=N4)C5=CC=CC=C5)C)C(=O)O	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BF49OK	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-(5-nitropyridin-2-yl)oxybenzoate	Investigative	44345170	C19H10Cl2LiN3O6	454.2	[Li+].C1=CC(=C(C=C1OC2=NC=C(C=C2)[N+](=O)[O-])C(=O)[O-])NC(=O)C3=C(C=C(C=C3)Cl)Cl	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BG45IK	(5R)-5-[3-[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	56926188	C26H17F3N4O6	538.4	C[C@]1(C(=O)NC(=O)O1)C2=CC(=CC=C2)N3C4=C(C=CC(=C4)C(F)(F)F)N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BG4B3N	(S)-2-(2-Chloro-5-((6-methoxy-3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25165359	C27H25ClN2O6	508.9	CC1=C(C2=C(N1CC3=CC(=C(C=C3)Cl)O[C@@H](C)C(=O)O)N=C(C=C2)OC)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BG4MB8	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-quinolin-8-ylbenzoate	Investigative	44345180	C23H13Cl2LiN2O3	443.2	[Li+].C1=CC2=C(C(=C1)C3=CC(=C(C=C3)NC(=O)C4=C(C=C(C=C4)Cl)Cl)C(=O)[O-])N=CC=C2	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BG7I8C	(2R,3R,4S,5S,6R)-2-[(3R,5R)-1,7-Bis(3,4-dihydroxyphenyl)-5-hydroxyheptan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	10896495	C25H34O11	510.5	C1=CC(=C(C=C1CC[C@H](C[C@@H](CCC2=CC(=C(C=C2)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O	EC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BG9RV3	CID 11592357	Investigative	11592357	C27H18ClF3N4O6	586.9	C[C@]1(C(=O)NC(=O)O1)C2=CC(=C(C=C2)Cl)CN3C4=C(C=CC(=C4)C(F)(F)F)N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BGHW31	2-[(1S)-5-{3-[2-Acetamido-4-(1H-1,2,3-triazol-1-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110519	C24H26N4O5	450.5	CC(=O)NC1=C(C=CC(=C1)N2C=CN=N2)OCCCOC3=CC4=C(C=C3)[C@@H](CC4)CC(=O)O	EC50 = 108692.61 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BGQF10	1-(4-Tert-Butyl-phenyl)-6-chloro-3-[3-(4-trifluoromethyl-1H-pyrrol-2-yl)-phenoxy]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid	Investigative	44404654	C29H23ClF3N3O3	554	CC(C)(C)C1=CC=C(C=C1)N2C(=C(C3=C2N=C(C=C3)Cl)OC4=CC=CC(=C4)C5=CC(=CN5)C(F)(F)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BH0BC9	(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926189	C25H20ClN3O6	493.9	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=CC=CC=C3N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BHN69X	(2R)-2-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926276	C25H20ClN3O6	493.9	C[C@H](C(=O)O)OC1=CC(=C(C=C1)Cl)CN2C3=CC=CC=C3N(C2=O)C4=NOC5=C4C=CC(=C5)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BI0ZF6	(S)-2-(2-Chloro-5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	25166741	C24H19Cl2FN2O4	489.3	CC1=C(C2=C(N1CC3=CC(=C(C=C3)Cl)O[C@@H](C)C(=O)O)N=C(C=C2)F)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BI7BX5	(5R)-5-[2-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	56926186	C27H19F3N4O6	552.5	C[C@]1(C(=O)NC(=O)O1)C2=CC=CC=C2CN3C4=C(C=CC(=C4)C(F)(F)F)N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BJ15DO	5-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-phenyl-2H-1,2,3-triazole-4-carboxylic acid	Investigative	23402831	C27H22N4O4	466.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=CC=C(C=C3)C4=NN(N=C4C(=O)O)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BJ7EK4	Phenylpropanoic acid derivative, 33	Investigative	44263419	C23H22N2O2	358.4	CN(CC#CC1=CC=C(C=C1)C[C@@H](C(=O)O)N2C=CC=C2)C3=CC=CC=C3	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BJU2Z5	1-(4-Tert-Butyl-phenyl)-5-hydroxy-3-(3-trifluoromethyl-phenoxy)-1H-indole-2-carboxylic acid	Investigative	44404717	C26H22F3NO4	469.5	CC(C)(C)C1=CC=C(C=C1)N2C3=C(C=C(C=C3)O)C(=C2C(=O)O)OC4=CC=CC(=C4)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BK2BJ8	3-[[(4S)-4-Benzyl-2-oxo-1,3-oxazolidin-3-yl]methyl]-N-[4-[[4-(trifluoromethyl)phenyl]methylcarbamoyl]phenyl]benzamide	Investigative	122184718	C33H28F3N3O4	587.6	C1[C@@H](N(C(=O)O1)CC2=CC(=CC=C2)C(=O)NC3=CC=C(C=C3)C(=O)NCC4=CC=C(C=C4)C(F)(F)F)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BK2F9P	(S)-3-(3-((E)-1-(4-Hydroxybenzyloxyimino)ethyl)phenyl)-2-ethoxypropanoicAcid	Investigative	25115099	C20H23NO5	357.4	CCO[C@@H](CC1=CC(=CC=C1)/C(=N/OCC2=CC=C(C=C2)O)/C)C(=O)O	EC50 = 58800 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BK9D2C	2-[(1S)-5-{3-[2-Chloro-4-(4H-1,2,4-triazol-4-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110429	C22H22ClN3O4	427.9	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=C(C=C(C=C3)N4C=NN=C4)Cl	EC50 = 145982.23 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BKW3N2	N-(4-Benzylcarbamoylphenyl)-3-((4R)-2-oxo-4-benzyloxazolidine-3-yl)methylbenzamide	Investigative	90469423	C32H29N3O4	519.6	C1[C@H](N(C(=O)O1)CC2=CC(=CC=C2)C(=O)NC3=CC=C(C=C3)C(=O)NCC4=CC=CC=C4)CC5=CC=CC=C5	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BL7B5I	2-[(5-Chlorobenzothiazole)-2-ylthio]propanoic acid	Investigative	44479185	C10H8ClNO2S2	273.8	CC(C(=O)O)SC1=NC2=C(S1)C=CC(=C2)Cl	EC50 = 62500 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BL8C0Y	(S)-7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid	Investigative	10116365	C22H22ClF3O6	474.9	C[C@]1(CCC2=C(O1)C=C(C=C2)OCCCOC3=C(C=C(C=C3)OCC(F)(F)F)Cl)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BLI89H	(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-5-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926094	C26H19ClF3N3O6	561.9	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=C(C=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BLK1A5	(S)-2-(2-Fluoro-5-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	44561817	C26H23FN2O5	462.5	CC1=C(C2=C(N1CC3=CC(=C(C=C3)F)O[C@@H](C)C(=O)O)N=CC=C2)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BME42I	Lithium;5-(3-carboxyphenyl)-2-[(2,4-dichlorobenzoyl)amino]benzoate	Investigative	44345171	C21H12Cl2LiNO5	436.2	[Li+].C1=CC(=CC(=C1)C(=O)O)C2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	Ki = 67000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BMQG94	N-(Benzenesulfonyl)-2-[(5-chloro-1,3-benzothiazol-2-yl)sulfanyl]octanamide	Investigative	53380705	C21H23ClN2O3S3	483.1	CCCCCCC(C(=O)NS(=O)(=O)C1=CC=CC=C1)SC2=NC3=C(S2)C=CC(=C3)Cl	EC50 = 50600 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BN68QD	(S)-2-(2-Chloro-5-((3-(4-chlorophenoxy)-2-methyl-6-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	44561969	C25H19Cl2F3N2O4	539.3	CC1=C(C2=C(N1CC3=CC(=C(C=C3)Cl)O[C@@H](C)C(=O)O)N=C(C=C2)C(F)(F)F)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BN90CQ	(S)-2-(3-((3-(4-Chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-4-fluorophenoxy)propanoic acid	Investigative	25165639	C24H20ClFN2O4	454.9	CC1=C(C2=C(N1CC3=C(C=CC(=C3)O[C@@H](C)C(=O)O)F)N=CC=C2)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BN9AJ7	(S)-2-(3-((3-(4-Methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid	Investigative	44561816	C26H24N2O5	444.5	CC1=C(C2=C(N1CC3=CC(=CC=C3)O[C@@H](C)C(=O)O)N=CC=C2)C(=O)C4=CC=C(C=C4)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BN9CL4	2,2-Dimethyl-5-[4-[(E)-3-phenylprop-2-enoyl]phenoxy]pentanoic acid	Investigative	56641379	C22H24O4	352.4	CC(C)(CCCOC1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2)C(=O)O	EC50 = 61500 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BO3T1L	(3S,4S)-4-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-[4-(trifluoromethyl)pyrimidin-2-yl]pyrrolidine-3-carboxylic acid	Investigative	58977737	C29H27F3N4O4	552.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=CC=C(C=C3)C[C@@H]4CN(C[C@H]4C(=O)O)C5=NC=CC(=N5)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BO53VG	(S)-2-(4-(3-Chlorophenyl)piperazin-1-yl)-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid	Investigative	11570226	C31H32ClN3O4	546.1	CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=CC=C(C=C3)C[C@@H](C(=O)O)N4CCN(CC4)C5=CC(=CC=C5)Cl	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BO8G0A	(5R)-5-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione	Investigative	11620575	C26H19ClN4O6	518.9	C[C@]1(C(=O)NC(=O)O1)C2=CC(=C(C=C2)Cl)CN3C4=CC=CC=C4N(C3=O)C5=NOC6=C5C=CC(=C6)OC	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BOE89X	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-(2-thiophen-2-ylethoxy)benzoate	Investigative	44345204	C20H14Cl2LiNO4S	442.3	[Li+].C1=CSC(=C1)CCOC2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	Ki ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BPLK05	2,2-Dimethyl-5-[4-[(E)-2-pyridin-4-ylethenyl]phenoxy]pentanoic acid	Investigative	127037541	C20H23NO3	325.4	CC(C)(CCCOC1=CC=C(C=C1)/C=C/C2=CC=NC=C2)C(=O)O	EC50 = 103200 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BQ52HR	Lithium;2-[(2,4-dichlorobenzoyl)amino]-5-pyrimidin-2-yloxybenzoate	Investigative	44345164	C18H10Cl2LiN3O4	410.2	[Li+].C1=CN=C(N=C1)OC2=CC(=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C(=O)[O-]	Ki ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BQ89ZW	(2R,3R,4S,5S,6R)-2-[(3R,5R)-5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	10896097	C25H34O9	478.5	C1=CC(=CC=C1CC[C@H](C[C@@H](CCC2=CC=C(C=C2)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O	EC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BQZ24D	(2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}pentanoic Acid	Investigative	44190764	C29H25ClF3NO5	560	CCC[C@@H](C(=O)O)OC1=CC=CC(=C1)CN2C(=C(C3=C2C=C(C=C3)OC(F)(F)F)C(=O)C4=CC=C(C=C4)Cl)C	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BR3NQ1	(S)-2-(5-((3-(4-Chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-2-fluorophenoxy)propanoic acid	Investigative	25166738	C24H20ClFN2O4	454.9	CC1=C(C2=C(N1CC3=CC(=C(C=C3)F)O[C@@H](C)C(=O)O)N=CC=C2)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BR42FN	1-(4-Tert-Butyl-phenyl)-3-[4-(4-trifluoromethyl-1H-pyrrol-2-yl)-phenoxy]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid	Investigative	44404735	C29H24F3N3O3	519.5	CC(C)(C)C1=CC=C(C=C1)N2C(=C(C3=C2N=CC=C3)OC4=CC=C(C=C4)C5=CC(=CN5)C(F)(F)F)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BR7X4C	(2R)-2-[2-Chloro-5-[[3-(7-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925896	C26H19ClF3N3O5	545.9	CC1=C2C(=CC=C1)C(=NO2)N3C4=C(C=C(C=C4)C(F)(F)F)N(C3=O)CC5=CC(=C(C=C5)Cl)O[C@H](C)C(=O)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BRK69Y	(S)-2-(5-((3-(4-Chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-2-fluorophenoxy)propanoic acid	Investigative	25166743	C24H19ClF2N2O4	472.9	CC1=C(C2=C(N1CC3=CC(=C(C=C3)F)O[C@@H](C)C(=O)O)N=C(C=C2)F)OC4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BS8A4X	N-(4-Pentylcarbamoylphenyl)-3-((4S)-2-oxo-4-benzyloxazolidine-3-yl)methylbenzamide	Investigative	122184719	C30H33N3O4	499.6	CCCCCNC(=O)C1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CN3[C@H](COC3=O)CC4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BTE74Y	Plantagineoside C	Investigative	71455005	C25H32O11	508.5	C1[C@H](C[C@H](O[C@H]1CCC2=CC(=C(C=C2)O)O)C3=CC(=C(C=C3)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O	EC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BU4Z6L	(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-5-(trifluoromethoxy)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56926095	C26H19ClF3N3O7	577.9	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=C(C=C3)OC(F)(F)F)N(C2=O)C4=NOC5=C4C=CC(=C5)OC)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BU60CA	3-(3-Hydroxy-phenoxy)-1-(3-isopropyl-phenyl)-1H-indole-2-carboxylic acid	Investigative	44404696	C24H21NO4	387.4	CC(C)C1=CC(=CC=C1)N2C3=CC=CC=C3C(=C2C(=O)O)OC4=CC=CC(=C4)O	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BU8QJ3	(2R)-2-[2-Chloro-5-[[3-(6-chloro-1,3-benzothiazol-2-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925894	C25H16Cl2F3N3O4S	582.4	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NC5=C(S4)C=C(C=C5)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BUDC19	(R)-2-(5-Chlorobenzo[d]thiazol-2-ylthio)propanoic acid	Investigative	44479442	C10H8ClNO2S2	273.8	C[C@H](C(=O)O)SC1=NC2=C(S1)C=CC(=C2)Cl	EC50 = 73500 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BV5A4Y	(2R)-2-[2-Chloro-5-[[3-(5-chloro-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid	Investigative	56925996	C25H16Cl2F3N3O5	566.3	C[C@H](C(=O)O)OC1=C(C=CC(=C1)CN2C3=C(C=CC(=C3)C(F)(F)F)N(C2=O)C4=NOC5=C4C=C(C=C5)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BVKZ70	4-[(3R,3Ar,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2,6-dimethoxyphenol	Investigative	57404419	C21H22O7	386.4	COC1=CC(=CC(=C1O)OC)[C@@H]2[C@H]3CO[C@H]([C@H]3CO2)C4=CC5=C(C=C4)OCO5	EC50 ~ 60000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BW2G7L	(2R)-3-[4-[3-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)propyl]phenyl]-2-(1,2,4-triazol-1-yl)propanoic acid	Investigative	46228280	C24H24N4O3	416.5	CC1=C(N=C(O1)C2=CC=CC=C2)CCCC3=CC=C(C=C3)C[C@H](C(=O)O)N4C=NC=N4	EC50 ~ 100000 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BW3FL2	7-Chloro-8-methyl-2-phenylquinoline-4-carboxylic acid	Investigative	237084	C17H12ClNO2	297.7	CC1=C(C=CC2=C1N=C(C=C2C(=O)O)C3=CC=CC=C3)Cl	EC50 = 52400 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BX1F6B	2-[4-(3-{[(1S)-1-(Carboxymethyl)-2,3-dihydro-1h-inden-5-yl]oxy}propoxy)-3-propylphenyl]-4-(hydroxymethyl)-1,3-thiazole-5-carboxylic acid	Investigative	16110492	C28H31NO7S	525.6	CCCC1=C(C=CC(=C1)C2=NC(=C(S2)C(=O)O)CO)OCCCOC3=CC4=C(C=C3)[C@@H](CC4)CC(=O)O	EC50 = 154099.06 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BY0AD5	2-[(1S)-5-[3-(4-Cyano-2-methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110427	C22H23NO5	381.4	COC1=C(C=CC(=C1)C#N)OCCCOC2=CC3=C(C=C2)[C@@H](CC3)CC(=O)O	EC50 = 127320.99 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BY13US	2-[(1S)-5-[3-[4-(Trifluoromethoxy)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid	Investigative	16110512	C21H21F3O5	410.4	C1CC2=C([C@@H]1CC(=O)O)C=CC(=C2)OCCCOC3=CC=C(C=C3)OC(F)(F)F	EC50 = 147061.84 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	BY2G6K	5-[4-[(E)-3-Phenylprop-2-enoyl]phenoxy]pentanoic acid	Investigative	56641248	C20H20O4	324.4	C1=CC=C(C=C1)/C=C/C(=O)C2=CC=C(C=C2)OCCCCC(=O)O	EC50 = 109300 nM	Poor binder
T86591	Peroxisome proliferator-activated receptor alpha	D04DYM	GW1929	Investigative	6518171	C30H29N3O4	495.6	CN(CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4	EC50 = 55300 nM	Poor binder