TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86702	Matrix metalloproteinase-3	D0G1LL	1607004-34-1	Patented	74221072	C20H22F3N3O3	409.4	C1CC1[C@H](CC2=CC=C(C=C2)C(F)(F)F)C(=O)NC[C@@]3(C(=O)NC(=O)N3)C4CC4	IC50 = 99710 nM	Poor binder
T86702	Matrix metalloproteinase-3	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B03XNO	(4S)-5-[3-(Carboxymethyl)piperidin-1-yl]-5-oxo-4-[3-(4-thiophen-2-ylphenyl)propanoylamino]pentanoic acid	Investigative	50991513	C25H30N2O6S	486.6	C1CC(CN(C1)C(=O)[C@H](CCC(=O)O)NC(=O)CCC2=CC=C(C=C2)C3=CC=CS3)CC(=O)O	Ki ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B09XSF	Hydroxamate deriv., 78	Investigative	24799779	C23H23N3O4	405.4	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)C[C@@]4(C[C@@H]4C(=O)NO)C(=O)N	Ki = 58000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B0DQ4U	(2S)-2-[[(2S)-2-[[(2R)-2-Aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-phenylpentanamide	Investigative	44356805	C24H32N4O3	424.5	C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)NC2=CC=CC=C2)N	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B0IWY1	Isoacteoside	Investigative	6476333	C29H36O15	624.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2[C@@H]([C@H](O[C@H]([C@@H]2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)/C=C/C4=CC(=C(C=C4)O)O)O)O)O)O	IC50 = 91410 nM	Poor binder
T86702	Matrix metalloproteinase-3	B0J4RS	(R)-2-(N-Isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid	Investigative	45482676	C20H25NO5S	391.5	CC(C)[C@H](C(=O)O)N(OC(C)C)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2	IC50 = 54000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B0MUP5	2-(4-Chlorophenoxy)-N-{[(4r)-4-Methyl-2,5-Dioxoimidazolidin-4-Yl]methyl}acetamide	Investigative	86287514	C13H14ClN3O4	311.72	C[C@]1(C(=O)NC(=O)N1)CNC(=O)COC2=CC=C(C=C2)Cl	IC50 = 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B0QR5V	3-(Hydroxymethyl)-6-(4-hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethynyl]benzoic acid	Investigative	122179777	C22H16O5	360.4	C1=CC(=CC=C1C#CC2=C(C=CC(=C2C(=O)O)C3=CC=C(C=C3)O)CO)O	IC50 = 82560 nM	Poor binder
T86702	Matrix metalloproteinase-3	B12CRJ	N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide	Investigative	22096205	C16H31N3O4	329.43	CCCCC(CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B1B7TI	Chembl4208066	Investigative	145976464	C31H22O5	474.5	C1=CC(=CC=C1C2=CC(=CC(=C2C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)C(=O)C5=CC=C(C=C5)O)O	IC50 = 66120 nM	Poor binder
T86702	Matrix metalloproteinase-3	B1YM9Q	(Methylamino)carbonylphosphonic acid	Investigative	11457732	C2H6NO4P	139.05	CNC(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B1ZH3O	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-1-hydroxyurea	Investigative	44286406	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCN(C(=O)N)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B25XRZ	Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid	Investigative	9817594	C12H27N2O4P	294.33	CC(C)CCNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B26QZF	1-(4-Methoxy-phenyl)-3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-urea	Investigative	10636628	C10H10N4O2S2	282.3	COC1=CC=C(C=C1)NC(=O)NC2=NNC(=S)S2	Ki = 69000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 = 78000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B3T2HA	Chembl4215193	Investigative	145972073	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B41JRW	Berkchaetoazaphilone A	Investigative	127028674	C25H34O6	430.5	CCCCCCCCCC(=O)[C@H]1[C@@H]2C3=COC(=CC3=CC(=O)[C@@]2(OC1=O)C)C[C@H](C)O	IC50 = 130000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B46JHV	Chembl4206592	Investigative	46873064	C27H20O6	440.4	C1=CC(=CC=C1C2=C3C(=C(C=C2)CO)C(=O)OC3(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O)O	IC50 = 87770 nM	Poor binder
T86702	Matrix metalloproteinase-3	B52VLK	N-[1-(Phenoxymethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid	Investigative	21700204	C23H20N2O4	388.4	C1=CC=C(C=C1)OCC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O	IC50 = 130000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B5AB4X	(Propylamino)carbonylphosphonic acid	Investigative	11400989	C4H10NO4P	167.1	CCCNC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B69FKU	Chembl4208646	Investigative	46840956	C31H22O10	554.5	COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)O)O)O	IC50 = 74340 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 = 76000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6IN8S	Sodium hydrogen (butylamino)carbonylphosphonate	Investigative	23692637	C5H11NNaO4P	203.11	CCCCNC(=O)P(=O)(O)[O-].[Na+]	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6L5WX	Berkeleylactone A	Investigative	132967549	C19H32O7S	404.5	C[C@@H]1CCCCCCCCC[C@@H](C(=O)C[C@H](C(=O)O1)SC[C@H](C(=O)O)O)O	IC50 = 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6QZN9	Chembl4214716	Investigative	145971807	C50H52Cl2F2N4O5S	929.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=C(C=C5)F)Cl)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=C(C=C7)F)Cl	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6W3HR	Chembl4202989	Investigative	145978450	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 = 58300 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6WC8Y	N-[1-[4-(4-Cyanophenyl)phenoxy]-3-(4-fluorophenyl)propan-2-yl]-N-hydroxyformamide	Investigative	21699983	C23H19FN2O3	390.4	C1=CC(=CC=C1CC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O)F	IC50 = 180000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B6YT2H	(S)-2-((E)-3-Furan-2-yl-acryloylamino)-3-(1H-indol-3-yl)-propionic acid	Investigative	40424573	C18H16N2O4	324.3	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)/C=C/C3=CC=CO3	Ki = 120000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B71YOW	N-[1-(4'-Cyano-4-biphenylyloxymethyl)-3-methylbutyl]formhydroxamic acid	Investigative	21700004	C20H22N2O3	338.4	CC(C)CC(COC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)N(C=O)O	IC50 = 120000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B7PA0B	5-(2-Chloro-6-methyl-phenylamino)-3H-[1,3,4]thiadiazole-2-thione	Investigative	44285343	C9H8ClN3S2	257.8	CC1=C(C(=CC=C1)Cl)NC2=NNC(=S)S2	IC50 = 173000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B87SHX	N-[[(4S)-4-(1-Methylimidazol-2-yl)-2,5-dioxoimidazolidin-4-yl]methyl]-5-(trifluoromethyl)-1-benzofuran-2-carboxamide	Investigative	101910871	C18H14F3N5O4	421.3	CN1C=CN=C1[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)C(F)(F)F	IC50 = 69000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B8DC0N	Cyclooctylcarbamoylphosphonic Acid	Investigative	11817193	C9H18NO4P	235.22	C1CCCC(CCC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B8JE1T	3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid	Investigative	4085085	C19H12N2O4S	364.4	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN(C(=S)N3)C4=CC=CC(=C4)C(=O)O	IC50 = 110000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B8QGP0	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036769	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC=C(C=C4)[N+](=O)[O-])/S3	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B8TI3E	Boc-Trp-OSu	Investigative	98767	C20H23N3O6	401.4	CC(C)(C)OC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)ON3C(=O)CCC3=O	Ki = 84000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B96EBG	Carbobenzoxyphenylalanine	Investigative	70878	C17H17NO4	299.32	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)OCC2=CC=CC=C2	Ki = 83000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B9KGM5	5-Chloro-N-[[(4S)-4-(2-methylpyrazol-3-yl)-2,5-dioxoimidazolidin-4-yl]methyl]-1-benzofuran-2-carboxamide	Investigative	118722688	C17H14ClN5O4	387.8	CN1C(=CC=N1)[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)Cl	IC50 = 64000 nM	Poor binder
T86702	Matrix metalloproteinase-3	B9MR1L	(R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamoyl)-nonadecanoic acid	Investigative	10394828	C30H50N2O4	502.7	CCCCCCCCCCCCCCCC[C@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC	IC50 = 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BAN7Z4	(Cycloheptylamino)carbonylphosphonic acid	Investigative	11447356	C8H16NO4P	221.19	C1CCCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BBF3R4	(Cyclopropylamino)carbonylphosphonic acid	Investigative	11252195	C4H8NO4P	165.08	C1CC1NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 77000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BD36TG	Chembl4203061	Investigative	145977013	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)F	IC50 = 59700 nM	Poor binder
T86702	Matrix metalloproteinase-3	BD57BI	Chembl4211700	Investigative	145963891	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 = 52800 nM	Poor binder
T86702	Matrix metalloproteinase-3	BD85MN	(5Z)-5-[4-(Benzyloxy)benzylidene]-2-thioxo-1,3-thiazolidin-4-one	Investigative	1204907	C17H13NO2S2	327.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C\\3/C(=O)NC(=S)S3	IC50 = 77430 nM	Poor binder
T86702	Matrix metalloproteinase-3	BDX1T5	(S)-2-Tert-Butoxycarbonylamino-3-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-propionic acid	Investigative	13875965	C25H30N2O6S	486.6	CC1=CC(=C(C(=C1)C)S(=O)(=O)N2C=C(C3=CC=CC=C32)C[C@@H](C(=O)O)NC(=O)OC(C)(C)C)C	Ki = 52000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BE06IA	Chembl4282646	Investigative	132967554	C16H28O5	300.39	C[C@@H]1[C@H](CCCCCCCC[C@@H]([C@@H](/C=C/C(=O)O1)O)O)O	IC50 = 150000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BEUF79	(2R)-N-Hydroxy-4-methyl-2-[[methyl(phenyl)phosphoryl]amino]pentanamide	Investigative	10541018	C13H21N2O3P	284.29	CC(C)C[C@H](C(=O)NO)N[P@](=O)(C)C1=CC=CC=C1	IC50 = 130500 nM	Poor binder
T86702	Matrix metalloproteinase-3	BF6ZI1	N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide	Investigative	44479458	C20H17NO6S2	431.5	CS(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 60000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BFQS36	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-chlorophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036768	C17H10ClN3OS2	371.9	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC=C(C=C4)Cl)/S3	IC50 = 65000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BG7P3F	Cyclohexanamine;2-methylpropylcarbamoylphosphonic acid	Investigative	9882151	C11H25N2O4P	280.3	CC(C)CNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BG91IE	5-Dodecylamino-3H-[1,3,4]thiadiazole-2-thione	Investigative	44285686	C14H27N3S2	301.5	CCCCCCCCCCCCNC1=NNC(=S)S1	IC50 = 97000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 = 80000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BHK6A7	(2R)-2-Amino-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	44356667	C21H34N4O3	390.5	CC(C)C[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)N	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BIT3C5	(4S)-5-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]amino]-5-oxo-4-[3-(4-phenylphenyl)propanoylamino]pentanoic acid	Investigative	50992325	C26H33N3O5	467.6	CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CCC1=CC=C(C=C1)C2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BJ6W4D	4-(4-Methoxyphenyl)-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide	Investigative	3649035	C18H22N2O3S	346.4	COC1=CC=C(C=C1)C2=CSC(=C2)C(=O)NCCN3CCOCC3	IC50 ~ 101000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BJI49R	Chembl4202455	Investigative	145977231	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BJK4U1	Chembl4202528	Investigative	145976230	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BJWP32	1-Phenyl-3-(5-sulfanyl-1,3,4-thiadiazol-2-yl)urea	Investigative	10658473	C9H8N4OS2	252.3	C1=CC=C(C=C1)NC(=O)NC2=NNC(=S)S2	IC50 = 99000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BK12BZ	(5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136814721	C17H11N3O2S2	353.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C\\C4=CC(=CC=C4)O)/S3	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BK16HW	(Sec-butylamino)carbonylphosphonic acid	Investigative	11286824	C5H12NO4P	181.13	CCC(C)NC(=O)P(=O)(O)O	IC50 = 80000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BK5G4F	(5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(2-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136814723	C17H11N3O2S2	353.4	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	IC50 = 97350 nM	Poor binder
T86702	Matrix metalloproteinase-3	BKM8G4	2-[(4'-Fluorobiphenyl-4-yl)sulfonyl]benzeneacetic acid	Investigative	71602248	C20H15FO4S	370.4	C1=CC=C(C(=C1)CC(=O)O)S(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)F	IC50 = 67000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BLF1I4	Chembl4207344	Investigative	145975699	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BMC9X6	4-{(5Z)-2,4-Dioxo-5-[(2E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl}butanoic acid	Investigative	1348435	C16H15NO4S	317.4	C1=CC=C(C=C1)/C=C/C=C\\2/C(=O)N(C(=O)S2)CCCC(=O)O	IC50 = 110000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BNJ04P	5-(Phenylamino)-1,3,4-thiadiazole-2(3H)-thione	Investigative	707055	C8H7N3S2	209.3	C1=CC=C(C=C1)NC2=NNC(=S)S2	IC50 = 190000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BO9J4I	(2S)-2-[[(2R)-2-Amino-3-methylbutanoyl]amino]-N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	44356789	C27H38N4O3	466.6	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)[C@@H](C(C)C)N	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BOL2C9	N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide	Investigative	10610500	C6H9N5O2S2	247.3	CNC(=O)CNC(=O)NC1=NNC(=S)S1	Ki = 165958.69 nM	Poor binder
T86702	Matrix metalloproteinase-3	BP50JB	Antibiotic A 26771B	Investigative	11143436	C20H30O7	382.4	C[C@@H]1CCCCCCCCC[C@@H](C(=O)/C=C/C(=O)O1)OC(=O)CCC(=O)O	IC50 = 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BP6ED9	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-[(3-nitrophenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	136036777	C17H10N4O3S2	382.4	C1=CC=C2C(=C1)C(=NS2)N=C3NC(=O)/C(=C/C4=CC(=CC=C4)[N+](=O)[O-])/S3	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BP6NW4	(Cyclobutylamino)carbonylphosphonic acid	Investigative	11194666	C5H10NO4P	179.11	C1CC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BQ07HA	(2s)-6-[(4-Fluorobenzyl)amino]-2-[(2r)-2-(4-Fluorophenyl)-2-Methoxyethyl]-N-Hydroxyhexanamide	Investigative	54582019	C22H28F2N2O3	406.5	CO[C@H](C[C@H](CCCCNCC1=CC=C(C=C1)F)C(=O)NO)C2=CC=C(C=C2)F	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BQ9P2T	5-(Benzylamino)-1,3,4-thiadiazole-2-thiol	Investigative	830422	C9H9N3S2	223.3	C1=CC=C(C=C1)CNC2=NNC(=S)S2	IC50 = 97000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BQK86U	1-(4-Chloro-2-methyl-phenyl)-3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-urea	Investigative	44285342	C10H9ClN4OS2	300.8	CC1=C(C=CC(=C1)Cl)NC(=O)NC2=NNC(=S)S2	Ki = 119000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BQRJ21	(2S,4R)-4-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-2-methyl-6-phenyl-hexanoic acid	Investigative	44294877	C25H32N2O5	440.5	C[C@@H](C[C@@H](CCC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OC)C(=O)NC)C(=O)O	IC50 = 55000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BRD5Z7	(2r,3r)-4-[4-(2-Chlorophenyl)piperazin-1-Yl]-2,3-Dihydroxy-4-Oxo-N-(2-Thiophen-2-Ylethyl)butanamide	Investigative	11640694	C20H24ClN3O4S	437.9	C1CN(CCN1C2=CC=CC=C2Cl)C(=O)[C@@H]([C@H](C(=O)NCCC3=CC=CS3)O)O	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BS2M5I	(5Z)-2-(1,2-Benzothiazol-3-ylimino)-5-benzylidene-1,3-thiazolidin-4-one	Investigative	136036787	C17H11N3OS2	337.4	C1=CC=C(C=C1)/C=C\\2/C(=O)NC(=NC3=NSC4=CC=CC=C43)S2	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BS4KA8	Chembl4206956	Investigative	145975682	C33H24O4	484.5	C1=CC=C(C=C1)/C(=C\\C(=O)C2=CC=C(C=C2)O)/C3=C(C=CC=C3C4=CC=C(C=C4)O)C5=CC=C(C=C5)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BSK02N	2-(5-(4-(Benzyloxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid	Investigative	1383990	C19H15NO4S2	385.5	C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C\\3/C(=O)N(C(=S)S3)CC(=O)O	IC50 = 58500 nM	Poor binder
T86702	Matrix metalloproteinase-3	BSP3A8	Schembl22225166	Investigative	17853548	C17H20O9	368.3	COC(=O)C1(CC(C(C(C1)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O)O	IC50 = 58810 nM	Poor binder
T86702	Matrix metalloproteinase-3	BSRZ86	Cyclopentylcarbamoylphosphonic Acid	Investigative	10198038	C6H12NO4P	193.14	C1CCC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BT17QX	Lithium ethyl (cyclohexylamino)carbonylphosphonate	Investigative	53322469	C9H17LiNO4P	241.2	[Li+].CCOP(=O)(C(=O)NC1CCCCC1)[O-]	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BTE3R6	(2E)-3-(N-Hydroxycarbamoyl)-2-heptylidenepropionyl-L-tryptophan-N-methylamide	Investigative	44434565	C23H32N4O4	428.5	CCCCCC/C=C(\\CC(=O)NO)/C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BU72GZ	N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride	Investigative	71680867	C22H30ClN3O5S	484	C1[C@@H]([C@H](CN1C(=O)CCCCCN)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BV0CJ9	4-Phenoxy-N-[(1R,2R)-2-sulfanylcyclopentyl]benzenesulfonamide	Investigative	71682916	C17H19NO3S2	349.5	C1C[C@H]([C@@H](C1)S)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BVAB51	Chembl4214656	Investigative	145972990	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BVQ1A0	Z-D-Trp-OH	Investigative	700663	C19H18N2O4	338.4	C1=CC=C(C=C1)COC(=O)N[C@H](CC2=CNC3=CC=CC=C32)C(=O)O	Ki = 71000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BVZ90P	(Isopropylamino)carbonylphosphonic acid	Investigative	11147931	C4H10NO4P	167.1	CC(C)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BW31OG	(Ethylamino)carbonylphosphonic acid	Investigative	11205873	C3H8NO4P	153.07	CCNC(=O)P(=O)(O)O	IC50 = 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BX1NG5	Phenethylcarbamoylphosphonic Acid	Investigative	9794947	C9H12NO4P	229.17	C1=CC=C(C=C1)CCNC(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BX35SB	Chembl4207416	Investigative	145978615	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)F	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BX9N5F	[3-(5-Thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetic acid ethyl ester	Investigative	44285516	C7H10N4O3S2	262.3	CCOC(=O)CNC(=O)NC1=NNC(=S)S1	Ki = 85000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BXW5Y2	Pentan-3-ylcarbamoylphosphonic Acid	Investigative	11367571	C6H14NO4P	195.15	CCC(CC)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 = 91000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BY8QH0	Piperidin-1-ylcarbonylphosphonic acid	Investigative	44328155	C6H12NO4P	193.14	C1CCN(CC1)C(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BYSM39	(+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic Acid	Investigative	44479702	C21H18O4S	366.4	CC(C1=CC=CC=C1S(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	BZSF06	N-{2-[(4'-Cyano-1,1'-biphenyl-4-YL)oxy]ethyl}-N'-hydroxy-N-methylurea	Investigative	5326979	C17H17N3O3	311.33	CN(CCOC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)C(=O)NO	IC50 = 200000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D01BCK	N-hydroxy-1-naphthamide	Investigative	23382	C11H9NO2	187.19	C1=CC=C2C(=C1)C=CC=C2C(=O)NO	IC50 = 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D07MJD	[2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid	Investigative	44479701	C20H16O4S	352.4	C1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3CC(=O)O	IC50 = 74000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D0A0FY	N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide	Investigative	44479457	C14H13NO5S	307.32	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2C(=O)NO	IC50 ~ 50000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D0G3YZ	(+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid	Investigative	11391583	C17H18O3	270.32	C1=CC=C(C=C1)C2=CC=C(C=C2)CCC(CC(=O)O)O	IC50 ~ 98000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D0N8YA	Bb-3497	Investigative	159596	C16H31N3O4	329.43	CCCC[C@H](CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T86702	Matrix metalloproteinase-3	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder