TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T87020	FK506-binding protein 4	D04PGB	Gpi-1046	Terminated	445501	C20H28N2O4	360.4	CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)OCCCC2=CN=CC=C2	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B0L7AP	2-[3-[(1R)-1-[(2S)-1-[(2S)-2-Cyclohexyl-2-(3-methoxyphenyl)acetyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	122192628	C40H49NO9	687.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3C(=O)[C@@H](C4CCCCC4)C5=CC(=CC=C5)OC)OC	Ki ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B1YN9J	2-[3-[(1R)-1-[(2S)-1-(1-Benzothiophen-2-ylsulfonyl)piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522007	C33H35NO9S2	653.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=CC=CC=C5S4)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B27XKZ	CID 57522008	Investigative	57522008	C32H34N2O9S	622.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=CC(=C4)C#N)OC	IC50 = 69900 nM	Poor binder
T87020	FK506-binding protein 4	B29GBH	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,5-dichlorophenyl)sulfonylpiperidine-2-carboxylate	Investigative	57522800	C22H25Cl2NO7S	518.4	COC1=C(C=C(C=C1)OCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)C3=CC(=CC(=C3)Cl)Cl)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B2O6HW	2-[3-[(1R)-1-[(2S)-1-(3,4-Dichlorophenyl)sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522240	C31H33Cl2NO9S	666.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C=C4)Cl)Cl)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B34IZK	2-[3-[3-(3,4-Dimethoxyphenyl)-1-[[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl]amino]propyl]phenoxy]acetic acid	Investigative	70684253	C32H42N2O8	582.7	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)NC(CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B3KMZ1	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(3R)-4-(3,3-dimethyl-2-oxopentanoyl)thiomorpholine-3-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	57523064	C31H39NO9S	601.7	CCC(C)(C)C(=O)C(=O)N1CCSC[C@H]1C(=O)O[C@H](CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B40KDB	CID 57522683	Investigative	57522683	C32H34N2O10S2	670.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)S5)OC	IC50 = 66500 nM	Poor binder
T87020	FK506-binding protein 4	B41QWJ	CID 57522347	Investigative	57522347	C33H39NO11S	657.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B4LOY0	CID 57522570	Investigative	57522570	C33H38N2O10S	654.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C(=C4)N)OCC5)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B5XB8K	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-pyrimidin-4-ylsulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	70694726	C29H33N3O9S	599.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=NC=NC=C4)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B6Z0BU	Timcodar	Investigative	9811664	C43H45ClN4O6	749.3	CN([C@@H](CC1=CC=C(C=C1)Cl)C(=O)N(CC2=CC=CC=C2)C(CCC3=CC=NC=C3)CCC4=CC=NC=C4)C(=O)C(=O)C5=CC(=C(C(=C5)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B7QX2W	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(1,3-benzothiazol-6-ylsulfonyl)piperidine-2-carboxylate	Investigative	57522801	C23H26N2O7S2	506.6	COC1=C(C=C(C=C1)OCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)C3=CC4=C(C=C3)N=CS4)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	B8P2GI	2-[3-[(1R)-1-[(2S)-1-[(2S)-2-Cyclohexyl-2-(3,5-dimethoxyphenyl)acetyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	122192627	C41H51NO10	717.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3C(=O)[C@@H](C4CCCCC4)C5=CC(=CC(=C5)OC)OC)OC	Ki ~ 50000 nM	Poor binder
T87020	FK506-binding protein 4	B9S4OK	CID 57522685	Investigative	57522685	C32H34N2O11S	654.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)O5)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BA1IR3	(S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester	Investigative	9820942	C21H30N2O4	374.5	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCCCC2=CN=CC=C2	IC50 ~ 150000 nM	Poor binder
T87020	FK506-binding protein 4	BA2M3B	CID 57521881	Investigative	57521881	C35H37N3O9S	675.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=C(C=C4)C5=NC=CC=N5)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BAU81E	CID 57522684	Investigative	57522684	C33H36N2O10S	652.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)C5)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BB34GP	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate	Investigative	57521460	C23H33NO7	435.5	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCCOC2=CC(=C(C=C2)OC)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BCB94E	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-[2-[(1S,2R)-2-ethyl-1-hydroxycyclohexyl]-2-oxoacetyl]piperidine-2-carboxylate	Investigative	70694756	C26H37NO8	491.6	CC[C@@H]1CCCC[C@]1(C(=O)C(=O)N2CCCC[C@H]2C(=O)OCCOC3=CC(=C(C=C3)OC)OC)O	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BCJ03A	2-[3-[(1R)-1-[(2S)-1-[3,5-Bis(methoxycarbonyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522456	C35H39NO13S	713.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)C(=O)OC)C(=O)OC)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BDM43O	CID 57522121	Investigative	57522121	C31H36N2O9S	612.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=CC(=C4)N)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BE1I0W	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-(2-methylpyrimidin-4-yl)sulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	70694725	C30H35N3O9S	613.7	CC1=NC=CC(=N1)S(=O)(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BGE20P	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-(3-nitrophenyl)sulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	57522120	C31H34N2O11S	642.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=CC(=C4)[N+](=O)[O-])OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BJ04FY	CID 57522237	Investigative	57522237	C31H34FNO9S	615.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=CC(=C4)F)OC	IC50 = 84500 nM	Poor binder
T87020	FK506-binding protein 4	BK0E3Y	2-[3-[(1R)-1-[(2S)-1-[3,5-Bis(trifluoromethyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522350	C33H33F6NO9S	733.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BKO21J	2-[3-[(1R)-1-[(2S)-1-[3-Bromo-5-(trifluoromethyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522455	C32H33BrF3NO9S	744.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)C(F)(F)F)Br)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BL19CE	2-[3-[(1R)-1-[[(2S)-1-(3,5-Dichloro-4-hydroxyphenyl)sulfonylpiperidine-2-carbonyl]amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57523068	C31H34Cl2N2O9S	681.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)NC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C(=C4)Cl)O)Cl)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BLP6S7	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[[(2S)-1-[(2-oxo-3H-1,3-benzothiazol-6-yl)sulfonyl]piperidine-2-carbonyl]amino]propyl]phenoxy]acetic acid	Investigative	57523069	C32H35N3O9S2	669.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)NC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)S5)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BO8R1Z	CID 57522929	Investigative	57522929	C36H44Cl2N2O9S	751.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC(=C(C(=C5)Cl)OC)Cl)OC	IC50 ~ 50000 nM	Poor binder
T87020	FK506-binding protein 4	BRY4H6	(21S)-1Aza-4,4-dimethyl-6,19-dioxa-2,3,7,20-tetraoxobicyclo[19.4.0] pentacosane	Investigative	445646	C24H39NO6	437.6	CC1(COC(=O)CCCCCCCCCCCOC(=O)[C@@H]2CCCCN2C(=O)C1=O)C	Ki = 100000 nM	Poor binder
T87020	FK506-binding protein 4	BTKO61	CID 57522803	Investigative	57522803	C36H43N3O8S2	709.9	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC6=C(C=C5)N=CS6)OC	IC50 ~ 50000 nM	Poor binder
T87020	FK506-binding protein 4	BU1CW6	CID 57522006	Investigative	57522006	C29H33NO10S	587.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=COC=C4)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BVTW76	4,4-Dimethyl-6,17-dioxa-1-azabicyclo[17.4.0]tricosane-2,3,7,18-tetrone	Investigative	9822783	C22H35NO6	409.5	CC1(COC(=O)CCCCCCCCCOC(=O)C2CCCCN2C(=O)C1=O)C	Ki = 90000 nM	Poor binder
T87020	FK506-binding protein 4	BX21PC	18-(2-Cyclohexylethyl)-4,4-dimethyl-6,19-dioxa-1-azabicyclo[19.4.0]pentacosane-2,3,7,20-tetrone	Investigative	44339314	C32H53NO6	547.8	CC1(COC(=O)CCCCCCCCCCC(OC(=O)C2CCCCN2C(=O)C1=O)CCC3CCCCC3)C	Ki = 190000 nM	Poor binder
T87020	FK506-binding protein 4	BX8Z3L	Methyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate	Investigative	11129344	C14H23NO4	269.34	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OC	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BXYE40	2-(3,4-Dimethoxyphenyl)ethyl (2S)-1-[2-[(1S,2R)-1-hydroxy-2-methylcyclohexyl]-2-oxoacetyl]piperidine-2-carboxylate	Investigative	70688508	C25H35NO7	461.5	C[C@@H]1CCCC[C@]1(C(=O)C(=O)N2CCCC[C@H]2C(=O)OCCC3=CC(=C(C=C3)OC)OC)O	IC50 ~ 100000 nM	Poor binder
T87020	FK506-binding protein 4	BYW1B3	SAFit1	Investigative	86277875	C42H53NO11	747.9	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3C(=O)[C@@H](C4CCCCC4)C5=CC(=C(C(=C5)OC)OC)OC)OC	Ki ~ 50000 nM	Poor binder
T87020	FK506-binding protein 4	BZTN10	CID 57522802	Investigative	57522802	C35H42Cl2N2O8S	721.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC(=CC(=C5)Cl)Cl)OC	IC50 ~ 50000 nM	Poor binder