TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T89918	Glycinamide ribonucleotide formyltransferase	B87QHO	1,5-Dihydroimidazo[4,5-C][1,2,6]thiadiazin-4(3h)-One 2,2-Dioxide	Investigative	12413165	C4H4N4O3S	188.17	C1=NC2=C(N1)C(=O)NS(=O)(=O)N2	Ki ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BH6TX1	2-[[4-[[(2-Amino-4-oxo-3H-pyrido[2,3-d]pyrimidin-6-yl)-formylamino]methyl]benzoyl]amino]pentanedioic acid	Investigative	135887128	C21H20N6O7	468.4	C1=CC(=CC=C1CN(C=O)C2=CC3=C(N=C2)N=C(NC3=O)N)C(=O)NC(CCC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BHM71S	2-[[4-[[(2-Amino-4-oxo-3H-pyrido[2,3-d]pyrimidin-6-yl)amino]methyl]benzoyl]amino]pentanedioic acid	Investigative	135887126	C20H20N6O6	440.4	C1=CC(=CC=C1CNC2=CC3=C(N=C2)N=C(NC3=O)N)C(=O)NC(CCC(=O)O)C(=O)O	IC50 = 85900 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BN7GV4	7-(3,4-Dihydroxy-5r-Hydroxymethyltetrahydrofuran-2-Yl)-2,2-Dioxo-1,2r,3r,7-Tetrahydro-2l6-Imidazo[4,5-C][1,2,6]thiadiazin-4s-One	Investigative	11963491	C9H12N4O7S	320.28	C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)NS(=O)(=O)NC2=O	Ki ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BOT31S	2-{4-[3-(4-Amino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propylamino]-benzoylamino}-pentanedioic acid	Investigative	136002156	C19H23N5O6	417.4	C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCCCC2=C(N=CNC2=O)N	IC50 = 52000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BVW20J	2-{4-[3-(3-Amino-5-oxo-2,5-dihydro-[1,2,4]triazin-6-yl)-2-oxo-pyrrolidin-1-yl]-benzoylamino}-pentanedioic acid	Investigative	135881773	C19H20N6O7	444.4	C1CN(C(=O)C1C2=NN=C(NC2=O)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BW8ZJ2	2-[[4-[[(2-Amino-4-oxo-3H-pyrido[2,3-d]pyrimidin-6-yl)-methylamino]methyl]benzoyl]amino]pentanedioic acid	Investigative	135887127	C21H22N6O6	454.4	CN(CC1=CC=C(C=C1)C(=O)NC(CCC(=O)O)C(=O)O)C2=CC3=C(N=C2)N=C(NC3=O)N	IC50 ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BX2WQ5	(S)-2-{4-[2-(4-Oxo-3,4,5,6,7,8-hexahydro-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid	Investigative	136026553	C21H24N4O6	428.4	C1C(CNC2=C1C(=O)NC=N2)CCC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O	Ki = 82100 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BYH6P4	2,6-Diamino-5-[6-(1,3-benzoxazol-2-yl)-6-oxohexyl]pyrimidin-4(1H)-one	Investigative	136152909	C17H19N5O3	341.4	C1=CC=C2C(=C1)N=C(O2)C(=O)CCCCCC3=C(N=C(NC3=O)N)N	Ki ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BYRJ16	2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-(4-fluoro-3-nitro-benzyl)-amino]-benzoylamino}-pentanedioic acid	Investigative	136002209	C28H25FN6O8	592.5	C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)N(CC2=CC3=C(C=C2)N=C(NC3=O)N)CC4=CC(=C(C=C4)F)[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T89918	Glycinamide ribonucleotide formyltransferase	BZHD98	(2S)-2-[[4-[2-(2-Amino-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl)ethyl]benzoyl]amino]pentanedioic acid	Investigative	9910387; 91934698	C21H25N5O5	427.5	C1C(CNC2=NC(=NC=C21)N)CCC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O	Ki = 186000 nM	Poor binder