TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T90985 Bromodomain testis-specific protein B0NZ2X 8-[[(3R,4R)-3-[(1,1-Dioxothian-4-yl)methoxy]piperidin-4-yl]amino]-3-methyl-5-(5-methylpyridin-3-yl)-1H-1,7-naphthyridin-2-one Investigative 122181550 C26H33N5O4S 511.6 CC1=CC(=CN=C1)C2=CN=C(C3=C2C=C(C(=O)N3)C)N[C@@H]4CCNC[C@H]4OCC5CCS(=O)(=O)CC5 IC50 ~ 50118.72 nM Poor binder T90985 Bromodomain testis-specific protein B37FTW Chembl4207347 Investigative 145975701 C30H43N7O4 565.7 CC(C)C[C@@H]1C(=O)N(C2=CN=C(N=C2N1C3CCOCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C IC50 ~ 50000 nM Poor binder T90985 Bromodomain testis-specific protein B4MX5P 3-Butyl-8-[(6-Butyl-5,7-Dimethyl-[1,2,4]triazolo[1,5-A]pyrimidin-2-Yl)sulfanylmethyl]-7-Ethyl-Purine-2,6-Dione Investigative 60498769 C23H32N8O2S 484.6 CCCCC1=C(N2C(=NC(=N2)SCC3=NC4=C(N3CC)C(=O)NC(=O)N4CCCC)N=C1C)C IC50 = 100000 nM Poor binder T90985 Bromodomain testis-specific protein B4RST8 8-(2-Hydroxyethylamino)-7-(naphthalen-1-ylmethyl)-3H-purine-2,6-dione Investigative 137661484 C18H17N5O3 351.4 C1=CC=C2C(=C1)C=CC=C2CN3C4=C(NC(=O)NC4=O)N=C3NCCO IC50 = 87000 nM Poor binder T90985 Bromodomain testis-specific protein B6BLR2 8-[(5-Amino-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-3-[(4-chlorophenyl)methyl]-7-ethylpurine-2,6-dione Investigative 127033568 C17H17ClN8O2S 432.9 CCN1C(=NC2=C1C(=O)NC(=O)N2CC3=CC=C(C=C3)Cl)CSC4=NNC(=N4)N IC50 ~ 100000 nM Poor binder T90985 Bromodomain testis-specific protein B7SF9U 4-(2,5-Dimethoxyphenyl)-3-methyl-5-propyl-2,4-dihydropyrrolo[3,4-c]pyrrol-6-one Investigative 137633398 C18H22N2O3 314.4 CCCN1C(C2=C(NC=C2C1=O)C)C3=C(C=CC(=C3)OC)OC IC50 = 67000 nM Poor binder T90985 Bromodomain testis-specific protein B9IUR3 1,3-Diethyl-2-oxo-2,3-dihydro-1H-benzoimidazole-5-carbaldehyde Investigative 6484105 C12H14N2O2 218.25 CCN1C2=C(C=C(C=C2)C=O)N(C1=O)CC IC50 = 140000 nM Poor binder T90985 Bromodomain testis-specific protein BF83PN 5-(2-Furyl)-1-(tetrahydro-2-furanylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Investigative 16414715 C16H15N3O4 313.31 C1CC(OC1)CN2C3=NC=CC(=C3C(=O)NC2=O)C4=CC=CO4 IC50 = 130000 nM Poor binder T90985 Bromodomain testis-specific protein BH1NI5 2-(4-Hydroxy-3,5-Dimethylphenyl)-7-Methyl-5,6,7,8-Tetrahydropyrido[4',3':4,5]thieno[2,3-D]pyrimidin-4(3h)-One Investigative 135567026 C18H19N3O2S 341.4 CC1=CC(=CC(=C1O)C)C2=NC3=C(C4=C(S3)CN(CC4)C)C(=O)N2 IC50 ~ 100000 nM Poor binder T90985 Bromodomain testis-specific protein BJM25E (E)-N'-Methoxy-N-[7-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methanimidamide Investigative 9581822 C12H11N7O 269.26 CON/C=N/C1=NN2C(=CC=NC2=N1)C3=CN=CC=C3 IC50 = 120000 nM Poor binder T90985 Bromodomain testis-specific protein BYIO03 7-(4-Fluorobenzyl)-3-methyl-8-(methylamino)-1H-purine-2,6(3H,7H)-dione Investigative 719444 C14H14FN5O2 303.29 CNC1=NC2=C(N1CC3=CC=C(C=C3)F)C(=O)NC(=O)N2C IC50 = 68000 nM Poor binder