TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T91331 Fibroblast growth factor receptor 3 B2Z6TE Chembl4162722 Investigative 145957742 C13H9FN2O 228.22 C1=CC2=C(C=C1C3=C(C=C(C=C3)O)F)NN=C2 IC50 ~ 100000 nM Poor binder T91331 Fibroblast growth factor receptor 3 B4P9VK [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-[6-[3-(trifluoromethyl)phenyl]-1H-indol-2-yl]methanone Investigative 50939485 C27H19F3N6O 500.5 CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=C(N4)C=C(C=C5)C6=CC(=CC=C6)C(F)(F)F)N IC50 = 50000 nM Poor binder T91331 Fibroblast growth factor receptor 3 B58USB Chembl4173432 Investigative 145950580 C15H12F2N2O 274.26 CCOC1=C(C(=C(C=C1)F)C2=CC3=C(C=C2)C=NN3)F IC50 ~ 100000 nM Poor binder T91331 Fibroblast growth factor receptor 3 BE5D7B 5-[5-Amino-4-(1H-indole-2-carbonyl)pyrazol-1-yl]-1,3-dihydrobenzimidazol-2-one Investigative 134144799 C19H14N6O2 358.4 C1=CC=C2C(=C1)C=C(N2)C(=O)C3=C(N(N=C3)C4=CC5=C(C=C4)NC(=O)N5)N IC50 ~ 50000 nM Poor binder T91331 Fibroblast growth factor receptor 3 BF6K7D Chembl4163123 Investigative 145958261 C15H13FN2O 256.269 CCOC1=CC(=CC(=C1)C2=CC3=C(C=C2)C=NN3)F IC50 ~ 100000 nM Poor binder T91331 Fibroblast growth factor receptor 3 BM5DZ4 OC1=CC=C(C=C1)C1=CC=C2C=Nnc2=C1 Investigative 136301774 C13H10N2O 210.23 C1=CC(=CC=C1C2=CC3=C(C=C2)C=NN3)O IC50 = 51000 nM Poor binder T91331 Fibroblast growth factor receptor 3 BVS5I8 Chembl4171043 Investigative 145949598 C15H13FN2O 256.269 CCOC1=CC=CC(=C1F)C2=CC3=C(C=C2)C=NN3 IC50 ~ 100000 nM Poor binder