TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92777	Intestinal maltase-glucoamylase	B0H2LP	5-Butylidene-3-(2-((1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-decahydronaphthalen-1-yl)vinyl)furan-2(5H)-one	Investigative	44411124	C24H34O4	386.5	CCC/C=C\\1/C=C(C(=O)O1)/C=C/[C@@H]2C(=C)CC[C@H]3[C@]2(CC[C@H]([C@@]3(C)CO)O)C	IC50 = 110000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B2COX1	[(2R,3R,4R,5R,6S)-1-[(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-2,4,5,6,7-pentahydroxyheptan-3-yl] hydrogen sulfate	Investigative	44514062; 52946778	C12H25NO12S	407.39	C1[C@H]([C@@H]([C@H](N1C[C@H]([C@H]([C@@H]([C@@H]([C@H](CO)O)O)O)OS(=O)(=O)O)O)CO)O)O	Ki = 90000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B2HKB1	(2R,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118411077	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@H](N1CC(CCCOCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B2O6HK	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(4-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411070	C24H33NO5	415.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC=C(C=C2)C3=CC=CC=C3)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B3VHO8	4-(1,3-Benzothiazol-2-yl)-N-[(E)-(4-hydroxy-3-methoxyphenyl)methylideneamino]benzamide	Investigative	136961473	C22H17N3O3S	403.5	COC1=C(C=CC(=C1)/C=N/NC(=O)C2=CC=C(C=C2)C3=NC4=CC=CC=C4S3)O	IC50 = 53340 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B4FQ0M	14-Deoxy-15-(p-(dimethanylamino)-benzylidene)-11,12-didehydroandrographolide	Investigative	44437483	C29H37NO4	463.6	C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2/C=C/C3=C/C(=C/C4=CC=C(C=C4)N(C)C)/OC3=O)(C)CO)O	IC50 = 70000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B4NZ6J	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(3-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118720306	C24H33NO5	415.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC(=CC=C2)C3=CC=CC=C3)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B54YTP	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triol	Investigative	118720304	C25H35NO5	429.5	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2)OCCCCCN3C[C@@H]([C@H]([C@@H]([C@@H]3CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B57RNF	15-Benzylidene-14-deoxy-11,12-didehydroandrographolide	Investigative	16121613	C27H32O4	420.5	C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2/C=C/C3=C/C(=C/C4=CC=CC=C4)/OC3=O)(C)CO)O	IC50 = 58000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B6PL7N	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1R)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triol	Investigative	118720305	C25H35NO5	429.5	C[C@H](C1=CC=C(C=C1)C2=CC=CC=C2)OCCCCCN3C[C@@H]([C@H]([C@@H]([C@@H]3CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B6Q4EG	(2R,3R,5R,6R)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triol	Investigative	195553	C7H15NO5	193.2	C([C@@H]1[C@H](C([C@@H]([C@H](N1)CO)O)O)O)O	IC50 = 110000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B7N5OH	(2S,3R,4R,5S)-1-[5-[(2-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118411069	C24H32FNO5	433.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=C(C=C(C=C2)C3=CC=CC=C3)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B9CJE2	(5Z)-3-[(E)-2-[(1S,2S,4As,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]ethenyl]-5-[(E)-3-phenylprop-2-enylidene]furan-2-one	Investigative	44411115	C29H34O5	462.6	C[C@@]12CC[C@H]([C@@]([C@H]1CC[C@]3([C@H]2/C=C/C4=C/C(=C/C=C/C5=CC=CC=C5)/OC4=O)CO3)(C)CO)O	IC50 = 101000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	B9T2LZ	(1R,3S,6R)-6-Hexylamino-4-hydroxymethyl-cyclohex-4-ene-1,2,3-triol	Investigative	44384057	C13H25NO4	259.339	CCCCCCNC1C=C(C(C(C1O)O)O)CO	IC50 = 50000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BB1AK0	(S)-3-(2-((4Ar,6aS,7R,10aS,10bR)-3-(3-bromophenyl)-6a,10b-dimethyl-8-methylene-decahydro-1H-naphtho[2,1-d][1,3]dioxin-7-yl)ethylidene)-4-hydroxy-dihydrofuran-2(3H)-one	Investigative	44411113	C27H33BrO5	517.5	C[C@@]12CC[C@@H]3[C@]([C@H]1CCC(=C)[C@H]2C/C=C/4\\[C@@H](COC4=O)O)(COC(O3)C5=CC(=CC=C5)Br)C	IC50 = 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BCI2W8	14-Deoxy-11,12-didehydro-15-(-2-furanmethanylidene)-andrographolide	Investigative	44437486	C25H30O5	410.5	C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2/C=C/C3=C/C(=C/C4=CC=CO4)/OC3=O)(C)CO)O	IC50 = 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BDZ60T	(2S,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118720307	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CC(CCCOCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BF5T7N	(1S,2S,3R,6S)-6-[[(2R,3R,4S,5R,6S)-4,5-Dihydroxy-6-methoxy-2-methyloxan-3-yl]amino]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol	Investigative	70690487	C14H25NO8	335.35	C[C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)OC)O)O)N[C@H]2C=C([C@H]([C@@H]([C@H]2O)O)O)CO	IC50 = 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BGT3W5	14-Deoxy-11,12-didehydro-15-trimethoxylbenzylideneandrographolide	Investigative	44437482	C30H38O7	510.6	C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2/C=C/C3=C/C(=C/C4=CC(=C(C=C4OC)OC)OC)/OC3=O)(C)CO)O	IC50 = 84000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BJR1F3	(5Z)-3-[(E)-2-[(1S,2S,4As,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]ethenyl]-5-[(4-methoxyphenyl)methylidene]furan-2-one	Investigative	44411114	C28H34O6	466.6	C[C@@]12CC[C@H]([C@@]([C@H]1CC[C@]3([C@H]2/C=C/C4=C/C(=C/C5=CC=C(C=C5)OC)/OC4=O)CO3)(C)CO)O	IC50 = 120000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BL6IZ4	15-(Benzo[1,3]dioxole-5-methanylidene)-14-deoxy-11,12-didehydroandrographolide	Investigative	16121614	C28H32O6	464.5	C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2/C=C/C3=C/C(=C/C4=CC5=C(C=C4)OCO5)/OC3=O)(C)CO)O	IC50 = 82000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BLE9A0	3-(2-((1R,4As,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-decahydronaphthalen-1-yl)vinyl)-5-(3-phenylallylidene)furan-2(5H)-one	Investigative	44411422	C29H34O4	446.6	C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2/C=C/C3=C/C(=C/C=C/C4=CC=CC=C4)/OC3=O)(C)CO)O	IC50 = 58000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BM60EO	(2S)-1-[5-(2-Fluoro-1,1'-biphenyl-4-ylmethoxy)pentyl]-2beta-(hydroxymethyl)piperidine-3beta,4alpha,5beta-triol	Investigative	101882900	C24H32FNO5	433.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC(=C(C=C2)C3=CC=CC=C3)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BMH25Y	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(2-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411153	C24H33NO5	415.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC=CC=C2C3=CC=CC=C3)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BNFR84	(2S,3R,4R,5S)-1-[4,4-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118720308	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCC(COCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BS57LD	Valienamine	Investigative	193758	C7H13NO4	175.18	C1=C([C@H]([C@@H]([C@H]([C@H]1N)O)O)O)CO	IC50 = 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BU4R8D	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411149	C25H32F3NO5	483.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BV9FR4	Validamine	Investigative	446685	C7H15NO4	177.2	C1[C@@H]([C@H]([C@@H]([C@H]([C@H]1N)O)O)O)CO	IC50 = 110000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BWZ3K1	(1S,2S,3R,6S)-6-[[(2S,3R,4S,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]amino]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol	Investigative	70692640	C14H25NO9	351.35	CO[C@@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)N[C@H]2C=C([C@H]([C@@H]([C@H]2O)O)O)CO)O)O	IC50 = 80000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BXU1E0	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triol	Investigative	118411108	C25H32F3NO5	483.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=C(C=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CO)O)O)O	IC50 ~ 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BY63XA	(5S,8R,9S,10S,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one;(8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one	Investigative	54584900	C38H60O4	580.9	C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4[C@@]3(CCC(=O)C4)C	IC50 = 100000 nM	Poor binder
T92777	Intestinal maltase-glucoamylase	BY7H9M	(S)-3-(2-((4Ar,6aS,7R,10aS,10bR)-6a,10b-dimethyl-8-methylene-3-phenyl-decahydro-1H-naphtho[2,1-d][1,3]dioxin-7-yl)ethylidene)-4-hydroxy-dihydrofuran-2(3H)-one	Investigative	44411131	C27H34O5	438.6	C[C@@]12CC[C@@H]3[C@]([C@H]1CCC(=C)[C@H]2C/C=C/4\\[C@@H](COC4=O)O)(COC(O3)C5=CC=CC=C5)C	IC50 = 101000 nM	Poor binder