TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T93105	Presenilin 1	B49OBL	Methyl 2-[[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl]oxy]acetate	Investigative	20632905	C32H54O4	502.8	CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OCC(=O)OC)C	IC50 ~ 100000 nM	Poor binder
T93105	Presenilin 1	B56OLS	2-[6-Chloro-9-[(E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl]carbazol-2-yl]propanoic acid	Investigative	71682359	C35H50ClNO2	552.2	C[C@@H](CCC[C@@H](C)CCC/C(=C/CN1C2=C(C=C(C=C2)Cl)C3=C1C=C(C=C3)C(C)C(=O)O)/C)CCCC(C)C	EC50 ~ 50000 nM	Poor binder
T93105	Presenilin 1	B8IB4M	2,5,7,8-Tetramethyl-6-octoxy-3,4-dihydrochromene-2-carboxylic acid	Investigative	71682361	C22H34O4	362.5	CCCCCCCCOC1=C(C2=C(C(=C1C)C)OC(CC2)(C)C(=O)O)C	EC50 ~ 50000 nM	Poor binder
T93105	Presenilin 1	BQE56W	2,5,7,8-Tetramethyl-6-undecoxy-3,4-dihydrochromene-2-carboxylic acid	Investigative	71682362	C25H40O4	404.6	CCCCCCCCCCCOC1=C(C2=C(C(=C1C)C)OC(CC2)(C)C(=O)O)C	IC50 ~ 50000 nM	Poor binder
T93105	Presenilin 1	BQY5O1	DL-alpha-Tocopherol	Investigative	2116	C29H50O2	430.7	CC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C	EC50 ~ 100000 nM	Poor binder