TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T93716	Kinesin heavy chain neuron-specific 1	D0V2YJ	MK-0731	Phase 1	11655511	C25H28F3N3O2	459.5	CN1CC[C@@H]([C@@H](C1)F)N(C)C(=O)N2CC(=C[C@@]2(CO)C3=CC=CC=C3)C4=C(C=CC(=C4)F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B05COY	2-((4-(Methylthio)phenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45267853	C23H19F3N4OS	456.5	CSC1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B0AUW4	2-(2,4-Difluorophenyl)-9-(3,4-dimethylphenyl)-8-oxo-7H-purine-6-carboxamide	Investigative	22577556	C20H15F2N5O2	395.4	CC1=C(C=C(C=C1)N2C3=NC(=NC(=C3NC2=O)C(=O)N)C4=C(C=C(C=C4)F)F)C	IC50 = 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B10LOM	1-(1-Phenylcyclopropyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45272180	C23H21N5O3S	447.5	C1CC1(C2=CC=CC=C2)N3C4=C(C=C(C=C4)C(=O)N)N=C3NC5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B1K3RM	2-(4-Sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	25164661	C22H18F3N5O3S	489.5	C1=CC=C(C(=C1)CN2C3=C(C=C(C=C3)C(=O)N)N=C2NC4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B1QK6V	2-(2-Morpholinoethylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45271267	C22H23F3N4O3	448.4	C1COCCN1CCNC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B1ZC9E	2-(3-Aminopyrrolidin-1-yl)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45267863	C20H19F3N4O2	404.4	C1CN(CC1N)C2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B2GIV6	2-(4-Methylbenzylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45271263	C24H20F3N3O2	439.4	CC1=CC=C(C=C1)CNC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B3O1YG	N-(2-Methoxyphenyl)-2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45271261	C29H24F3N5O4S	595.6	COC1=CC=CC=C1NC(=O)C2=CC3=C(C=C2)N(C(=N3)NC4=CC=C(C=C4)S(=O)(=O)N)CC5=CC=CC=C5C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B47ZWX	1-(Benzo[b]thiophen-3-ylmethyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45272991	C23H19N5O3S2	477.6	C1=CC=C2C(=C1)C(=CS2)CN3C4=C(C=C(C=C4)C(=O)N)N=C3NC5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B4N0UX	2-(4-Methoxyphenylamino)-N-methyl-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45267860	C24H21F3N4O2	454.4	CNC(=O)C1=CC2=C(C=C1)N(C(=N2)NC3=CC=C(C=C3)OC)CC4=CC=CC=C4C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B4VY0X	2-(4-Sulfamoylbenzylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45267020	C23H19F3N4O4S	504.5	C1=CC=C(C(=C1)CN2C3=C(C=C(C=C3)C(=O)O)N=C2NCC4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B6CKO1	Methyl 2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylate	Investigative	45272152	C24H20F3N3O2S	471.5	COC(=O)C1=CC2=C(C=C1)N(C(=N2)NC3=CC=C(C=C3)SC)CC4=CC=CC=C4C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B8BX3W	1-(2-Methoxybenzyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45268781	C22H21N5O4S	451.5	COC1=CC=CC=C1CN2C3=C(C=C(C=C3)C(=O)N)N=C2NC4=CC=C(C=C4)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	B9TIU3	2-(4-(Methylsulfonyl)phenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	25165473	C23H18F3N3O4S	489.5	CS(=O)(=O)C1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BAB1P7	2-(4-Methoxybenzylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45268741	C24H20F3N3O3	455.4	COC1=CC=C(C=C1)CNC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BB4Y9I	2-(4-Sulfamoylphenylamino)-1-(1-(2-(trifluoromethyl)phenyl)ethyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45271285	C23H20F3N5O3S	503.5	CC(C1=CC=CC=C1C(F)(F)F)N2C3=C(C=C(C=C3)C(=O)N)N=C2NC4=CC=C(C=C4)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BCE2I8	1-(Pyridin-2-ylmethyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45272183	C20H18N6O3S	422.5	C1=CC=NC(=C1)CN2C3=C(C=C(C=C3)C(=O)N)N=C2NC4=CC=C(C=C4)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BD7MW6	2-(4-(Methylthio)phenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	25165475	C23H18F3N3O2S	457.5	CSC1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BG5XZ7	N-Methyl-2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45268737	C23H20F3N5O3S	503.5	CNC(=O)C1=CC2=C(C=C1)N(C(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)CC4=CC=CC=C4C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BH1CZ3	4-(5-(Pyrrolidine-1-carbonyl)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazol-2-ylamino)benzenesulfonamide	Investigative	45269596	C26H24F3N5O3S	543.6	C1CCN(C1)C(=O)C2=CC3=C(C=C2)N(C(=N3)NC4=CC=C(C=C4)S(=O)(=O)N)CC5=CC=CC=C5C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BH3E9F	1-(Benzo[d]thiazol-2-ylmethyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45267896	C22H18N6O3S2	478.6	C1=CC=C2C(=C1)N=C(S2)CN3C4=C(C=C(C=C4)C(=O)N)N=C3NC5=CC=C(C=C5)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BH3EL9	2-(4-Sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	25164662	C22H17F3N4O4S	490.5	C1=CC=C(C(=C1)CN2C3=C(C=C(C=C3)C(=O)O)N=C2NC4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BH6E7I	N-(2-Methoxyphenyl)-2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45266928	C30H25F3N4O3	546.5	COC1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)NC5=CC=CC=C5OC	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BJ03MF	Methyl 2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylate	Investigative	45272994	C23H19F3N4O4S	504.5	COC(=O)C1=CC2=C(C=C1)N(C(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)CC4=CC=CC=C4C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BJX2C6	Methyl 2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylate	Investigative	45270431	C24H20F3N3O3	455.4	COC1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)OC	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BL1E9S	2-((4-Methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	25165471	C23H19F3N4O2	440.4	COC1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BL4U0V	(2e)-2-(3-Fluoranyl-4-Methoxy-Phenyl)imino-1-[[2-(Trifluoromethyl)phenyl]methyl]-3h-Benzimidazole-5-Carboxylic Acid	Investigative	25165666	C23H17F4N3O3	459.4	COC1=C(C=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BQ6G0U	1-[2-(Trifluoromethyl)benzyl]-2-[[4-(methylsulfonyl)phenyl]amino]-1H-benzoimidazole-5-carboxamide	Investigative	25165474	C23H19F3N4O3S	488.5	CS(=O)(=O)C1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BRB43O	1-(2,3-Dimethoxybenzyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	25165472	C23H23N5O5S	481.5	COC1=CC=CC(=C1OC)CN2C3=C(C=C(C=C3)C(=O)N)N=C2NC4=CC=C(C=C4)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BU3L8J	2-(4-(Methylsulfonyl)benzylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	45272155	C24H20F3N3O4S	503.5	CS(=O)(=O)C1=CC=C(C=C1)CNC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BVW2L1	1-((5-Chlorobenzo[b]thiophen-3-yl)methyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45267851	C23H18ClN5O3S2	512	C1=CC(=CC=C1NC2=NC3=C(N2CC4=CSC5=C4C=C(C=C5)Cl)C=CC(=C3)C(=O)N)S(=O)(=O)N	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BXBF04	N,N-Dimethyl-2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	45269595	C24H22F3N5O3S	517.5	CN(C)C(=O)C1=CC2=C(C=C1)N(C(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)CC4=CC=CC=C4C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BXGA15	2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide	Investigative	25165854	C23H18F4N4O2	458.4	COC1=C(C=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)N)F	IC50 ~ 50000 nM	Poor binder
T93716	Kinesin heavy chain neuron-specific 1	BY0Z2C	2-(4-Methoxyphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid	Investigative	25164463	C23H18F3N3O3	441.4	COC1=CC=C(C=C1)NC2=NC3=C(N2CC4=CC=CC=C4C(F)(F)F)C=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder