TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T94324	Histone deacetylase 10	D0M8FD	SNDX-275	Phase 2	4261	C21H20N4O3	376.4	C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3	IC50 = 50100 nM	Poor binder
T94324	Histone deacetylase 10	B07CXW	Chembl4215954	Investigative	145974425	C23H17FN2O3	388.4	C1=CC(=CC=C1CN2C=CC3=C2C=CC(=C3)C(=O)C4=CC=C(C=C4)F)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	B0GAH1	Pimelic Diphenylamide 106	Investigative	16070100	C20H25N3O2	339.4	CC1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N	IC50 = 66200 nM	Poor binder
T94324	Histone deacetylase 10	B0LZI8	N-Hydroxy-E-3-(4''-methoxybiphenyl-4-yl)-acrylamide	Investigative	15986509	C16H15NO3	269.29	COC1=CC=C(C=C1)C2=CC=C(C=C2)/C=C/C(=O)NO	IC50 = 91000 nM	Poor binder
T94324	Histone deacetylase 10	B0OD5E	Chembl4206537	Investigative	145978805	C23H17ClN2O3	404.8	C1=CC(=CC=C1CN2C=CC3=C2C=CC(=C3)C(=O)C4=CC=C(C=C4)Cl)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	B0VTQ6	N-(2-Aminophenyl)-7,7-di(1H-indol-3-yl)heptanamide	Investigative	45271073	C29H30N4O	450.6	C1=CC=C2C(=C1)C(=CN2)C(CCCCCC(=O)NC3=CC=CC=C3N)C4=CNC5=CC=CC=C54	IC50 = 73000 nM	Poor binder
T94324	Histone deacetylase 10	B13SGM	(2E,4E)-5-[4-[3-(1-Adamantyl)-4-methoxyphenyl]phenyl]-N-hydroxypenta-2,4-dienamide	Investigative	90654947	C28H31NO3	429.5	COC1=C(C=C(C=C1)C2=CC=C(C=C2)/C=C/C=C/C(=O)NO)C34CC5CC(C3)CC(C5)C4	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	B29EOY	Onc(cccc=1N=C(SC=1)\\C=C\\C1=CC=CC=C1)=O	Investigative	102514716	C15H16N2O2S	288.4	C1=CC=C(C=C1)/C=C/C2=NC(=CS2)CCCC(=O)NO	IC50 = 78310 nM	Poor binder
T94324	Histone deacetylase 10	BA8BT9	(E)-3-[4-[3-(1-Adamantyl)-4-(cyanomethyl)phenyl]-3-chlorophenyl]-N-hydroxyprop-2-enamide	Investigative	90654946	C27H27ClN2O2	447	C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=C(C=C(C=C5)/C=C/C(=O)NO)Cl)CC#N	IC50 = 63900 nM	Poor binder
T94324	Histone deacetylase 10	BC05YB	E,E-5-(4''-Methoxybiphenyl-4-yl)-penta-2,4-dienoic acid Nhydroxyamide	Investigative	42631047	C18H17NO3	295.3	COC1=CC=C(C=C1)C2=CC=C(C=C2)/C=C/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BHB09K	2-(2,2-Dimethylpropanoyl)-N-hydroxy-1,3-dihydroisoindole-5-carboxamide	Investigative	58147224	C14H18N2O3	262.3	CC(C)(C)C(=O)N1CC2=C(C1)C=C(C=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T94324	Histone deacetylase 10	BI97WY	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3,4,5-tetrahydro-2-benzazepine-7-carboxamide	Investigative	58147302	C17H19N3O3	313.35	CN1C=CC=C1C(=O)N2CCCC3=C(C2)C=CC(=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T94324	Histone deacetylase 10	BJ90QD	3-[(2E,4E)-5-(3,4-Dimethoxyphenyl)penta-2,4-dienoyl]-7-methoxychromen-2-one	Investigative	118709095	C23H20O6	392.4	COC1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)/C=C/C=C/C3=CC(=C(C=C3)OC)OC	IC50 = 85000 nM	Poor binder
T94324	Histone deacetylase 10	BKP54S	Chembl4218915	Investigative	145970786	C27H24N2O8S	536.6	COC1=CC(=CC(=C1OC)OC)C(=O)C2=CC3=C(C=C2)N(C=C3)S(=O)(=O)C4=CC=CC(=C4)/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BL3W7B	Chembl4214502	Investigative	145974125	C25H20N2O6S	476.5	COC1=CC=C(C=C1)C(=O)C2=CC3=C(C=C2)N(C=C3)S(=O)(=O)C4=CC=C(C=C4)/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BL5RX8	2-[5-(3-Nitrophenyl)furfuryl]-1,2,3,4-tetrahydroisoquinoline-7-carbohydroximic acid	Investigative	101882265	C21H19N3O5	393.4	C1CN(CC2=C1C=CC(=C2)C(=O)NO)CC3=CC=C(O3)C4=CC(=CC=C4)[N+](=O)[O-]	IC50 = 71100 nM	Poor binder
T94324	Histone deacetylase 10	BNJI96	(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	Investigative	92045024	C20H19N5O2	361.4	C1CC2=C(C[C@@H]1NC3=NC=CC(=N3)C4=CN=CC=C4)C=C(C=C2)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BP9E6M	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide	Investigative	49831258	C16H17N3O3	299.32	CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T94324	Histone deacetylase 10	BQIC95	Chembl4209463	Investigative	145966594	C24H20N2O3	384.4	CC1=CC=C(C=C1)C(=O)C2=CC3=C(C=C2)N(C=C3)CC4=CC=C(C=C4)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BQXH02	Chembl4218266	Investigative	138393071	C24H20N2O4	400.4	COC1=CC=C(C=C1)C(=O)C2=CC3=C(C=C2)N(C=C3)CC4=CC=C(C=C4)C(=O)NO	IC50 = 59800 nM	Poor binder
T94324	Histone deacetylase 10	BR6BY4	N-Hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]isoindoline-5-carboxamide	Investigative	58147189	C15H15N3O3	285.3	CN1C=CC=C1C(=O)N2CC3=C(C2)C=C(C=C3)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T94324	Histone deacetylase 10	BRH7M9	N-(2-Aminophenyl)-4-[[[(4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-ylidene]amino]methyl]benzamide	Investigative	136110961	C29H26N4O2	462.5	C1=CC=C(C=C1)[C@@H]2[C@@H](OC(=NCC3=CC=C(C=C3)C(=O)NC4=CC=CC=C4N)N2)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BS8PG9	2-(2,2-Dimethylpropanoyl)-N-hydroxy-3,4-dihydro-1H-isoquinoline-6-carboxamide	Investigative	49855444	C15H20N2O3	276.33	CC(C)(C)C(=O)N1CCC2=C(C1)C=CC(=C2)C(=O)NO	IC50 ~ 50000 nM	Poor binder
T94324	Histone deacetylase 10	BTA14N	(E)-3-[4-[3-(1-Adamantyl)-4-hydroxyphenyl]phenyl]-N-hydroxyprop-2-enamide	Investigative	15986417	C25H27NO3	389.5	C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC=C(C=C5)/C=C/C(=O)NO)O	IC50 ~ 100000 nM	Poor binder
T94324	Histone deacetylase 10	BXFN05	Chembl4202838	Investigative	145977003	C27H24N2O8S	536.6	COC1=CC(=CC(=C1OC)OC)C(=O)C2=CC3=C(C=C2)N(C=C3)S(=O)(=O)C4=CC=C(C=C4)/C=C/C(=O)NO	IC50 ~ 100000 nM	Poor binder