TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T95682 Bromodomain adjacent to zinc finger 2A B2ISO1 4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide Investigative 137636309 C20H19N3O3S 381.4 CCC1=CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)C#N)N(C1=O)CC IC50 ~ 100000 nM Poor binder T95682 Bromodomain adjacent to zinc finger 2A B5W6SY 4-[3-[2-(4-Methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrile Investigative 118733101 C15H14N6 278.31 CC1=CN(N=N1)CCN2C=NC=C2C3=CC=C(C=C3)C#N IC50 ~ 50000 nM Poor binder T95682 Bromodomain adjacent to zinc finger 2A B6P9ZN 4-[3-Methyl-5-(1-methylpyrazol-4-yl)imidazol-4-yl]benzonitrile Investigative 118733102 C15H13N5 263.3 CN1C=C(C=N1)C2=C(N(C=N2)C)C3=CC=C(C=C3)C#N IC50 ~ 50000 nM Poor binder T95682 Bromodomain adjacent to zinc finger 2A BAV60C 4-[3-[2-(4-Methyltriazol-1-yl)ethyl]-5-pyridin-3-ylimidazol-4-yl]benzonitrile Investigative 118733098 C20H17N7 355.4 CC1=CN(N=N1)CCN2C=NC(=C2C3=CC=C(C=C3)C#N)C4=CN=CC=C4 IC50 ~ 50000 nM Poor binder T95682 Bromodomain adjacent to zinc finger 2A BI52TL 4-[5-(3-Methyl-1,2-oxazol-5-yl)-3-[2-(4-methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrile Investigative 118733100 C19H17N7O 359.4 CC1=NOC(=C1)C2=C(N(C=N2)CCN3C=C(N=N3)C)C4=CC=C(C=C4)C#N IC50 ~ 50000 nM Poor binder T95682 Bromodomain adjacent to zinc finger 2A D07HET PMID25719566C1 Investigative 50967109 C21H18N6 354.4 CC1=CN(N=N1)CCN2C=NC(=C2C3=CC=C(C=C3)C#N)C4=CC=CC=C4 IC50 = 51000 nM Poor binder