TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T95736	Serine/threonine-protein kinase NIK	D0Z5DM	IMD-0354	Phase 1	5081913	C15H8ClF6NO2	383.67	C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)O	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B0A8LD	4-(4-Bromophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	17229016	C10H10BrN3	252.11	CC1=C(C(=NN1)N)C2=CC=C(C=C2)Br	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B0C1DP	1,4-Dihydro-3(2H)-isoquinolinone	Investigative	90469	C9H9NO	147.17	C1C2=CC=CC=C2CNC1=O	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B0GOK5	4-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-amine	Investigative	71560661	C13H13N5	239.28	CC1=CC2=NC(=C(N2C=C1)C3=NC(=NC=C3)N)C	IC50 ~ 80000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B0VRX8	Chembl4286561	Investigative	145990026	C17H17N3O	279.34	CC1=C(C(=NN1)N)C2=CC=C(C=C2)OCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B1ECY3	4-(3-Chlorophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	12330558	C10H10ClN3	207.66	CC1=C(C(=NN1)N)C2=CC(=CC=C2)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B23JHS	Chembl4281464	Investigative	43157763	C10H9Cl2N3	242.1	CC1=C(NN=C1N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B26XDG	Chembl4280454	Investigative	62900145	C12H15N3	201.27	CC1=C(C=C(C=C1)C2=C(NN=C2N)C)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B28TJX	Chembl4292701	Investigative	145989643	C16H12Cl2N4O	347.2	CC1=C(C(=NN1C(=O)C2=CN=CC=C2)N)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B2GND6	3-Methyl-4-(3-methylphenyl)-1H-pyrazol-5-amine	Investigative	25219675	C11H13N3	187.24	CC1=CC(=CC=C1)C2=C(NN=C2N)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B2J7OE	Chembl4283909	Investigative	61992815	C10H9Cl2N3	242.1	CC1=C(C(=NN1)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B37ZTK	Chembl4166474	Investigative	145952913	C10H6F3N3O2S	289.24	C1=CC(=CC(=C1)NC(=O)C2=NSNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B4XPM8	Chembl4284120	Investigative	145992355	C12H12ClN3O	249.69	CC1=NN(C(=C1C2=CC(=CC=C2)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B53QDN	Chembl4294749	Investigative	145993951	C12H7F6N3O2S	371.26	COC1=NSN=C1C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B5HDA2	Chembl4279494	Investigative	145980076	C11H6F6N4O2	340.18	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NON=C2N)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B5QDZ2	Chembl4288356	Investigative	145991401	C14H13N3	223.27	CC1=C(C(=NN1)N)C2=CC3=CC=CC=C3C=C2	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B64GVF	Chembl4280373	Investigative	145979893	C14H15Cl2N3O	312.2	CCCC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B6PEN8	3-Methyl-4-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine	Investigative	2782960	C11H10F3N3	241.21	CC1=C(C(=NN1)N)C2=CC(=CC=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B7A8XY	Chembl4284415	Investigative	82482456	C11H11Cl2N3	256.13	CC1=C(C(=NN1C)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B7CI5V	4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinamine	Investigative	6539018	C12H11N5	225.25	CC1=C(N2C=CC=CC2=N1)C3=NC(=NC=C3)N	IC50 ~ 80000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B8DQ3O	Chembl4286012	Investigative	145993088	C15H17Cl2N3O2	342.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)OC(C)(C)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B8WX4N	Chembl4284828	Investigative	145992596	C15H15Cl2N3O	324.2	CC1=C(C(=NN1C(=O)C2CCC2)N)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B9B0GW	2,7-Naphthyridine-1,3,6,8-tetrone	Investigative	46911431	C8H8N2O4	196.16	C1C2CC(=O)NC(=O)C2C(=O)NC1=O	IC50 = 90000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B9T0GB	3-Methyl-4-phenyl-1H-pyrazol-5-amine	Investigative	599501	C10H11N3	173.21	CC1=C(C(=NN1)N)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	B9WLO4	Chembl4292088	Investigative	145989390	C12H9F6N3	309.21	CC1=C(C(=NN1)N)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BAWF21	Chembl4294725	Investigative	145993662	C13H12F3N3O	283.25	CC1=NN(C(=C1C2=CC(=CC=C2)C(F)(F)F)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BBW1V3	Chembl4287493	Investigative	145990918	C12H12ClN3O	249.69	CC1=NN(C(=C1C2=CC=C(C=C2)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BC3K6A	Isoquinoline-1,3(2H,4H)-dione	Investigative	349435	C9H7NO2	161.16	C1C2=CC=CC=C2C(=O)NC1=O	IC50 = 51000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BCWX74	4-(Ethoxymethylidene)-1,2,3,4-tetrahydroisoquinoline-1,3-dione	Investigative	8891610	C12H11NO3	217.22	CCO/C=C/1\\C2=CC=CC=C2C(=O)NC1=O	IC50 ~ 50000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BE5AX6	4-(2,8-Dimethylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-amine	Investigative	71560662	C13H13N5	239.28	CC1=CC=CN2C1=NC(=C2C3=NC(=NC=C3)N)C	IC50 ~ 80000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BE6P2G	Chembl4290916	Investigative	145987124	C16H12Cl2N4O	347.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BESX34	Chembl4291313	Investigative	145988918	C13H13Cl2N3O	298.16	CCC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BG51KO	Chembl4284710	Investigative	145991710	C11H5F6N3O2S	357.23	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NSNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BHR4O6	4-(4-Chlorophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	575802	C10H10ClN3	207.66	CC1=C(C(=NN1)N)C2=CC=C(C=C2)Cl	IC50 = 61100 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BHWX34	Chembl4283382	Investigative	145990524	C12H8Cl2F3N3O	338.11	CC1=C(C(=NN1)NC(=O)C(F)(F)F)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BJ4D0E	Chembl4290266	Investigative	145989760	C14H11F6N3O2	367.25	CC1=C(C(=O)NN1C)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BK5IC4	Chembl4288230	Investigative	145992947	C6H8BrN3O	218.05	CC1=NN(C(=C1Br)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BK7CG0	4-(3-Bromophenyl)-3-methyl-1H-pyrazol-5-amine	Investigative	43560957	C10H10BrN3	252.11	CC1=C(C(=NN1)N)C2=CC(=CC=C2)Br	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BKY2B1	Chembl4280067	Investigative	145981688	C12H8F6N4O2	354.21	CN1C(=C(N=N1)O)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BM8UA7	4-(Thiophen-2-ylmethylene)isoquinoline-1,3(2H,4H)-dione	Investigative	10777396	C14H9NO2S	255.29	C1=CC=C2C(=C1)/C(=C\\C3=CC=CS3)/C(=O)NC2=O	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BNUA75	Chembl4291646	Investigative	61992242	C11H11Cl2N3	256.13	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BO7XJ5	3-Methyl-4-(4-methylphenyl)-1H-pyrazol-5-amine	Investigative	24219848	C11H13N3	187.24	CC1=CC=C(C=C1)C2=C(NN=C2N)C	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BPN6A8	4-(2H-1,3-Benzodioxol-5-yl)-5-methyl-1H-pyrazol-3-amine	Investigative	43157843	C11H11N3O2	217.22	CC1=C(C(=NN1)N)C2=CC3=C(C=C2)OCO3	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BQ7SJ6	Chembl4278086	Investigative	145979124	C13H14Cl2N4O	313.18	CCNC(=O)N1C(=C(C(=N1)C)C2=CC(=C(C=C2)Cl)Cl)N	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BS9T2K	Chembl4283501	Investigative	145992122	C12H8F6N4O2	354.21	CN1NC(=O)C(=N1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BTO21Q	Chembl4287264	Investigative	145991820	C17H11ClN4O	322.7	C1=CC(=CN=C1)C(=O)NC2=CC3=C(C4=C(N3)C=NC=C4)C(=C2)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BUNM27	Chembl4283080	Investigative	145981824	C13H9F6N3O2	353.22	CN1C=C(C(=O)N1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BUS0C5	5,7-Dichloro-1H-quinazoline-2,4-dione	Investigative	1508801	C8H4Cl2N2O2	231.03	C1=C(C=C(C2=C1NC(=O)NC2=O)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BVJ41C	Chembl4279585	Investigative	145980083	C14H14ClN3O	275.73	CC1=NN(C(=C1C2=CC=C(C=C2)Cl)N)C(=O)C3CC3	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BVT56Q	Chembl4277586	Investigative	145984375	C12H11Cl2N3O	284.14	CC1=C(C(=NN1C(=O)C)N)C2=CC(=C(C=C2)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BW4N7G	Chembl4287256	Investigative	145991367	C11H5F6N3O3	341.17	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BW7J3F	Chembl4282760	Investigative	145979774	C11H10F3N3O	257.209	CC1=C(C(=NN1)N)C2=CC(=CC=C2)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BX2T9M	Chembl4281003	Investigative	145981500	C16H12Cl2N4O	347.2	CC1=C(C(=NN1)NC(=O)C2=CC=CC=N2)C3=CC(=C(C=C3)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BXG7C1	Chembl4293673	Investigative	145987461	C11H6F6N4O2	340.18	C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=NNNC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BZ4KV5	Chembl4177097	Investigative	145971744	C10H6F3N3O3	273.17	C1=CC(=CC(=C1)NC(=O)C2=NONC2=O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	BZI24E	Chembl4283047	Investigative	145980681	C16H12Cl2N4O	347.2	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C3=CC=NC=C3	IC50 = 58200 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	D07MQC	PS-1145	Investigative	9949093	C17H11ClN4O	322.7	C1=CC(=CN=C1)C(=O)NC2=CC(=CC3=C2NC4=C3C=CN=C4)Cl	IC50 ~ 100000 nM	Poor binder
T95736	Serine/threonine-protein kinase NIK	D0P0IE	Plumbagin	Investigative	10205	C11H8O3	188.18	CC1=CC(=O)C2=C(C1=O)C=CC=C2O	IC50 ~ 100000 nM	Poor binder