TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97155	Serine/threonine-protein kinase ATR	D09SFV	LY294002	Terminated	3973	C19H17NO3	307.3	C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	B4G2QZ	Methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605035	C22H27N7O3	437.5	COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	B4VM0G	Tert-butyl 4-[6-[4-(2-fluoroethylcarbamoylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate	Investigative	44605429	C28H37FN8O4	568.6	CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NCCF)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	BK0SX5	Isopropyl 4-(6-{4-[(cyclopropylcarbamoyl)amino]phenyl}-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605427	C28H36N8O4	548.6	CC(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NC5CC5)N6CCOCC6	IC50 ~ 50000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	BLER53	Tert-butyl 4-[6-[4-(cyclopropylcarbamoylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate	Investigative	44605430	C29H38N8O4	562.7	CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NC5CC5)N6CCOCC6	IC50 ~ 50000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	BS58IK	Isopropyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino}phenyl)-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate	Investigative	44605426	C27H35FN8O4	554.6	CC(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NCCF)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	D05USL	KU-55933	Investigative	5278396	C21H17NO3S2	395.5	C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4	IC50 ~ 100000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	D0T0BY	2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one	Investigative	10039361	C16H15N3O2	281.31	C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2	IC50 ~ 100000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	D0W1ST	Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate	Investigative	9860529	C17H15NO3	281.3	C1COCCN1C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3	IC50 ~ 100000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	D0X7TB	2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one	Investigative	10017389	C18H17NO3	295.3	CC1CN(CCO1)C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3	IC50 ~ 100000 nM	Poor binder
T97155	Serine/threonine-protein kinase ATR	D0Y3OO	NU-7432	Investigative	11327430	C25H19NO3S	413.5	C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56	IC50 ~ 100000 nM	Poor binder