TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97747	HUMAN C-C chemokine receptor 5	B0CTW9	4-[4-[[(3S)-1-Butyl-3-[(S)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	23577461	C33H44ClN3O6	614.2	CCCCN1C(=O)[C@@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@H](C5CCCCC5)O.Cl	IC50 = 51000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0GX9B	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-hexyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	56678577	C36H51ClN4O5	655.3	CCCCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)NC)[C@@H](C5CCCCC5)O.Cl	IC50 = 110000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0H2XD	2,2'-Bipyridine	Investigative	1474	C10H8N2	156.18	C1=CC=NC(=C1)C2=CC=CC=N2	IC50 = 79432.82 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0JZ8T	N-(4-((E)-3-Oxo-5-(3,4-dihydroxyphenyl)-4-pentenyl)phenyl)-2-thienylacetamide	Investigative	129908557	C23H21NO4S	407.5	C1=CSC(=C1)CC(=O)NC2=CC=C(C=C2)CCC(=O)/C=C/C3=CC(=C(C=C3)O)O	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0QC1M	(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-9-[(4-phenoxyphenyl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione;hydrochloride	Investigative	23577403	C32H44ClN3O4	570.2	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=CC=C4)[C@@H](C5CCCCC5)O.Cl	IC50 = 53000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0UFC5	N-[5-[1-[[4-(Diethylamino)phenyl]methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]benzamide	Investigative	73351054	C32H41N3O2	499.7	CCN(CC)C1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OC(C)C)NC(=O)C4=CC=CC=C4	IC50 = 138000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0V1OX	N-[2-Ethoxy-5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]phenyl]pyrazine-2-carboxamide	Investigative	73346461	C25H27N5O4	461.5	CCOC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)[N+](=O)[O-])NC(=O)C4=NC=CN=C4	IC50 = 61000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0VWI3	N-[5-[1-[[4-(Diethylamino)phenyl]methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	73352529	C30H39N5O2	501.7	CCN(CC)C1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OC(C)C)NC(=O)C4=NC=CN=C4	IC50 = 61000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B0W5PJ	Methyl 4-[[4-[4-propan-2-yloxy-3-(pyrazine-2-carbonylamino)phenyl]piperazin-1-yl]methyl]benzenesulfonate	Investigative	90656336	C26H31N5O5S	525.6	CC(C)OC1=C(C=C(C=C1)N2CCN(CC2)CC3=CC=C(C=C3)S(=O)(=O)OC)NC(=O)C4=NC=CN=C4	IC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B15DIM	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-(3-hydroxybutyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	56657985	C34H47ClN4O6	643.2	CC(CCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)NC)[C@@H](C5CCCCC5)O)O.Cl	IC50 = 180000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B15UGR	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-ethyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	56661525	C32H43ClN4O5	599.2	CCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)NC)[C@@H](C5CCCCC5)O.Cl	IC50 = 178000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B1J7FU	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-2,5-dioxo-1-pentyl-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	56681916	C35H49ClN4O5	641.2	CCCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)NC)[C@@H](C5CCCCC5)O.Cl	IC50 = 68000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B27GQW	4-Cyano-N-[[8-[[(4-cyanobenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride	Investigative	122185628	C28H26ClN5O2	500	CC1=C(C(=[N+]2CCCC2=C1CNC(=O)C3=CC=C(C=C3)C#N)C)CNC(=O)C4=CC=C(C=C4)C#N.[Cl-]	IC50 = 101200 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B2QE3U	N-(4-((E)-3-Oxo-5-(3,4-dihydroxyphenyl)-4-pentenyl)phenyl)cyclohexanecarboxamide	Investigative	129908214	C24H27NO4	393.5	C1CCC(CC1)C(=O)NC2=CC=C(C=C2)CCC(=O)/C=C/C3=CC(=C(C=C3)O)O	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B3L7YM	N-[5-[1-[(4-Nitrophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	73349499	C26H29N5O4	475.5	CC(C)OC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)[N+](=O)[O-])NC(=O)C4=NC=CN=C4	IC50 = 65700 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B3UN8Z	5-[[4-(4-Benzyl-1H-pyrazol-5-yl)-1-piperidyl]methyl]-2-methoxy-pyrimidine	Investigative	56754672	C21H25N5O	363.5	COC1=NC=C(C=N1)CN2CCC(CC2)C3=C(C=NN3)CC4=CC=CC=C4	IC50 = 70000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B4ZHX5	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-methyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	56657983	C31H41ClN4O5	585.1	CNC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)CN3CCC4(CC3)C(=O)N[C@@H](C(=O)N4C)[C@@H](C5CCCCC5)O.Cl	IC50 = 59000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B4ZUM6	N-[5-[1-[[4-(Diethylamino)phenyl]methyl]piperidin-4-yl]-2-ethoxyphenyl]pyrazine-2-carboxamide	Investigative	73351060	C29H37N5O2	487.6	CCN(CC)C1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OCC)NC(=O)C4=NC=CN=C4	IC50 = 51800 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B5GJ2B	4-Fluoro-N-[[8-[[(4-fluorobenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride	Investigative	122185626	C26H26ClF2N3O2	486	CC1=C(C(=[N+]2CCCC2=C1CNC(=O)C3=CC=C(C=C3)F)C)CNC(=O)C4=CC=C(C=C4)F.[Cl-]	IC50 = 80900 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B5PZ1F	N-[5-[1-[(4-Acetamidophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]benzamide	Investigative	73352528	C30H35N3O3	485.6	CC(C)OC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)NC(=O)C)NC(=O)C4=CC=CC=C4	IC50 = 92200 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B6BZ1Q	N-(4-((E)-3-Oxo-5-(3,4-diacetoxyphenyl)-4-pentenyl)phenyl)benzamide	Investigative	129908240	C28H25NO6	471.5	CC(=O)OC1=C(C=C(C=C1)/C=C/C(=O)CCC2=CC=C(C=C2)NC(=O)C3=CC=CC=C3)OC(=O)C	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B6GH9U	Fuscinarin	Investigative	10445499	C14H16O5	264.27	CC1C2=C(C(=C3C(=C2C(=O)O1)CCC(O3)(C)C)O)O	IC50 = 80000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B72XPF	Benzyl ethyl{1-[3-phenyl-5-(phenylsulfonyl)heptyl]piperidin-4-yl}carbamate	Investigative	483350	C34H44N2O4S	576.8	CCC(CC(CCN1CCC(CC1)N(CC)C(=O)OCC2=CC=CC=C2)C3=CC=CC=C3)S(=O)(=O)C4=CC=CC=C4	IC50 = 88000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B7EF5H	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-(2-methoxyethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	23577327	C33H45ClN4O6	629.2	CNC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)CN3CCC4(CC3)C(=O)N[C@@H](C(=O)N4CCOC)[C@@H](C5CCCCC5)O.Cl	IC50 = 98000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B7L2ZM	N-(4-((E)-3-Oxo-5-(3,4-diacetoxyphenyl)-4-pentenyl)phenyl)-2-thienylacetamide	Investigative	129908112	C27H25NO6S	491.6	CC(=O)OC1=C(C=C(C=C1)/C=C/C(=O)CCC2=CC=C(C=C2)NC(=O)CC3=CC=CS3)OC(=O)C	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B7WQ3C	[(1R,2S,3S,5R,6R,8S,10E,12R,13S,15R,16S,17R,18S)-18-Benzyl-6-hydroxy-6,8,15,16-tetramethyl-7,20-dioxo-4,14-dioxa-19-azapentacyclo[10.8.0.01,17.03,5.013,15]icos-10-en-2-yl] acetate	Investigative	44559501	C30H37NO7	523.6	C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@@]2([C@@H]([C@H]5[C@@H](O5)[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]4CC6=CC=CC=C6)C)C	IC50 = 60000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B8BX0Q	N-[5-[1-[(4-Aminophenyl)methyl]piperidin-4-yl]-2-ethoxyphenyl]benzamide	Investigative	73347961	C27H31N3O2	429.6	CCOC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)N)NC(=O)C4=CC=CC=C4	IC50 = 63000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B8OG4D	4-[4-[[(3R)-1-Butyl-3-[(R)-cyclobutyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	56661523	C31H40ClN3O6	586.1	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCC5)O.Cl	IC50 = 66000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B91PLB	1,10-Phenanthroline	Investigative	1318	C12H8N2	180.2	C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1	IC50 = 50118.72 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B9KB3T	(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-9-[[4-(4-methoxyphenoxy)phenyl]methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione;hydrochloride	Investigative	23577377	C33H46ClN3O5	600.2	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)OC)[C@@H](C5CCCCC5)O.Cl	IC50 = 91000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B9L3XU	Abametapir	Investigative	15664	C12H12N2	184.24	CC1=CN=C(C=C1)C2=NC=C(C=C2)C	IC50 = 199526.23 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B9S0TK	Neocuproine	Investigative	65237	C14H12N2	208.26	CC1=NC2=C(C=C1)C=CC3=C2N=C(C=C3)C	EC50 = 63095.73 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	B9UE7V	N-[5-[1-[[4-(Diethylamino)phenyl]methyl]piperidin-4-yl]-2-methoxyphenyl]benzamide	Investigative	73351055	C30H37N3O2	471.6	CCN(CC)C1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OC)NC(=O)C4=CC=CC=C4	IC50 = 90000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BA8OE5	N-[[5,7-Dimethyl-8-[[(4-nitrobenzoyl)amino]methyl]-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]-4-nitrobenzamide;chloride	Investigative	122185624	C26H26ClN5O6	540	CC1=C(C(=[N+]2CCCC2=C1CNC(=O)C3=CC=C(C=C3)[N+](=O)[O-])C)CNC(=O)C4=CC=C(C=C4)[N+](=O)[O-].[Cl-]	IC50 = 67700 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BBNO01	4-[4-[[(3R)-1-Butyl-3-[(R)-cyclopropyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	56661521	C30H38ClN3O6	572.1	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CC5)O.Cl	IC50 = 81000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BC1HB9	N-[5-[1-[(4-Acetamidophenyl)methyl]piperidin-4-yl]-2-ethoxyphenyl]benzamide	Investigative	73346460	C29H33N3O3	471.6	CCOC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)NC(=O)C)NC(=O)C4=CC=CC=C4	IC50 = 115000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BDA91Z	N-[5-[4-[(4-Cyanophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	90656331	C26H28N6O2	456.5	CC(C)OC1=C(C=C(C=C1)N2CCN(CC2)CC3=CC=C(C=C3)C#N)NC(=O)C4=NC=CN=C4	IC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BDT4S3	N-[4-[5-(3,4-Dihydroxyphenyl)-3-oxo-pentyl]phenyl]-2-(2-thienyl)acetamide	Investigative	129908560	C23H23NO4S	409.5	C1=CSC(=C1)CC(=O)NC2=CC=C(C=C2)CCC(=O)CCC3=CC(=C(C=C3)O)O	EC50 = 55370 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BE3B4A	N-(4-((E)-3-Oxo-5-(3,4-dihydroxyphenyl)-4-pentenyl)phenyl)benzamide	Investigative	129908179	C24H21NO4	387.4	C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)CCC(=O)/C=C/C3=CC(=C(C=C3)O)O	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BE4QT9	3,5-Bis[(Z)-dec-1-enyl]-2,4,6-trimethylpyridine	Investigative	62707285	C28H47N	397.7	CCCCCCCC/C=C\\C1=C(C(=C(N=C1C)C)/C=C\\CCCCCCCC)C	IC50 ~ 100000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BF78QI	N-[5-[1-[(4-Acetamidophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]benzamide	Investigative	73346454	C28H31N3O3	457.6	CC(=O)NC1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OC)NC(=O)C4=CC=CC=C4	IC50 = 70800 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BFS14W	N-[2-Methoxy-5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]phenyl]pyrazine-2-carboxamide	Investigative	73355552	C24H25N5O4	447.5	COC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)[N+](=O)[O-])NC(=O)C4=NC=CN=C4	IC50 = 73000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BFZ3N9	N-[5-[1-[[4-(Diethylamino)phenyl]methyl]piperidin-4-yl]-2-ethoxyphenyl]benzamide	Investigative	73357100	C31H39N3O2	485.7	CCN(CC)C1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OCC)NC(=O)C4=CC=CC=C4	IC50 = 64000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BGF39E	N-[5-[1-[(4-Acetamidophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	73349500	C28H33N5O3	487.6	CC(C)OC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)NC(=O)C)NC(=O)C4=NC=CN=C4	IC50 = 88100 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BHU17J	1,10-Phenanthroline-2,9-dicarbaldehyde	Investigative	602123	C14H8N2O2	236.22	C1=CC2=C(C3=C1C=CC(=N3)C=O)N=C(C=C2)C=O	IC50 = 125892.54 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BJMN10	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-heptyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]-N-methylbenzamide;hydrochloride	Investigative	56664938	C37H53ClN4O5	669.3	CCCCCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)NC)[C@@H](C5CCCCC5)O.Cl	IC50 = 190000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BKPC35	4-[4-[[(3R)-1-Butyl-3-[(S)-hydroxy-(4-hydroxycyclohexyl)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	56678573	C33H44ClN3O7	630.2	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@H](C5CCC(CC5)O)O.Cl	IC50 = 129000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BLZP61	2,9-Bis(bromomethyl)-1,10-phenanthroline	Investigative	353741	C14H10Br2N2	366.05	C1=CC2=C(C3=C1C=CC(=N3)CBr)N=C(C=C2)CBr	IC50 = 199526.23 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BM3H8J	1-Cyclohexyl-4-[(2-fluorophenyl)-[1-[(4-fluorophenyl)methyl]tetrazol-5-yl]methyl]piperazine	Investigative	3209888	C25H30F2N6	452.5	C1CCC(CC1)N2CCN(CC2)C(C3=CC=CC=C3F)C4=NN=NN4CC5=CC=C(C=C5)F	IC50 = 79400 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BMDA05	(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-9-[[4-(4-hydroxyphenoxy)phenyl]methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione;hydrochloride	Investigative	23577369	C32H44ClN3O5	586.2	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)O)[C@@H](C5CCCCC5)O.Cl	IC50 = 68000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BMQ7L9	N-[5-[1-[(4-Aminophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	73355549	C26H31N5O2	445.6	CC(C)OC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)N)NC(=O)C4=NC=CN=C4	IC50 = 77800 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BMWC42	3,5-Bis[(Z)-dec-1-enyl]-2-(3-methoxypropyl)-4,6-dimethylpyridine	Investigative	62707286	C31H53NO	455.8	CCCCCCCC/C=C\\C1=C(C(=C(N=C1C)CCCOC)/C=C\\CCCCCCCC)C	IC50 ~ 100000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BN03JB	4-Methyl-1,10-phenanthroline	Investigative	93149	C13H10N2	194.23	CC1=C2C=CC3=C(C2=NC=C1)N=CC=C3	IC50 = 63095.73 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BN9O0P	4-[4-[[(3R)-1-Butyl-3-[(S)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	53324597	C33H44ClN3O6	614.2	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@H](C5CCCCC5)O.Cl	IC50 = 182000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BO3FG4	N-[5-[1-[(4-Aminophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]benzamide	Investigative	73354018	C28H33N3O2	443.6	CC(C)OC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)N)NC(=O)C4=CC=CC=C4	IC50 = 66200 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BO3YD8	N-[5-[4-[(3-Nitrophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	90656327	C25H28N6O4	476.5	CC(C)OC1=C(C=C(C=C1)N2CCN(CC2)CC3=CC(=CC=C3)[N+](=O)[O-])NC(=O)C4=NC=CN=C4	IC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BQ7N3J	N-[[5,7-Dimethyl-8-[[[4-(trifluoromethyl)benzoyl]amino]methyl]-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]-4-(trifluoromethyl)benzamide;chloride	Investigative	122185622	C28H26ClF6N3O2	586	CC1=C(C(=[N+]2CCCC2=C1CNC(=O)C3=CC=C(C=C3)C(F)(F)F)C)CNC(=O)C4=CC=C(C=C4)C(F)(F)F.[Cl-]	IC50 = 121500 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BQS94X	4-[4-[[(3R)-1-Butyl-3-[(R)-hydroxy-(4-hydroxycyclohexyl)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	56675255	C33H44ClN3O7	630.2	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCC(CC5)O)O.Cl	IC50 = 140000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BR3SI2	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-2,5-dioxo-1-propyl-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	23577447	C32H42ClN3O6	600.1	CCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCCCC5)O.Cl	IC50 = 112000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BR8M7U	N-[5-[1-[(4-Acetamidophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]pyrazine-2-carboxamide	Investigative	73352534	C26H29N5O3	459.5	CC(=O)NC1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OC)NC(=O)C4=NC=CN=C4	IC50 = 59000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BRX49M	10-Methoxydihydrofuscin	Investigative	10425374	C16H20O6	308.33	CC1C2=C(C(=C3C(=C2C(C(=O)O1)OC)CCC(O3)(C)C)O)O	IC50 = 154000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BT5Q8P	4-[4-[[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-methyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	56664934	C30H38ClN3O6	572.1	CN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCCCC5)O.Cl	IC50 = 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BTEN79	N-[5-[4-[(3,5-Dinitrophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	90656329	C25H27N7O6	521.5	CC(C)OC1=C(C=C(C=C1)N2CCN(CC2)CC3=CC(=CC(=C3)[N+](=O)[O-])[N+](=O)[O-])NC(=O)C4=NC=CN=C4	IC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BU5WP6	N-[4-[(E)-5-(3,4-Dihydroxyphenyl)-3-oxo-pent-4-enyl]phenyl]-4-nitro-benzamide	Investigative	129908213	C24H20N2O6	432.4	C1=CC(=CC=C1CCC(=O)/C=C/C2=CC(=C(C=C2)O)O)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BU67TD	N-(4-((E)-3-Oxo-5-(3,4-dihydroxyphenyl)-4-pentenyl)phenyl)-p-methylbenzamide	Investigative	129908215	C25H23NO4	401.5	CC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)CCC(=O)/C=C/C3=CC(=C(C=C3)O)O	EC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BV42MK	N-[5-[1-[[4-(Diethylamino)phenyl]methyl]piperidin-4-yl]-2-methoxyphenyl]pyrazine-2-carboxamide	Investigative	73349506	C28H35N5O2	473.6	CCN(CC)C1=CC=C(C=C1)CN2CCC(CC2)C3=CC(=C(C=C3)OC)NC(=O)C4=NC=CN=C4	IC50 = 56000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BV9B4P	4-Amino-N-[[8-[[(4-aminobenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride	Investigative	122185630	C26H30ClN5O2	480	CC1=C(C(=[N+]2CCCC2=C1CNC(=O)C3=CC=C(C=C3)N)C)CNC(=O)C4=CC=C(C=C4)N.[Cl-]	IC50 = 173900 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BX5D1N	4-[4-[[(3R)-1-Butyl-3-[(R)-hydroxy(oxan-4-yl)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride	Investigative	56671868	C32H42ClN3O7	616.1	CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCOCC5)O.Cl	IC50 = 120000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BXCE65	N-[5-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide	Investigative	90656332	C25H28FN5O2	449.5	CC(C)OC1=C(C=C(C=C1)N2CCN(CC2)CC3=CC=C(C=C3)F)NC(=O)C4=NC=CN=C4	IC50 ~ 50000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BXOV76	4-Methoxy-N-[[8-[[(4-methoxybenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride	Investigative	122185634	C28H32ClN3O4	510	CC1=C(C(=[N+]2CCCC2=C1CNC(=O)C3=CC=C(C=C3)OC)C)CNC(=O)C4=CC=C(C=C4)OC.[Cl-]	IC50 = 69000 nM	Poor binder
T97747	HUMAN C-C chemokine receptor 5	BYG73M	N-[5-[1-[(4-Aminophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]benzamide	Investigative	73347956	C26H29N3O2	415.5	COC1=C(C=C(C=C1)C2CCN(CC2)CC3=CC=C(C=C3)N)NC(=O)C4=CC=CC=C4	IC50 = 77000 nM	Poor binder