TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98264	Protein-tyrosine phosphatase SHP-1	B0BZ5V	5-(1H-Indol-3-ylmethyl)-3-[6-(3-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazole	Investigative	127028684	C23H18N4O	366.4	CC1=CC(=CC=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B0KC2T	3-[6-(4-Ethoxyphenyl)pyridin-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127028686	C24H20N4O2	396.4	CCOC1=CC=C(C=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B15PRL	5-(1H-Indol-3-ylmethyl)-3-[3-(4-propoxyphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127028346	C26H23N3O2	409.5	CCCOC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B20KQZ	4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenol	Investigative	127027703	C23H17N3O2	367.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=CC(=C4)C5=CC=C(C=C5)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B2CSL6	H-Glu-Gly-Leu-Asn-pTyr-Met-Val-Phe-NH2	Investigative	44401149	C45H66N9O16PS	1052.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=CC=C2)N	EC50 = 140000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B2MB1Z	H-Glu-Gly-Leu-Asn-pTyr-Met-Val-Abu(betaPh)-NH2	Investigative	44401229	C46H68N9O16PS	1066.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@@H](CCSC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C2=CC=CC=C2)N	EC50 = 80000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B2XVS3	2-(3-Bromoanilino)-5-hydroxybenzothiazole-6-carboxylic acid	Investigative	101884098	C14H9BrN2O3S	365.2	C1=CC(=CC(=C1)Br)NC2=NC3=C(S2)C=C(C(=C3)O)C(=O)O	IC50 = 78000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B36JDQ	(S)-2-(4-(Benzamidomethyl)-1H-1,2,3-triazol-1-yl)-3-(4-hydroxyphenyl)propanoic acid	Investigative	53320581	C19H18N4O4	366.4	C1=CC=C(C=C1)C(=O)NCC2=CN(N=N2)[C@@H](CC3=CC=C(C=C3)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B3VYR4	5-(1H-Indol-3-ylmethyl)-3-[5-(3-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127025572	C22H17N3OS	371.5	CC1=CC(=CC=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B4LUR3	Triazole tetra-benzyloxy-beta-D-O-galactosyl Tyrosine	Investigative	53321875	C46H47N3O9	785.9	C1=CC=C(C=C1)COC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)OCC3=CN(N=N3)[C@@H](CC4=CC=C(C=C4)O)C(=O)O)OCC5=CC=CC=C5)OCC6=CC=CC=C6)OCC7=CC=CC=C7	IC50 = 53100 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B4N9VB	5-(1H-Indol-3-ylmethyl)-3-[5-(4-propylphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127025574	C24H21N3OS	399.5	CCCC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B4XD8T	H-Glu-Gly-Leu-Asn-pTyr-Nle-Val-Phe-NH2	Investigative	44387848	C49H66N9O16P	1068.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=CC=C3)N	EC50 = 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B5BT3G	(2S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-amino-3-phenylbutanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]pentanedioic acid	Investigative	44401230	C46H68N9O16PS	1066.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@@H](CCSC)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](C(C)C2=CC=CC=C2)N	EC50 = 180000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B5GV6K	H-Glu-Gly-Leu-Asn-pTyr-Met-Val-Leu-NH2	Investigative	44401147	C42H68N9O16PS	1018.1	CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)N	EC50 = 160000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B5I0AF	(2S)-3-[[1-[[(2R,3S,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid	Investigative	56680547	C39H48N4O10	732.8	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)C[C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)C(=O)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B6C3VF	5-[(E)-2-Phenylvinyl]-3-bromo-2-hydroxybenzoic acid	Investigative	44563589	C15H11BrO3	319.15	C1=CC=C(C=C1)/C=C/C2=CC(=C(C(=C2)Br)O)C(=O)O	IC50 = 140000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B6D7BV	H-Glu-Gly-Leu-Asn-pTyr-Phe-Val-Leu-NH2	Investigative	44401148	C46H68N9O16P	1034.099	CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OP(=O)(O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)N	EC50 = 70000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B6I4CH	5-[(E)-2-Phenylvinyl]-2-hydroxybiphenyl-3-carboxylic acid	Investigative	44563590	C21H16O3	316.3	C1=CC=C(C=C1)/C=C/C2=CC(=C(C(=C2)C(=O)O)O)C3=CC=CC=C3	IC50 = 78000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B6NO4I	2-(3-(Dihydroxymethyl)naphthalen-2-ylamino)-2-oxoacetic acid	Investigative	45483667	C13H11NO5	261.23	C1=CC=C2C=C(C(=CC2=C1)C(O)O)NC(=O)C(=O)O	Ki = 94000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B6Q7TJ	5-(1H-Indol-3-ylmethyl)-3-[3-(4-propylphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127027706	C26H23N3O	393.5	CCCC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B6RY4E	(2S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-phenylbutanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]pentanedioic acid	Investigative	73345604	C46H68N9O16PS	1066.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC2=CC=CC=C2)N	EC50 = 75000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B79XZG	3-(3-Bromophenyl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027399	C17H12BrN3O	354.2	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC(=CC=C4)Br	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B7G1LP	H-Glu-Gly-Leu-Asn-pTyr-Met-Val-Ser(betaPh)-NH2	Investigative	44401113	C45H66N9O17PS	1068.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@@H](CCSC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C2=CC=CC=C2)O)N	EC50 = 85000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B7KA2Y	5-(1H-Indol-3-ylmethyl)-3-[5-(4-propoxyphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127025577	C24H21N3O2S	415.5	CCCOC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B80UNQ	5-Benzyl-2-hydroxybiphenyl-3-carboxylic acid	Investigative	19779154	C20H16O3	304.3	C1=CC=C(C=C1)CC2=CC(=C(C(=C2)C(=O)O)O)C3=CC=CC=C3	IC50 = 129000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B82MAO	Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-(1H-imidazol-5-yl)propanoate	Investigative	57380664	C15H19N3NaO6P	391.29	CCOP(=O)(C(C1=CC=CC=C1O)N[C@@H](CC2=CN=CN2)C(=O)[O-])O.[Na+]	IC50 = 167000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B86FMP	Triazole tetra-benzyloxy-beta-D-O-glucosyl Threonine	Investigative	53316640	C41H47N3O8	709.8	C[C@H]([C@@H](CO)N1C=C(N=N1)CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B8MSX2	Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-hydroxypropanoate	Investigative	57380433	C12H17NNaO7P	341.23	CCOP(=O)(C(C1=CC=CC=C1O)N[C@@H](CO)C(=O)[O-])O.[Na+]	IC50 = 129000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B8TK9P	4-[5-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]aniline	Investigative	118722143	C21H16N4OS	372.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=C(S4)C5=CC=C(C=C5)N	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B96PFA	3-{2-[(3Z)-5-{[(3-Chloro-4-fluorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid	Investigative	135924018	C22H16ClFN4O5S	502.9	C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC(=C(C=C4)F)Cl)O)C(=O)O	IC50 = 122800 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B98RTA	3-Ethynyl-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	Investigative	71597177	C17H10O4	278.26	C#CC1=C(OC2=CC(=C(C=C21)C(=O)O)O)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B9J7KO	4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]aniline	Investigative	118722144	C23H18N4O	366.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=CC(=C4)C5=CC=C(C=C5)N	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B9NUQ0	(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[[1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]triazol-4-yl]methoxy]propanoic acid	Investigative	56670423	C17H28N4O10	448.4	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B9OQ6W	Triazole tetra-benzyloxy-beta-D-O-glucosyl Serine	Investigative	53317937	C40H43N3O9	709.8	C1=CC=C(C=C1)COC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OCC3=CN(N=N3)[C@@H](CO)C(=O)O)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B9PNV5	(2S)-3-[[1-[[(2R,3R,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid	Investigative	56660070	C39H48N4O10	732.8	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)C(=O)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	B9WVP4	3-{2-[(3Z)-5-({[4-Chloro-3-(trifluoromethyl)phenyl]methyl}sulfamoyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid	Investigative	135924020	C23H16ClF3N4O5S	552.9	C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC(=C(C=C4)Cl)C(F)(F)F)O)C(=O)O	IC50 = 74200 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BA2ZM3	3-(5-Bromothiophen-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027398	C15H10BrN3OS	360.2	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=C(S4)Br	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BCQ27J	5-(1H-Indol-3-ylmethyl)-3-[6-(2-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazole	Investigative	127028683	C23H18N4O	366.4	CC1=CC=CC=C1C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BCZ8J1	2-(Carboxyformamido)thiophene-3-carboxylic acid	Investigative	44359237	C7H5NO5S	215.19	C1=CSC(=C1C(=O)O)NC(=O)C(=O)O	Ki = 60000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BD04NS	2-Hydroxy-5-[4-[4-[[(2R,3R,4S,5R,6S)-3,4,5-tribenzoyloxy-6-methoxyoxan-2-yl]methoxymethyl]triazol-1-yl]butoxy]benzoic acid	Investigative	56681854	C42H41N3O13	795.8	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COCC2=CN(N=N2)CCCCOC3=CC(=C(C=C3)O)C(=O)O)OC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)OC(=O)C6=CC=CC=C6	IC50 = 68900 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BD26ER	(2S,3S)-3-[[1-[[(2R,3S,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid	Investigative	56683882	C40H50N4O10	746.8	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)C[C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BD5G7T	3-[5-(4-Ethylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127025573	C23H19N3OS	385.5	CCC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BD83JV	5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid	Investigative	44563588	C15H12O3	240.25	C1=CC=C(C=C1)/C=C/C2=CC(=C(C=C2)O)C(=O)O	IC50 = 126000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BEF67A	3-(6-Bromopyridin-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027724	C16H11BrN4O	355.19	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=NC(=CC=C4)Br	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BER3V1	(3Z)-3-[2-(3-Carboxyphenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid	Investigative	135924021	C16H11N3O5	325.27	C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)C(=O)O)O)C(=O)O	IC50 = 72500 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BF7ZA0	Methyl 4-[4-[5-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]phenoxy]butanoate	Investigative	127025578	C26H23N3O4S	473.5	COC(=O)CCCOC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BGOP20	3-[5-(4-Ethoxyphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127025576	C23H19N3O2S	401.5	CCOC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BGQ5Z0	4-[6-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl]phenol	Investigative	137174949	C22H16N4O2	368.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=CC(=N4)C5=CC=C(C=C5)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BH3X8O	(2S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-phenylbutanoyl]amino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]pentanedioic acid	Investigative	73351714	C47H70N9O16P	1048.099	CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OP(=O)(O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)N	EC50 = 140000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BH5PY3	2-Hydroxy-5-[5-[4-[[(2R,3R,4S,5R,6S)-3,4,5-tribenzoyloxy-6-methoxyoxan-2-yl]methoxymethyl]triazol-1-yl]pentoxy]benzoic acid	Investigative	56681855	C43H43N3O13	809.8	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COCC2=CN(N=N2)CCCCCOC3=CC(=C(C=C3)O)C(=O)O)OC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)OC(=O)C6=CC=CC=C6	IC50 = 52600 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BI8C5R	3-[3-(4-Ethoxyphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127028022	C25H21N3O2	395.5	CCOC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BI95BZ	Triazole tetra-benzyloxy-beta-D-O-glucosyl Tyrosine	Investigative	53320578	C41H45N3O9	723.8	C[C@H]([C@@H](C(=O)O)N1C=C(N=N1)CO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BJ73YB	6-Hydroxy-3-[2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethynyl]-2-phenyl-1-benzofuran-5-carboxylic acid	Investigative	71717989	C36H36O6	564.7	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4(C#CC5=C(OC6=CC(=C(C=C65)C(=O)O)O)C7=CC=CC=C7)O)C	IC50 ~ 100000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BJAG79	3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	3246406	C14H10N4O6S	362.32	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O)[N+](=O)[O-]	IC50 = 68000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BJUL08	(S)-3-Hydroxy-2-(4-(((2R,3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yloxy)methyl)-1H-1,2,3-triazol-1-yl)propanoic acid	Investigative	53324565	C40H43N3O9	709.8	C1=CC=C(C=C1)COC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)OCC3=CN(N=N3)[C@@H](CO)C(=O)O)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BK5UV3	Methyl 4-[4-[3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenoxy]butanoate	Investigative	127028347	C28H25N3O4	467.5	COC(=O)CCCOC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BKO4Z1	5-(1H-Indol-3-ylmethyl)-3-[3-(3-methylphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127027705	C24H19N3O	365.4	CC1=CC(=CC=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BKRQ36	6-Hydroxy-3-(3-hydroxyprop-1-ynyl)-2-phenyl-benzofuran-5-carboxylic acid	Investigative	71561559	C18H12O5	308.3	C1=CC=C(C=C1)C2=C(C3=CC(=C(C=C3O2)O)C(=O)O)C#CCO	IC50 ~ 100000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BL05RS	(S)-2-[2-((S)-2-{(S)-2-[(S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-methyl-pentanoylamino)-3-methyl-butyrylamino]-3-phenyl-butyrylamino}-3-(4-phosphonooxy-phenyl)-propionylamino]-3-carbamoyl-propionylamino}-4-methyl-pentanoylamino)-acetylamino]-pentanedioic acid	Investigative	44401026	C47H70N9O16P	1048.099	CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OP(=O)(O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)N	EC50 = 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BM2G4S	3-[5-(4-Butylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127025575	C25H23N3OS	413.5	CCCCC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BNA5G2	(3Z)-3-[2-(2-Nitrophenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide	Investigative	135924010	C14H11N5O5S	361.33	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)N)O)[N+](=O)[O-]	IC50 = 103700 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BNG14E	3-[3-(4-Butylphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027707	C27H25N3O	407.5	CCCCC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BNKS16	(2S,3S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[[1-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]triazol-4-yl]methoxy]butanoic acid	Investigative	56673908	C46H54N4O10	822.9	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BOA31L	5-(1H-Indol-3-ylmethyl)-3-[3-(2-methylphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127027704	C24H19N3O	365.4	CC1=CC=CC=C1C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BOEU56	3,4,6-Tribromo-5-[(2,3,6-tribromo-4,5-dihydroxyphenyl)methyl]benzene-1,2-diol	Investigative	21778115	C13H6Br6O4	705.6	C(C1=C(C(=C(C(=C1Br)Br)O)O)Br)C2=C(C(=C(C(=C2Br)Br)O)O)Br	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BOS14J	3-[6-(4-Butylphenyl)pyridin-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127028685	C26H24N4O	408.5	CCCCC1=CC=C(C=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BP21WV	5-Chloro-1-[[5-[(E)-(5-chloro-2-oxo-1H-indol-3-ylidene)methyl]furan-2-yl]methyl]indole-2,3-dione	Investigative	71461531	C22H12Cl2N2O4	439.2	C1=CC2=C(C=C1Cl)/C(=C\\C3=CC=C(O3)CN4C5=C(C=C(C=C5)Cl)C(=O)C4=O)/C(=O)N2	IC50 ~ 100000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BPG6R2	3-[(3-Acetyl-2-methyl-1-benzofuran-5-yl)sulfamoyl]benzoic acid	Investigative	1159989	C18H15NO6S	373.4	CC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C3=CC=CC(=C3)C(=O)O)C(=O)C	IC50 = 85000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BQ8F1K	4-{2-[(3Z)-5-{[(2-Chlorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid	Investigative	135924027	C22H17ClN4O5S	484.9	C1=CC=C(C(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=C(C=C4)C(=O)O)O)Cl	IC50 = 60800 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BS58AM	5-(1H-Indol-3-ylmethyl)-3-[6-(4-propoxyphenyl)pyridin-2-yl]-1,2,4-oxadiazole	Investigative	127024952	C25H22N4O2	410.5	CCCOC1=CC=C(C=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BT2V4A	Azane;[[4-[2-[[4-[difluoro(phosphono)methyl]phenyl]methoxy]ethoxymethyl]phenyl]-difluoromethyl]phosphonic acid	Investigative	49796692	C18H32F4N4O8P2	570.4	C1=CC(=CC=C1COCCOCC2=CC=C(C=C2)C(F)(F)P(=O)(O)O)C(F)(F)P(=O)(O)O.N.N.N.N	IC50 = 61000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BTIY32	H-Glu-Gly-Leu-Asn-pTyr-Phe-Val-Phe-NH2	Investigative	44387849	C49H66N9O17PS	1116.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CC=CC=C3)N	EC50 = 150000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BU2BS9	(2S)-3-[[1-[[(2R,3R,4S,5S,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid	Investigative	56670422	C39H48N4O10	732.8	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)C(=O)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BVD3K2	(2S)-2-[[2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]pentanedioic acid	Investigative	73351713	C46H68N9O16P	1034.099	CCCC[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=CC=C2)N	EC50 = 60000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BW7VS3	4-[Acetyl(6,7,8,9-tetrahydrodibenzofuran-2-yl)sulfamoyl]benzoic acid	Investigative	2964738	C21H19NO6S	413.4	CC(=O)N(C1=CC2=C(C=C1)OC3=C2CCCC3)S(=O)(=O)C4=CC=C(C=C4)C(=O)O	IC50 = 160000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BWQ06J	5-(1H-Indol-3-ylmethyl)-3-[5-(2-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127027725	C22H17N3OS	371.5	CC1=CC=CC=C1C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BXT2S9	(2S,3S)-3-[[1-[[(2R,3R,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid	Investigative	56673907	C40H50N4O10	746.8	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BY3N8X	Methyl (2S)-2-[4-(benzamidomethyl)triazol-1-yl]-3-(4-hydroxyphenyl)propanoate	Investigative	53319270	C20H20N4O4	380.4	COC(=O)[C@H](CC1=CC=C(C=C1)O)N2C=C(N=N2)CNC(=O)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BY9Z5U	2-(Carboxyformamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid	Investigative	4774445	C11H11NO5S	269.28	C1CCC2=C(C1)C(=C(S2)NC(=O)C(=O)O)C(=O)O	Ki = 100000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BYJ82Z	1-[[5-[(E)-(5-Bromo-2-oxo-1H-indol-3-ylidene)methyl]furan-2-yl]methyl]indole-2,3-dione	Investigative	71456091	C22H13BrN2O4	449.3	C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC=C(O3)/C=C/4\\C5=C(C=CC(=C5)Br)NC4=O	IC50 ~ 100000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BZ8EL6	3-{2-[(3Z)-5-{[2-(2,4-Dichlorophenyl)ethyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid	Investigative	135924029	C23H18Cl2N4O5S	533.4	C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCCC4=C(C=C(C=C4)Cl)Cl)O)C(=O)O	IC50 = 73400 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BZM6L4	5,5''-Methylenebis(2-hydroxybiphenyl-3-carboxylic acid)	Investigative	17748269	C27H20O6	440.4	C1=CC=C(C=C1)C2=C(C(=CC(=C2)CC3=CC(=C(C(=C3)C(=O)O)O)C4=CC=CC=C4)C(=O)O)O	IC50 = 51000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	BZTU59	(2S,3S)-3-[[1-[[(2R,3R,4S,5S,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid	Investigative	56683883	C40H50N4O10	746.8	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	D0SJ2Q	OLEANOLIC_ACID	Investigative	10494	C30H48O3	456.7	C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O	IC50 ~ 120000 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	D0U8IF	[(125)I] RB129	Investigative	10114	C30H46O4	470.7	C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O	IC50 = 65400 nM	Poor binder
T98264	Protein-tyrosine phosphatase SHP-1	D0Y1RO	Novo Nordisk a/S Compound	Investigative	1829	C9H6INO5	335.05	C1=CC(=C(C=C1I)C(=O)O)NC(=O)C(=O)O	Ki = 80000 nM	Poor binder