TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T98642 PDZ binding kinase B3WDG4 [1-(2-Thiophen-2-yl-1H-imidazo[4,5-b]pyridin-7-yl)piperidin-3-yl]methanamine Investigative 49856448 C16H19N5S 313.4 C1CC(CN(C1)C2=C3C(=NC=C2)N=C(N3)C4=CC=CS4)CN IC50 = 77000 nM Poor binder T98642 PDZ binding kinase BF1V9G N-(3-Aminophenyl)-2-thiophen-2-yl-1H-imidazo[4,5-b]pyridine-7-carboxamide Investigative 49856066 C17H13N5OS 335.4 C1=CC(=CC(=C1)NC(=O)C2=C3C(=NC=C2)N=C(N3)C4=CC=CS4)N IC50 = 96000 nM Poor binder T98642 PDZ binding kinase BZTY59 (S)-Tert-Butyl 3-(2-(5-bromothiophen-2-yl)-7-hydroxy-1H-benzo[d]imidazole-4-carboxamido)piperidine-1-carboxylate Investigative 46219387 C22H25BrN4O4S 521.4 CC(C)(C)OC(=O)N1CCC[C@@H](C1)NC(=O)C2=C3C(=C(C=C2)O)NC(=N3)C4=CC=C(S4)Br IC50 = 100000 nM Poor binder