Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 45 48 0 0 0 0 0 0 0 0999 V2000 -1.3594 -0.8382 -2.3179 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8696 -1.2676 -3.5386 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3108 -1.9819 -3.6044 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6685 -1.1220 -1.1502 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5206 -1.8408 -1.2093 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0109 -2.2717 -2.4420 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1984 -2.9537 -2.1872 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4208 -2.9385 -0.8595 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4261 -2.2743 -0.2412 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3754 -3.4483 -0.3028 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1512 -0.6989 0.0482 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2604 0.0875 0.0479 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1363 1.4608 0.1872 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2689 2.2633 0.1811 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5259 1.6886 0.0352 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6479 0.3158 -0.1039 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5177 -0.4851 -0.0977 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1450 3.6513 0.3222 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.9975 4.2646 -0.0292 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8208 5.7086 0.2335 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1078 3.6304 -0.5621 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.8407 6.4392 0.8453 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6723 7.7871 1.0889 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4959 8.4175 0.7285 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4758 7.6990 0.1190 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6315 6.3450 -0.1241 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6783 8.3241 -0.2336 O 0 0 0 0 0 0 0 0 0 0 0 0 0.7733 9.7209 0.0528 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6413 9.9245 1.4305 F 0 0 0 0 0 0 0 0 0 0 0 0 2.0167 10.2007 -0.3725 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.2452 10.4050 -0.6194 F 0 0 0 0 0 0 0 0 0 0 0 0 -5.6289 2.4689 0.0296 F 0 0 0 0 0 0 0 0 0 0 0 0 -3.6381 -1.8238 -0.2335 F 0 0 0 0 0 0 0 0 0 0 0 0 -5.8701 -0.2425 -0.2452 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.2808 -0.2763 -2.2751 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4131 -1.0434 -4.4446 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6883 -2.3149 -4.5599 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7683 -3.3690 -2.8533 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3519 -2.1233 0.7141 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1590 1.9063 0.3008 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.8851 4.1711 0.6729 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7612 5.9500 1.1275 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4621 8.3513 1.5624 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3699 9.4726 0.9214 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1612 5.7850 -0.5978 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 35 1 0 0 0 0 2 3 1 0 0 0 0 2 36 1 0 0 0 0 3 6 2 0 0 0 0 3 37 1 0 0 0 0 4 11 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 38 1 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 39 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 40 1 0 0 0 0 14 18 1 0 0 0 0 14 15 2 0 0 0 0 15 32 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 34 1 0 0 0 0 17 33 1 0 0 0 0 18 19 1 0 0 0 0 18 41 1 0 0 0 0 19 20 1 0 0 0 0 19 21 2 0 0 0 0 20 22 2 0 0 0 0 20 26 1 0 0 0 0 22 23 1 0 0 0 0 22 42 1 0 0 0 0 23 24 2 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 25 26 2 0 0 0 0 25 27 1 0 0 0 0 26 45 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 28 30 1 0 0 0 0 28 31 1 0 0 0 0 M END > 697353 > Serine/threonine-protein kinase B-raf > Homo sapiens > 20148563 > J. Med. Chem.|2010|53|5|1964 > 78 > 2010 > 697353 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 20148563 > J. Med. Chem.|2010|53|5|1964 > 78 > 2010 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 63 67 0 0 0 0 0 0 0 0999 V2000 -0.0158 1.3148 0.0093 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1327 -0.7073 -0.0121 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3100 -0.1182 -0.0202 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3568 1.2892 -0.0135 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5695 1.9893 -0.0217 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5528 3.3742 -0.0151 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3339 4.0728 -0.0002 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1481 3.4089 0.0085 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1310 2.0050 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2023 -0.6841 0.0099 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2165 -2.1490 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7261 6.4509 -2.2269 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8908 6.5251 -3.2459 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7394 5.8677 -3.2756 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3402 5.0672 -2.2488 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1756 4.9357 -1.1260 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8295 4.1245 -0.0232 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7002 4.0401 1.0514 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8990 4.7428 1.0490 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2532 5.5322 -0.0055 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4014 5.6448 -1.1122 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3433 3.1780 2.2348 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9184 7.1553 -2.2522 N 0 0 0 0 0 0 0 0 0 0 0 0 9.3657 8.6843 -3.5133 N 0 0 0 0 0 0 0 0 0 0 0 0 9.2887 9.3211 -4.7586 N 0 0 0 0 0 0 0 0 0 0 0 0 8.1615 8.9799 -5.3284 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4770 8.1144 -4.4712 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2379 7.9442 -3.3547 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4689 8.7923 -2.5555 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6823 9.4426 -6.6802 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5782 10.4864 -6.5001 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8498 10.0627 -7.4504 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1323 8.2482 -7.4625 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2192 -0.7010 -0.0313 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5080 1.4550 -0.0328 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3393 5.1528 0.0048 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2197 3.9607 0.0206 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0376 -0.1910 0.0205 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7147 -2.5125 -0.8946 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6977 -2.5220 0.8852 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2475 -2.5024 0.0101 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0994 5.9704 -4.1394 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3974 4.5425 -2.2962 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5622 4.6627 1.8977 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1894 6.0703 0.0128 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7254 2.1693 2.0779 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7868 3.5982 3.1375 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2594 3.1429 2.3450 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5308 7.0992 -1.5021 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5153 7.6608 -4.6606 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2809 9.6245 -1.8771 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5454 7.8675 -1.9836 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4012 8.9652 -3.0931 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7465 10.0445 -5.9514 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9701 11.3372 -5.9428 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2316 10.8210 -7.4778 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2416 10.9136 -6.8931 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6363 9.3191 -7.5787 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5031 10.3974 -8.4281 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7856 8.5829 -8.4402 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9188 7.5046 -7.5908 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3005 7.8064 -6.9138 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 10 2 0 0 0 0 2 3 2 0 0 0 0 2 11 1 0 0 0 0 3 4 1 0 0 0 0 4 5 2 0 0 0 0 4 35 1 0 0 0 0 5 6 1 0 0 0 0 5 10 1 0 0 0 0 6 7 2 0 0 0 0 6 36 1 0 0 0 0 7 8 1 0 0 0 0 7 18 1 0 0 0 0 8 9 2 0 0 0 0 8 37 1 0 0 0 0 9 10 1 0 0 0 0 9 38 1 0 0 0 0 11 12 1 0 0 0 0 11 39 1 0 0 0 0 12 40 1 0 0 0 0 12 41 1 0 0 0 0 12 42 1 0 0 0 0 13 14 2 0 0 0 0 13 22 1 0 0 0 0 13 24 1 0 0 0 0 14 15 1 0 0 0 0 15 16 2 0 0 0 0 15 43 1 0 0 0 0 16 17 1 0 0 0 0 16 44 1 0 0 0 0 17 18 1 0 0 0 0 17 22 2 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 19 23 1 0 0 0 0 20 21 2 0 0 0 0 20 45 1 0 0 0 0 21 22 1 0 0 0 0 21 46 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 23 49 1 0 0 0 0 24 29 1 0 0 0 0 24 50 1 0 0 0 0 25 26 1 0 0 0 0 25 29 1 0 0 0 0 25 30 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 27 31 1 0 0 0 0 28 29 2 0 0 0 0 28 51 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 32 1 0 0 0 0 31 34 1 0 0 0 0 31 33 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 32 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 33 60 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 34 63 1 0 0 0 0 M END > 674663 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 19 > 2009 > 674663 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 19 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 70 76 0 0 0 999 V2000 -0.0151 1.3181 0.0109 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1115 2.0206 -0.0032 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3074 1.4463 -0.0304 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0033 -0.0044 -0.0012 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2386 -0.6504 -0.0293 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4144 0.1270 -0.0441 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5900 -2.6613 -0.0726 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3579 -2.1134 -0.0450 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7268 -1.8725 -0.0853 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6427 -0.5063 -0.0720 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9930 -2.2293 -0.1096 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7849 -1.1276 -0.1134 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9373 -0.0087 -0.0894 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4753 1.2692 -0.0874 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8445 1.4373 -0.1090 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6871 0.3357 -0.1332 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1700 -0.9401 -0.1355 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3657 -2.8173 -0.0329 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0360 3.3987 0.0104 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.2099 4.0328 -0.0796 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7213 -4.0554 -0.0878 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7646 -4.7371 -1.2969 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8947 -6.1120 -1.3086 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9814 -6.8099 -0.1180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9386 -6.1341 1.0877 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8144 -4.7587 1.1060 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7684 -4.0229 2.4204 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6692 -3.9774 -2.5949 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4366 5.2185 0.6068 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6646 5.8436 0.5181 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6728 5.2866 -0.2578 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4458 4.1011 -0.9446 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2162 3.4787 -0.8597 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9175 5.9198 -0.3474 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8314 5.1644 -1.2155 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.2022 5.8450 -1.2236 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0563 7.2292 -1.6951 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.1423 7.9846 -0.8270 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7715 7.3040 -0.8188 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3629 7.8939 -1.7891 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9165 -0.5703 0.0111 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8243 2.1307 -0.0693 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2629 2.4330 -0.1074 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7573 0.4800 -0.1506 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8320 -1.7932 -0.1541 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8456 3.9282 0.0823 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9284 -6.6427 -2.2486 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0823 -7.8851 -0.1297 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0065 -6.6820 2.0159 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7807 -3.7529 2.7212 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1689 -3.1193 2.3102 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3224 -4.6643 3.1805 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6691 -3.6969 -2.9261 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1994 -4.6068 -3.3507 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0702 -3.0789 -2.4469 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3474 5.6516 1.2102 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8411 6.7653 1.0525 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2299 3.6677 -1.5478 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0395 2.5569 -1.3940 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4320 5.1390 -2.2294 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9329 4.1467 -0.8387 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.8735 5.3028 -1.8897 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6137 5.8461 -0.2143 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0408 9.0023 -1.2038 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5417 8.0100 0.1869 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1003 7.8462 -0.1528 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3601 7.3029 -1.8282 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.8352 7.9072 -0.8069 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.2259 8.9166 -2.1403 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.9971 7.3510 -2.4899 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 2 19 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 4 5 2 0 0 0 0 4 41 1 0 0 0 0 5 6 1 0 0 0 0 5 8 1 0 0 0 0 6 10 1 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 7 9 1 0 0 0 0 8 18 2 0 0 0 0 9 10 1 0 0 0 0 9 11 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 17 1 0 0 0 0 13 14 1 0 0 0 0 14 15 2 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 15 43 1 0 0 0 0 16 17 2 0 0 0 0 16 44 1 0 0 0 0 17 45 1 0 0 0 0 19 20 1 0 0 0 0 19 46 1 0 0 0 0 20 29 2 0 0 0 0 20 33 1 0 0 0 0 21 22 2 0 0 0 0 21 26 1 0 0 0 0 22 23 1 0 0 0 0 22 28 1 0 0 0 0 23 24 2 0 0 0 0 23 47 1 0 0 0 0 24 25 1 0 0 0 0 24 48 1 0 0 0 0 25 26 2 0 0 0 0 25 49 1 0 0 0 0 26 27 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 29 30 1 0 0 0 0 29 56 1 0 0 0 0 30 31 2 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 34 1 0 0 0 0 32 33 2 0 0 0 0 32 58 1 0 0 0 0 33 59 1 0 0 0 0 34 35 1 0 0 0 0 34 39 1 0 0 0 0 35 36 1 0 0 0 0 35 60 1 0 0 0 0 35 61 1 0 0 0 0 36 37 1 0 0 0 0 36 62 1 0 0 0 0 36 63 1 0 0 0 0 37 38 1 0 0 0 0 37 40 1 0 0 0 0 38 39 1 0 0 0 0 38 64 1 0 0 0 0 38 65 1 0 0 0 0 39 66 1 0 0 0 0 39 67 1 0 0 0 0 40 68 1 0 0 0 0 40 69 1 0 0 0 0 40 70 1 0 0 0 0 M END > 542187 > Serine/threonine-protein kinase B-raf > Homo sapiens > 18278858 > J. Med. Chem.|2008|51|6|1637 > 25 > 2008 > 542187 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18278858 > J. Med. Chem.|2008|51|6|1637 > 25 > 2008 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 62 67 0 0 0 0 0 0 0 0999 V2000 0.4268 1.0369 -0.8301 N 0 0 0 0 0 0 0 0 0 0 0 0 0.3304 -0.2116 -0.3429 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4426 -0.3823 0.6698 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1549 0.9511 0.6618 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2424 1.4345 1.3555 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6828 2.7267 1.1377 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0247 3.5338 0.2171 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9305 3.0468 -0.4806 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4862 1.7455 -0.2619 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4934 -1.0451 -0.6554 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4674 4.8405 -0.0054 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8165 5.1401 0.0880 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6981 4.1758 0.2730 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0009 4.4063 0.3640 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5184 5.6625 0.2723 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6432 6.7446 0.0748 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1052 8.0748 -0.0304 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1871 9.0942 -0.2253 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8286 8.8164 -0.3167 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3604 7.5390 -0.2178 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2553 6.4792 -0.0204 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5766 9.2055 0.3677 N 0 0 0 0 0 0 0 0 0 0 0 0 13.2131 9.6946 -0.6790 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6074 9.9361 -1.8400 N 0 0 0 0 0 0 0 0 0 0 0 0 11.3240 9.6968 -2.0100 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5895 9.1733 -0.9287 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2215 8.8918 -1.0307 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5518 8.3765 0.0667 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2342 8.1383 1.2715 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5614 8.4066 1.3878 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2690 8.9292 0.2935 C 0 0 0 0 0 0 0 0 0 0 0 0 14.5641 9.9681 -0.5658 N 0 0 0 0 0 0 0 0 0 0 0 0 15.2997 10.5120 -1.7101 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6665 10.5183 -0.3389 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8651 -0.6731 2.0564 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3935 -1.5005 0.2383 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1691 1.4023 -1.5026 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7509 0.8040 2.0699 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5348 3.1078 1.6811 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4217 3.6776 -1.1945 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8298 5.5378 -0.2251 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6712 3.5732 0.5157 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5833 5.8248 0.3502 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1308 9.6266 -0.4684 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3005 7.3447 -0.2912 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8454 9.8977 -2.9571 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6942 9.0747 -1.9553 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6963 7.7365 2.1175 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0712 8.2185 2.3212 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0246 9.7998 0.2712 H 0 0 0 0 0 0 0 0 0 0 0 0 16.3434 10.6613 -1.4334 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2415 9.8133 -2.5447 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8616 11.4659 -2.0035 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8738 10.7497 -1.3837 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8963 11.1920 0.0366 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5763 10.6434 0.2484 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2975 -1.6032 2.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6781 -0.7672 2.7762 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2081 0.1438 2.3550 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8108 -1.2651 -0.7408 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2008 -1.5915 0.9650 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8464 -2.4417 0.1833 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 9 1 0 0 0 0 1 37 1 0 0 0 0 2 3 1 0 0 0 0 2 10 2 0 0 0 0 3 4 1 0 0 0 0 3 35 1 0 0 0 0 3 36 1 0 0 0 0 4 5 1 0 0 0 0 4 9 2 0 0 0 0 5 6 2 0 0 0 0 5 38 1 0 0 0 0 6 7 1 0 0 0 0 6 39 1 0 0 0 0 7 8 2 0 0 0 0 7 11 1 0 0 0 0 8 9 1 0 0 0 0 8 40 1 0 0 0 0 11 12 1 0 0 0 0 11 41 1 0 0 0 0 12 13 2 0 0 0 0 12 21 1 0 0 0 0 13 14 1 0 0 0 0 14 15 2 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 15 43 1 0 0 0 0 16 17 1 0 0 0 0 16 21 2 0 0 0 0 17 18 2 0 0 0 0 17 28 1 0 0 0 0 18 19 1 0 0 0 0 18 34 1 0 0 0 0 19 20 2 0 0 0 0 19 44 1 0 0 0 0 20 21 1 0 0 0 0 20 45 1 0 0 0 0 22 23 1 0 0 0 0 22 31 2 0 0 0 0 23 24 2 0 0 0 0 23 32 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 46 1 0 0 0 0 26 27 1 0 0 0 0 26 31 1 0 0 0 0 27 28 2 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 29 30 2 0 0 0 0 29 48 1 0 0 0 0 30 31 1 0 0 0 0 30 49 1 0 0 0 0 32 33 1 0 0 0 0 32 50 1 0 0 0 0 33 51 1 0 0 0 0 33 52 1 0 0 0 0 33 53 1 0 0 0 0 34 54 1 0 0 0 0 34 55 1 0 0 0 0 34 56 1 0 0 0 0 35 57 1 0 0 0 0 35 58 1 0 0 0 0 35 59 1 0 0 0 0 36 60 1 0 0 0 0 36 61 1 0 0 0 0 36 62 1 0 0 0 0 M END > 674692 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 20 > 2009 > 674692 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 20 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 48 51 0 0 0 999 V2000 -0.0387 1.2705 -0.2278 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0234 0.0714 -0.4415 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.2088 1.8995 -0.0002 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4143 1.1945 -0.1032 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4793 -0.1321 0.3001 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7368 1.1301 -0.7049 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5464 1.8242 -0.6035 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8070 -0.1928 -0.2990 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6733 -0.8271 0.2033 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0003 -2.1117 0.5294 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.2371 -2.3800 -0.1572 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.8447 -1.0811 -0.2874 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.9895 -2.9354 -1.4172 F 0 0 0 0 0 0 0 0 0 0 0 0 -6.0483 -3.2280 0.6044 F 0 0 0 0 0 0 0 0 0 0 0 0 2.6771 0.1489 -0.6820 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0488 -0.3194 -0.8945 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0381 -1.8037 -1.1552 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9225 -2.2846 -2.4442 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9125 -3.5820 -2.6839 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0121 -4.4693 -1.7068 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1315 -4.0559 -0.3846 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1502 -2.7016 -0.1022 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4341 1.4911 -0.4223 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1727 2.0022 -0.2127 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3399 3.7321 0.0772 S 0 0 0 0 0 0 0 0 0 0 0 0 3.0349 3.6136 -0.1041 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3871 2.3939 -0.3476 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9967 -5.8306 -2.0060 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7740 -6.2402 -3.2706 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6575 -7.5551 -3.5424 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6782 -5.4235 -4.1661 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4154 -8.0003 -4.9170 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2158 2.8406 0.2350 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5990 -0.6223 0.6889 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6161 1.6220 -1.0936 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4964 2.8576 -0.9133 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9385 -0.4786 -0.7226 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4803 0.1970 -1.7520 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6456 -0.1108 -0.0066 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8388 -1.5899 -3.2668 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2125 -4.7820 0.4107 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2423 -2.3509 0.9152 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7197 4.4447 -0.0223 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1463 -6.4832 -1.3041 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7339 -8.2067 -2.8279 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4799 -7.5729 -5.2779 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2354 -7.6711 -5.5552 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3508 -9.0881 -4.9405 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 24 1 0 0 0 0 1 3 1 0 0 0 0 3 4 1 0 0 0 0 3 33 1 0 0 0 0 4 7 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 5 34 1 0 0 0 0 6 7 2 0 0 0 0 6 8 1 0 0 0 0 6 35 1 0 0 0 0 7 36 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 13 1 0 0 0 0 11 14 1 0 0 0 0 15 23 1 0 0 0 0 15 16 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 38 1 0 0 0 0 16 39 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 18 40 1 0 0 0 0 19 20 2 0 0 0 0 20 21 1 0 0 0 0 20 28 1 0 0 0 0 21 22 2 0 0 0 0 21 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 2 0 0 0 0 23 27 1 0 0 0 0 24 25 1 0 0 0 0 25 26 1 0 0 0 0 26 27 2 0 0 0 0 26 43 1 0 0 0 0 28 29 1 0 0 0 0 28 44 1 0 0 0 0 29 30 1 0 0 0 0 29 31 2 0 0 0 0 30 32 1 0 0 0 0 30 45 1 0 0 0 0 32 46 1 0 0 0 0 32 47 1 0 0 0 0 32 48 1 0 0 0 0 M END > 514493 > Serine/threonine-protein kinase B-raf > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 43 > 2007 > 514493 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 43 > 2007 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 58 62 0 0 0 0 0 0 0 0999 V2000 0.2858 1.9872 -2.0273 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3371 0.8251 -2.6495 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3359 -0.0321 -2.4828 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3814 0.2328 -1.6527 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4003 1.4532 -0.9519 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4476 1.7979 -0.0762 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4053 3.0111 0.5801 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3436 3.8887 0.3845 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3179 3.5773 -0.4578 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3250 2.3551 -1.1432 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7799 2.8462 -2.2441 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5153 0.9229 0.1261 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7996 1.3004 -0.2370 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8519 0.3780 -0.1373 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1352 0.7773 -0.5136 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3145 2.0728 -0.9711 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2288 2.9253 -1.0416 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0240 2.5271 -0.6807 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1843 -2.5545 1.2902 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4110 -1.3355 0.8475 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6053 -0.9957 0.3592 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6173 -1.9537 0.3231 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3328 -3.2307 0.8020 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1147 -3.4875 1.2729 N 0 0 0 0 0 0 0 0 0 0 0 0 8.3042 -4.2194 0.7883 N 0 0 0 0 0 0 0 0 0 0 0 0 9.6415 -3.9251 0.2676 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5214 3.3894 1.5195 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7466 2.5321 -3.2035 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0726 2.8786 -2.9912 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0319 2.5683 -3.9538 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6517 1.9108 -5.1251 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3297 1.5701 -5.3273 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3781 1.8777 -4.3731 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.4031 2.9223 -3.7416 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.5273 3.2126 -3.5676 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3186 -0.9679 -3.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1826 -0.4815 -1.5335 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3316 4.8326 0.9092 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5017 4.2710 -0.5964 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8549 3.6653 -1.7300 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3595 0.0506 0.5207 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9685 0.0932 -0.4494 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2946 2.4139 -1.2699 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3692 3.9350 -1.3983 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2078 -2.7958 1.6834 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5955 -1.7126 -0.0660 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0985 -5.1061 1.1234 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5657 -3.6160 -0.7749 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0908 -3.1226 0.8527 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2632 -4.8177 0.3376 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3280 3.8578 0.9555 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1462 4.0892 2.2663 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8971 2.4948 2.0162 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3611 3.3868 -2.0830 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3922 1.6684 -5.8730 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0377 1.0615 -6.2342 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3450 1.6089 -4.5370 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.5327 3.4722 -3.4120 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 10 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 36 1 0 0 0 0 4 5 1 0 0 0 0 4 37 1 0 0 0 0 5 6 1 0 0 0 0 5 10 2 0 0 0 0 6 7 2 0 0 0 0 6 12 1 0 0 0 0 7 8 1 0 0 0 0 7 27 1 0 0 0 0 8 9 2 0 0 0 0 8 38 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 11 28 1 0 0 0 0 11 40 1 0 0 0 0 12 13 1 0 0 0 0 12 41 1 0 0 0 0 13 14 1 0 0 0 0 13 18 2 0 0 0 0 14 15 2 0 0 0 0 14 21 1 0 0 0 0 15 16 1 0 0 0 0 15 42 1 0 0 0 0 16 17 2 0 0 0 0 16 43 1 0 0 0 0 17 18 1 0 0 0 0 17 44 1 0 0 0 0 19 20 1 0 0 0 0 19 24 2 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 25 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 33 2 0 0 0 0 29 30 2 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 30 34 1 0 0 0 0 31 32 2 0 0 0 0 31 55 1 0 0 0 0 32 33 1 0 0 0 0 32 56 1 0 0 0 0 33 57 1 0 0 0 0 34 35 3 0 0 0 0 35 58 1 0 0 0 0 M END > 674734 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 15 > 2009 > 674734 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 15 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 54 59 0 0 0 0 0 0 0 0999 V2000 0.2837 1.9804 -2.0210 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3413 0.8209 -2.6476 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3442 -0.0319 -2.4832 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3874 0.2349 -1.6507 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3996 1.4527 -0.9453 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4441 1.7992 -0.0669 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3952 3.0096 0.5939 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3295 3.8828 0.4002 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3063 3.5697 -0.4446 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3202 2.3501 -1.1345 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7860 2.8348 -2.2356 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5157 0.9286 0.1334 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5082 3.3897 1.5361 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7508 2.5192 -3.1971 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0821 2.8523 -2.9824 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0321 2.5444 -3.9363 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6587 1.9046 -5.1052 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3332 1.5711 -5.3216 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3789 1.8770 -4.3713 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8556 1.5191 -6.3021 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.7981 1.3128 -0.2283 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8556 0.3947 -0.1299 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1380 0.8018 -0.5051 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3103 2.0990 -0.9597 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2202 2.9461 -1.0288 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0170 2.5413 -0.6693 N 0 0 0 0 0 0 0 0 0 0 0 0 8.9270 -1.9547 -0.0827 N 0 0 0 0 0 0 0 0 0 0 0 0 9.4366 -3.1371 0.1118 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5022 -3.9631 0.6608 N 0 0 0 0 0 0 0 0 0 0 0 0 7.3479 -3.2361 0.8105 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1324 -3.4916 1.2777 N 0 0 0 0 0 0 0 0 0 0 0 0 5.2063 -2.5548 1.2916 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4277 -1.3317 0.8507 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6162 -0.9792 0.3629 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6379 -1.9459 0.3274 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3324 -0.9656 -3.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1920 -0.4759 -1.5332 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3123 4.8247 0.9284 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4870 4.2599 -0.5817 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8655 3.6517 -1.7188 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3638 0.0545 0.5256 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3166 3.8569 0.9738 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1307 4.0911 2.2802 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8822 2.4962 2.0359 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3741 3.3513 -2.0701 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0674 2.8028 -3.7697 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0447 1.0712 -6.2344 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3445 1.6169 -4.5408 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9748 0.1220 -0.4421 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2888 2.4458 -1.2574 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3557 3.9572 -1.3833 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4507 -3.4214 -0.1273 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6295 -4.8942 0.9014 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2277 -2.7978 1.6786 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 10 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 36 1 0 0 0 0 4 5 1 0 0 0 0 4 37 1 0 0 0 0 5 6 1 0 0 0 0 5 10 2 0 0 0 0 6 7 2 0 0 0 0 6 12 1 0 0 0 0 7 8 1 0 0 0 0 7 13 1 0 0 0 0 8 9 2 0 0 0 0 8 38 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 11 14 1 0 0 0 0 11 40 1 0 0 0 0 12 21 1 0 0 0 0 12 41 1 0 0 0 0 13 42 1 0 0 0 0 13 43 1 0 0 0 0 13 44 1 0 0 0 0 14 15 1 0 0 0 0 14 19 2 0 0 0 0 15 16 2 0 0 0 0 15 45 1 0 0 0 0 16 17 1 0 0 0 0 16 46 1 0 0 0 0 17 18 2 0 0 0 0 17 20 1 0 0 0 0 18 19 1 0 0 0 0 18 47 1 0 0 0 0 19 48 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 23 24 1 0 0 0 0 23 49 1 0 0 0 0 24 25 2 0 0 0 0 24 50 1 0 0 0 0 25 26 1 0 0 0 0 25 51 1 0 0 0 0 27 28 2 0 0 0 0 27 35 1 0 0 0 0 28 29 1 0 0 0 0 28 52 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 30 31 2 0 0 0 0 30 35 1 0 0 0 0 31 32 1 0 0 0 0 32 33 2 0 0 0 0 32 54 1 0 0 0 0 33 34 1 0 0 0 0 34 35 2 0 0 0 0 M END > 674704 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 1 > 2009 > 674704 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 1 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 55 58 0 0 0 999 V2000 -0.0119 1.1317 -0.6691 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0913 0.0004 -1.1105 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1326 1.8286 -0.3957 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.3869 1.2859 -0.7018 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6147 -0.0729 -0.5358 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6428 1.5735 -1.4663 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4050 2.1080 -1.1662 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7643 -0.1301 -1.1501 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6379 -0.8988 -0.2535 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7532 -2.3146 -0.7567 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7521 -2.6599 -1.6451 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8626 -3.8965 -2.0917 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0275 -4.8497 -1.7099 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9979 -4.5731 -0.8173 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8596 -3.2866 -0.3273 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5431 1.1396 -0.6564 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3043 1.7350 -0.4290 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5563 3.0320 0.0771 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8467 3.1978 0.1464 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4854 2.0351 -0.2978 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8757 0.2166 -1.2968 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8581 -0.6092 -0.8338 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0654 -1.9443 -0.6682 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.4273 -2.3826 -0.6159 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.1932 -1.7084 -1.7622 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.1065 -0.2902 -1.5860 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.6211 -2.0674 -2.9874 F 0 0 0 0 0 0 0 0 0 0 0 0 -7.5341 -2.1064 -1.7321 F 0 0 0 0 0 0 0 0 0 0 0 0 -5.4817 -3.7725 -0.7654 F 0 0 0 0 0 0 0 0 0 0 0 0 -5.9940 -2.0166 0.6097 F 0 0 0 0 0 0 0 0 0 0 0 0 4.9339 1.8290 -0.3709 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1812 -6.1426 -2.2076 N 0 0 0 0 0 0 0 0 0 0 0 0 5.2403 -6.4440 -2.9848 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3335 -7.6622 -3.5539 N 0 0 0 0 0 0 0 0 0 0 0 0 6.1115 -5.6171 -3.1724 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4848 -7.9898 -4.3986 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0705 2.7061 0.0131 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8232 -0.7128 -0.1748 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4332 2.2146 -1.8277 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2291 3.1661 -1.2924 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1461 -0.0937 -2.0834 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6265 -0.4404 -0.2285 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2141 -0.9035 0.7507 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4518 -1.9080 -1.9790 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3179 -5.3528 -0.5075 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0697 -3.0423 0.3675 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8084 3.7589 0.3572 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3084 1.5307 0.6083 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1534 1.0466 -1.0975 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4179 2.7561 -0.6780 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5260 -6.8254 -1.9946 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6384 -8.3219 -3.4042 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5238 -7.3012 -5.2426 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4009 -7.9012 -3.8147 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3861 -9.0109 -4.7671 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 17 1 0 0 0 0 1 3 1 0 0 0 0 3 4 1 0 0 0 0 3 37 1 0 0 0 0 4 7 1 0 0 0 0 4 5 2 0 0 0 0 5 22 1 0 0 0 0 5 38 1 0 0 0 0 6 21 1 0 0 0 0 6 7 2 0 0 0 0 6 39 1 0 0 0 0 7 40 1 0 0 0 0 8 16 1 0 0 0 0 8 9 1 0 0 0 0 8 41 1 0 0 0 0 9 10 1 0 0 0 0 9 42 1 0 0 0 0 9 43 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 11 44 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 32 1 0 0 0 0 14 15 2 0 0 0 0 14 45 1 0 0 0 0 15 46 1 0 0 0 0 16 20 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 47 1 0 0 0 0 19 20 1 0 0 0 0 20 31 1 0 0 0 0 21 22 2 0 0 0 0 21 26 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 24 25 1 0 0 0 0 24 29 1 0 0 0 0 24 30 1 0 0 0 0 25 26 1 0 0 0 0 25 27 1 0 0 0 0 25 28 1 0 0 0 0 31 48 1 0 0 0 0 31 49 1 0 0 0 0 31 50 1 0 0 0 0 32 33 1 0 0 0 0 32 51 1 0 0 0 0 33 34 1 0 0 0 0 33 35 2 0 0 0 0 34 36 1 0 0 0 0 34 52 1 0 0 0 0 36 53 1 0 0 0 0 36 54 1 0 0 0 0 36 55 1 0 0 0 0 M END > 514487 > Serine/threonine-protein kinase B-raf > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 40 > 2007 > 514487 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 40 > 2007 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 56 60 0 0 0 0 0 0 0 0999 V2000 0.2832 1.9696 -2.0269 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3571 0.8199 -2.6696 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3725 -0.0204 -2.5178 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4127 0.2501 -1.6828 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4077 1.4580 -0.9605 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4481 1.8076 -0.0784 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3822 3.0079 0.5993 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3035 3.8679 0.4189 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2842 3.5517 -0.4294 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3150 2.3420 -1.1360 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7991 2.8111 -2.2288 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5328 0.9502 0.1086 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8084 1.3564 -0.2540 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8784 0.4530 -0.1687 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1526 0.8812 -0.5443 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3056 2.1853 -0.9868 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2037 3.0177 -1.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0079 2.5923 -0.6836 N 0 0 0 0 0 0 0 0 0 0 0 0 5.2719 -2.5273 1.2295 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4739 -1.2990 0.8008 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6596 -0.9310 0.3120 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6892 -1.8693 0.2603 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4306 -3.1571 0.7247 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2195 -3.4424 1.1972 N 0 0 0 0 0 0 0 0 0 0 0 0 8.4202 -4.1272 0.6947 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7495 -3.8018 0.1720 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4906 3.3913 1.5455 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7600 2.4950 -3.1938 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0955 2.8079 -2.9747 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0417 2.4995 -3.9321 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6605 1.8789 -5.1088 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3308 1.5655 -5.3296 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3802 1.8724 -4.3761 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8528 1.4921 -6.3099 Cl 0 0 0 0 0 0 0 0 0 0 0 0 1.3735 -0.9468 -3.0730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2278 -0.4503 -1.5760 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2729 4.8018 0.9605 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4548 4.2317 -0.5563 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8899 3.6196 -1.7005 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3948 0.0701 0.4923 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9989 0.2123 -0.4909 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2781 2.5485 -1.2845 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3238 4.0341 -1.3882 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3017 -2.7916 1.6236 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6610 -1.6052 -0.1297 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2325 -5.0216 1.0199 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6631 -3.4815 -0.8663 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1863 -2.9982 0.7649 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3879 -4.6834 0.2284 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2976 3.8653 0.9868 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1071 4.0876 2.2913 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8688 2.4981 2.0429 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3936 3.2917 -2.0563 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0802 2.7426 -3.7623 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0362 1.0808 -6.2487 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3426 1.6276 -4.5489 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 10 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 35 1 0 0 0 0 4 5 1 0 0 0 0 4 36 1 0 0 0 0 5 6 1 0 0 0 0 5 10 2 0 0 0 0 6 7 2 0 0 0 0 6 12 1 0 0 0 0 7 8 1 0 0 0 0 7 27 1 0 0 0 0 8 9 2 0 0 0 0 8 37 1 0 0 0 0 9 10 1 0 0 0 0 9 38 1 0 0 0 0 11 28 1 0 0 0 0 11 39 1 0 0 0 0 12 13 1 0 0 0 0 12 40 1 0 0 0 0 13 14 1 0 0 0 0 13 18 2 0 0 0 0 14 15 2 0 0 0 0 14 21 1 0 0 0 0 15 16 1 0 0 0 0 15 41 1 0 0 0 0 16 17 2 0 0 0 0 16 42 1 0 0 0 0 17 18 1 0 0 0 0 17 43 1 0 0 0 0 19 20 1 0 0 0 0 19 24 2 0 0 0 0 19 44 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 45 1 0 0 0 0 23 24 1 0 0 0 0 23 25 1 0 0 0 0 25 26 1 0 0 0 0 25 46 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 28 29 1 0 0 0 0 28 33 2 0 0 0 0 29 30 2 0 0 0 0 29 53 1 0 0 0 0 30 31 1 0 0 0 0 30 54 1 0 0 0 0 31 32 2 0 0 0 0 31 34 1 0 0 0 0 32 33 1 0 0 0 0 32 55 1 0 0 0 0 33 56 1 0 0 0 0 M END > 674683 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 13 > 2009 > 674683 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 13 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 54 58 0 0 0 0 0 0 0 0999 V2000 0.2857 1.9726 -2.0285 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3597 0.8224 -2.6703 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3747 -0.0181 -2.5174 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4145 0.2527 -1.6820 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4095 1.4611 -0.9605 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4494 1.8110 -0.0781 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3835 3.0118 0.5987 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3051 3.8720 0.4171 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2860 3.5553 -0.4313 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3171 2.3453 -1.1374 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7963 2.8144 -2.2316 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5337 0.9535 0.1102 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.7563 2.4980 -3.1966 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0922 2.8118 -2.9788 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0373 2.5028 -3.9368 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6556 1.8817 -5.1122 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3271 1.5677 -5.3320 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3764 1.8743 -4.3781 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.4866 2.8424 -3.7013 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7503 4.1261 -4.1907 F 0 0 0 0 0 0 0 0 0 0 0 0 -6.2967 1.9147 -4.3649 F 0 0 0 0 0 0 0 0 0 0 0 0 -5.7581 2.8014 -2.3295 F 0 0 0 0 0 0 0 0 0 0 0 0 5.8096 1.3591 -0.2516 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8794 0.4554 -0.1651 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1542 0.8833 -0.5399 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3077 2.1871 -0.9828 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2060 3.0197 -1.0407 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0098 2.5948 -0.6816 N 0 0 0 0 0 0 0 0 0 0 0 0 5.2788 -2.5255 1.2313 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4762 -1.2959 0.8035 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6601 -0.9280 0.3159 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6923 -1.8705 0.2654 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4357 -3.1484 0.7264 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2312 -3.4361 1.1969 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4915 3.3955 1.5453 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3758 -0.9448 -3.0720 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2293 -0.4479 -1.5742 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2747 4.8065 0.9577 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4568 4.2354 -0.5588 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8872 3.6233 -1.7040 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3952 0.0735 0.4941 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3910 3.2964 -2.0611 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3969 1.6412 -5.8599 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0324 1.0824 -6.2507 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3389 1.6286 -4.5504 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0004 0.2143 -0.4857 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2805 2.5500 -1.2800 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3265 4.0359 -1.3860 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3100 -2.7944 1.6258 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6646 -1.6070 -0.1240 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2079 -3.9031 0.7030 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2986 3.8696 0.9869 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1076 4.0919 2.2908 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8696 2.5025 2.0430 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 10 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 36 1 0 0 0 0 4 5 1 0 0 0 0 4 37 1 0 0 0 0 5 6 1 0 0 0 0 5 10 2 0 0 0 0 6 7 2 0 0 0 0 6 12 1 0 0 0 0 7 8 1 0 0 0 0 7 35 1 0 0 0 0 8 9 2 0 0 0 0 8 38 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 11 13 1 0 0 0 0 11 40 1 0 0 0 0 12 23 1 0 0 0 0 12 41 1 0 0 0 0 13 14 1 0 0 0 0 13 18 2 0 0 0 0 14 15 2 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 15 19 1 0 0 0 0 16 17 2 0 0 0 0 16 43 1 0 0 0 0 17 18 1 0 0 0 0 17 44 1 0 0 0 0 18 45 1 0 0 0 0 19 20 1 0 0 0 0 19 21 1 0 0 0 0 19 22 1 0 0 0 0 23 24 1 0 0 0 0 23 28 2 0 0 0 0 24 25 2 0 0 0 0 24 31 1 0 0 0 0 25 26 1 0 0 0 0 25 46 1 0 0 0 0 26 27 2 0 0 0 0 26 47 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 29 30 1 0 0 0 0 29 34 2 0 0 0 0 29 49 1 0 0 0 0 30 31 2 0 0 0 0 31 32 1 0 0 0 0 32 33 2 0 0 0 0 32 50 1 0 0 0 0 33 34 1 0 0 0 0 33 51 1 0 0 0 0 35 52 1 0 0 0 0 35 53 1 0 0 0 0 35 54 1 0 0 0 0 M END > 674645 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 12a > 2009 > 674645 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 12a > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 53 55 0 0 0 999 V2000 -0.5824 0.4972 -0.3208 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5640 -0.5981 -0.8508 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7584 1.0648 0.0129 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.9623 0.4343 -0.3283 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0628 -0.9494 -0.2674 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2430 0.5731 -1.0569 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0564 1.1938 -0.7216 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2910 -0.4633 -0.9141 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2436 -1.2160 -0.0871 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4782 -2.5727 -0.6999 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6793 -3.6432 -0.3510 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8727 -4.8341 -0.8850 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8323 -5.0503 -1.7706 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6743 -4.0177 -2.1682 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4963 -2.7576 -1.6257 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9613 0.7379 -0.3195 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6764 1.1975 -0.0393 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8156 2.4680 0.5674 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0863 2.7454 0.6434 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8226 1.6848 0.1047 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.3453 -0.8111 -0.9920 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2504 -1.5706 -0.5984 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2829 1.6185 0.0084 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0006 -6.3249 -2.3092 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1215 -7.3028 -2.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3427 -8.5606 -2.4444 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1290 -7.0504 -1.3584 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3872 -9.6236 -2.1232 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.8614 -1.6034 -1.4141 S 0 0 0 0 0 0 0 0 0 0 0 0 -7.9426 -0.2122 -1.8456 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3881 0.4940 -2.9184 F 0 0 0 0 0 0 0 0 0 0 0 0 -9.2039 -0.6968 -2.2083 F 0 0 0 0 0 0 0 0 0 0 0 0 -8.0696 0.6392 -0.7427 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.7714 1.9097 0.4892 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2117 -1.5397 0.0386 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0940 1.1638 -1.3622 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9791 2.2701 -0.7648 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6549 -0.3186 -1.8439 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1872 -0.6730 -0.0344 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8370 -1.3364 0.9171 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8861 -3.5042 0.3687 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4570 -4.1971 -2.8904 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1322 -1.9353 -1.9188 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0081 3.0991 0.9082 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3294 -2.6465 -0.5482 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6948 1.2809 0.9595 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5637 0.9182 -0.7782 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6767 2.6071 -0.2276 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7504 -6.5080 -2.8967 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1346 -8.7620 -2.9672 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3080 -9.7260 -1.0409 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4107 -9.3715 -2.5367 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7319 -10.5641 -2.5529 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 17 1 0 0 0 0 1 3 1 0 0 0 0 3 4 1 0 0 0 0 3 34 1 0 0 0 0 4 7 1 0 0 0 0 4 5 2 0 0 0 0 5 22 1 0 0 0 0 5 35 1 0 0 0 0 6 7 2 0 0 0 0 6 21 1 0 0 0 0 6 36 1 0 0 0 0 7 37 1 0 0 0 0 8 16 1 0 0 0 0 8 9 1 0 0 0 0 8 38 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 9 40 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 11 41 1 0 0 0 0 12 13 2 0 0 0 0 13 24 1 0 0 0 0 13 14 1 0 0 0 0 14 15 2 0 0 0 0 14 42 1 0 0 0 0 15 43 1 0 0 0 0 16 17 2 0 0 0 0 16 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 44 1 0 0 0 0 19 20 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 29 1 0 0 0 0 22 45 1 0 0 0 0 23 46 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 28 1 0 0 0 0 26 50 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 30 31 1 0 0 0 0 30 32 1 0 0 0 0 30 33 1 0 0 0 0 M END > 514488 > Serine/threonine-protein kinase B-raf > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 41 > 2007 > 514488 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 41 > 2007 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 51 54 0 0 0 999 V2000 -0.0387 1.2705 -0.2278 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0234 0.0714 -0.4415 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.2088 1.8995 -0.0002 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4143 1.1945 -0.1032 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4793 -0.1321 0.3001 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7368 1.1301 -0.7049 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5464 1.8242 -0.6035 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8070 -0.1928 -0.2990 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6733 -0.8271 0.2033 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0003 -2.1117 0.5294 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.2371 -2.3800 -0.1572 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.8447 -1.0811 -0.2874 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.9895 -2.9354 -1.4172 F 0 0 0 0 0 0 0 0 0 0 0 0 -6.0483 -3.2280 0.6044 F 0 0 0 0 0 0 0 0 0 0 0 0 2.6771 0.1489 -0.6820 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0488 -0.3194 -0.8945 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0381 -1.8037 -1.1552 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9225 -2.2846 -2.4442 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9125 -3.5820 -2.6839 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0121 -4.4693 -1.7068 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1315 -4.0559 -0.3846 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1502 -2.7016 -0.1022 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4341 1.4911 -0.4223 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1727 2.0022 -0.2127 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3399 3.7321 0.0772 S 0 0 0 0 0 0 0 0 0 0 0 0 3.0349 3.6136 -0.1041 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3871 2.3939 -0.3476 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9967 -5.8306 -2.0060 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7740 -6.2402 -3.2706 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6575 -7.5551 -3.5424 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6782 -5.4235 -4.1661 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4154 -8.0003 -4.9170 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3247 -9.5272 -4.9500 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2158 2.8406 0.2350 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5990 -0.6223 0.6889 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6161 1.6220 -1.0936 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4964 2.8576 -0.9133 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9385 -0.4786 -0.7226 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4803 0.1970 -1.7520 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6456 -0.1108 -0.0066 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8388 -1.5899 -3.2668 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2125 -4.7820 0.4107 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2423 -2.3509 0.9152 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7197 4.4447 -0.0223 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1463 -6.4832 -1.3041 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7339 -8.2067 -2.8279 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4799 -7.5729 -5.2779 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2354 -7.6711 -5.5552 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5047 -9.8564 -4.3117 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1446 -9.8585 -5.9727 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2602 -9.9546 -4.5891 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 24 1 0 0 0 0 1 3 1 0 0 0 0 3 4 1 0 0 0 0 3 34 1 0 0 0 0 4 7 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 5 35 1 0 0 0 0 6 7 2 0 0 0 0 6 8 1 0 0 0 0 6 36 1 0 0 0 0 7 37 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 13 1 0 0 0 0 11 14 1 0 0 0 0 15 23 1 0 0 0 0 15 16 1 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 16 39 1 0 0 0 0 16 40 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 20 21 1 0 0 0 0 20 28 1 0 0 0 0 21 22 2 0 0 0 0 21 42 1 0 0 0 0 22 43 1 0 0 0 0 23 24 2 0 0 0 0 23 27 1 0 0 0 0 24 25 1 0 0 0 0 25 26 1 0 0 0 0 26 27 2 0 0 0 0 26 44 1 0 0 0 0 28 29 1 0 0 0 0 28 45 1 0 0 0 0 29 30 1 0 0 0 0 29 31 2 0 0 0 0 30 32 1 0 0 0 0 30 46 1 0 0 0 0 32 33 1 0 0 0 0 32 47 1 0 0 0 0 32 48 1 0 0 0 0 33 49 1 0 0 0 0 33 50 1 0 0 0 0 33 51 1 0 0 0 0 M END > 514489 > Serine/threonine-protein kinase B-raf > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 42 > 2007 > 514489 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574417 > Bioorg. Med. Chem. Lett.|2007|17|15|4378 > 42 > 2007 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 54 0 0 0 0 0 0 0 0999 V2000 0.1257 1.4933 1.4982 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0092 0.1983 0.7948 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0907 -0.6824 0.7662 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9738 -1.8950 0.1045 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2184 -2.2296 -0.5278 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2895 -1.3568 -0.4998 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1853 -0.1498 0.1617 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1652 1.7922 2.0530 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9187 2.3448 1.5196 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.8423 3.5265 2.2637 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5226 4.6611 1.8400 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4497 5.8246 2.5800 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7005 5.8611 3.7420 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0218 4.7337 4.1663 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0909 3.5665 3.4309 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1869 7.0561 2.1208 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4728 7.0625 2.6720 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.4945 8.1974 2.5394 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.2780 7.0517 0.7248 F 0 0 0 0 0 0 0 0 0 0 0 0 2.0547 -2.7810 0.0725 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3497 -2.2921 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4269 -3.1854 -0.1155 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7215 -2.6714 -0.2074 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8866 -1.2958 -0.1942 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7766 -0.4787 -0.0917 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5616 -0.9857 -0.0059 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7478 -6.4370 -0.1935 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9568 -5.1369 -0.1849 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1946 -4.6480 -0.1245 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2710 -5.5395 -0.0702 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0001 -6.8951 -0.0817 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7409 -7.3022 -0.1433 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3429 -3.5484 -1.2464 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0160 -0.4203 1.2577 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2129 -1.6221 -0.9930 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0246 0.5295 0.1812 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7234 2.1382 1.0189 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1075 4.6334 0.9325 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6451 6.7723 4.3190 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5627 4.7655 5.0739 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4397 2.6862 3.7626 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8989 -3.7376 0.1108 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5738 -3.3300 -0.2864 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8747 -0.8655 -0.2633 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9061 0.5934 -0.0811 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7334 -6.8048 -0.2385 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2875 -5.1781 -0.0208 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8054 -7.6136 -0.0413 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7085 -4.3065 -0.5539 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0430 -3.4457 -2.0755 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6329 -3.8468 -1.6298 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 8 2 0 0 0 0 1 9 1 0 0 0 0 2 3 1 0 0 0 0 2 7 2 0 0 0 0 3 4 2 0 0 0 0 3 34 1 0 0 0 0 4 5 1 0 0 0 0 4 20 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 35 1 0 0 0 0 7 36 1 0 0 0 0 9 10 1 0 0 0 0 9 37 1 0 0 0 0 10 11 1 0 0 0 0 10 15 2 0 0 0 0 11 12 2 0 0 0 0 11 38 1 0 0 0 0 12 13 1 0 0 0 0 12 16 1 0 0 0 0 13 14 2 0 0 0 0 13 39 1 0 0 0 0 14 15 1 0 0 0 0 14 40 1 0 0 0 0 15 41 1 0 0 0 0 16 17 1 0 0 0 0 16 18 1 0 0 0 0 16 19 1 0 0 0 0 20 21 1 0 0 0 0 20 42 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 22 29 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 24 25 2 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 27 28 1 0 0 0 0 27 32 2 0 0 0 0 27 46 1 0 0 0 0 28 29 2 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 47 1 0 0 0 0 31 32 1 0 0 0 0 31 48 1 0 0 0 0 33 49 1 0 0 0 0 33 50 1 0 0 0 0 33 51 1 0 0 0 0 M END > 466520 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 2 > 2009 > 466520 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 2 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 54 0 0 0 0 0 0 0 0999 V2000 -0.0181 1.4737 0.0146 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0015 -0.0045 0.0115 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2169 -0.6872 0.0008 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2266 -2.0781 -0.0015 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0223 -2.7817 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1793 -2.1010 0.0173 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1973 -0.7205 0.0251 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0264 2.0955 0.0079 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1942 2.1320 0.0193 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2149 3.5258 0.1325 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1831 4.2641 -0.5361 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2042 5.6397 -0.4177 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2629 6.2824 0.3657 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2979 5.5505 1.0326 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2712 4.1742 0.9183 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2539 6.4416 -1.1431 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3783 6.5875 -0.3237 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.7404 7.7039 -1.4595 F 0 0 0 0 0 0 0 0 0 0 0 0 -3.6173 5.7778 -2.3197 F 0 0 0 0 0 0 0 0 0 0 0 0 6.0860 -4.8682 -0.0212 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0100 -4.5494 -0.9067 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8396 -3.5832 -1.8070 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7256 -2.8840 -1.8642 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7005 -3.1777 -0.9448 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4866 -2.4788 -0.9411 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5159 -2.8120 -0.0133 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7411 -3.8387 0.9173 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9131 -4.5273 0.9288 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9183 -4.2140 0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2045 -5.2467 -0.8997 N 0 0 0 0 0 0 0 0 0 0 0 0 9.2510 -4.9167 -1.8703 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0323 -4.2887 0.0037 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1471 -0.1385 -0.0059 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1088 -2.6508 0.0236 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1399 -0.1935 0.0336 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0262 1.6391 -0.0559 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9182 3.7629 -1.1483 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2814 7.3585 0.4564 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4357 6.0554 1.6435 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4828 3.6030 1.4395 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6009 -2.1027 -2.5994 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3103 -1.6880 -1.6551 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9722 -4.0847 1.6347 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0709 -5.3142 1.6516 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3493 -5.9542 -0.2521 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1115 -5.5667 -1.7119 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8680 -5.0607 -2.8806 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5522 -3.8772 -1.7406 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0430 -4.6540 1.0305 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8593 -4.6569 -0.5038 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9206 -4.6450 -0.5180 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 8 2 0 0 0 0 1 9 1 0 0 0 0 2 3 1 0 0 0 0 2 7 2 0 0 0 0 3 4 2 0 0 0 0 3 33 1 0 0 0 0 4 5 1 0 0 0 0 4 26 1 0 0 0 0 5 6 2 0 0 0 0 5 32 1 0 0 0 0 6 7 1 0 0 0 0 6 34 1 0 0 0 0 7 35 1 0 0 0 0 9 10 1 0 0 0 0 9 36 1 0 0 0 0 10 11 1 0 0 0 0 10 15 2 0 0 0 0 11 12 2 0 0 0 0 11 37 1 0 0 0 0 12 13 1 0 0 0 0 12 16 1 0 0 0 0 13 14 2 0 0 0 0 13 38 1 0 0 0 0 14 15 1 0 0 0 0 14 39 1 0 0 0 0 15 40 1 0 0 0 0 16 17 1 0 0 0 0 16 18 1 0 0 0 0 16 19 1 0 0 0 0 20 21 1 0 0 0 0 20 29 2 0 0 0 0 21 22 2 0 0 0 0 21 30 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 29 1 0 0 0 0 25 26 2 0 0 0 0 25 42 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 43 1 0 0 0 0 28 29 1 0 0 0 0 28 44 1 0 0 0 0 30 31 1 0 0 0 0 30 45 1 0 0 0 0 31 46 1 0 0 0 0 31 47 1 0 0 0 0 31 48 1 0 0 0 0 32 49 1 0 0 0 0 32 50 1 0 0 0 0 32 51 1 0 0 0 0 M END > 458459 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 3 > 2009 > 458459 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 3 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 75 0 0 0 0 0 0 0 0999 V2000 -0.0429 1.2727 0.2548 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5502 0.8489 1.3414 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7838 0.1798 1.2933 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3973 -0.0415 0.0509 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4906 1.0930 -0.9629 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7325 0.4275 -1.1067 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2863 0.2419 -2.3823 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6309 0.7015 -3.4816 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3988 1.3633 -3.3553 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1711 1.5591 -2.1070 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4093 -0.2717 2.4997 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9056 -0.6299 3.4567 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6090 -0.6949 -0.0390 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6443 -2.0769 -0.2559 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4601 -2.7991 -0.3266 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4940 -4.1619 -0.5462 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7125 -4.8111 -0.6961 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8984 -4.0884 -0.6254 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8639 -2.7254 -0.4061 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7557 -6.5503 -0.9752 S 0 0 0 0 0 0 0 0 0 0 0 0 4.0466 -6.5742 -2.7129 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2737 -5.5247 -3.4680 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4504 -5.9219 -4.7389 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3310 -7.2600 -4.7845 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0799 -7.6846 -3.4996 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8771 -9.0683 -3.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4219 -4.8994 -0.8127 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -0.2965 1.8536 -4.5631 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2439 1.6692 -5.7602 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4654 2.1694 -6.9923 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4725 3.0813 -7.7858 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2189 3.5688 -8.9867 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5569 4.6276 -9.6477 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1563 5.0517 -10.9338 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5106 5.5203 -10.6081 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.2863 4.4616 -9.9471 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5731 4.0375 -8.6610 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2019 6.0078 -11.8090 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6772 6.2512 -11.4847 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0796 1.0182 2.2986 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2334 -0.2657 -2.4911 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0623 0.5564 -4.4611 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1196 2.0676 -2.0167 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4365 -0.1963 0.0481 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5123 -2.2946 -0.2093 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5729 -4.7230 -0.6011 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7846 -2.1636 -0.3518 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6532 -5.2763 -5.5806 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4198 -7.8836 -5.6617 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8365 -9.5073 -2.7895 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2115 -9.0831 -2.2000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4323 -9.6439 -3.8748 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2448 2.3622 -4.4712 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1922 1.1606 -5.8521 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7585 1.3219 -7.6120 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3534 2.7289 -6.6983 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7656 3.9287 -7.1661 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3606 2.5218 -8.0797 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6440 5.4851 -8.9805 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5512 4.2524 -9.8901 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4023 5.8570 -11.4107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2193 4.2009 -11.6122 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2806 4.8367 -9.7047 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3735 3.6041 -10.6143 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1317 3.2321 -8.1841 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5102 4.8882 -7.9826 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7438 6.9403 -12.1386 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1221 5.2637 -12.6015 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1354 5.3187 -11.1551 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7571 6.9953 -10.6922 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1902 6.6130 -12.3758 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 2 3 1 0 0 0 0 2 40 1 0 0 0 0 3 11 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 4 13 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 41 1 0 0 0 0 8 9 2 0 0 0 0 8 42 1 0 0 0 0 9 10 1 0 0 0 0 9 28 1 0 0 0 0 10 43 1 0 0 0 0 11 12 3 0 0 0 0 13 14 1 0 0 0 0 13 44 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 45 1 0 0 0 0 16 17 2 0 0 0 0 16 46 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 27 1 0 0 0 0 19 47 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 25 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 26 52 1 0 0 0 0 28 29 2 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 37 1 0 0 0 0 33 34 1 0 0 0 0 33 59 1 0 0 0 0 33 60 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 38 1 0 0 0 0 36 37 1 0 0 0 0 36 63 1 0 0 0 0 36 64 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 39 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 M END > 614299 > Serine/threonine-protein kinase B-raf > Homo sapiens > 18815050 > Bioorg. Med. Chem.|2008|16|20|9202 > 5m > 2008 > 614299 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18815050 > Bioorg. Med. Chem.|2008|16|20|9202 > 5m > 2008 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 61 66 0 0 0 0 0 0 0 0999 V2000 -0.0310 0.8997 -1.1119 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4156 0.0631 -2.0291 N 0 0 0 0 0 0 0 0 0 0 0 0 1.6771 -0.3457 -2.0709 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6007 0.0741 -1.1637 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2023 0.9684 -0.1525 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1004 1.4470 0.8207 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6451 2.3229 1.7850 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3157 2.7327 1.8025 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4272 2.2830 0.8714 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8515 1.3932 -0.1245 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3582 1.2972 -1.1201 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4349 1.0399 0.8105 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.9945 -1.4366 -4.8937 S 0 0 0 0 0 0 0 0 0 0 0 0 -4.0113 -2.7839 -4.5335 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0888 -2.4824 -3.6997 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.0344 -1.2127 -3.2539 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0448 -0.4217 -3.8120 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.1551 0.9252 -3.4736 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2692 1.4909 -2.5861 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2572 0.7163 -2.0221 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1351 -0.6177 -2.3466 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2056 -4.1571 -5.1230 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4412 1.9679 0.5874 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7691 1.5368 0.4495 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7652 2.4871 0.2197 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3972 3.8204 0.1375 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0678 4.1691 0.2837 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1422 3.2543 0.5004 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4458 -2.0921 0.8298 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1521 -0.8117 0.7429 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1083 0.0980 0.5467 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4312 -0.3265 0.4341 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6958 -1.6909 0.5323 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6836 -2.5326 0.7285 N 0 0 0 0 0 0 0 0 0 0 0 0 9.9940 -2.1647 0.4267 N 0 0 0 0 0 0 0 0 0 0 0 0 11.1001 -1.2288 0.2103 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5984 2.8408 2.8309 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9800 -1.0322 -2.8477 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6218 -0.2733 -1.2185 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9818 3.4187 2.5669 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6011 2.6117 0.9013 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6644 1.9780 -0.5007 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6588 0.1080 0.9594 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9386 1.5273 -3.9095 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3576 2.5356 -2.3268 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3476 -1.2093 -1.9037 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0586 -4.1439 -5.8014 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3095 -4.4471 -5.6716 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3892 -4.8736 -4.3223 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7977 2.1905 0.1091 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1433 4.5811 -0.0391 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7818 5.2086 0.2195 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6488 -2.8023 0.9935 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2296 0.3830 0.2746 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1702 -3.1161 0.4962 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9407 -0.6874 -0.7223 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1445 -0.5212 1.0381 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0379 -1.7814 0.1539 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1528 3.6889 2.4292 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0366 3.1574 3.7097 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2953 2.0507 3.1105 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 10 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 5 1 0 0 0 0 4 39 1 0 0 0 0 5 6 1 0 0 0 0 5 10 2 0 0 0 0 6 7 2 0 0 0 0 6 12 1 0 0 0 0 7 8 1 0 0 0 0 7 37 1 0 0 0 0 8 9 2 0 0 0 0 8 40 1 0 0 0 0 9 10 1 0 0 0 0 9 41 1 0 0 0 0 11 20 1 0 0 0 0 11 42 1 0 0 0 0 12 23 1 0 0 0 0 12 43 1 0 0 0 0 13 14 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 22 1 0 0 0 0 15 16 1 0 0 0 0 16 17 1 0 0 0 0 16 21 2 0 0 0 0 17 18 2 0 0 0 0 18 19 1 0 0 0 0 18 44 1 0 0 0 0 19 20 2 0 0 0 0 19 45 1 0 0 0 0 20 21 1 0 0 0 0 21 46 1 0 0 0 0 22 47 1 0 0 0 0 22 48 1 0 0 0 0 22 49 1 0 0 0 0 23 24 1 0 0 0 0 23 28 2 0 0 0 0 24 25 2 0 0 0 0 24 31 1 0 0 0 0 25 26 1 0 0 0 0 25 50 1 0 0 0 0 26 27 2 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 29 30 1 0 0 0 0 29 34 2 0 0 0 0 29 53 1 0 0 0 0 30 31 2 0 0 0 0 31 32 1 0 0 0 0 32 33 2 0 0 0 0 32 54 1 0 0 0 0 33 34 1 0 0 0 0 33 35 1 0 0 0 0 35 36 1 0 0 0 0 35 55 1 0 0 0 0 36 56 1 0 0 0 0 36 57 1 0 0 0 0 36 58 1 0 0 0 0 37 59 1 0 0 0 0 37 60 1 0 0 0 0 37 61 1 0 0 0 0 M END > 674646 > Serine/threonine-protein kinase B-raf > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 16 > 2009 > 674646 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19764794 > J. Med. Chem.|2009|52|20|6189 > 16 > 2009 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 48 50 0 0 0 0 0 0 0 0999 V2000 -0.0239 0.6192 -1.4852 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4265 0.6217 -0.9341 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5781 1.1949 -0.5808 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9389 -1.9453 -4.4386 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7112 -1.9776 -3.1744 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3447 1.7348 -0.5202 N 0 0 0 0 0 0 0 0 0 0 0 0 10.2414 -1.2871 -2.0620 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2292 0.0678 -2.7292 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6089 1.7973 0.0445 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0068 1.1721 -0.7511 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8427 -2.6700 -3.1121 N 0 0 0 0 0 0 0 0 0 0 0 0 10.9791 -1.3277 -0.8816 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2981 1.1746 -1.2621 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7609 0.1642 -1.1995 O 0 0 0 0 0 0 0 0 0 0 0 0 8.9002 -1.3176 -4.5002 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5551 -0.6681 0.2263 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5149 0.0686 -3.2404 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3885 -2.6120 -5.5202 N 0 0 0 0 0 0 0 0 0 0 0 0 6.8623 1.1726 0.0902 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3389 -0.0619 0.1820 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5612 -2.7268 -2.0108 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5493 0.6208 -2.5103 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0688 -0.6266 -3.6495 Cl 0 0 0 0 0 0 0 0 0 0 0 0 12.1621 -2.0618 -0.8656 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0150 1.9367 0.2141 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9517 -0.2110 0.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2499 1.3205 0.2596 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1871 -0.8262 0.0631 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6249 -2.5801 -6.7700 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4310 1.2278 0.3268 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.2654 1.3347 -1.7972 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.8852 -0.6950 -0.8202 F 0 0 0 0 0 0 0 0 0 0 0 0 3.1822 2.5116 0.0375 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3188 -0.7280 -2.1131 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4831 2.6634 0.4628 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8087 1.6025 0.2194 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7098 -0.3626 -4.2112 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2176 -3.1131 -5.4710 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4755 -3.3014 -2.0011 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5527 0.6215 -2.9099 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7594 -2.1150 0.0326 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9458 3.0128 0.2745 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0551 -0.8061 -0.0744 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1465 1.9147 0.3559 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2570 -1.9022 0.0027 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6313 -2.9945 -6.5995 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5348 -1.5499 -7.1145 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1407 -3.1722 -7.5261 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 10 2 0 0 0 0 1 2 1 0 0 0 0 2 30 1 0 0 0 0 2 31 1 0 0 0 0 2 32 1 0 0 0 0 3 9 1 0 0 0 0 3 14 2 0 0 0 0 3 6 1 0 0 0 0 4 5 1 0 0 0 0 4 15 2 0 0 0 0 4 18 1 0 0 0 0 5 7 1 0 0 0 0 5 11 2 0 0 0 0 6 13 1 0 0 0 0 6 33 1 0 0 0 0 7 12 2 0 0 0 0 7 34 1 0 0 0 0 8 17 2 0 0 0 0 8 23 1 0 0 0 0 9 19 1 0 0 0 0 9 35 1 0 0 0 0 10 13 1 0 0 0 0 10 36 1 0 0 0 0 11 21 1 0 0 0 0 12 16 1 0 0 0 0 12 24 1 0 0 0 0 13 22 2 0 0 0 0 16 20 1 0 0 0 0 17 22 1 0 0 0 0 17 37 1 0 0 0 0 18 29 1 0 0 0 0 18 38 1 0 0 0 0 19 25 2 0 0 0 0 19 26 1 0 0 0 0 20 28 1 0 0 0 0 20 27 2 0 0 0 0 21 24 2 0 0 0 0 21 39 1 0 0 0 0 22 40 1 0 0 0 0 24 41 1 0 0 0 0 25 27 1 0 0 0 0 25 42 1 0 0 0 0 26 28 2 0 0 0 0 26 43 1 0 0 0 0 27 44 1 0 0 0 0 28 45 1 0 0 0 0 29 46 1 0 0 0 0 29 47 1 0 0 0 0 29 48 1 0 0 0 0 M END > 376734 > Serine/threonine-protein kinase B-raf > Homo sapiens > 17850214 > Biochem. J.|2007|408|3|297 > BAY 439006 > 2007 > 376734 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18077425 > Proc. Natl. Acad. Sci. U.S.A.|2007|104|50|19936 > "10, sorafenib" > 2007 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 62 66 0 0 0 0 0 0 0 0999 V2000 -2.6139 1.7426 3.3797 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3009 1.6685 4.7255 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2137 2.8184 5.4858 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8426 2.9728 2.7835 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7565 4.1346 3.5432 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4407 4.0554 4.8995 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4276 5.3602 5.3870 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.7220 6.1957 4.3732 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9260 5.4868 3.2468 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.7934 7.4073 4.4616 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.1496 3.0436 1.4610 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.2258 1.8817 0.7608 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3448 1.0723 0.8798 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4218 -0.1111 0.1587 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3779 -0.4807 -0.6795 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2638 0.3284 -0.7952 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1853 1.5070 -0.0787 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.5496 -0.9310 0.2765 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.7610 -0.3831 0.4972 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.8314 -1.1755 0.7043 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.8882 0.8261 0.5094 O 0 0 0 0 0 0 0 0 0 0 0 0 -9.0849 -0.6085 0.9327 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.2454 -1.2835 1.1555 N 0 0 0 0 0 0 0 0 0 0 0 0 -11.2625 -0.3373 1.3361 N 0 0 0 0 0 0 0 0 0 0 0 0 -10.7398 0.8575 1.2273 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.3709 0.7214 0.9794 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.4866 2.1603 1.3541 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.3961 -2.6763 1.1969 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.3064 -3.2518 2.0732 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.4567 -4.6243 2.1076 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.7014 -5.4252 1.2708 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7937 -4.8550 0.3972 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.6395 -3.4830 0.3575 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.6782 2.7755 -0.0336 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.8536 1.9046 1.9918 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.6860 3.1236 2.2328 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6758 0.8394 2.7909 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1242 0.7067 5.1839 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9694 2.7548 6.5358 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2384 5.6223 6.3016 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1521 5.8538 2.3778 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1550 1.3618 1.5326 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4368 -1.4014 -1.2410 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4530 0.0390 -1.4473 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3156 2.1399 -0.1752 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4595 -1.8937 0.1994 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.7299 -2.1401 0.6946 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.6664 1.5284 0.8418 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.8960 -2.6268 2.7275 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.1646 -5.0725 2.7890 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.8205 -6.4982 1.2997 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.2047 -5.4831 -0.2547 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.9304 -3.0383 -0.3250 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.2485 2.0892 -0.6597 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.2184 3.7178 0.0581 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.7043 2.9576 -0.4880 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.7171 1.4663 2.9804 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.3938 2.8469 2.0835 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.4239 1.2183 1.3658 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.7121 3.3057 1.7785 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.2262 4.0659 2.3245 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.5495 2.6853 3.2215 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 37 1 0 0 0 0 2 3 1 0 0 0 0 2 38 1 0 0 0 0 3 6 2 0 0 0 0 3 39 1 0 0 0 0 4 11 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 40 1 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 41 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 42 1 0 0 0 0 14 18 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 43 1 0 0 0 0 16 17 2 0 0 0 0 16 44 1 0 0 0 0 17 45 1 0 0 0 0 18 19 1 0 0 0 0 18 46 1 0 0 0 0 19 20 1 0 0 0 0 19 21 2 0 0 0 0 20 22 1 0 0 0 0 20 47 1 0 0 0 0 22 23 1 0 0 0 0 22 26 2 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 2 0 0 0 0 25 26 1 0 0 0 0 25 27 1 0 0 0 0 26 48 1 0 0 0 0 27 34 1 0 0 0 0 27 35 1 0 0 0 0 27 36 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 29 49 1 0 0 0 0 30 31 2 0 0 0 0 30 50 1 0 0 0 0 31 32 1 0 0 0 0 31 51 1 0 0 0 0 32 33 2 0 0 0 0 32 52 1 0 0 0 0 33 53 1 0 0 0 0 34 54 1 0 0 0 0 34 55 1 0 0 0 0 34 56 1 0 0 0 0 35 57 1 0 0 0 0 35 58 1 0 0 0 0 35 59 1 0 0 0 0 36 60 1 0 0 0 0 36 61 1 0 0 0 0 36 62 1 0 0 0 0 M END > 696369 > Serine/threonine-protein kinase B-raf > Homo sapiens > 20148563 > J. Med. Chem.|2010|53|5|1964 > 27 > 2010 > 696369 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 20148563 > J. Med. Chem.|2010|53|5|1964 > 27 > 2010 $$$$ Wcorina 11010612243D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 60 64 0 0 0 0 0 0 0 0999 V2000 -1.0081 -0.3824 -2.3426 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3933 -0.6637 -3.5500 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6718 -1.5416 -3.6025 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5593 -0.9802 -1.1755 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5126 -1.8652 -1.2213 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1296 -2.1459 -2.4404 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1542 -3.0511 -2.1745 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1607 -3.3096 -0.8532 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1818 -2.6092 -0.2499 N 0 0 0 0 0 0 0 0 0 0 0 0 2.9337 -4.0620 -0.2899 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1644 -0.7023 0.0098 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2737 0.0824 -0.0088 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5244 -0.4909 -0.1654 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6612 0.3182 -0.1781 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5297 1.7002 -0.0328 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2784 2.2611 0.1227 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1530 1.4585 0.1351 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9999 -0.2861 -0.3453 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.0962 0.4977 -0.3572 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.1118 -1.4899 -0.4720 O 0 0 0 0 0 0 0 0 0 0 0 0 -8.3581 -0.0719 -0.5148 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.6307 -1.3973 -0.6659 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.0154 -1.5389 -0.7918 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.5623 -0.3520 -0.7205 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.5450 0.5940 -0.5400 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.7176 1.9794 -0.4172 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.7542 -2.8390 -0.9787 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.7921 -3.5994 0.3485 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.1836 -2.5512 -1.4425 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.0372 -3.6863 -2.0316 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.7181 2.6220 -1.1340 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.8857 3.9875 -1.0108 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.0580 4.7145 -0.1750 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.0604 4.0774 0.5398 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.8921 2.7112 0.4260 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8374 0.3086 -2.3090 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7482 -0.1947 -4.4558 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1477 -1.7577 -4.5476 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7601 -3.4309 -2.8299 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9770 -2.6201 0.6982 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6197 -1.5608 -0.2777 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4068 2.3303 -0.0424 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1781 3.3306 0.2346 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1764 1.9031 0.2574 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0069 1.4582 -0.2561 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.9054 -2.1973 -0.6857 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.3030 -2.9957 1.0986 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.3265 -4.5397 0.2133 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.7738 -3.8044 0.6789 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.1566 -2.0095 -2.3880 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.7179 -3.4916 -1.5777 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.6944 -1.9476 -0.6924 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.0189 -3.8913 -1.7012 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.5716 -4.6266 -2.1668 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.0102 -3.1446 -2.9771 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.3644 2.0549 -1.7875 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.6637 4.4879 -1.5681 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.1908 5.7821 -0.0806 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.4151 4.6479 1.1913 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1128 2.2141 0.9845 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 36 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 6 2 0 0 0 0 3 38 1 0 0 0 0 4 11 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 39 1 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 40 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 41 1 0 0 0 0 14 18 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 42 1 0 0 0 0 16 17 2 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 1 0 0 0 0 18 20 2 0 0 0 0 19 21 1 0 0 0 0 19 45 1 0 0 0 0 21 22 2 0 0 0 0 21 25 1 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 23 24 2 0 0 0 0 23 27 1 0 0 0 0 24 25 1 0 0 0 0 25 26 1 0 0 0 0 26 31 2 0 0 0 0 26 35 1 0 0 0 0 27 28 1 0 0 0 0 27 29 1 0 0 0 0 27 30 1 0 0 0 0 28 47 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 30 55 1 0 0 0 0 31 32 1 0 0 0 0 31 56 1 0 0 0 0 32 33 2 0 0 0 0 32 57 1 0 0 0 0 33 34 1 0 0 0 0 33 58 1 0 0 0 0 34 35 2 0 0 0 0 34 59 1 0 0 0 0 35 60 1 0 0 0 0 M END > 697114 > Serine/threonine-protein kinase B-raf > Homo sapiens > 20148563 > J. Med. Chem.|2010|53|5|1964 > 87 > 2010 > 697114 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 20148563 > J. Med. Chem.|2010|53|5|1964 > 87 > 2010 $$$$