Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 57 61 0 0 0 0 0 0 0 0999 V2000 -1.1972 -0.8822 2.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5452 -1.2876 3.4108 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6893 -1.9023 3.3124 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2568 -2.1086 2.1396 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6756 -1.7404 1.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5762 -1.1122 1.0286 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2953 -1.9723 -0.1724 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5518 -2.4892 -0.1438 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6328 -1.6707 -0.3095 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9283 -2.1786 -0.2780 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1549 -3.5225 -0.0785 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7431 -3.8705 0.0628 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0590 -4.3940 0.0961 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2484 -5.7694 0.3024 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1676 -6.5813 0.4676 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8735 -6.0669 0.4349 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6527 -4.7379 0.2369 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2300 -0.6984 -0.2348 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4794 -0.0715 -0.2153 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0480 0.3020 -1.4195 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3979 0.0571 -2.5464 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2141 -0.5390 -2.5357 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6341 -0.9128 -1.4064 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4620 -4.0197 -0.0495 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4848 -3.2075 0.2832 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5680 -0.7766 -3.7364 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1931 -0.3705 -4.9976 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7541 -3.6525 0.1976 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2624 -2.0732 0.6607 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8078 -2.8546 0.6571 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5827 -1.9075 1.6475 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6249 -1.1219 2.0992 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8914 -1.2776 1.5665 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1187 -2.2195 0.5799 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0819 -3.0122 0.1279 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1642 -0.4039 2.3089 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9970 -1.1248 4.3781 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1980 -2.2185 4.2111 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4799 -0.6134 -0.4678 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7663 -1.5106 -0.4121 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2462 -6.1817 0.3297 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3160 -7.6393 0.6259 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0330 -6.7319 0.5682 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6439 -4.3529 0.2142 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9889 0.1164 0.7183 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0122 0.7881 -1.4403 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6323 -4.9491 -0.2688 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2988 -1.2120 -3.7429 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5410 -0.6379 -5.8290 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1507 -0.8791 -5.1087 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3527 0.7078 -4.9933 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9372 -4.5259 -0.1826 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5937 -1.7852 2.0637 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4504 -0.3849 2.8692 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7047 -0.6620 1.9214 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1089 -2.3385 0.1656 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2601 -3.7477 -0.6426 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 36 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 26 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 28 1 0 0 0 0 25 29 2 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 30 1 0 0 0 0 28 52 1 0 0 0 0 30 31 2 0 0 0 0 30 35 1 0 0 0 0 31 32 1 0 0 0 0 31 53 1 0 0 0 0 32 33 2 0 0 0 0 32 54 1 0 0 0 0 33 34 1 0 0 0 0 33 55 1 0 0 0 0 34 35 2 0 0 0 0 34 56 1 0 0 0 0 35 57 1 0 0 0 0 M END > 595995 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 7 > 2010 > 595995 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19062275 > Bioorg. Med. Chem. Lett.|2009|19|2|424 > 9 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 50 53 0 0 0 0 0 0 0 0999 V2000 -0.0178 1.4634 0.0101 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1205 2.2627 0.0309 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6980 3.6679 0.0325 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6443 3.7493 0.0131 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1813 2.3833 0.0036 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5223 1.7890 0.0490 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1859 1.2617 1.1089 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4636 0.9468 0.7422 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4699 1.8040 -1.0775 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6693 1.2643 -0.5829 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7657 1.1497 -1.4324 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6630 1.5645 -2.7420 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4752 2.0962 -3.2245 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3886 2.2225 -2.4047 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5126 -0.6933 -1.1050 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5347 -2.0749 -1.1061 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0502 -2.7819 -0.0086 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4588 -2.1005 1.0941 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4842 -0.7189 1.1036 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9312 -2.7957 2.1633 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.4388 -2.0332 3.2601 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0737 -4.1413 -0.0137 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2453 -4.7718 0.5077 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0299 -2.7452 -2.1809 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5098 -1.9572 -3.2721 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4531 4.6216 0.0487 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.4691 0.3563 1.6290 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1660 4.5671 0.0100 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7953 2.2153 0.8883 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7693 2.2175 -0.8991 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7671 1.1132 2.0933 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6939 0.7365 -1.0662 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5148 1.4747 -3.3998 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4116 2.4203 -4.2527 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4674 2.6374 -2.7864 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8883 -0.1457 -1.9567 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8787 -0.1912 1.9593 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7825 -2.7083 4.0438 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6496 -1.3921 3.6530 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2714 -1.4174 2.9200 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1339 -5.8543 0.4448 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1139 -4.4616 -0.0732 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3817 -4.4805 1.5491 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3210 -1.3156 -2.9279 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8760 -2.6141 -4.0612 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6986 -1.3410 -3.6597 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0293 1.1504 2.1228 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1517 -0.2605 1.0444 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9745 -0.2602 2.3795 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 6 1 0 0 0 0 3 4 1 0 0 0 0 3 27 2 0 0 0 0 4 5 1 0 0 0 0 4 29 1 0 0 0 0 5 30 1 0 0 0 0 5 31 1 0 0 0 0 6 9 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 32 1 0 0 0 0 8 10 1 0 0 0 0 8 28 1 0 0 0 0 9 14 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 33 1 0 0 0 0 12 13 1 0 0 0 0 12 34 1 0 0 0 0 13 14 2 0 0 0 0 13 35 1 0 0 0 0 14 36 1 0 0 0 0 15 16 2 0 0 0 0 15 20 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 17 18 2 0 0 0 0 17 25 1 0 0 0 0 18 19 1 0 0 0 0 18 23 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 20 38 1 0 0 0 0 21 22 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 24 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 28 50 1 0 0 0 0 M END > 549270 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 31 > 2008 > 549270 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 31 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 75 80 0 0 0 0 0 0 0 0999 V2000 -0.0728 1.2628 0.1002 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1307 1.9115 0.4100 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1500 3.2583 0.6975 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2509 1.9538 0.0709 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2583 3.3237 0.3590 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0466 3.9850 0.6790 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0822 5.2979 0.9563 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2187 5.9524 0.9306 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3741 5.3772 0.6375 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4515 4.0848 0.3480 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2902 1.2039 0.4272 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4831 1.9212 0.7505 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0667 -0.0679 -0.1799 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.3246 -0.6718 -0.4881 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6633 3.4981 0.0437 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8451 4.2335 0.1637 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8752 5.3729 0.9575 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0382 6.1043 1.0744 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.1885 5.7005 0.3944 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.1593 4.5551 -0.4045 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9919 3.8254 -0.5187 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.4352 6.4836 0.5197 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.5658 7.5533 1.2304 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.9500 6.0955 -0.2840 S 0 0 0 0 0 0 0 0 0 0 0 0 -10.7135 7.5053 0.4461 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7652 8.1601 1.2404 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.1599 9.3288 1.9287 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.4318 9.8005 1.8179 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.3663 9.1450 1.0285 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.0110 8.0040 0.3449 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6772 0.9651 0.7202 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9544 1.7331 1.0664 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1009 0.8151 1.0372 N 0 0 0 0 0 0 0 0 0 0 0 0 8.3686 1.5527 1.1297 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5317 0.5589 1.1763 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5020 -0.2827 -0.0281 N 0 0 0 0 0 0 0 0 0 0 0 0 8.2342 -1.0203 -0.1205 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0712 -0.0265 -0.1671 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6484 -1.2007 -0.0572 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9601 2.7101 -1.2961 O 0 0 0 0 0 0 0 0 0 0 0 0 -7.1704 2.3515 -1.9659 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0815 3.7503 0.9359 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1720 1.4456 -0.1732 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2114 7.0079 1.1592 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6368 2.7177 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3887 2.3531 1.7469 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1783 -1.7327 -0.6910 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0013 -0.5537 0.3582 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7536 -0.1896 -1.3664 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6943 2.5753 -0.2535 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9861 5.6864 1.4844 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0592 6.9897 1.6925 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.0477 4.2405 -0.9320 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.4467 9.8521 2.5483 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.7173 10.6954 2.3508 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.3722 9.5301 0.9502 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.7387 7.4941 -0.2690 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5235 0.1687 1.4484 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7717 0.5333 -0.2761 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1081 2.5296 0.3382 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8600 2.1650 2.0627 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4774 2.1993 0.2590 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3715 2.1587 2.0357 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4746 1.1043 1.2156 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4376 -0.0698 2.0617 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2313 -1.6263 -1.0265 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1254 -1.6669 0.7502 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1282 -0.5719 -0.2064 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1653 0.6022 -1.0525 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6197 -1.8459 0.8209 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6019 -1.8117 -0.9586 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5744 -0.6257 -0.0554 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.9540 2.1730 -1.2295 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.4727 3.1621 -2.6289 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0078 1.4458 -2.5501 H 0 0 0 0 0 0 0 0 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 42 1 0 0 0 0 4 5 2 0 0 0 0 4 43 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 44 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 45 1 0 0 0 0 12 46 1 0 0 0 0 13 14 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 14 49 1 0 0 0 0 15 16 1 0 0 0 0 15 50 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 51 1 0 0 0 0 18 19 2 0 0 0 0 18 52 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 53 1 0 0 0 0 21 40 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 54 1 0 0 0 0 28 29 1 0 0 0 0 28 55 1 0 0 0 0 29 30 2 0 0 0 0 29 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 58 1 0 0 0 0 31 59 1 0 0 0 0 32 33 1 0 0 0 0 32 60 1 0 0 0 0 32 61 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 62 1 0 0 0 0 34 63 1 0 0 0 0 35 36 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 38 68 1 0 0 0 0 38 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 39 72 1 0 0 0 0 40 41 1 0 0 0 0 41 73 1 0 0 0 0 41 74 1 0 0 0 0 41 75 1 0 0 0 0 M END > 691666 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 8 > 2009 > 691666 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 8 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 55 58 0 0 0 0 0 0 0 0999 V2000 5.0633 1.5656 -0.1328 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9629 0.2980 -0.4884 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6117 -0.6695 0.4285 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3601 -0.2979 1.7489 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8330 1.9618 1.1105 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4744 1.0450 2.0909 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0115 -1.2247 2.6776 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8330 -2.5078 2.2635 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5605 -2.9682 1.9623 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3787 -4.2699 1.5366 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4704 -5.1182 1.4100 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7458 -4.6579 1.7111 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9270 -3.3555 2.1369 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1671 -2.9066 2.4296 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2856 -6.4377 0.9794 N 0 0 0 0 0 0 0 0 0 0 0 0 4.2738 -7.0768 0.3224 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0674 -8.4469 -0.1602 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3373 -6.5174 0.1295 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7832 -9.0410 -0.1169 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6098 -10.2971 -0.5687 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6482 -11.0154 -1.0705 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8958 -10.4968 -1.1349 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1380 -9.1910 -0.6789 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8361 -8.4164 0.3293 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3342 -10.8749 -0.5204 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6470 -11.1422 -1.6970 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6077 -11.7169 -1.6474 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1808 -12.0263 -0.4252 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4970 -11.7605 0.7494 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7581 -11.1862 0.7041 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4087 -12.5877 -0.3787 F 0 0 0 0 0 0 0 0 0 0 0 0 4.9520 3.3086 1.4374 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1731 1.5683 3.7184 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.3801 -8.6609 -0.7376 O 0 0 0 0 0 0 0 0 0 0 0 0 7.2996 -9.0475 0.2856 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6001 -8.2571 0.1279 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1584 0.0153 -1.5123 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5319 -1.7036 0.1276 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7107 -2.3090 2.0609 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3870 -4.6277 1.3025 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5953 -5.3175 1.6131 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4464 -6.8919 1.1538 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4741 -12.0208 -1.4246 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7057 -11.0870 -1.5375 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0934 -10.9004 -2.6503 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1425 -11.9250 -2.5623 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9458 -12.0021 1.7016 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2911 -10.9794 1.6203 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7848 3.6037 2.3462 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2021 3.9527 0.7566 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8642 -8.8394 1.2630 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5099 -10.1137 0.2011 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3015 -8.5521 0.9084 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0356 -8.4652 -0.8494 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3898 -7.1909 0.2124 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 6 1 0 0 0 0 4 7 1 0 0 0 0 5 6 2 0 0 0 0 5 32 1 0 0 0 0 6 33 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 13 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 12 1 0 0 0 0 11 15 1 0 0 0 0 12 13 2 0 0 0 0 12 41 1 0 0 0 0 13 14 1 0 0 0 0 15 16 1 0 0 0 0 15 42 1 0 0 0 0 16 18 2 0 0 0 0 16 17 1 0 0 0 0 17 19 1 0 0 0 0 17 23 2 0 0 0 0 19 20 1 0 0 0 0 19 24 2 0 0 0 0 20 21 1 0 0 0 0 20 25 1 0 0 0 0 21 22 2 0 0 0 0 21 43 1 0 0 0 0 22 23 1 0 0 0 0 22 44 1 0 0 0 0 23 34 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 26 45 1 0 0 0 0 27 28 2 0 0 0 0 27 46 1 0 0 0 0 28 29 1 0 0 0 0 28 31 1 0 0 0 0 29 30 2 0 0 0 0 29 47 1 0 0 0 0 30 48 1 0 0 0 0 32 49 1 0 0 0 0 32 50 1 0 0 0 0 34 35 1 0 0 0 0 35 36 1 0 0 0 0 35 51 1 0 0 0 0 35 52 1 0 0 0 0 36 53 1 0 0 0 0 36 54 1 0 0 0 0 36 55 1 0 0 0 0 M END > 555596 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19260711 > J. Med. Chem.|2009|52|5|1251 > "10, BMS-777607" > 2009 > 555596 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19260711 > J. Med. Chem.|2009|52|5|1251 > "10, BMS-777607" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 48 52 0 0 0 0 0 0 0 0999 V2000 -0.0182 1.4010 0.0580 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0003 -0.0007 0.0637 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1925 -0.6891 0.0466 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1468 2.1139 0.0350 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3727 1.4383 0.0168 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3987 0.0214 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5874 -0.6017 0.0046 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7011 0.0910 -0.0183 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7256 1.4143 -0.0244 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6079 2.1286 -0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1722 -0.6875 0.0869 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.0881 -2.1141 0.0916 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2086 2.0582 0.0699 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1612 3.4864 0.0632 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6484 3.5087 -0.0148 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8724 4.1710 0.0815 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0671 5.3714 -0.5938 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2745 6.0277 -0.5007 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3038 5.4867 0.2727 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1054 4.2813 0.9496 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8938 3.6326 0.8571 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6004 6.1879 0.3743 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6116 5.7725 1.0608 N 0 0 0 0 0 0 0 0 0 0 0 0 8.9882 7.7032 -0.4287 S 0 0 0 0 0 0 0 0 0 0 0 0 10.6067 7.6722 0.2665 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7289 6.5198 1.0513 C 0 0 0 0 0 0 0 0 0 0 0 0 11.9552 6.2863 1.7123 C 0 0 0 0 0 0 0 0 0 0 0 0 12.9875 7.1642 1.5852 C 0 0 0 0 0 0 0 0 0 0 0 0 12.8580 8.3049 0.8054 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6756 8.5586 0.1476 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1974 -1.7691 0.0519 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1221 3.1936 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6401 -0.4423 -0.0326 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5385 -2.4427 0.9736 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0924 -2.5372 0.1107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5691 -2.4504 -0.8060 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6247 3.8363 0.9452 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6466 3.8287 -0.8346 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1762 3.8837 0.0741 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8259 4.0177 -0.0867 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2708 5.7890 -1.1921 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4252 6.9595 -1.0255 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8996 3.8605 1.5484 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7396 2.7006 1.3806 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0745 5.4042 2.3239 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9184 6.9710 2.0976 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6852 8.9933 0.7141 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5754 9.4465 -0.4591 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 31 1 0 0 0 0 4 5 2 0 0 0 0 4 32 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 33 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 34 1 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 13 14 1 0 0 0 0 14 37 1 0 0 0 0 14 38 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 16 17 2 0 0 0 0 16 21 1 0 0 0 0 17 18 1 0 0 0 0 17 41 1 0 0 0 0 18 19 2 0 0 0 0 18 42 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 43 1 0 0 0 0 21 44 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 28 46 1 0 0 0 0 29 30 2 0 0 0 0 29 47 1 0 0 0 0 30 48 1 0 0 0 0 M END > 557700 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "25, Table 4" > 2009 > 557700 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "25, Table 4" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 42 44 0 0 0 0 0 0 0 0999 V2000 0.0811 1.3454 0.6905 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2103 2.0707 0.2625 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4025 1.3955 0.0132 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1252 0.0498 0.8599 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2424 -0.6528 0.6361 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4231 0.0035 0.2030 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5895 -0.7441 -0.0281 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5738 -2.0964 0.1671 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4100 -2.7426 0.5934 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2650 -2.0449 0.8257 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7016 -2.8210 -0.0562 O 0 0 0 0 0 0 0 0 0 0 0 0 4.5913 -4.2418 0.0487 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6665 -4.8919 -0.7834 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7560 -4.6595 1.5114 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3552 -5.9632 -1.6013 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3418 -6.5606 -2.3656 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6392 -6.0878 -2.3127 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9525 -5.0160 -1.4944 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9634 -4.4138 -0.7337 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3547 -3.0698 0.2930 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.2208 -4.5537 -1.4421 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7259 -6.5587 -1.6683 Cl 0 0 0 0 0 0 0 0 0 0 0 0 1.1307 3.5284 0.0800 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0271 4.1763 0.3231 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1062 5.6266 0.1416 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2631 6.2740 0.3845 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8726 6.2478 -0.2288 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.8409 1.8722 0.8875 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2840 1.9254 -0.3162 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4930 -0.2532 -0.3583 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4196 -3.8125 0.7407 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3749 -2.5604 1.1551 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6122 -4.5578 -0.3114 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7350 -4.3435 1.8715 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9783 -4.1893 2.1133 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6718 -5.7433 1.5914 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0979 -7.3972 -3.0036 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4088 -6.5546 -2.9096 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9993 4.0797 -0.2487 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8957 3.6250 0.6518 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0432 5.7789 0.6797 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3155 7.2351 0.2642 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 2 0 0 0 0 1 2 1 0 0 0 0 1 28 1 0 0 0 0 2 3 2 0 0 0 0 2 23 1 0 0 0 0 3 6 1 0 0 0 0 3 29 1 0 0 0 0 4 5 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 30 1 0 0 0 0 8 9 2 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 9 31 1 0 0 0 0 10 32 1 0 0 0 0 11 12 1 0 0 0 0 12 13 1 0 0 0 0 12 14 1 0 0 0 0 12 33 1 0 0 0 0 13 15 2 0 0 0 0 13 19 1 0 0 0 0 14 34 1 0 0 0 0 14 35 1 0 0 0 0 14 36 1 0 0 0 0 15 16 1 0 0 0 0 15 22 1 0 0 0 0 16 17 2 0 0 0 0 16 37 1 0 0 0 0 17 18 1 0 0 0 0 17 38 1 0 0 0 0 18 19 2 0 0 0 0 18 21 1 0 0 0 0 19 20 1 0 0 0 0 23 24 2 0 0 0 0 23 39 1 0 0 0 0 24 25 1 0 0 0 0 24 40 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 41 1 0 0 0 0 26 42 1 0 0 0 0 M END > 702419 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20093027 > Bioorg. Med. Chem. Lett.|2010|20|4|1405 > (R)-3 > 2010 > 702419 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20093027 > Bioorg. Med. Chem. Lett.|2010|20|4|1405 > (R)-3 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 55 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8410 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3465 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6789 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -0.9593 0.0059 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1704 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0934 -1.5675 -0.7688 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6095 -3.2089 0.6661 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0263 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0372 -3.2644 0.3603 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2898 -2.2149 -0.5433 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5820 -2.0173 -1.0193 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6024 -2.8446 -0.6068 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3563 -3.8842 0.2873 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0823 -4.0981 0.7719 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3761 -4.6916 0.6840 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6701 -4.4151 0.1443 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6804 -5.4199 0.7016 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3419 -6.7686 0.2280 N 0 0 0 0 0 0 0 0 0 0 0 0 11.4154 -7.7225 0.5429 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9966 -9.1226 0.0867 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6921 -9.0921 -1.3103 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6503 -8.1740 -1.6525 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0554 -6.7642 -1.2139 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0009 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4432 -3.0501 -0.0017 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0252 -0.6586 0.0182 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9744 -0.8026 -1.3533 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0679 -3.8683 1.3281 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7848 -1.2148 -1.7131 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6033 -2.6862 -0.9803 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8931 -4.9046 1.4649 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6361 -4.4986 -0.9420 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9713 -3.4050 0.4219 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6815 -5.1557 0.3606 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6504 -5.3991 1.7910 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3276 -7.4282 0.0239 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5934 -7.7281 1.6183 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8123 -9.8230 0.2661 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1152 -9.4388 0.6445 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4922 -8.1883 -2.7309 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7297 -8.4626 -1.1452 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2406 -6.0704 -1.4210 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9458 -6.4546 -1.7610 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 29 1 0 0 0 0 1 30 1 0 0 0 0 2 3 1 0 0 0 0 2 31 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 6 10 1 0 0 0 0 7 8 1 0 0 0 0 7 32 1 0 0 0 0 8 9 2 0 0 0 0 8 33 1 0 0 0 0 9 34 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 35 1 0 0 0 0 12 14 1 0 0 0 0 12 36 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 37 1 0 0 0 0 17 18 1 0 0 0 0 17 38 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 39 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 22 42 1 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 26 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 M END > 592663 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12f > 2008 > 592663 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12f > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 80 85 0 0 0 0 0 0 0 0999 V2000 -0.0034 1.4220 0.0677 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0280 0.0270 -0.0702 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1258 -0.6896 -0.2072 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1914 2.0943 0.0738 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3928 1.3821 -0.0591 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3637 -0.0257 -0.2104 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5076 -0.7057 -0.3536 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.6720 -0.1005 -0.3583 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7823 1.2768 -0.2152 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6410 2.0445 -0.0632 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7182 3.3907 0.0789 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.9433 3.9726 -0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7516 4.0641 1.1173 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.9964 4.6553 1.0291 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.4413 5.1602 -0.1924 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.6270 5.0662 -1.3209 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.3825 4.4794 -1.2254 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.3192 3.5740 2.2997 F 0 0 0 0 0 0 0 0 0 0 0 0 -8.7765 5.7948 -0.2913 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.8050 5.2110 -1.0791 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.0047 5.8284 -1.1295 N 0 0 0 0 0 0 0 0 0 0 0 0 -11.2073 6.9708 -0.4440 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.2686 7.5157 0.2831 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.0569 6.9688 0.3858 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.6086 4.1775 -1.6952 O 0 0 0 0 0 0 0 0 0 0 0 0 -12.0885 5.2553 -1.9316 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.5557 7.6395 -0.5188 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.5435 8.8900 0.3221 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.1713 10.0970 -0.2396 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.1601 11.2441 0.5317 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.5216 11.1843 1.8646 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.8947 9.9774 2.4261 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.9101 8.8311 1.6536 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1608 2.1116 0.2022 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0623 3.5306 0.3387 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2229 -0.6201 -0.0677 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1912 -2.0415 -0.2123 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6197 -2.5887 -0.1866 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5858 -4.1105 -0.3414 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9574 -4.6359 -0.3167 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9579 -6.1031 -0.2241 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4018 -6.6109 -0.2615 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1438 -6.0012 0.7982 O 0 0 0 0 0 0 0 0 0 0 0 0 6.1647 -4.5725 0.7386 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7286 -4.0441 0.7861 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0869 -1.7636 -0.3133 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2069 3.1679 0.1895 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5694 -0.6896 -0.4770 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7547 1.7467 -0.2234 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.6247 4.7262 1.9047 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.9691 5.4564 -2.2680 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7522 4.4067 -2.0994 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.2985 7.4393 0.9940 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.0429 5.6569 -2.9438 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.9811 4.1711 -1.9657 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.0478 5.5114 -1.4819 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.7752 7.9000 -1.5542 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.3203 6.9582 -0.1457 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.8889 10.1438 -1.2810 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.8686 12.1870 0.0930 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.5122 12.0803 2.4674 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.1768 9.9306 3.4675 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.2016 7.8883 2.0923 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0608 3.9563 0.4375 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5752 3.9475 -0.5428 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4757 3.7705 1.2255 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6203 -2.4774 0.6076 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7201 -2.2998 -1.1607 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1906 -2.1528 -1.0065 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0908 -2.3304 0.7618 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0149 -4.5464 0.4785 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1147 -4.3688 -1.2898 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4886 -6.4090 0.7109 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4033 -6.5210 -1.0643 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4102 -7.6936 -0.1358 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8541 -6.3515 -1.2187 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7248 -4.1809 1.5877 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6392 -4.2538 -0.1895 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7364 -2.9589 0.6835 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2716 -4.3170 1.7373 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 34 1 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 36 1 0 0 0 0 3 6 2 0 0 0 0 3 46 1 0 0 0 0 4 5 2 0 0 0 0 4 47 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 48 1 0 0 0 0 9 10 2 0 0 0 0 9 49 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 17 1 0 0 0 0 13 14 1 0 0 0 0 13 18 1 0 0 0 0 14 15 2 0 0 0 0 14 50 1 0 0 0 0 15 16 1 0 0 0 0 15 19 1 0 0 0 0 16 17 2 0 0 0 0 16 51 1 0 0 0 0 17 52 1 0 0 0 0 19 24 2 0 0 0 0 19 20 1 0 0 0 0 20 25 2 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 26 1 0 0 0 0 22 23 2 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 24 53 1 0 0 0 0 26 54 1 0 0 0 0 26 55 1 0 0 0 0 26 56 1 0 0 0 0 27 28 1 0 0 0 0 27 57 1 0 0 0 0 27 58 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 29 59 1 0 0 0 0 30 31 2 0 0 0 0 30 60 1 0 0 0 0 31 32 1 0 0 0 0 31 61 1 0 0 0 0 32 33 2 0 0 0 0 32 62 1 0 0 0 0 33 63 1 0 0 0 0 34 35 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 35 66 1 0 0 0 0 36 37 1 0 0 0 0 37 38 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 38 39 1 0 0 0 0 38 69 1 0 0 0 0 38 70 1 0 0 0 0 39 40 1 0 0 0 0 39 71 1 0 0 0 0 39 72 1 0 0 0 0 40 41 1 0 0 0 0 40 45 1 0 0 0 0 41 42 1 0 0 0 0 41 73 1 0 0 0 0 41 74 1 0 0 0 0 42 43 1 0 0 0 0 42 75 1 0 0 0 0 42 76 1 0 0 0 0 43 44 1 0 0 0 0 44 45 1 0 0 0 0 44 77 1 0 0 0 0 44 78 1 0 0 0 0 45 79 1 0 0 0 0 45 80 1 0 0 0 0 M END > 570982 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18763753 > J. Med. Chem.|2008|51|18|5766 > 22 > 2008 > 570982 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18763753 > J. Med. Chem.|2008|51|18|5766 > 22 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 56 61 0 0 0 0 0 0 0 0999 V2000 -1.0574 -0.6762 2.4214 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3261 -0.9522 3.5646 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9047 -1.5717 3.4507 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3941 -1.9043 2.2718 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7354 -1.6626 1.1510 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5179 -1.0380 1.1850 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2767 -2.0212 -0.0386 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5381 -2.5271 -0.0390 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5895 -1.7446 -0.4240 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8897 -2.2410 -0.4268 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1512 -3.5375 -0.0406 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7653 -3.8589 0.3634 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0862 -4.3710 0.3631 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3113 -5.6969 0.7641 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2599 -6.4729 1.1479 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9609 -5.9698 1.1483 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7058 -4.6883 0.7650 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2581 -0.7654 -0.0690 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5089 -0.1419 -0.0337 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1599 0.0971 -1.2304 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5844 -0.2684 -2.3651 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.3974 -0.8580 -2.3694 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7400 -1.1055 -1.2477 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4613 -4.0238 -0.0489 N 0 0 0 0 0 0 0 0 0 0 0 0 7.5127 -3.1692 -0.3101 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8185 -3.5484 -0.4402 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4067 -1.8742 -0.4758 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6340 -1.3430 -0.7158 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5547 -2.4036 -0.6967 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9012 -2.1556 -0.9166 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3328 -0.8662 -1.1499 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4284 0.1854 -1.1662 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0868 -0.0435 -0.9581 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8308 -1.2243 -3.5779 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.5424 -0.9591 -4.8308 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0232 -0.1970 2.4847 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7138 -0.6854 4.5367 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4752 -1.7866 4.3421 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4090 -0.7251 -0.7312 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7038 -1.6022 -0.7360 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3133 -6.1001 0.7679 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4357 -7.4930 1.4560 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1442 -6.6056 1.4567 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6937 -4.3116 0.7703 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9565 0.1460 0.9061 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1276 0.5766 -1.2389 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6315 -4.9620 0.1289 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1655 -4.4512 -0.3663 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6105 -2.9700 -0.9048 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3818 -0.6743 -1.3206 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7785 1.1905 -1.3495 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3881 0.7799 -0.9721 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0374 -1.6565 -3.5953 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9449 -1.3147 -5.6702 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5008 -1.4782 -4.8212 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7108 0.1129 -4.9331 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 36 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 49 1 0 0 0 0 31 32 1 0 0 0 0 31 50 1 0 0 0 0 32 33 2 0 0 0 0 32 51 1 0 0 0 0 33 52 1 0 0 0 0 34 35 1 0 0 0 0 34 53 1 0 0 0 0 35 54 1 0 0 0 0 35 55 1 0 0 0 0 35 56 1 0 0 0 0 M END > 595994 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19062275 > Bioorg. Med. Chem. Lett.|2009|19|2|424 > 8 > 2009 > 595994 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19062275 > Bioorg. Med. Chem. Lett.|2009|19|2|424 > 8 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 59 64 0 0 0 0 0 0 0 0999 V2000 -0.1294 1.2660 0.2079 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0661 1.9607 0.2850 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2598 1.2635 0.2590 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2792 -0.0519 0.1619 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1657 -0.7610 0.0855 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0827 -0.1262 0.1057 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2328 -2.1110 -0.0136 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4627 -2.6891 -0.0305 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0572 -3.0681 1.1395 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3137 -3.6665 1.1446 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9925 -3.8930 -0.0329 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1254 -2.9045 -1.2559 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4046 -3.5132 -1.2585 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0634 -3.7272 -2.4790 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4662 -3.3484 -3.6429 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2084 -2.7498 -3.6409 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5406 -2.5265 -2.4754 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3320 -0.9177 0.0198 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5774 -0.2828 0.0401 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7161 -1.0630 -0.0484 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5946 -2.3773 -0.1489 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4010 -2.9531 -0.1659 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2860 -2.2447 -0.0836 N 0 0 0 0 0 0 0 0 0 0 0 0 6.2540 -4.4939 -0.0137 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9027 -4.6982 1.1868 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0769 -5.3792 1.3384 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4872 -4.2630 2.3504 N 0 0 0 0 0 0 0 0 0 0 0 0 7.3626 -4.6414 3.3181 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3914 -5.3601 2.6872 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4384 -5.8732 3.4377 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4643 -5.6789 4.8033 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4491 -4.9730 5.4319 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4061 -4.4494 4.7014 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3182 -4.3306 -0.2723 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.5405 -5.1329 -0.3645 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3416 -2.8341 2.4450 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0748 1.7877 0.2307 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0661 3.0377 0.3645 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1922 1.8051 0.3188 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7624 -3.9567 2.0831 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0393 -4.1897 -2.4952 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9752 -3.5142 -4.5809 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7564 -2.4581 -4.5774 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5661 -2.0612 -2.4888 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6487 0.7916 0.1233 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6940 -0.6047 -0.0352 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6736 -4.7674 -0.8444 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5941 -5.7985 0.6330 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2317 -6.4240 2.9543 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2801 -6.0793 5.3868 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4803 -4.8278 6.5017 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6190 -3.9009 5.1973 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4509 -4.7648 -0.2858 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1478 -4.9736 0.5265 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1056 -4.8340 -1.2474 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2777 -6.1879 -0.4413 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7284 -3.7030 2.6840 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0735 -2.6769 3.2374 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7055 -1.9533 2.3579 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 37 1 0 0 0 0 2 3 1 0 0 0 0 2 38 1 0 0 0 0 3 4 2 0 0 0 0 3 39 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 36 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 49 1 0 0 0 0 31 32 1 0 0 0 0 31 50 1 0 0 0 0 32 33 2 0 0 0 0 32 51 1 0 0 0 0 33 52 1 0 0 0 0 34 35 1 0 0 0 0 34 53 1 0 0 0 0 35 54 1 0 0 0 0 35 55 1 0 0 0 0 35 56 1 0 0 0 0 36 57 1 0 0 0 0 36 58 1 0 0 0 0 36 59 1 0 0 0 0 M END > 596140 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19062275 > Bioorg. Med. Chem. Lett.|2009|19|2|424 > 15 > 2009 > 596140 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 3 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 56 59 0 0 0 999 V2000 0.7106 1.0367 -0.2945 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8463 -0.3111 -0.1490 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0619 -0.8761 0.2169 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1730 -0.0781 0.4436 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8108 1.8848 -0.0747 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0583 1.3278 0.2984 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1562 2.1706 0.5174 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0185 3.5172 0.3706 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7917 4.0767 0.0024 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6935 3.2770 -0.2194 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4598 -0.6848 0.8321 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5387 -2.0113 1.0571 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4496 0.0117 0.9493 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6817 5.4239 -0.1367 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2185 5.9952 -1.2419 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3199 7.1413 -3.5093 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3051 5.8353 -3.3733 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7628 5.2212 -2.2528 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8029 7.9509 -2.5786 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2350 7.4009 -1.4013 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7029 8.2461 -0.4220 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7365 9.6192 -0.6136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3028 10.1599 -1.7877 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8241 9.3453 -2.7493 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3285 11.5052 -1.9620 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9149 11.9916 -3.1710 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8170 -2.6140 1.4430 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6328 -4.1206 1.6361 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2930 -4.7230 0.3857 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0979 -6.1369 0.4557 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1777 10.5181 0.4137 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2059 11.7224 0.2482 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6358 10.0046 1.5358 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.2425 1.4543 -0.5835 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0061 -0.9516 -0.3206 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1421 -1.9476 0.3260 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1103 1.7527 0.8027 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8683 4.1615 0.5412 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7490 3.7167 -0.5040 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7491 -2.5669 0.9636 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7346 5.2219 -4.1515 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7656 4.1444 -2.1697 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2688 7.8325 0.4763 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2540 9.7727 -3.6430 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8710 13.0806 -3.1836 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9547 11.6692 -3.2258 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3663 11.5959 -4.0257 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5540 -2.4355 0.6600 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1623 -2.1677 2.3755 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5604 -4.5552 2.0086 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8333 -4.2997 2.3549 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8432 -6.5180 -0.5333 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0144 -6.6134 0.8037 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2872 -6.3579 1.1500 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6133 9.0438 1.6678 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2684 10.5957 2.2114 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 34 1 0 0 0 0 2 3 1 0 0 0 0 2 35 1 0 0 0 0 3 4 2 0 0 0 0 3 36 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 37 1 0 0 0 0 8 9 2 0 0 0 0 8 38 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 39 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 27 1 0 0 0 0 12 40 1 0 0 0 0 14 15 1 0 0 0 0 15 18 1 0 0 0 0 15 20 2 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 41 1 0 0 0 0 18 42 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 43 1 0 0 0 0 22 23 1 0 0 0 0 22 31 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 29 30 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 32 2 0 0 0 0 31 33 1 0 0 0 0 33 55 1 0 0 0 0 33 56 1 0 0 0 0 M END > 541050 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 30 > 2008 > 541050 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 30 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 42 45 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8410 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3465 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6789 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -0.9593 0.0059 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1704 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0944 -1.5642 -0.7646 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6084 -3.2123 0.6619 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0263 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0354 -3.2703 0.3529 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2905 -2.2127 -0.5405 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5833 -2.0129 -1.0137 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6030 -2.8424 -0.6040 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3556 -3.8865 0.2844 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0795 -4.1073 0.7604 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3747 -4.6964 0.6781 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6693 -4.4177 0.1412 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6786 -5.4257 0.6944 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0648 -5.1273 0.1195 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0075 -6.0688 0.6362 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0009 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4432 -3.0501 -0.0017 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0252 -0.6586 0.0182 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9763 -0.7966 -1.3457 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0653 -3.8764 1.3180 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7872 -1.2069 -1.7032 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6045 -2.6823 -0.9754 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8893 -4.9170 1.4494 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6364 -4.4956 -0.9455 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9706 -3.4091 0.4242 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7115 -5.3479 1.7811 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3773 -6.4343 0.4114 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0319 -5.2052 -0.9672 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3661 -4.1188 0.4026 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9098 -5.9395 0.3135 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 25 1 0 0 0 0 1 26 1 0 0 0 0 2 3 1 0 0 0 0 2 27 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 28 1 0 0 0 0 8 9 2 0 0 0 0 8 29 1 0 0 0 0 9 30 1 0 0 0 0 10 12 2 0 0 0 0 10 11 1 0 0 0 0 11 15 1 0 0 0 0 11 31 1 0 0 0 0 12 14 1 0 0 0 0 12 32 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 33 1 0 0 0 0 17 18 1 0 0 0 0 17 34 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 35 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 22 23 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 42 1 0 0 0 0 M END > 592660 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12c > 2008 > 592660 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12c > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 78 83 0 0 0 0 0 0 0 0999 V2000 -0.8777 0.3165 -1.0580 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4006 0.8784 -0.9310 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5579 2.2001 -0.6282 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9947 1.0821 -0.8867 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8622 2.4434 -0.5747 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5724 3.0127 -0.4403 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4433 4.3101 -0.1382 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.4891 5.0826 0.0401 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7859 4.5980 -0.0746 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9956 3.2657 -0.3845 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0060 -1.0030 -1.3604 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.3348 -1.5159 -1.4761 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4975 0.0967 -1.1112 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7728 0.7255 -0.9684 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2500 2.7648 -0.5025 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.2958 3.6105 -0.3070 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6641 4.5159 -1.2995 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.7340 5.3578 -1.0600 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.4049 5.2729 0.1604 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.0240 4.3964 1.0823 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.0117 3.5775 0.8811 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.5518 6.1687 0.4302 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.2496 6.1016 1.6625 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.2893 6.9395 1.8618 N 0 0 0 0 0 0 0 0 0 0 0 0 -10.6472 7.8228 0.8910 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.0002 7.8878 -0.2564 N 0 0 0 0 0 0 0 0 0 0 0 0 -8.9647 7.0972 -0.5155 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.7049 8.6645 1.1103 N 0 0 0 0 0 0 0 0 0 0 0 0 -12.0237 9.6482 0.1671 C 0 0 0 0 0 0 0 0 0 0 0 0 -13.3458 10.0300 -0.0197 C 0 0 0 0 0 0 0 0 0 0 0 0 -13.6581 11.0009 -0.9510 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.6541 11.5935 -1.6982 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.3352 11.2140 -1.5139 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.0178 10.2479 -0.5793 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8788 -0.3048 -1.2056 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2442 0.3684 -1.0527 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3061 -0.6208 -1.2805 N 0 0 0 0 0 0 0 0 0 0 0 0 7.6206 0.0303 -1.3771 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7019 -1.0390 -1.5541 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4016 -1.8268 -2.7094 O 0 0 0 0 0 0 0 0 0 0 0 0 7.1287 -2.4758 -2.6487 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0315 -1.4211 -2.4828 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.9619 12.5430 -2.6087 F 0 0 0 0 0 0 0 0 0 0 0 0 -11.0326 6.8972 3.1236 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.9182 5.3043 2.5233 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5485 2.6198 -0.5330 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9755 0.6422 -0.9911 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3374 6.1240 0.2830 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6270 5.2582 0.0774 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8604 -1.3795 -0.5310 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8629 -0.9817 -2.2659 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2945 -2.5776 -1.7196 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8643 1.5311 -1.6969 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 1.1334 0.0381 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1257 4.5593 -2.2348 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0463 6.0721 -1.8074 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7302 2.8776 1.6540 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.4513 7.1703 -1.4628 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.2332 8.5789 1.9193 H 0 0 0 0 0 0 0 0 0 0 0 0 -14.1291 9.5679 0.5626 H 0 0 0 0 0 0 0 0 0 0 0 0 -14.6862 11.2979 -1.0968 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.5538 11.6772 -2.0979 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.9891 9.9522 -0.4358 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7872 -1.1104 -0.4771 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7855 -0.7127 -2.2121 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3357 1.1740 -1.7812 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3374 0.7763 -0.0462 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6311 0.7038 -2.2340 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8143 0.5964 -0.4660 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6716 -0.5583 -1.6834 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7274 -1.6802 -0.6730 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9606 -3.0342 -3.5696 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1085 -3.1588 -1.7994 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0651 -1.9144 -2.3787 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0166 -0.7707 -3.3573 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.6041 6.1331 3.7722 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.9697 7.8680 3.6151 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.0770 6.6589 2.9222 H 0 0 0 0 0 0 0 0 0 0 0 0 1 11 1 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 13 1 0 0 0 0 3 6 2 0 0 0 0 3 46 1 0 0 0 0 4 5 2 0 0 0 0 4 47 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 48 1 0 0 0 0 9 10 2 0 0 0 0 9 49 1 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 50 1 0 0 0 0 12 51 1 0 0 0 0 12 52 1 0 0 0 0 13 14 1 0 0 0 0 14 35 1 0 0 0 0 14 53 1 0 0 0 0 14 54 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 21 1 0 0 0 0 17 18 1 0 0 0 0 17 55 1 0 0 0 0 18 19 2 0 0 0 0 18 56 1 0 0 0 0 19 22 1 0 0 0 0 19 20 1 0 0 0 0 20 21 2 0 0 0 0 21 57 1 0 0 0 0 22 23 1 0 0 0 0 22 27 2 0 0 0 0 23 24 1 0 0 0 0 23 45 2 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 25 26 2 0 0 0 0 25 28 1 0 0 0 0 26 27 1 0 0 0 0 27 58 1 0 0 0 0 28 29 1 0 0 0 0 28 59 1 0 0 0 0 29 30 2 0 0 0 0 29 34 1 0 0 0 0 30 31 1 0 0 0 0 30 60 1 0 0 0 0 31 32 2 0 0 0 0 31 61 1 0 0 0 0 32 33 1 0 0 0 0 32 43 1 0 0 0 0 33 34 2 0 0 0 0 33 62 1 0 0 0 0 34 63 1 0 0 0 0 35 36 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 36 37 1 0 0 0 0 36 66 1 0 0 0 0 36 67 1 0 0 0 0 37 38 1 0 0 0 0 37 42 1 0 0 0 0 38 39 1 0 0 0 0 38 68 1 0 0 0 0 38 69 1 0 0 0 0 39 40 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 40 41 1 0 0 0 0 41 42 1 0 0 0 0 41 72 1 0 0 0 0 41 73 1 0 0 0 0 42 74 1 0 0 0 0 42 75 1 0 0 0 0 44 76 1 0 0 0 0 44 77 1 0 0 0 0 44 78 1 0 0 0 0 M END > 571225 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18763753 > J. Med. Chem.|2008|51|18|5766 > 62 > 2008 > 571225 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18763753 > J. Med. Chem.|2008|51|18|5766 > 62 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 41 45 0 0 0 0 0 0 0 0999 V2000 -0.0040 1.4075 -0.4062 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1310 2.0865 0.0250 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2417 1.3775 0.4710 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2205 0.0004 0.4869 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0823 -0.6841 0.0550 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0312 0.0305 -0.3923 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0565 -2.1613 0.0703 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0566 -2.8853 -0.3069 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3862 -3.1835 0.5979 S 0 0 0 0 0 0 0 0 0 0 0 0 1.4314 -4.6240 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1839 -4.2216 -0.2344 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7531 -5.2198 -0.5820 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4448 -6.5377 -0.4388 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7935 -6.9284 0.0510 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7293 -5.9785 0.3936 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1556 3.4806 0.0097 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6262 4.1718 -1.0702 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2077 3.5044 -2.2107 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3184 4.2242 -3.2748 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4340 5.5313 -3.2375 N 0 0 0 0 0 0 0 0 0 0 0 0 0.4908 5.5805 -1.0401 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0505 6.2405 -2.1694 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1803 7.6391 -2.1455 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2187 8.3366 -1.0447 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7560 7.6836 0.0629 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8861 6.3272 0.0780 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0558 10.0648 -1.0223 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -0.8663 1.9607 -0.7480 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1216 1.9073 0.8048 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0833 -0.5496 0.8326 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9128 -0.4962 -0.7268 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7222 -4.9349 -0.9642 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1726 -7.2884 -0.7093 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0245 -7.9778 0.1601 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6949 -6.2832 0.7693 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5430 3.9670 0.7542 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2908 2.4293 -2.2714 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6413 3.6939 -4.1584 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5945 8.1597 -2.9963 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0652 8.2588 0.9232 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3038 5.8315 0.9418 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 28 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 29 1 0 0 0 0 4 5 1 0 0 0 0 4 30 1 0 0 0 0 5 7 1 0 0 0 0 5 6 2 0 0 0 0 6 31 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 32 1 0 0 0 0 13 14 1 0 0 0 0 13 33 1 0 0 0 0 14 15 2 0 0 0 0 14 34 1 0 0 0 0 15 35 1 0 0 0 0 16 17 1 0 0 0 0 16 36 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 18 37 1 0 0 0 0 19 20 2 0 0 0 0 19 38 1 0 0 0 0 20 22 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 23 39 1 0 0 0 0 24 25 2 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 40 1 0 0 0 0 26 41 1 0 0 0 0 M END > 557627 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "20, Table 4" > 2009 > 557627 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "20, Table 4" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 72 78 0 0 0 0 0 0 0 0999 V2000 0.0901 1.6503 1.5691 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1247 0.3611 1.0726 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3131 -0.3409 1.0448 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4837 0.2505 1.5192 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4493 1.5506 2.0200 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2516 2.2481 2.0437 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7601 -0.5014 1.4913 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9100 -1.8624 1.6922 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9760 0.0137 1.2611 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8735 -0.9462 1.3069 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2762 -2.1390 1.5713 N 0 0 0 0 0 0 0 0 0 0 0 0 6.1190 -3.2224 1.6433 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4139 -3.0338 1.4557 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6029 -1.2974 1.1540 S 0 0 0 0 0 0 0 0 0 0 0 0 2.8408 -2.8301 1.9780 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0013 -4.1867 1.6558 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9714 -5.0577 1.9489 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7021 -2.4339 2.5537 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7425 -3.3063 2.8155 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8700 -4.5925 2.5210 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.4263 -2.8640 3.4136 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.4030 -3.7846 3.8049 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0296 -5.0411 4.2655 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9941 -5.9497 4.6574 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7464 -3.4422 3.7391 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7124 -4.3568 4.1338 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3320 -5.6124 4.5928 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0654 -4.0161 4.0696 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.9107 -5.1262 4.5329 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3780 -4.6902 4.5026 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.7171 -4.2672 3.1792 O 0 0 0 0 0 0 0 0 0 0 0 0 -6.9138 -3.1869 2.6964 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.4418 -3.6077 2.7085 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2121 3.5540 2.5452 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2526 4.3860 2.3412 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1844 4.0334 1.6495 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2582 5.7543 2.9727 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5236 6.4783 2.5912 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5565 7.2584 1.4505 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7173 7.9225 1.1005 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8450 7.8070 1.8916 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8118 7.0277 3.0328 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6498 6.3670 3.3851 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8415 2.1966 1.5843 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7809 -0.0988 0.7054 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3362 -1.3482 0.6560 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3528 2.0131 2.3890 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7307 -4.2089 1.8494 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1933 -3.7810 1.4813 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9089 -4.5406 1.1895 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0620 -6.1080 1.7140 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5670 -1.9156 3.5608 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0156 -5.3080 4.3170 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7011 -6.9259 5.0147 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0392 -2.4658 3.3824 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0834 -6.3250 4.8995 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7730 -5.9865 3.8779 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6319 -5.3953 5.5517 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.0127 -5.5282 4.7907 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.5267 -3.8642 5.1980 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.2128 -2.9377 1.6783 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0490 -2.3172 3.3394 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.8208 -2.7683 2.3955 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2966 -4.4437 2.0243 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4358 3.8603 3.0396 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3956 6.3203 2.6210 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2096 5.6543 4.0570 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6755 7.3487 0.8324 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7432 8.5314 0.2089 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7521 8.3253 1.6178 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6930 6.9371 3.6507 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6239 5.7581 4.2768 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 44 1 0 0 0 0 2 3 1 0 0 0 0 2 45 1 0 0 0 0 3 4 2 0 0 0 0 3 46 1 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 47 1 0 0 0 0 6 34 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 8 15 1 0 0 0 0 9 10 2 0 0 0 0 10 14 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 48 1 0 0 0 0 13 14 1 0 0 0 0 13 49 1 0 0 0 0 15 16 2 0 0 0 0 15 18 1 0 0 0 0 16 17 1 0 0 0 0 16 50 1 0 0 0 0 17 20 2 0 0 0 0 17 51 1 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 52 1 0 0 0 0 22 23 2 0 0 0 0 22 25 1 0 0 0 0 23 24 1 0 0 0 0 23 53 1 0 0 0 0 24 27 2 0 0 0 0 24 54 1 0 0 0 0 25 26 2 0 0 0 0 25 55 1 0 0 0 0 26 27 1 0 0 0 0 26 28 1 0 0 0 0 27 56 1 0 0 0 0 28 29 1 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 29 57 1 0 0 0 0 29 58 1 0 0 0 0 30 31 1 0 0 0 0 30 59 1 0 0 0 0 30 60 1 0 0 0 0 31 32 1 0 0 0 0 32 33 1 0 0 0 0 32 61 1 0 0 0 0 32 62 1 0 0 0 0 33 63 1 0 0 0 0 33 64 1 0 0 0 0 34 35 1 0 0 0 0 34 65 1 0 0 0 0 35 36 2 0 0 0 0 35 37 1 0 0 0 0 37 38 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 38 39 2 0 0 0 0 38 43 1 0 0 0 0 39 40 1 0 0 0 0 39 68 1 0 0 0 0 40 41 2 0 0 0 0 40 69 1 0 0 0 0 41 42 1 0 0 0 0 41 70 1 0 0 0 0 42 43 2 0 0 0 0 42 71 1 0 0 0 0 43 72 1 0 0 0 0 M END > 723604 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 20346655 > Bioorg. Med. Chem. Lett.|2010|20|8|2452 > 26 > 2010 > 723604 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 20346655 > Bioorg. Med. Chem. Lett.|2010|20|8|2452 > 26 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 65 70 0 0 0 0 0 0 0 0999 V2000 -0.1057 1.3245 -0.5662 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2820 2.0408 -0.3026 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4180 1.3935 0.1298 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0611 -0.0303 -0.3999 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2010 -0.7123 0.0446 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3955 0.0046 0.3073 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4765 -0.6739 0.7207 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4240 -1.9750 0.8772 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3308 -2.6843 0.6434 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2088 -2.1128 0.2323 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3010 3.3881 -0.4752 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5287 4.0614 -0.1897 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0994 -2.8510 -0.0031 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.2004 -4.2020 0.0923 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3005 -4.8571 1.2103 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1948 -6.2271 1.3132 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4167 -6.9570 0.2921 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9190 -6.2951 -0.8300 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8095 -4.9248 -0.9258 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5317 -8.4266 0.3984 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1009 -9.1299 1.3913 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2816 -9.4650 -0.8059 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.9383 -10.8818 0.1833 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2839 -10.4608 1.3466 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0911 -11.4379 2.2953 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1802 -12.7536 2.0772 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8291 -13.1629 0.9207 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2077 -12.2338 -0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3581 5.5611 -0.4403 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6725 6.2820 -0.1347 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5087 7.7219 -0.3753 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0014 1.9855 -0.9977 O 0 0 0 0 0 0 0 0 0 0 0 0 2.1670 1.1999 -1.2549 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8076 8.4175 -0.3229 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6925 9.5207 0.7499 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1624 9.7590 0.8434 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6092 8.3280 0.6294 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3196 1.9530 0.3308 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8485 -0.5732 -0.6103 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3122 -2.4909 1.2110 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3154 3.6722 -0.8360 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8000 3.8959 0.8529 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7738 -4.2918 1.9995 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5848 -6.7357 2.1825 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3924 -6.8564 -1.6220 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1981 -4.4120 -1.7932 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5976 -11.1384 3.2010 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1134 -13.4880 2.8127 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0377 -14.2104 0.7605 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7130 -12.5528 -0.9216 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5714 5.9503 0.2060 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0868 5.7266 -1.4830 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4592 5.8928 -0.7810 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9438 6.1165 0.9080 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9457 0.4637 -2.0277 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9754 1.8487 -1.5921 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4690 0.6880 -0.3413 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0283 8.8645 -1.2923 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5941 7.7143 -0.0488 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2047 10.4272 0.4272 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0874 9.1728 1.7045 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8230 10.4308 0.0550 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8861 10.1415 1.8260 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6460 7.7637 1.5612 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5884 8.3687 0.2494 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 32 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 38 1 0 0 0 0 4 5 2 0 0 0 0 4 39 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 40 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 41 1 0 0 0 0 12 42 1 0 0 0 0 13 14 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 43 1 0 0 0 0 16 17 2 0 0 0 0 16 44 1 0 0 0 0 17 18 1 0 0 0 0 17 20 1 0 0 0 0 18 19 2 0 0 0 0 18 45 1 0 0 0 0 19 46 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 27 28 2 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 29 30 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 34 1 0 0 0 0 31 37 1 0 0 0 0 32 33 1 0 0 0 0 33 55 1 0 0 0 0 33 56 1 0 0 0 0 33 57 1 0 0 0 0 34 35 1 0 0 0 0 34 58 1 0 0 0 0 34 59 1 0 0 0 0 35 36 1 0 0 0 0 35 60 1 0 0 0 0 35 61 1 0 0 0 0 36 37 1 0 0 0 0 36 62 1 0 0 0 0 36 63 1 0 0 0 0 37 64 1 0 0 0 0 37 65 1 0 0 0 0 M END > 691669 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 25 > 2009 > 691669 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 25 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 42 45 0 0 0 999 V2000 -0.0165 1.3634 0.0095 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2579 1.7989 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1264 0.7032 -0.0145 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4128 -0.4041 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9344 -1.7858 -0.0267 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6891 -3.0042 0.0427 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4550 -3.4699 0.0281 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4093 -2.6695 0.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5770 -1.2825 0.0301 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8770 -0.7586 0.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9400 -1.6435 0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4074 -0.3858 0.0233 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1670 -0.9003 0.0088 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2614 -2.1275 -0.0416 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1978 -2.8701 -0.0203 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9979 -3.9648 -0.0355 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3276 -3.5074 -0.0494 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3726 -4.4202 -0.0645 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0976 -5.7761 -0.0689 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7803 -6.2267 -0.0583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7422 -5.3401 -0.0368 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1190 -6.6731 -0.0840 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7662 -8.0579 -0.0878 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.1104 0.7302 0.0550 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8991 1.9855 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5312 2.7296 0.0018 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5178 -3.6968 0.0431 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4140 -3.0886 0.0099 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.9555 -1.2761 0.0640 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5478 0.6850 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0266 -1.9711 0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0136 -1.5150 -0.0460 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3956 -4.0739 -0.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5777 -7.2876 -0.0622 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7241 -5.7004 -0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1877 -8.2879 0.8069 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1696 -8.2785 -0.9729 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6724 -8.6636 -0.1003 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1771 1.0939 -0.9703 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0406 0.9489 0.5794 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2822 1.2247 0.5627 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 26 1 0 0 0 0 2 3 1 0 0 0 0 2 27 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 14 1 0 0 0 0 6 15 1 0 0 0 0 6 16 2 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 7 28 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 29 1 0 0 0 0 10 13 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 25 1 0 0 0 0 12 30 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 32 1 0 0 0 0 15 18 1 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 34 1 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 35 1 0 0 0 0 22 36 1 0 0 0 0 23 24 1 0 0 0 0 24 37 1 0 0 0 0 24 38 1 0 0 0 0 24 39 1 0 0 0 0 25 40 1 0 0 0 0 25 41 1 0 0 0 0 25 42 1 0 0 0 0 M END > 510937 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2b > 2007 > 510937 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2b > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 45 47 0 0 0 0 0 0 0 0999 V2000 0.0715 1.4811 0.3022 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0231 6.4188 1.2136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2241 5.8128 2.4378 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3015 6.5801 3.5843 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1326 7.9509 3.5144 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1140 8.5596 2.2964 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1865 7.7988 1.1445 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2498 9.1084 5.2566 I 0 0 0 0 0 0 0 0 0 0 0 0 -0.4268 8.3930 -0.0448 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.1020 5.6445 0.0514 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.0449 4.2598 0.1346 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1880 3.5976 0.0018 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2402 2.2055 0.0866 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1559 2.1496 0.4285 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2088 3.5264 0.3443 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3938 4.1637 0.4663 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.2894 1.4435 0.6327 F 0 0 0 0 0 0 0 0 0 0 0 0 2.4202 4.3701 -0.2266 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6141 3.7449 -0.2439 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3609 5.5716 -0.3995 O 0 0 0 0 0 0 0 0 0 0 0 0 0.1222 0.0109 0.3920 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9678 -0.6651 0.5931 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.9196 -2.0627 0.6784 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.0511 -2.7645 0.8873 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0007 -4.2270 0.9765 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1151 -2.1840 1.0018 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.8935 -4.9901 0.8683 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.2281 -6.2804 1.0013 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5623 -6.3656 1.1980 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0656 -5.0552 1.1896 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2737 -7.4451 0.9415 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1622 -7.9007 -0.4084 O 0 0 0 0 0 0 0 0 0 0 0 0 0.3555 4.7423 2.4941 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4938 6.1084 4.5367 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2454 9.6304 2.2451 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1966 6.0750 -0.8126 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1848 1.6919 -0.0145 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3951 4.2940 -0.3975 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0661 -0.5041 0.2904 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0719 -2.5252 0.5872 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1333 -7.2712 1.3395 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0962 -4.7597 1.3199 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7061 -7.1309 1.3010 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6484 -8.2544 1.5683 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4375 -8.6507 -0.5220 H 0 0 0 0 0 0 0 0 0 0 0 0 1 21 1 0 0 0 0 1 13 2 0 0 0 0 1 14 1 0 0 0 0 2 10 1 0 0 0 0 2 7 1 0 0 0 0 2 3 2 0 0 0 0 3 4 1 0 0 0 0 3 33 1 0 0 0 0 4 5 2 0 0 0 0 4 34 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 6 35 1 0 0 0 0 7 9 1 0 0 0 0 10 11 1 0 0 0 0 10 36 1 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 12 18 1 0 0 0 0 12 13 1 0 0 0 0 13 37 1 0 0 0 0 14 17 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 18 19 1 0 0 0 0 18 20 2 0 0 0 0 19 38 1 0 0 0 0 21 22 2 0 0 0 0 21 39 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 24 25 1 0 0 0 0 24 26 2 0 0 0 0 25 27 1 0 0 0 0 25 30 2 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 31 1 0 0 0 0 29 30 1 0 0 0 0 29 41 1 0 0 0 0 30 42 1 0 0 0 0 31 32 1 0 0 0 0 31 43 1 0 0 0 0 31 44 1 0 0 0 0 32 45 1 0 0 0 0 M END > 573579 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19019675 > Bioorg. Med. Chem. Lett.|2009|19|1|226 > 6c > 2009 > 573579 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19019675 > Bioorg. Med. Chem. Lett.|2009|19|1|226 > 6c > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 38 42 0 0 0 0 0 0 0 0999 V2000 -0.0078 1.3684 -0.0109 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1835 2.0866 -0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4026 1.4170 -0.0187 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4335 0.0400 -0.0352 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2391 -0.6838 -0.0392 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0166 -0.0087 -0.0270 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2688 -2.1609 -0.0574 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2243 -2.9194 -0.0624 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7317 -3.1358 -0.0828 S 0 0 0 0 0 0 0 0 0 0 0 0 1.7654 -4.6088 -0.0916 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4126 -4.2503 -0.0794 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5536 -5.2807 -0.0876 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1717 -6.5869 -0.1043 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1720 -6.9340 -0.1140 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1369 -5.9520 -0.1113 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1554 3.4811 0.0097 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1329 4.1852 0.6918 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0425 3.5513 1.4261 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9770 4.2193 2.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0678 5.5311 2.0447 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1924 5.5855 0.6211 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2023 6.2551 1.3366 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0380 7.5938 1.1089 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9634 7.8011 0.2834 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4140 6.6225 -0.0532 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9528 1.8911 0.0028 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3259 1.9773 -0.0157 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3804 -0.4794 -0.0454 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9086 -0.5657 -0.0308 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6041 -5.0299 -0.0803 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9232 -7.3626 -0.1097 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4608 -7.9746 -0.1268 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1823 -6.2226 -0.1243 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4511 3.9575 -0.4570 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6962 3.6655 2.6634 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5995 8.2937 1.4774 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6157 8.7668 -0.0527 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5562 6.4709 -0.6917 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 26 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 27 1 0 0 0 0 4 5 1 0 0 0 0 4 28 1 0 0 0 0 5 7 1 0 0 0 0 5 6 2 0 0 0 0 6 29 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 30 1 0 0 0 0 13 14 1 0 0 0 0 13 31 1 0 0 0 0 14 15 2 0 0 0 0 14 32 1 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 35 1 0 0 0 0 20 22 1 0 0 0 0 21 22 2 0 0 0 0 21 25 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 36 1 0 0 0 0 24 25 2 0 0 0 0 24 37 1 0 0 0 0 25 38 1 0 0 0 0 M END > 557496 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "10, Table 3" > 2009 > 557496 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "10, Table 3" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 41 43 0 0 0 0 0 0 0 0999 V2000 -0.0152 1.2399 -0.9710 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0621 1.5910 -1.7586 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2719 0.9180 -1.6265 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3770 -0.1158 -0.6860 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2847 -0.4623 0.1029 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0926 0.2176 -0.0426 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4893 1.0659 -2.2795 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7623 -0.6271 -0.7818 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3988 0.1872 -1.8250 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5496 0.0838 -2.2112 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3335 -1.6494 -0.0483 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7160 -1.9063 -0.1544 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7066 -0.9696 -0.3577 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9031 -1.6078 -0.4024 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6999 -2.9380 -0.2315 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3293 -3.1466 -0.0675 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2411 -0.9460 -0.6089 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6448 -4.4711 0.1521 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7666 -4.0024 -0.2155 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2672 -4.2012 1.2166 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3339 -5.2657 1.2326 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9215 -5.6097 2.3894 O 0 0 0 0 0 0 0 0 0 0 0 0 10.6601 -5.8095 0.2041 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9501 1.7702 -1.0764 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9655 2.3897 -2.4792 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3694 -1.2597 0.8263 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7577 -0.0483 0.5679 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6610 1.7203 -2.9746 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7210 -2.2518 0.6063 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5710 -0.0139 -0.4533 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6636 -0.6711 0.3575 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9140 -1.6374 -1.1162 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1136 -0.0508 -1.2176 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5838 -4.6758 1.2210 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6399 -4.4349 -0.2688 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2154 -5.2605 -0.3370 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3512 -4.9386 -0.5884 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5967 -3.6945 -0.8512 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6826 -3.2650 1.5895 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4371 -4.5091 1.8523 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6000 -6.2974 2.3496 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 24 1 0 0 0 0 2 3 1 0 0 0 0 2 25 1 0 0 0 0 3 4 2 0 0 0 0 3 7 1 0 0 0 0 4 5 1 0 0 0 0 4 8 1 0 0 0 0 5 6 2 0 0 0 0 5 26 1 0 0 0 0 6 27 1 0 0 0 0 7 9 1 0 0 0 0 7 28 1 0 0 0 0 8 11 2 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 11 12 1 0 0 0 0 11 29 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 13 14 1 0 0 0 0 13 30 1 0 0 0 0 14 15 2 0 0 0 0 14 17 1 0 0 0 0 15 16 1 0 0 0 0 15 19 1 0 0 0 0 16 18 1 0 0 0 0 17 31 1 0 0 0 0 17 32 1 0 0 0 0 17 33 1 0 0 0 0 18 34 1 0 0 0 0 18 35 1 0 0 0 0 18 36 1 0 0 0 0 19 20 1 0 0 0 0 19 37 1 0 0 0 0 19 38 1 0 0 0 0 20 21 1 0 0 0 0 20 39 1 0 0 0 0 20 40 1 0 0 0 0 21 22 1 0 0 0 0 21 23 2 0 0 0 0 22 41 1 0 0 0 0 M END > 112922 > Serine/threonine-protein kinase Aurora-C > Homo sapiens > 17850214 > Biochem. J.|2007|408|3|297 > SU 6668 > 2007 > 112922 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20403700 > Bioorg. Med. Chem.|2010|18|10|3575 > 51 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 59 63 0 0 0 999 V2000 -0.1462 1.5590 -0.5064 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1076 2.0638 -0.1503 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1625 1.2144 0.0957 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3534 0.2180 -0.6184 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6992 -0.6745 -0.3749 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9735 -0.1732 -0.0133 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0282 -1.0709 0.2306 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8233 -2.4132 0.1191 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5806 -2.9240 -0.2350 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5123 -2.0758 -0.4846 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8038 -2.6252 -0.8599 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9510 -3.9512 -1.0508 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.7562 -1.8818 -0.9973 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2584 -4.4970 -1.4237 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2870 3.4066 -0.0462 O 0 0 0 0 0 0 0 0 0 0 0 0 0.7795 4.0341 1.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2622 5.2939 3.2777 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3151 3.9863 3.1765 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1957 3.3160 2.0727 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2924 6.0497 2.3229 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8357 5.4403 1.1658 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4173 6.2354 0.1663 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4545 7.5910 0.3181 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9172 8.1976 1.4630 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3462 7.4481 2.4503 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9662 9.5495 1.5910 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4028 10.1095 2.7789 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0184 8.3615 -0.6500 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5485 7.6844 -1.7914 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0794 -5.8305 -2.1703 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8004 -6.9056 -1.3311 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8447 -6.1092 -0.5098 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0819 -4.8082 -0.1569 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9626 2.2415 -0.6909 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1284 1.6119 0.3701 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3278 -0.1574 -0.8942 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0026 -0.6955 0.5064 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6414 -3.0923 0.3091 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4453 -3.9924 -0.3170 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1912 -4.5442 -0.9413 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7939 -3.7858 -2.0527 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7723 3.4162 3.9717 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1374 2.2390 2.0175 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8338 5.7767 -0.7184 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0637 7.9283 3.3265 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9247 9.7137 3.6501 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5076 11.1942 2.7543 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6537 9.8478 2.8383 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9674 8.4139 -2.4845 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3302 6.9943 -1.4739 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7521 7.1285 -2.2863 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5288 -5.7668 -3.1613 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0198 -6.0716 -2.2552 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2958 -7.6275 -1.9804 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0960 -7.4078 -0.6680 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7249 -5.8892 -1.1139 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1209 -6.6523 0.3939 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4229 -4.9717 0.6959 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7826 -3.9996 0.0508 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 34 1 0 0 0 0 2 3 1 0 0 0 0 2 15 1 0 0 0 0 3 6 2 0 0 0 0 3 35 1 0 0 0 0 4 5 2 0 0 0 0 4 36 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 37 1 0 0 0 0 8 9 1 0 0 0 0 8 38 1 0 0 0 0 9 10 2 0 0 0 0 9 39 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 14 1 0 0 0 0 12 40 1 0 0 0 0 14 30 1 0 0 0 0 14 33 1 0 0 0 0 14 41 1 0 0 0 0 15 16 1 0 0 0 0 16 21 2 0 0 0 0 16 19 1 0 0 0 0 17 20 2 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 42 1 0 0 0 0 19 43 1 0 0 0 0 20 21 1 0 0 0 0 20 25 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 2 0 0 0 0 24 26 1 0 0 0 0 25 45 1 0 0 0 0 26 27 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 28 29 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 31 32 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 32 33 1 0 0 0 0 32 56 1 0 0 0 0 32 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > 540565 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 11 > 2008 > 540565 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 11 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 49 53 0 0 0 0 0 0 0 0999 V2000 -0.0662 1.4890 0.1050 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0907 0.1219 0.4137 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0763 -0.5610 0.6764 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1153 2.1730 0.0577 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3156 1.5021 0.3202 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2988 0.1202 0.6334 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4637 -0.4992 0.8804 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5937 0.1654 0.8320 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6581 1.4556 0.5441 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5665 2.1633 0.2840 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2782 -0.5366 0.4547 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.2375 -1.9286 0.7751 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2311 2.1403 -0.1558 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1408 3.5328 -0.4639 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6486 3.5082 -0.0153 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8744 4.1716 0.0802 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8970 3.6316 0.8497 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1080 4.2833 0.9468 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3089 5.4883 0.2714 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2814 6.0321 -0.5031 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0716 5.3727 -0.6021 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6062 6.1878 0.3759 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6157 5.7703 1.0637 N 0 0 0 0 0 0 0 0 0 0 0 0 8.9974 7.7033 -0.4250 S 0 0 0 0 0 0 0 0 0 0 0 0 10.6147 7.6695 0.2729 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7340 6.5161 1.0568 C 0 0 0 0 0 0 0 0 0 0 0 0 11.9591 6.2801 1.7193 C 0 0 0 0 0 0 0 0 0 0 0 0 12.9930 7.1563 1.5941 C 0 0 0 0 0 0 0 0 0 0 0 0 12.8664 8.2980 0.8152 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6849 8.5546 0.1567 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0696 5.8993 -1.3557 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0486 -1.6141 0.9141 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1234 3.2262 -0.1811 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5126 -0.3640 1.0365 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2503 -2.3315 0.7740 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6364 -2.4547 0.0335 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7947 -2.0615 1.7622 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1390 3.9291 -0.6506 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6908 4.0623 0.3758 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5239 3.6691 -1.3521 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8551 3.9929 -0.2919 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7430 2.6995 1.3732 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9015 3.8616 1.5460 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4339 6.9644 -1.0265 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0761 5.3974 2.3304 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9230 6.9610 2.1073 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6948 8.9850 0.7254 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5868 9.4433 -0.4491 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0779 5.6104 -2.2785 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 32 1 0 0 0 0 4 5 2 0 0 0 0 4 33 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 34 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 12 37 1 0 0 0 0 13 14 1 0 0 0 0 14 38 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 15 16 1 0 0 0 0 15 41 1 0 0 0 0 16 17 2 0 0 0 0 16 21 1 0 0 0 0 17 18 1 0 0 0 0 17 42 1 0 0 0 0 18 19 2 0 0 0 0 18 43 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 44 1 0 0 0 0 21 31 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 28 46 1 0 0 0 0 29 30 2 0 0 0 0 29 47 1 0 0 0 0 30 48 1 0 0 0 0 31 49 1 0 0 0 0 M END > 691784 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 3 > 2009 > 691784 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 3 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 -0.0967 1.3159 -0.6269 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2895 2.0283 -0.4400 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4441 1.3798 -0.0613 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0541 -0.0363 -0.4374 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2126 -0.7183 -0.0466 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4234 -0.0058 0.1384 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5224 -0.6854 0.5019 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4723 -1.9839 0.6813 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3648 -2.6905 0.5201 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2230 -2.1180 0.1622 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3066 3.3727 -0.6340 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5521 4.0422 -0.4273 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0290 1.9774 -1.0065 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2115 1.1954 -1.1866 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0753 -2.8677 -0.0027 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1306 -4.2583 0.0941 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2701 -4.9382 -0.3231 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3256 -6.3117 -0.2341 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2362 -7.0215 0.2757 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9064 -6.3359 0.6938 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9559 -4.9624 0.6023 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2927 -8.4947 0.3730 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6575 -9.2406 0.8281 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.6666 -9.4810 -0.1075 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.8037 -10.9399 0.3728 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4553 -10.5691 0.8590 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3276 -11.5868 1.3049 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9470 -12.8928 1.2596 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3031 -13.2521 0.7756 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1757 -12.2825 0.3356 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3764 5.5390 -0.6911 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7098 6.2558 -0.4698 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5412 7.6930 -0.7231 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8407 8.3785 -0.7533 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6176 9.8811 -0.9396 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8742 10.1126 -2.1859 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5747 9.4271 -2.1557 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7978 7.9244 -1.9694 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7055 11.5497 -2.4392 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3588 1.9362 0.0810 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8687 -0.5766 -0.5887 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3751 -2.4993 0.9739 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2994 3.6382 -1.1102 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8798 3.8905 0.6011 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4651 0.6993 -0.2498 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0375 0.4463 -1.9590 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0337 1.8442 -1.4884 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7695 -2.4276 -0.1858 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1124 -4.3887 -0.7169 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2107 -6.8390 -0.5578 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7503 -6.8821 1.0888 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8393 -4.4317 0.9255 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3046 -11.3265 1.6845 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6261 -13.6587 1.6041 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5916 -14.2924 0.7447 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1484 -12.5626 -0.0410 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6290 5.9430 -0.0082 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0486 5.6907 -1.7195 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4572 5.8518 -1.1527 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0376 6.1041 0.5586 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4356 7.9937 -1.5817 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3666 8.2025 0.1851 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5811 10.3882 -0.9913 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0459 10.2710 -0.0974 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0488 9.6031 -3.0941 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9798 9.8118 -1.3273 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8343 7.4174 -1.9177 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3695 7.5345 -2.8116 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1545 12.0017 -1.6145 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1523 11.6926 -3.3674 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6847 12.0211 -2.5236 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 40 1 0 0 0 0 4 5 2 0 0 0 0 4 41 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 42 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 43 1 0 0 0 0 12 44 1 0 0 0 0 13 14 1 0 0 0 0 14 45 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 15 16 1 0 0 0 0 15 48 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 49 1 0 0 0 0 18 19 2 0 0 0 0 18 50 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 51 1 0 0 0 0 21 52 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 M END > 691692 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 5 > 2009 > 691692 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 5 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 72 77 0 0 0 0 0 0 0 0999 V2000 0.0861 1.3580 0.0982 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0714 2.0780 0.4252 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2501 1.4241 0.7081 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0695 -0.0072 0.0529 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1146 -0.6961 0.3410 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2899 0.0251 0.6675 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4145 -0.6592 0.9295 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4214 -1.9702 0.8833 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3488 -2.6854 0.5838 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1861 -2.1092 0.3076 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0299 3.4353 0.4638 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2417 4.1120 0.8038 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2367 2.0261 -0.1823 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3808 1.2368 -0.5143 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0756 -2.8676 -0.0036 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1310 -4.2601 0.0944 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1098 -4.8620 0.8748 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1710 -6.2361 0.9699 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2484 -7.0257 0.2813 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7361 -6.4215 -0.5041 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7936 -5.0444 -0.5965 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3132 -8.4983 0.3833 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1814 -9.1517 1.0802 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7765 -9.6104 -0.4334 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.0745 -10.9823 0.2717 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1158 -10.4943 1.0694 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9393 -11.4258 1.7398 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7200 -12.7627 1.6089 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6849 -13.2385 0.8163 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1340 -12.3550 0.1498 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0015 5.6230 0.7963 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2990 6.3474 1.1603 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0684 7.7982 1.1531 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.3360 8.5335 1.2634 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0473 10.0350 1.3325 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3070 10.4446 0.1309 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.0394 9.7093 0.0206 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3281 8.2078 -0.0484 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0764 11.8954 0.1237 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7506 -4.4533 -1.3607 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.1372 1.9863 0.9598 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9655 -0.5525 -0.2044 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3434 -2.4891 1.0997 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0135 3.8631 0.0753 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5655 3.8004 1.7969 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6211 0.5768 0.3193 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1655 0.6395 -1.4002 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2284 1.8921 -0.7150 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7432 -2.4337 -0.2903 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8240 -4.2525 1.4084 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9327 -6.7017 1.5776 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4509 -7.0299 -1.0382 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7494 -11.0743 2.3616 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3589 -13.4616 2.1283 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5219 -14.3019 0.7220 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9396 -12.7258 -0.4666 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2298 5.8718 1.5247 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6778 5.9345 -0.1968 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0708 6.0986 0.4319 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6228 6.0359 2.1534 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9560 8.3221 0.3923 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.8597 8.2220 2.1672 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9875 10.5840 1.3851 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4501 10.2501 2.2185 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5157 10.0208 -0.8831 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4194 9.9207 0.8918 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3879 7.6588 -0.1011 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9253 7.9927 -0.9345 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4971 12.1755 1.0036 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5267 12.1714 -0.7762 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0341 12.4156 0.1384 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4854 -4.3065 -2.2790 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 15 16 1 0 0 0 0 15 49 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 51 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 52 1 0 0 0 0 21 40 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 40 72 1 0 0 0 0 M END > 691665 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 7 > 2009 > 691665 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 7 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 52 55 0 0 0 999 V2000 0.2207 1.0332 0.1701 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2352 0.5695 1.4124 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4105 0.9081 2.5664 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3226 1.8346 0.0880 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0058 2.1977 1.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5475 1.7313 2.5146 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1975 2.0762 3.6325 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2613 2.8441 3.6010 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7709 3.3411 2.4080 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1502 3.0252 1.2123 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4382 0.6765 -0.9646 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.3347 -0.2271 1.4682 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7512 -0.6681 2.7621 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0754 1.1813 -2.1989 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6255 3.4956 0.0327 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7909 4.1940 0.0475 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7650 5.5528 -0.0933 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1842 4.1876 0.2310 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0012 3.5139 0.2122 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1937 5.5817 0.0833 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9696 6.2756 -0.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9794 7.6742 -0.2209 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1597 8.3553 -0.2037 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3701 7.6922 -0.0468 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4077 6.3130 0.0970 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6964 5.6156 0.2631 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8512 6.3063 0.1867 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7171 4.4173 0.4691 O 0 0 0 0 0 0 0 0 0 0 0 0 12.1314 5.6135 0.3518 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2765 6.6198 0.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0481 0.5444 3.5166 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6672 2.1867 -0.8730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7541 3.0968 4.5282 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6478 3.9715 2.4138 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9494 -1.2428 3.2256 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9843 0.1968 3.3832 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6377 -1.2948 2.6644 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5411 0.8221 -3.0229 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0588 2.2710 -2.1809 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1002 0.8357 -2.3344 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8238 6.0682 -0.2159 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1123 3.6494 0.3550 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9977 2.4400 0.3265 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0498 8.2098 -0.3448 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1538 9.4296 -0.3143 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2912 8.2561 -0.0370 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8347 7.2622 0.0225 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1680 5.1474 1.3365 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2316 4.8472 -0.4169 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2399 7.0858 -0.7636 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1763 7.3861 0.9897 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2290 6.1043 0.3439 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 31 1 0 0 0 0 4 5 2 0 0 0 0 4 32 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 33 1 0 0 0 0 9 10 2 0 0 0 0 9 34 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 35 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 14 38 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 41 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 42 1 0 0 0 0 19 43 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 44 1 0 0 0 0 23 24 2 0 0 0 0 23 45 1 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 47 1 0 0 0 0 29 30 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 M END > 540609 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 15 > 2008 > 540609 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 15 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 34 37 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3848 1.9334 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1692 0.8418 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3452 -0.3800 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6773 -1.7483 -0.0226 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6616 -2.7018 -0.0174 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6613 -2.3060 -0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9893 -0.9597 0.0060 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0936 -2.1701 -0.0389 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5285 -3.4679 -0.0549 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1222 -1.3575 -0.0459 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3847 0.8599 -0.0260 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2700 -2.0757 -0.0612 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9100 -3.4353 -0.0727 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8944 -4.4140 -0.0933 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2237 -4.0517 -0.1078 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5887 -2.7076 -0.1019 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6239 -1.7216 -0.0737 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9044 -2.3649 -0.1159 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8529 -3.4335 -0.1363 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5141 1.8673 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5311 1.8769 -0.8764 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6950 2.8525 0.0009 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9094 -3.7530 -0.0252 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4445 -3.0497 0.0010 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0265 -0.6588 0.0176 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9713 -4.2619 -0.0537 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6186 -5.4582 -0.0976 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9876 -4.8149 -0.1235 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9123 -0.6808 -0.0693 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7211 -4.0533 0.7506 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6986 -4.0394 -1.0292 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8626 -3.0230 -0.1459 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 22 1 0 0 0 0 1 23 1 0 0 0 0 2 3 1 0 0 0 0 2 24 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 5 2 0 0 0 0 4 9 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 25 1 0 0 0 0 8 9 2 0 0 0 0 8 26 1 0 0 0 0 9 27 1 0 0 0 0 10 12 2 0 0 0 0 10 11 1 0 0 0 0 11 15 1 0 0 0 0 11 28 1 0 0 0 0 12 14 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 29 1 0 0 0 0 17 18 1 0 0 0 0 17 30 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 31 1 0 0 0 0 20 21 1 0 0 0 0 21 32 1 0 0 0 0 21 33 1 0 0 0 0 21 34 1 0 0 0 0 M END > 592717 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 19a > 2008 > 592717 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 19a > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 49 53 0 0 0 0 0 0 0 0999 V2000 2.2286 1.4228 -0.6228 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1772 2.0906 -0.0082 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1460 1.3724 0.5910 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1624 -0.0042 0.5782 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2158 -0.6841 -0.0376 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2535 0.0394 -0.6410 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2363 -2.1598 -0.0524 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3309 -2.9155 0.4743 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4926 -3.1394 -0.7961 S 0 0 0 0 0 0 0 0 0 0 0 0 1.6514 -4.6096 -0.3116 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4867 -4.2473 0.3745 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3516 -5.2748 0.8606 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0287 -6.5824 0.6633 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1282 -6.9332 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9646 -5.9536 -0.5044 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1547 3.4852 0.0092 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3360 4.1936 0.1055 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4915 3.5689 0.2909 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6310 4.2355 0.3844 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7016 5.5428 0.3022 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3471 5.6050 0.0032 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5914 6.2737 0.1151 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6332 7.6702 0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4643 8.3730 -0.1682 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2362 7.7051 -0.2722 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1742 6.3423 -0.1982 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5018 9.7280 -0.2572 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0955 8.4207 -0.4612 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7830 10.3504 -0.1430 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1244 7.6830 -0.5594 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2802 -0.6151 -1.2417 O 0 0 0 0 0 0 0 0 0 0 0 0 3.0245 1.9834 -1.0905 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6691 1.8967 1.0675 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6388 -0.5582 1.0446 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2560 -5.0210 1.3936 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6801 -7.3559 1.0424 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3723 -7.9747 -0.1670 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8649 -6.2272 -1.0346 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3092 3.9574 -0.0463 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5437 3.6782 0.5356 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5751 8.1926 0.1036 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2230 5.8373 -0.2796 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2195 10.1084 0.8260 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4357 9.9866 -0.9366 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6712 11.4311 -0.2314 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9551 8.3728 -0.7087 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0666 6.9959 -1.4036 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2821 7.1177 0.3591 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1325 -0.8027 -2.1788 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 32 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 33 1 0 0 0 0 4 5 1 0 0 0 0 4 34 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 31 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 35 1 0 0 0 0 13 14 1 0 0 0 0 13 36 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 16 39 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 40 1 0 0 0 0 20 22 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 25 2 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 28 1 0 0 0 0 26 42 1 0 0 0 0 27 29 1 0 0 0 0 28 30 1 0 0 0 0 29 43 1 0 0 0 0 29 44 1 0 0 0 0 29 45 1 0 0 0 0 30 46 1 0 0 0 0 30 47 1 0 0 0 0 30 48 1 0 0 0 0 31 49 1 0 0 0 0 M END > 557762 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "27, Table 4" > 2009 > 557762 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "27, Table 4" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 53 56 0 0 0 0 0 0 0 0999 V2000 -1.3697 1.6588 -1.6278 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1851 2.1778 -1.3144 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9372 1.3596 -1.1874 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7966 -0.0150 -1.3945 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4738 -0.5107 -1.7222 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5330 0.3662 -1.8290 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9559 -0.9226 -1.2719 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2428 -0.5401 -0.9554 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9256 -2.2695 -1.4469 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2339 -2.7520 -1.2343 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0412 -1.6456 -0.9272 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3454 -1.8402 -0.6794 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8837 -3.0244 -0.7154 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1813 -4.1486 -1.0028 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8562 -4.0740 -1.2693 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2067 -5.0717 -1.5299 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.0579 3.6296 -1.1002 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1350 4.4233 -1.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0079 5.8750 -1.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1274 6.7031 -1.1319 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0034 8.0604 -0.9306 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7686 8.6065 -0.6037 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3468 7.7878 -0.4787 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2316 6.4286 -0.6720 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6513 9.9452 -0.4062 O 0 0 0 0 0 0 0 0 0 0 0 0 0.6470 10.4405 -0.0728 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5824 11.9582 0.1101 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2611 12.2761 1.2701 N 0 0 0 0 0 0 0 0 0 0 0 0 0.4511 12.0110 2.5273 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7306 13.6669 1.2142 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8985 1.7814 -0.9338 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6209 -1.5674 -1.8898 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5126 -0.0125 -2.0809 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5333 0.3689 -0.7814 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0592 -2.8618 -1.7014 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9394 -3.1163 -0.5069 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6297 -5.0086 -1.0169 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9013 4.0559 -0.8460 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0942 3.9969 -1.4751 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0877 6.2794 -1.3862 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8676 8.7009 -1.0273 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3049 8.2170 -0.2252 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0992 5.7929 -0.5743 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9858 9.9770 0.8537 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3445 10.2007 -0.8753 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5872 12.3475 0.2739 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1573 12.4141 -0.7841 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3513 12.6241 2.5711 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1960 12.2549 3.3698 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7265 10.9574 2.5736 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3038 13.8204 0.2999 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3628 13.8720 2.0781 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1264 14.3404 1.2230 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 17 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 31 1 0 0 0 0 4 5 1 0 0 0 0 4 7 1 0 0 0 0 5 6 2 0 0 0 0 5 32 1 0 0 0 0 6 33 1 0 0 0 0 7 8 1 0 0 0 0 7 9 2 0 0 0 0 8 11 1 0 0 0 0 8 34 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 36 1 0 0 0 0 14 15 1 0 0 0 0 14 37 1 0 0 0 0 15 16 2 0 0 0 0 17 18 2 0 0 0 0 17 38 1 0 0 0 0 18 19 1 0 0 0 0 18 39 1 0 0 0 0 19 20 2 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 20 40 1 0 0 0 0 21 22 2 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 2 0 0 0 0 23 42 1 0 0 0 0 24 43 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 27 28 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 28 30 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 M END > 552550 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18945615 > Bioorg. Med. Chem. Lett.|2008|18|23|6142 > 17 > 2008 > 552550 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18945615 > Bioorg. Med. Chem. Lett.|2008|18|23|6142 > 17 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 46 49 0 0 0 0 0 0 0 0999 V2000 0.7877 1.3972 2.1857 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9312 0.0317 2.3303 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8251 -0.6092 1.5909 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5813 0.0397 0.7171 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4791 1.3481 0.5447 N 0 0 0 0 0 0 0 0 0 0 0 0 1.6005 2.0589 1.2540 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5029 -0.6697 -0.0350 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5469 -2.0676 0.0475 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3776 -2.7881 0.2521 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4202 -4.1662 0.3277 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6323 -4.8315 0.1992 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8017 -4.1108 -0.0054 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7590 -2.7328 -0.0810 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4868 3.5155 1.0621 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3828 4.5904 1.9163 S 0 0 0 0 0 0 0 0 0 0 0 0 0.9918 5.9281 1.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9194 5.5434 0.2179 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2147 4.2633 0.2042 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2681 3.6771 -0.7001 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5595 7.2321 1.1938 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6756 -6.2282 0.2763 N 0 0 0 0 0 0 0 0 0 0 0 0 5.0507 -6.7225 0.1150 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0606 -8.2460 0.2653 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1636 -8.8200 -0.6892 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8152 -8.3611 -0.5605 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7825 -6.8388 -0.7192 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0635 1.9422 2.7730 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3213 -0.5088 3.0390 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1178 -0.1987 -0.6188 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4350 -2.2707 0.3524 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5108 -4.7266 0.4872 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7444 -4.6282 -0.1057 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6683 -2.1723 -0.2404 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2324 3.6922 -0.1921 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0037 2.6490 -0.9471 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3302 4.2662 -1.6151 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1399 7.4406 1.8327 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9555 7.9388 0.6603 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4211 -6.4519 -0.8737 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6893 -6.2773 0.8780 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0684 -8.6225 0.0900 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7412 -8.5145 1.2723 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1989 -8.8209 -1.3331 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4304 -8.6330 0.4225 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7654 -6.4785 -0.5651 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1167 -6.5700 -1.7213 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 27 1 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 14 1 0 0 0 0 7 8 1 0 0 0 0 7 29 1 0 0 0 0 8 13 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 30 1 0 0 0 0 10 11 2 0 0 0 0 10 31 1 0 0 0 0 11 21 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 32 1 0 0 0 0 13 33 1 0 0 0 0 14 15 1 0 0 0 0 14 18 2 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 1 0 0 0 0 19 34 1 0 0 0 0 19 35 1 0 0 0 0 19 36 1 0 0 0 0 20 37 1 0 0 0 0 20 38 1 0 0 0 0 21 22 1 0 0 0 0 21 26 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 M END > 620120 > Serine/threonine-protein kinase Aurora-C > Homo sapiens > 19320489 > J. Med. Chem.|2009|52|9|2629 > "13, CYC-116" > 2009 > 620120 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19320489 > J. Med. Chem.|2009|52|9|2629 > "13, CYC-116" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 40 43 0 0 0 999 V2000 -0.0165 1.3634 0.0095 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2579 1.7989 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1264 0.7032 -0.0145 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4128 -0.4041 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9343 -1.7858 -0.0260 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6850 -3.0259 0.0426 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4481 -3.4785 0.0280 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4076 -2.6704 0.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5772 -1.2827 0.0301 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8741 -0.7581 0.0457 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9472 -1.6534 0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4073 -0.3859 0.0233 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1671 -0.9003 0.0088 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2614 -2.1275 -0.0400 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1977 -2.8701 -0.0196 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9980 -3.9648 -0.0290 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3277 -3.5074 -0.0422 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3727 -4.4203 -0.0546 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0977 -5.7762 -0.0540 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7804 -6.2268 -0.0413 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7422 -5.3402 -0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1191 -6.6733 -0.0661 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7664 -8.0580 -0.0647 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.2955 -1.1714 0.0675 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.3651 -0.7890 0.0797 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.8991 1.9855 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5312 2.7296 0.0016 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5080 -3.7253 0.0429 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4106 -3.0854 0.0095 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0414 0.3089 0.0527 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5477 0.6849 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0266 -1.9711 0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0135 -1.5150 -0.0471 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3956 -4.0740 -0.0652 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5779 -7.2877 -0.0417 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7241 -5.7004 -0.0173 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6725 -8.6638 -0.0751 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1881 -8.2848 0.8311 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1695 -8.2819 -0.9488 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 27 1 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 4 6 1 0 0 0 0 5 14 1 0 0 0 0 6 15 1 0 0 0 0 6 16 2 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 7 29 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 30 1 0 0 0 0 10 13 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 31 1 0 0 0 0 12 25 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 33 1 0 0 0 0 15 18 1 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 35 1 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 36 1 0 0 0 0 22 37 1 0 0 0 0 23 24 1 0 0 0 0 24 38 1 0 0 0 0 24 39 1 0 0 0 0 24 40 1 0 0 0 0 25 26 3 0 0 0 0 M END > 510940 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2d > 2007 > 510940 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2d > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 41 45 0 0 0 0 0 0 0 0999 V2000 -0.0079 1.3796 0.0291 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0051 -0.0091 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2147 -0.6982 -0.0079 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4054 -0.0070 -0.0074 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4018 1.3897 0.0114 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1838 2.0829 0.0298 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6768 2.1332 0.0125 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8481 1.5893 -0.0030 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8174 3.8857 0.0275 S 0 0 0 0 0 0 0 0 0 0 0 0 5.5744 3.7579 0.0188 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9194 2.4018 0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2895 2.0591 -0.0137 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2451 3.0285 -0.0072 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8947 4.3710 0.0133 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5670 4.7360 0.0232 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1975 -0.7157 0.0102 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2987 -1.9103 -0.6832 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2967 -2.3436 -1.4411 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3842 -3.4816 -2.1054 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4544 -4.2466 -2.0588 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4612 -2.6954 -0.5972 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5069 -3.8952 -1.3272 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7364 -4.4474 -1.0706 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.3947 -3.6043 -0.2258 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6419 -2.5808 0.0567 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1731 3.4404 0.0487 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.1051 4.0790 0.0667 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9482 1.9107 0.0387 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2190 -1.7781 -0.0221 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3419 -0.5446 -0.0212 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5814 1.0194 -0.0294 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2884 2.7494 -0.0179 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6633 5.1297 0.0182 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2948 5.7810 0.0337 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9629 -0.3703 0.4957 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4536 -3.7962 -2.7099 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0751 -5.2841 -1.4256 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3908 -3.7658 0.1590 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0293 5.1606 0.0807 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6662 3.7941 -0.8232 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6534 3.7695 0.9565 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 28 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 29 1 0 0 0 0 4 5 1 0 0 0 0 4 30 1 0 0 0 0 5 7 1 0 0 0 0 5 6 2 0 0 0 0 6 26 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 31 1 0 0 0 0 13 14 1 0 0 0 0 13 32 1 0 0 0 0 14 15 2 0 0 0 0 14 33 1 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 16 35 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 36 1 0 0 0 0 20 22 1 0 0 0 0 21 22 2 0 0 0 0 21 25 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 37 1 0 0 0 0 24 25 2 0 0 0 0 24 38 1 0 0 0 0 26 27 1 0 0 0 0 27 39 1 0 0 0 0 27 40 1 0 0 0 0 27 41 1 0 0 0 0 M END > 557560 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "15, Table 3" > 2009 > 557560 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "15, Table 3" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 59 63 0 0 0 0 0 0 0 0999 V2000 3.3625 1.3362 -3.6060 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1326 0.0446 -3.5727 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1957 -0.6804 -2.3894 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5085 -0.0357 -1.2056 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6702 2.0231 -2.4994 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7541 1.3550 -1.2535 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0774 2.0773 -0.0951 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3087 3.4199 -0.1787 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2268 4.0842 -1.4108 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9128 3.4057 -2.5530 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6226 4.1201 0.9439 O 0 0 0 0 0 0 0 0 0 0 0 0 4.6905 3.3864 2.1683 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4627 5.4212 -1.4686 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3644 6.0424 -2.7518 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5769 -0.7175 -0.0355 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4362 -2.0684 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5479 -2.8679 -0.2555 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0109 -3.9906 0.0359 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1712 -2.6368 0.0721 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1235 -4.8192 -0.1408 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4034 -4.2523 -0.2902 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2830 -5.2926 -0.4440 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5797 -6.5004 -0.3940 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3059 -6.2698 -0.2169 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7299 -5.1601 -0.6311 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2985 -7.2346 -0.1175 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6078 -8.5434 -0.2054 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7627 -8.8853 -0.3711 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5431 -9.5632 -0.1003 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2162 -9.1742 0.0900 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7729 -10.1312 0.1868 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4520 -11.4738 0.0957 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8616 -11.8663 -0.0929 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8594 -10.9196 -0.1967 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2019 -13.3311 -0.1905 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0341 -14.0908 -0.0625 F 0 0 0 0 0 0 0 0 0 0 0 0 1.7934 -13.5908 -1.4315 F 0 0 0 0 0 0 0 0 0 0 0 0 2.0942 -13.6717 0.8317 F 0 0 0 0 0 0 0 0 0 0 0 0 2.8872 -0.4689 -4.4906 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0011 -1.7427 -2.3932 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1426 1.5736 0.8581 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8528 3.9300 -3.4953 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7230 2.9269 2.3707 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4512 2.6102 2.0851 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9491 4.0626 2.9832 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0853 5.5881 -3.4316 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3573 5.9054 -3.1456 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5756 7.1075 -2.6570 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5247 -2.4213 -0.3693 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0276 -4.4222 0.1508 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3113 -1.9995 0.2165 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2237 -5.1637 0.3407 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0970 -5.9948 -1.2282 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9456 -4.2232 -1.1448 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3770 -6.9619 0.0147 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0356 -8.1264 0.1616 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8000 -9.8316 0.3344 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2300 -12.2190 0.1724 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8841 -11.2273 -0.3438 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 2 3 1 0 0 0 0 2 39 1 0 0 0 0 3 4 2 0 0 0 0 3 40 1 0 0 0 0 4 6 1 0 0 0 0 4 15 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 41 1 0 0 0 0 8 9 2 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 9 13 1 0 0 0 0 10 42 1 0 0 0 0 11 12 1 0 0 0 0 12 43 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 15 16 1 0 0 0 0 16 19 1 0 0 0 0 16 17 2 0 0 0 0 17 21 1 0 0 0 0 17 49 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 50 1 0 0 0 0 19 51 1 0 0 0 0 20 21 2 0 0 0 0 20 24 1 0 0 0 0 21 22 1 0 0 0 0 22 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 2 0 0 0 0 24 26 1 0 0 0 0 25 52 1 0 0 0 0 25 53 1 0 0 0 0 25 54 1 0 0 0 0 26 27 1 0 0 0 0 26 55 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 29 30 2 0 0 0 0 29 34 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 31 32 2 0 0 0 0 31 57 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 33 34 2 0 0 0 0 33 35 1 0 0 0 0 34 59 1 0 0 0 0 35 36 1 0 0 0 0 35 37 1 0 0 0 0 35 38 1 0 0 0 0 M END > 551627 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18682324 > Bioorg. Med. Chem. Lett.|2008|18|17|4844 > 7j > 2008 > 551627 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18682324 > Bioorg. Med. Chem. Lett.|2008|18|17|4844 > 7j > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 45 48 0 0 0 999 V2000 1.7088 1.6903 -2.0673 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6422 0.3421 -2.2518 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9523 -0.5407 -1.2245 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3399 -0.0689 0.0206 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0971 2.2139 -0.8211 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4176 1.3300 0.2382 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8043 1.8509 1.4805 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8686 3.1997 1.6576 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5537 4.0756 0.6152 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1732 3.6000 -0.6081 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6671 -1.0116 1.1064 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4681 -2.3334 0.9340 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1166 -0.5964 2.1572 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6263 5.4169 0.8208 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8451 5.9600 1.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3275 7.0012 1.4985 N 0 0 0 0 0 0 0 0 0 0 0 0 6.1194 5.7120 1.3740 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9210 5.1945 1.1544 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3071 7.8663 1.4003 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0046 7.3583 1.1652 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9218 8.2414 1.0578 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1340 9.5848 1.1812 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4220 10.0888 1.4134 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4949 9.2489 1.5217 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0848 10.4434 1.0773 O 0 0 0 0 0 0 0 0 0 0 0 0 4.6057 11.4295 1.5318 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9401 11.8831 1.7677 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7978 9.8694 0.8401 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4673 2.3582 -2.8809 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3426 -0.0474 -3.2135 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8906 -1.6050 -1.3974 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0500 1.1851 2.2945 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1666 3.5976 2.6163 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9320 4.2862 -1.4065 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1096 -2.6646 0.0957 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6833 -2.9535 1.6482 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9628 5.0427 1.4585 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9266 7.8622 0.8784 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4819 9.6492 1.7005 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9464 12.9706 1.8418 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3107 11.4534 2.6984 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5810 11.5714 0.9430 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0522 10.6621 0.7786 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8151 9.3133 -0.0973 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5444 9.1949 1.6580 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 29 1 0 0 0 0 2 3 1 0 0 0 0 2 30 1 0 0 0 0 3 4 2 0 0 0 0 3 31 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 32 1 0 0 0 0 8 9 2 0 0 0 0 8 33 1 0 0 0 0 9 14 1 0 0 0 0 9 10 1 0 0 0 0 10 34 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 37 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 2 0 0 0 0 23 26 1 0 0 0 0 24 39 1 0 0 0 0 25 28 1 0 0 0 0 26 27 1 0 0 0 0 27 40 1 0 0 0 0 27 41 1 0 0 0 0 27 42 1 0 0 0 0 28 43 1 0 0 0 0 28 44 1 0 0 0 0 28 45 1 0 0 0 0 M END > 541133 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 25 > 2008 > 541133 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 25 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 54 0 0 0 0 0 0 0 0999 V2000 -0.0169 1.3941 0.0097 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1704 2.0956 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3910 1.4176 -0.0132 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4209 0.0361 -0.0213 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2324 -0.6809 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9251 -2.0311 -0.0184 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.4353 -2.1352 -0.0057 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9729 -0.9509 0.0063 N 0 0 0 0 0 0 0 0 0 0 0 0 1.8339 -3.0850 -0.0332 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8096 -4.1380 0.8072 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8068 -5.0640 0.6108 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6668 -4.7596 -0.4156 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1775 -3.2414 -1.1560 S 0 0 0 0 0 0 0 0 0 0 0 0 4.7700 -5.5460 -0.8171 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5464 -5.1439 -1.8427 N 0 0 0 0 0 0 0 0 0 0 0 0 5.0192 -6.5875 -0.2363 O 0 0 0 0 0 0 0 0 0 0 0 0 2.9309 -6.1843 1.3678 O 0 0 0 0 0 0 0 0 0 0 0 0 1.9659 -6.3774 2.4039 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2614 -7.6631 3.1323 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3372 -8.4423 2.7504 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6082 -9.6219 3.4186 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8036 -10.0218 4.4689 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7280 -9.2419 4.8515 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4597 -8.0605 4.1863 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2873 -7.2104 4.6034 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3722 -7.8197 5.6763 F 0 0 0 0 0 0 0 0 0 0 0 0 0.7430 -5.9465 4.9933 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.5973 -7.0760 3.5280 F 0 0 0 0 0 0 0 0 0 0 0 0 3.5557 2.1201 -0.0205 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7687 1.3649 -0.0362 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1523 3.4559 0.0092 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.1294 4.0876 0.0248 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9584 1.9229 0.0260 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3670 -0.4847 -0.0339 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9852 -3.0648 -0.0058 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0618 -4.2465 1.5789 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3037 -5.6837 -2.1184 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3480 -4.3146 -2.3052 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0134 -5.5437 3.1046 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9687 -6.4283 1.9668 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9659 -8.1298 1.9297 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4484 -10.2311 3.1197 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0149 -10.9436 4.9904 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0991 -9.5545 5.6720 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6203 2.0453 -0.0406 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8141 0.7319 0.8500 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7971 0.7415 -0.9298 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6738 3.7828 0.9186 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0010 5.1700 0.0290 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6911 3.7918 -0.8612 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 1 34 1 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 4 2 0 0 0 0 3 30 1 0 0 0 0 4 6 1 0 0 0 0 4 35 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 10 1 0 0 0 0 8 9 2 0 0 0 0 8 36 1 0 0 0 0 10 11 2 0 0 0 0 10 14 1 0 0 0 0 11 12 1 0 0 0 0 11 37 1 0 0 0 0 12 18 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 15 1 0 0 0 0 15 17 2 0 0 0 0 15 16 1 0 0 0 0 16 38 1 0 0 0 0 16 39 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 19 41 1 0 0 0 0 20 21 2 0 0 0 0 20 25 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 2 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 44 1 0 0 0 0 24 25 2 0 0 0 0 24 45 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 1 0 0 0 0 26 29 1 0 0 0 0 30 31 1 0 0 0 0 31 46 1 0 0 0 0 31 47 1 0 0 0 0 31 48 1 0 0 0 0 32 33 1 0 0 0 0 33 49 1 0 0 0 0 33 50 1 0 0 0 0 33 51 1 0 0 0 0 M END > 575734 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19097784 > Bioorg. Med. Chem. Lett.|2009|19|3|1018 > 2 > 2009 > 575734 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19097784 > Bioorg. Med. Chem. Lett.|2009|19|3|1018 > 2 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 32 35 0 0 0 0 0 0 0 0999 V2000 -0.0163 1.3767 0.0661 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0014 0.0025 -0.1011 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1984 -0.6792 -0.1868 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1694 2.0791 0.1484 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3810 1.4017 0.0628 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4035 0.0118 -0.1058 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7194 -0.4290 -0.1630 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5943 0.6170 -0.0386 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7927 1.8506 0.1144 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9798 0.5346 -0.0525 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8025 -0.6777 0.0350 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0937 -0.3097 -0.0204 N 0 0 0 0 0 0 0 0 0 0 0 0 6.3872 -1.8182 0.1402 O 0 0 0 0 0 0 0 0 0 0 0 0 6.9454 1.6487 -0.1651 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2217 1.0697 -0.1399 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3395 1.8914 -0.2310 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1877 3.2584 -0.3441 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9237 3.8292 -0.3684 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8010 3.0285 -0.2795 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2332 3.0710 0.2611 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3177 4.1429 0.3948 O 0 0 0 0 0 0 0 0 0 0 0 0 7.7901 5.1690 -0.4791 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.9589 1.9004 0.1277 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9297 -0.5409 -0.1648 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1997 -1.7513 -0.3165 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1562 3.1512 0.2781 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9837 -1.3554 -0.2758 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8408 -0.9271 0.0183 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3290 1.4589 -0.2128 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0612 3.8897 -0.4141 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8161 3.4712 -0.2979 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7373 5.0079 0.4984 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 23 1 0 0 0 0 2 3 1 0 0 0 0 2 24 1 0 0 0 0 3 6 2 0 0 0 0 3 25 1 0 0 0 0 4 5 2 0 0 0 0 4 26 1 0 0 0 0 5 6 1 0 0 0 0 5 9 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 27 1 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 20 2 0 0 0 0 10 11 1 0 0 0 0 10 14 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 15 1 0 0 0 0 12 28 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 29 1 0 0 0 0 17 18 1 0 0 0 0 17 30 1 0 0 0 0 18 19 2 0 0 0 0 18 22 1 0 0 0 0 19 31 1 0 0 0 0 20 21 1 0 0 0 0 21 32 1 0 0 0 0 M END > 716235 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20153646 > Bioorg. Med. Chem. Lett.|2010|20|6|2033 > 13 > 2010 > 716235 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20153646 > Bioorg. Med. Chem. Lett.|2010|20|6|2033 > 13 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 59 62 0 0 0 999 V2000 -0.3960 1.3491 0.1168 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5346 1.9993 1.3514 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5674 1.2896 2.5170 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2910 -0.0104 0.0540 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3163 -0.7641 1.2370 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4618 -0.1108 2.4851 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4863 -0.8276 3.6150 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3782 -2.1354 3.6029 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2326 -2.8475 2.4190 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2102 -2.1729 1.2110 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3715 2.0798 -1.0297 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.6372 3.3538 1.3880 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.7758 3.9593 2.6749 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2340 1.3587 -2.2558 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0694 -2.8415 0.0398 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.0621 -4.1997 0.0775 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1175 -4.8725 -0.0736 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2836 -6.2518 0.3185 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2607 -4.8913 0.2762 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0918 -6.9733 0.1611 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1258 -6.2768 -0.0347 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3214 -7.0007 -0.1872 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3063 -8.3628 -0.1466 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1220 -9.0633 0.0441 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0810 -8.3901 0.1986 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3345 -9.1401 0.4007 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3303 -10.4868 0.3457 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.3718 -8.5437 0.6170 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5756 -11.2319 0.5464 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2961 -12.7320 0.4342 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5966 -13.5102 0.6438 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3355 -14.9112 0.5390 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.4906 -15.7328 0.7199 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6739 1.8033 3.4610 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1804 -0.5026 -0.9009 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4028 -2.6730 4.5393 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1457 -3.9237 2.4408 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6782 3.5841 3.1577 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0923 3.7147 3.2870 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8473 5.0410 2.5616 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2287 2.0593 -3.0908 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7012 0.7989 -2.2452 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0698 0.6678 -2.3666 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0381 -4.3278 -0.2225 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2171 -6.7737 0.4687 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1807 -4.3388 0.3981 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2535 -6.4762 -0.3373 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2314 -8.9073 -0.2650 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1380 -10.1428 0.0720 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5028 -10.9626 0.1732 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9764 -11.0100 1.5355 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3004 -10.9396 -0.2133 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8953 -12.9539 -0.5549 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5712 -13.0243 1.1939 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9974 -13.2883 1.6329 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3214 -13.2178 -0.1159 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2089 -16.7816 0.6255 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9099 -15.5571 1.7106 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2340 -15.4866 -0.0382 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 34 1 0 0 0 0 4 5 2 0 0 0 0 4 35 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 36 1 0 0 0 0 9 10 2 0 0 0 0 9 37 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 13 40 1 0 0 0 0 14 41 1 0 0 0 0 14 42 1 0 0 0 0 14 43 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 44 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 45 1 0 0 0 0 19 46 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 47 1 0 0 0 0 23 24 2 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 50 1 0 0 0 0 29 30 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 32 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 32 33 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > 540559 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 21 > 2008 > 540559 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 21 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 50 54 0 0 0 0 0 0 0 0999 V2000 -0.0161 1.3391 0.0094 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4228 1.8079 -0.0018 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.0024 2.0449 0.0271 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3030 -0.5155 -0.0132 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2286 0.5281 -0.0150 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5807 0.2851 -0.0256 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7560 -1.8265 -0.0262 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1278 -2.0855 -0.0386 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0496 -1.0252 -0.0351 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3084 -1.5798 -0.0404 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3488 -6.2138 -0.0605 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2189 -2.9625 -0.0434 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9189 -3.3239 -0.0568 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3265 -4.6978 -0.0821 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1289 -5.7217 0.6650 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4835 -5.2378 -0.0379 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4158 -3.8363 -0.0359 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6561 -3.3702 -0.0220 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5318 -4.4602 -0.0089 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7948 -5.5889 -0.0173 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3330 -6.9965 -0.0052 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2029 -0.8372 0.0091 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6086 -1.1350 1.4540 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7076 2.6331 -1.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7308 2.6219 1.2565 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2785 1.1094 -0.0270 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0501 -2.6439 -0.0267 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1376 -1.0764 -0.0424 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6786 -7.1447 0.4007 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0813 -6.4156 -1.0978 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3282 -4.6536 0.3533 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2353 -5.0177 -1.1201 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4859 -6.5758 0.8773 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4437 -5.2877 1.6140 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5005 -4.4125 0.0038 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4472 -7.3329 1.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6395 -7.6552 -0.5277 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3018 -7.0193 -0.5043 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0128 -0.3091 -0.4942 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0006 -1.7731 -0.5117 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7987 -1.6632 1.9572 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8109 -0.1991 1.9748 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5051 -1.7549 1.4592 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4385 2.0543 -2.1419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1192 3.5502 -1.2317 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7679 2.8826 -1.2965 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7917 2.8712 1.2773 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1421 3.5392 1.2489 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4781 2.0352 2.1397 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1 0 0 0 0 1 2 1 0 0 0 0 1 4 2 0 0 0 0 2 6 1 0 0 0 0 2 25 1 0 0 0 0 2 26 1 0 0 0 0 3 5 1 0 0 0 0 3 23 1 0 0 0 0 5 6 2 0 0 0 0 5 8 1 0 0 0 0 6 7 1 0 0 0 0 7 10 2 0 0 0 0 7 27 1 0 0 0 0 8 9 2 0 0 0 0 8 28 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 11 1 0 0 0 0 11 13 1 0 0 0 0 11 29 1 0 0 0 0 12 17 1 0 0 0 0 12 16 1 0 0 0 0 12 30 1 0 0 0 0 12 31 1 0 0 0 0 13 18 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 15 16 1 0 0 0 0 15 32 1 0 0 0 0 15 33 1 0 0 0 0 16 34 1 0 0 0 0 16 35 1 0 0 0 0 17 18 1 0 0 0 0 17 21 2 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 M END > 589011 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 18630890 > J. Med. Chem.|2008|51|15|4465 > "32, AKI-001" > 2008 > 589011 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18630890 > J. Med. Chem.|2008|51|15|4465 > "32, AKI-001" > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 54 58 0 0 0 0 0 0 0 0999 V2000 -0.0158 1.3140 0.0093 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1039 2.0328 0.0024 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3495 1.4062 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4021 0.0098 -0.0208 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1928 -0.7002 -0.0131 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6978 -0.7000 -0.0375 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9397 -0.1001 -0.0461 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8585 -2.0490 -0.0408 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2449 -2.3085 -0.0519 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9010 -1.0677 -0.0550 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2424 -1.0407 -0.0653 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9529 -2.1309 -0.0725 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4050 -3.3717 -0.0697 N 0 0 0 0 0 0 0 0 0 0 0 0 6.0597 -3.5219 -0.0601 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5471 -4.6275 -0.0575 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0270 3.5041 0.0106 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1693 4.1138 0.0253 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2463 5.5856 0.0334 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4895 6.2235 0.0487 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5537 7.6012 0.0567 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3909 8.3515 0.0497 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8437 7.7267 0.0346 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9236 6.3498 0.0317 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4696 9.8564 0.0580 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4823 10.3384 1.4457 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3196 11.7986 1.4977 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3983 12.2638 2.9542 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5962 11.5805 3.7220 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4673 10.1565 3.6940 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5547 9.6699 2.2451 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2580 1.9901 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1937 -1.7802 -0.0193 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9310 -0.5479 0.0084 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1033 0.8560 -0.0462 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0700 -2.7869 -0.0354 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0294 -2.0436 -0.0806 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9789 -4.1537 -0.0751 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9328 4.0923 0.0047 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0751 3.5257 0.0311 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3978 5.6392 0.0539 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5138 8.0957 0.0682 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7470 8.3187 0.0291 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8879 5.8635 0.0203 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3953 10.2684 -0.4618 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3821 10.1753 -0.4457 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6494 12.0719 1.0801 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1126 12.2739 0.9204 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2213 13.3382 3.0031 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3864 12.0384 3.3554 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2702 9.7068 4.2781 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4957 9.8698 4.1168 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3999 8.5914 2.2133 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5377 9.9092 1.8394 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 17 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 32 1 0 0 0 0 4 5 1 0 0 0 0 4 7 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 34 1 0 0 0 0 7 8 1 0 0 0 0 7 9 2 0 0 0 0 8 11 1 0 0 0 0 8 35 1 0 0 0 0 9 10 1 0 0 0 0 9 36 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 37 1 0 0 0 0 14 15 1 0 0 0 0 14 38 1 0 0 0 0 15 16 2 0 0 0 0 17 18 2 0 0 0 0 17 39 1 0 0 0 0 18 19 1 0 0 0 0 18 40 1 0 0 0 0 19 20 2 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 20 41 1 0 0 0 0 21 22 2 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 2 0 0 0 0 23 43 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 27 1 0 0 0 0 26 31 1 0 0 0 0 27 28 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 28 29 1 0 0 0 0 28 49 1 0 0 0 0 28 50 1 0 0 0 0 29 30 1 0 0 0 0 30 31 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 M END > 552549 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18945615 > Bioorg. Med. Chem. Lett.|2008|18|23|6142 > 16 > 2008 > 552549 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18945615 > Bioorg. Med. Chem. Lett.|2008|18|23|6142 > 16 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 43 47 0 0 0 0 0 0 0 0999 V2000 -0.0255 1.3782 0.0155 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1717 2.0863 0.0106 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3852 1.4064 0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4046 0.0291 0.0069 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2042 -0.6847 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0125 0.0008 0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2215 -2.1621 0.0123 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1707 -2.9118 0.0167 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6763 -3.1494 -0.0007 S 0 0 0 0 0 0 0 0 0 0 0 0 1.6976 -4.6143 0.0008 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3479 -4.2443 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6270 -5.2666 0.0143 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2560 -6.5761 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0847 -6.9345 -0.0022 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0578 -5.9606 -0.0069 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1554 3.4813 0.0092 N 0 0 0 0 0 0 0 0 0 0 0 0 0.1591 4.1589 -0.6631 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7286 3.5073 -1.4027 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.6892 4.1453 -2.0521 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8329 5.4487 -2.0141 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0528 5.5684 -0.5778 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9892 6.2053 -1.2959 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1128 7.5990 -1.2334 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2267 8.3211 -0.4876 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8001 7.6929 0.2134 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9411 6.3366 0.1825 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3814 10.0485 -0.4119 Cl 0 0 0 0 0 0 0 0 0 0 0 0 1.7604 8.5219 1.0268 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9661 1.9088 0.0232 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3131 1.9590 0.0027 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3471 -0.4982 0.0031 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9424 -0.5485 0.0198 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6753 -5.0069 0.0225 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0140 -7.3454 0.0109 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3647 -7.9776 -0.0070 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1009 -6.2401 -0.0151 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8444 3.9749 0.4809 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3862 3.5668 -2.6402 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9040 8.0991 -1.7722 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7411 5.8603 0.7299 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3773 8.6305 2.0415 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7318 8.0283 1.0561 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8667 9.5064 0.5712 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 29 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 30 1 0 0 0 0 4 5 1 0 0 0 0 4 31 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 32 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 33 1 0 0 0 0 13 14 1 0 0 0 0 13 34 1 0 0 0 0 14 15 2 0 0 0 0 14 35 1 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 38 1 0 0 0 0 20 22 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 23 39 1 0 0 0 0 24 25 2 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 28 1 0 0 0 0 26 40 1 0 0 0 0 28 41 1 0 0 0 0 28 42 1 0 0 0 0 28 43 1 0 0 0 0 M END > 557699 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "24, Table 4" > 2009 > 557699 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "24, Table 4" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 36 38 0 0 0 0 0 0 0 0999 V2000 0.0453 1.3399 0.4970 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0877 0.0410 0.6776 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1882 -0.6736 0.5073 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3311 -0.1093 0.1383 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3494 1.2896 -0.0722 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5124 1.9647 -0.4631 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4778 3.3166 -0.6539 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2901 4.0371 -0.4628 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1331 3.3969 -0.0786 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1455 2.0110 0.1228 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4718 -0.8670 -0.0353 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2810 5.3814 -0.6585 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0407 6.0592 -0.4480 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6078 3.9712 -1.0330 O 0 0 0 0 0 0 0 0 0 0 0 0 5.7859 3.1822 -1.2110 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4075 -2.2609 0.0639 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2600 -2.9342 -0.3350 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2009 -4.3117 -0.2415 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2858 -5.0207 0.2500 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4299 -4.3508 0.6478 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4929 -2.9738 0.5559 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2264 -6.3673 0.3412 F 0 0 0 0 0 0 0 0 0 0 0 0 0.7671 -5.1544 -0.7392 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -0.8161 -0.4676 0.9791 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4323 1.4190 -0.6125 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2228 3.9596 0.0667 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3180 -0.4329 -0.2259 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2881 5.6592 -1.1275 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7158 5.9109 0.5818 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1720 7.1245 -0.6377 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0357 2.6856 -0.2735 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6084 2.4333 -1.9829 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6122 3.8260 -1.5126 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4145 -2.3817 -0.7176 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2740 -4.9051 1.0308 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3861 -2.4519 0.8662 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 10 2 0 0 0 0 2 3 2 0 0 0 0 2 24 1 0 0 0 0 3 4 1 0 0 0 0 4 5 2 0 0 0 0 4 11 1 0 0 0 0 5 6 1 0 0 0 0 5 10 1 0 0 0 0 6 7 2 0 0 0 0 6 25 1 0 0 0 0 7 8 1 0 0 0 0 7 14 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 26 1 0 0 0 0 11 16 1 0 0 0 0 11 27 1 0 0 0 0 12 13 1 0 0 0 0 13 28 1 0 0 0 0 13 29 1 0 0 0 0 13 30 1 0 0 0 0 14 15 1 0 0 0 0 15 31 1 0 0 0 0 15 32 1 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 16 21 2 0 0 0 0 17 18 2 0 0 0 0 17 34 1 0 0 0 0 18 19 1 0 0 0 0 18 23 1 0 0 0 0 19 20 2 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 20 35 1 0 0 0 0 21 36 1 0 0 0 0 M END > 188936 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > Page No1356 R27C2 > 2009 > 188936 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > Page No1356 R27C2 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 55 58 0 0 0 999 V2000 -0.2495 1.3955 0.5290 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0122 0.0698 0.1550 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2648 -0.3645 -0.1195 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7746 2.2870 0.6301 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0868 1.8778 0.3572 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3380 0.5366 -0.0222 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6556 0.1286 -0.2966 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6819 1.0192 -0.1975 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4554 2.3389 0.1737 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1726 2.7846 0.4540 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9398 4.1870 0.8464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9847 5.0198 1.0226 N 0 0 0 0 0 0 0 0 0 0 0 0 1.8051 4.5919 1.0111 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7535 6.4129 1.4125 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0526 -0.7992 0.0619 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.8749 -0.6952 -1.0113 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5387 -0.4666 -3.2121 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4604 0.2768 -3.1239 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6000 0.1927 -2.0370 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8624 -1.3491 -2.2599 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0350 -1.4937 -1.1197 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3766 -2.4206 -0.1228 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5047 -3.1758 -0.2609 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.3263 -3.0349 -1.3890 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0172 -2.1415 -2.3733 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.4445 -3.7983 -1.5036 O 0 0 0 0 0 0 0 0 0 0 0 0 -7.2415 -3.6100 -2.6746 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8356 -4.0743 0.7046 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.9584 -4.1713 1.8286 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0959 7.1351 1.5443 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8544 8.5900 1.9515 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2592 1.7181 0.7362 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4404 -1.3905 -0.4071 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5758 3.3083 0.9195 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8543 -0.8927 -0.5862 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6893 0.6935 -0.4109 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2870 3.0243 0.2454 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8899 4.6967 0.8913 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1481 6.9071 0.6527 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2306 6.4406 2.3685 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2385 0.9760 -3.9164 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7204 0.8177 -1.9921 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7495 -2.5360 0.7489 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6588 -2.0434 -3.2366 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.5865 -2.5770 -2.7171 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6445 -3.8303 -3.5597 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1012 -4.2792 -2.6405 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3375 -4.9225 2.5215 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9634 -4.4592 1.4892 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9054 -3.2062 2.3324 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7013 6.6409 2.3041 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6188 7.1074 0.5884 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2490 9.0843 1.1917 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3314 8.6178 2.9075 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8107 9.1046 2.0454 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 32 1 0 0 0 0 2 15 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 33 1 0 0 0 0 4 5 2 0 0 0 0 4 34 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 35 1 0 0 0 0 8 9 1 0 0 0 0 8 36 1 0 0 0 0 9 10 2 0 0 0 0 9 37 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 14 1 0 0 0 0 12 38 1 0 0 0 0 14 30 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 15 16 1 0 0 0 0 16 21 2 0 0 0 0 16 19 1 0 0 0 0 17 20 2 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 41 1 0 0 0 0 19 42 1 0 0 0 0 20 21 1 0 0 0 0 20 25 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 2 0 0 0 0 24 26 1 0 0 0 0 25 44 1 0 0 0 0 26 27 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 31 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > 540566 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 16 > 2008 > 540566 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324761 > J. Med. Chem.|2008|51|6|1649 > 76 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 0.0686 1.3124 0.6479 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2411 2.0582 0.4634 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4105 1.4449 0.0716 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0608 -0.0382 0.4429 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2362 -0.6857 0.0442 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4254 0.0616 -0.1441 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5387 -0.5836 -0.5260 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5221 -1.8808 -0.7201 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4357 -2.6191 -0.5571 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2825 -2.0820 -0.1811 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2237 3.4003 0.6730 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4500 4.1048 0.4680 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1572 -2.8645 -0.0144 N 0 0 0 0 0 0 0 0 0 0 0 0 0.2492 -4.2519 -0.1280 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4107 -4.9054 0.2704 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5026 -6.2757 0.1643 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4279 -7.0089 -0.3434 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7371 -6.3500 -0.7421 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8228 -4.9795 -0.6341 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5235 -8.4788 -0.4590 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4105 -9.2448 -0.9136 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9285 -9.4327 -0.0037 S 0 0 0 0 0 0 0 0 0 0 0 0 1.1010 -10.9090 -0.4932 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1724 -10.5674 -0.9626 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0216 -11.6026 -1.4124 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6065 -12.8984 -1.3876 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6594 -13.2305 -0.9197 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5105 -12.2411 -0.4755 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2362 5.5934 0.7500 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5491 6.3477 0.5306 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3438 7.7769 0.8014 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6249 8.4962 0.8332 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3631 9.9901 1.0380 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6203 10.1875 2.2906 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3392 9.4682 2.2587 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6010 7.9742 2.0539 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4151 11.6166 2.5614 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0560 -14.5218 -0.9013 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.0723 1.9394 1.0406 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2327 1.1244 1.2174 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3094 2.0270 -0.0686 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8478 -0.6038 0.5880 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4357 -2.3682 -1.0271 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2113 3.7129 1.1425 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7763 3.9737 -0.5637 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6974 -2.4496 0.1817 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2414 -4.3378 0.6629 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4049 -6.7824 0.4731 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5699 -6.9145 -1.1348 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7251 -4.4698 -0.9381 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0091 -11.3638 -1.7788 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2685 -13.6778 -1.7352 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4942 -12.4986 -0.1118 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4749 5.9852 0.0755 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9098 5.7245 1.7817 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3104 5.9558 1.2051 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8754 6.2166 -0.5011 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2340 8.1178 1.6541 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1504 8.3450 -0.1097 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3131 10.5219 1.0910 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7770 10.3744 0.2032 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8137 9.6194 3.2017 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7301 9.8465 1.4378 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6510 7.4425 2.0010 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1872 7.5899 2.8887 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8480 12.0634 1.7447 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8630 11.7342 3.4939 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3818 12.1128 2.6465 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0349 0.3713 1.9801 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0702 1.7477 1.5307 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4780 0.6325 0.2761 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 39 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 13 46 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 47 1 0 0 0 0 16 17 2 0 0 0 0 16 48 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 49 1 0 0 0 0 19 50 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 51 1 0 0 0 0 26 27 1 0 0 0 0 26 52 1 0 0 0 0 27 28 2 0 0 0 0 27 38 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 62 1 0 0 0 0 35 63 1 0 0 0 0 36 64 1 0 0 0 0 36 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 39 40 1 0 0 0 0 40 69 1 0 0 0 0 40 70 1 0 0 0 0 40 71 1 0 0 0 0 M END > 691729 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 17 > 2009 > 691729 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 17 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 49 52 0 0 0 999 V2000 0.0901 1.2819 -0.5503 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0922 -0.1010 -0.3184 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2283 -0.7422 0.0835 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2267 2.0181 -0.3791 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4087 1.3847 0.0329 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4139 -0.0119 0.2683 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5403 -0.6185 0.6613 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6561 0.0493 0.8381 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7302 1.4205 0.6280 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6044 2.1140 0.2201 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0543 1.8947 -0.9551 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.0521 -0.8123 -0.4956 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -2.2175 -0.2440 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9920 3.3054 -1.1746 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6472 3.4524 0.0069 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8516 4.0747 0.0980 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1377 4.8331 1.1979 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9995 4.5379 -0.8681 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7849 3.9263 -0.9322 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3230 5.3282 0.2439 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3829 5.4768 1.2927 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7099 6.2651 2.4100 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9236 6.8809 2.4810 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8583 6.7473 1.4622 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5780 5.9797 0.3413 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5750 5.8422 -0.7366 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7299 6.5346 -0.6786 N 0 0 0 0 0 0 0 0 0 0 0 0 9.3552 5.1041 -1.6776 O 0 0 0 0 0 0 0 0 0 0 0 0 11.7203 6.3981 -1.7494 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2156 -1.8077 0.2592 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2162 3.0827 -0.5605 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5411 -0.4818 1.1560 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6626 1.9432 0.7825 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2542 -2.6726 -0.9092 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6946 -2.3881 0.7918 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9664 -2.6636 -0.4227 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2550 3.5205 -1.9483 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9696 3.6670 -1.4933 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7038 3.8047 -0.2495 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4107 4.9374 1.9897 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7097 4.4182 -1.6729 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5392 3.3181 -1.7902 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9978 6.3832 3.2133 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1627 7.4838 3.3446 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8126 7.2463 1.5434 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9052 7.1234 0.0721 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0399 5.3583 -1.8182 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2764 6.7052 -2.6963 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5816 7.0292 -1.5303 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 30 1 0 0 0 0 4 5 2 0 0 0 0 4 31 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 32 1 0 0 0 0 9 10 2 0 0 0 0 9 33 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 34 1 0 0 0 0 13 35 1 0 0 0 0 13 36 1 0 0 0 0 14 37 1 0 0 0 0 14 38 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 40 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 41 1 0 0 0 0 19 42 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 23 24 2 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 46 1 0 0 0 0 29 47 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 M END > 540646 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 14 > 2008 > 540646 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 14 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 55 60 0 0 0 0 0 0 0 0999 V2000 -1.0574 -0.6776 2.4227 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3265 -0.9547 3.5658 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9042 -1.5745 3.4516 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3939 -1.9059 2.2725 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7355 -1.6630 1.1518 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5178 -1.0385 1.1861 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2769 -2.0208 -0.0380 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5383 -2.5269 -0.0387 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5897 -1.7442 -0.4230 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8900 -2.2406 -0.4256 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1513 -3.5374 -0.0403 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7653 -3.8590 0.3628 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0861 -4.3712 0.3623 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3110 -5.6975 0.7623 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2594 -6.4737 1.1450 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9604 -5.9707 1.1452 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7056 -4.6886 0.7637 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2576 -0.7642 -0.0678 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5084 -0.1408 -0.0321 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1589 0.1000 -1.2287 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5829 -0.2639 -2.3638 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.3959 -0.8535 -2.3684 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7389 -1.1026 -1.2468 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4612 -4.0236 -0.0484 N 0 0 0 0 0 0 0 0 0 0 0 0 7.5134 -3.1685 -0.3092 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1921 -3.6637 -0.4748 S 0 0 0 0 0 0 0 0 0 0 0 0 7.4035 -1.8943 -0.4714 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5263 -1.1915 -0.7206 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6707 -1.9932 -0.7661 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9184 -1.4270 -1.0151 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0358 -0.0693 -1.2144 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9089 0.7382 -1.1673 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6705 0.1961 -0.9329 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8289 -1.2184 -3.5772 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.5402 -0.9519 -4.8299 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0231 -0.1982 2.4863 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7142 -0.6887 4.5381 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4743 -1.7907 4.3430 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4093 -0.7245 -0.7298 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7042 -1.6015 -0.7339 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3129 -6.1006 0.7663 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4351 -7.4940 1.4524 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1435 -6.6066 1.4530 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6935 -4.3117 0.7691 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9564 0.1457 0.9079 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1266 0.5794 -1.2370 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6314 -4.9619 0.1292 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7967 -2.0544 -1.0517 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0050 0.3665 -1.4069 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0062 1.8024 -1.3238 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8020 0.8371 -0.8990 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0393 -1.6506 -3.5948 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4985 -1.4710 -4.8212 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7086 0.1202 -4.9311 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9425 -1.3066 -5.6696 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 36 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 48 1 0 0 0 0 31 32 1 0 0 0 0 31 49 1 0 0 0 0 32 33 2 0 0 0 0 32 50 1 0 0 0 0 33 51 1 0 0 0 0 34 35 1 0 0 0 0 34 52 1 0 0 0 0 35 53 1 0 0 0 0 35 54 1 0 0 0 0 35 55 1 0 0 0 0 M END > 596071 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 9 > 2010 > 596071 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19062275 > Bioorg. Med. Chem. Lett.|2009|19|2|424 > 14 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 55 60 0 0 0 0 0 0 0 0999 V2000 -0.0668 0.7021 2.9232 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9452 0.7388 3.8678 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0960 0.0014 3.6594 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2466 -0.7360 2.5761 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3104 -0.8047 1.6448 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1160 -0.0864 1.7849 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5076 -1.5753 0.5476 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7120 -2.1892 0.4072 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7251 -1.5641 -0.2628 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9678 -2.1724 -0.4136 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2093 -3.4238 0.1100 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9206 -3.4701 0.9576 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1829 -4.0954 0.8081 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3893 -5.3710 1.3558 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3761 -5.9901 2.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1348 -5.3755 2.1705 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8994 -4.1385 1.6521 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9344 -0.1605 0.7429 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1260 0.5570 0.8839 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0752 0.4612 -0.1176 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8298 -0.3008 -1.1719 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.6910 -0.9704 -1.2798 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7560 -0.9072 -0.3453 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4614 -4.0238 -0.0493 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4088 -3.4360 -0.8581 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6684 -3.8795 -1.0173 O 0 0 0 0 0 0 0 0 0 0 0 0 7.2131 -2.3677 -1.5883 N 0 0 0 0 0 0 0 0 0 0 0 0 8.3646 -2.0761 -2.2525 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3008 -3.0530 -1.8819 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5814 -3.0153 -2.4090 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0099 -1.0486 -3.6633 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7313 -1.0730 -3.1510 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4742 -1.7559 -2.3986 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4967 -1.8393 -3.4445 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9323 -2.0154 -3.2935 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9770 1.2658 3.0653 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8365 1.3384 4.7594 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8853 0.0299 4.3960 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5591 -0.5828 -0.6823 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7523 -1.6574 -0.9480 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3466 -5.8593 1.2485 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5372 -6.9718 2.4431 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3476 -5.8873 2.7042 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9321 -3.6739 1.7742 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3014 1.1714 1.7546 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0067 1.0021 -0.0401 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6632 -4.8541 0.4097 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3043 -3.7670 -2.1281 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2957 -0.2712 -4.3564 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0160 -0.3179 -3.4421 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6452 -2.2512 -2.4902 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4193 -2.2349 -3.0198 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6812 -0.8455 -3.8522 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1502 -2.4997 -4.2395 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9312 -1.9880 -3.7032 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 36 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 33 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 32 1 0 0 0 0 29 30 1 0 0 0 0 30 35 2 0 0 0 0 30 48 1 0 0 0 0 31 35 1 0 0 0 0 31 32 2 0 0 0 0 31 49 1 0 0 0 0 32 50 1 0 0 0 0 33 34 1 0 0 0 0 33 51 1 0 0 0 0 34 52 1 0 0 0 0 34 53 1 0 0 0 0 34 54 1 0 0 0 0 35 55 1 0 0 0 0 M END > 596070 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 8 > 2010 > 596070 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19062275 > Bioorg. Med. Chem. Lett.|2009|19|2|424 > 13 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 61 65 0 0 0 0 0 0 0 0999 V2000 -0.0180 1.4768 0.0102 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1425 2.2531 0.0310 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6717 3.6895 0.0316 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7949 3.6336 0.0095 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1623 2.3400 0.0035 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5272 1.7866 0.0487 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1994 1.2559 1.1154 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4675 0.9455 0.7473 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4791 1.8006 -1.0787 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6755 1.2622 -0.5797 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7754 1.1457 -1.4238 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6821 1.5574 -2.7353 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4986 2.0890 -3.2268 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4001 2.2170 -2.4050 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4930 -0.7152 1.0950 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4785 -2.0993 1.0829 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0292 -2.7809 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5238 -2.0737 -1.1088 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5108 -0.6896 -1.1010 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0201 -2.7425 -2.1838 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5116 -1.9530 -3.2688 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0425 -4.1417 -0.0279 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.1091 -4.7979 -0.5620 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9607 -2.7932 2.1485 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.4665 -2.0292 3.2451 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3132 1.9441 -0.0133 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.4745 0.3570 1.6337 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9117 0.1657 2.9332 O 0 0 0 0 0 0 0 0 0 0 0 0 -5.7202 -0.3756 3.8821 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2388 -0.5891 5.1656 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0626 -1.1395 6.1283 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3659 -1.4775 5.8136 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.8479 -1.2661 4.5350 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.0299 -0.7103 3.5704 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0414 4.2018 -0.8567 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0145 4.2012 0.9309 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3942 4.3962 0.0046 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7835 1.1064 2.1008 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.7012 0.7327 -1.0514 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5384 1.4652 -3.3870 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4393 2.4074 -4.2571 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4798 2.6310 -2.7898 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8870 -0.1864 1.9502 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8953 -0.1408 -1.9480 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3253 -1.3188 -2.9172 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8774 -2.6088 -4.0589 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7068 -1.3292 -3.6579 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2486 -4.4988 -1.6009 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9687 -5.8776 -0.5104 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9885 -4.5178 0.0179 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2928 -1.4060 2.9032 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8187 -2.7034 4.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6738 -1.3955 3.6427 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.3321 1.0260 1.7041 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7953 -0.6040 1.2316 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2208 -0.3256 5.4118 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6883 -1.3062 7.1275 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.0083 -1.9077 6.5676 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.8660 -1.5316 4.2914 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.4069 -0.5454 2.5718 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 2 6 1 0 0 0 0 2 3 1 0 0 0 0 3 4 1 0 0 0 0 3 36 1 0 0 0 0 3 37 1 0 0 0 0 4 5 1 0 0 0 0 4 38 1 0 0 0 0 5 27 2 0 0 0 0 6 9 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 39 1 0 0 0 0 8 28 1 0 0 0 0 8 10 1 0 0 0 0 9 10 2 0 0 0 0 9 14 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 40 1 0 0 0 0 12 13 1 0 0 0 0 12 41 1 0 0 0 0 13 14 2 0 0 0 0 13 42 1 0 0 0 0 14 43 1 0 0 0 0 15 20 1 0 0 0 0 15 16 2 0 0 0 0 16 17 1 0 0 0 0 16 44 1 0 0 0 0 17 18 2 0 0 0 0 17 25 1 0 0 0 0 18 19 1 0 0 0 0 18 23 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 20 45 1 0 0 0 0 21 22 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 22 48 1 0 0 0 0 23 24 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 25 26 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 26 54 1 0 0 0 0 28 29 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 35 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 32 33 2 0 0 0 0 32 58 1 0 0 0 0 33 34 1 0 0 0 0 33 59 1 0 0 0 0 34 35 2 0 0 0 0 34 60 1 0 0 0 0 35 61 1 0 0 0 0 M END > 549201 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 25 > 2008 > 549201 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 25 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 31 34 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8410 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3464 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6789 -1.7489 -0.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 -2.7027 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0037 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -0.9593 0.0063 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1704 -0.0392 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6159 -3.2264 0.6732 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0785 -1.5802 -0.7635 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0263 O 0 0 0 0 0 0 0 0 0 0 0 0 5.3095 -2.3173 -0.4875 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9643 -3.3385 0.4187 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9497 -4.2123 0.8674 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2457 -4.0698 0.4228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5819 -3.0610 -0.4705 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6317 -2.1920 -0.9255 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0007 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9090 -3.7540 -0.0256 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4432 -3.0501 -0.0002 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0253 -0.6586 0.0182 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1101 -3.8042 1.2658 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9723 -0.7286 -1.4192 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6993 -4.9999 1.5627 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0085 -4.7495 0.7728 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6030 -2.9631 -0.8083 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9006 -1.4100 -1.6200 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 20 1 0 0 0 0 1 21 1 0 0 0 0 2 3 1 0 0 0 0 2 22 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 23 1 0 0 0 0 8 9 2 0 0 0 0 8 24 1 0 0 0 0 9 25 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 26 1 0 0 0 0 12 14 1 0 0 0 0 12 27 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 28 1 0 0 0 0 17 18 1 0 0 0 0 17 29 1 0 0 0 0 18 19 2 0 0 0 0 18 30 1 0 0 0 0 19 31 1 0 0 0 0 M END > 592715 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12i > 2008 > 592715 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12i > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 67 70 0 0 0 0 0 0 0 0999 V2000 3.8293 1.4867 -1.6991 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9197 2.3075 -1.3995 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2017 1.7993 -1.3853 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0065 0.1664 -1.9842 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2960 -0.3779 -1.9776 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4085 0.4461 -1.6748 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6346 -0.1000 -1.6746 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7958 -1.3725 -1.9499 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7877 -2.1799 -2.2381 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5352 -1.7429 -2.2661 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4940 -2.5959 -2.5677 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7519 -3.9433 -2.8498 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0152 -4.5566 -2.8611 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8408 -5.8598 -3.1773 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5199 -6.0685 -3.3600 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8548 -4.8547 -3.1442 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9284 -6.8953 -3.3039 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2364 -7.4692 -1.9449 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1832 -8.4192 -1.8134 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5378 -8.8823 -0.5415 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5720 -9.0029 0.4490 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9238 -9.4607 1.7040 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2361 -9.7990 1.9757 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2029 -9.6798 0.9906 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8549 -9.2274 -0.2693 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4849 -10.0108 1.2590 F 0 0 0 0 0 0 0 0 0 0 0 0 4.7148 3.6203 -1.1195 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3646 4.0872 -1.1501 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3329 5.5789 -0.8114 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8872 6.0787 -0.8442 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8568 7.5110 -0.5191 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5258 8.0796 -0.7699 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6183 9.6067 -0.7857 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4427 10.0228 -1.8762 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2760 7.7446 0.8693 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2936 7.0588 1.8209 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6321 -7.0761 -0.9695 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8328 1.9034 -1.7005 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0390 2.4406 -1.1530 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1557 -0.4578 -2.2140 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7962 -1.7793 -1.9412 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5832 -2.2627 -2.5845 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9586 -4.0731 -2.6546 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1036 -6.9123 -3.5957 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5953 -7.6928 -3.9681 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8255 -6.4316 -3.7143 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6189 -8.7820 -2.6005 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5463 -8.7386 0.2383 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1724 -9.5540 2.4741 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5084 -10.1566 2.9577 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6081 -9.1346 -1.0377 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9489 3.9317 -2.1456 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7729 3.5360 -0.4191 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7486 5.7344 0.1841 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9246 6.1300 -1.5424 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4715 5.9232 -1.8398 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2956 5.5276 -0.1133 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1561 7.7281 -1.7332 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1581 7.7651 0.0184 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3794 10.0300 -0.9023 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0530 9.9540 0.1516 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5460 10.9816 -1.9476 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2747 7.3352 1.0211 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2881 8.8160 1.0698 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2965 7.4742 1.6750 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2752 5.9887 1.6148 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6094 7.2251 2.8509 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 38 1 0 0 0 0 2 3 1 0 0 0 0 2 27 1 0 0 0 0 3 6 2 0 0 0 0 3 39 1 0 0 0 0 4 5 2 0 0 0 0 4 40 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 41 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 42 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 13 14 2 0 0 0 0 13 43 1 0 0 0 0 14 15 1 0 0 0 0 14 17 1 0 0 0 0 15 16 1 0 0 0 0 15 44 1 0 0 0 0 17 18 1 0 0 0 0 17 45 1 0 0 0 0 17 46 1 0 0 0 0 18 19 1 0 0 0 0 18 37 2 0 0 0 0 19 20 1 0 0 0 0 19 47 1 0 0 0 0 20 21 2 0 0 0 0 20 25 1 0 0 0 0 21 22 1 0 0 0 0 21 48 1 0 0 0 0 22 23 2 0 0 0 0 22 49 1 0 0 0 0 23 24 1 0 0 0 0 23 50 1 0 0 0 0 24 25 2 0 0 0 0 24 26 1 0 0 0 0 25 51 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 35 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 65 1 0 0 0 0 36 66 1 0 0 0 0 36 67 1 0 0 0 0 M END > 463083 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17373783 > J. Med. Chem.|2007|50|9|2213 > 34 > 2007 > 463083 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17373783 > J. Med. Chem.|2007|50|9|2213 > 34 > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 69 73 0 0 0 0 0 0 0 0999 V2000 -0.1328 1.2143 -0.1669 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3190 -0.0954 -0.5239 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7686 -0.9101 -0.7097 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0124 -0.4352 -0.5452 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2196 0.8175 -0.2033 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1430 1.6818 -0.0030 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4705 -0.8540 -0.7621 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1104 -2.0839 -1.0813 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2853 -2.1612 -1.0600 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2143 2.0502 0.0190 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.2003 1.7201 0.9528 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9929 0.3105 2.7263 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0181 0.6366 1.8033 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3607 2.4779 1.0359 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3357 2.1476 1.9635 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.1505 1.0608 2.8070 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.4725 2.8876 2.0477 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.0342 -3.1989 -1.4088 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4089 -2.9909 -1.3954 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2704 -4.0426 -1.7039 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7479 -5.2971 -2.0241 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3818 -5.4956 -2.0353 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5244 -4.4549 -1.7358 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7336 -3.8302 -1.6916 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.5649 -4.8482 -1.9901 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.1868 -2.7375 -1.4121 O 0 0 0 0 0 0 0 0 0 0 0 0 -8.0181 -4.6372 -1.9778 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.4593 -4.1060 -3.3430 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.9723 -3.8802 -3.3447 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.6926 -5.0703 -2.9270 N 0 0 0 0 0 0 0 0 0 0 0 0 -10.2348 -5.8023 -1.7606 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.7181 -5.9719 -1.7258 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.3229 -2.6660 -2.4844 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.3891 -3.5550 -4.7962 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.7126 -5.1480 -0.4608 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.8568 -7.2167 -1.8136 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.1393 -4.8538 -2.9049 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2293 1.1792 -0.0758 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3148 2.7104 0.2778 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8793 -3.0366 -1.2777 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2905 2.8670 -0.4985 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8498 -0.5322 3.3864 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1142 0.0488 1.7425 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.5030 3.3233 0.3791 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9107 0.8034 3.5297 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1884 2.5750 1.4778 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.8077 -2.0185 -1.1466 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4135 -6.1134 -2.2631 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9816 -6.4675 -2.2835 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4566 -4.6155 -1.7506 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.2033 -5.7202 -2.2131 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.2643 -3.9258 -1.1944 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.9517 -3.1621 -3.5471 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1990 -4.8293 -4.1168 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.4162 -6.6890 -2.4935 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.4185 -6.3592 -0.7488 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.8286 -1.7813 -2.8859 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.4023 -2.5143 -2.4926 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.9877 -2.8366 -1.4613 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.1272 -4.3905 -5.4453 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.4654 -3.3873 -4.8363 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.8689 -2.6576 -5.1312 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.8022 -5.1234 -0.4455 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.3502 -5.7242 0.3906 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.3253 -4.1308 -0.4023 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.5362 -7.7207 -2.7254 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.5290 -7.7905 -0.9468 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.9438 -7.1361 -1.8060 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.6488 -5.6285 -2.6305 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 10 1 0 0 0 0 2 7 1 0 0 0 0 2 3 1 0 0 0 0 3 4 1 0 0 0 0 3 9 2 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 5 38 1 0 0 0 0 6 39 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 18 1 0 0 0 0 9 40 1 0 0 0 0 10 11 1 0 0 0 0 10 41 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 42 1 0 0 0 0 13 43 1 0 0 0 0 14 15 2 0 0 0 0 14 44 1 0 0 0 0 15 16 1 0 0 0 0 15 17 1 0 0 0 0 16 45 1 0 0 0 0 17 46 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 47 1 0 0 0 0 20 21 2 0 0 0 0 20 24 1 0 0 0 0 21 22 1 0 0 0 0 21 48 1 0 0 0 0 22 23 2 0 0 0 0 22 49 1 0 0 0 0 23 50 1 0 0 0 0 24 25 1 0 0 0 0 24 26 2 0 0 0 0 25 27 1 0 0 0 0 25 51 1 0 0 0 0 27 32 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 28 29 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 29 30 1 0 0 0 0 29 33 1 0 0 0 0 29 34 1 0 0 0 0 30 31 1 0 0 0 0 30 37 1 0 0 0 0 31 32 1 0 0 0 0 31 35 1 0 0 0 0 31 36 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 34 60 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 36 66 1 0 0 0 0 36 67 1 0 0 0 0 36 68 1 0 0 0 0 37 69 1 0 0 0 0 M END > 744547 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 20038108 > J. Med. Chem.|2010|53|3|1238 > 1 > 2010 > 744547 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20038108 > J. Med. Chem.|2010|53|3|1238 > 1 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 74 80 0 0 0 0 0 0 0 0999 V2000 -0.2528 0.9867 1.0408 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9435 1.6803 1.1136 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1340 1.0032 0.9244 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1496 -0.2922 0.6757 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0351 -0.9994 0.5961 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2102 -0.3841 0.7763 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0982 -2.3284 0.3381 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3158 -2.8690 0.0691 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6950 -3.0929 -1.2239 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9392 -3.6407 -1.5219 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8231 -3.9724 -0.5184 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1928 -3.1947 1.1237 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4608 -3.7527 0.8279 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3328 -4.0777 1.8785 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9503 -3.8526 3.1661 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7038 -3.3034 3.4574 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8345 -2.9719 2.4630 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4606 -1.1737 0.6882 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7032 -0.5573 0.8625 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8434 -1.3341 0.7656 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7260 -2.6283 0.5128 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5348 -3.1868 0.3520 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4186 -2.4808 0.4364 N 0 0 0 0 0 0 0 0 0 0 0 0 6.0690 -4.5226 -0.8312 N 0 0 0 0 0 0 0 0 0 0 0 0 6.3524 -4.8951 -2.1292 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4945 -5.5260 -2.5330 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5638 -4.7015 -3.1570 N 0 0 0 0 0 0 0 0 0 0 0 0 6.1511 -5.1889 -4.2810 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3932 -5.7230 -3.9003 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2206 -6.2985 -4.8526 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8222 -6.3413 -6.1728 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5983 -5.8122 -6.5549 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7604 -5.2444 -5.6214 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4563 -4.5435 0.0890 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.6801 -5.3428 -0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3159 -6.7993 -0.3034 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5943 -7.6089 -0.5293 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2522 -9.0037 -0.8633 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8175 -9.8891 0.1770 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9959 -9.0861 0.7822 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.4312 -7.6412 0.7668 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7974 -9.1780 -0.9692 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1955 1.4924 1.1893 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9466 2.7412 1.3162 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0671 1.5441 0.9808 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0187 -2.8412 -2.0275 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2152 -3.8082 -2.5526 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3022 -4.5044 1.6669 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6230 -4.1038 3.9728 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4239 -3.1350 4.4868 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8713 -2.5468 2.7036 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7712 0.5008 1.0682 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.8192 -0.8898 0.8952 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7346 -4.6427 -0.1359 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2382 -5.7872 -1.9677 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1750 -6.7120 -4.5617 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4677 -6.7895 -6.9137 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2976 -5.8513 -7.5914 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8089 -4.8343 -5.9258 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5909 -4.9650 -0.0309 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2255 -5.2884 0.9338 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3048 -4.9544 -0.8127 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6944 -6.8444 -1.1977 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7672 -7.2149 0.5417 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1756 -7.1659 -1.3380 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1791 -10.8157 -0.2688 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0704 -10.1012 0.9418 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.8845 -9.1648 0.1559 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.2079 -9.4116 1.8007 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7999 -7.4649 1.6377 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.2400 -6.9119 0.7216 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3358 -8.9744 -0.0030 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5751 -10.2020 -1.2695 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4019 -8.4871 -1.7137 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 43 1 0 0 0 0 2 3 1 0 0 0 0 2 44 1 0 0 0 0 3 4 2 0 0 0 0 3 45 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 12 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 46 1 0 0 0 0 10 11 2 0 0 0 0 10 47 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 13 1 0 0 0 0 12 17 2 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 48 1 0 0 0 0 15 16 2 0 0 0 0 15 49 1 0 0 0 0 16 17 1 0 0 0 0 16 50 1 0 0 0 0 17 51 1 0 0 0 0 18 23 1 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 19 52 1 0 0 0 0 20 21 2 0 0 0 0 20 53 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 54 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 26 55 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 32 33 2 0 0 0 0 32 58 1 0 0 0 0 33 59 1 0 0 0 0 34 35 1 0 0 0 0 34 60 1 0 0 0 0 35 36 1 0 0 0 0 35 61 1 0 0 0 0 35 62 1 0 0 0 0 36 37 1 0 0 0 0 36 63 1 0 0 0 0 36 64 1 0 0 0 0 37 38 1 0 0 0 0 37 41 1 0 0 0 0 37 65 1 0 0 0 0 38 39 1 0 0 0 0 38 42 1 0 0 0 0 39 40 1 0 0 0 0 39 66 1 0 0 0 0 39 67 1 0 0 0 0 40 41 1 0 0 0 0 40 68 1 0 0 0 0 40 69 1 0 0 0 0 41 70 1 0 0 0 0 41 71 1 0 0 0 0 42 72 1 0 0 0 0 42 73 1 0 0 0 0 42 74 1 0 0 0 0 M END > 731887 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 2 > 2010 > 731887 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 2 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 59 62 0 0 0 0 0 0 0 0999 V2000 -1.1968 -0.9978 2.4052 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5343 -1.4331 3.5407 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7028 -2.0377 3.4157 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2628 -2.2066 2.2334 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6715 -1.8088 1.1196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5835 -1.1884 1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2838 -2.0027 -0.0739 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5433 -2.5131 -0.0693 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6186 -1.6843 -0.2198 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9167 -2.1863 -0.2180 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1519 -3.5346 -0.0637 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7436 -3.8986 0.0966 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0621 -4.4169 0.0945 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2603 -5.7971 0.2550 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1852 -6.6194 0.4055 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8883 -6.1108 0.4027 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6595 -4.7762 0.2589 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2481 -0.7407 -0.0811 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5007 -0.1216 -0.0344 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0796 0.2845 -1.2231 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4361 0.0768 -2.3612 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2491 -0.5127 -2.3762 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6592 -0.9168 -1.2625 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4617 -4.0259 -0.0642 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4840 -3.2197 0.2844 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6100 -0.7109 -3.5879 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2460 -0.2708 -4.8321 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7542 -3.6566 0.1751 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2602 -2.0982 0.6974 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8654 -2.7803 0.5540 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7322 -2.3965 2.0290 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1905 -3.5134 0.3355 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8341 -1.5159 -0.3069 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1659 -0.5266 2.4766 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9799 -1.3010 4.5156 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2196 -2.3772 4.3012 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4590 -0.6232 -0.3424 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7501 -1.5101 -0.3395 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2603 -6.2050 0.2587 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3399 -7.6820 0.5208 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0525 -6.7840 0.5235 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6487 -4.3958 0.2589 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0047 0.0356 0.9078 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0466 0.7656 -1.2228 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6342 -4.9468 -0.3154 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2590 -1.1411 -3.6132 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5983 -0.5098 -5.6755 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2017 -0.7812 -4.9519 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4114 0.8059 -4.7946 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9327 -4.5513 -0.1544 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7544 -3.2973 2.6423 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5589 -1.7444 2.3109 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7882 -1.8742 2.1847 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2854 -3.7869 -0.7154 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0172 -2.8614 0.6174 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2127 -4.4142 0.9488 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8902 -0.9936 -0.1512 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6609 -0.8639 -0.0250 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9291 -1.7894 -1.3578 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 34 1 0 0 0 0 2 3 1 0 0 0 0 2 35 1 0 0 0 0 3 4 2 0 0 0 0 3 36 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 37 1 0 0 0 0 10 11 2 0 0 0 0 10 38 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 39 1 0 0 0 0 15 16 2 0 0 0 0 15 40 1 0 0 0 0 16 17 1 0 0 0 0 16 41 1 0 0 0 0 17 42 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 43 1 0 0 0 0 20 21 2 0 0 0 0 20 44 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 26 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 25 28 1 0 0 0 0 25 29 2 0 0 0 0 26 27 1 0 0 0 0 26 46 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 30 1 0 0 0 0 28 50 1 0 0 0 0 30 31 1 0 0 0 0 30 32 1 0 0 0 0 30 33 1 0 0 0 0 31 51 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > 732021 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 11 > 2010 > 732021 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 11 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 42 45 0 0 0 999 V2000 2.0685 1.0373 -1.6762 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9657 -0.3094 -1.4973 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0326 -0.8735 -0.2292 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2064 -0.0755 0.8916 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2460 1.8852 -0.5683 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3165 1.3292 0.7323 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4929 2.1719 1.8380 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5953 3.5174 1.6566 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5270 4.0760 0.3772 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3548 3.2762 -0.7298 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2754 -0.6812 2.2344 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0788 -2.0058 2.3872 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5098 0.0145 3.2038 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6317 5.4221 0.2246 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8592 5.9834 0.3510 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3760 7.1072 0.6104 N 0 0 0 0 0 0 0 0 0 0 0 0 6.2325 5.8029 0.6445 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9881 5.1998 0.5182 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3292 7.9242 0.4465 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0263 7.3858 0.3103 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9301 8.2444 0.1379 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1235 9.5906 0.1025 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4054 10.1330 0.2360 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5008 9.3175 0.4059 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5714 11.4806 0.1972 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3966 12.2741 0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0180 1.4541 -2.6713 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8296 -0.9498 -2.3562 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9479 -1.9441 -0.1152 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5471 1.7547 2.8327 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7307 4.1617 2.5128 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3037 3.7151 -1.7153 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1242 -2.4041 3.2704 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8918 -2.5607 1.6138 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1058 5.1818 0.7784 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9013 4.1238 0.5506 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9352 7.8375 0.0333 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2771 10.2480 -0.0307 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4866 9.7465 0.5081 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9205 12.0104 -0.9263 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7038 12.0879 0.8387 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6694 13.3294 0.0052 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 27 1 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 4 2 0 0 0 0 3 29 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 6 1 0 0 0 0 5 10 2 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 30 1 0 0 0 0 8 9 2 0 0 0 0 8 31 1 0 0 0 0 9 14 1 0 0 0 0 9 10 1 0 0 0 0 10 32 1 0 0 0 0 11 13 2 0 0 0 0 11 12 1 0 0 0 0 12 33 1 0 0 0 0 12 34 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 35 1 0 0 0 0 18 36 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 37 1 0 0 0 0 22 23 1 0 0 0 0 22 38 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 24 39 1 0 0 0 0 25 26 1 0 0 0 0 26 40 1 0 0 0 0 26 41 1 0 0 0 0 26 42 1 0 0 0 0 M END > 541097 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 28 > 2008 > 541097 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 28 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 53 57 0 0 0 0 0 0 0 0999 V2000 -0.4168 1.3450 0.1730 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5666 1.9741 1.4172 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6000 1.2454 2.5711 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3011 -0.0124 0.0889 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3268 -0.7853 1.2594 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4835 -0.1534 2.5171 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5083 -0.8885 3.6352 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3902 -2.1951 3.6026 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2332 -2.8868 2.4081 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2103 -2.1927 1.2112 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0692 -2.8422 0.0293 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.0622 -4.2008 0.0449 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1173 -4.8712 -0.1167 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2842 -6.2563 0.2518 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2610 -4.8953 0.2317 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0925 -6.9753 0.0832 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1254 -6.2760 -0.1007 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3209 -6.9975 -0.2644 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3055 -8.3601 -0.2460 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1210 -9.0634 -0.0673 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0819 -8.3926 0.0976 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3348 -9.1455 0.2925 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3303 -10.4914 0.2210 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.3720 -8.5521 0.5177 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5749 -11.2394 0.4146 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3920 2.0943 -0.9614 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.2428 1.3942 -2.1982 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6797 3.3270 1.4751 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.8296 3.9106 2.7709 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6724 -12.6262 -0.2243 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5174 -12.4916 1.2919 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7152 1.7430 3.5227 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1822 -0.4884 -0.8733 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4155 -2.7479 4.5300 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1382 -3.9626 2.4130 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0381 -4.3244 -0.2562 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2179 -6.7804 0.3930 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1810 -4.3447 0.3621 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2532 -6.4709 -0.4055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2306 -8.9028 -0.3729 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1368 -10.1432 -0.0571 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5029 -10.9647 0.0413 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4834 -10.6384 0.4537 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2385 2.1083 -3.0217 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6966 0.8414 -2.1917 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0727 0.6989 -2.3245 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0372 3.6627 3.3835 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9087 4.9935 2.6747 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7315 3.5209 3.2428 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6450 -12.9377 -0.6051 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8104 -12.9820 -0.7886 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5535 -12.7588 1.7250 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3882 -12.7145 1.9085 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 26 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 6 2 0 0 0 0 3 32 1 0 0 0 0 4 5 2 0 0 0 0 4 33 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 34 1 0 0 0 0 9 10 2 0 0 0 0 9 35 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 15 1 0 0 0 0 13 17 1 0 0 0 0 13 36 1 0 0 0 0 14 16 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 16 21 2 0 0 0 0 17 18 2 0 0 0 0 18 19 1 0 0 0 0 18 39 1 0 0 0 0 19 20 2 0 0 0 0 19 40 1 0 0 0 0 20 21 1 0 0 0 0 20 41 1 0 0 0 0 21 22 1 0 0 0 0 22 23 1 0 0 0 0 22 24 2 0 0 0 0 23 25 1 0 0 0 0 23 42 1 0 0 0 0 25 30 1 0 0 0 0 25 31 1 0 0 0 0 25 43 1 0 0 0 0 26 27 1 0 0 0 0 27 44 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 28 29 1 0 0 0 0 29 47 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 30 31 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 M END > 540615 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 3 > 2008 > 540615 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324761 > J. Med. Chem.|2008|51|6|1649 > 72 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 43 46 0 0 0 0 0 0 0 0999 V2000 -1.3449 0.6791 1.0049 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1765 -0.6181 0.9574 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0057 -1.1755 0.7628 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0910 -0.4279 0.6046 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3005 1.5261 0.8547 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9638 0.9703 0.6473 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1501 2.2565 0.4830 S 0 0 0 0 0 0 0 0 0 0 0 0 0.9144 3.4852 0.6972 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2739 2.9295 0.8741 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3284 -1.0168 0.4013 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4470 -2.4764 0.3595 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9086 -2.8627 0.1243 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0307 -4.3642 0.0813 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3346 -5.4175 1.4603 S 0 0 0 0 0 0 0 0 0 0 0 0 4.2856 -6.7871 0.4382 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0627 -6.4221 -0.7855 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9217 -5.1283 -1.0069 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4603 -8.1005 0.8580 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4017 -9.1072 -0.0361 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5710 -10.3808 0.3710 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1961 -8.8665 -1.2100 O 0 0 0 0 0 0 0 0 0 0 0 0 4.4138 -11.4328 -0.5383 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8098 -11.2751 -1.8598 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6540 -12.3152 -2.7554 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1039 -13.5127 -2.3378 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7080 -13.6737 -1.0212 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8667 -12.6385 -0.1194 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0176 -15.1791 -0.5009 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -2.0375 -1.2580 1.0825 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0988 4.5493 0.6867 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1666 3.5186 1.0235 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1163 -0.4627 0.2867 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1083 -2.8957 1.3069 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8328 -2.8677 -0.4514 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2474 -2.4434 -0.8231 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5229 -2.4714 0.9352 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7333 -4.7213 -1.9894 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6243 -8.2926 1.7946 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8019 -10.5682 1.2943 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2391 -10.3397 -2.1873 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9620 -12.1925 -3.7833 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9826 -14.3241 -3.0402 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5581 -12.7642 0.9079 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 4 10 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 30 1 0 0 0 0 9 31 1 0 0 0 0 10 11 1 0 0 0 0 10 32 1 0 0 0 0 11 12 1 0 0 0 0 11 33 1 0 0 0 0 11 34 1 0 0 0 0 12 13 1 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 13 14 1 0 0 0 0 13 17 2 0 0 0 0 14 15 1 0 0 0 0 15 16 2 0 0 0 0 15 18 1 0 0 0 0 16 17 1 0 0 0 0 17 37 1 0 0 0 0 18 19 1 0 0 0 0 18 38 1 0 0 0 0 19 20 1 0 0 0 0 19 21 2 0 0 0 0 20 22 1 0 0 0 0 20 39 1 0 0 0 0 22 23 2 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 24 25 2 0 0 0 0 24 41 1 0 0 0 0 25 26 1 0 0 0 0 25 42 1 0 0 0 0 26 27 2 0 0 0 0 26 28 1 0 0 0 0 27 43 1 0 0 0 0 M END > 557531 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 18678489 > Bioorg. Med. Chem. Lett.|2008|18|17|4880 > "21, SNS-314" > 2008 > 557531 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 18678489 > Bioorg. Med. Chem. Lett.|2008|18|17|4880 > "21, SNS-314" > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 50 55 0 0 0 0 0 0 0 0999 V2000 -0.0168 1.3856 0.0097 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1326 2.0398 0.0022 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2941 1.3971 -0.0123 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3650 0.0769 -0.0206 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2519 -0.6538 -0.0139 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9585 -2.0904 -0.0184 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3937 -2.2148 -0.0055 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9706 -0.9803 0.0065 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4690 2.1330 -0.0196 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4136 -0.7279 0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9084 -0.5082 -1.4091 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3553 -0.2551 -1.3935 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1601 -8.8512 5.8738 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2537 -9.9746 5.0639 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4142 -9.8367 3.7048 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2271 -7.6024 5.3365 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3925 -7.4300 3.9440 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4853 -8.5643 3.1303 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6850 -8.0803 1.4511 S 0 0 0 0 0 0 0 0 0 0 0 0 2.6412 -6.3773 1.8641 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4867 -6.2025 3.1766 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7601 -5.2779 0.8843 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8410 -4.2377 0.8895 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9483 -3.1953 -0.0347 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9749 -3.1878 -0.9678 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8083 -5.2780 -0.0524 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9086 -4.2295 -0.9844 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0787 -4.5231 -1.8074 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5921 -5.6422 -1.3825 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8483 -6.1320 -0.3041 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.9540 1.9221 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9312 -3.1516 -0.0047 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4342 3.1024 -0.0141 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3259 1.6786 -0.0302 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9278 -1.5851 0.4566 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6207 0.1606 0.6184 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3942 0.3490 -1.8437 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7013 -1.3968 -2.0055 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5794 0.5255 -0.7948 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7065 -0.1067 -2.3277 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0297 -8.9690 6.9394 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1995 -10.9602 5.5022 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4859 -10.7144 3.0795 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1537 -6.7375 5.9790 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4354 -5.2247 3.6323 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0382 -4.2343 1.6119 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0528 -2.3798 -1.6801 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4513 -3.9205 -2.6225 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0344 -6.9505 0.1821 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 1 32 1 0 0 0 0 2 3 1 0 0 0 0 3 10 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 25 1 0 0 0 0 8 9 1 0 0 0 0 8 33 1 0 0 0 0 9 11 1 0 0 0 0 10 34 1 0 0 0 0 10 35 1 0 0 0 0 11 12 1 0 0 0 0 11 36 1 0 0 0 0 11 37 1 0 0 0 0 12 13 1 0 0 0 0 12 38 1 0 0 0 0 12 39 1 0 0 0 0 13 40 1 0 0 0 0 13 41 1 0 0 0 0 14 15 2 0 0 0 0 14 17 1 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 15 43 1 0 0 0 0 16 19 2 0 0 0 0 16 44 1 0 0 0 0 17 18 2 0 0 0 0 17 45 1 0 0 0 0 18 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 46 1 0 0 0 0 23 27 2 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 26 28 2 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 27 31 1 0 0 0 0 28 29 1 0 0 0 0 29 30 2 0 0 0 0 29 49 1 0 0 0 0 30 31 1 0 0 0 0 31 50 1 0 0 0 0 M END > 690207 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19926477 > Bioorg. Med. Chem. Lett.|2010|20|1|334 > 31a > 2010 > 690207 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 19926477 > Bioorg. Med. Chem. Lett.|2010|20|1|334 > 31a > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 39 42 0 0 0 0 0 0 0 0999 V2000 -0.0164 1.3577 0.0095 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3769 -0.5056 0.0130 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2446 0.5219 0.0271 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.4705 1.7690 0.0322 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2198 -0.8447 -0.0150 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0573 -1.0792 1.0268 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0669 -1.9089 0.6286 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7546 -1.5943 -1.1637 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9124 -2.2413 -0.6997 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6448 -3.0372 -1.5755 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2283 -3.1809 -2.8808 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0837 -2.5390 -3.3327 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3506 -1.7525 -2.4885 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1481 2.2510 0.0032 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3838 3.0910 -1.0926 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4745 3.9309 -1.0906 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3412 3.9463 -0.0039 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1123 3.1149 1.0864 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0248 2.2709 1.0954 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4157 4.7764 -0.0075 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2657 4.7423 1.1407 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6900 -1.6811 0.0095 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.2120 0.4512 0.0361 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6901 2.3433 0.9323 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7019 2.3579 -0.8553 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9429 -0.6716 2.0203 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7883 -2.2186 1.1983 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5370 -3.5404 -1.2331 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7981 -3.7987 -3.5590 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7701 -2.6616 -4.3589 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4607 -1.2562 -2.8464 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7113 3.0795 -1.9376 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6574 4.5787 -1.9351 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7889 3.1311 1.9280 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8477 1.6256 1.9431 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6907 5.0114 2.0266 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6719 3.7381 1.2623 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0831 5.4512 1.0088 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 15 1 0 0 0 0 1 5 1 0 0 0 0 2 3 1 0 0 0 0 2 6 1 0 0 0 0 3 4 1 0 0 0 0 3 23 2 0 0 0 0 4 5 1 0 0 0 0 4 24 1 0 0 0 0 5 25 1 0 0 0 0 5 26 1 0 0 0 0 6 7 2 0 0 0 0 6 9 1 0 0 0 0 7 8 1 0 0 0 0 7 27 1 0 0 0 0 8 10 1 0 0 0 0 8 28 1 0 0 0 0 9 14 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 29 1 0 0 0 0 12 13 1 0 0 0 0 12 30 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 20 1 0 0 0 0 16 17 1 0 0 0 0 16 33 1 0 0 0 0 17 18 2 0 0 0 0 17 34 1 0 0 0 0 18 19 1 0 0 0 0 18 21 1 0 0 0 0 19 20 2 0 0 0 0 19 35 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 M END > 549341 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 33 > 2008 > 549341 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 33 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 38 41 0 0 0 999 V2000 -0.0166 1.3741 0.0096 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2591 1.8054 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1251 0.7083 -0.0144 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4143 -0.4000 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9395 -1.7807 -0.0265 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7086 -3.0555 0.0409 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4659 -3.4743 0.0277 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4192 -2.6664 0.0217 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5736 -1.2838 0.0301 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4085 -0.3879 0.0233 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1650 -0.9015 0.0088 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2576 -2.1342 -0.0409 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2171 -2.8796 -0.0202 N 0 0 0 0 0 0 0 0 0 0 0 0 2.0302 -3.9424 -0.0302 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3048 -3.5030 -0.0484 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5951 -5.3852 -0.0274 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2013 -5.4522 -0.1281 F 0 0 0 0 0 0 0 0 0 0 0 0 2.1737 -6.0488 -1.1146 F 0 0 0 0 0 0 0 0 0 0 0 0 2.0064 -5.9940 1.1632 F 0 0 0 0 0 0 0 0 0 0 0 0 -6.0084 -1.6835 0.0506 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9377 -0.7531 0.0454 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2079 0.6166 0.0553 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.5038 1.0446 0.0699 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.5581 0.1351 0.0750 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3289 -1.2081 0.0648 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8983 1.9977 0.0254 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5348 2.7354 0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5131 -3.7761 0.0406 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4250 -3.0881 0.0103 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5505 0.6828 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0229 -1.9721 0.0020 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0170 -1.5306 -0.0452 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1948 -4.1147 -0.0606 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3984 1.3315 0.0519 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.7146 2.1038 0.0780 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.5745 0.5003 0.0870 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1569 -1.9015 0.0682 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 27 1 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 12 1 0 0 0 0 6 13 1 0 0 0 0 6 14 2 0 0 0 0 7 8 2 0 0 0 0 7 21 1 0 0 0 0 7 29 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 30 1 0 0 0 0 10 22 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 31 1 0 0 0 0 12 32 1 0 0 0 0 13 16 1 0 0 0 0 13 33 1 0 0 0 0 14 15 1 0 0 0 0 15 16 2 0 0 0 0 15 17 1 0 0 0 0 16 34 1 0 0 0 0 17 18 1 0 0 0 0 17 19 1 0 0 0 0 17 20 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 23 35 1 0 0 0 0 24 25 2 0 0 0 0 24 36 1 0 0 0 0 25 26 1 0 0 0 0 25 37 1 0 0 0 0 26 38 1 0 0 0 0 M END > 510951 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 3c > 2007 > 510951 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 3c > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 60 65 0 0 0 0 0 0 0 0999 V2000 -0.0169 1.3939 0.0097 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1744 0.0051 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2228 -0.5904 0.6605 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3758 -1.9760 0.6235 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4726 -2.7541 -0.1020 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5682 -2.1519 -0.7800 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7170 -0.7784 -0.7479 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4914 -2.6189 1.3512 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7182 -3.8886 1.3795 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.6930 -1.7621 2.3070 S 0 0 0 0 0 0 0 0 0 0 0 0 -4.4780 -3.2870 2.7100 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7714 -4.3248 2.0912 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2264 -5.6492 2.2775 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.3248 -5.9022 3.0401 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0199 -4.8672 3.6503 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.5999 -3.5664 3.4886 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2485 1.9455 -0.0022 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3253 1.1759 0.0641 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7754 2.9909 -0.0333 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5504 1.6936 0.0481 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6347 0.8352 0.1203 N 0 0 0 0 0 0 0 0 0 0 0 0 5.9375 1.3497 0.1057 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1275 1.5345 0.1223 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0445 0.6471 0.1623 N 0 0 0 0 0 0 0 0 0 0 0 0 7.6373 2.7891 0.0362 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2875 2.7070 0.0218 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4500 4.0565 -0.0310 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4280 3.3474 -0.0916 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7506 3.8550 -0.1054 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9567 5.2371 -0.1916 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8711 6.0825 -0.2626 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5657 5.5731 -0.2488 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3421 4.2280 -0.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0681 7.4240 -0.3463 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4219 7.8816 -0.3554 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4904 6.4273 -0.3195 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7963 5.8473 -0.3012 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7968 1.9699 0.0373 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9186 0.0167 1.2205 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5877 -3.8275 -0.1326 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2663 -2.7560 -1.3405 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5330 -0.3128 -1.2806 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6985 -6.4676 1.8106 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6599 -6.9204 3.1718 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.8902 -5.0827 4.2525 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1413 -2.7615 3.9634 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4920 -0.1223 0.1811 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0658 1.2901 0.1517 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6007 3.5380 -0.0431 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6610 4.2979 -1.0728 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8889 4.8724 0.4246 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3877 3.9157 0.5065 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9596 5.6378 -0.2021 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6679 3.8457 -0.1550 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4374 8.9692 -0.4255 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9171 7.5696 0.5641 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9438 7.4549 -1.2120 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9328 5.2887 0.6248 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5453 6.6367 -0.3632 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9067 5.1740 -1.1513 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 17 1 0 0 0 0 1 38 1 0 0 0 0 2 3 2 0 0 0 0 2 7 1 0 0 0 0 3 4 1 0 0 0 0 3 39 1 0 0 0 0 4 5 2 0 0 0 0 4 8 1 0 0 0 0 5 6 1 0 0 0 0 5 40 1 0 0 0 0 6 7 2 0 0 0 0 6 41 1 0 0 0 0 7 42 1 0 0 0 0 8 9 2 0 0 0 0 8 10 1 0 0 0 0 9 12 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 13 43 1 0 0 0 0 14 15 1 0 0 0 0 14 44 1 0 0 0 0 15 16 2 0 0 0 0 15 45 1 0 0 0 0 16 46 1 0 0 0 0 17 18 2 0 0 0 0 17 28 1 0 0 0 0 18 20 1 0 0 0 0 19 29 1 0 0 0 0 19 20 2 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 47 1 0 0 0 0 22 26 1 0 0 0 0 22 24 2 0 0 0 0 23 25 1 0 0 0 0 23 24 1 0 0 0 0 23 48 1 0 0 0 0 25 26 2 0 0 0 0 25 27 1 0 0 0 0 26 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 28 29 1 0 0 0 0 28 33 2 0 0 0 0 29 30 2 0 0 0 0 30 31 1 0 0 0 0 30 53 1 0 0 0 0 31 32 2 0 0 0 0 31 34 1 0 0 0 0 32 33 1 0 0 0 0 32 36 1 0 0 0 0 33 54 1 0 0 0 0 34 35 1 0 0 0 0 35 55 1 0 0 0 0 35 56 1 0 0 0 0 35 57 1 0 0 0 0 36 37 1 0 0 0 0 37 58 1 0 0 0 0 37 59 1 0 0 0 0 37 60 1 0 0 0 0 M END > 557831 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "32, Table 5" > 2009 > 557831 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "32, Table 5" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 55 58 0 0 0 999 V2000 0.2184 1.6837 -0.0864 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0266 0.3349 -0.0959 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1009 -0.5448 -0.0419 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4019 -0.0691 0.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5205 2.2111 -0.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6284 1.3305 0.0337 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9263 1.8553 0.0987 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1103 3.2046 0.1078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0202 4.0773 0.0531 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7420 3.5980 -0.0109 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5373 -1.0085 0.0805 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3115 -2.3318 0.1998 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6771 -0.5891 0.0204 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2338 5.4193 0.0641 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8603 5.9716 -1.0005 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1220 7.0323 -3.1763 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9431 5.7410 -3.0293 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3329 5.2142 -1.9795 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6824 7.8893 -2.2429 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0224 7.3712 -1.1002 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5528 8.2457 -0.1111 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7367 9.5908 -0.2594 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3890 10.1049 -1.3895 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8560 9.2734 -2.3687 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2818 10.4412 0.6991 O 0 0 0 0 0 0 0 0 0 0 0 0 4.5585 11.4470 -1.5127 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2302 11.9111 -2.6855 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6253 9.8571 1.8261 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4394 -3.2650 0.2570 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9119 -4.6949 0.3918 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1879 -5.0488 -0.7883 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6499 -6.3724 -0.7652 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6310 2.3492 -0.1334 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9783 -0.0577 -0.1460 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9209 -1.6096 -0.0501 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7775 1.1920 0.1419 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1118 3.6055 0.1584 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9071 4.2817 -0.0528 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4023 -2.6664 0.2477 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3093 5.0784 -3.7995 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0487 7.8588 0.7622 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3567 9.6814 -3.2343 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2988 12.9986 -2.6586 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2326 11.4846 -2.7229 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6715 11.6041 -3.5697 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3114 9.1809 2.3361 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3131 10.6439 2.5127 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7506 9.3009 1.4889 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0284 -3.1796 -0.6562 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0654 -3.0262 1.1168 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7493 -5.3802 0.5236 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2510 -4.7584 1.2563 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9628 -6.4707 0.0753 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1155 -6.5637 -1.6957 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4611 -7.0925 -0.6574 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 33 1 0 0 0 0 2 3 1 0 0 0 0 2 34 1 0 0 0 0 3 4 2 0 0 0 0 3 35 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 36 1 0 0 0 0 8 9 2 0 0 0 0 8 37 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 38 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 29 1 0 0 0 0 12 39 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 40 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 2 0 0 0 0 23 26 1 0 0 0 0 24 42 1 0 0 0 0 25 28 1 0 0 0 0 26 27 1 0 0 0 0 27 43 1 0 0 0 0 27 44 1 0 0 0 0 27 45 1 0 0 0 0 28 46 1 0 0 0 0 28 47 1 0 0 0 0 28 48 1 0 0 0 0 29 30 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 31 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 32 1 0 0 0 0 32 53 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 M END > 541137 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 24 > 2008 > 541137 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 24 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 46 50 0 0 0 0 0 0 0 0999 V2000 0.6431 1.7158 -2.2886 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6564 2.2944 -1.5212 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5295 1.5041 -0.9043 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4419 0.1872 -1.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4914 -0.3887 -1.7356 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5881 0.3383 -2.3765 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7508 3.6724 -1.4049 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6966 4.2392 -0.5413 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5134 3.5392 0.3614 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2854 4.4418 1.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9730 5.6672 0.5368 N 0 0 0 0 0 0 0 0 0 0 0 0 2.9785 5.5167 -0.4381 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3121 4.1339 2.0675 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3675 -0.6081 -0.3586 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2269 -1.9993 -0.3704 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3515 -2.8099 -0.3617 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2059 -4.1967 -0.3735 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9291 -4.7595 -0.3941 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8153 -3.9441 -0.4031 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9592 -2.5698 -0.3851 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4008 -5.0682 -0.3648 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3722 -6.3580 -0.3745 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0625 -4.4940 -0.3475 S 0 0 0 0 0 0 0 0 0 0 0 0 7.6498 -6.1549 -0.3475 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5450 -7.0143 -0.3650 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7798 -8.4073 -0.3722 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0505 -8.8944 -0.3603 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1406 -8.0354 -0.3403 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9437 -6.6731 -0.3372 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0836 2.3312 -2.7980 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1829 -0.1409 -2.9616 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1617 4.2441 -1.9217 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5232 2.4698 0.5125 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3704 6.5053 0.8206 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2803 3.9639 1.5965 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3862 4.9748 2.7571 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0126 3.2403 2.6151 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1132 -0.1999 0.1085 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3372 -2.3687 -0.3461 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8123 -5.8332 -0.4033 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8280 -4.3817 -0.4193 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0842 -1.9368 -0.3923 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9442 -9.0913 -0.3869 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2126 -9.9621 -0.3660 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1435 -8.4360 -0.3303 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7923 -6.0052 -0.3217 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 30 1 0 0 0 0 2 7 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 4 14 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 31 1 0 0 0 0 7 8 1 0 0 0 0 7 32 1 0 0 0 0 8 9 1 0 0 0 0 8 12 2 0 0 0 0 9 10 2 0 0 0 0 9 33 1 0 0 0 0 10 11 1 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 13 35 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 14 15 1 0 0 0 0 14 38 1 0 0 0 0 15 16 2 0 0 0 0 15 20 1 0 0 0 0 16 17 1 0 0 0 0 16 39 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 18 40 1 0 0 0 0 19 20 2 0 0 0 0 19 41 1 0 0 0 0 20 42 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 29 1 0 0 0 0 25 26 1 0 0 0 0 26 27 2 0 0 0 0 26 43 1 0 0 0 0 27 28 1 0 0 0 0 27 44 1 0 0 0 0 28 29 2 0 0 0 0 28 45 1 0 0 0 0 29 46 1 0 0 0 0 M END > 557830 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "31, Table 5" > 2009 > 557830 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "31, Table 5" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 56 60 0 0 0 0 0 0 0 0999 V2000 -0.0828 1.3503 0.1051 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2226 2.0377 -1.0783 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6020 1.3627 -2.2026 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0070 -0.0115 0.1583 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3803 -0.7305 -0.9824 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6894 -0.0391 -2.1792 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0587 -0.7228 -3.2688 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1448 -2.0323 -3.2634 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8574 -2.7806 -2.1288 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4703 -2.1405 -0.9647 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1840 -2.8449 0.1580 O 0 0 0 0 0 0 0 0 0 0 0 0 0.2066 -4.2014 0.0831 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9582 -4.9038 0.2119 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4735 -6.2189 -0.2109 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4207 -4.8608 -0.1306 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2975 -6.9703 -0.0771 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9356 -6.3064 0.1340 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1154 -7.0601 0.2626 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0704 -8.4199 0.1844 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8708 -9.0889 -0.0222 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3177 -8.3855 -0.1543 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5867 -9.1017 -0.3790 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6173 -10.4484 -0.3353 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6058 -8.4773 -0.6039 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8393 -11.1235 -0.4239 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9831 -10.5678 0.1344 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1882 -11.2366 0.0459 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2566 -12.4592 -0.5988 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1185 -13.0150 -1.1564 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9097 -12.3533 -1.0654 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7731 -13.2970 -0.7088 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -0.4527 2.0477 1.2122 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.7451 1.2904 2.3883 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1393 3.3937 -1.1066 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4621 4.0380 -2.3406 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8340 1.9048 -3.1074 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2436 -0.5329 1.0740 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4470 -2.5423 -4.1661 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9368 -3.8573 -2.1549 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8910 -4.3837 0.3729 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4182 -6.7156 -0.3760 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3287 -4.2853 -0.2336 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0592 -6.5605 0.4241 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9837 -8.9875 0.2851 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8631 -10.1673 -0.0802 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7920 -10.9495 -0.2423 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9304 -9.6133 0.6371 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0779 -10.8049 0.4799 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1749 -13.9689 -1.6597 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0217 -12.7876 -1.5004 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1364 0.7206 2.6820 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0261 1.9669 3.1955 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5688 0.6062 2.1844 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4901 3.8019 -2.6156 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2127 3.6867 -3.1212 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3552 5.1166 -2.2261 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 32 1 0 0 0 0 2 3 1 0 0 0 0 2 34 1 0 0 0 0 3 6 2 0 0 0 0 3 36 1 0 0 0 0 4 5 2 0 0 0 0 4 37 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 38 1 0 0 0 0 9 10 2 0 0 0 0 9 39 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 15 1 0 0 0 0 13 17 1 0 0 0 0 13 40 1 0 0 0 0 14 16 1 0 0 0 0 14 15 2 0 0 0 0 14 41 1 0 0 0 0 15 42 1 0 0 0 0 16 21 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 18 19 1 0 0 0 0 18 43 1 0 0 0 0 19 20 2 0 0 0 0 19 44 1 0 0 0 0 20 21 1 0 0 0 0 20 45 1 0 0 0 0 21 22 1 0 0 0 0 22 23 1 0 0 0 0 22 24 2 0 0 0 0 23 25 1 0 0 0 0 23 46 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 27 28 2 0 0 0 0 27 48 1 0 0 0 0 28 29 1 0 0 0 0 28 31 1 0 0 0 0 29 30 2 0 0 0 0 29 49 1 0 0 0 0 30 50 1 0 0 0 0 32 33 1 0 0 0 0 33 51 1 0 0 0 0 33 52 1 0 0 0 0 33 53 1 0 0 0 0 34 35 1 0 0 0 0 35 54 1 0 0 0 0 35 55 1 0 0 0 0 35 56 1 0 0 0 0 M END > 539796 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 2 > 2008 > 539796 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 18324761 > J. Med. Chem.|2008|51|6|1649 > 48 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 53 57 0 0 0 0 0 0 0 0999 V2000 -0.1615 1.0960 2.3994 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1942 1.5786 2.1123 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9955 0.5185 1.9099 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0918 -0.4101 2.3474 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2328 -0.7329 2.0476 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6023 -2.0878 1.9327 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6409 -3.0803 2.1201 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6621 -2.7360 2.4158 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0268 -1.4029 2.5290 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9967 -2.4538 1.6159 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8043 -1.7990 0.7138 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6822 -3.4845 2.1738 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1814 0.5840 1.6494 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0175 -3.4789 1.5806 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0429 -2.4036 0.6723 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2020 -2.1471 -0.0530 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3130 -2.9418 0.1198 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2918 -4.0068 1.0176 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1528 -4.2790 1.7473 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3983 -4.7813 1.1756 O 0 0 0 0 0 0 0 0 0 0 0 0 9.5434 -4.4448 0.3897 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6804 -5.4199 0.7016 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2745 -6.7812 0.3275 N 0 0 0 0 0 0 0 0 0 0 0 0 11.3759 -7.7320 0.5257 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8761 -9.1550 0.2664 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3457 -9.2512 -1.1668 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2327 -8.2177 -1.3612 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7802 -6.8219 -1.0547 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4734 1.4227 3.3915 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8580 1.4651 1.6466 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4669 2.5087 2.0745 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9168 -4.1208 2.0333 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4022 -3.5092 2.5598 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0489 -1.1429 2.7614 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5416 -1.0285 0.1864 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3112 -4.1767 2.9151 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2303 -1.3245 -0.7522 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2097 -2.7377 -0.4465 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1378 -5.1050 2.4429 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2895 -4.5091 -0.6683 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8606 -3.4291 0.6262 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5676 -5.1367 0.1351 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9046 -5.3876 1.7678 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1853 -7.4996 -0.1664 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7411 -7.6563 1.5499 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6977 -9.8590 0.3984 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0760 -9.3931 0.9673 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1551 -9.0513 -1.8689 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9489 -10.2512 -1.3420 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8802 -8.2521 -2.3920 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4067 -8.4410 -0.6859 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9864 -6.0852 -1.1783 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5970 -6.5937 -1.7394 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 29 1 0 0 0 0 1 30 1 0 0 0 0 2 3 1 0 0 0 0 2 31 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 6 10 1 0 0 0 0 7 8 1 0 0 0 0 7 32 1 0 0 0 0 8 9 2 0 0 0 0 8 33 1 0 0 0 0 9 34 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 35 1 0 0 0 0 12 14 1 0 0 0 0 12 36 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 37 1 0 0 0 0 17 18 1 0 0 0 0 17 38 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 39 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 22 42 1 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 26 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 27 28 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 M END > 592661 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12d > 2008 > 592661 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12d > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 0.0861 1.3579 0.1014 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0715 2.0777 0.4282 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2505 1.4236 0.7097 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0695 -0.0073 0.0550 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1148 -0.6963 0.3421 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2903 0.0247 0.6681 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4152 -0.6598 0.9287 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4220 -1.9707 0.8816 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3492 -2.6857 0.5820 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1862 -2.1093 0.3077 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0299 3.4350 0.4683 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2419 4.1114 0.8082 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2369 2.0262 -0.1782 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3811 1.2371 -0.5101 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0755 -2.8676 -0.0036 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1308 -4.2594 0.0934 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1107 -4.8620 0.8735 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1715 -6.2356 0.9673 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2481 -7.0234 0.2775 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7360 -6.4166 -0.5066 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7925 -5.0417 -0.5966 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3121 -8.4962 0.3760 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1798 -9.1517 1.0715 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7781 -9.6058 -0.4435 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.0721 -10.9799 0.2585 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1136 -10.4942 1.0575 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9362 -11.4278 1.7261 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7160 -12.7642 1.5923 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6810 -13.2376 0.7981 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1371 -12.3521 0.1333 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0015 5.6224 0.8024 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2992 6.3467 1.1663 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0683 7.7974 1.1607 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.3359 8.5328 1.2709 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0471 10.0341 1.3417 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3060 10.4449 0.1410 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.0384 9.7095 0.0308 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3272 8.2082 -0.0399 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0751 11.8956 0.1355 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7432 -4.4532 -1.3549 F 0 0 0 0 0 0 0 0 0 0 0 0 -3.1378 1.9858 0.9610 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9657 -0.5524 -0.2023 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3441 -2.4898 1.0972 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0132 3.8634 0.0789 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5664 3.7989 1.8007 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2288 1.8925 -0.7100 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6210 0.5765 0.3230 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1662 0.6405 -1.3967 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7435 -2.4336 -0.2897 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8252 -4.2529 1.4073 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9329 -6.7025 1.5745 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4517 -7.0234 -1.0414 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7464 -11.0781 2.3489 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3541 -13.4646 2.1107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5176 -14.3007 0.7012 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9423 -12.7210 -0.4847 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2302 5.8704 1.5316 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6770 5.9349 -0.1902 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0704 6.0987 0.4371 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6236 6.0342 2.1588 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9554 8.3223 0.3991 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.8603 8.2203 2.1740 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9873 10.5832 1.3943 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4505 10.2483 2.2284 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5140 10.0219 -0.8722 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4189 9.9200 0.9026 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3870 7.6591 -0.0925 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9238 7.9940 -0.9266 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4965 12.1748 1.0160 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5249 12.1725 -0.7637 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0328 12.4160 0.1501 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 15 16 1 0 0 0 0 15 49 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 51 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 52 1 0 0 0 0 21 40 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 M END > 691711 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 10 > 2009 > 691711 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 10 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 43 46 0 0 0 999 V2000 -0.0165 1.3634 0.0095 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2579 1.7989 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1263 0.7032 -0.0145 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4128 -0.4041 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9344 -1.7858 -0.0264 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6875 -3.0118 0.0438 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4521 -3.4728 0.0292 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4086 -2.6697 0.0224 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5771 -1.2826 0.0307 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8760 -0.7583 0.0463 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9424 -1.6466 0.0528 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4074 -0.3858 0.0236 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1670 -0.9003 0.0091 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2614 -2.1275 -0.0409 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1978 -2.8701 -0.0200 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9980 -3.9648 -0.0299 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3277 -3.5074 -0.0434 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3727 -4.4202 -0.0561 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0978 -5.7762 -0.0553 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7805 -6.2268 -0.0424 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7423 -5.3402 -0.0283 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1192 -6.6732 -0.0677 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7665 -8.0580 -0.0661 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.2210 -1.1858 0.0684 O 0 0 0 0 0 0 0 0 0 0 0 0 -8.2630 -2.1638 0.0742 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8991 1.9855 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5312 2.7296 0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5142 -3.7068 0.0444 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4127 -3.0872 0.0108 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0431 0.3087 0.0534 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5478 0.6850 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0266 -1.9711 0.0026 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0136 -1.5150 -0.0484 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3956 -4.0739 -0.0668 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5780 -7.2876 -0.0422 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7242 -5.7004 -0.0180 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1884 -8.2847 0.8298 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1694 -8.2818 -0.9501 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6726 -8.6637 -0.0768 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1855 -2.7826 -0.8197 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1671 -2.7915 0.9601 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.2311 -1.6631 0.0868 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 27 1 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 4 6 1 0 0 0 0 5 14 1 0 0 0 0 6 15 1 0 0 0 0 6 16 2 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 7 29 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 30 1 0 0 0 0 10 13 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 31 1 0 0 0 0 12 25 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 33 1 0 0 0 0 15 18 1 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 35 1 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 36 1 0 0 0 0 22 37 1 0 0 0 0 23 24 1 0 0 0 0 24 38 1 0 0 0 0 24 39 1 0 0 0 0 24 40 1 0 0 0 0 25 26 1 0 0 0 0 26 41 1 0 0 0 0 26 42 1 0 0 0 0 26 43 1 0 0 0 0 M END > 510942 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2e > 2007 > 510942 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2e > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 0.0686 1.3129 0.6451 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2413 2.0585 0.4604 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4106 1.4450 0.0687 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0607 -0.0378 0.4410 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2362 -0.6856 0.0430 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4254 0.0615 -0.1460 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5386 -0.5840 -0.5277 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5219 -1.8813 -0.7209 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4357 -2.6195 -0.5567 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2824 -2.0821 -0.1813 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2241 3.4007 0.6694 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4504 4.1050 0.4643 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1572 -2.8645 -0.0135 N 0 0 0 0 0 0 0 0 0 0 0 0 0.2492 -4.2519 -0.1262 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4108 -4.9051 0.2722 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5027 -6.2754 0.1670 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4278 -7.0091 -0.3398 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7373 -6.3504 -0.7386 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8230 -4.9799 -0.6315 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5234 -8.4790 -0.4544 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4109 -9.2455 -0.9083 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9284 -9.4327 0.0011 S 0 0 0 0 0 0 0 0 0 0 0 0 1.1006 -10.9094 -0.4872 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1727 -10.5677 -0.9564 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0224 -11.6031 -1.4057 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6009 -12.9084 -1.3786 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6659 -13.2330 -0.9102 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5112 -12.2410 -0.4678 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2368 5.5937 0.7457 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5498 6.3477 0.5261 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3448 7.7770 0.7963 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6260 8.4962 0.8279 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3644 9.9902 1.0322 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6216 10.1881 2.2847 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3404 9.4690 2.2531 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6020 7.9749 2.0488 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4166 11.6174 2.5550 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6607 -14.1660 -1.9342 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -1.0723 1.9404 1.0371 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2328 1.1256 1.2142 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3095 2.0269 -0.0720 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8479 -0.6031 0.5863 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4353 -2.3689 -1.0280 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2117 3.7132 1.1389 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7767 3.9735 -0.5674 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6973 -2.4495 0.1827 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2417 -4.3372 0.6641 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4051 -6.7820 0.4759 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5703 -6.9151 -1.1306 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7255 -4.4704 -0.9356 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0100 -11.3656 -1.7726 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9876 -14.2638 -0.8932 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4956 -12.4955 -0.1037 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4756 5.9854 0.0711 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9105 5.7252 1.7774 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3111 5.9560 1.2007 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8762 6.2162 -0.5056 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2351 8.1180 1.6490 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1515 8.3445 -0.1149 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3145 10.5219 1.0850 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7783 10.3743 0.1973 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8149 9.6206 3.1959 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7313 9.8471 1.4320 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6519 7.4433 1.9961 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1881 7.5909 2.8837 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8496 12.0640 1.7381 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8645 11.7353 3.4874 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3834 12.1135 2.6399 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0703 1.7491 1.5269 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4779 0.6330 0.2732 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0353 0.3729 1.9775 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 39 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 13 46 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 47 1 0 0 0 0 16 17 2 0 0 0 0 16 48 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 49 1 0 0 0 0 19 50 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 51 1 0 0 0 0 26 27 1 0 0 0 0 26 38 1 0 0 0 0 27 28 2 0 0 0 0 27 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 62 1 0 0 0 0 35 63 1 0 0 0 0 36 64 1 0 0 0 0 36 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 39 40 1 0 0 0 0 40 69 1 0 0 0 0 40 70 1 0 0 0 0 40 71 1 0 0 0 0 M END > 691760 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 19 > 2009 > 691760 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 19 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 47 50 0 0 0 0 0 0 0 0999 V2000 -0.0178 1.4634 0.0101 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1205 2.2627 0.0309 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6980 3.6679 0.0325 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6443 3.7493 0.0131 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1813 2.3833 0.0036 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5223 1.7890 0.0490 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1859 1.2617 1.1089 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4636 0.9468 0.7422 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4699 1.8040 -1.0775 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6693 1.2643 -0.5829 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7657 1.1497 -1.4324 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6630 1.5645 -2.7420 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4753 2.0966 -3.2244 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3886 2.2225 -2.4047 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5126 -0.6933 -1.1050 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5347 -2.0749 -1.1061 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0502 -2.7819 -0.0086 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4588 -2.1005 1.0941 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4842 -0.7189 1.1036 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9312 -2.7957 2.1633 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.4388 -2.0332 3.2601 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0737 -4.1413 -0.0137 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2453 -4.7718 0.5077 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0299 -2.7452 -2.1809 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5098 -1.9572 -3.2721 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4531 4.6216 0.0487 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1660 4.5671 0.0100 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7953 2.2153 0.8883 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7693 2.2175 -0.8991 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7671 1.1132 2.0933 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1294 0.5559 1.3293 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6939 0.7365 -1.0662 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5136 1.4709 -3.4009 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4104 2.4170 -4.2537 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4675 2.6378 -2.7863 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8883 -0.1457 -1.9567 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8787 -0.1912 1.9593 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6496 -1.3921 3.6530 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2714 -1.4174 2.9200 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7825 -2.7083 4.0438 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1139 -4.4616 -0.0732 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3817 -4.4805 1.5491 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1339 -5.8543 0.4448 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8760 -2.6141 -4.0612 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6986 -1.3410 -3.6597 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3210 -1.3156 -2.9279 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 6 1 0 0 0 0 3 4 1 0 0 0 0 3 27 2 0 0 0 0 4 5 1 0 0 0 0 4 28 1 0 0 0 0 5 29 1 0 0 0 0 5 30 1 0 0 0 0 6 9 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 31 1 0 0 0 0 8 10 1 0 0 0 0 8 32 1 0 0 0 0 9 14 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 33 1 0 0 0 0 12 13 1 0 0 0 0 12 34 1 0 0 0 0 13 14 2 0 0 0 0 13 35 1 0 0 0 0 14 36 1 0 0 0 0 15 16 2 0 0 0 0 15 20 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 17 18 2 0 0 0 0 17 25 1 0 0 0 0 18 19 1 0 0 0 0 18 23 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 20 38 1 0 0 0 0 21 22 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 24 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 M END > 549128 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 3 > 2008 > 549128 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 3 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 -0.0882 1.3544 0.6744 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0574 -0.0396 0.5300 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1957 -0.7370 0.1910 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2490 2.0501 0.4880 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4214 1.3642 0.1490 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3953 -0.0436 -0.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5295 -0.6750 -0.3521 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.6384 0.0017 -0.5342 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7102 1.3162 -0.3970 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.6484 2.0373 -0.0613 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1079 -0.7098 0.7260 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0751 -2.1292 0.5637 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7380 3.4077 0.0786 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.9801 4.0391 -0.0125 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.4468 5.2918 -0.1945 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.2912 5.9617 -0.6034 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0655 5.3365 -0.5126 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.7620 5.9581 -0.2911 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.8849 5.4275 0.0602 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.0194 7.5895 -0.8942 S 0 0 0 0 0 0 0 0 0 0 0 0 -10.7521 7.4323 -0.6175 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.0012 6.1630 -0.0829 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.3352 5.8149 0.2245 C 0 0 0 0 0 0 0 0 0 0 0 0 -13.3478 6.6986 0.0102 C 0 0 0 0 0 0 0 0 0 0 0 0 -13.0919 7.9590 -0.5142 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.8020 8.3231 -0.8330 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4690 -2.7044 0.8229 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4340 -4.2241 0.6490 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7722 -4.7764 0.8979 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7307 -6.2434 0.9742 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1517 -6.7826 1.1543 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7388 -6.2111 2.3742 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7804 -4.7441 2.2979 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3594 -4.2049 2.1178 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0771 -6.7634 2.6230 C 0 0 0 0 0 0 0 0 0 0 0 0 -14.3987 9.0705 -0.7800 Cl 0 0 0 0 0 0 0 0 0 0 0 0 1.0487 2.0210 1.0093 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9533 3.4407 1.1416 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.1296 3.3699 0.3905 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3573 3.9897 0.3011 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9470 5.9826 -0.9084 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.1632 -1.8109 0.0811 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2642 3.1230 0.6105 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5328 -0.5379 -0.8086 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3670 -2.5596 1.2718 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7653 -2.3715 -0.4529 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9381 3.9321 0.2403 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.3578 6.9676 -0.9910 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.5535 4.8391 0.6326 H 0 0 0 0 0 0 0 0 0 0 0 0 -14.3623 6.4164 0.2504 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.6030 9.3032 -1.2407 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1771 -2.2739 0.1148 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7788 -2.4620 1.8394 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7258 -4.6545 1.3571 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1241 -4.4665 -0.3675 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1167 -6.5462 1.8223 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3038 -6.6434 0.0545 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1203 -7.8688 1.2402 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7586 -6.5030 0.2931 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2073 -4.3441 3.2176 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3944 -4.4413 1.4497 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3907 -3.1187 2.0319 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7525 -4.4845 2.9790 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7283 -6.5318 1.7802 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4885 -6.3236 3.5316 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0076 -7.8446 2.7421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9284 3.8468 1.4108 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6285 3.8728 0.1951 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2304 3.6853 1.9198 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0607 2.3626 0.7740 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.2493 3.4698 0.6182 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 37 1 0 0 0 0 1 4 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 42 1 0 0 0 0 4 5 2 0 0 0 0 4 43 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 44 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 27 1 0 0 0 0 12 45 1 0 0 0 0 12 46 1 0 0 0 0 13 14 1 0 0 0 0 13 47 1 0 0 0 0 14 17 1 0 0 0 0 14 39 2 0 0 0 0 15 18 1 0 0 0 0 15 40 2 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 48 1 0 0 0 0 17 41 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 26 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 49 1 0 0 0 0 24 25 1 0 0 0 0 24 50 1 0 0 0 0 25 26 2 0 0 0 0 25 36 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 29 30 1 0 0 0 0 29 34 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 58 1 0 0 0 0 31 59 1 0 0 0 0 32 33 1 0 0 0 0 32 35 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 62 1 0 0 0 0 34 63 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 35 66 1 0 0 0 0 37 38 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 38 69 1 0 0 0 0 39 40 1 0 0 0 0 39 70 1 0 0 0 0 40 71 1 0 0 0 0 M END > 691762 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 21 > 2009 > 691762 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 21 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 53 56 0 0 0 0 0 0 0 0999 V2000 0.0875 1.3653 0.0116 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2771 -0.0133 -0.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5146 -0.4947 -0.1183 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5620 0.3225 -0.1361 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4174 1.6422 -0.0828 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2089 2.1918 -0.0092 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0664 3.5705 0.0461 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1989 4.3879 0.1519 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5181 3.9484 0.3484 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3161 5.0392 0.3954 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5370 6.1296 0.2353 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2135 5.6982 0.0790 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8102 5.0376 0.5922 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9169 -0.2487 -0.2165 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9804 0.5612 -0.3487 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3245 -0.0127 -0.5373 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4333 0.8267 -0.6752 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6883 0.2824 -0.8510 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8510 -1.0912 -0.8914 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7577 -1.9287 -0.7560 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4975 -1.3990 -0.5734 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8106 -0.8728 -0.0272 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3753 -2.2747 -0.0966 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5967 -3.1911 0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5333 -2.8790 -1.0822 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.9686 -1.4771 -1.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7471 -0.5607 -1.1159 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6857 -3.7898 -1.0624 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9064 1.7843 0.0665 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1825 3.9685 0.0115 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8383 2.9216 0.4455 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8408 7.0507 0.2264 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3044 4.9830 -0.3779 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1106 5.9530 1.1019 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0964 4.1755 1.1947 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0555 -1.3187 -0.1692 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8504 1.6328 -0.3167 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3078 1.8989 -0.6446 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5461 0.9298 -0.9577 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8361 -1.5118 -1.0296 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8922 -2.9998 -0.7893 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6451 -2.0537 -0.4679 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1329 -2.4512 -1.0446 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3074 -2.4846 0.7269 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2792 -4.2307 -0.0738 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0893 -3.0340 0.9661 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6512 -1.2672 -1.8363 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4767 -1.3006 -0.0648 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0647 0.4789 -1.0356 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2546 -0.7178 -2.0755 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2099 -3.6920 -0.1118 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3628 -3.5367 -1.8783 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3397 -4.8163 -1.1827 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 29 1 0 0 0 0 2 3 1 0 0 0 0 2 22 1 0 0 0 0 3 4 2 0 0 0 0 4 14 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 30 1 0 0 0 0 8 9 1 0 0 0 0 8 12 2 0 0 0 0 9 10 2 0 0 0 0 9 31 1 0 0 0 0 10 11 1 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 11 32 1 0 0 0 0 13 33 1 0 0 0 0 13 34 1 0 0 0 0 13 35 1 0 0 0 0 14 15 2 0 0 0 0 14 36 1 0 0 0 0 15 16 1 0 0 0 0 15 37 1 0 0 0 0 16 17 2 0 0 0 0 16 21 1 0 0 0 0 17 18 1 0 0 0 0 17 38 1 0 0 0 0 18 19 2 0 0 0 0 18 39 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 20 21 2 0 0 0 0 20 41 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 26 1 0 0 0 0 25 28 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 M END > 620121 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19320489 > J. Med. Chem.|2009|52|9|2629 > "14, ENMD-2076" > 2009 > 620121 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19320489 > J. Med. Chem.|2009|52|9|2629 > "14, ENMD-2076" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 46 49 0 0 0 999 V2000 2.0645 1.0433 -1.6952 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9631 -0.3041 -1.5207 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0331 -0.8726 -0.2548 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2094 -0.0786 0.8683 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2440 1.8873 -0.5846 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3184 1.3267 0.7138 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4977 2.1656 1.8220 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5997 3.5117 1.6451 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5280 4.0748 0.3679 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3515 3.2791 -0.7414 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2824 -0.6890 2.2088 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0869 -2.0142 2.3573 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5189 0.0033 3.1801 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6322 5.4214 0.2198 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8595 5.9820 0.3447 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3771 7.1059 0.6021 N 0 0 0 0 0 0 0 0 0 0 0 0 6.2331 5.8011 0.6315 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9893 5.1979 0.5060 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3317 7.9251 0.4438 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0269 7.3863 0.3086 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9322 8.2410 0.1423 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1353 9.6126 0.1113 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4365 10.1420 0.2461 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5111 9.3181 0.4082 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6205 11.4859 0.2135 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9608 11.9608 0.3552 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9869 10.5214 -0.0636 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1622 11.7244 -0.0911 O 0 0 0 0 0 0 0 0 0 0 0 0 0.7431 10.0186 -0.1931 N 0 0 0 0 0 0 0 0 0 0 0 0 2.0114 1.4636 -2.6886 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8254 -0.9416 -2.3816 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9491 -1.9437 -0.1444 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5546 1.7448 2.8150 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7375 4.1529 2.5032 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2967 3.7215 -1.7251 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8983 -2.5665 1.5825 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1349 -2.4158 3.2390 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1068 5.1797 0.7615 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9030 4.1217 0.5345 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9364 7.8359 0.0384 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5013 9.7371 0.5098 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3628 11.6333 1.3140 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5750 11.5614 -0.4518 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9669 13.0499 0.3117 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6033 9.0590 -0.1711 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0121 10.6163 -0.3081 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 30 1 0 0 0 0 2 3 1 0 0 0 0 2 31 1 0 0 0 0 3 4 2 0 0 0 0 3 32 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 33 1 0 0 0 0 8 9 2 0 0 0 0 8 34 1 0 0 0 0 9 14 1 0 0 0 0 9 10 1 0 0 0 0 10 35 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 36 1 0 0 0 0 12 37 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 27 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 24 41 1 0 0 0 0 25 26 1 0 0 0 0 26 42 1 0 0 0 0 26 43 1 0 0 0 0 26 44 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 29 45 1 0 0 0 0 29 46 1 0 0 0 0 M END > 541051 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 31 > 2008 > 541051 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 31 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 58 61 0 0 0 999 V2000 0.2207 1.0332 0.1701 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2352 0.5695 1.4124 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4105 0.9081 2.5665 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3226 1.8346 0.0880 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0058 2.1977 1.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5476 1.7313 2.5146 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1976 2.0762 3.6325 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2613 2.8441 3.6010 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7709 3.3411 2.4080 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1502 3.0252 1.2123 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4382 0.6765 -0.9646 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.3347 -0.2271 1.4683 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7512 -0.6681 2.7621 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0754 1.1813 -2.1989 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6255 3.4956 0.0327 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7909 4.1940 0.0475 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7650 5.5528 -0.0933 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1842 4.1876 0.2310 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0012 3.5139 0.2122 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1937 5.5817 0.0833 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9696 6.2756 -0.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9794 7.6742 -0.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1597 8.3553 -0.2037 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3701 7.6922 -0.0468 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4077 6.3130 0.0969 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6964 5.6156 0.2631 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8512 6.3063 0.1867 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7171 4.4174 0.4690 O 0 0 0 0 0 0 0 0 0 0 0 0 12.1314 5.6135 0.3518 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2720 4.5378 -0.7272 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2765 6.6198 0.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1827 4.9592 1.7339 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0481 0.5444 3.5166 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6672 2.1867 -0.8730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7541 3.0968 4.5282 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6478 3.9716 2.4138 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9493 -1.2428 3.2257 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9843 0.1968 3.3832 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6377 -1.2948 2.6644 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5411 0.8221 -3.0229 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0588 2.2710 -2.1808 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1002 0.8357 -2.3344 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8238 6.0682 -0.2159 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1123 3.6494 0.3550 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9977 2.4400 0.3265 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0498 8.2098 -0.3449 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1538 9.4296 -0.3144 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2912 8.2561 -0.0370 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8347 7.2622 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2354 5.0039 -1.7118 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2245 4.0223 -0.6043 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4562 3.8209 -0.6340 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1763 7.3861 0.9897 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2290 6.1043 0.3438 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2399 7.0858 -0.7636 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3670 4.2423 1.8271 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1353 4.4438 1.8567 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0826 5.7256 2.5026 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 33 1 0 0 0 0 4 5 2 0 0 0 0 4 34 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 35 1 0 0 0 0 9 10 2 0 0 0 0 9 36 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 14 40 1 0 0 0 0 14 41 1 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 43 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 44 1 0 0 0 0 19 45 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 23 24 2 0 0 0 0 23 47 1 0 0 0 0 24 25 1 0 0 0 0 24 48 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 49 1 0 0 0 0 29 30 1 0 0 0 0 29 31 1 0 0 0 0 29 32 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 32 56 1 0 0 0 0 32 57 1 0 0 0 0 32 58 1 0 0 0 0 M END > 540605 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 18 > 2008 > 540605 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 18 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 45 49 0 0 0 999 V2000 -0.0166 1.3739 0.0096 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2592 1.8054 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1254 0.7084 -0.0144 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4143 -0.4002 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9394 -1.7804 -0.0260 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7088 -3.0550 0.0393 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4661 -3.4741 0.0256 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4194 -2.6664 0.0204 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5737 -1.2837 0.0293 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4085 -0.3878 0.0230 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1650 -0.9014 0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2674 -2.1188 -0.0345 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2054 -2.8666 -0.0248 N 0 0 0 0 0 0 0 0 0 0 0 0 2.0084 -3.9592 -0.0379 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3370 -3.4985 -0.0444 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3843 -4.4088 -0.0556 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1127 -5.7654 -0.0637 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7964 -6.2192 -0.0606 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7560 -5.3353 -0.0426 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1363 -6.6599 -0.0751 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7870 -8.0455 -0.0830 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0083 -1.6830 0.0494 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9377 -0.7530 0.0447 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2078 0.6172 0.0551 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.5034 1.0452 0.0696 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.5581 0.1355 0.0743 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3290 -1.2074 0.0649 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8983 1.9974 0.0254 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5348 2.7354 0.0016 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5134 -3.7754 0.0382 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4252 -3.0881 0.0094 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5505 0.6828 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0231 -1.9721 0.0012 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0180 -1.5045 -0.0341 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4064 -4.0600 -0.0583 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5965 -7.2806 -0.0674 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7388 -5.6980 -0.0404 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1955 -8.2660 -0.9716 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6947 -8.6490 -0.0918 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2045 -8.2784 0.8083 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3982 1.3319 0.0519 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.7139 2.1045 0.0780 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.5744 0.5008 0.0859 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1571 -1.9007 0.0684 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 29 1 0 0 0 0 2 3 1 0 0 0 0 2 30 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 12 1 0 0 0 0 6 14 2 0 0 0 0 6 13 1 0 0 0 0 7 8 2 0 0 0 0 7 23 1 0 0 0 0 7 31 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 32 1 0 0 0 0 10 24 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 33 1 0 0 0 0 12 34 1 0 0 0 0 13 16 1 0 0 0 0 13 35 1 0 0 0 0 14 15 1 0 0 0 0 15 16 2 0 0 0 0 15 20 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 36 1 0 0 0 0 18 19 1 0 0 0 0 18 21 1 0 0 0 0 19 20 2 0 0 0 0 19 37 1 0 0 0 0 20 38 1 0 0 0 0 21 22 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 42 1 0 0 0 0 26 27 1 0 0 0 0 26 43 1 0 0 0 0 27 28 2 0 0 0 0 27 44 1 0 0 0 0 28 45 1 0 0 0 0 M END > 510939 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2c > 2007 > 510939 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2c > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 55 0 0 0 0 0 0 0 0999 V2000 0.2054 1.0948 -0.4729 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1013 -0.0936 0.2633 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1036 -0.4761 1.1271 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3030 1.8985 -0.3496 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3361 1.5323 0.5214 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2377 0.3326 1.2691 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2423 0.0043 2.0966 N 0 0 0 0 0 0 0 0 0 0 0 0 4.2930 0.7818 2.2081 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4280 1.9108 1.5307 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4944 2.3284 0.6859 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0003 -0.8762 0.1235 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.0476 -2.0745 0.9007 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7949 1.4486 -1.3234 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.6305 2.6708 -2.0455 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6485 3.5087 -0.0139 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8474 4.2171 0.0686 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0448 3.5351 0.2563 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2305 4.2319 0.3381 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2291 5.6243 0.2324 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0248 6.3063 0.0439 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8434 5.6038 -0.0428 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4988 6.3746 0.3202 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6609 5.8397 0.4932 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6432 8.1225 0.1965 S 0 0 0 0 0 0 0 0 0 0 0 0 10.3890 8.0057 0.4014 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7278 6.6556 0.5475 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0886 6.3220 0.7271 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0409 7.2940 0.7569 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6965 8.6306 0.6117 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3786 8.9865 0.4334 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5437 6.3388 -0.2462 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0151 -1.3929 1.6911 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3739 2.8118 -0.9217 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0830 0.4876 2.8831 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2015 -2.7103 0.6399 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9998 -1.8226 1.9601 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9775 -2.6046 0.6948 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4974 2.8338 -2.6859 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5374 3.4985 -1.3424 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2685 2.6123 -2.6589 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9230 3.8453 -0.5628 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0452 2.4582 0.3384 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1600 3.7018 0.4843 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0206 7.3832 -0.0379 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3757 5.2873 0.8421 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0769 7.0219 0.8954 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4625 9.3915 0.6381 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1112 10.0268 0.3205 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3484 6.4431 -1.3135 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7326 5.7782 0.2184 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6099 7.3269 0.2093 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 32 1 0 0 0 0 4 5 2 0 0 0 0 4 33 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 34 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 12 37 1 0 0 0 0 13 14 1 0 0 0 0 14 38 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 15 16 1 0 0 0 0 15 41 1 0 0 0 0 16 17 2 0 0 0 0 16 21 1 0 0 0 0 17 18 1 0 0 0 0 17 42 1 0 0 0 0 18 19 2 0 0 0 0 18 43 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 44 1 0 0 0 0 21 31 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 28 46 1 0 0 0 0 29 30 2 0 0 0 0 29 47 1 0 0 0 0 30 48 1 0 0 0 0 31 49 1 0 0 0 0 31 50 1 0 0 0 0 31 51 1 0 0 0 0 M END > 557701 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "26, Table 4" > 2009 > 557701 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "26, Table 4" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 55 58 0 0 0 999 V2000 0.2207 1.0332 0.1701 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2352 0.5695 1.4124 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4105 0.9081 2.5665 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3226 1.8346 0.0880 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0058 2.1977 1.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5476 1.7312 2.5146 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1976 2.0762 3.6325 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2613 2.8441 3.6010 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7709 3.3411 2.4080 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1502 3.0252 1.2123 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4382 0.6765 -0.9646 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.3347 -0.2271 1.4683 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7512 -0.6681 2.7621 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0754 1.1813 -2.1989 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6255 3.4956 0.0327 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7909 4.1940 0.0475 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7650 5.5528 -0.0933 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1842 4.1876 0.2310 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0012 3.5139 0.2122 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1937 5.5817 0.0833 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9696 6.2756 -0.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9794 7.6742 -0.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1597 8.3553 -0.2037 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3701 7.6922 -0.0468 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4077 6.3130 0.0969 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6964 5.6156 0.2631 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8512 6.3063 0.1867 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7171 4.4174 0.4690 O 0 0 0 0 0 0 0 0 0 0 0 0 12.1314 5.6135 0.3518 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5675 5.0212 -0.9898 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1892 6.6057 0.8391 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0481 0.5444 3.5166 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6672 2.1867 -0.8730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7541 3.0968 4.5282 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6478 3.9716 2.4138 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9493 -1.2428 3.2257 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9843 0.1968 3.3832 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6377 -1.2948 2.6644 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5411 0.8221 -3.0229 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0588 2.2710 -2.1809 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1002 0.8357 -2.3344 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8238 6.0682 -0.2159 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1123 3.6494 0.3550 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9977 2.4400 0.3265 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0498 8.2098 -0.3449 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1538 9.4296 -0.3144 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2912 8.2561 -0.0370 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8347 7.2622 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0197 4.8131 1.0832 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5200 4.5057 -0.8670 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8139 4.3143 -1.3370 H 0 0 0 0 0 0 0 0 0 0 0 0 12.6792 5.8216 -1.7212 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8785 7.0277 1.7949 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1417 6.0902 0.9620 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3009 7.4061 0.1077 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 32 1 0 0 0 0 4 5 2 0 0 0 0 4 33 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 34 1 0 0 0 0 9 10 2 0 0 0 0 9 35 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 14 41 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 42 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 43 1 0 0 0 0 19 44 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 45 1 0 0 0 0 23 24 2 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 48 1 0 0 0 0 29 30 1 0 0 0 0 29 31 1 0 0 0 0 29 49 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > 540604 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 17 > 2008 > 540604 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 17 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 50 53 0 0 0 999 V2000 -0.0165 1.3634 0.0095 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2579 1.7989 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1264 0.7032 -0.0145 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4128 -0.4041 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9344 -1.7858 -0.0267 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6891 -3.0042 0.0427 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4550 -3.4699 0.0281 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4093 -2.6695 0.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5770 -1.2825 0.0301 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8770 -0.7586 0.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9400 -1.6435 0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4074 -0.3858 0.0233 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1670 -0.9003 0.0088 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2614 -2.1275 -0.0416 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1978 -2.8701 -0.0202 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9980 -3.9648 -0.0304 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3277 -3.5074 -0.0441 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3727 -4.4202 -0.0567 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0978 -5.7762 -0.0555 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7805 -6.2268 -0.0419 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7423 -5.3402 -0.0290 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1192 -6.6732 -0.0682 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7665 -8.0580 -0.0663 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3570 -1.1308 0.0688 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.8313 -0.9573 -1.3107 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.2125 -0.4576 -1.3335 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.6703 -0.2900 -2.7838 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8991 1.9855 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5312 2.7296 0.0018 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5178 -3.6968 0.0431 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4140 -3.0886 0.0099 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0442 0.3084 0.0531 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5478 0.6850 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0266 -1.9711 0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0136 -1.5150 -0.0492 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3956 -4.0739 -0.0677 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5780 -7.2876 -0.0414 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7242 -5.7004 -0.0181 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1889 -8.2845 0.8299 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1689 -8.2820 -0.9499 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6726 -8.6637 -0.0773 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.9963 -1.8467 0.5855 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.3907 -0.1729 0.5877 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.2176 -0.3478 -1.8301 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.8647 -1.1688 -0.8265 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.2591 0.5050 -0.8243 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.6952 0.0808 -2.8008 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.0182 0.4212 -3.2908 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.6237 -1.2526 -3.2930 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 29 1 0 0 0 0 2 3 1 0 0 0 0 2 30 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 4 6 1 0 0 0 0 5 14 1 0 0 0 0 6 15 1 0 0 0 0 6 16 2 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 7 31 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 32 1 0 0 0 0 10 11 1 0 0 0 0 10 13 1 0 0 0 0 11 12 2 0 0 0 0 11 33 1 0 0 0 0 12 25 1 0 0 0 0 13 14 2 0 0 0 0 13 34 1 0 0 0 0 14 35 1 0 0 0 0 15 18 1 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 37 1 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 24 40 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 26 27 1 0 0 0 0 26 45 1 0 0 0 0 27 28 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 28 50 1 0 0 0 0 M END > 510945 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2h > 2007 > 510945 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2h > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 49 53 0 0 0 999 V2000 0.7107 1.0374 -0.2942 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8457 -0.3105 -0.1487 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0610 -0.8761 0.2173 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1723 -0.0786 0.4446 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8112 1.8849 -0.0743 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0584 1.3273 0.2993 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1564 2.1697 0.5194 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0192 3.5163 0.3729 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7928 4.0765 0.0045 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6947 3.2772 -0.2191 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4587 -0.6859 0.8336 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5368 -2.0125 1.0587 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4488 0.0101 0.9514 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6833 5.4238 -0.1338 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2210 5.9959 -1.2388 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3238 7.1421 -3.5048 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3088 5.8364 -3.3701 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7653 5.2223 -2.2495 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8107 7.9498 -2.5697 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2379 7.3999 -1.3970 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6998 8.2488 -0.4181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7306 9.5968 -0.5996 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2937 10.1505 -1.7535 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8292 9.3447 -2.7321 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3121 11.4996 -1.9105 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7408 12.2828 -0.8606 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8147 -2.6158 1.4452 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7674 -3.9258 2.2342 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2083 -3.9306 0.7691 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2422 1.4554 -0.5834 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0071 -0.9506 -0.3204 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1407 -1.9477 0.3261 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1102 1.7513 0.8051 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8692 4.1602 0.5439 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7504 3.7173 -0.5038 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7470 -2.5677 0.9648 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7342 5.2230 -4.1506 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7676 4.1455 -2.1667 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2617 7.8331 0.4774 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3150 10.2467 0.1562 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2618 9.7824 -3.6196 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6909 12.0164 -0.7386 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2753 12.0889 0.0694 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8204 13.3405 -1.1117 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6133 -1.9133 1.6836 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5352 -4.0853 2.9913 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7856 -4.3388 2.4657 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5165 -4.3468 0.0367 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2661 -4.0933 0.5623 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 30 1 0 0 0 0 2 3 1 0 0 0 0 2 31 1 0 0 0 0 3 4 2 0 0 0 0 3 32 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 33 1 0 0 0 0 8 9 2 0 0 0 0 8 34 1 0 0 0 0 9 14 1 0 0 0 0 9 10 1 0 0 0 0 10 35 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 27 1 0 0 0 0 12 36 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 37 1 0 0 0 0 18 38 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 39 1 0 0 0 0 22 23 1 0 0 0 0 22 40 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 24 41 1 0 0 0 0 25 26 1 0 0 0 0 26 42 1 0 0 0 0 26 43 1 0 0 0 0 26 44 1 0 0 0 0 27 28 1 0 0 0 0 27 29 1 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 28 46 1 0 0 0 0 28 47 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 M END > 541099 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 26 > 2008 > 541099 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 26 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 77 83 0 0 0 0 0 0 0 0999 V2000 -0.1003 1.3298 -0.3684 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0894 2.0144 -0.5526 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2826 1.3159 -0.5491 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3071 0.0088 -0.3733 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1993 -0.6904 -0.1934 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0483 -0.0537 -0.1844 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2715 -2.0322 -0.0170 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4875 -2.6272 -0.1378 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8026 -3.3162 -1.2744 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0438 -3.9285 -1.4211 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9895 -3.8553 -0.4217 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4286 -2.5298 0.9071 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6942 -3.1502 0.7647 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6304 -3.0532 1.8058 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3116 -2.3651 2.9370 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0675 -1.7544 3.0774 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1371 -1.8238 2.0854 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2912 -0.8343 0.0170 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5362 -0.1983 0.0200 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6693 -0.9693 0.2061 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5431 -2.2763 0.3744 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.3500 -2.8532 0.3670 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2403 -2.1535 0.1924 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.2621 -4.2228 0.5471 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4786 -5.0154 0.7425 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1049 -6.4889 0.9161 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3613 -7.3002 1.2443 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9915 -8.7810 1.3566 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4087 -9.2388 0.0889 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.1748 -8.5064 -0.2234 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4904 -7.0174 -0.3829 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1690 -10.6879 0.1126 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8006 -11.1670 -1.2929 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2318 -4.4750 -0.5815 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5683 -5.0438 -1.7927 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7075 -5.7573 -2.0351 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8403 -4.9849 -2.8800 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4674 -5.6494 -3.8856 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6696 -6.1530 -3.3619 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5243 -6.8856 -4.1715 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1924 -7.1145 -5.4909 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0085 -6.6160 -6.0143 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1439 -5.8939 -5.2227 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0448 1.8536 -0.3628 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0851 3.0845 -0.6981 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2104 1.8496 -0.6931 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0773 -3.3872 -2.0714 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2684 -4.4680 -2.3293 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5986 -3.5221 1.7105 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0336 -2.2921 3.7369 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8390 -1.2145 3.9844 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1767 -1.3452 2.2077 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6113 0.8700 -0.1192 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6467 -0.5098 0.2142 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3952 -4.6578 0.5439 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0010 -4.6657 1.6330 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1276 -4.9051 -0.1262 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3845 -6.5887 1.7280 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7795 -6.9568 2.1904 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0973 -7.1681 0.4511 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2659 -8.9142 2.1590 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.8865 -9.3632 1.5761 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4577 -8.6409 0.5864 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7503 -8.8891 -1.1515 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1969 -6.8808 -1.2016 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5718 -6.4719 -0.5993 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3510 -10.9097 0.7981 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0715 -11.2001 0.4462 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6186 -10.9452 -1.9784 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8981 -10.6549 -1.6265 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6227 -12.2422 -1.2753 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8575 -4.5052 0.1591 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4120 -5.9506 -1.3970 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4479 -7.2758 -3.7703 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8590 -7.6852 -6.1205 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7598 -6.8016 -7.0488 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2236 -5.5090 -5.6366 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 44 1 0 0 0 0 2 3 1 0 0 0 0 2 45 1 0 0 0 0 3 4 2 0 0 0 0 3 46 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 12 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 47 1 0 0 0 0 10 11 2 0 0 0 0 10 48 1 0 0 0 0 11 13 1 0 0 0 0 11 34 1 0 0 0 0 12 13 1 0 0 0 0 12 17 2 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 49 1 0 0 0 0 15 16 2 0 0 0 0 15 50 1 0 0 0 0 16 17 1 0 0 0 0 16 51 1 0 0 0 0 17 52 1 0 0 0 0 18 23 1 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 19 53 1 0 0 0 0 20 21 2 0 0 0 0 20 54 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 24 25 1 0 0 0 0 24 55 1 0 0 0 0 25 26 1 0 0 0 0 25 56 1 0 0 0 0 25 57 1 0 0 0 0 26 27 1 0 0 0 0 26 31 1 0 0 0 0 26 58 1 0 0 0 0 27 28 1 0 0 0 0 27 59 1 0 0 0 0 27 60 1 0 0 0 0 28 29 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 29 30 1 0 0 0 0 29 32 1 0 0 0 0 30 31 1 0 0 0 0 30 63 1 0 0 0 0 30 64 1 0 0 0 0 31 65 1 0 0 0 0 31 66 1 0 0 0 0 32 33 1 0 0 0 0 32 67 1 0 0 0 0 32 68 1 0 0 0 0 33 69 1 0 0 0 0 33 70 1 0 0 0 0 33 71 1 0 0 0 0 34 35 1 0 0 0 0 34 72 1 0 0 0 0 35 36 1 0 0 0 0 35 37 2 0 0 0 0 36 39 1 0 0 0 0 36 73 1 0 0 0 0 37 38 1 0 0 0 0 38 39 2 0 0 0 0 38 43 1 0 0 0 0 39 40 1 0 0 0 0 40 41 2 0 0 0 0 40 74 1 0 0 0 0 41 42 1 0 0 0 0 41 75 1 0 0 0 0 42 43 2 0 0 0 0 42 76 1 0 0 0 0 43 77 1 0 0 0 0 M END > 731886 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 1 > 2010 > 731886 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 1 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 46 49 0 0 0 0 0 0 0 0999 V2000 -0.0167 1.3827 0.0096 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1975 -0.6903 -0.0126 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1636 2.0942 0.0022 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3786 1.4139 -0.0130 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3993 0.0094 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7213 -0.3863 -0.0351 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5395 0.6977 -0.0376 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7896 1.8402 -0.0242 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2911 3.2216 -0.0224 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8305 3.9161 -1.0975 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1750 5.2570 -0.5891 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8478 5.3230 0.7123 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3183 4.1588 1.1252 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0207 3.4134 -2.4724 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3097 3.9846 -3.5314 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4899 3.5115 -4.8182 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3785 2.4673 -5.0593 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0878 1.8960 -4.0063 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9164 2.3690 -2.7183 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9543 0.8755 -4.2455 O 0 0 0 0 0 0 0 0 0 0 0 0 7.6487 0.3365 -3.1189 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5537 2.0040 -6.3260 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5769 2.6237 -7.1077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7981 4.0666 -5.8490 O 0 0 0 0 0 0 0 0 0 0 0 0 2.9031 5.1338 -5.5296 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6734 6.1541 -1.2399 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9276 3.9160 2.2491 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9606 1.9075 0.0169 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9288 -0.5516 0.0079 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2008 -1.7703 -0.0177 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1464 3.1741 0.0074 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0234 -1.3081 -0.0422 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6188 0.6623 -0.0483 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9758 6.1024 1.2754 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6200 4.7945 -3.3449 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4671 1.9257 -1.9019 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3057 -0.4685 -3.4481 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2422 1.1206 -2.6487 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9278 -0.0537 -2.4004 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3608 3.6870 -7.2119 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5398 2.4954 -6.6131 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6107 2.1613 -8.0942 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4615 5.9531 -5.0769 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4167 5.4848 -6.4398 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1483 4.7775 -4.8286 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 29 1 0 0 0 0 2 3 1 0 0 0 0 2 30 1 0 0 0 0 3 6 2 0 0 0 0 3 31 1 0 0 0 0 4 5 2 0 0 0 0 4 32 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 33 1 0 0 0 0 8 9 2 0 0 0 0 8 34 1 0 0 0 0 9 10 1 0 0 0 0 10 14 1 0 0 0 0 10 11 2 0 0 0 0 11 15 1 0 0 0 0 11 12 1 0 0 0 0 12 27 2 0 0 0 0 12 13 1 0 0 0 0 13 14 1 0 0 0 0 13 35 1 0 0 0 0 14 28 2 0 0 0 0 15 16 2 0 0 0 0 15 20 1 0 0 0 0 16 17 1 0 0 0 0 16 36 1 0 0 0 0 17 18 2 0 0 0 0 17 25 1 0 0 0 0 18 19 1 0 0 0 0 18 23 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 20 37 1 0 0 0 0 21 22 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 26 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 M END > 438477 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 1 > 2008 > 438477 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 20031417 > Bioorg. Med. Chem.|2010|18|2|612 > "8, Maleimide" > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 55 0 0 0 0 0 0 0 0999 V2000 0.3502 1.5250 -1.1493 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2046 2.1057 -0.2179 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1083 1.3179 0.4871 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1600 -0.0405 0.2644 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3035 -0.6265 -0.6701 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3969 0.1672 -1.3762 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3567 -2.0831 -0.9117 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6103 -2.7191 -1.7512 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4509 -3.1961 -0.1021 S 0 0 0 0 0 0 0 0 0 0 0 0 1.7787 -4.5430 -1.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7800 -4.0479 -1.8637 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0970 -4.9595 -2.6991 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4075 -6.2845 -2.6765 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3991 -6.7674 -1.8341 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0830 -5.9030 -1.0092 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1553 3.4815 0.0092 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.0518 4.1555 -0.0803 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1650 3.4637 -0.2723 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.3384 4.0727 -0.3631 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3957 5.4483 -0.2554 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2055 6.1510 -0.0531 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0645 5.4752 0.0337 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2151 7.5316 0.0609 N 0 0 0 0 0 0 0 0 0 0 0 0 0.1433 8.0524 0.2682 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0997 9.5817 0.3094 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7977 10.0147 1.3895 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.1562 9.4939 1.1821 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1126 7.9646 1.1410 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8079 11.4787 1.5104 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3535 2.1387 -1.6920 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7704 1.7716 1.2097 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8624 -0.6516 0.8117 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2670 -0.2832 -2.0992 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6781 -4.6022 -3.3609 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1242 -6.9682 -3.3217 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6346 -7.8214 -1.8260 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8545 -6.2794 -0.3538 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9661 3.9660 0.2298 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2401 3.4995 -0.5201 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3393 5.9689 -0.3262 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5377 7.6743 1.2114 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7858 7.7288 -0.5507 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1020 9.9693 0.4920 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2690 9.9608 -0.6438 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7987 9.8175 2.0010 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5506 9.8720 0.2389 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1149 7.5770 0.9583 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7439 7.5855 2.0941 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1508 11.9182 0.5737 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4800 11.7720 2.3169 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1995 11.8321 1.7302 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 30 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 31 1 0 0 0 0 4 5 1 0 0 0 0 4 32 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 33 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 34 1 0 0 0 0 13 14 1 0 0 0 0 13 35 1 0 0 0 0 14 15 2 0 0 0 0 14 36 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 38 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 39 1 0 0 0 0 20 21 1 0 0 0 0 20 40 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 28 47 1 0 0 0 0 28 48 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > 557431 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "7, Table 2" > 2009 > 557431 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "7, Table 2" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 52 56 0 0 0 999 V2000 0.2184 1.6837 -0.0864 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0266 0.3349 -0.0959 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1009 -0.5448 -0.0419 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4019 -0.0691 0.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5204 2.2111 -0.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6284 1.3305 0.0337 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9263 1.8553 0.0987 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1103 3.2046 0.1078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0202 4.0773 0.0531 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7420 3.5980 -0.0109 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5373 -1.0085 0.0805 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3116 -2.3318 0.1998 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6771 -0.5891 0.0204 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2338 5.4193 0.0641 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8603 5.9716 -1.0005 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1313 7.0316 -3.1713 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9474 5.7407 -3.0270 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3328 5.2142 -1.9795 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6871 7.8889 -2.2403 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0224 7.3712 -1.1002 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5482 8.2461 -0.1136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7323 9.5911 -0.2618 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3894 10.1049 -1.3893 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8609 9.2731 -2.3660 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2730 10.4418 0.6944 O 0 0 0 0 0 0 0 0 0 0 0 0 4.5590 11.4470 -1.5124 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2357 11.9107 -2.6826 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6118 9.8581 1.8187 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4394 -3.2650 0.2570 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2107 -4.6078 0.9538 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3371 -4.5484 -0.5698 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6310 2.3492 -0.1334 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9783 -0.0577 -0.1460 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9209 -1.6096 -0.0501 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7775 1.1920 0.1419 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1118 3.6055 0.1584 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9071 4.2817 -0.0528 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4023 -2.6664 0.2477 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3174 5.0778 -3.7951 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0405 7.8595 0.7577 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3652 9.6808 -3.2297 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3038 12.9982 -2.6559 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2383 11.4845 -2.7154 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6809 11.6030 -3.5690 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2964 10.6452 2.5036 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7388 9.3015 1.4781 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2960 9.1825 2.3320 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4236 -2.8074 0.3569 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0445 -5.0337 1.5119 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2210 -4.7968 1.3697 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4307 -4.6983 -1.1563 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2542 -4.9352 -1.0141 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 32 1 0 0 0 0 2 3 1 0 0 0 0 2 33 1 0 0 0 0 3 4 2 0 0 0 0 3 34 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 35 1 0 0 0 0 8 9 2 0 0 0 0 8 36 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 37 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 29 1 0 0 0 0 12 38 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 39 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 25 1 0 0 0 0 23 24 2 0 0 0 0 23 26 1 0 0 0 0 24 41 1 0 0 0 0 25 28 1 0 0 0 0 26 27 1 0 0 0 0 27 42 1 0 0 0 0 27 43 1 0 0 0 0 27 44 1 0 0 0 0 28 45 1 0 0 0 0 28 46 1 0 0 0 0 28 47 1 0 0 0 0 29 30 1 0 0 0 0 29 31 1 0 0 0 0 29 48 1 0 0 0 0 30 31 1 0 0 0 0 30 49 1 0 0 0 0 30 50 1 0 0 0 0 31 51 1 0 0 0 0 31 52 1 0 0 0 0 M END > 541165 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 23 > 2008 > 541165 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 23 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 75 80 0 0 0 0 0 0 0 0999 V2000 -0.0240 1.4497 -0.6281 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1869 2.1350 -0.4577 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1987 3.4576 -0.0733 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2181 2.0803 -0.4215 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2337 3.4244 -0.0302 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0134 4.1222 0.1491 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0563 5.4089 0.5289 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2074 6.0051 0.7293 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3711 5.3939 0.5744 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4425 4.1228 0.2016 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3615 1.4876 -0.6736 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5615 2.2398 -0.4830 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0101 0.1443 -1.0086 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.2762 -0.4993 -1.1656 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6636 3.4978 0.0439 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8435 4.2321 0.1637 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8754 5.5642 -0.2382 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0384 6.2934 -0.1275 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.1902 5.6962 0.3888 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.1577 4.3542 0.7931 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9847 3.6299 0.6786 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.4380 6.4753 0.5085 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.5707 7.7133 0.1651 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.9577 5.8482 1.1318 S 0 0 0 0 0 0 0 0 0 0 0 0 -10.7260 7.4115 0.8683 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7757 8.2865 0.3300 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.1736 9.6094 0.0360 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.4506 10.0166 0.2733 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.3868 9.1428 0.8077 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.0289 7.8466 1.1033 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7723 1.3498 -0.7704 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0571 2.1552 -0.5663 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2197 1.3007 -0.8422 N 0 0 0 0 0 0 0 0 0 0 0 0 8.4565 2.0931 -0.8890 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6503 1.1586 -1.0988 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4647 0.4033 -2.3456 N 0 0 0 0 0 0 0 0 0 0 0 0 8.2279 -0.3891 -2.2989 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0341 0.5454 -2.0891 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6273 -0.4512 -2.6215 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.2740 3.7673 1.2960 O 0 0 0 0 0 0 0 0 0 0 0 0 -8.1664 2.3971 1.6873 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1361 3.9781 0.0561 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1457 1.5446 -0.5598 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2055 7.0410 1.0347 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5677 3.0922 -1.1623 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6079 2.5952 0.5463 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1223 -1.5343 -1.4708 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8155 -0.4761 -0.2186 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8567 0.0216 -1.9270 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7009 2.5482 -0.1501 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9854 6.0275 -0.6377 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0595 7.3271 -0.4397 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.9562 2.5958 0.9891 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.4586 10.3038 -0.3801 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.7385 11.0318 0.0431 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.3965 9.4794 0.9912 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.7580 7.1668 1.5189 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7661 0.4974 -0.0911 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7259 0.9944 -1.7998 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0634 3.0076 -1.2456 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1035 2.5106 0.4630 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4019 2.8040 -1.7134 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5780 2.6332 0.0499 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5657 1.7468 -1.1627 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7210 0.4652 -0.2607 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1064 -0.9292 -3.2378 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2825 -1.1000 -1.4744 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1187 -0.0429 -2.0251 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9634 1.2387 -2.9272 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7620 -1.1572 -1.8020 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4636 -0.9989 -3.5496 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5189 0.1683 -2.7176 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.8817 1.7943 0.8250 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.4087 2.2998 2.4648 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.1268 2.0523 2.0706 H 0 0 0 0 0 0 0 0 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 42 1 0 0 0 0 4 5 2 0 0 0 0 4 43 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 44 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 45 1 0 0 0 0 12 46 1 0 0 0 0 13 14 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 14 49 1 0 0 0 0 15 16 1 0 0 0 0 15 50 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 51 1 0 0 0 0 18 19 2 0 0 0 0 18 52 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 40 1 0 0 0 0 21 53 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 54 1 0 0 0 0 28 29 1 0 0 0 0 28 55 1 0 0 0 0 29 30 2 0 0 0 0 29 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 58 1 0 0 0 0 31 59 1 0 0 0 0 32 33 1 0 0 0 0 32 60 1 0 0 0 0 32 61 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 62 1 0 0 0 0 34 63 1 0 0 0 0 35 36 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 38 68 1 0 0 0 0 38 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 39 72 1 0 0 0 0 40 41 1 0 0 0 0 41 73 1 0 0 0 0 41 74 1 0 0 0 0 41 75 1 0 0 0 0 M END > 691744 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 13 > 2009 > 691744 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 13 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 32 35 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8409 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3464 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6788 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6616 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9881 -0.9593 0.0063 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1705 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0934 -1.5676 -0.7688 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6094 -3.2090 0.6661 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0260 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0371 -3.2645 0.3603 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2897 -2.2150 -0.5433 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5819 -2.0174 -1.0193 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6022 -2.8450 -0.6071 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3561 -3.8846 0.2869 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0824 -4.0978 0.7726 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3758 -4.6923 0.6833 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0007 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4433 -3.0500 -0.0020 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0253 -0.6585 0.0179 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9743 -0.8027 -1.3534 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0677 -3.8684 1.3281 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7848 -1.2147 -1.7128 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6031 -2.6869 -0.9809 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8932 -4.9041 1.4657 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8375 -4.3833 1.4748 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 21 1 0 0 0 0 1 22 1 0 0 0 0 2 3 1 0 0 0 0 2 23 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 5 2 0 0 0 0 4 9 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 24 1 0 0 0 0 8 9 2 0 0 0 0 8 25 1 0 0 0 0 9 26 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 27 1 0 0 0 0 12 14 1 0 0 0 0 12 28 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 29 1 0 0 0 0 17 18 1 0 0 0 0 17 30 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 31 1 0 0 0 0 20 32 1 0 0 0 0 M END > 592714 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12h > 2008 > 592714 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12h > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 0.0688 1.3125 0.6478 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2414 2.0582 0.4634 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4107 1.4449 0.0710 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0608 -0.0380 0.4429 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2362 -0.6857 0.0442 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4254 0.0616 -0.1446 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5386 -0.5838 -0.5264 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5220 -1.8811 -0.7200 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4357 -2.6193 -0.5565 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2825 -2.0821 -0.1805 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2243 3.4003 0.6733 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4506 4.1047 0.4683 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1572 -2.8645 -0.0134 N 0 0 0 0 0 0 0 0 0 0 0 0 0.2492 -4.2519 -0.1265 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4107 -4.9052 0.2720 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5026 -6.2755 0.1664 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4279 -7.0090 -0.3408 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7372 -6.3503 -0.7396 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8229 -4.9797 -0.6321 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5234 -8.4790 -0.4558 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4107 -9.2452 -0.9101 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9285 -9.4327 -0.0004 S 0 0 0 0 0 0 0 0 0 0 0 0 1.1009 -10.9091 -0.4892 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1726 -10.5675 -0.9586 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0215 -11.6032 -1.4081 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6058 -12.8988 -1.3825 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6596 -13.2300 -0.9153 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5100 -12.2413 -0.4711 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2371 5.5931 0.7508 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5501 6.3473 0.5314 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3451 7.7765 0.8026 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6263 8.4955 0.8344 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3649 9.9895 1.0397 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6224 10.1866 2.2925 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3412 9.4675 2.2607 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6026 7.9735 2.0554 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4174 11.6157 2.5638 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1694 -14.8893 -0.8909 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -1.0720 1.9397 1.0406 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.2324 1.1248 1.2174 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3095 2.0269 -0.0695 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8478 -0.6035 0.5880 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4355 -2.3686 -1.0269 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2120 3.7124 1.1425 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7767 3.9738 -0.5635 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6974 -2.4495 0.1827 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2415 -4.3375 0.6642 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4050 -6.7822 0.4753 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5701 -6.9149 -1.1320 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7253 -4.4701 -0.9363 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0090 -11.3649 -1.7750 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2676 -13.6787 -1.7293 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4940 -12.4987 -0.1081 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4757 5.9854 0.0766 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9110 5.7240 1.7827 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3115 5.9551 1.2055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8762 6.2165 -0.5005 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2356 8.1168 1.6551 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1516 8.3445 -0.1087 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3150 10.5211 1.0926 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7786 10.3741 0.2052 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8159 9.6185 3.2038 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7319 9.8462 1.4401 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6525 7.4420 2.0025 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1889 7.5889 2.8899 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8502 12.0628 1.7473 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8656 11.7330 3.4964 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3843 12.1117 2.6488 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0699 1.7482 1.5307 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4778 0.6329 0.2762 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0348 0.3717 1.9802 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 39 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 13 46 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 47 1 0 0 0 0 16 17 2 0 0 0 0 16 48 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 49 1 0 0 0 0 19 50 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 51 1 0 0 0 0 26 27 1 0 0 0 0 26 52 1 0 0 0 0 27 28 2 0 0 0 0 27 38 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 62 1 0 0 0 0 35 63 1 0 0 0 0 36 64 1 0 0 0 0 36 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 39 40 1 0 0 0 0 40 69 1 0 0 0 0 40 70 1 0 0 0 0 40 71 1 0 0 0 0 M END > 691755 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 18 > 2009 > 691755 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 18 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 52 55 0 0 0 999 V2000 -0.3960 1.3491 0.1168 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5346 1.9993 1.3514 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5674 1.2896 2.5170 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2910 -0.0104 0.0540 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3163 -0.7641 1.2370 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4618 -0.1108 2.4851 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4863 -0.8276 3.6150 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3782 -2.1354 3.6029 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2326 -2.8475 2.4190 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2102 -2.1729 1.2110 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3715 2.0798 -1.0297 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.6372 3.3538 1.3880 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.7758 3.9593 2.6749 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2340 1.3587 -2.2558 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0694 -2.8415 0.0398 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.0621 -4.1997 0.0775 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1175 -4.8725 -0.0736 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2836 -6.2518 0.3185 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2607 -4.8913 0.2762 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0918 -6.9733 0.1611 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1258 -6.2768 -0.0347 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3214 -7.0007 -0.1872 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3063 -8.3628 -0.1466 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1220 -9.0633 0.0441 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0810 -8.3901 0.1986 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3345 -9.1401 0.4007 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3303 -10.4868 0.3457 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.3718 -8.5437 0.6170 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5756 -11.2319 0.5464 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2961 -12.7320 0.4342 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3657 -13.1072 1.4093 F 0 0 0 0 0 0 0 0 0 0 0 0 -3.4852 -13.4436 0.6259 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.7816 -13.0168 -0.8353 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.6739 1.8033 3.4610 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1804 -0.5026 -0.9009 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4028 -2.6730 4.5393 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1457 -3.9237 2.4408 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8473 5.0410 2.5616 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6782 3.5841 3.1577 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0923 3.7147 3.2870 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2287 2.0593 -3.0908 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7012 0.7989 -2.2452 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0698 0.6678 -2.3666 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0381 -4.3278 -0.2225 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2171 -6.7737 0.4687 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1807 -4.3388 0.3981 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2535 -6.4762 -0.3373 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2314 -8.9073 -0.2650 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1380 -10.1428 0.0720 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5028 -10.9626 0.1732 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9764 -11.0100 1.5355 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3004 -10.9396 -0.2133 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 34 1 0 0 0 0 4 5 2 0 0 0 0 4 35 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 36 1 0 0 0 0 9 10 2 0 0 0 0 9 37 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 13 40 1 0 0 0 0 14 41 1 0 0 0 0 14 42 1 0 0 0 0 14 43 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 44 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 45 1 0 0 0 0 19 46 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 47 1 0 0 0 0 23 24 2 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 50 1 0 0 0 0 29 30 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 30 32 1 0 0 0 0 30 33 1 0 0 0 0 M END > 540562 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 19 > 2008 > 540562 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 19 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 53 57 0 0 0 999 V2000 0.7100 1.0356 -0.2946 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8467 -0.3121 -0.1492 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0628 -0.8763 0.2163 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1734 -0.0774 0.4429 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8096 1.8845 -0.0750 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0577 1.3283 0.2978 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1550 2.1720 0.5166 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0162 3.5184 0.3699 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7890 4.0771 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6913 3.2766 -0.2197 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4606 -0.6833 0.8311 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5405 -2.0097 1.0561 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4500 0.0139 0.9481 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6780 5.4242 -0.1370 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2142 5.9960 -1.2423 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3048 7.1424 -3.5147 N 0 0 0 0 0 0 0 0 0 0 0 0 4.2957 5.8367 -3.3763 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7588 5.2223 -2.2533 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7971 7.9521 -2.5790 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2297 7.4016 -1.4016 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6972 8.2463 -0.4221 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7299 9.6195 -0.6135 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2956 10.1606 -1.7877 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8172 9.3465 -2.7495 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3204 11.5059 -1.9619 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9063 11.9928 -3.1710 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8193 -2.6116 1.4417 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7742 -3.9217 2.2306 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2140 -3.9259 0.7652 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1707 10.5179 0.4139 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1981 11.7223 0.2485 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6293 10.0039 1.5361 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.2435 1.4526 -0.5835 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0053 -0.9532 -0.3207 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1437 -1.9477 0.3254 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1094 1.7546 0.8017 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8656 4.1633 0.5404 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7464 3.7156 -0.5040 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7513 -2.5659 0.9627 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7174 5.2232 -4.1588 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7660 4.1457 -2.1684 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2636 7.8323 0.4762 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2467 9.7743 -3.6433 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8617 13.0819 -3.1834 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9462 11.6711 -3.2260 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3577 11.5969 -4.0256 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6173 -1.9081 1.6795 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5426 -4.0803 2.9872 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7930 -4.3358 2.4628 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5222 -4.3429 0.0333 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2718 -4.0874 0.5578 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6075 9.0432 1.6680 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2616 10.5948 2.2118 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 33 1 0 0 0 0 2 3 1 0 0 0 0 2 34 1 0 0 0 0 3 4 2 0 0 0 0 3 35 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 36 1 0 0 0 0 8 9 2 0 0 0 0 8 37 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 38 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 27 1 0 0 0 0 12 39 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 30 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 24 43 1 0 0 0 0 25 26 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 27 28 1 0 0 0 0 27 29 1 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 2 0 0 0 0 30 32 1 0 0 0 0 32 52 1 0 0 0 0 32 53 1 0 0 0 0 M END > 541095 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 29 > 2008 > 541095 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 29 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 59 64 0 0 0 0 0 0 0 0999 V2000 -1.0625 -0.6874 2.4231 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3338 -0.9688 3.5666 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8972 -1.5878 3.4525 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3892 -1.9149 2.2731 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7329 -1.6679 1.1520 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5204 -1.0434 1.1862 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2768 -2.0210 -0.0381 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5382 -2.5270 -0.0381 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5904 -1.7429 -0.4175 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8906 -2.2393 -0.4199 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1512 -3.5375 -0.0389 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7645 -3.8606 0.3588 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0853 -4.3727 0.3588 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3095 -5.7008 0.7532 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2572 -6.4787 1.1306 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9583 -5.9754 1.1313 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7047 -4.6903 0.7593 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2579 -0.7648 -0.0681 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5087 -0.1414 -0.0325 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1571 0.1033 -1.2295 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5792 -0.2569 -2.3647 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.3922 -0.8466 -2.3692 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7372 -1.0995 -1.2473 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4613 -4.0239 -0.0468 N 0 0 0 0 0 0 0 0 0 0 0 0 7.5133 -3.1683 -0.3020 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8193 -3.5469 -0.4309 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4077 -1.8725 -0.4622 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6355 -1.3403 -0.6973 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5561 -2.4011 -0.6809 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9031 -2.1522 -0.8968 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3352 -0.8618 -1.1236 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4309 0.1899 -1.1372 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0889 -0.0398 -0.9330 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8230 -1.2073 -3.5782 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.5318 -0.9362 -4.8313 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9200 1.5935 -1.3859 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3064 1.5781 -1.5724 F 0 0 0 0 0 0 0 0 0 0 0 0 10.3011 2.1069 -2.5307 F 0 0 0 0 0 0 0 0 0 0 0 0 10.6064 2.3985 -0.2855 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.0284 -0.2084 2.4866 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7235 -0.7066 4.5391 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4658 -1.8071 4.3441 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4105 -0.7220 -0.7205 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7053 -1.5992 -0.7245 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3114 -6.1041 0.7570 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4323 -7.5006 1.4333 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1409 -6.6128 1.4347 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6926 -4.3135 0.7646 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9583 0.1421 0.9076 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1247 0.5829 -1.2379 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6311 -4.9629 0.1272 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1661 -4.4500 -0.3603 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6123 -2.9666 -0.8872 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3846 -0.6692 -1.2913 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3902 0.7837 -0.9449 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0452 -1.6395 -3.5957 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4902 -1.4552 -4.8263 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6999 0.1364 -4.9290 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9325 -1.2879 -5.6711 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 40 1 0 0 0 0 2 3 1 0 0 0 0 2 41 1 0 0 0 0 3 4 2 0 0 0 0 3 42 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 12 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 43 1 0 0 0 0 10 11 2 0 0 0 0 10 44 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 13 1 0 0 0 0 12 17 2 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 45 1 0 0 0 0 15 16 2 0 0 0 0 15 46 1 0 0 0 0 16 17 1 0 0 0 0 16 47 1 0 0 0 0 17 48 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 49 1 0 0 0 0 20 21 2 0 0 0 0 20 50 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 51 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 26 52 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 53 1 0 0 0 0 31 32 1 0 0 0 0 31 54 1 0 0 0 0 32 33 2 0 0 0 0 32 36 1 0 0 0 0 33 55 1 0 0 0 0 34 35 1 0 0 0 0 34 56 1 0 0 0 0 35 57 1 0 0 0 0 35 58 1 0 0 0 0 35 59 1 0 0 0 0 36 37 1 0 0 0 0 36 38 1 0 0 0 0 36 39 1 0 0 0 0 M END > 596068 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 10 > 2010 > 596068 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 10 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 76 81 0 0 0 0 0 0 0 0999 V2000 -3.0532 2.8406 -2.1675 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0767 3.8125 -2.3071 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7638 3.5052 -2.0013 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4257 2.3021 -1.5789 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.3201 1.3399 -1.4291 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6703 1.5746 -1.7187 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9278 0.1182 -0.9928 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4019 -0.0986 -0.8135 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1412 -0.6768 -1.8060 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5050 -0.9032 -1.6454 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1466 -0.5492 -0.4786 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0225 0.2780 0.3949 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4103 0.0506 0.5655 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0272 0.4249 1.7692 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2859 1.0011 2.7558 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9213 1.2254 2.5884 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2911 0.8792 1.4319 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6749 0.4987 -1.5514 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0213 0.7326 -1.8463 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9219 -0.3039 -1.6802 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.4863 -1.4777 -1.2502 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.2038 -1.6718 -0.9780 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3086 -0.7079 -1.1229 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5164 -0.7829 -0.3298 N 0 0 0 0 0 0 0 0 0 0 0 0 5.2039 -1.4920 -1.2933 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5463 -1.7433 -1.2743 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6656 -2.0293 -2.3598 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6265 -2.6515 -3.0916 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8425 -2.4786 -2.4101 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0101 -3.0165 -2.9299 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9740 -3.7173 -4.1177 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7766 -3.8879 -4.7967 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6063 -3.3679 -4.2911 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7900 -2.9146 -0.5307 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.7652 -3.9949 -0.3636 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0524 -5.2524 0.1380 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0709 -6.3807 0.3125 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9906 -5.6765 -0.8787 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3828 -4.9574 1.4817 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.8393 -6.5431 -0.9290 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.1270 -7.4072 -1.8797 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.1848 -7.0630 -0.6511 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0863 3.0575 -2.3958 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3383 4.8019 -2.6521 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0020 4.2630 -2.1104 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6599 -0.9631 -2.7295 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0672 -1.3622 -2.4451 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0843 0.2565 1.9126 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7628 1.2879 3.6814 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3556 1.6836 3.3861 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7674 1.0590 1.3159 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3505 1.7002 -2.1954 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.9693 -0.1571 -1.8986 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9838 -0.4465 0.4508 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1752 -1.4595 -0.5925 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9457 -2.8869 -2.4062 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8841 -4.1355 -4.5217 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7611 -4.4382 -5.7259 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6775 -3.5045 -4.8250 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8543 -3.0702 -0.3278 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5216 -3.6928 0.3608 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2423 -4.2051 -1.3208 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5484 -7.3098 0.5405 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7488 -6.1350 1.1299 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1220 -5.0239 -0.7907 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6922 -6.7067 -0.6842 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4011 -5.6011 -1.8857 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1459 -4.7263 2.2249 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8145 -5.8300 1.8037 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7110 -4.1059 1.3737 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.8478 -8.3380 -1.3860 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.7756 -7.6262 -2.7280 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2291 -6.8985 -2.2307 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.7154 -6.3684 0.0001 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.7321 -7.1737 -1.5872 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.1053 -8.0328 -0.1599 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 43 1 0 0 0 0 2 3 1 0 0 0 0 2 44 1 0 0 0 0 3 4 2 0 0 0 0 3 45 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 12 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 46 1 0 0 0 0 10 11 2 0 0 0 0 10 47 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 13 1 0 0 0 0 12 17 2 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 48 1 0 0 0 0 15 16 2 0 0 0 0 15 49 1 0 0 0 0 16 17 1 0 0 0 0 16 50 1 0 0 0 0 17 51 1 0 0 0 0 18 23 1 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 19 52 1 0 0 0 0 20 21 2 0 0 0 0 20 53 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 54 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 26 55 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 32 33 2 0 0 0 0 32 58 1 0 0 0 0 33 59 1 0 0 0 0 34 35 1 0 0 0 0 34 60 1 0 0 0 0 35 36 1 0 0 0 0 35 61 1 0 0 0 0 35 62 1 0 0 0 0 36 37 1 0 0 0 0 36 38 1 0 0 0 0 36 39 1 0 0 0 0 37 40 1 0 0 0 0 37 63 1 0 0 0 0 37 64 1 0 0 0 0 38 65 1 0 0 0 0 38 66 1 0 0 0 0 38 67 1 0 0 0 0 39 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 40 41 1 0 0 0 0 40 42 1 0 0 0 0 41 71 1 0 0 0 0 41 72 1 0 0 0 0 41 73 1 0 0 0 0 42 74 1 0 0 0 0 42 75 1 0 0 0 0 42 76 1 0 0 0 0 M END > 731888 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 4 > 2010 > 731888 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 4 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 70 75 0 0 0 0 0 0 0 0999 V2000 0.0764 1.3212 0.5902 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2318 2.0717 0.3292 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3821 1.4602 -0.1171 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0668 -0.0321 0.4074 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2237 -0.6789 -0.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3954 0.0735 -0.3116 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4902 -0.5703 -0.7442 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4714 -1.8704 -0.9163 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4000 -2.6119 -0.6812 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2676 -2.0763 -0.2510 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2160 3.4168 0.5183 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4237 4.1260 0.2347 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1808 -2.8471 -0.0145 O 0 0 0 0 0 0 0 0 0 0 0 0 0.3174 -4.1937 -0.1275 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1767 -4.8485 -1.2487 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0349 -6.2138 -1.3696 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6062 -6.9392 -0.3635 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1014 -6.2775 0.7619 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9558 -4.9119 0.8756 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7598 -8.4036 -0.4891 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3348 -9.1621 0.3827 N 0 0 0 0 0 0 0 0 0 0 0 0 0.1786 -9.3619 -1.8438 S 0 0 0 0 0 0 0 0 0 0 0 0 0.7956 -10.8286 -1.0877 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3928 -10.4809 0.1294 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9611 -11.5086 0.9146 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9252 -12.8019 0.4920 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3314 -13.1382 -0.7165 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7684 -12.1587 -1.5031 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2148 5.6174 0.5047 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5079 6.3768 0.2010 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3073 7.8087 0.4602 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5828 8.5368 0.4097 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3216 10.0322 0.6052 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6479 10.2448 1.8937 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3723 9.5167 1.9443 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6335 8.0213 1.7488 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4472 11.6767 2.1530 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0454 1.9473 1.0357 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.1883 1.1278 1.2894 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2674 2.0459 -0.3160 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8282 -0.6010 0.6117 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3697 -2.3577 -1.2657 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2241 3.7500 0.8720 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6935 3.9804 -0.8114 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6728 -4.2868 -2.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4196 -6.7223 -2.2414 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5976 -6.8352 1.5423 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3389 -4.3993 1.7456 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4281 -11.2660 1.8576 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3643 -13.5756 1.1043 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3104 -14.1685 -1.0396 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3062 -12.4210 -2.4433 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4144 5.9934 -0.1327 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9451 5.7630 1.5507 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3082 6.0008 0.8383 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7776 6.2312 -0.8451 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2392 8.1758 1.2014 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0564 8.3739 -0.5584 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2692 10.5709 0.5970 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6874 10.3991 -0.2018 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8987 9.6796 2.9124 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7159 9.8777 1.1525 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6860 7.4826 1.7569 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2678 7.6544 2.5557 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8326 12.1065 1.3621 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9468 11.8056 3.1127 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4135 12.1806 2.1765 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9432 0.3884 2.0518 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0117 1.7508 1.6388 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4818 0.6192 0.3710 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 38 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 40 1 0 0 0 0 4 5 2 0 0 0 0 4 41 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 42 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 43 1 0 0 0 0 12 44 1 0 0 0 0 13 14 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 45 1 0 0 0 0 16 17 2 0 0 0 0 16 46 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 47 1 0 0 0 0 19 48 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 49 1 0 0 0 0 26 27 1 0 0 0 0 26 50 1 0 0 0 0 27 28 2 0 0 0 0 27 51 1 0 0 0 0 28 52 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 57 1 0 0 0 0 32 58 1 0 0 0 0 33 34 1 0 0 0 0 33 59 1 0 0 0 0 33 60 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 61 1 0 0 0 0 35 62 1 0 0 0 0 36 63 1 0 0 0 0 36 64 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 38 39 1 0 0 0 0 39 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 M END > 691668 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 24 > 2009 > 691668 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 24 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 39 42 0 0 0 999 V2000 -0.0165 1.3634 0.0095 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2579 1.7989 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1264 0.7032 -0.0145 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4128 -0.4041 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9344 -1.7858 -0.0267 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6891 -3.0042 0.0427 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4550 -3.4699 0.0281 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4093 -2.6695 0.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5770 -1.2825 0.0301 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8770 -0.7586 0.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9400 -1.6435 0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4074 -0.3858 0.0233 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1670 -0.9003 0.0088 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2614 -2.1275 -0.0416 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1978 -2.8701 -0.0203 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9979 -3.9648 -0.0355 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3276 -3.5074 -0.0494 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3726 -4.4202 -0.0645 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0976 -5.7761 -0.0689 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7803 -6.2267 -0.0583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7422 -5.3401 -0.0368 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1190 -6.6731 -0.0840 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7662 -8.0579 -0.0878 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8991 1.9855 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5312 2.7296 0.0018 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5178 -3.6968 0.0431 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4140 -3.0886 0.0095 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0442 0.3084 0.0531 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.9555 -1.2761 0.0637 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5478 0.6850 0.0301 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0266 -1.9711 0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0136 -1.5150 -0.0460 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3956 -4.0739 -0.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5777 -7.2876 -0.0622 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7241 -5.7004 -0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1877 -8.2879 0.8069 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1696 -8.2785 -0.9729 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6724 -8.6636 -0.1003 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 2 0 0 0 0 1 2 1 0 0 0 0 1 25 1 0 0 0 0 2 3 1 0 0 0 0 2 26 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 14 1 0 0 0 0 6 15 1 0 0 0 0 6 16 2 0 0 0 0 7 12 1 0 0 0 0 7 8 2 0 0 0 0 7 27 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 28 1 0 0 0 0 10 13 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 29 1 0 0 0 0 12 30 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 32 1 0 0 0 0 15 18 1 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 34 1 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 35 1 0 0 0 0 22 36 1 0 0 0 0 23 24 1 0 0 0 0 24 37 1 0 0 0 0 24 38 1 0 0 0 0 24 39 1 0 0 0 0 M END > 510936 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2a > 2007 > 510936 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17574416 > Bioorg. Med. Chem. Lett.|2007|17|16|4557 > 2a > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 46 49 0 0 0 999 V2000 0.0900 1.2818 -0.5498 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0919 -0.1010 -0.3179 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2280 -0.7423 0.0841 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2267 2.0179 -0.3787 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4086 1.3843 0.0334 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4137 -0.0122 0.2688 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5398 -0.6188 0.6627 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6554 0.0490 0.8402 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7297 1.4202 0.6301 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6044 2.1135 0.2205 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0543 1.8948 -0.9547 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.0524 -0.8122 -0.4951 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9885 -2.2174 -0.2433 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9918 3.3054 -1.1743 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6473 3.4519 0.0072 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8516 4.0743 0.0999 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1361 4.8329 1.2000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0008 4.5376 -0.8633 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7863 3.9259 -0.9291 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3227 5.3281 0.2489 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3811 5.4767 1.2965 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7065 6.2652 2.4141 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9200 6.8811 2.4867 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8562 6.7475 1.4692 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5775 5.9797 0.3480 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5760 5.8421 -0.7284 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7308 6.5346 -0.6689 N 0 0 0 0 0 0 0 0 0 0 0 0 9.3575 5.1040 -1.6697 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2151 -1.8079 0.2598 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2164 3.0825 -0.5602 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5402 -0.4820 1.1589 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6620 1.9429 0.7851 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2548 -2.6727 -0.9085 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6951 -2.3880 0.7925 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9670 -2.6633 -0.4219 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9694 3.6672 -1.4931 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7036 3.8048 -0.2493 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2548 3.5204 -1.9481 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4080 4.9373 1.9908 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7121 4.4178 -1.6671 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5419 3.3176 -1.7873 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9933 6.3833 3.2164 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1580 7.4841 3.3505 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8104 7.2466 1.5517 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9051 7.1234 0.0820 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3876 6.4441 -1.3770 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 29 1 0 0 0 0 4 5 2 0 0 0 0 4 30 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 31 1 0 0 0 0 9 10 2 0 0 0 0 9 32 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 33 1 0 0 0 0 13 34 1 0 0 0 0 13 35 1 0 0 0 0 14 36 1 0 0 0 0 14 37 1 0 0 0 0 14 38 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 39 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 40 1 0 0 0 0 19 41 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 42 1 0 0 0 0 23 24 2 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 M END > 541171 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 22 > 2008 > 541171 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 22 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 52 55 0 0 0 999 V2000 0.7107 1.0374 -0.2942 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8457 -0.3105 -0.1487 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0610 -0.8761 0.2173 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1723 -0.0786 0.4446 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8112 1.8849 -0.0743 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0584 1.3273 0.2993 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1564 2.1697 0.5194 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0192 3.5163 0.3729 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7928 4.0765 0.0045 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6947 3.2772 -0.2191 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4587 -0.6859 0.8336 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5368 -2.0125 1.0587 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4488 0.0101 0.9514 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6832 5.4238 -0.1338 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2210 5.9959 -1.2388 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3238 7.1421 -3.5048 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3088 5.8364 -3.3701 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7653 5.2223 -2.2495 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8107 7.9498 -2.5697 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2379 7.3999 -1.3970 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6998 8.2488 -0.4180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7306 9.5968 -0.5996 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2937 10.1505 -1.7535 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8292 9.3447 -2.7321 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3121 11.4996 -1.9105 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7408 12.2828 -0.8606 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8147 -2.6158 1.4452 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6297 -4.1222 1.6382 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2902 -4.7246 0.3876 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0944 -6.1384 0.4576 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2422 1.4554 -0.5834 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0071 -0.9506 -0.3204 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1407 -1.9477 0.3261 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1102 1.7513 0.8051 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8692 4.1602 0.5439 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7505 3.7173 -0.5041 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7470 -2.5677 0.9648 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7342 5.2230 -4.1506 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7676 4.1455 -2.1667 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2617 7.8331 0.4774 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3150 10.2467 0.1562 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2618 9.7824 -3.6196 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2753 12.0889 0.0694 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8204 13.3405 -1.1117 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6909 12.0164 -0.7386 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5521 -2.4376 0.6626 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1598 -2.1696 2.3779 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5569 -4.5573 2.0112 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8297 -4.3010 2.3567 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0105 -6.6152 0.8060 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2833 -6.3589 1.1515 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8400 -6.5193 -0.5315 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 5 1 0 0 0 0 1 31 1 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 4 2 0 0 0 0 3 33 1 0 0 0 0 4 6 1 0 0 0 0 4 11 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 34 1 0 0 0 0 8 9 2 0 0 0 0 8 35 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 36 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 27 1 0 0 0 0 12 37 1 0 0 0 0 14 15 1 0 0 0 0 15 20 2 0 0 0 0 15 18 1 0 0 0 0 16 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 41 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 24 42 1 0 0 0 0 25 26 1 0 0 0 0 26 43 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 27 28 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 30 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 M END > 541096 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 27 > 2008 > 541096 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 27 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 56 60 0 0 0 999 V2000 1.4277 3.1788 1.4590 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7758 2.0645 0.6378 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3925 3.5243 0.3867 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2232 -1.4328 1.0064 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0515 -1.9700 0.0169 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7627 -1.7862 -1.3164 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1128 -0.7177 0.6756 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7897 -0.5123 -0.6724 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6229 -1.0515 -1.6827 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2968 -0.8435 -3.0348 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1864 -0.1279 -3.3682 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3568 0.4090 -2.3914 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6399 0.2287 -1.0459 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7545 0.8011 -0.0147 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6006 1.3982 -0.3731 N 0 0 0 0 0 0 0 0 0 0 0 0 3.0655 0.7343 1.1589 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1535 -2.6796 0.3747 O 0 0 0 0 0 0 0 0 0 0 0 0 7.9812 -3.9628 0.7777 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6059 -6.5807 1.5962 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5755 -5.8498 1.2397 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7208 -4.5330 0.8231 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8526 -6.0953 1.5716 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0831 -4.7605 1.1583 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3918 -4.2542 1.1328 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4325 -5.0536 1.5071 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2074 -6.3760 1.9169 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9451 -6.8936 1.9505 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2602 -7.1523 2.2848 O 0 0 0 0 0 0 0 0 0 0 0 0 11.9684 -8.4904 2.6926 C 0 0 0 0 0 0 0 0 0 0 0 0 12.7006 -4.5633 1.4820 O 0 0 0 0 0 0 0 0 0 0 0 0 12.8644 -3.2096 1.0548 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2505 1.1754 1.3428 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1252 3.2786 2.5014 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4703 3.4161 1.2471 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5911 3.8514 0.7236 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7540 3.9889 -0.5307 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4644 -1.5915 2.0471 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4080 -2.2034 -2.0753 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4821 -0.3090 1.4512 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9279 -1.2516 -3.8104 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9468 0.0248 -4.4102 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4829 0.9726 -2.6829 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3162 1.3867 -1.3004 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5869 -6.2832 1.2754 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8540 -3.9563 0.5362 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5743 -3.2373 0.8183 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7862 -7.9135 2.2682 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8948 -8.9992 2.9592 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3035 -8.4702 3.5561 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4844 -9.0224 1.8736 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9216 -2.9456 1.0815 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4885 -3.1016 0.0374 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3081 -2.5489 1.7197 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2668 0.3901 1.8941 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8388 1.7779 2.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9106 0.7246 0.6018 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1 0 0 0 0 1 2 1 0 0 0 0 1 33 1 0 0 0 0 1 34 1 0 0 0 0 2 15 1 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 35 1 0 0 0 0 3 36 1 0 0 0 0 4 7 1 0 0 0 0 4 5 2 0 0 0 0 4 37 1 0 0 0 0 5 17 1 0 0 0 0 5 6 1 0 0 0 0 6 9 2 0 0 0 0 6 38 1 0 0 0 0 7 8 2 0 0 0 0 7 39 1 0 0 0 0 8 9 1 0 0 0 0 8 13 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 12 1 0 0 0 0 11 41 1 0 0 0 0 12 13 2 0 0 0 0 12 42 1 0 0 0 0 13 14 1 0 0 0 0 14 16 2 0 0 0 0 14 15 1 0 0 0 0 15 43 1 0 0 0 0 17 18 1 0 0 0 0 18 23 2 0 0 0 0 18 21 1 0 0 0 0 19 22 2 0 0 0 0 19 20 1 0 0 0 0 20 21 2 0 0 0 0 20 44 1 0 0 0 0 21 45 1 0 0 0 0 22 23 1 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 46 1 0 0 0 0 25 26 1 0 0 0 0 25 30 1 0 0 0 0 26 27 2 0 0 0 0 26 28 1 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 31 1 0 0 0 0 31 51 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 M END > 540567 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 12 > 2008 > 540567 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 12 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 72 77 0 0 0 0 0 0 0 0999 V2000 -0.0973 1.3159 -0.6271 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2898 2.0283 -0.4389 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4440 1.3800 -0.0584 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0545 -0.0362 -0.4376 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2125 -0.7183 -0.0455 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4230 -0.0057 0.1413 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5215 -0.6852 0.5064 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4712 -1.9836 0.6858 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3640 -2.6903 0.5230 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2227 -2.1179 0.1634 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3073 3.3727 -0.6334 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5525 4.0422 -0.4253 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0281 1.9774 -1.0080 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2103 1.1954 -1.1893 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0753 -2.8677 -0.0031 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1306 -4.2582 0.0937 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9550 -4.9616 0.6072 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9051 -6.3339 0.7104 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2376 -7.0236 0.2995 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3311 -6.3145 -0.2173 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2714 -4.9362 -0.3175 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2940 -8.4944 0.4090 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6571 -9.2369 0.8699 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.6682 -9.4846 -0.0622 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.8052 -10.9396 0.4297 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4542 -10.5654 0.9118 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3264 -11.5795 1.3654 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9455 -12.8858 1.3312 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3050 -13.2486 0.8512 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1775 -12.2822 0.4034 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3772 5.5389 -0.6899 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7104 6.2557 -0.4672 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5422 7.6928 -0.7212 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8418 8.3782 -0.7500 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6190 9.8808 -0.9371 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8772 10.1118 -2.1845 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5776 9.4264 -2.1557 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8004 7.9238 -1.9686 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7089 11.5489 -2.4385 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4451 -6.9788 -0.6185 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.3584 1.9364 0.0851 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8682 -0.5765 -0.5899 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3736 -2.4990 0.9798 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3007 3.6379 -1.1071 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8789 3.8909 0.6036 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4650 0.6993 -0.2528 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0354 0.4462 -1.9615 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0322 1.8442 -1.4920 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7693 -2.4276 -0.1874 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8394 -4.4296 0.9254 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7495 -6.8767 1.1087 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1120 -4.3869 -0.7152 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3037 -11.3162 1.7422 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6246 -13.6490 1.6816 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5940 -14.2890 0.8294 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1507 -12.5650 0.0302 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6290 5.9432 -0.0081 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0508 5.6902 -1.7188 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4587 5.8514 -1.1489 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0369 6.1044 0.5617 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4377 7.9932 -1.5774 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3664 8.2026 0.1892 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5826 10.3878 -0.9877 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0462 10.2711 -0.0958 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0529 9.6021 -3.0948 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9816 9.8115 -1.3282 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8368 7.4168 -1.9179 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3732 7.5336 -2.8099 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1568 12.0013 -1.6147 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1569 11.6915 -3.3675 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6882 12.0203 -2.5218 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1046 -7.0978 0.0786 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 15 16 1 0 0 0 0 15 49 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 51 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 40 1 0 0 0 0 21 52 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 40 72 1 0 0 0 0 M END > 691743 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 12 > 2009 > 691743 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 12 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 74 78 0 0 0 0 0 0 0 0999 V2000 0.5794 3.1117 0.0881 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6465 4.0175 0.1661 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4141 5.3720 0.2584 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7132 3.5534 0.0960 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9765 4.9252 0.1886 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0969 5.8465 0.2738 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1830 7.1559 0.3670 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.4275 7.5706 0.3787 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4611 6.7476 0.3019 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.2965 5.4348 0.2062 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3846 4.5877 0.1264 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8341 1.7790 -0.0019 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.2951 0.9065 -0.0784 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9235 3.5543 0.1509 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9673 4.5268 0.2337 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3248 3.8217 0.2026 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4424 4.8629 0.2912 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7458 4.1859 0.2613 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9705 3.5339 -1.0351 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2657 2.7205 -0.9808 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4342 3.6522 -0.6476 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1528 4.3551 0.6833 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8319 5.1211 0.5808 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6715 5.1073 0.1457 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.1041 4.1787 0.0545 S 0 0 0 0 0 0 0 0 0 0 0 0 -7.0741 5.6461 0.1507 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.2436 6.6862 0.2413 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9624 6.3674 0.2412 N 0 0 0 0 0 0 0 0 0 0 0 0 -8.5795 5.7146 0.1331 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7226 2.8352 -0.5319 C 0 0 0 0 0 0 0 0 0 0 0 0 12.8300 3.7170 -0.3366 O 0 0 0 0 0 0 0 0 0 0 0 0 -9.0598 5.8438 -1.2895 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.3797 5.9224 -1.5505 N 0 0 0 0 0 0 0 0 0 0 0 0 -8.2587 5.8770 -2.1995 O 0 0 0 0 0 0 0 0 0 0 0 0 -10.8222 6.1402 -2.8600 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.1351 5.5801 -3.9282 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.5757 5.7971 -5.2216 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.7005 6.5721 -5.4496 C 0 0 0 0 0 0 0 0 0 0 0 0 -12.3852 7.1308 -4.3862 C 0 0 0 0 0 0 0 0 0 0 0 0 -11.9530 6.9126 -3.0929 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.9081 5.2532 -6.2626 F 0 0 0 0 0 0 0 0 0 0 0 0 2.2419 6.0630 0.3188 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5281 2.8477 0.0303 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6171 8.6311 0.4548 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2494 3.6297 0.0568 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0476 -0.1260 -0.1462 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9090 1.0277 0.8141 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8850 1.1523 -0.9614 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8940 5.2114 -0.6113 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8697 5.0862 1.1641 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3981 3.1371 1.0476 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4224 3.2623 -0.7278 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3691 5.5475 -0.5538 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3448 5.4223 1.2216 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1344 2.8711 -1.2581 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0503 4.2923 -1.8140 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1814 1.9530 -0.2114 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4403 2.2493 -1.9481 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5432 4.3963 -1.4366 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0825 3.6133 1.4789 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9613 5.0517 0.9050 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9077 5.8720 -0.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6215 5.6111 1.5314 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5913 7.7062 0.3130 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.9897 4.8061 0.5740 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.9106 6.5792 0.7083 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6463 2.1545 0.3160 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8722 2.2612 -1.4464 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6818 3.2667 -0.2547 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.0230 5.8281 -0.8306 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.2578 4.9761 -3.7499 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.0433 6.7407 -6.4598 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.2619 7.7351 -4.5670 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.4891 7.3493 -2.2632 H 0 0 0 0 0 0 0 0 0 0 0 0 1 12 1 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 14 1 0 0 0 0 3 6 2 0 0 0 0 3 42 1 0 0 0 0 4 5 2 0 0 0 0 4 43 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 44 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 11 24 1 0 0 0 0 11 45 1 0 0 0 0 12 13 1 0 0 0 0 13 46 1 0 0 0 0 13 47 1 0 0 0 0 13 48 1 0 0 0 0 14 15 1 0 0 0 0 15 16 1 0 0 0 0 15 49 1 0 0 0 0 15 50 1 0 0 0 0 16 17 1 0 0 0 0 16 51 1 0 0 0 0 16 52 1 0 0 0 0 17 18 1 0 0 0 0 17 53 1 0 0 0 0 17 54 1 0 0 0 0 18 23 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 55 1 0 0 0 0 19 56 1 0 0 0 0 20 21 1 0 0 0 0 20 57 1 0 0 0 0 20 58 1 0 0 0 0 21 22 1 0 0 0 0 21 30 1 0 0 0 0 21 59 1 0 0 0 0 22 23 1 0 0 0 0 22 60 1 0 0 0 0 22 61 1 0 0 0 0 23 62 1 0 0 0 0 23 63 1 0 0 0 0 24 25 1 0 0 0 0 24 28 2 0 0 0 0 25 26 1 0 0 0 0 26 27 2 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 27 64 1 0 0 0 0 29 32 1 0 0 0 0 29 65 1 0 0 0 0 29 66 1 0 0 0 0 30 31 1 0 0 0 0 30 67 1 0 0 0 0 30 68 1 0 0 0 0 31 69 1 0 0 0 0 32 33 1 0 0 0 0 32 34 2 0 0 0 0 33 35 1 0 0 0 0 33 70 1 0 0 0 0 35 36 2 0 0 0 0 35 40 1 0 0 0 0 36 37 1 0 0 0 0 36 71 1 0 0 0 0 37 38 2 0 0 0 0 37 41 1 0 0 0 0 38 39 1 0 0 0 0 38 72 1 0 0 0 0 39 40 2 0 0 0 0 39 73 1 0 0 0 0 40 74 1 0 0 0 0 M END > 438094 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 16451062 > J. Med. Chem.|2006|49|3|955 > 46 > 2006 > 438094 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 16451062 > J. Med. Chem.|2006|49|3|955 > 46 > 2006 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 56 60 0 0 0 999 V2000 0.4317 1.0093 -0.4345 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7477 -6.6803 -0.1044 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.3950 -6.8292 -1.3393 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7786 -6.4653 -2.5017 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.4840 -6.1684 -0.0382 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.8269 -5.7867 -1.2174 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.4784 -5.9349 -2.4661 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.8537 -5.5714 -3.5925 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.6390 -5.0749 -3.5764 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.9355 -4.8983 -2.3915 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.5190 -5.2527 -1.1879 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.3865 -7.0459 1.0389 O 0 0 0 0 0 0 0 0 0 0 0 0 -11.6530 -7.3413 -1.3794 O 0 0 0 0 0 0 0 0 0 0 0 0 -12.2608 -7.4691 -2.6663 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.6740 -6.8697 2.2650 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.8561 -5.0920 -0.0160 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.6477 -4.4715 -0.0465 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5062 -5.2107 0.0859 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3909 -2.4370 -0.2532 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5875 -3.0855 -0.2187 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2006 -3.1647 -0.1144 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2564 -4.5698 0.0545 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0622 -5.2997 0.1882 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1393 -4.6574 0.1552 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2141 -3.2803 -0.0105 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9386 -2.5205 -0.1459 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8517 -1.0588 -0.3210 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3455 -0.4428 -0.2605 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.8603 -0.4093 -0.5201 O 0 0 0 0 0 0 0 0 0 0 0 0 1.8923 1.4506 -0.3213 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2083 2.9231 -0.5913 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2621 2.3787 0.8376 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0451 1.2811 -1.4167 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1580 1.5034 0.3376 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.2891 -6.5851 -3.4459 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.9927 -6.0575 0.9172 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1737 -4.7951 -4.5099 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9368 -4.4878 -2.4099 H 0 0 0 0 0 0 0 0 0 0 0 0 -13.2604 -7.8894 -2.5560 H 0 0 0 0 0 0 0 0 0 0 0 0 -12.3292 -6.4873 -3.1349 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.6564 -8.1279 -3.2898 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.7574 -7.4590 2.2404 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.4254 -5.8162 2.3925 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.2959 -7.1996 3.0972 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.5645 -6.2814 0.2143 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3589 -1.3653 -0.3827 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5024 -2.5217 -0.3261 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0972 -6.3713 0.3177 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0495 -5.2294 0.2591 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1793 -2.7961 -0.0328 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1500 -0.9609 -0.1016 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6319 0.7122 -0.6308 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1560 3.1534 -1.0781 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3757 3.5774 -0.8496 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4648 2.6748 1.5193 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2451 2.2508 1.2908 H 0 0 0 0 0 0 0 0 0 0 0 0 1 28 1 0 0 0 0 1 30 1 0 0 0 0 1 33 1 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 5 1 0 0 0 0 2 12 1 0 0 0 0 3 4 1 0 0 0 0 3 13 1 0 0 0 0 4 7 2 0 0 0 0 4 35 1 0 0 0 0 5 6 2 0 0 0 0 5 36 1 0 0 0 0 6 11 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 37 1 0 0 0 0 10 11 2 0 0 0 0 10 38 1 0 0 0 0 11 16 1 0 0 0 0 12 15 1 0 0 0 0 13 14 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 14 41 1 0 0 0 0 15 42 1 0 0 0 0 15 43 1 0 0 0 0 15 44 1 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 17 20 1 0 0 0 0 18 22 1 0 0 0 0 18 45 1 0 0 0 0 19 21 1 0 0 0 0 19 20 2 0 0 0 0 19 46 1 0 0 0 0 20 47 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 23 48 1 0 0 0 0 24 25 2 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 25 50 1 0 0 0 0 26 27 1 0 0 0 0 27 28 1 0 0 0 0 27 29 2 0 0 0 0 28 51 1 0 0 0 0 30 31 1 0 0 0 0 30 32 1 0 0 0 0 30 52 1 0 0 0 0 31 32 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 M END > 540648 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 13 > 2008 > 540648 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 13 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 70 75 0 0 0 0 0 0 0 0999 V2000 -0.0480 1.3599 0.0035 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1344 2.1021 -0.1280 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3507 1.4703 -0.2609 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0189 -0.0055 0.0025 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2052 -0.6730 -0.1313 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4045 0.0710 -0.2646 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5637 -0.5927 -0.3912 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5814 -1.9041 -0.3910 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4865 -2.6385 -0.2693 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2910 -2.0835 -0.1385 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0793 3.4595 -0.1246 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3176 4.1593 -0.2626 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1808 -2.8471 -0.0147 O 0 0 0 0 0 0 0 0 0 0 0 0 0.3175 -4.1941 -0.1273 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1106 -4.8110 -1.3536 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2537 -6.1769 -1.4736 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6073 -6.9412 -0.3604 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8150 -6.3188 0.8724 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6700 -4.9515 0.9853 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7610 -8.4056 -0.4860 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0839 -9.1986 0.4799 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5226 -9.3168 -1.9707 S 0 0 0 0 0 0 0 0 0 0 0 0 0.9025 -10.8159 -1.1268 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1799 -10.5121 0.2110 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5133 -11.5718 1.0835 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5616 -12.8535 0.6280 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2850 -13.1463 -0.7001 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9567 -12.1347 -1.5743 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0570 5.6667 -0.2368 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3828 6.4161 -0.3846 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1326 7.8634 -0.3598 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3921 8.6139 -0.2606 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0948 10.1142 -0.3178 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1838 10.4725 0.7783 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9242 9.7220 0.6790 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2216 8.2217 0.7362 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9336 11.9198 0.8030 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2362 2.0069 0.1391 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.4048 1.1957 0.2749 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8759 -4.3469 2.1758 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2565 2.0497 -0.3620 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9353 -0.5678 0.1047 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5314 -2.4073 -0.4952 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9802 3.8910 0.5602 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7850 3.8875 -1.2090 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1633 -4.2199 -2.2150 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0921 -6.6554 -2.4283 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0890 -6.9069 1.7358 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7320 -11.3633 2.1204 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8185 -13.6521 1.3082 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3271 -14.1679 -1.0479 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7416 -12.3632 -2.6077 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3944 5.9350 -1.0596 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5896 5.9385 0.7096 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0454 6.1478 0.4382 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8502 6.1443 -1.3310 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8837 8.3763 0.6828 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0446 8.3406 -1.0899 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0247 10.6734 -0.2152 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6279 10.3562 -1.2725 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2718 9.9952 1.5083 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4327 9.9595 -0.2644 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2916 7.6625 0.6337 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6885 7.9797 1.6910 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4827 12.2268 -0.1407 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2565 12.1576 1.6235 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8759 12.4491 0.9446 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2816 1.8355 0.3747 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5138 0.5649 -0.6073 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3103 0.5679 1.1610 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 38 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 46 1 0 0 0 0 16 17 2 0 0 0 0 16 47 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 48 1 0 0 0 0 19 40 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 49 1 0 0 0 0 26 27 1 0 0 0 0 26 50 1 0 0 0 0 27 28 2 0 0 0 0 27 51 1 0 0 0 0 28 52 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 57 1 0 0 0 0 32 58 1 0 0 0 0 33 34 1 0 0 0 0 33 59 1 0 0 0 0 33 60 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 61 1 0 0 0 0 35 62 1 0 0 0 0 36 63 1 0 0 0 0 36 64 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 38 39 1 0 0 0 0 39 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 M END > 691795 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 23 > 2009 > 691795 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 23 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 35 38 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8409 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3464 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6788 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6616 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9881 -0.9593 0.0063 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1705 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0944 -1.5643 -0.7646 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6083 -3.2123 0.6619 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0260 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0353 -3.2705 0.3529 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2904 -2.2128 -0.5405 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5833 -2.0130 -1.0137 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6029 -2.8426 -0.6040 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3555 -3.8867 0.2844 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0794 -4.1075 0.7604 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3745 -4.6966 0.6781 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6692 -4.4179 0.1412 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0007 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4433 -3.0500 -0.0020 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0253 -0.6585 0.0179 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9762 -0.7966 -1.3457 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0652 -3.8764 1.3180 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7872 -1.2071 -1.7032 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6044 -2.6826 -0.9754 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8891 -4.9171 1.4494 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3882 -5.1361 0.5353 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6363 -4.4958 -0.9455 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9705 -3.4094 0.4242 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 22 1 0 0 0 0 1 23 1 0 0 0 0 2 3 1 0 0 0 0 2 24 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 5 2 0 0 0 0 4 9 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 25 1 0 0 0 0 8 9 2 0 0 0 0 8 26 1 0 0 0 0 9 27 1 0 0 0 0 10 12 2 0 0 0 0 10 11 1 0 0 0 0 11 15 1 0 0 0 0 11 28 1 0 0 0 0 12 14 1 0 0 0 0 12 29 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 30 1 0 0 0 0 17 18 1 0 0 0 0 17 31 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 32 1 0 0 0 0 20 21 1 0 0 0 0 21 33 1 0 0 0 0 21 34 1 0 0 0 0 21 35 1 0 0 0 0 M END > 592664 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12g > 2008 > 592664 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12g > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 75 0 0 0 0 0 0 0 0999 V2000 1.4111 1.7775 -0.5366 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9462 0.4969 -0.1842 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7901 -0.6167 -0.3773 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0575 -0.3890 -0.9141 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4353 0.9020 -1.2330 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6284 1.9260 -1.0431 N 0 0 0 0 0 0 0 0 0 0 0 0 0.4044 2.6681 -0.2434 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3663 0.6541 0.3206 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6669 1.9757 0.2789 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9447 2.5774 0.7160 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1375 3.9570 0.6242 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3341 4.5114 1.0284 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3421 3.7033 1.5241 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.1573 2.3356 1.6182 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9654 1.7682 1.2168 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5438 6.0005 0.9305 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.1165 6.3291 -0.3818 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.4704 5.7757 -0.5188 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.1157 7.7806 -0.6080 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0935 -3.8850 1.0390 N 0 0 0 0 0 0 0 0 0 0 0 0 0.3141 -3.9346 -0.1227 N 0 0 0 0 0 0 0 0 0 0 0 0 0.4564 -2.7984 -0.7687 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3454 -1.9831 -0.0213 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7151 -2.6901 1.0859 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2091 -4.9498 2.0385 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1849 -5.3324 2.5397 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1953 -2.4342 -2.0497 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5206 -1.7411 -3.0250 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0859 -1.4085 -4.2176 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4096 -1.7636 -4.4481 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1252 -2.4544 -3.4776 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5232 -2.7893 -2.2833 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0227 -1.4247 -5.6587 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.9810 -2.2197 -6.1745 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3128 -3.2314 -5.5873 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.5717 -1.8933 -7.3412 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.6657 -2.7156 -7.8636 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1195 -0.7161 -8.0869 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7365 -1.2127 -1.0784 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4170 1.0755 -1.6484 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4437 3.6279 -0.3781 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0096 -0.1351 0.6807 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3514 4.5888 0.2378 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2771 4.1424 1.8393 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9479 1.7105 2.0062 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8223 0.7003 1.2907 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2267 6.3237 1.7162 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5877 6.5106 1.0477 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.8435 5.9730 -1.5238 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4423 4.6998 -0.3464 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.1299 6.2437 0.2120 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7094 8.2691 0.1646 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0923 8.1537 -0.5700 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5449 7.9960 -1.5865 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3860 -2.3520 1.8619 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6850 -5.8209 1.5879 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8125 -4.5986 2.8756 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0989 -6.1247 3.2833 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6607 -4.4614 2.9902 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7882 -5.6837 1.7026 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5492 -1.4646 -2.8463 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4680 -0.8714 -4.9733 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1537 -2.7293 -3.6590 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0798 -3.3262 -1.5294 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7582 -0.6174 -6.1270 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6162 -2.3379 -7.4866 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6642 -2.6731 -8.9527 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5310 -3.7477 -7.5401 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3603 -0.1893 -7.5088 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6965 -1.0307 -9.0409 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9654 -0.0523 -8.2657 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 7 1 0 0 0 0 2 3 2 0 0 0 0 2 8 1 0 0 0 0 3 4 1 0 0 0 0 3 23 1 0 0 0 0 4 5 2 0 0 0 0 4 39 1 0 0 0 0 5 6 1 0 0 0 0 5 40 1 0 0 0 0 7 9 1 0 0 0 0 7 41 1 0 0 0 0 8 9 2 0 0 0 0 8 42 1 0 0 0 0 9 10 1 0 0 0 0 10 11 1 0 0 0 0 10 15 2 0 0 0 0 11 12 2 0 0 0 0 11 43 1 0 0 0 0 12 13 1 0 0 0 0 12 16 1 0 0 0 0 13 14 2 0 0 0 0 13 44 1 0 0 0 0 14 15 1 0 0 0 0 14 45 1 0 0 0 0 15 46 1 0 0 0 0 16 17 1 0 0 0 0 16 47 1 0 0 0 0 16 48 1 0 0 0 0 17 18 1 0 0 0 0 17 19 1 0 0 0 0 18 49 1 0 0 0 0 18 50 1 0 0 0 0 18 51 1 0 0 0 0 19 52 1 0 0 0 0 19 53 1 0 0 0 0 19 54 1 0 0 0 0 20 21 1 0 0 0 0 20 24 1 0 0 0 0 20 25 1 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 27 1 0 0 0 0 23 24 2 0 0 0 0 24 55 1 0 0 0 0 25 26 1 0 0 0 0 25 56 1 0 0 0 0 25 57 1 0 0 0 0 26 58 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 27 28 1 0 0 0 0 27 32 2 0 0 0 0 28 29 2 0 0 0 0 28 61 1 0 0 0 0 29 30 1 0 0 0 0 29 62 1 0 0 0 0 30 31 2 0 0 0 0 30 33 1 0 0 0 0 31 32 1 0 0 0 0 31 63 1 0 0 0 0 32 64 1 0 0 0 0 33 34 1 0 0 0 0 33 65 1 0 0 0 0 34 35 2 0 0 0 0 34 36 1 0 0 0 0 36 37 1 0 0 0 0 36 38 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 38 69 1 0 0 0 0 38 70 1 0 0 0 0 38 71 1 0 0 0 0 M END > 722556 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20420387 > J. Med. Chem.|2010|53|10|3973 > "17k, GSK-1070916" > 2010 > 722556 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 20420387 > J. Med. Chem.|2010|53|10|3973 > "17k, GSK-1070916" > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 -0.0207 1.3617 -0.0360 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1736 2.0955 -0.0561 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3928 1.4547 -0.0688 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0008 -0.0042 -0.0286 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2254 -0.6797 -0.0413 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4367 0.0553 -0.0615 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5986 -0.6167 -0.0727 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6082 -1.9284 -0.0651 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5028 -2.6562 -0.0468 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3019 -2.0928 -0.0339 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1280 3.4531 -0.0636 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3786 4.1442 -0.0846 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1571 -2.8645 -0.0144 N 0 0 0 0 0 0 0 0 0 0 0 0 0.2492 -4.2518 -0.1280 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6486 -5.0651 0.5557 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5607 -6.4355 0.4464 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4309 -7.0088 -0.3522 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3318 -6.1893 -1.0387 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2348 -4.8184 -0.9290 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5281 -8.4780 -0.4711 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2561 -9.3188 0.1161 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7234 -9.3304 -1.4384 S 0 0 0 0 0 0 0 0 0 0 0 0 1.0395 -10.8769 -0.9442 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0446 -10.6296 -0.0942 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7540 -11.7348 0.4259 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3915 -13.0054 0.0988 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6805 -13.2418 -0.7503 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3976 -12.1851 -1.2647 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1273 5.6534 -0.0902 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4663 6.3933 -0.1128 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2250 7.8423 -0.1182 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4744 8.5851 0.0987 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1944 10.0869 0.0070 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1848 10.4564 1.0088 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9354 9.7137 0.7919 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2154 8.2118 0.8836 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9435 11.9055 1.0034 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2121 2.0168 -0.0179 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.3938 1.2137 0.0082 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5666 -6.8967 -2.0330 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.3082 2.0276 -0.0846 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9265 -0.5603 -0.0128 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5607 -2.4373 -0.0745 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9571 3.8755 0.7992 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9330 3.8648 -0.9806 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7111 -2.4420 0.0783 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4155 -4.6215 1.1733 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2580 -7.0659 0.9782 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9299 -4.1842 -1.4591 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5906 -11.5704 1.0888 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9444 -13.8394 0.5052 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9573 -14.2552 -1.0010 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2315 -12.3697 -1.9257 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5487 5.9221 -0.9741 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5729 5.9328 0.8057 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0449 6.1246 0.7710 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0207 6.1139 -1.0088 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8712 8.3488 1.0860 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2017 8.3036 -0.6628 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1141 10.6405 0.1962 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8232 10.3275 -0.9892 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2081 9.9952 1.5534 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5385 9.9500 -0.1954 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2957 7.6582 0.6944 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5865 7.9713 1.8799 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5876 12.2109 0.0195 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1923 12.1515 1.7540 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8715 12.4292 1.2329 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4217 0.5795 -0.8779 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3892 0.5895 0.9018 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2718 1.8595 0.0206 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 38 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 13 46 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 47 1 0 0 0 0 16 17 2 0 0 0 0 16 48 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 40 1 0 0 0 0 19 49 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 50 1 0 0 0 0 26 27 1 0 0 0 0 26 51 1 0 0 0 0 27 28 2 0 0 0 0 27 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 62 1 0 0 0 0 35 63 1 0 0 0 0 36 64 1 0 0 0 0 36 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 38 39 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 M END > 691687 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 15 > 2009 > 691687 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 15 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 40 44 0 0 0 0 0 0 0 0999 V2000 0.0339 1.3720 -0.3113 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1902 2.0888 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3764 1.4171 0.2598 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4116 0.0400 0.2370 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2543 -0.6826 -0.0608 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0633 -0.0069 -0.3350 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2900 -2.1595 -0.0862 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2785 -2.9171 -0.3494 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7180 -3.1352 0.2303 S 0 0 0 0 0 0 0 0 0 0 0 0 1.7864 -4.6071 -0.0329 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4689 -4.2477 -0.3395 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4651 -5.2772 -0.5910 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0867 -6.5833 -0.5344 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2217 -6.9313 -0.2292 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1551 -5.9502 0.0188 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1584 3.4845 0.0093 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1332 4.1855 0.6886 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0408 3.5541 1.4215 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9810 4.2149 2.0780 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0841 5.5224 2.0535 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1957 5.5985 0.6179 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2173 6.2599 1.3432 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2972 7.6574 1.2957 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3887 8.3595 0.5578 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3814 7.7071 -0.1494 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2839 6.3467 -0.1345 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4896 10.0916 0.5003 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -1.1186 2.0273 -0.5712 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2716 1.9757 0.4902 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3339 -0.4804 0.4491 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8333 -0.5631 -0.5653 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4879 -5.0257 -0.8298 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8134 -7.3583 -0.7290 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5079 -7.9718 -0.1874 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1732 -6.2215 0.2559 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4510 3.9612 -0.4524 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6955 3.6522 2.6604 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0726 8.1762 1.8398 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6745 8.2856 -0.7256 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4990 5.8515 -0.6869 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 28 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 29 1 0 0 0 0 4 5 1 0 0 0 0 4 30 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 31 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 32 1 0 0 0 0 13 14 1 0 0 0 0 13 33 1 0 0 0 0 14 15 2 0 0 0 0 14 34 1 0 0 0 0 15 35 1 0 0 0 0 16 17 1 0 0 0 0 16 36 1 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 18 19 1 0 0 0 0 19 20 2 0 0 0 0 19 37 1 0 0 0 0 20 22 1 0 0 0 0 21 22 1 0 0 0 0 21 26 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 23 38 1 0 0 0 0 24 25 2 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 39 1 0 0 0 0 26 40 1 0 0 0 0 M END > 557698 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "23, Table 4" > 2009 > 557698 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "23, Table 4" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 75 80 0 0 0 0 0 0 0 0999 V2000 -0.0207 1.3617 -0.0360 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1735 2.0955 -0.0562 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3927 1.4547 -0.0695 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0008 -0.0042 -0.0287 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2253 -0.6797 -0.0414 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4367 0.0553 -0.0623 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5985 -0.6167 -0.0741 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6082 -1.9284 -0.0665 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5028 -2.6562 -0.0476 N 0 0 0 0 0 0 0 0 0 0 0 0 1.3019 -2.0928 -0.0342 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1279 3.4532 -0.0632 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3785 4.1442 -0.0844 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1572 -2.8645 -0.0141 N 0 0 0 0 0 0 0 0 0 0 0 0 0.2492 -4.2520 -0.1278 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6482 -5.0654 0.5561 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5599 -6.4356 0.4459 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4316 -7.0079 -0.3540 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3308 -6.1885 -1.0398 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2344 -4.8189 -0.9294 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5293 -8.4773 -0.4740 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2506 -9.3184 0.1169 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7201 -9.3282 -1.4483 S 0 0 0 0 0 0 0 0 0 0 0 0 1.0356 -10.8755 -0.9570 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0394 -10.6299 -0.0951 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7464 -11.7348 0.4291 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3878 -13.0056 0.1014 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6828 -13.2440 -0.7563 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3914 -12.1825 -1.2842 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1272 5.6534 -0.0894 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4662 6.3933 -0.1121 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2250 7.8424 -0.1168 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4744 8.5850 0.0999 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1944 10.0869 0.0089 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1850 10.4561 1.0111 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9355 9.7134 0.7943 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2156 8.2115 0.8854 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9437 11.9051 1.0063 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0299 -14.5195 -1.0738 O 0 0 0 0 0 0 0 0 0 0 0 0 0.2525 -15.5675 -0.4914 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2122 2.0168 -0.0179 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.3938 1.2137 0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3081 2.0276 -0.0857 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9265 -0.5603 -0.0127 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5607 -2.4373 -0.0764 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9573 3.8752 0.7992 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9327 3.8652 -0.9806 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7110 -2.4420 0.0791 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4147 -4.6223 1.1746 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2565 -7.0667 0.9777 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0987 -6.6282 -1.6591 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9296 -4.1847 -1.4595 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.5792 -11.5692 1.0965 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9395 -13.8387 0.5113 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2221 -12.3654 -1.9496 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5484 5.9225 -0.9729 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5731 5.9325 0.8068 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0450 6.1243 0.7715 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0204 6.1143 -1.0083 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8715 8.3484 1.0871 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2015 8.3038 -0.6619 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1141 10.6405 0.1980 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8229 10.3278 -0.9872 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2085 9.9946 1.5561 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5384 9.9501 -0.1928 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2958 7.6580 0.6962 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5870 7.9706 1.8814 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5876 12.2109 0.0226 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1928 12.1509 1.7572 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8718 12.4287 1.2357 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7879 -15.4620 -0.7987 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6342 -16.5321 -0.8261 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3183 -15.5080 0.5950 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4218 0.5795 -0.8777 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3892 0.5895 0.9019 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2718 1.8595 0.0207 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 40 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 42 1 0 0 0 0 4 5 2 0 0 0 0 4 43 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 44 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 45 1 0 0 0 0 12 46 1 0 0 0 0 13 14 1 0 0 0 0 13 47 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 48 1 0 0 0 0 16 17 2 0 0 0 0 16 49 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 50 1 0 0 0 0 19 51 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 52 1 0 0 0 0 26 27 1 0 0 0 0 26 53 1 0 0 0 0 27 28 2 0 0 0 0 27 38 1 0 0 0 0 28 54 1 0 0 0 0 29 30 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 30 31 1 0 0 0 0 30 57 1 0 0 0 0 30 58 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 61 1 0 0 0 0 33 62 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 65 1 0 0 0 0 36 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 37 69 1 0 0 0 0 38 39 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 39 72 1 0 0 0 0 40 41 1 0 0 0 0 41 73 1 0 0 0 0 41 74 1 0 0 0 0 41 75 1 0 0 0 0 M END > 691688 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 16 > 2009 > 691688 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 16 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 61 65 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8410 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3465 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6789 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -0.9593 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1704 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0935 -1.5673 -0.7685 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6094 -3.2092 0.6658 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0263 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0372 -3.2646 0.3601 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2898 -2.2147 -0.5431 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5821 -2.0169 -1.0189 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6024 -2.8444 -0.6065 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3563 -3.8843 0.2871 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0822 -4.0984 0.7716 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3760 -4.6919 0.6836 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6701 -4.4152 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6803 -5.4202 0.7012 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0658 -5.1240 0.1236 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0358 -6.0889 0.6585 N 0 0 0 0 0 0 0 0 0 0 0 0 14.3210 -5.9899 -0.0473 C 0 0 0 0 0 0 0 0 0 0 0 0 15.3256 -6.9526 0.5902 C 0 0 0 0 0 0 0 0 0 0 0 0 14.7965 -8.3221 0.5254 N 0 0 0 0 0 0 0 0 0 0 0 0 13.5114 -8.4211 1.2312 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5068 -7.4584 0.5937 C 0 0 0 0 0 0 0 0 0 0 0 0 15.7665 -9.2870 1.0602 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0967 -10.6545 1.2088 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0009 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4432 -3.0501 -0.0017 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0252 -0.6586 0.0188 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9745 -0.8022 -1.3527 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0677 -3.8688 1.3275 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7850 -1.2142 -1.7123 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6034 -2.6859 -0.9799 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8929 -4.9051 1.4642 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6362 -4.4983 -0.9421 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9712 -3.4052 0.4222 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7142 -5.3372 1.7875 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3792 -6.4302 0.4232 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0319 -5.2070 -0.9627 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3670 -4.1140 0.4016 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1811 -6.2522 -1.0960 H 0 0 0 0 0 0 0 0 0 0 0 0 14.6983 -4.9699 0.0256 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2709 -6.9020 0.0500 H 0 0 0 0 0 0 0 0 0 0 0 0 15.4860 -6.6737 1.6316 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1341 -9.4412 1.1583 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6512 -8.1589 2.2799 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5614 -7.5090 1.1339 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3463 -7.7373 -0.4477 H 0 0 0 0 0 0 0 0 0 0 0 0 16.6120 -9.3689 0.3771 H 0 0 0 0 0 0 0 0 0 0 0 0 16.1181 -8.9469 2.0343 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2512 -10.5727 1.8919 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7451 -10.9947 0.2348 H 0 0 0 0 0 0 0 0 0 0 0 0 15.8164 -11.3705 1.6057 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 32 1 0 0 0 0 1 33 1 0 0 0 0 2 3 1 0 0 0 0 2 34 1 0 0 0 0 3 5 1 0 0 0 0 3 13 2 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 6 10 1 0 0 0 0 7 8 1 0 0 0 0 7 35 1 0 0 0 0 8 9 2 0 0 0 0 8 36 1 0 0 0 0 9 37 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 38 1 0 0 0 0 12 14 1 0 0 0 0 12 39 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 18 1 0 0 0 0 17 41 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 42 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 43 1 0 0 0 0 21 44 1 0 0 0 0 22 23 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 29 1 0 0 0 0 25 26 1 0 0 0 0 25 49 1 0 0 0 0 25 50 1 0 0 0 0 26 27 1 0 0 0 0 26 51 1 0 0 0 0 26 52 1 0 0 0 0 27 28 1 0 0 0 0 27 30 1 0 0 0 0 28 29 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 30 31 1 0 0 0 0 30 57 1 0 0 0 0 30 58 1 0 0 0 0 31 59 1 0 0 0 0 31 60 1 0 0 0 0 31 61 1 0 0 0 0 M END > 592608 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12a > 2008 > 592608 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12a > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 74 79 0 0 0 0 0 0 0 0999 V2000 -1.0438 1.2649 -0.6042 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3025 1.8195 -0.3337 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3355 1.0307 0.1222 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8148 -0.0693 -0.4212 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8463 -0.8919 0.0469 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1231 -0.3395 0.3167 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.0981 -1.1522 0.7535 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.8693 -2.4323 0.9259 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6939 -2.9919 0.6872 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.6624 -2.2799 0.2527 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5056 3.1493 -0.5230 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.8096 3.6547 -0.2294 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0411 2.0630 -1.0589 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2168 1.4382 -1.3220 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4419 -2.8771 0.0073 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3126 -4.2631 0.0991 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3748 -5.0847 -0.2629 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2481 -6.4539 -0.1787 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0518 -7.0166 0.2707 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0132 -6.1889 0.6335 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8805 -4.8208 0.5472 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0872 -8.4847 0.3626 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1009 -9.1579 -0.0683 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1013 -9.5629 1.0811 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.0759 -10.9508 0.7260 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0848 -10.4924 0.0922 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0596 -11.4412 -0.2883 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8684 -12.7660 -0.0421 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7144 -13.2124 0.5865 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2530 -12.3113 0.9706 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8463 5.1599 -0.5011 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2425 5.7010 -0.1867 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2778 7.1462 -0.4476 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.6536 7.6590 -0.3866 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.6388 9.1766 -0.5842 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0187 9.4934 -1.8784 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.6429 8.9806 -1.9394 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6577 7.4630 -1.7417 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.0540 10.9386 -2.1393 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3059 -6.7922 1.1194 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3021 1.4659 0.3284 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1572 -0.4876 -0.6371 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6761 -3.0575 1.2789 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5440 3.1536 -0.8600 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0437 3.4689 0.8189 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0879 0.6678 -2.0823 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9261 2.1852 -1.6782 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5959 0.9848 -0.4061 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3256 -2.3330 -0.2290 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2999 -4.6488 -0.6100 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0734 -7.0914 -0.4596 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7036 -4.1802 0.8276 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9640 -11.1126 -0.7788 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6236 -13.4785 -0.3397 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5755 -14.2668 0.7749 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1508 -12.6593 1.4597 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1120 5.6610 0.1296 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6122 5.3457 -1.5493 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.9769 5.1999 -0.8174 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4766 5.5152 0.8615 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.2496 7.1956 -1.1728 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0868 7.4230 0.5854 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.6608 9.5554 -0.5682 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0655 9.6422 0.2174 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.2097 9.2165 -2.9114 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0469 9.4440 -1.1532 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6357 7.0842 -1.7577 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2310 6.9974 -2.5434 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5103 11.4630 -1.3535 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5888 11.1453 -3.1031 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0891 11.2799 -2.1548 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9859 -6.9207 0.2773 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7611 -6.1307 1.8564 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1055 -7.7615 1.5758 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 15 16 1 0 0 0 0 15 49 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 51 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 40 1 0 0 0 0 21 52 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 40 72 1 0 0 0 0 40 73 1 0 0 0 0 40 74 1 0 0 0 0 M END > 691720 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 11 > 2009 > 691720 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 11 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 59 63 0 0 0 999 V2000 -0.0033 1.3595 -0.1110 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0033 -0.0022 0.0202 N 0 0 0 0 0 0 0 0 0 0 0 0 0.9157 2.3071 0.0440 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6098 3.5776 -0.1604 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2486 -0.5020 -0.2654 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3048 1.7388 -0.5035 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3118 9.9440 -0.3674 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.0812 0.5008 -0.5852 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6062 3.9674 -0.5239 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6189 12.7157 0.2060 N 0 0 0 0 0 0 0 0 0 0 0 0 1.5949 4.5373 0.0117 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6340 8.5854 -0.2725 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5780 3.0901 -0.7089 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1565 -0.8085 0.4088 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4254 10.7104 -0.9438 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0747 10.4863 0.9426 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8790 8.1360 -0.6929 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2886 7.6876 0.2485 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4947 11.9493 0.7824 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0053 12.1734 -1.1040 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2722 5.8971 -0.0836 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1972 6.7958 -0.5985 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0293 6.3472 0.3420 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2806 14.1417 0.1064 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8387 -1.5719 1.6961 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4828 -1.8034 -0.7068 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6941 -2.6455 -0.3010 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0500 -2.4140 2.1019 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3762 -3.4089 0.9863 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5186 -1.5473 -0.2377 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1221 0.4107 -0.8585 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5077 4.2674 0.1981 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5648 3.4144 -1.0046 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0134 -0.1558 0.5756 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2891 10.6505 -0.2816 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6847 10.2976 -1.9187 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9089 9.9102 1.3430 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7721 10.4239 1.6262 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5982 8.8349 -1.0939 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2550 8.0378 0.5798 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7541 12.3621 1.7573 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3585 12.0092 0.1203 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1585 12.2358 -1.7876 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8395 12.7495 -1.5044 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1654 6.4463 -0.9254 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6884 5.6490 0.7465 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0637 14.5340 1.1000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1219 14.6856 -0.3232 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5948 14.2639 -0.5314 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6063 -0.8631 2.4909 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0182 -2.2246 1.5293 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6259 -2.4562 -0.8736 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7092 -1.2596 -1.6239 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9265 -3.3543 -1.0958 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5509 -1.9928 -0.1342 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9068 -1.7613 2.2687 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8235 -2.9578 3.0190 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5194 -4.0616 0.8195 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2391 -4.0088 1.2754 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 3 2 0 0 0 0 1 6 1 0 0 0 0 2 5 1 0 0 0 0 2 14 1 0 0 0 0 3 4 1 0 0 0 0 4 11 1 0 0 0 0 4 9 2 0 0 0 0 5 8 2 0 0 0 0 5 30 1 0 0 0 0 6 8 1 0 0 0 0 6 13 2 0 0 0 0 7 12 1 0 0 0 0 7 15 1 0 0 0 0 7 16 1 0 0 0 0 8 31 1 0 0 0 0 9 13 1 0 0 0 0 10 19 1 0 0 0 0 10 24 1 0 0 0 0 10 20 1 0 0 0 0 11 21 1 0 0 0 0 11 32 1 0 0 0 0 12 18 1 0 0 0 0 12 17 2 0 0 0 0 13 33 1 0 0 0 0 14 25 1 0 0 0 0 14 26 1 0 0 0 0 14 34 1 0 0 0 0 15 20 1 0 0 0 0 15 35 1 0 0 0 0 15 36 1 0 0 0 0 16 19 1 0 0 0 0 16 37 1 0 0 0 0 16 38 1 0 0 0 0 17 22 1 0 0 0 0 17 39 1 0 0 0 0 18 23 2 0 0 0 0 18 40 1 0 0 0 0 19 41 1 0 0 0 0 19 42 1 0 0 0 0 20 43 1 0 0 0 0 20 44 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 45 1 0 0 0 0 23 46 1 0 0 0 0 24 47 1 0 0 0 0 24 48 1 0 0 0 0 24 49 1 0 0 0 0 25 28 1 0 0 0 0 25 50 1 0 0 0 0 25 51 1 0 0 0 0 26 27 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 27 29 1 0 0 0 0 27 54 1 0 0 0 0 27 55 1 0 0 0 0 28 29 1 0 0 0 0 28 56 1 0 0 0 0 28 57 1 0 0 0 0 29 58 1 0 0 0 0 29 59 1 0 0 0 0 M END > 463095 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 16949284 > Bioorg. Med. Chem. Lett.|2006|16|22|5778 > 2 > 2006 > 463095 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 16949284 > Bioorg. Med. Chem. Lett.|2006|16|22|5778 > 2 > 2006 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 47 50 0 0 0 0 0 0 0 0999 V2000 -0.0180 1.4768 0.0102 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1425 2.2531 0.0310 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6717 3.6895 0.0316 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7949 3.6336 0.0095 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1623 2.3400 0.0035 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3132 1.9441 -0.0140 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5272 1.7866 0.0487 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1977 1.2509 1.1139 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4664 0.9424 0.7464 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4809 1.8061 -1.0771 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6766 1.2653 -0.5787 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.7775 1.1523 -1.4219 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.6861 1.5696 -2.7317 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5032 2.1033 -3.2226 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4023 2.2238 -2.4030 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5108 -0.6895 -1.1010 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5339 -2.0735 -1.1042 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0499 -2.7806 -0.0087 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4578 -2.0991 1.0923 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4824 -0.7151 1.0998 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9309 -2.7929 2.1620 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.4377 -2.0289 3.2582 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0727 -4.1414 -0.0142 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2439 -4.7727 0.5070 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0298 -2.7424 -2.1794 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5097 -1.9530 -3.2697 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0412 4.2062 -0.8542 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0146 4.1967 0.9334 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3942 4.3962 0.0046 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7802 1.0964 2.0979 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1322 0.5497 1.3324 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.7028 0.7376 -1.0500 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5431 1.4800 -3.3827 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4453 2.4261 -4.2516 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4827 2.6399 -2.7872 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8861 -0.1409 -1.9522 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8764 -0.1863 1.9550 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7821 -2.7030 4.0424 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6479 -1.3884 3.6506 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2697 -1.4126 2.9176 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1127 -4.4629 -0.0738 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3806 -4.4817 1.5485 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1319 -5.8551 0.4439 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6982 -1.3368 -3.6569 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3204 -1.3114 -2.9245 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8764 -2.6088 -4.0593 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 7 1 0 0 0 0 3 4 1 0 0 0 0 3 28 1 0 0 0 0 3 29 1 0 0 0 0 4 5 1 0 0 0 0 4 30 1 0 0 0 0 5 6 2 0 0 0 0 7 8 2 0 0 0 0 7 10 1 0 0 0 0 8 9 1 0 0 0 0 8 31 1 0 0 0 0 9 11 1 0 0 0 0 9 32 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 33 1 0 0 0 0 13 14 1 0 0 0 0 13 34 1 0 0 0 0 14 15 2 0 0 0 0 14 35 1 0 0 0 0 15 36 1 0 0 0 0 16 17 2 0 0 0 0 16 21 1 0 0 0 0 17 18 1 0 0 0 0 17 37 1 0 0 0 0 18 19 2 0 0 0 0 18 26 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 26 27 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 M END > 548944 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 2 > 2008 > 548944 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 18529047 > J. Med. Chem.|2008|51|13|3814 > 2 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 25 27 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5044 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3852 1.9325 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8405 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3470 -0.3795 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6796 -1.7492 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6616 -2.7033 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6593 -2.3069 -0.0050 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9875 -0.9591 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0929 -2.1706 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6318 -3.2200 0.6619 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9620 -3.2929 0.3808 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2723 -2.3052 -0.4884 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0964 -1.5904 -0.7602 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8587 -0.0260 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5309 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6959 2.8514 0.0007 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9085 -3.7546 -0.0286 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4428 -3.0502 -0.0024 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0247 -0.6585 0.0185 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1461 -3.8106 1.2586 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6532 -4.0178 0.7848 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2503 -2.1023 -0.8993 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0025 -0.7389 -1.4178 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 16 1 0 0 0 0 1 17 1 0 0 0 0 2 3 1 0 0 0 0 2 18 1 0 0 0 0 3 5 1 0 0 0 0 3 15 2 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 7 19 1 0 0 0 0 8 9 2 0 0 0 0 8 20 1 0 0 0 0 9 21 1 0 0 0 0 10 11 1 0 0 0 0 10 14 2 0 0 0 0 11 12 1 0 0 0 0 11 22 1 0 0 0 0 12 13 2 0 0 0 0 12 23 1 0 0 0 0 13 14 1 0 0 0 0 13 24 1 0 0 0 0 14 25 1 0 0 0 0 M END > 592604 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 1 > 2008 > 592604 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 1 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 61 68 0 1 0 999 V2000 0.3109 1.4837 0.0039 C 0 0 1 0 0 0 0 0 0 0 0 0 0.0849 0.0419 -0.1094 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7445 0.6016 -1.8103 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8961 -0.8263 -0.8244 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0581 -0.5842 -1.5664 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6778 1.8214 -0.0568 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3433 1.9119 -1.2962 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7098 -1.6382 -2.2099 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3853 -2.1299 -0.7266 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1871 -2.9494 -2.1149 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0325 -3.1775 -1.3740 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9421 -0.6674 0.4666 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8403 0.3349 -2.5929 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5240 2.2389 -1.0228 C 0 0 1 0 0 0 0 0 0 0 0 0 3.8690 -1.0507 -2.8751 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8082 -2.0290 0.1153 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5339 2.6721 -2.3396 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6385 -4.2313 -2.6780 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8085 -5.2225 -2.3111 N 0 0 0 0 0 0 0 0 0 0 0 0 0.1170 2.0916 -2.4074 C 0 0 1 0 0 0 0 0 0 0 0 0 0.7458 -4.6559 -1.4730 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6238 -4.3740 -3.3764 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.1984 1.9114 1.3818 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1800 0.6712 -2.7768 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.8473 1.7002 -1.0504 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.9947 -0.2442 1.2773 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8301 1.1812 -3.0915 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7154 -2.9900 0.5607 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8797 -1.6144 -3.6565 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0451 0.2531 -3.4714 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8547 2.6511 -1.4013 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8851 -1.2121 1.7111 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8238 0.6035 -3.8632 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8499 -0.7528 -4.1387 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7521 -2.5449 1.3646 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2559 2.4845 -1.1305 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5662 3.2939 -0.7521 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4824 3.7253 -2.0633 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0137 2.5746 -3.3134 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8972 -6.1562 -2.5587 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4701 2.6388 -3.1449 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7680 -5.1093 -0.4821 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2261 -4.8190 -1.9388 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0372 1.1376 2.1125 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2828 2.8450 1.6733 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2779 2.0563 1.3413 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9968 0.4792 -3.3372 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1108 0.7932 1.5544 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8221 2.2412 -2.8844 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6149 -4.0310 0.2915 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9035 -2.6721 -3.8740 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9719 -0.8024 -3.7335 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9037 0.4065 -2.8177 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1686 0.8449 -4.3783 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8539 3.4653 -0.6766 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6486 3.0489 -2.3949 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.8300 2.1643 -1.3999 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7111 -0.9165 2.3409 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6051 1.2324 -4.2638 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6495 -1.1498 -4.7465 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4759 -3.2577 1.7311 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 1 0 0 0 0 1 14 1 0 0 0 0 1 23 1 0 0 0 0 2 4 1 0 0 0 0 2 12 1 0 0 0 0 3 7 1 0 0 0 0 3 13 1 0 0 0 0 3 5 1 0 0 0 0 4 5 1 0 0 0 0 4 9 2 0 0 0 0 5 8 2 0 0 0 0 6 7 1 0 0 0 0 7 17 1 0 0 0 0 7 36 1 0 0 0 0 8 15 1 0 0 0 0 8 10 1 0 0 0 0 9 11 1 0 0 0 0 9 16 1 0 0 0 0 10 11 2 0 0 0 0 10 18 1 0 0 0 0 11 21 1 0 0 0 0 12 16 2 0 0 0 0 12 26 1 0 0 0 0 13 15 2 0 0 0 0 13 27 1 0 0 0 0 14 20 1 0 0 0 0 14 25 1 0 0 0 0 14 37 1 0 0 0 0 15 29 1 0 0 0 0 16 28 1 0 0 0 0 17 20 1 0 0 0 0 17 38 1 0 0 0 0 17 39 1 0 0 0 0 18 22 2 0 0 0 0 18 19 1 0 0 0 0 19 21 1 0 0 0 0 19 40 1 0 0 0 0 20 24 1 0 0 0 0 20 41 1 0 0 0 0 21 42 1 0 0 0 0 21 43 1 0 0 0 0 23 44 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 30 1 0 0 0 0 24 47 1 0 0 0 0 25 31 1 0 0 0 0 26 32 2 0 0 0 0 26 48 1 0 0 0 0 27 33 2 0 0 0 0 27 49 1 0 0 0 0 28 35 2 0 0 0 0 28 50 1 0 0 0 0 29 34 2 0 0 0 0 29 51 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 32 35 1 0 0 0 0 32 58 1 0 0 0 0 33 34 1 0 0 0 0 33 59 1 0 0 0 0 34 60 1 0 0 0 0 35 61 1 0 0 0 0 M END > 186358 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19397322 > J. Med. Chem.|2009|52|10|3191 > staurosporine > 2009 > 186358 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 15288657 > Bioorg. Med. Chem. Lett.|2004|14|17|4505 > 2 > 2004 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 66 70 0 0 0 0 0 0 0 0999 V2000 0.0199 1.4155 -0.0512 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7423 1.3713 0.9255 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4000 0.8186 -1.1982 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.0207 9.1168 1.3180 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.4708 10.4177 1.4244 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.7795 10.7300 1.0802 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.6353 9.7337 0.6290 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.1851 8.4327 0.5231 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.8765 8.1206 0.8668 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.4196 6.8007 0.7589 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.1066 6.5497 0.3969 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6603 5.3006 0.4030 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.0706 7.3698 -0.3260 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3264 7.5629 0.0472 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5623 6.0842 -0.3417 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4060 5.0411 0.0690 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5075 4.6517 -0.0554 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1567 5.8207 -0.7964 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.4739 3.4995 0.0090 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8377 3.6824 0.0814 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3968 2.4579 0.1509 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4740 1.5560 0.1089 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2776 2.1185 0.0209 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8333 2.1911 0.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.2360 12.0485 1.1884 N 0 0 0 0 0 0 0 0 0 0 0 0 -9.6422 12.1546 0.7752 C 0 0 0 0 0 0 0 0 0 0 0 0 -10.1252 13.5919 0.9831 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.2799 14.5075 0.2041 N 0 0 0 0 0 0 0 0 0 0 0 0 -7.8737 14.4015 0.6173 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.3907 12.9641 0.4095 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7591 15.8915 0.3177 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7533 4.2172 -0.8054 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1316 5.0808 1.3642 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6839 0.1164 -1.2679 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1764 0.8539 -1.9776 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.0016 8.8747 1.5815 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.8053 11.1924 1.7757 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.6531 9.9764 0.3616 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.8507 7.6579 0.1722 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0230 6.0625 0.9377 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4499 8.2066 -0.6104 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1677 5.5987 -1.8635 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5594 6.7174 -0.6315 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2614 2.0996 -0.7399 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9903 1.2628 0.8075 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3169 3.0124 0.7872 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.7328 11.8893 -0.2781 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.2496 11.4766 1.3748 H 0 0 0 0 0 0 0 0 0 0 0 0 -11.1594 13.6798 0.6502 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.0603 13.8480 2.0406 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.2663 15.0795 0.0177 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.7831 14.6667 1.6707 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.3565 12.8763 0.7424 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.4556 12.7080 -0.6480 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.7365 16.1992 1.3632 H 0 0 0 0 0 0 0 0 0 0 0 0 -9.1157 16.5480 -0.2682 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.7805 15.9544 -0.0575 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4978 3.9783 -1.8377 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4827 5.0270 -0.7896 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1776 3.3367 -0.3230 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3340 4.2443 1.8853 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5682 5.9152 1.3183 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0293 5.3886 1.9005 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4924 0.8154 -1.0544 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6973 -0.6898 -0.5345 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8170 -0.2990 -2.2669 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1 0 0 0 0 1 2 2 0 0 0 0 1 23 1 0 0 0 0 3 34 1 0 0 0 0 3 35 1 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 4 36 1 0 0 0 0 5 6 1 0 0 0 0 5 37 1 0 0 0 0 6 7 2 0 0 0 0 6 25 1 0 0 0 0 7 8 1 0 0 0 0 7 38 1 0 0 0 0 8 9 2 0 0 0 0 8 39 1 0 0 0 0 9 10 1 0 0 0 0 10 11 1 0 0 0 0 10 40 1 0 0 0 0 11 12 2 0 0 0 0 11 14 1 0 0 0 0 12 16 1 0 0 0 0 13 15 1 0 0 0 0 13 14 2 0 0 0 0 13 41 1 0 0 0 0 15 18 1 0 0 0 0 15 16 2 0 0 0 0 16 20 1 0 0 0 0 17 19 1 0 0 0 0 17 18 1 0 0 0 0 17 32 1 0 0 0 0 17 33 1 0 0 0 0 18 42 1 0 0 0 0 18 43 1 0 0 0 0 19 20 2 0 0 0 0 19 23 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 2 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 26 1 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 29 1 0 0 0 0 28 31 1 0 0 0 0 29 30 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 61 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 34 64 1 0 0 0 0 34 65 1 0 0 0 0 34 66 1 0 0 0 0 M END > 659790 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19603809 > J. Med. Chem.|2009|52|16|5152 > "28, PHA-848125" > 2009 > 659790 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19603809 > J. Med. Chem.|2009|52|16|5152 > "28, PHA-848125" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 71 76 0 0 0 0 0 0 0 0999 V2000 0.0581 1.3585 -0.6296 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0574 -0.0328 -0.4589 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2077 -0.6976 -0.0954 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1994 2.0847 -0.4391 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3820 1.4331 -0.0694 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3890 0.0268 0.1050 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5361 -0.5733 0.4596 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6272 0.1320 0.6403 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6680 1.4463 0.4895 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5911 2.1378 0.1403 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0903 -0.7331 -0.6535 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.0271 -2.1480 -0.4638 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6484 3.5087 -0.0143 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8723 4.1710 0.0828 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9247 5.4587 0.6067 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1315 6.1147 0.7094 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3049 5.4861 0.2875 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2502 4.1908 -0.2387 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0374 3.5403 -0.3389 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6002 6.1870 0.3959 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7379 5.6944 0.0349 N 0 0 0 0 0 0 0 0 0 0 0 0 8.8120 7.8139 1.0279 S 0 0 0 0 0 0 0 0 0 0 0 0 10.5475 7.7131 0.7420 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8329 6.4586 0.1913 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1762 6.1540 -0.1214 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1633 7.0623 0.1101 C 0 0 0 0 0 0 0 0 0 0 0 0 12.8718 8.3042 0.6565 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5715 8.6303 0.9702 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4048 -2.7598 -0.7256 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3372 -4.2747 -0.5224 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6599 -4.8620 -0.7739 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.5844 -6.3289 -0.8217 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9909 -6.9038 -1.0054 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.5782 -6.3689 -2.2418 N 0 0 0 0 0 0 0 0 0 0 0 0 -5.6537 -4.9021 -2.1940 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.2473 -4.3272 -2.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.9010 -6.9563 -2.4933 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3826 3.5784 -0.6483 F 0 0 0 0 0 0 0 0 0 0 0 0 -1.0887 1.9918 -0.9943 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.0243 3.4105 -1.1525 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1984 -1.7697 0.0344 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1893 3.1563 -0.5728 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5328 -0.3828 0.9253 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3022 -2.5755 -1.1564 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7224 -2.3640 0.5602 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8377 4.0112 -0.1905 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0173 5.9451 0.9331 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1701 7.1146 1.1157 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9932 2.5405 -0.7448 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4223 5.1925 -0.5473 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1854 6.8133 -0.1341 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6649 9.0152 0.8348 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3453 9.5969 1.3955 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1298 -2.3323 -0.0330 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7096 -2.5438 -1.7496 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6122 -4.7022 -1.2151 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0324 -4.4907 0.5016 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9549 -6.6335 -1.6578 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1580 -6.7016 0.1096 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9340 -7.9903 -1.0702 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6128 -6.6219 -0.1558 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.0802 -4.5294 -3.1253 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.2832 -4.5975 -1.3579 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3041 -3.2406 -1.9455 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.6253 -4.6091 -2.8599 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.5659 -6.7237 -1.6614 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.3129 -6.5432 -3.4140 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.8057 -8.0377 -2.5909 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0042 3.7885 -1.4441 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7242 3.8680 -0.2097 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2952 3.6573 -1.9243 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 39 1 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 13 1 0 0 0 0 11 12 1 0 0 0 0 12 29 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 13 46 1 0 0 0 0 14 19 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 15 47 1 0 0 0 0 16 17 2 0 0 0 0 16 48 1 0 0 0 0 17 20 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 38 1 0 0 0 0 19 49 1 0 0 0 0 20 21 2 0 0 0 0 20 22 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 50 1 0 0 0 0 26 27 1 0 0 0 0 26 51 1 0 0 0 0 27 28 2 0 0 0 0 27 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 32 1 0 0 0 0 31 36 1 0 0 0 0 32 33 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 33 34 1 0 0 0 0 33 60 1 0 0 0 0 33 61 1 0 0 0 0 34 35 1 0 0 0 0 34 37 1 0 0 0 0 35 36 1 0 0 0 0 35 62 1 0 0 0 0 35 63 1 0 0 0 0 36 64 1 0 0 0 0 36 65 1 0 0 0 0 37 66 1 0 0 0 0 37 67 1 0 0 0 0 37 68 1 0 0 0 0 39 40 1 0 0 0 0 40 69 1 0 0 0 0 40 70 1 0 0 0 0 40 71 1 0 0 0 0 M END > 691754 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 14 > 2009 > 691754 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 14 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 57 61 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8410 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3465 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6789 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -0.9593 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1704 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0935 -1.5673 -0.7685 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6094 -3.2092 0.6658 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0263 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0372 -3.2646 0.3601 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2898 -2.2147 -0.5431 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5821 -2.0169 -1.0189 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6024 -2.8444 -0.6065 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3563 -3.8843 0.2871 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0822 -4.0984 0.7716 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3760 -4.6919 0.6836 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6701 -4.4152 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6803 -5.4202 0.7012 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0658 -5.1240 0.1236 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0358 -6.0889 0.6585 N 0 0 0 0 0 0 0 0 0 0 0 0 14.3200 -5.9899 -0.0468 C 0 0 0 0 0 0 0 0 0 0 0 0 15.2548 -7.1020 0.4344 C 0 0 0 0 0 0 0 0 0 0 0 0 15.4685 -6.9647 1.9444 C 0 0 0 0 0 0 0 0 0 0 0 0 14.1115 -7.0225 2.6514 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2100 -5.9127 2.1059 C 0 0 0 0 0 0 0 0 0 0 0 0 16.2949 -8.0339 2.4089 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0009 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4432 -3.0501 -0.0017 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0252 -0.6586 0.0188 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9745 -0.8022 -1.3527 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0677 -3.8688 1.3275 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7850 -1.2142 -1.7123 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6034 -2.6859 -0.9799 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8929 -4.9051 1.4642 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6362 -4.4983 -0.9421 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9712 -3.4052 0.4222 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7142 -5.3372 1.7875 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3792 -6.4302 0.4232 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0319 -5.2070 -0.9627 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3670 -4.1140 0.4016 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1544 -6.0934 -1.1192 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7734 -5.0202 0.1586 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8082 -8.0723 0.2168 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2133 -7.0188 -0.0779 H 0 0 0 0 0 0 0 0 0 0 0 0 15.9506 -6.0109 2.1588 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6470 -7.9915 2.4687 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2533 -6.8825 3.7230 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6685 -4.9434 2.3012 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2380 -5.9601 2.5970 H 0 0 0 0 0 0 0 0 0 0 0 0 16.4721 -8.0098 3.3592 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 31 1 0 0 0 0 1 32 1 0 0 0 0 2 3 1 0 0 0 0 2 33 1 0 0 0 0 3 5 1 0 0 0 0 3 13 2 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 6 10 1 0 0 0 0 7 8 1 0 0 0 0 7 34 1 0 0 0 0 8 9 2 0 0 0 0 8 35 1 0 0 0 0 9 36 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 37 1 0 0 0 0 12 14 1 0 0 0 0 12 38 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 39 1 0 0 0 0 17 18 1 0 0 0 0 17 40 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 41 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 21 43 1 0 0 0 0 22 23 1 0 0 0 0 22 44 1 0 0 0 0 22 45 1 0 0 0 0 23 24 1 0 0 0 0 23 46 1 0 0 0 0 23 47 1 0 0 0 0 24 25 1 0 0 0 0 24 29 1 0 0 0 0 25 26 1 0 0 0 0 25 48 1 0 0 0 0 25 49 1 0 0 0 0 26 27 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 30 1 0 0 0 0 27 52 1 0 0 0 0 28 29 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 30 57 1 0 0 0 0 M END > 592609 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12b > 2008 > 592609 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12b > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 68 73 0 0 0 999 V2000 -0.2411 1.3559 0.0793 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5228 2.1252 -0.7994 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3737 1.5275 -1.7064 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1612 -0.0197 0.0594 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6990 -0.6494 -0.8563 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4742 0.1330 -1.7480 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2887 -0.4925 -2.6128 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3622 -1.8026 -2.6284 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6577 -2.5720 -1.8151 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8221 -2.0551 -0.9216 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0932 -2.8694 -0.0800 N 0 0 0 0 0 0 0 0 0 0 0 0 0.1372 -4.2605 -0.2397 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3517 -4.9308 -0.1680 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3947 -6.3040 -0.3253 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2311 -7.0142 -0.5542 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9073 -0.7605 0.9176 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4271 3.4792 -0.7618 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2334 4.2125 -1.6860 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6986 -0.0481 1.8707 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8579 -0.9334 2.3382 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6534 -0.1920 3.4158 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7839 0.1504 4.4969 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7078 1.0155 4.1286 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8341 0.3227 3.0796 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0361 -4.9734 -0.4647 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9861 -6.3534 -0.6274 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2531 -6.8139 -0.8441 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.0241 -5.6569 -1.2185 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3348 -4.5662 -0.5793 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9924 5.7113 -1.4956 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8556 6.4965 -2.4852 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6242 7.9356 -2.3023 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6045 8.7296 -3.0656 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8079 9.6584 -4.0057 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4199 9.7448 -3.3179 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2652 8.3141 -2.7447 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8164 -4.0441 0.1187 Cl 0 0 0 0 0 0 0 0 0 0 0 0 -0.8977 1.8434 0.7846 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9594 2.1338 -2.3815 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0272 -2.2736 -3.3370 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4498 -2.4789 0.6225 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3402 -6.8230 -0.2695 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2699 -8.0866 -0.6768 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2851 3.9882 -1.5083 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9683 3.9284 -2.7044 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0939 0.8581 1.4117 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.5094 -1.1566 1.4933 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4637 -1.8621 2.7507 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0811 0.7164 2.9916 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4542 -0.8341 3.7828 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1100 1.9397 3.7137 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1069 1.2434 5.0090 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3990 -0.5807 3.5070 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0382 0.9978 2.7650 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0225 -5.5294 -2.3010 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0441 -5.7383 -0.8428 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0594 5.9357 -1.6733 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2574 5.9955 -0.4772 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9074 6.2721 -2.3075 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5905 6.2124 -3.5036 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2115 9.3247 -2.3832 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2423 8.0676 -3.6514 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2730 10.6427 -4.0600 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7192 9.2176 -4.9987 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4253 10.4869 -2.5195 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3632 9.9611 -4.0446 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.0860 7.6313 -3.5183 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4223 8.3165 -1.8988 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 2 0 0 0 0 1 2 1 0 0 0 0 1 38 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 3 6 1 0 0 0 0 3 39 1 0 0 0 0 4 5 1 0 0 0 0 4 16 1 0 0 0 0 5 10 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 40 1 0 0 0 0 9 10 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 41 1 0 0 0 0 12 13 2 0 0 0 0 12 25 1 0 0 0 0 13 14 1 0 0 0 0 13 37 1 0 0 0 0 14 15 2 0 0 0 0 14 42 1 0 0 0 0 15 26 1 0 0 0 0 15 43 1 0 0 0 0 16 19 1 0 0 0 0 17 18 1 0 0 0 0 18 30 1 0 0 0 0 18 44 1 0 0 0 0 18 45 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 19 46 1 0 0 0 0 20 21 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 21 22 1 0 0 0 0 21 49 1 0 0 0 0 21 50 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 51 1 0 0 0 0 23 52 1 0 0 0 0 24 53 1 0 0 0 0 24 54 1 0 0 0 0 25 26 2 0 0 0 0 25 29 1 0 0 0 0 26 27 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 30 31 1 0 0 0 0 30 57 1 0 0 0 0 30 58 1 0 0 0 0 31 32 1 0 0 0 0 31 59 1 0 0 0 0 31 60 1 0 0 0 0 32 33 1 0 0 0 0 32 36 1 0 0 0 0 33 34 1 0 0 0 0 33 61 1 0 0 0 0 33 62 1 0 0 0 0 34 35 1 0 0 0 0 34 63 1 0 0 0 0 34 64 1 0 0 0 0 35 36 1 0 0 0 0 35 65 1 0 0 0 0 35 66 1 0 0 0 0 36 67 1 0 0 0 0 36 68 1 0 0 0 0 M END > 461435 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 17064066 > J. Med. Chem.|2006|49|22|6465 > 15 > 2006 > 461435 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 17064066 > J. Med. Chem.|2006|49|22|6465 > 15 > 2006 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 55 60 0 0 0 0 0 0 0 0999 V2000 -1.0585 -0.6730 2.4159 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3276 -0.9471 3.5598 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9034 -1.5665 3.4473 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3933 -1.9008 2.2690 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7350 -1.6610 1.1476 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5184 -1.0366 1.1802 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2766 -2.0217 -0.0412 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5380 -2.5275 -0.0404 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5895 -1.7454 -0.4258 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8898 -2.2416 -0.4270 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1512 -3.5376 -0.0391 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7651 -3.8588 0.3637 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0860 -4.3708 0.3646 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3110 -5.6963 0.7672 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2594 -6.4720 1.1510 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9604 -5.9690 1.1502 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7054 -4.6878 0.7657 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2586 -0.7664 -0.0743 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5095 -0.1432 -0.0404 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1603 0.0935 -1.2376 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5846 -0.2739 -2.3716 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.3974 -0.8633 -2.3746 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7401 -1.1087 -1.2524 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4614 -4.0237 -0.0458 N 0 0 0 0 0 0 0 0 0 0 0 0 7.5119 -3.1701 -0.3063 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8172 -3.5493 -0.4355 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4055 -1.8729 -0.4727 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6269 -1.3437 -0.7116 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5525 -2.4057 -0.6921 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8908 -2.1340 -0.9141 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2894 -0.8958 -1.1365 N 0 0 0 0 0 0 0 0 0 0 0 0 10.4482 0.1242 -1.1584 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1083 -0.0522 -0.9566 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8307 -1.2321 -3.5823 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.5423 -0.9699 -4.8358 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.0244 -0.1939 2.4782 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7156 -0.6790 4.5314 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4737 -1.7800 4.3392 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4090 -0.7264 -0.7347 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7040 -1.6030 -0.7362 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3130 -6.0992 0.7723 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4351 -7.4918 1.4600 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1435 -6.6046 1.4586 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6933 -4.3110 0.7704 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9573 0.1464 0.8988 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.1281 0.5728 -1.2472 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6317 -4.9618 0.1328 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1643 -4.4520 -0.3612 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6118 -2.9380 -0.9048 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8277 1.1179 -1.3452 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4338 0.7909 -0.9775 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0375 -1.6642 -3.5988 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.7110 0.1019 -4.9404 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9448 -1.3272 -5.6744 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5006 -1.4891 -4.8250 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 36 1 0 0 0 0 2 3 1 0 0 0 0 2 37 1 0 0 0 0 3 4 2 0 0 0 0 3 38 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 39 1 0 0 0 0 10 11 2 0 0 0 0 10 40 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 44 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 20 21 2 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 34 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 25 27 2 0 0 0 0 26 29 1 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 28 29 2 0 0 0 0 28 33 1 0 0 0 0 29 30 1 0 0 0 0 30 31 2 0 0 0 0 30 49 1 0 0 0 0 31 32 1 0 0 0 0 32 33 2 0 0 0 0 32 50 1 0 0 0 0 33 51 1 0 0 0 0 34 35 1 0 0 0 0 34 52 1 0 0 0 0 35 53 1 0 0 0 0 35 54 1 0 0 0 0 35 55 1 0 0 0 0 M END > 731955 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 6 > 2010 > 731955 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 6 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 47 51 0 0 0 0 0 0 0 0999 V2000 0.1298 1.3564 0.2321 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2199 2.1243 -0.1643 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3501 1.5110 -0.6950 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3929 0.1408 -0.8291 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3002 -0.6328 -0.4315 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1668 -0.0141 0.1006 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3429 -2.1027 -0.5744 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3885 -2.9043 -0.2379 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6976 -3.0087 -1.2339 S 0 0 0 0 0 0 0 0 0 0 0 0 1.8216 -4.5183 -0.9939 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5737 -4.2212 -0.4342 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3064 -5.2899 -0.1539 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0566 -6.5737 -0.4235 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2960 -6.8598 -0.9786 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1752 -5.8392 -1.2629 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1795 3.5117 -0.0298 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.0370 4.1844 -0.1151 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0775 3.6847 -0.9012 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.2674 4.3771 -0.9618 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4338 5.5010 -0.2890 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.4728 6.0105 0.4688 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2478 5.3684 0.5856 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6964 7.1976 1.1585 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.8861 7.9093 0.9601 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9827 7.4854 0.1920 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.9286 8.4502 0.2515 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.4539 9.4483 1.0261 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.1735 9.0864 1.4641 N 0 0 0 0 0 0 0 0 0 0 0 0 -6.2737 8.4169 -0.4271 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7446 1.8351 0.6476 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1946 2.1097 -1.0026 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2705 -0.3348 -1.2415 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6795 -0.6098 0.4092 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2752 -5.0867 0.2781 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6279 -7.3793 -0.2025 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5710 -7.8832 -1.1870 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1394 -6.0624 -1.6952 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9987 4.0082 0.1231 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9510 2.7665 -1.4554 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0751 3.9952 -1.5685 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5332 5.7859 1.2038 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0283 7.5325 1.7769 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0573 6.5544 -0.3502 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.9194 10.2709 1.2442 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.0052 7.9585 0.2384 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5859 9.4338 -0.6650 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.2030 7.8343 -1.3456 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 30 1 0 0 0 0 2 16 1 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 3 31 1 0 0 0 0 4 5 1 0 0 0 0 4 32 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 33 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 11 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 34 1 0 0 0 0 13 14 1 0 0 0 0 13 35 1 0 0 0 0 14 15 2 0 0 0 0 14 36 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 38 1 0 0 0 0 17 18 2 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 18 39 1 0 0 0 0 19 20 2 0 0 0 0 19 40 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 41 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 28 2 0 0 0 0 25 26 2 0 0 0 0 25 43 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 27 44 1 0 0 0 0 29 45 1 0 0 0 0 29 46 1 0 0 0 0 29 47 1 0 0 0 0 M END > 557427 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "3, Table 2" > 2009 > 557427 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19211246 > Bioorg. Med. Chem. Lett.|2009|19|5|1349 > "3, Table 2" > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 51 53 0 0 0 0 0 0 0 0999 V2000 0.0711 1.5143 0.3024 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0289 6.4489 1.2135 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2132 5.8431 2.4387 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2861 6.6105 3.5854 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1178 7.9813 3.5147 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1238 8.5899 2.2956 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1923 7.8289 1.1436 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2281 9.1392 5.2571 I 0 0 0 0 0 0 0 0 0 0 0 0 -0.4282 8.4229 -0.0467 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.1027 5.6745 0.0509 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.0458 4.2881 0.1345 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1841 3.6228 0.0027 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2285 2.2272 0.0891 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1459 2.1726 0.4275 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2065 3.5525 0.3444 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3939 4.1850 0.4676 F 0 0 0 0 0 0 0 0 0 0 0 0 -2.2764 1.4615 0.6311 F 0 0 0 0 0 0 0 0 0 0 0 0 2.4193 4.3896 -0.2257 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6106 3.7593 -0.2423 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3652 5.5914 -0.3993 O 0 0 0 0 0 0 0 0 0 0 0 0 0.1229 0.0110 0.3944 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0253 -0.3991 1.7972 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0206 -1.8617 1.9257 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1343 -2.2437 3.3753 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3932 -2.4685 3.9001 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5353 -2.8188 5.2297 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4184 -2.9449 6.0344 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8406 -2.7210 5.5094 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9830 -2.3749 4.1786 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5996 -3.3903 7.7296 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.5255 -5.2028 7.7317 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5503 -2.8435 8.3604 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.9047 -2.9441 8.0716 O 0 0 0 0 0 0 0 0 0 0 0 0 0.3442 4.7726 2.4957 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4745 6.1390 4.5386 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2552 9.6607 2.2436 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1936 6.1049 -0.8136 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1711 1.7095 -0.0111 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3939 4.3050 -0.3959 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6865 -0.4173 -0.1968 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0798 -0.3437 0.0113 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6756 0.0370 2.3774 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7895 -2.3031 1.3451 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9767 -2.2294 1.5533 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2658 -2.3700 3.2714 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5189 -2.9937 5.6400 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7132 -2.8191 6.1382 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9666 -2.2000 3.7684 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4324 -5.5278 7.3257 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6306 -5.5695 8.7527 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.3339 -5.6002 7.1179 H 0 0 0 0 0 0 0 0 0 0 0 0 1 21 1 0 0 0 0 1 13 2 0 0 0 0 1 14 1 0 0 0 0 2 10 1 0 0 0 0 2 7 1 0 0 0 0 2 3 2 0 0 0 0 3 4 1 0 0 0 0 3 34 1 0 0 0 0 4 5 2 0 0 0 0 4 35 1 0 0 0 0 5 6 1 0 0 0 0 5 8 1 0 0 0 0 6 7 2 0 0 0 0 6 36 1 0 0 0 0 7 9 1 0 0 0 0 10 11 1 0 0 0 0 10 37 1 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 12 18 1 0 0 0 0 12 13 1 0 0 0 0 13 38 1 0 0 0 0 14 17 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 18 19 1 0 0 0 0 18 20 2 0 0 0 0 19 39 1 0 0 0 0 21 22 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 2 0 0 0 0 24 29 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 26 27 2 0 0 0 0 26 46 1 0 0 0 0 27 28 1 0 0 0 0 27 30 1 0 0 0 0 28 29 2 0 0 0 0 28 47 1 0 0 0 0 29 48 1 0 0 0 0 30 31 1 0 0 0 0 30 32 2 0 0 0 0 30 33 2 0 0 0 0 31 49 1 0 0 0 0 31 50 1 0 0 0 0 31 51 1 0 0 0 0 M END > 573511 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19019675 > Bioorg. Med. Chem. Lett.|2009|19|1|226 > 6a > 2009 > 573511 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 19019675 > Bioorg. Med. Chem. Lett.|2009|19|1|226 > 6a > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 74 79 0 0 0 0 0 0 0 0999 V2000 -0.0930 1.3127 -0.6480 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2906 2.0234 -0.4881 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4512 1.3744 -0.1289 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0514 -0.0384 -0.4510 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2158 -0.7210 -0.0797 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4316 -0.0102 0.0781 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5361 -0.6903 0.4232 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.4869 -1.9878 0.6100 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3750 -2.6928 0.4742 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2275 -2.1196 0.1359 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3067 3.3669 -0.6891 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5573 4.0347 -0.5103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0387 1.9748 -1.0087 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2260 1.1944 -1.1617 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0753 -2.8677 -0.0027 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1306 -4.2583 0.0941 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2721 -4.9377 -0.3178 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3276 -6.3113 -0.2287 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2363 -7.0215 0.2757 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9088 -6.3363 0.6885 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9582 -4.9630 0.5971 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2927 -8.4947 0.3730 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3011 -9.2189 0.0193 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0067 -9.5117 0.9799 S 0 0 0 0 0 0 0 0 0 0 0 0 0.0311 -10.9506 0.6949 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2006 -10.5516 0.1634 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1518 -11.5492 -0.1454 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8712 -12.8632 0.0715 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6474 -13.2505 0.5993 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3004 -12.3012 0.9086 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3796 5.5306 -0.7780 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.7186 6.2456 -0.5865 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5479 7.6818 -0.8435 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.8480 8.3644 -0.9027 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6243 9.8666 -1.0920 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8570 10.0935 -2.3246 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5569 9.4109 -2.2655 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7806 7.9087 -2.0762 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6863 11.5297 -2.5817 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1932 -4.2230 1.0423 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3696 1.9296 -0.0074 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8754 -0.5775 -0.5815 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3942 -2.5037 0.8874 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2903 3.6257 -1.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9049 3.8874 0.5123 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0527 1.8435 -1.4505 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4622 0.7034 -0.2176 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0687 0.4411 -1.9336 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7727 -2.4264 -0.1674 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1161 -4.3878 -0.7075 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2145 -6.8383 -0.5483 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7543 -6.8828 1.0794 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1097 -11.2669 -0.5566 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6097 -13.6134 -0.1698 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4385 -14.2968 0.7669 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2526 -12.6032 1.3194 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6466 5.9395 -0.0826 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0319 5.6779 -1.8005 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.4515 5.8366 -1.2819 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0662 6.0983 0.4360 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.4257 7.9743 -1.7406 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.3918 8.1919 0.0260 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.5876 10.3713 -1.1652 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0701 10.2619 -0.2407 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0131 9.5834 -3.1942 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9792 9.8010 -1.4275 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8173 7.4040 -2.0030 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3349 7.5135 -2.9275 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1525 11.9870 -1.7486 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1152 11.6692 -3.4995 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.6646 11.9986 -2.6876 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8791 -4.1217 0.2012 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9133 -3.2336 1.4040 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6805 -4.7784 1.8436 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 13 1 0 0 0 0 1 2 2 0 0 0 0 2 11 1 0 0 0 0 2 3 1 0 0 0 0 3 6 2 0 0 0 0 3 41 1 0 0 0 0 4 5 2 0 0 0 0 4 42 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 43 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 31 1 0 0 0 0 12 44 1 0 0 0 0 12 45 1 0 0 0 0 13 14 1 0 0 0 0 14 46 1 0 0 0 0 14 47 1 0 0 0 0 14 48 1 0 0 0 0 15 16 1 0 0 0 0 15 49 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 51 1 0 0 0 0 19 20 1 0 0 0 0 19 22 1 0 0 0 0 20 21 2 0 0 0 0 20 52 1 0 0 0 0 21 40 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 33 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 38 1 0 0 0 0 34 35 1 0 0 0 0 34 61 1 0 0 0 0 34 62 1 0 0 0 0 35 36 1 0 0 0 0 35 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 39 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 69 1 0 0 0 0 39 70 1 0 0 0 0 39 71 1 0 0 0 0 40 72 1 0 0 0 0 40 73 1 0 0 0 0 40 74 1 0 0 0 0 M END > 691794 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 6 > 2009 > 691794 > Vascular endothelial growth factor receptor 3 > Homo sapiens > 19692247 > Bioorg. Med. Chem.|2009|17|18|6728 > 6 > 2009 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 56 60 0 0 0 999 V2000 -0.2495 1.3955 0.5290 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0122 0.0698 0.1550 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2648 -0.3645 -0.1195 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7746 2.2870 0.6301 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0868 1.8778 0.3572 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3380 0.5366 -0.0222 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6556 0.1286 -0.2966 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6819 1.0192 -0.1975 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4554 2.3389 0.1737 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1726 2.7846 0.4540 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9398 4.1870 0.8464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9847 5.0198 1.0226 N 0 0 0 0 0 0 0 0 0 0 0 0 1.8051 4.5919 1.0111 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7535 6.4129 1.4125 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0526 -0.7992 0.0619 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.8749 -0.6952 -1.0113 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.5387 -0.4666 -3.2121 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4604 0.2768 -3.1239 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6000 0.1927 -2.0370 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.8624 -1.3491 -2.2599 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0350 -1.4937 -1.1197 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.3766 -2.4206 -0.1228 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.5047 -3.1758 -0.2609 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.3263 -3.0349 -1.3890 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.0172 -2.1415 -2.3733 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.4445 -3.7984 -1.5036 O 0 0 0 0 0 0 0 0 0 0 0 0 -7.2415 -3.6100 -2.6746 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.8356 -4.0743 0.7046 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.9584 -4.1713 1.8286 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9435 7.0527 2.1470 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6526 8.3300 1.3417 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0120 7.4205 0.2800 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2592 1.7181 0.7362 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4404 -1.3905 -0.4071 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5758 3.3083 0.9195 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8543 -0.8927 -0.5862 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6893 0.6935 -0.4109 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2870 3.0243 0.2454 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8899 4.6967 0.8913 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7990 6.5580 1.9184 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2385 0.9760 -3.9164 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7204 0.8176 -1.9921 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7495 -2.5360 0.7489 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.6588 -2.0434 -3.2366 H 0 0 0 0 0 0 0 0 0 0 0 0 -7.5865 -2.5770 -2.7171 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6445 -3.8303 -3.5597 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.1012 -4.2792 -2.6405 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9634 -4.4592 1.4892 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9054 -3.2062 2.3324 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.3375 -4.9225 2.5215 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7845 7.1668 3.2193 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9027 6.5940 1.9067 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9437 9.0005 1.8275 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5505 8.8413 0.9945 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7165 7.0624 -0.4707 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1010 7.8317 -0.1550 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 33 1 0 0 0 0 2 3 1 0 0 0 0 2 15 1 0 0 0 0 3 6 2 0 0 0 0 3 34 1 0 0 0 0 4 5 2 0 0 0 0 4 35 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 36 1 0 0 0 0 8 9 1 0 0 0 0 8 37 1 0 0 0 0 9 10 2 0 0 0 0 9 38 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 13 2 0 0 0 0 12 14 1 0 0 0 0 12 39 1 0 0 0 0 14 30 1 0 0 0 0 14 32 1 0 0 0 0 14 40 1 0 0 0 0 15 16 1 0 0 0 0 16 21 2 0 0 0 0 16 19 1 0 0 0 0 17 20 2 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 18 41 1 0 0 0 0 19 42 1 0 0 0 0 20 21 1 0 0 0 0 20 25 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 28 1 0 0 0 0 24 25 2 0 0 0 0 24 26 1 0 0 0 0 25 44 1 0 0 0 0 26 27 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 29 1 0 0 0 0 29 48 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 31 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 32 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 M END > 540568 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 10 > 2008 > 540568 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18324761 > J. Med. Chem.|2008|51|6|1649 > 74 > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 56 60 0 0 0 0 0 0 0 0999 V2000 -0.0184 1.5043 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3851 1.9328 -0.0008 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1691 0.8410 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3465 -0.3797 -0.0128 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6789 -1.7489 -0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 -2.7027 -0.0196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6599 -2.3066 -0.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9880 -0.9593 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0933 -2.1704 -0.0400 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0935 -1.5673 -0.7685 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6094 -3.2092 0.6658 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3849 0.8591 -0.0263 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0372 -3.2646 0.3601 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2898 -2.2147 -0.5431 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5821 -2.0169 -1.0189 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6024 -2.8444 -0.6065 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3563 -3.8843 0.2871 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0822 -4.0984 0.7716 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3760 -4.6919 0.6836 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6701 -4.4152 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6803 -5.4202 0.7012 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0658 -5.1240 0.1236 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0358 -6.0889 0.6585 N 0 0 0 0 0 0 0 0 0 0 0 0 14.3200 -5.9899 -0.0468 C 0 0 0 0 0 0 0 0 0 0 0 0 15.3462 -6.9023 0.6290 C 0 0 0 0 0 0 0 0 0 0 0 0 14.8363 -8.3457 0.5994 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4753 -8.4123 1.2978 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5033 -7.4563 0.6027 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5139 1.8675 0.9107 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5310 1.8771 -0.8765 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6956 2.8517 0.0009 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9089 -3.7540 -0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4432 -3.0501 -0.0017 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0252 -0.6586 0.0188 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9745 -0.8022 -1.3527 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0677 -3.8688 1.3275 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7850 -1.2142 -1.7123 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6034 -2.6859 -0.9799 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8929 -4.9051 1.4642 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6362 -4.4983 -0.9421 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9712 -3.4052 0.4222 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7142 -5.3372 1.7875 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3792 -6.4302 0.4232 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0319 -5.2070 -0.9627 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3670 -4.1140 0.4016 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1891 -6.2967 -1.0845 H 0 0 0 0 0 0 0 0 0 0 0 0 14.6735 -4.9594 -0.0147 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2949 -6.8405 0.0958 H 0 0 0 0 0 0 0 0 0 0 0 0 15.4880 -6.5875 1.6629 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7315 -8.6740 -0.4347 H 0 0 0 0 0 0 0 0 0 0 0 0 15.5439 -8.9927 1.1180 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0873 -9.4295 1.2426 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5876 -8.1213 2.3423 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5374 -7.4907 1.1065 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3809 -7.7562 -0.4381 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 1 0 0 0 0 1 30 1 0 0 0 0 1 31 1 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 13 2 0 0 0 0 3 5 1 0 0 0 0 4 9 1 0 0 0 0 4 5 2 0 0 0 0 5 6 1 0 0 0 0 6 7 2 0 0 0 0 6 10 1 0 0 0 0 7 8 1 0 0 0 0 7 33 1 0 0 0 0 8 9 2 0 0 0 0 8 34 1 0 0 0 0 9 35 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 15 1 0 0 0 0 11 36 1 0 0 0 0 12 14 1 0 0 0 0 12 37 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 38 1 0 0 0 0 17 18 1 0 0 0 0 17 39 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 19 40 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 41 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 29 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 27 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 28 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 28 29 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 M END > 592662 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12e > 2008 > 592662 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 18718756 > Bioorg. Med. Chem. Lett.|2008|18|18|5130 > 12e > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 53 56 0 0 0 0 0 0 0 0999 V2000 -1.1968 -0.9978 2.4052 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5343 -1.4331 3.5407 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7028 -2.0377 3.4157 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2628 -2.2066 2.2334 N 0 0 0 0 0 0 0 0 0 0 0 0 0.6715 -1.8088 1.1196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5835 -1.1884 1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2838 -2.0027 -0.0739 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5433 -2.5131 -0.0693 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6186 -1.6843 -0.2198 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9167 -2.1863 -0.2180 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1519 -3.5346 -0.0637 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7436 -3.8986 0.0966 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0621 -4.4169 0.0945 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2603 -5.7971 0.2550 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1852 -6.6194 0.4055 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8883 -6.1108 0.4027 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6595 -4.7762 0.2589 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2481 -0.7407 -0.0811 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5007 -0.1216 -0.0344 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.0796 0.2845 -1.2231 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4361 0.0768 -2.3612 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2491 -0.5127 -2.3762 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6592 -0.9168 -1.2625 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4617 -4.0259 -0.0642 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4840 -3.2197 0.2844 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6100 -0.7109 -3.5879 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.2460 -0.2708 -4.8321 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7542 -3.6566 0.1751 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2602 -2.0982 0.6974 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8654 -2.7803 0.5540 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1905 -3.5134 0.3355 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.1659 -0.5266 2.4766 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9799 -1.3010 4.5156 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2196 -2.3772 4.3012 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4590 -0.6232 -0.3424 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7501 -1.5101 -0.3395 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2603 -6.2050 0.2587 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3402 -7.6811 0.5284 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0525 -6.7840 0.5235 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6487 -4.3958 0.2589 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.0047 0.0356 0.9078 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.0466 0.7656 -1.2228 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6342 -4.9468 -0.3154 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2590 -1.1411 -3.6132 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.2017 -0.7812 -4.9519 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4114 0.8059 -4.7946 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5983 -0.5098 -5.6755 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9327 -4.5513 -0.1544 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8431 -1.8795 -0.0593 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7705 -2.5068 1.6048 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0172 -2.8614 0.6174 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2127 -4.4142 0.9488 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2854 -3.7869 -0.7154 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 1 32 1 0 0 0 0 2 3 1 0 0 0 0 2 33 1 0 0 0 0 3 4 2 0 0 0 0 3 34 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 18 1 0 0 0 0 7 8 1 0 0 0 0 8 9 2 0 0 0 0 8 12 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 2 0 0 0 0 10 36 1 0 0 0 0 11 13 1 0 0 0 0 11 24 1 0 0 0 0 12 17 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 14 37 1 0 0 0 0 15 16 2 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 16 39 1 0 0 0 0 17 40 1 0 0 0 0 18 19 2 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 41 1 0 0 0 0 20 21 2 0 0 0 0 20 42 1 0 0 0 0 21 22 1 0 0 0 0 22 23 2 0 0 0 0 22 26 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 25 28 1 0 0 0 0 25 29 2 0 0 0 0 26 27 1 0 0 0 0 26 44 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 30 1 0 0 0 0 28 48 1 0 0 0 0 30 31 1 0 0 0 0 30 49 1 0 0 0 0 30 50 1 0 0 0 0 31 51 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 M END > 732022 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 12 > 2010 > 732022 > Vascular endothelial growth factor receptor 2 > Homo sapiens > 20459125 > J. Med. Chem.|2010|53|11|4502 > 12 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 56 59 0 0 0 999 V2000 0.2207 1.0332 0.1701 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2352 0.5695 1.4124 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4105 0.9081 2.5665 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3226 1.8346 0.0880 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0058 2.1977 1.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5476 1.7312 2.5146 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1976 2.0762 3.6325 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2613 2.8441 3.6010 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7709 3.3411 2.4080 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1502 3.0252 1.2123 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4382 0.6765 -0.9646 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.3347 -0.2271 1.4683 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7512 -0.6681 2.7621 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0754 1.1813 -2.1989 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6255 3.4956 0.0327 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7909 4.1940 0.0475 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7650 5.5528 -0.0933 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1842 4.1876 0.2310 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0012 3.5139 0.2122 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1937 5.5817 0.0833 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9696 6.2756 -0.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9794 7.6742 -0.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1597 8.3553 -0.2037 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3701 7.6922 -0.0468 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4077 6.3130 0.0969 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6964 5.6156 0.2631 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8512 6.3063 0.1867 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7171 4.4174 0.4690 O 0 0 0 0 0 0 0 0 0 0 0 0 12.1314 5.6135 0.3518 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2765 6.6198 0.2210 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2123 7.5570 1.2978 O 0 0 0 0 0 0 0 0 0 0 0 0 14.2432 8.5462 1.2696 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0481 0.5444 3.5166 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6672 2.1867 -0.8730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7541 3.0968 4.5282 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6478 3.9716 2.4138 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9493 -1.2428 3.2257 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9843 0.1968 3.3832 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6377 -1.2948 2.6644 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1002 0.8357 -2.3344 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5411 0.8221 -3.0229 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0588 2.2710 -2.1809 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8238 6.0682 -0.2159 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1123 3.6494 0.3550 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9977 2.4400 0.3265 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0498 8.2098 -0.3449 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1538 9.4296 -0.3144 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2912 8.2561 -0.0370 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8347 7.2622 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1680 5.1474 1.3364 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2316 4.8472 -0.4169 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2296 6.0920 0.2550 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1881 7.1495 -0.7275 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2164 8.0584 1.3254 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1749 9.1159 0.3429 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1247 9.2188 2.1191 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 4 1 0 0 0 0 1 11 1 0 0 0 0 2 3 1 0 0 0 0 2 12 1 0 0 0 0 3 6 2 0 0 0 0 3 33 1 0 0 0 0 4 5 2 0 0 0 0 4 34 1 0 0 0 0 5 10 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 35 1 0 0 0 0 9 10 2 0 0 0 0 9 36 1 0 0 0 0 10 15 1 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 14 40 1 0 0 0 0 14 41 1 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 19 1 0 0 0 0 17 21 1 0 0 0 0 17 43 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 18 44 1 0 0 0 0 19 45 1 0 0 0 0 20 21 1 0 0 0 0 20 25 2 0 0 0 0 21 22 2 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 23 24 2 0 0 0 0 23 47 1 0 0 0 0 24 25 1 0 0 0 0 24 48 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 27 49 1 0 0 0 0 29 30 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 31 32 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 M END > 540558 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 20 > 2008 > 540558 > Vascular endothelial growth factor receptor 1 > Homo sapiens > 18324759 > J. Med. Chem.|2008|51|6|1668 > 20 > 2008 $$$$