22 csChFnd70/04170815452D 62 66 0 0 0 0 0 0 0 0999 V2000 11.3278 5.2899 -1.2605 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5342 3.5169 -1.4536 C 0 0 0 0 0 0 0 0 0 0 0 0 12.8845 2.6711 -0.6243 C 0 0 0 0 0 0 0 0 0 0 0 0 14.0384 3.6020 0.4050 C 0 0 0 0 0 0 0 0 0 0 0 0 13.8353 5.3799 0.6007 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4779 6.2268 -0.2327 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2692 8.0217 -0.0379 N 0 0 3 0 0 0 0 0 0 0 0 0 10.6477 8.7589 -0.2178 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8405 9.0230 -0.5544 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5931 10.6783 -0.4260 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7696 11.9706 -0.7380 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5433 12.1536 -0.5219 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0613 8.8602 -0.7759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0321 10.3253 -0.8653 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3323 10.4297 -0.2223 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7424 13.4047 -0.8321 O 0 0 0 0 0 0 0 0 0 0 0 0 13.1382 0.4432 -0.8692 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.7411 14.3249 -2.3366 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6614 16.6361 -4.1260 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8171 14.8497 -5.2089 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8534 13.8842 -3.6936 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7493 16.1740 -5.3834 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6217 15.7283 -2.5638 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4798 18.1332 -4.3897 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4820 18.5629 -3.2440 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5117 19.0187 -5.9003 N 0 0 3 0 0 0 0 0 0 0 0 0 1.3435 20.4988 -6.1609 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1595 7.8668 -0.4219 O 0 0 0 0 0 0 0 0 0 0 0 0 15.3654 2.7692 1.2202 O 0 0 0 0 0 0 0 0 0 0 0 0 16.5019 3.8080 2.2577 C 0 0 0 0 0 0 0 0 0 0 0 0 17.9035 2.6524 3.0653 C 0 0 2 0 0 0 0 0 0 0 0 0 17.0493 1.2254 4.1854 C 0 0 0 0 0 0 0 0 0 0 0 0 18.2947 1.0804 5.7637 C 0 0 0 0 0 0 0 0 0 0 0 0 18.8657 2.9950 6.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 19.0179 3.6932 4.2252 N 0 0 3 0 0 0 0 0 0 0 0 0 18.5297 5.5377 4.1688 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2750 5.9485 -1.9139 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6385 2.7904 -2.2533 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7312 6.1058 1.4006 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2660 8.7473 0.2237 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1139 13.4321 -0.4275 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4805 7.5868 -0.8791 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6452 10.1939 -1.0341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6819 14.5155 -6.2625 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7354 12.8003 -3.5642 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7359 16.1058 -1.5430 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3083 18.6758 -6.8151 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6064 21.4859 -5.1801 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5551 21.0458 -7.4500 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 20.0655 -6.0466 H 0 0 0 0 0 0 0 0 0 0 0 0 17.1133 4.7941 1.4455 H 0 0 0 0 0 0 0 0 0 0 0 0 15.7589 4.4375 3.2861 H 0 0 0 0 0 0 0 0 0 0 0 0 18.6885 2.0626 2.0446 H 0 0 0 0 0 0 0 0 0 0 0 0 15.7559 1.6241 4.6032 H 0 0 0 0 0 0 0 0 0 0 0 0 16.9929 0.0000 3.4777 H 0 0 0 0 0 0 0 0 0 0 0 0 17.6099 0.6051 6.9086 H 0 0 0 0 0 0 0 0 0 0 0 0 19.4048 0.2549 5.4598 H 0 0 0 0 0 0 0 0 0 0 0 0 17.8857 3.7125 6.7369 H 0 0 0 0 0 0 0 0 0 0 0 0 20.1163 3.0560 6.6701 H 0 0 0 0 0 0 0 0 0 0 0 0 17.2206 5.6955 4.6859 H 0 0 0 0 0 0 0 0 0 0 0 0 19.4399 6.2910 4.9499 H 0 0 0 0 0 0 0 0 0 0 0 0 18.5664 5.9949 2.8288 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 37 1 0 0 0 0 2 3 2 0 0 0 0 2 38 1 0 0 0 0 3 4 1 0 0 0 0 3 17 1 0 0 0 0 4 5 2 0 0 0 0 4 29 1 0 0 0 0 5 6 1 0 0 0 0 5 39 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 40 1 0 0 0 0 8 15 2 0 0 0 0 8 28 1 0 0 0 0 9 28 1 0 0 0 0 9 13 1 0 0 0 0 9 10 2 0 0 0 0 10 15 1 0 0 0 0 10 12 1 0 0 0 0 11 12 2 0 0 0 0 11 14 1 0 0 0 0 11 16 1 0 0 0 0 12 41 1 0 0 0 0 13 14 2 0 0 0 0 13 42 1 0 0 0 0 14 43 1 0 0 0 0 16 18 1 0 0 0 0 18 21 1 0 0 0 0 18 23 2 0 0 0 0 19 23 1 0 0 0 0 19 22 2 0 0 0 0 19 24 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 20 44 1 0 0 0 0 21 45 1 0 0 0 0 23 46 1 0 0 0 0 24 26 1 0 0 0 0 24 25 2 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 29 30 1 0 0 0 0 30 31 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 35 1 0 0 0 0 31 32 1 0 0 0 0 31 53 1 0 0 0 0 32 33 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 33 34 1 0 0 0 0 33 56 1 0 0 0 0 33 57 1 0 0 0 0 34 35 1 0 0 0 0 34 58 1 0 0 0 0 34 59 1 0 0 0 0 35 36 1 0 0 0 0 36 60 1 0 0 0 0 36 61 1 0 0 0 0 36 62 1 0 0 0 0 M END > (3) 1 > (3) C26H26ClN5O4 > (3) 507.9755 > (3) FGFR-P1 > (3) 2-aminobenzoxazole, 22 > (3) FGFR-1 Tyrosine Kinase > (3) 4370 > (3) 2007 17696416 Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors. 2007 > (3) 2007 > (3) P > (3) TEST $$$$ 43 csChFnd70/04170815452D 96100 0 0 0 0 0 0 0 0999 V2000 4.4464 13.8123 -0.8177 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1944 16.2969 0.6020 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3801 17.3700 -0.2326 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5937 16.6653 -1.3663 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3470 19.1650 0.0628 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8886 20.0852 0.1871 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8824 20.0635 0.2805 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2897 22.7201 0.4402 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8826 21.8530 0.4271 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3817 19.2282 0.1644 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8338 21.8005 0.3189 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2275 24.5213 0.5790 N 0 0 3 0 0 0 0 0 0 0 0 0 7.1260 25.5078 -0.8644 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2085 24.8328 -2.2893 O 0 0 0 0 0 0 0 0 0 0 0 0 6.9332 27.2418 -0.7274 O 0 0 0 0 0 0 0 0 0 0 0 0 6.8396 28.1597 -2.2337 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1495 29.3903 -4.5427 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2410 28.4571 -3.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3419 28.8070 -2.9912 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2435 29.7395 -4.5219 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6494 30.0283 -5.2987 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0797 28.4938 -2.1444 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6058 27.7622 -2.1887 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2704 25.3119 2.2234 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8485 25.7615 2.9669 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8910 26.5400 4.5849 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7266 25.6517 3.1059 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7732 26.4318 4.7268 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3559 26.8726 5.4685 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4019 27.6380 7.0601 O 0 0 0 0 0 0 0 0 0 0 0 0 9.0754 28.0643 7.7427 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1768 25.2186 2.3766 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6471 25.6054 3.3556 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4790 12.0666 -1.1045 O 0 0 0 0 0 0 0 0 0 0 0 0 5.5574 11.0485 0.0131 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4266 9.1333 -0.5039 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6277 14.8883 -1.6590 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5812 8.0435 0.6927 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6638 3.2753 0.4768 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7699 5.1591 1.1051 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7007 5.5258 0.5234 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5947 3.6419 -0.1048 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4554 6.2045 0.1965 N 0 0 0 0 0 0 0 0 0 0 0 0 6.8172 14.1980 -2.7687 O 0 0 0 0 0 0 0 0 0 0 0 0 7.9914 15.3806 -3.5882 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9090 2.5964 0.8038 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7834 0.7576 0.3074 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2268 14.5197 0.3107 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0651 13.4688 1.1285 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8489 14.2842 2.2704 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2468 16.8468 1.4790 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5113 17.5016 -2.0203 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2443 19.7641 0.1804 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0927 19.3533 0.2604 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0880 22.5650 0.5243 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9053 29.6217 -5.1493 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4126 30.2436 -5.1121 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5752 30.7571 -6.4957 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6344 27.2874 -2.6375 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9507 29.5703 -2.4421 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9108 28.3972 -0.7416 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0823 28.7258 -1.2923 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6500 27.4866 -3.1968 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9026 26.5715 -1.4812 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0455 25.5029 2.2815 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1214 26.8895 5.1621 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5780 26.6969 5.4130 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9266 28.6658 9.0163 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8496 26.8844 7.8651 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7263 28.9673 6.8669 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5039 25.1947 2.6271 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6913 24.9167 4.5923 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5791 26.9999 3.5939 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9015 11.4793 -0.1071 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1292 11.2060 1.3540 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0826 8.7027 -0.3837 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8546 8.9760 -1.8448 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9252 8.4742 0.5726 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1529 8.2010 2.0336 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9392 3.2239 -0.9115 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6123 2.4896 1.1764 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5295 5.2062 2.5002 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0589 5.6772 0.8297 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7523 6.3115 -0.1761 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4254 5.5772 1.9118 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3055 3.1239 0.1706 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8351 3.5949 -1.4999 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2579 16.3203 -4.3530 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7433 16.0607 -2.5992 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8685 14.6624 -4.4373 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7114 0.0000 1.0632 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4716 0.2882 0.5630 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0737 0.6199 -1.0719 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 13.3014 2.8359 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5477 14.9553 3.3034 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0709 15.2178 1.5428 H 0 0 0 0 0 0 0 0 0 0 0 0 1 34 1 0 0 0 0 1 37 2 0 0 0 0 1 48 1 0 0 0 0 2 48 2 0 0 0 0 2 3 1 0 0 0 0 2 51 1 0 0 0 0 3 4 2 0 0 0 0 3 5 1 0 0 0 0 4 37 1 0 0 0 0 4 52 1 0 0 0 0 5 6 1 0 0 0 0 5 53 1 0 0 0 0 6 10 2 0 0 0 0 6 11 1 0 0 0 0 7 10 1 0 0 0 0 7 9 2 0 0 0 0 7 54 1 0 0 0 0 8 11 2 0 0 0 0 8 9 1 0 0 0 0 8 12 1 0 0 0 0 9 55 1 0 0 0 0 12 13 1 0 0 0 0 12 24 1 0 0 0 0 13 15 1 0 0 0 0 13 14 2 0 0 0 0 15 16 1 0 0 0 0 16 18 2 0 0 0 0 16 19 1 0 0 0 0 17 18 1 0 0 0 0 17 21 2 0 0 0 0 17 56 1 0 0 0 0 18 23 1 0 0 0 0 19 20 2 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 20 57 1 0 0 0 0 21 58 1 0 0 0 0 22 59 1 0 0 0 0 22 60 1 0 0 0 0 22 61 1 0 0 0 0 23 62 1 0 0 0 0 23 63 1 0 0 0 0 23 64 1 0 0 0 0 24 25 2 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 65 1 0 0 0 0 26 29 2 0 0 0 0 26 66 1 0 0 0 0 27 28 2 0 0 0 0 27 32 1 0 0 0 0 28 29 1 0 0 0 0 28 67 1 0 0 0 0 29 30 1 0 0 0 0 30 31 1 0 0 0 0 31 68 1 0 0 0 0 31 69 1 0 0 0 0 31 70 1 0 0 0 0 32 33 1 0 0 0 0 33 71 1 0 0 0 0 33 72 1 0 0 0 0 33 73 1 0 0 0 0 34 35 1 0 0 0 0 35 36 1 0 0 0 0 35 74 1 0 0 0 0 35 75 1 0 0 0 0 36 38 1 0 0 0 0 36 76 1 0 0 0 0 36 77 1 0 0 0 0 37 44 1 0 0 0 0 38 43 1 0 0 0 0 38 78 1 0 0 0 0 38 79 1 0 0 0 0 39 40 1 0 0 0 0 39 46 1 0 0 0 0 39 80 1 0 0 0 0 39 81 1 0 0 0 0 40 43 1 0 0 0 0 40 82 1 0 0 0 0 40 83 1 0 0 0 0 41 43 1 0 0 0 0 41 42 1 0 0 0 0 41 84 1 0 0 0 0 41 85 1 0 0 0 0 42 46 1 0 0 0 0 42 86 1 0 0 0 0 42 87 1 0 0 0 0 44 45 1 0 0 0 0 45 88 1 0 0 0 0 45 89 1 0 0 0 0 45 90 1 0 0 0 0 46 47 1 0 0 0 0 47 91 1 0 0 0 0 47 92 1 0 0 0 0 47 93 1 0 0 0 0 48 49 1 0 0 0 0 49 50 1 0 0 0 0 50 94 1 0 0 0 0 50 95 1 0 0 0 0 50 96 1 0 0 0 0 M END > (232) 230 > (232) C37H46N6O7 > (232) 686.8064 > (232) FGFR-P230 > (232) 2-aminopyrimidine carbamate, 43 > (232) FGFR-1 Tyrosine Kinase > (232) 110 > (232) BINDDB > (232) <2007 > (232) P > (232) TRAIN $$$$ 3-substituted indolin-2-one 11a csChFnd70/04170815452D 38 40 0 0 0 0 0 0 0 0999 V2000 1.9309 3.8285 -0.3164 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3059 2.3868 -2.6113 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3905 4.1484 -2.2422 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1888 4.8666 -1.0839 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6080 6.7339 -0.9599 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1006 6.9841 -2.1139 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4985 5.4436 -2.8224 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8469 8.3493 -2.3824 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7747 7.9740 0.0277 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4684 9.6603 0.1527 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5325 11.1867 0.3052 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2016 10.0934 0.1533 N 0 0 3 0 0 0 0 0 0 0 0 0 0.5876 11.3548 0.3685 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3429 11.8405 0.2951 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7324 12.5384 0.3897 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8676 2.0819 -0.6991 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0527 1.3676 -1.8422 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3121 14.4381 0.5611 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0570 14.8886 2.4752 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6367 16.7882 2.6465 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5501 17.6892 1.3688 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3586 17.4792 4.2187 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0111 4.3852 0.5797 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2225 1.8146 -3.5010 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4397 5.2594 -3.6353 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5923 7.6517 0.7039 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1599 9.2843 0.0674 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1522 11.2827 1.7104 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2041 12.5966 -0.1851 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.3066 -0.3743 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5437 12.5588 0.3302 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8929 1.2713 -0.1059 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9956 0.0000 -2.1351 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3752 15.2049 0.0343 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1266 14.7241 -0.1520 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9938 14.1217 3.0019 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2423 14.6023 3.1884 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0933 18.7033 4.2633 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 23 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 24 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 25 1 0 0 0 0 9 10 1 0 0 0 0 9 26 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 27 1 0 0 0 0 13 28 1 0 0 0 0 13 29 1 0 0 0 0 13 30 1 0 0 0 0 14 15 2 0 0 0 0 14 31 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 32 1 0 0 0 0 17 33 1 0 0 0 0 18 19 1 0 0 0 0 18 34 1 0 0 0 0 18 35 1 0 0 0 0 19 20 1 0 0 0 0 19 36 1 0 0 0 0 19 37 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 38 1 0 0 0 0 M END > (239) 237 > (239) C17H16N2O3 > (239) 296.325 > (239) FGFR-P237 > (239) 3-substituted indolin-2-one 11a > (239) FGFR-1 Tyrosine Kinase > (239) 3680 > (239) BINDDB > (239) <2007 > (239) P > (239) TRAIN $$$$ 3-substituted indolin-2-one 11b csChFnd70/04170815452D 41 43 0 0 0 0 0 0 0 0999 V2000 2.4315 5.2465 -0.3176 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8088 3.7978 -2.6153 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8879 5.5588 -2.2397 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6854 6.2758 -1.0818 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1051 8.1401 -0.9575 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5951 8.3862 -2.1089 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9904 6.8484 -2.8148 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3426 9.7470 -2.3772 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2746 9.3789 0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9687 11.0612 0.1515 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0365 12.5854 0.3034 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6989 11.4915 0.1517 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0959 12.7552 0.3673 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8419 13.2348 0.2922 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2354 13.9332 0.3867 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3671 3.4839 -0.7049 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5667 2.7728 -1.8590 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8180 15.8295 0.5560 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5638 16.2811 2.4660 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1465 18.1775 2.6353 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0611 19.0758 1.3593 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8697 18.8687 4.2038 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0397 2.3750 0.0998 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.9951 1.1018 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9804 0.6742 -0.2760 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5138 5.8035 0.5761 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7274 3.2349 -3.5043 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9303 6.6642 -3.6253 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0941 9.0588 0.7018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6545 10.6829 0.0666 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6617 12.6844 1.7068 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7141 13.9949 -0.1853 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5079 11.7096 -0.3731 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0411 13.9505 0.3267 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5166 1.4093 -2.1585 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8798 16.5933 0.0299 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6353 16.1160 -0.1558 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5021 15.5173 2.9922 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7466 15.9947 3.1779 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6062 20.0906 4.2473 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0876 0.0000 0.2831 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 26 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 27 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 28 1 0 0 0 0 9 10 1 0 0 0 0 9 29 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 30 1 0 0 0 0 13 31 1 0 0 0 0 13 32 1 0 0 0 0 13 33 1 0 0 0 0 14 15 2 0 0 0 0 14 34 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 23 1 0 0 0 0 17 35 1 0 0 0 0 18 19 1 0 0 0 0 18 36 1 0 0 0 0 18 37 1 0 0 0 0 19 20 1 0 0 0 0 19 38 1 0 0 0 0 19 39 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 40 1 0 0 0 0 23 25 1 0 0 0 0 23 24 2 0 0 0 0 25 41 1 0 0 0 0 M END > (240) 238 > (240) C18H16N2O5 > (240) 340.3348 > (240) FGFR-P238 > (240) 3-substituted indolin-2-one 11b > (240) FGFR-1 Tyrosine Kinase > (240) 770 > (240) BINDDB > (240) <2007 > (240) P > (240) TRAIN $$$$ 3-substituted indolin-2-one 11c csChFnd70/04170815452D 43 45 0 0 0 0 0 0 0 0999 V2000 3.0953 4.1490 0.0412 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8583 2.6224 -0.5313 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8410 4.2256 -0.4794 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4438 4.9877 -0.1902 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7953 6.6585 -0.2054 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4576 6.7563 -0.5184 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0041 5.3129 -0.6669 N 0 0 3 0 0 0 0 0 0 0 0 0 7.2096 7.9392 -0.6253 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7791 7.8654 0.0247 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3393 9.3878 0.1514 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5988 10.7142 -0.3505 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7207 9.8315 0.8030 N 0 0 3 0 0 0 0 0 0 0 0 0 2.0477 10.7993 -1.1319 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8416 11.3893 0.7049 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5614 11.9559 0.0053 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1357 2.5575 -0.0149 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5137 1.8006 -0.2998 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2336 13.6312 -0.3255 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2586 14.3093 0.9808 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9309 15.9847 0.6498 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4263 16.5757 -0.5116 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0886 16.8203 1.6454 O 0 0 0 0 0 0 0 0 0 0 0 0 1.8996 0.0000 0.7825 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4222 2.4511 1.1384 O 0 0 0 0 0 0 0 0 0 0 0 0 1.4315 1.4879 0.2772 S 0 0 0 0 0 0 0 0 0 0 0 0 0.6162 1.2448 -1.4338 N 0 0 0 0 0 0 0 0 0 0 0 0 2.0220 4.7400 0.2687 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9259 2.0188 -0.7530 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0742 5.0620 -0.8782 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5557 7.6427 0.1075 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4794 9.1448 1.2563 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1470 10.9253 -0.2632 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0230 11.7888 -1.9079 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8514 9.7456 -1.7899 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8005 12.0685 1.1195 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5366 0.5553 -0.3415 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3184 14.2619 -0.4098 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6063 13.7292 -1.4112 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1737 13.6785 1.0650 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8860 14.2112 2.0664 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9089 17.8899 1.3836 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.3324 -1.6355 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7546 2.0147 -2.2342 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 27 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 28 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 29 1 0 0 0 0 9 10 1 0 0 0 0 9 30 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 31 1 0 0 0 0 13 32 1 0 0 0 0 13 33 1 0 0 0 0 13 34 1 0 0 0 0 14 15 2 0 0 0 0 14 35 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 25 1 0 0 0 0 17 36 1 0 0 0 0 18 19 1 0 0 0 0 18 37 1 0 0 0 0 18 38 1 0 0 0 0 19 20 1 0 0 0 0 19 39 1 0 0 0 0 19 40 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 41 1 0 0 0 0 23 25 2 0 0 0 0 24 25 2 0 0 0 0 25 26 1 0 0 0 0 26 42 1 0 0 0 0 26 43 1 0 0 0 0 M END > (241) 239 > (241) C17H17N3O5S > (241) 375.3984 > (241) FGFR-P239 > (241) 3-substituted indolin-2-one 11c > (241) FGFR-1 Tyrosine Kinase > (241) 460 > (241) BINDDB > (241) <2007 > (241) P > (241) TRAIN $$$$ 3-substituted indolin-2-one 11d csChFnd70/04170815452D 42 44 0 0 0 0 0 0 0 0999 V2000 1.9455 6.5202 -0.3147 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3274 5.0846 -2.6127 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4057 6.8453 -2.2424 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2019 7.5601 -1.0836 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6161 9.4291 -0.9595 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1083 9.6832 -2.1139 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5103 8.1440 -2.8227 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8510 11.0504 -2.3825 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7802 10.6664 0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4695 12.3553 0.1528 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5298 13.8788 0.3054 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2015 12.7927 0.1536 N 0 0 3 0 0 0 0 0 0 0 0 0 0.5844 14.0417 0.3676 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3384 14.5406 0.2958 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7263 15.2341 0.3904 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8832 4.7740 -0.6946 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0725 4.0579 -1.8417 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3008 17.1328 0.5612 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0434 17.5829 2.4753 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6180 19.4815 2.6460 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5296 20.3821 1.3680 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3369 20.1720 4.2180 O 0 0 0 0 0 0 0 0 0 0 0 0 3.0036 2.3368 -2.2107 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6787 1.3497 -1.3736 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0254 7.0771 0.5812 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2459 4.5158 -3.5028 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4519 7.9624 -3.6356 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5984 10.3411 0.7042 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1620 11.9862 0.0673 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1484 13.9680 1.7092 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1979 15.2828 -0.1856 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.9923 -0.3758 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5374 15.2621 0.3310 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9097 3.9631 -0.0994 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3623 17.9024 0.0351 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1149 17.4157 -0.1527 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9819 16.8132 3.0014 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2292 17.3000 3.1892 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0684 21.3954 4.2623 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4121 1.8650 -1.7287 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7689 0.0000 -1.7807 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8446 1.4314 0.0270 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 25 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 26 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 27 1 0 0 0 0 9 10 1 0 0 0 0 9 28 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 29 1 0 0 0 0 13 30 1 0 0 0 0 13 31 1 0 0 0 0 13 32 1 0 0 0 0 14 15 2 0 0 0 0 14 33 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 34 1 0 0 0 0 17 23 1 0 0 0 0 18 19 1 0 0 0 0 18 35 1 0 0 0 0 18 36 1 0 0 0 0 19 20 1 0 0 0 0 19 37 1 0 0 0 0 19 38 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 24 40 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 M END > (242) 240 > (242) C18H18N2O4 > (242) 326.3512 > (242) FGFR-P240 > (242) 3-substituted indolin-2-one 11d > (242) FGFR-1 Tyrosine Kinase > (242) 3890 > (242) BINDDB > (242) <2007 > (242) P > (242) TRAIN $$$$ 3-substituted indolin-2-one 11e csChFnd70/04170815452D 48 51 0 0 0 0 0 0 0 0999 V2000 1.9159 8.1980 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5997 6.7402 -0.5141 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5702 8.2843 -0.4628 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2162 9.0120 -0.1834 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5459 10.6255 -0.1981 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1498 10.7302 -0.5002 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6864 9.3410 -0.6437 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8679 11.8763 -0.6031 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5577 11.7847 0.0237 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0893 13.2568 0.1460 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3672 14.5326 -0.3385 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4196 13.6931 0.7753 N 0 0 3 0 0 0 0 0 0 0 0 0 0.8702 14.6057 -1.0931 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5274 15.1971 0.6801 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2888 15.7363 0.0046 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9549 6.6656 -0.0118 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2967 5.9318 -0.2890 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9630 17.3510 -0.3150 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0183 18.0000 0.9455 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6924 19.6148 0.6258 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1671 20.1877 -0.4951 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8749 20.4165 1.5864 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3341 4.2818 -0.3444 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6713 3.5416 -0.6143 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6995 2.0061 -0.6648 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4040 1.2016 -0.4480 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0738 1.9302 -0.1796 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0336 3.4652 -0.1204 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8793 8.7669 0.2599 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6342 6.1655 -0.7284 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7206 9.1056 -0.8475 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3786 11.5626 0.1032 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1557 13.0349 1.2130 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.7220 -0.2550 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8408 15.5603 -1.8419 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6869 13.5876 -1.7280 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4488 15.8581 1.0803 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9477 6.0320 0.1620 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0061 17.9658 -0.3965 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3570 17.4418 -1.3627 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9751 17.3851 1.0269 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6242 17.9092 1.9932 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6954 21.4475 1.3336 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6834 4.1686 -0.7841 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7349 1.4314 -0.8742 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4311 0.0000 -0.4888 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0657 1.2966 -0.0112 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9952 4.0328 0.0941 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 29 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 30 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 31 1 0 0 0 0 9 10 1 0 0 0 0 9 32 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 33 1 0 0 0 0 13 34 1 0 0 0 0 13 35 1 0 0 0 0 13 36 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 38 1 0 0 0 0 17 23 1 0 0 0 0 18 19 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 19 20 1 0 0 0 0 19 41 1 0 0 0 0 19 42 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 43 1 0 0 0 0 23 28 2 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 26 27 2 0 0 0 0 26 46 1 0 0 0 0 27 28 1 0 0 0 0 27 47 1 0 0 0 0 28 48 1 0 0 0 0 M END > (243) 241 > (243) C23H20N2O3 > (243) 372.4226 > (243) FGFR-P241 > (243) 3-substituted indolin-2-one 11e > (243) FGFR-1 Tyrosine Kinase > (243) 1050 > (243) BINDDB > (243) <2007 > (243) P > (243) TRAIN $$$$ 3-substituted indolin-2-one 11f csChFnd70/04170815452D 52 55 0 0 0 0 0 0 0 0999 V2000 2.0735 9.1544 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7566 7.6968 -0.5138 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7272 9.2404 -0.4630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3736 9.9681 -0.1836 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7032 11.5814 -0.1991 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3065 11.6859 -0.5018 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8430 10.2969 -0.6448 N 0 0 3 0 0 0 0 0 0 0 0 0 6.0244 12.8317 -0.6058 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7154 12.7403 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2469 14.2122 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5247 15.4874 -0.3404 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5771 14.6486 0.7723 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0279 15.5600 -1.0947 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6843 16.1521 0.6773 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4458 16.6911 0.0024 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1124 7.6223 -0.0118 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4538 6.8887 -0.2891 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1198 18.3052 -0.3174 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1751 18.9541 0.9426 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8491 20.5684 0.6228 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3235 21.1412 -0.4979 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0315 21.3699 1.5829 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4909 5.2391 -0.3452 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1895 4.4239 -0.1280 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2315 2.8838 -0.1822 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5679 2.1560 -0.4523 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8597 2.9639 -0.6673 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8270 4.4998 -0.6216 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9643 2.0848 0.0296 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0894 0.5005 -0.0414 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0371 9.7233 0.2599 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7907 7.1222 -0.7284 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8770 10.0615 -0.8482 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5365 12.5183 0.1032 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3135 13.9908 1.2097 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1580 15.6763 -0.2569 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9983 16.5144 -1.8436 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8449 14.5422 -1.7294 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6057 16.8134 1.0768 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1053 6.9889 0.1621 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1626 18.9202 -0.3989 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5140 18.3957 -1.3648 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1322 18.3393 1.0241 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7809 18.8637 1.9901 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8518 22.4007 1.3300 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1507 4.9917 0.0824 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5983 0.9548 -0.4941 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8964 2.3923 -0.8766 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8373 5.1282 -0.7949 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5005 0.1758 -1.1359 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8629 0.1171 0.8113 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.0000 0.1463 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 31 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 32 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 33 1 0 0 0 0 9 10 1 0 0 0 0 9 34 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 35 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 14 15 2 0 0 0 0 14 39 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 23 1 0 0 0 0 18 19 1 0 0 0 0 18 41 1 0 0 0 0 18 42 1 0 0 0 0 19 20 1 0 0 0 0 19 43 1 0 0 0 0 19 44 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 45 1 0 0 0 0 23 28 2 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 46 1 0 0 0 0 25 26 1 0 0 0 0 25 29 1 0 0 0 0 26 27 2 0 0 0 0 26 47 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 28 49 1 0 0 0 0 29 30 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 M END > (244) 242 > (244) C24H22N2O4 > (244) 402.4488 > (244) FGFR-P242 > (244) 3-substituted indolin-2-one 11f > (244) FGFR-1 Tyrosine Kinase > (244) 360 > (244) BINDDB > (244) <2007 > (244) P > (244) TRAIN $$$$ 3-substituted indolin-2-one 11g csChFnd70/04170815452D 52 55 0 0 0 0 0 0 0 0999 V2000 2.2358 9.5689 0.0473 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3677 7.8682 -0.5999 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3330 9.6696 -0.5399 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7531 10.5186 -0.2140 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1375 12.4014 -0.2322 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0088 12.5235 -0.5851 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6350 10.9027 -0.7519 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8465 13.8608 -0.7061 O 0 0 0 0 0 0 0 0 0 0 0 0 2.9848 13.7537 0.0266 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6049 15.4716 0.1682 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7619 16.9594 -0.3973 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1572 15.9810 0.9014 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0142 17.0442 -1.2759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2827 17.7359 0.7895 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8372 18.3644 0.0018 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2813 7.7810 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8472 6.9247 -0.3371 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4568 20.2480 -0.3722 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3548 21.0062 1.0982 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9744 22.8899 0.7241 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5279 23.5575 -0.5844 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0209 23.8261 1.8444 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8908 5.0003 -0.4018 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1981 2.2273 0.8702 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9731 1.4018 -0.5241 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7121 2.3630 -1.8509 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6750 4.1551 -1.7969 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1513 4.0248 0.9414 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3907 4.8374 2.3111 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6629 3.7570 3.6337 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0266 10.2328 0.3031 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5745 7.1978 -0.8504 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8419 10.6281 -0.9892 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6090 13.4945 0.1203 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0161 15.2134 1.4126 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.1809 -0.2971 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9792 18.1575 -2.1505 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7996 15.8559 -2.0156 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3577 18.5076 1.2561 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1061 7.0418 0.1892 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6740 20.9655 -0.4680 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7495 20.3532 -1.5944 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1377 20.2889 1.1939 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0621 20.9011 2.3204 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8112 25.0289 1.5487 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6281 1.4697 1.9046 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0068 0.0000 -0.5747 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3152 1.7088 -2.9357 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2529 4.9012 -2.8351 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6557 2.9357 3.0713 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6791 2.9432 4.1907 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0987 4.5681 4.6482 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 31 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 32 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 33 1 0 0 0 0 9 10 1 0 0 0 0 9 34 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 35 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 14 15 2 0 0 0 0 14 39 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 23 1 0 0 0 0 18 19 1 0 0 0 0 18 41 1 0 0 0 0 18 42 1 0 0 0 0 19 20 1 0 0 0 0 19 43 1 0 0 0 0 19 44 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 45 1 0 0 0 0 23 27 2 0 0 0 0 23 28 1 0 0 0 0 24 28 2 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 25 26 2 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 29 30 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 M END > (245) 243 > (245) C24H22N2O4 > (245) 402.4488 > (245) FGFR-P243 > (245) 3-substituted indolin-2-one 11g > (245) FGFR-1 Tyrosine Kinase > (245) 2130 > (245) BINDDB > (245) <2007 > (245) P > (245) TRAIN $$$$ 3-substituted indolin-2-one 11h csChFnd70/04170815452D 52 55 0 0 0 0 0 0 0 0999 V2000 1.9157 10.4672 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5992 9.0100 -0.5145 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5694 10.5537 -0.4635 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2157 11.2811 -0.1838 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5452 12.8945 -0.1988 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1486 12.9992 -0.5015 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6851 11.6103 -0.6450 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8665 14.1450 -0.6048 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5575 14.0531 0.0239 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0890 15.5250 0.1457 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3666 16.8002 -0.3382 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4193 15.9612 0.7739 N 0 0 3 0 0 0 0 0 0 0 0 0 0.8692 16.8733 -1.0911 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5268 17.4649 0.6785 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2882 18.0038 0.0041 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9548 8.9352 -0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2964 8.2016 -0.2895 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9620 19.6182 -0.3154 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0185 20.2671 0.9454 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6923 21.8815 0.6260 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1660 22.4542 -0.4950 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8755 22.6830 1.5868 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3338 6.5523 -0.3457 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7002 4.2799 -0.6808 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4035 3.4710 -0.4511 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0707 4.2031 -0.1751 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0323 5.7368 -0.1217 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6692 5.8138 -0.6288 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4377 1.9597 -0.5029 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0633 1.1974 -0.2566 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8795 11.0360 0.2600 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6334 8.4356 -0.7288 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7191 11.3752 -0.8495 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3787 13.8310 0.1046 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1556 15.3033 1.2111 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9897 -0.2524 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8390 17.8275 -1.8399 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6853 15.8554 -1.7254 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4484 18.1260 1.0779 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9479 8.3017 0.1621 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0050 20.2330 -0.3975 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3555 19.7089 -1.3623 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9755 19.6524 1.0276 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6249 20.1765 1.9924 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6958 23.7138 1.3341 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7343 3.7073 -0.9001 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0638 3.5707 0.0029 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9953 6.3057 0.0937 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6783 6.4425 -0.8077 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2573 1.5343 -1.0985 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2466 0.0000 -0.3283 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6381 1.4762 0.8451 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 4 2 0 0 0 0 1 31 1 0 0 0 0 2 17 1 0 0 0 0 2 3 2 0 0 0 0 2 32 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 33 1 0 0 0 0 9 10 1 0 0 0 0 9 34 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 15 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 35 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 14 15 2 0 0 0 0 14 39 1 0 0 0 0 15 18 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 23 1 0 0 0 0 18 19 1 0 0 0 0 18 41 1 0 0 0 0 18 42 1 0 0 0 0 19 20 1 0 0 0 0 19 43 1 0 0 0 0 19 44 1 0 0 0 0 20 22 1 0 0 0 0 20 21 2 0 0 0 0 22 45 1 0 0 0 0 23 27 2 0 0 0 0 23 28 1 0 0 0 0 24 28 2 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 25 26 2 0 0 0 0 25 29 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 28 49 1 0 0 0 0 29 30 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 M END > (246) 244 > (246) C24H22N2O4 > (246) 402.4488 > (246) FGFR-P244 > (246) 3-substituted indolin-2-one 11h > (246) FGFR-1 Tyrosine Kinase > (246) 1540 > (246) BINDDB > (246) <2007 > (246) P > (246) TRAIN $$$$ 3-substituted indolin-2-one 16b csChFnd70/04170815452D 41 43 0 0 0 0 0 0 0 0999 V2000 1.9315 3.8297 -0.3160 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3065 2.3876 -2.6125 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3913 4.1491 -2.2426 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1897 4.8677 -1.0840 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6087 6.7354 -0.9606 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1014 6.9857 -2.1151 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4996 5.4449 -2.8236 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8474 8.3513 -2.3839 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7755 7.9756 0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4690 9.6623 0.1517 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5329 11.1888 0.3041 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2024 10.0957 0.1521 N 0 0 3 0 0 0 0 0 0 0 0 0 0.5877 11.3567 0.3675 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3436 11.8431 0.2939 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8680 2.0819 -0.6990 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0536 1.3675 -1.8434 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0194 12.8459 0.3416 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7326 12.5408 0.3886 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3121 14.4409 0.5592 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2154 14.9269 2.4796 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7950 16.8267 2.6501 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5931 17.7023 1.3672 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6445 17.5463 4.2270 O 0 0 0 0 0 0 0 0 0 0 0 0 0.1616 0.6622 0.3408 Br 0 0 0 0 0 0 0 0 0 0 0 0 1.0119 4.3870 0.5804 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2227 1.8158 -3.5031 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4405 5.2610 -3.6371 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5931 7.6532 0.7038 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1610 9.2867 0.0659 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1523 11.2850 1.7097 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2039 12.5987 -0.1863 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.3082 -0.3751 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9966 0.0000 -2.1370 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3955 13.1972 -0.9743 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8448 14.0184 1.1103 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0297 12.0475 0.9230 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3206 15.2048 -0.0697 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0683 14.7051 -0.0566 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2070 14.1628 3.1085 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4593 14.6627 3.0952 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3733 18.7694 4.2710 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 25 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 26 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 27 1 0 0 0 0 9 10 1 0 0 0 0 9 28 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 29 1 0 0 0 0 13 30 1 0 0 0 0 13 31 1 0 0 0 0 13 32 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 24 1 0 0 0 0 16 33 1 0 0 0 0 17 34 1 0 0 0 0 17 35 1 0 0 0 0 17 36 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 37 1 0 0 0 0 19 38 1 0 0 0 0 20 21 1 0 0 0 0 20 39 1 0 0 0 0 20 40 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 41 1 0 0 0 0 M END > (247) 245 > (247) C18H17BrN2O3 > (247) 389.2479 > (247) FGFR-P245 > (247) 3-substituted indolin-2-one 16b > (247) FGFR-1 Tyrosine Kinase > (247) 2050 > (247) BINDDB > (247) <2007 > (247) P > (247) TRAIN $$$$ 3-substituted indolin-2-one 16c csChFnd70/04170815452D 44 46 0 0 0 0 0 0 0 0999 V2000 2.4317 5.2467 -0.3177 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8096 3.7979 -2.6149 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8883 5.5590 -2.2396 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6859 6.2762 -1.0819 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1054 8.1405 -0.9575 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5957 8.3867 -2.1089 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9909 6.8486 -2.8148 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3429 9.7477 -2.3776 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2750 9.3794 0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9690 11.0617 0.1515 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0368 12.5861 0.3034 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6994 11.4921 0.1517 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0960 12.7559 0.3673 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8424 13.2356 0.2922 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3673 3.4841 -0.7049 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5671 2.7730 -1.8591 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5158 14.2343 0.3404 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2358 13.9339 0.3867 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8183 15.8304 0.5560 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7231 16.3165 2.4721 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3057 18.2131 2.6415 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1050 19.0862 1.3609 O 0 0 0 0 0 0 0 0 0 0 0 0 3.1569 18.9321 4.2147 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0400 2.3753 0.0999 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.9953 1.1018 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9805 0.6743 -0.2760 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5140 5.8039 0.5760 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7285 3.2350 -3.5039 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9303 6.6645 -3.6259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0942 9.0595 0.7017 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6550 10.6836 0.0664 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6618 12.6851 1.7069 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7142 13.9956 -0.1853 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5080 11.7102 -0.3731 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5167 1.4095 -2.1588 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8927 14.5834 -0.9726 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3425 15.4050 1.1066 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5223 13.4366 0.9220 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8253 16.5913 -0.0723 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5772 16.0952 -0.0582 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7161 15.5557 3.1005 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9642 16.0517 3.0863 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8878 20.1529 4.2579 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0877 0.0000 0.2831 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 27 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 28 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 29 1 0 0 0 0 9 10 1 0 0 0 0 9 30 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 31 1 0 0 0 0 13 32 1 0 0 0 0 13 33 1 0 0 0 0 13 34 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 24 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 39 1 0 0 0 0 19 40 1 0 0 0 0 20 21 1 0 0 0 0 20 41 1 0 0 0 0 20 42 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 43 1 0 0 0 0 24 26 1 0 0 0 0 24 25 2 0 0 0 0 26 44 1 0 0 0 0 M END > (248) 246 > (248) C19H18N2O5 > (248) 354.3616 > (248) FGFR-P246 > (248) 3-substituted indolin-2-one 16c > (248) FGFR-1 Tyrosine Kinase > (248) 280 > (248) BINDDB > (248) <2007 > (248) P > (248) TRAIN $$$$ 3-substituted indolin-2-one 16d csChFnd70/04170815452D 46 48 0 0 0 0 0 0 0 0999 V2000 4.1287 4.7883 -0.3162 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5035 3.3459 -2.6112 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5884 5.1076 -2.2422 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3868 5.8261 -1.0839 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8059 7.6936 -0.9602 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2985 7.9436 -2.1146 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6965 6.4030 -2.8227 N 0 0 3 0 0 0 0 0 0 0 0 0 8.0449 9.3088 -2.3834 O 0 0 0 0 0 0 0 0 0 0 0 0 4.9728 8.9340 0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6665 10.6203 0.1516 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7306 12.1467 0.3039 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3997 11.0535 0.1520 N 0 0 3 0 0 0 0 0 0 0 0 0 2.7857 12.3149 0.3670 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5411 12.8006 0.2938 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0652 3.0415 -0.6990 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2502 2.3270 -1.8420 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2168 13.8030 0.3425 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9305 13.4985 0.3886 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5102 15.3984 0.5587 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4132 15.8845 2.4788 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9929 17.7844 2.6488 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7916 18.6597 1.3661 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8423 18.5041 4.2255 O 0 0 0 0 0 0 0 0 0 0 0 0 3.1339 0.0000 0.2310 O 0 0 0 0 0 0 0 0 0 0 0 0 1.9664 2.5691 1.8219 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4746 1.7193 0.2689 S 0 0 0 0 0 0 0 0 0 0 0 0 0.7600 1.7396 -1.0219 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2089 5.3453 0.5798 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4198 2.7737 -3.5013 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6379 6.2185 -3.6356 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7904 8.6118 0.7035 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3583 10.2444 0.0661 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3501 12.2428 1.7090 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4023 13.5568 -0.1866 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1980 11.2667 -0.3757 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1929 0.9595 -2.1349 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5940 14.1541 -0.9728 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0419 14.9754 1.1111 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2263 13.0046 0.9247 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5188 16.1620 -0.0701 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2666 15.6626 -0.0573 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4046 15.1210 3.1075 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6569 15.6203 3.0948 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5714 19.7271 4.2692 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.7394 -1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5158 2.7514 -1.7268 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 28 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 30 1 0 0 0 0 9 10 1 0 0 0 0 9 31 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 32 1 0 0 0 0 13 33 1 0 0 0 0 13 34 1 0 0 0 0 13 35 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 26 1 0 0 0 0 16 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 17 39 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 19 41 1 0 0 0 0 20 21 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 44 1 0 0 0 0 24 26 2 0 0 0 0 25 26 2 0 0 0 0 26 27 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 M END > (249) 247 > (249) C18H19N3O5S > (249) 389.4252 > (249) FGFR-P247 > (249) 3-substituted indolin-2-one 16d > (249) FGFR-1 Tyrosine Kinase > (249) 280 > (249) BINDDB > (249) <2007 > (249) P > (249) TRAIN $$$$ 3-substituted indolin-2-one 16e csChFnd70/04170815452D 45 47 0 0 0 0 0 0 0 0999 V2000 1.9625 6.5761 -0.3174 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3639 5.1280 -2.6355 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4435 6.9036 -2.2617 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2296 7.6246 -1.0930 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6474 9.5097 -0.9682 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1521 9.7657 -2.1328 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5574 8.2132 -2.8472 N 0 0 3 0 0 0 0 0 0 0 0 0 5.9015 11.1445 -2.4035 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8043 10.7577 0.0275 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4997 12.4609 0.1531 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5520 13.9974 0.3068 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2465 12.9022 0.1536 N 0 0 3 0 0 0 0 0 0 0 0 0 0.5902 14.1618 0.3714 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3846 14.6650 0.2955 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8993 4.8151 -0.7004 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0985 4.0926 -1.8574 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0718 15.6804 0.3443 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7586 15.3645 0.3910 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3295 17.2794 0.5626 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2319 17.7697 2.4991 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8027 19.6845 2.6707 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5963 20.5665 1.3770 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6499 20.4102 4.2609 O 0 0 0 0 0 0 0 0 0 0 0 0 3.0291 2.3567 -2.2290 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6933 1.3615 -1.3843 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0347 7.1380 0.5863 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2896 4.5544 -3.5339 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5075 8.0298 -3.6666 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6129 10.4298 0.7098 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2152 12.0886 0.0668 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1518 14.0883 1.7249 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1996 15.4129 -0.1872 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 13.1027 -0.3771 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9176 3.9973 -0.1001 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4514 16.0347 -0.9825 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8923 16.8629 1.1187 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0922 14.8782 0.9320 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3441 18.0522 -0.0724 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0741 17.5422 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2172 16.9968 3.1341 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4873 17.5068 3.1194 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3733 21.6428 4.3049 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4158 1.8810 -1.7422 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7843 0.0000 -1.7945 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8609 1.4442 0.0282 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 26 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 27 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 28 1 0 0 0 0 9 10 1 0 0 0 0 9 29 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 30 1 0 0 0 0 13 31 1 0 0 0 0 13 32 1 0 0 0 0 13 33 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 24 1 0 0 0 0 17 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 38 1 0 0 0 0 19 39 1 0 0 0 0 20 21 1 0 0 0 0 20 40 1 0 0 0 0 20 41 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 M END > (250) 248 > (250) C19H20N2O4 > (250) 340.378 > (250) FGFR-P248 > (250) 3-substituted indolin-2-one 16e > (250) FGFR-1 Tyrosine Kinase > (250) 5400 > (250) BINDDB > (250) <2007 > (250) P > (250) TRAIN $$$$ 3-substituted indolin-2-one 16f csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 1.9153 8.1956 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5984 6.7381 -0.5141 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5689 8.2816 -0.4632 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2154 9.0093 -0.1837 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5449 10.6225 -0.1991 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1482 10.7269 -0.5019 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6847 9.3381 -0.6451 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8661 11.8727 -0.6060 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5572 11.7812 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0887 13.2531 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3664 14.5282 -0.3404 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4190 13.6894 0.7723 N 0 0 3 0 0 0 0 0 0 0 0 0 0.8695 14.6010 -1.0940 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5262 15.1930 0.6773 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9543 6.6636 -0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2957 5.9300 -0.2893 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8117 16.1154 1.2347 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2876 15.7318 0.0024 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9614 17.3460 -0.3172 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1366 18.0314 1.0059 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8104 19.6454 0.6862 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1980 20.1916 -0.4802 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0895 20.4764 1.6971 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3329 4.2805 -0.3453 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6696 3.5405 -0.6155 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6976 2.0053 -0.6658 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4024 1.2012 -0.4488 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0725 1.9297 -0.1809 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0323 3.4642 -0.1217 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8793 8.7644 0.2599 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6326 6.1636 -0.7282 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7186 9.1028 -0.8485 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3786 11.5593 0.1032 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1552 13.0317 1.2094 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.7176 -0.2558 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8398 15.5550 -1.8430 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6861 13.5830 -1.7281 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9474 6.0303 0.1621 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6352 16.2365 0.3520 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4096 17.2113 1.5658 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3200 15.5657 2.1894 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0034 17.9413 -0.4966 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2713 17.4299 -1.3116 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0947 17.4361 1.1852 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8267 17.9474 2.0003 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9056 21.5059 1.4421 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6813 4.1672 -0.7853 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7326 1.4308 -0.8754 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4296 0.0000 -0.4892 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0649 1.2963 -0.0127 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9945 4.0317 0.0925 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 30 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 31 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 32 1 0 0 0 0 9 10 1 0 0 0 0 9 33 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 34 1 0 0 0 0 13 35 1 0 0 0 0 13 36 1 0 0 0 0 13 37 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 38 1 0 0 0 0 16 24 1 0 0 0 0 17 39 1 0 0 0 0 17 40 1 0 0 0 0 17 41 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 42 1 0 0 0 0 19 43 1 0 0 0 0 20 21 1 0 0 0 0 20 44 1 0 0 0 0 20 45 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 46 1 0 0 0 0 24 29 2 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 27 28 2 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > (251) 249 > (251) C24H22N2O3 > (251) 386.4494 > (251) FGFR-P249 > (251) 3-substituted indolin-2-one 16f > (251) FGFR-1 Tyrosine Kinase > (251) 2290 > (251) BINDDB > (251) <2007 > (251) P > (251) TRAIN $$$$ 3-substituted indolin-2-one 16g csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 2.0731 9.1545 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7562 7.6968 -0.5142 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7268 9.2405 -0.4627 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3732 9.9682 -0.1835 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7029 11.5814 -0.1990 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3063 11.6860 -0.5016 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8427 10.2970 -0.6445 N 0 0 3 0 0 0 0 0 0 0 0 0 6.0242 12.8318 -0.6052 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7150 12.7404 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2466 14.2123 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5243 15.4875 -0.3405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5769 14.6487 0.7723 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0272 15.5603 -1.0940 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6846 16.1522 0.6765 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1120 7.6224 -0.0118 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4535 6.8888 -0.2890 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9703 17.0747 1.2335 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4459 16.6911 0.0016 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1200 18.3052 -0.3185 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2959 18.9914 1.0048 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9700 20.6055 0.6847 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3570 21.1514 -0.4821 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2495 21.4371 1.6959 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4907 5.2391 -0.3444 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1893 4.4240 -0.1269 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2315 2.8838 -0.1806 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5679 2.1559 -0.4501 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8596 2.9638 -0.6655 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8267 4.4998 -0.6207 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9642 2.0848 0.0312 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0892 0.5004 -0.0393 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0368 9.7234 0.2598 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7903 7.1223 -0.7289 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8767 10.0616 -0.8481 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5363 12.5185 0.1031 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3128 13.9909 1.2101 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1577 15.6768 -0.2558 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9975 16.5145 -1.8432 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8437 14.5423 -1.7283 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1049 6.9892 0.1620 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7942 17.1951 0.3509 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5684 18.1709 1.5640 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4783 16.5254 2.1888 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1620 18.9004 -0.4986 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4294 18.3890 -1.3127 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2539 18.3963 1.1849 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9865 18.9077 1.9989 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0656 22.4666 1.4405 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1505 4.9916 0.0835 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5986 0.9547 -0.4911 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8964 2.3923 -0.8743 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8369 5.1280 -0.7945 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.0000 0.1483 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5009 0.1753 -1.1335 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8627 0.1174 0.8137 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 32 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 33 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 34 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 40 1 0 0 0 0 16 24 1 0 0 0 0 17 41 1 0 0 0 0 17 42 1 0 0 0 0 17 43 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 44 1 0 0 0 0 19 45 1 0 0 0 0 20 21 1 0 0 0 0 20 46 1 0 0 0 0 20 47 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 48 1 0 0 0 0 24 29 2 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 49 1 0 0 0 0 26 27 1 0 0 0 0 26 30 1 0 0 0 0 27 28 2 0 0 0 0 27 50 1 0 0 0 0 28 29 1 0 0 0 0 28 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > (252) 250 > (252) C25H24N2O4 > (252) 416.4756 > (252) FGFR-P250 > (252) 3-substituted indolin-2-one 16g > (252) FGFR-1 Tyrosine Kinase > (252) 1400 > (252) BINDDB > (252) <2007 > (252) P > (252) TRAIN $$$$ 3-substituted indolin-2-one 16h csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 2.2361 9.5688 0.0473 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3677 7.8681 -0.6005 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3330 9.6695 -0.5404 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7534 10.5185 -0.2142 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1378 12.4013 -0.2324 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0089 12.5236 -0.5857 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6350 10.9026 -0.7526 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8467 13.8608 -0.7063 O 0 0 0 0 0 0 0 0 0 0 0 0 2.9849 13.7536 0.0262 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6050 15.4715 0.1680 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7620 16.9593 -0.3978 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1571 15.9809 0.9015 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0153 17.0440 -1.2781 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2821 17.7358 0.7904 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2816 7.7809 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8474 6.9246 -0.3375 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7824 18.8125 1.4408 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8368 18.3643 0.0025 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4565 20.2481 -0.3717 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4927 21.0486 1.1714 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1123 22.9323 0.7973 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5655 23.5692 -0.5640 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2699 23.9026 1.9761 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8911 5.0003 -0.4022 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1386 4.0248 0.9337 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1850 2.2271 0.8621 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9724 1.4018 -0.5251 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7176 2.3630 -1.8483 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6749 4.1551 -1.7974 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3658 4.8371 2.2965 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6251 3.7568 3.6122 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0268 10.2327 0.3034 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5745 7.1977 -0.8512 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8418 10.6281 -0.9905 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6091 13.4944 0.1198 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0163 15.2133 1.4120 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.1798 -0.3002 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9807 18.1575 -2.1523 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8017 15.8559 -2.0185 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1064 7.0417 0.1893 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7435 18.9539 0.4104 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3130 20.0915 1.8271 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3758 18.1710 2.5550 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6726 20.9427 -0.5805 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6518 20.3455 -1.5329 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2764 20.3540 1.3802 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2972 20.9512 2.3326 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0554 25.1038 1.6779 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6058 1.4696 1.8914 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0062 0.0000 -0.5759 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3307 1.7089 -2.9276 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2534 4.9012 -2.8354 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6357 2.9421 4.1780 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0521 4.5677 4.6215 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6227 2.9362 3.0400 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 32 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 33 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 34 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 40 1 0 0 0 0 16 24 1 0 0 0 0 17 41 1 0 0 0 0 17 42 1 0 0 0 0 17 43 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 44 1 0 0 0 0 19 45 1 0 0 0 0 20 21 1 0 0 0 0 20 46 1 0 0 0 0 20 47 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 48 1 0 0 0 0 24 29 2 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 30 1 0 0 0 0 26 27 1 0 0 0 0 26 49 1 0 0 0 0 27 28 2 0 0 0 0 27 50 1 0 0 0 0 28 29 1 0 0 0 0 28 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > (253) 251 > (253) C25H24N2O4 > (253) 416.4756 > (253) FGFR-P251 > (253) 3-substituted indolin-2-one 16h > (253) FGFR-1 Tyrosine Kinase > (253) 7330 > (253) BINDDB > (253) <2007 > (253) P > (253) TRAIN $$$$ 3-substituted indolin-2-one 16i csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 1.9157 10.4681 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5995 9.0104 -0.5132 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5699 10.5543 -0.4625 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2161 11.2820 -0.1833 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5456 12.8955 -0.1988 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1493 13.0001 -0.5012 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6858 11.6110 -0.6442 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8673 14.1459 -0.6049 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5577 14.0544 0.0225 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0892 15.5266 0.1440 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3668 16.8018 -0.3410 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4194 15.9631 0.7725 N 0 0 3 0 0 0 0 0 0 0 0 0 0.8696 16.8745 -1.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5270 17.4670 0.6766 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9547 8.9360 -0.0117 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2965 8.2022 -0.2887 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8126 18.3896 1.2340 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2885 18.0056 0.0012 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9626 19.6199 -0.3195 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1377 20.3064 1.0033 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8118 21.9208 0.6826 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1997 22.4663 -0.4843 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0908 22.7528 1.6932 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3337 6.5526 -0.3447 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6718 5.8136 -0.6146 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7028 4.2795 -0.6653 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4034 3.4709 -0.4486 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0690 4.2036 -0.1801 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0319 5.7372 -0.1210 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4375 1.9595 -0.4998 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0603 1.1976 -0.2672 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8794 11.0372 0.2597 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6339 8.4358 -0.7271 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7199 11.3756 -0.8480 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3786 13.8324 0.1024 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1554 15.3053 1.2105 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9913 -0.2563 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8399 17.8285 -1.8440 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6860 15.8561 -1.7287 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9476 8.3026 0.1620 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6368 18.5100 0.3515 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4106 19.4859 1.5642 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3205 17.8403 2.1896 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0049 20.2150 -0.4992 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2724 19.7035 -1.3142 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0954 19.7114 1.1830 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8279 20.2229 1.9980 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9071 23.7822 1.4374 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6828 6.4420 -0.7840 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7390 3.7064 -0.8744 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0600 3.5715 -0.0127 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9945 6.3064 0.0927 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2438 0.0000 -0.3368 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6238 1.4768 0.8301 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2630 1.5347 -1.1176 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 32 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 33 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 34 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 36 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 13 39 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 40 1 0 0 0 0 16 24 1 0 0 0 0 17 41 1 0 0 0 0 17 42 1 0 0 0 0 17 43 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 44 1 0 0 0 0 19 45 1 0 0 0 0 20 21 1 0 0 0 0 20 46 1 0 0 0 0 20 47 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 48 1 0 0 0 0 24 29 2 0 0 0 0 24 25 1 0 0 0 0 25 26 2 0 0 0 0 25 49 1 0 0 0 0 26 27 1 0 0 0 0 26 50 1 0 0 0 0 27 28 2 0 0 0 0 27 30 1 0 0 0 0 28 29 1 0 0 0 0 28 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > (254) 252 > (254) C25H24N2O4 > (254) 416.4756 > (254) FGFR-P252 > (254) 3-substituted indolin-2-one 16i > (254) FGFR-1 Tyrosine Kinase > (254) 5760 > (254) BINDDB > (254) <2007 > (254) P > (254) TRAIN $$$$ 3-substituted indolin-2-one 9a csChFnd70/04170815452D 41 43 0 0 0 0 0 0 0 0999 V2000 5.1714 3.9397 0.2438 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9145 2.1761 -0.1652 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9189 1.3804 -1.4775 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1835 2.3346 -2.3903 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4620 4.1121 -1.9974 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4425 4.9129 -0.6678 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0381 6.7772 -0.5632 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4335 6.9389 -1.9087 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6253 5.3546 -2.6969 N 0 0 3 0 0 0 0 0 0 0 0 0 9.2713 8.2751 -2.2496 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4158 8.0833 0.5578 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2691 9.7436 0.6216 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4539 11.3780 0.8122 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0676 10.0394 0.5139 N 0 0 3 0 0 0 0 0 0 0 0 0 4.4941 11.7132 0.9886 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9763 11.6776 2.9476 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0165 12.0128 3.1239 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1252 12.2552 1.8170 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2608 12.0420 4.7331 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3655 11.8080 0.6272 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7915 12.6547 0.8098 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5328 14.6263 0.9841 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0739 4.8089 1.6667 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9289 1.4158 0.5398 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7109 0.0000 -1.7897 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9585 1.6991 -3.4110 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4668 5.1104 -3.6367 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2761 7.8326 1.3851 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9696 9.1342 0.3800 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1746 13.0055 0.4297 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7649 10.6887 0.2795 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2958 10.3855 3.5065 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7055 12.7024 3.6567 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.2621 4.7795 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6484 12.4390 0.5832 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5740 14.9956 2.3793 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5840 15.3144 0.2730 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2532 14.9950 0.4264 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7995 4.7873 2.9147 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7981 6.1761 1.2938 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8303 4.0918 1.8206 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 23 1 0 0 0 0 2 3 2 0 0 0 0 2 24 1 0 0 0 0 3 4 1 0 0 0 0 3 25 1 0 0 0 0 4 5 2 0 0 0 0 4 26 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 27 1 0 0 0 0 11 12 1 0 0 0 0 11 28 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 29 1 0 0 0 0 15 16 1 0 0 0 0 15 30 1 0 0 0 0 15 31 1 0 0 0 0 16 17 1 0 0 0 0 16 32 1 0 0 0 0 16 33 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 34 1 0 0 0 0 20 21 2 0 0 0 0 20 35 1 0 0 0 0 21 22 1 0 0 0 0 22 36 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 M END > (255) 253 > (255) C18H18N2O3 > (255) 310.3518 > (255) FGFR-P253 > (255) 3-substituted indolin-2-one 9a > (255) FGFR-1 Tyrosine Kinase > (255) 30 > (255) BINDDB > (255) <2007 > (255) P > (255) TRAIN $$$$ 3-substituted indolin-2-one 9b csChFnd70/04170815452D 38 40 0 0 0 0 0 0 0 0999 V2000 5.5983 3.5894 -0.2960 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6492 1.2817 -1.7274 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8233 2.2372 -2.4484 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9027 3.8884 -2.1023 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7773 4.5618 -1.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1700 6.3121 -0.9009 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5682 6.5467 -1.9836 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9412 5.1027 -2.6475 N 0 0 3 0 0 0 0 0 0 0 0 0 9.2676 7.8261 -2.2358 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3898 7.4745 0.0251 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0397 9.0552 0.1412 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1627 10.4858 0.2841 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6643 9.4614 0.1407 N 0 0 3 0 0 0 0 0 0 0 0 0 4.3398 10.6433 0.3445 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7680 10.5498 2.1105 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9451 10.7073 2.1708 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1816 10.8767 0.9288 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1697 10.6590 3.6045 O 0 0 0 0 0 0 0 0 0 0 0 0 8.7967 11.0989 0.2731 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2872 11.7529 0.3625 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8930 13.5334 0.5228 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5383 1.9514 -0.6549 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9388 0.6212 0.3192 Br 0 0 0 0 0 0 0 0 0 0 0 0 4.7366 4.1118 0.5442 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5956 0.0000 -2.0022 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6821 1.7012 -3.2828 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8229 4.9299 -3.4099 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2822 7.1726 0.6601 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5626 8.7031 0.0595 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9798 11.8068 -0.1750 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7886 9.6601 -0.3504 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1280 9.3863 2.6300 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3192 11.5330 2.8054 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.7651 3.5819 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9222 11.7724 0.3055 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8296 13.8578 1.8050 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8376 14.2494 -0.0673 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7269 13.7810 -0.0533 H 0 0 0 0 0 0 0 0 0 0 0 0 1 22 1 0 0 0 0 1 5 2 0 0 0 0 1 24 1 0 0 0 0 2 22 2 0 0 0 0 2 3 1 0 0 0 0 2 25 1 0 0 0 0 3 4 2 0 0 0 0 3 26 1 0 0 0 0 4 8 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 6 10 2 0 0 0 0 7 8 1 0 0 0 0 7 9 2 0 0 0 0 8 27 1 0 0 0 0 10 11 1 0 0 0 0 10 28 1 0 0 0 0 11 12 2 0 0 0 0 11 13 1 0 0 0 0 12 20 1 0 0 0 0 12 14 1 0 0 0 0 13 19 1 0 0 0 0 13 29 1 0 0 0 0 14 15 1 0 0 0 0 14 30 1 0 0 0 0 14 31 1 0 0 0 0 15 16 1 0 0 0 0 15 32 1 0 0 0 0 15 33 1 0 0 0 0 16 18 1 0 0 0 0 16 17 2 0 0 0 0 18 34 1 0 0 0 0 19 20 2 0 0 0 0 19 35 1 0 0 0 0 20 21 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 M END > (256) 254 > (256) C17H15BrN2O3 > (256) 375.2211 > (256) FGFR-P254 > (256) 3-substituted indolin-2-one 9b > (256) FGFR-1 Tyrosine Kinase > (256) 80 > (256) BINDDB > (256) <2007 > (256) P > (256) TRAIN $$$$ 3-substituted indolin-2-one 9d csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 5.9398 10.5649 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6230 9.1072 -0.5140 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5935 10.6509 -0.4631 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2400 11.3786 -0.1836 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5696 12.9919 -0.1991 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1728 13.0965 -0.5018 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7093 11.7073 -0.6449 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8908 14.2422 -0.6058 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5817 14.1508 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1133 15.6227 0.1442 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3909 16.8978 -0.3404 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4435 16.0591 0.7723 N 0 0 3 0 0 0 0 0 0 0 0 0 4.8943 16.9705 -1.0947 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6731 17.1344 0.0813 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1765 17.2071 -0.6730 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0949 17.1353 -2.0137 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9340 17.3517 0.1444 O 0 0 0 0 0 0 0 0 0 0 0 0 8.5507 17.5627 0.6773 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3122 18.1016 0.0024 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9862 19.7157 -0.3174 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9786 9.0328 -0.0118 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3202 8.2991 -0.2892 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3573 6.6496 -0.3452 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0558 5.8344 -0.1280 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0977 4.2943 -0.1822 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4343 3.5664 -0.4524 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7259 4.3744 -0.6673 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6933 5.9102 -0.6216 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8307 3.4952 0.0295 O 0 0 0 0 0 0 0 0 0 0 0 0 4.9557 1.9110 -0.0414 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4266 1.2084 0.2220 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9035 11.1338 0.2599 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6571 8.5327 -0.7284 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7433 11.4720 -0.8484 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4029 13.9288 0.1032 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1799 15.4013 1.2097 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8649 17.9246 -1.8440 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7111 15.9525 -1.7291 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7025 16.1803 0.8304 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8563 18.1525 0.7154 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.3934 -0.3892 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4721 18.2239 1.0768 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3983 20.2042 0.6252 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0281 20.3112 -0.4967 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2960 19.7997 -1.3120 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9716 8.3994 0.1620 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0171 6.4020 0.0824 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4647 2.3653 -0.4943 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7627 3.8027 -0.8767 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7035 6.5386 -0.7950 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3668 1.5863 -1.1359 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7292 1.5276 0.8112 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5219 0.0000 0.1679 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0155 1.5331 1.3165 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6530 1.5917 -0.6307 H 0 0 0 0 0 0 0 0 0 0 0 0 1 21 1 0 0 0 0 1 4 2 0 0 0 0 1 32 1 0 0 0 0 2 22 1 0 0 0 0 2 3 2 0 0 0 0 2 33 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 34 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 19 1 0 0 0 0 11 13 1 0 0 0 0 12 18 1 0 0 0 0 12 36 1 0 0 0 0 13 14 1 0 0 0 0 13 37 1 0 0 0 0 13 38 1 0 0 0 0 14 15 1 0 0 0 0 14 39 1 0 0 0 0 14 40 1 0 0 0 0 15 17 1 0 0 0 0 15 16 2 0 0 0 0 17 41 1 0 0 0 0 18 19 2 0 0 0 0 18 42 1 0 0 0 0 19 20 1 0 0 0 0 20 43 1 0 0 0 0 20 44 1 0 0 0 0 20 45 1 0 0 0 0 21 22 2 0 0 0 0 21 46 1 0 0 0 0 22 23 1 0 0 0 0 23 28 2 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 25 29 1 0 0 0 0 26 27 2 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 29 30 1 0 0 0 0 30 31 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > (258) 256 > (258) C25H24N2O4 > (258) 416.4756 > (258) FGFR-P256 > (258) 3-substituted indolin-2-one 9d > (258) FGFR-1 Tyrosine Kinase > (258) 4500 > (258) BINDDB > (258) <2007 > (258) P > (258) TRAIN $$$$ 4-Anilinoquinazoline deriv. 26 csChFnd70/04170815452D 57 60 0 0 0 0 0 0 0 0999 V2000 5.0134 13.9044 0.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6899 13.8758 0.3155 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4732 11.4961 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0227 12.2625 0.1489 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6520 11.3941 0.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7232 9.8112 0.0834 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1545 9.0447 0.1895 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5189 9.8719 0.2758 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3622 14.6414 0.2166 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7694 12.3559 0.3359 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6389 16.3365 0.1537 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4531 18.8012 -0.3751 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4484 17.2019 -0.5079 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8246 17.0808 0.9504 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6406 19.5386 0.4148 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2893 16.4817 -1.2795 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6378 14.7175 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6706 14.1671 -0.1455 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1956 7.4690 0.2078 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3915 8.9691 0.0006 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9703 9.8166 -0.1051 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6886 6.7561 0.3176 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8227 18.6785 1.0791 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6437 21.5462 0.5790 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.5025 4.9905 0.3222 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1010 4.2272 0.4398 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6106 3.7641 -0.9316 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5120 1.7044 0.6361 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9091 2.4673 0.5901 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0406 4.5882 -1.0243 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3643 2.0840 -0.7897 N 0 0 3 0 0 0 0 0 0 0 0 0 11.8446 1.2414 -0.8591 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7556 14.5317 0.3816 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5439 11.9735 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6162 9.2723 0.3577 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5293 19.4749 -0.8883 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7478 16.4111 1.4698 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9838 10.5344 -1.1463 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.0074 -0.1635 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8427 10.5547 0.9141 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3953 7.1029 -0.6723 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2534 7.1232 1.3881 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7452 19.2573 1.6994 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7959 4.6436 1.3121 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9377 4.6233 -0.7483 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7093 4.6742 1.4545 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2758 4.0053 -1.9799 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2478 4.1832 0.0774 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1543 2.1334 1.6377 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3793 0.4500 0.7264 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2837 2.2004 1.6565 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2602 2.0270 -0.4022 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4095 4.1813 -2.0422 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2236 5.8369 -1.1115 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5916 1.6232 0.0873 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6285 0.0000 -0.7513 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4118 1.4762 -1.9650 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 35 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 36 1 0 0 0 0 13 16 1 0 0 0 0 14 23 2 0 0 0 0 14 37 1 0 0 0 0 15 23 1 0 0 0 0 15 24 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 22 25 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 43 1 0 0 0 0 25 26 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 29 1 0 0 0 0 26 30 1 0 0 0 0 26 46 1 0 0 0 0 27 31 1 0 0 0 0 27 30 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 28 31 1 0 0 0 0 28 29 1 0 0 0 0 28 49 1 0 0 0 0 28 50 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 32 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 32 57 1 0 0 0 0 M END > (261) 259 > (261) C23H26ClFN4O2 > (261) 444.9354 > (261) FGFR-P259 > (261) 4-Anilinoquinazoline 26 > (261) FGFR-1 Tyrosine Kinase > (261) 4100 > (261) BINDDB > (261) <2007 > (261) P > (261) TRAIN $$$$ 4-Anilinoquinazoline deriv. 10 csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 5.1436 15.5460 0.1350 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8899 15.5166 0.3237 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6414 13.0751 0.2629 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1533 13.8613 0.1527 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7469 12.9704 0.0646 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8200 11.3462 0.0856 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2884 10.5598 0.1950 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6882 11.4085 0.2836 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5276 16.3021 0.2223 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9715 13.9571 0.3451 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7335 18.0413 0.1577 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5168 20.5701 -0.3849 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5119 18.9293 -0.5211 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9501 18.8050 0.9752 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9481 20.4443 1.1072 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7352 21.3267 0.4256 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3228 18.1904 -1.3128 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7324 16.3802 0.0230 N 0 0 3 0 0 0 0 0 0 0 0 0 2.7400 15.8155 -0.1492 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4536 10.4821 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9954 11.3518 -0.1089 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3305 8.9432 0.2143 O 0 0 0 0 0 0 0 0 0 0 0 0 6.8624 8.2117 0.3275 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7378 23.3865 0.5953 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.6743 6.4274 0.3326 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6058 5.5425 -0.5514 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4177 3.7583 -0.5463 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2784 1.4409 -2.2641 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3985 3.8682 -3.2646 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7090 2.5452 -4.5113 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5958 1.0211 -3.4740 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1843 3.1920 -2.1844 N 0 0 0 0 0 0 0 0 0 0 0 0 8.9833 16.1896 0.3916 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6100 13.5649 -0.0190 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8143 10.7934 0.3675 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5690 21.2613 -0.9113 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8972 18.1179 1.5080 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8946 21.0381 1.7435 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0098 12.0884 -1.1772 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.5214 -0.1693 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8642 12.1092 0.9367 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5878 8.5673 -0.6881 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4418 8.5887 1.4258 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7714 5.8782 1.0652 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5086 6.0916 -1.2840 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4841 3.2124 -0.0476 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3883 3.4339 0.1743 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1426 0.9554 -2.6620 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5820 0.9616 -1.0969 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4863 4.1366 -2.6100 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9432 4.9366 -3.8436 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7944 2.5500 -5.4319 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8913 2.6658 -5.0326 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7203 0.7942 -2.8677 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2478 0.0000 -4.1954 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 22 1 0 0 0 0 8 35 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 36 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 16 1 0 0 0 0 15 38 1 0 0 0 0 16 24 1 0 0 0 0 18 19 1 0 0 0 0 20 21 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 23 25 1 0 0 0 0 23 42 1 0 0 0 0 23 43 1 0 0 0 0 25 26 2 0 0 0 0 25 44 1 0 0 0 0 26 27 1 0 0 0 0 26 45 1 0 0 0 0 27 32 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 32 1 0 0 0 0 28 31 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 32 1 0 0 0 0 29 30 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 31 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > (262) 260 > (262) C23H24ClFN4O2 > (262) 442.9196 > (262) FGFR-P260 > (262) 4-Anilinoquinazoline 10 > (262) FGFR-1 Tyrosine Kinase > (262) 1900 > (262) BINDDB > (262) <2007 > (262) P > (262) TRAIN $$$$ 4-Anilinoquinazoline deriv. 11 csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 4.5013 13.1323 0.1227 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9640 13.0849 0.5638 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8982 10.9100 -0.0287 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5469 11.6250 -0.1448 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3056 10.8388 -0.5158 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4067 9.3852 -0.7637 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7404 8.6703 -0.6504 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9767 9.4187 -0.2867 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7256 13.7981 0.4680 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0713 11.6890 0.3284 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2193 15.4003 0.1434 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9511 17.6227 0.5947 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9456 16.1309 0.4740 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4930 16.1713 -0.0588 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4913 17.6613 0.0633 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2220 18.3868 0.3872 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7048 15.3845 0.6765 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2184 13.8906 0.0209 N 0 0 3 0 0 0 0 0 0 0 0 0 2.3161 13.3773 -0.1356 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2006 8.6229 -1.1240 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8742 9.4121 -1.2220 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8135 7.2235 -0.9017 O 0 0 0 0 0 0 0 0 0 0 0 0 6.2028 6.5574 -0.7692 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0732 4.9625 -1.0848 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0223 4.3265 -1.9241 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8928 2.7315 -2.2395 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9900 0.9540 -4.1690 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0451 3.2963 -4.5339 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4792 2.3283 -5.8320 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3091 0.7904 -5.1800 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8569 2.5037 -3.8126 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2257 20.4264 0.5535 Br 0 0 0 0 0 0 0 0 0 0 0 0 7.9296 13.6786 0.8491 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2731 11.3793 -0.6051 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9996 8.8595 -0.2017 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9628 18.1915 0.8512 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4847 15.6065 -0.3108 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4821 18.2608 -0.0939 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.6769 -1.5165 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6350 9.9098 -0.1795 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9759 10.2515 -2.0443 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9503 7.0505 -1.5371 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6089 6.7094 0.3278 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1978 4.3437 -0.6188 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8978 4.9451 -2.3900 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8194 2.1635 -1.7809 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8991 2.3152 -1.7592 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0144 0.5837 -4.7192 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1597 0.3287 -3.1834 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9568 3.4288 -3.7974 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6665 4.3470 -4.9137 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7439 2.4855 -6.7409 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5959 2.5294 -6.1543 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2702 0.4891 -4.5661 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0896 0.0000 -6.0277 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 22 1 0 0 0 0 8 35 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 36 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 16 1 0 0 0 0 15 38 1 0 0 0 0 16 32 1 0 0 0 0 18 19 1 0 0 0 0 20 21 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 23 43 1 0 0 0 0 24 25 2 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 26 31 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 31 1 0 0 0 0 27 30 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 31 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 29 30 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 30 54 1 0 0 0 0 30 55 1 0 0 0 0 M END > (263) 261 > (263) C23H24BrFN4O2 > (263) 487.3706 > (263) FGFR-P261 > (263) 4-Anilinoquinazoline 11 > (263) FGFR-1 Tyrosine Kinase > (263) 2100 > (263) BINDDB > (263) <2007 > (263) P > (263) TRAIN $$$$ 4-Anilinoquinazoline deriv. 15 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 4.4755 12.7398 0.1220 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9241 12.6926 0.5606 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8644 10.5303 -0.0285 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5208 11.2411 -0.1439 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2866 10.4595 -0.5128 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3871 9.0140 -0.7593 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7132 8.3033 -0.6467 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9424 9.0473 -0.2850 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6928 13.4017 0.4654 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0307 11.3047 0.3266 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2009 14.9950 0.1426 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9397 17.2044 0.5913 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9345 15.7213 0.4713 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4673 15.7615 -0.0584 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4656 17.2428 0.0629 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2034 17.9644 0.3845 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7009 14.9791 0.6726 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2000 13.4937 0.0208 N 0 0 3 0 0 0 0 0 0 0 0 0 2.3030 12.9834 -0.1348 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7859 6.8648 -0.8964 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2068 19.8262 0.5358 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.1880 8.2561 -1.1176 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8692 9.0407 -1.2148 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1672 6.2024 -0.7647 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0364 4.5925 -1.0832 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6066 4.3760 -2.6589 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5414 2.7639 -2.9882 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3664 2.2608 -1.1951 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4862 3.8580 -0.8124 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9538 2.1111 -2.7131 N 0 0 3 0 0 0 0 0 0 0 0 0 6.9735 0.5946 -3.1586 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8842 13.2829 0.8442 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2601 10.9968 -0.6016 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9596 8.4917 -0.2012 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9571 17.7700 0.8465 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4533 15.1998 -0.3090 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4510 17.8388 -0.0931 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9703 9.8755 -2.0326 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.3098 -1.5077 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6314 9.5357 -0.1784 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9104 6.6927 -1.5283 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5709 6.3536 0.3259 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2211 4.1198 -0.3850 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5536 4.8570 -2.8473 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4008 4.8860 -3.3551 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7363 2.2572 -2.3020 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2506 2.6062 -4.1135 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4014 1.7380 -1.0181 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5529 1.7565 -0.5175 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3101 4.3598 -1.4795 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7761 3.9689 0.3186 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7423 0.5212 -4.3060 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0320 0.1375 -2.9428 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1608 0.0000 -2.5572 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 22 1 0 0 0 0 7 8 2 0 0 0 0 7 20 1 0 0 0 0 8 34 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 35 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 36 1 0 0 0 0 15 16 1 0 0 0 0 15 37 1 0 0 0 0 16 21 1 0 0 0 0 18 19 1 0 0 0 0 20 24 1 0 0 0 0 22 23 1 0 0 0 0 23 38 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 24 25 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 26 27 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 27 30 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 30 1 0 0 0 0 28 29 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 M END > (265) 263 > (265) C22H24ClFN4O2 > (265) 430.9086 > (265) FGFR-P263 > (265) 4-Anilinoquinazoline 15 > (265) FGFR-1 Tyrosine Kinase > (265) 4300 > (265) BINDDB > (265) <2007 > (265) P > (265) TRAIN $$$$ 4-Anilinoquinazoline deriv. 17 csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 4.4162 12.5700 0.1204 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8325 12.5234 0.5539 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7870 10.3898 -0.0289 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4610 11.0912 -0.1428 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2432 10.3199 -0.5077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3425 8.8939 -0.7516 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6513 8.1923 -0.6408 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8641 8.9265 -0.2832 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6174 13.2232 0.4600 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9378 11.1538 0.3224 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1582 14.7955 0.1407 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9105 16.9754 0.5858 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9087 15.5115 0.4672 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4076 15.5513 -0.0598 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1542 17.7291 0.3810 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6928 14.7771 0.6680 F 0 0 0 0 0 0 0 0 0 0 0 0 3.1574 13.3141 0.0205 N 0 0 3 0 0 0 0 0 0 0 0 0 2.2722 12.8104 -0.1332 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7233 6.7731 -0.8886 O 0 0 0 0 0 0 0 0 0 0 0 0 2.1591 8.1458 -1.1054 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8577 8.9201 -1.2010 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0865 6.1194 -0.7590 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9576 4.5310 -1.0746 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5337 4.3186 -2.6298 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4696 2.7278 -2.9562 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2705 2.2302 -1.1868 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3884 3.8061 -0.8078 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8635 2.0837 -2.6849 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8831 0.5875 -3.1258 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1525 19.5664 0.5315 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.4053 17.0179 0.0604 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6281 17.7602 -0.1352 O 0 0 0 0 0 0 0 0 0 0 0 0 7.7796 13.1059 0.8345 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2301 10.8503 -0.5953 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8678 8.3780 -0.1998 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9394 17.5305 0.8387 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3804 14.9972 -0.3088 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6229 9.4079 -0.1779 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9574 9.7443 -2.0076 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.1988 -1.4903 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8198 6.6041 -1.5119 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4848 6.2678 0.3176 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1530 4.0638 -0.3861 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4944 4.7933 -2.8153 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3175 4.8226 -3.3164 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6751 2.2271 -2.2795 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1827 2.5732 -4.0668 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2918 1.7142 -1.0124 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4676 1.7318 -0.5185 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2014 4.3020 -1.4656 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6743 3.9147 0.3085 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6552 0.5160 -4.2584 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9276 0.1363 -2.9132 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0812 0.0000 -2.5330 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7901 18.0497 -1.1069 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 35 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 36 1 0 0 0 0 13 16 1 0 0 0 0 14 31 2 0 0 0 0 14 37 1 0 0 0 0 15 31 1 0 0 0 0 15 30 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 28 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 29 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 31 32 1 0 0 0 0 32 55 1 0 0 0 0 M END > (267) 265 > (267) C22H24ClFN4O3 > (267) 446.908 > (267) FGFR-P265 > (267) 4-Anilinoquinazoline 17 > (267) FGFR-1 Tyrosine Kinase > (267) 900 > (267) BINDDB > (267) <2007 > (267) P > (267) TRAIN $$$$ 4-Anilinoquinazoline deriv. 18 csChFnd70/04170815452D 58 61 0 0 0 0 0 0 0 0999 V2000 4.5017 12.8142 0.1228 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9649 12.7666 0.5647 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8991 10.5917 -0.0294 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5474 11.3066 -0.1456 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3060 10.5204 -0.5175 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4073 9.0666 -0.7663 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7414 8.3518 -0.6534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9779 9.1001 -0.2892 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7261 13.4799 0.4689 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0724 11.3707 0.3277 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2193 15.0821 0.1433 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9480 17.3043 0.5977 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9456 15.8123 0.4764 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4926 15.8528 -0.0612 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2151 18.0722 0.3888 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7059 15.0640 0.6810 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2184 13.5728 0.0209 N 0 0 3 0 0 0 0 0 0 0 0 0 2.3162 13.0593 -0.1357 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8147 6.9048 -0.9055 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2011 8.3042 -1.1271 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8743 9.0935 -1.2245 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2045 6.2384 -0.7734 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0729 4.6191 -1.0947 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6405 4.4021 -2.6800 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5750 2.7806 -3.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4112 2.2739 -1.2086 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5315 3.8803 -0.8227 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9961 2.1239 -2.7355 N 0 0 3 0 0 0 0 0 0 0 0 0 7.0160 0.5986 -3.1844 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4896 17.3480 0.0616 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7355 18.1051 -0.1383 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2133 19.6981 0.5214 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9306 13.3605 0.8500 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2734 11.0611 -0.6069 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0012 8.5410 -0.2046 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9584 17.8705 0.8563 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4843 15.2882 -0.3151 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9760 9.9336 -2.0466 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.3583 -1.5195 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6351 9.5907 -0.1815 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9519 6.7324 -1.5412 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6106 6.3901 0.3239 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2528 4.1431 -0.3925 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5812 4.8860 -2.8690 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4395 4.9157 -3.3799 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7653 2.2704 -2.3220 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2824 2.6225 -4.1441 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4523 1.7478 -1.0308 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5928 1.7660 -0.5271 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3602 4.3856 -1.4935 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8232 3.9912 0.3152 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7835 0.5253 -4.3389 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0807 0.1388 -2.9679 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1985 0.0000 -2.5800 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9001 18.4003 -1.1290 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4451 20.0020 1.6378 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0391 20.1515 -0.1890 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1548 20.1168 0.2116 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 35 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 36 1 0 0 0 0 13 16 1 0 0 0 0 14 30 2 0 0 0 0 14 37 1 0 0 0 0 15 30 1 0 0 0 0 15 32 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 28 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 29 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 31 55 1 0 0 0 0 32 56 1 0 0 0 0 32 57 1 0 0 0 0 32 58 1 0 0 0 0 M END > (268) 266 > (268) C23H27FN4O3 > (268) 426.4897 > (268) FGFR-P266 > (268) 4-Anilinoquinazoline 18 > (268) FGFR-1 Tyrosine Kinase > (268) 1500 > (268) BINDDB > (268) <2007 > (268) P > (268) TRAIN $$$$ 4-Anilinoquinazoline deriv. 19 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 5.4418 15.4652 0.1474 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4070 15.4144 0.6387 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1129 12.7890 0.0036 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4894 13.6473 -0.1334 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9908 12.6961 -0.5375 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1053 10.9434 -0.7973 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7078 10.0848 -0.6631 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2000 10.9906 -0.2666 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9195 16.2713 0.5243 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5292 13.7314 0.3919 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9023 18.1914 0.1724 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2461 21.0093 -1.1249 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2460 19.2173 -1.2750 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5524 18.9710 1.7646 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9046 21.7809 0.4637 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5801 18.4649 -2.8265 F 0 0 0 0 0 0 0 0 0 0 0 0 3.9012 16.3760 0.0251 N 0 0 3 0 0 0 0 0 0 0 0 0 2.8174 15.7593 -0.1629 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7886 8.3404 -0.9265 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6493 10.0209 -1.1897 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0562 10.9691 -1.3074 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4582 7.5406 -0.7717 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2918 5.5876 -1.1101 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7466 5.2841 -3.0003 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6592 3.3279 -3.3526 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8922 2.7653 -1.2027 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0462 4.7045 -0.7862 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3686 2.5438 -3.0253 N 0 0 3 0 0 0 0 0 0 0 0 0 8.3822 0.6998 -3.5220 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5546 20.7638 1.9055 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2100 17.9788 3.1730 F 0 0 0 0 0 0 0 0 0 0 0 0 3.9054 24.0303 0.6462 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.5727 16.1331 0.9487 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7504 13.3452 -0.6430 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4289 10.3192 -0.1657 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5130 21.8070 -2.2491 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7866 11.5957 -0.0654 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1669 11.9547 -2.3197 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.0803 -1.6271 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3445 8.1103 -1.7193 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9639 7.7522 0.5349 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3172 5.0378 -0.2406 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4723 5.8625 -3.2238 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6958 5.8792 -3.8678 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6968 2.7366 -2.4971 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2894 3.1074 -4.7026 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1440 2.1361 -0.9914 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9193 2.1765 -0.3572 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0316 5.2905 -1.6190 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4150 4.8688 0.5720 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0843 0.5802 -4.9021 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6633 0.1511 -3.2660 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4090 0.0000 -2.7663 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2824 21.3702 3.1423 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 35 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 36 1 0 0 0 0 13 16 1 0 0 0 0 14 30 2 0 0 0 0 14 31 1 0 0 0 0 15 30 1 0 0 0 0 15 32 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 22 23 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 28 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 29 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 30 54 1 0 0 0 0 M END > (269) 267 > (269) C22H23ClF2N4O2 > (269) 448.8991 > (269) FGFR-P267 > (269) 4-Anilinoquinazoline 19 > (269) FGFR-1 Tyrosine Kinase > (269) 1700 > (269) BINDDB > (269) <2007 > (269) P > (269) TRAIN $$$$ 4-Anilinoquinazoline deriv. 20 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 5.4414 15.4631 0.1474 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4063 15.4124 0.6388 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1124 12.7872 0.0035 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4889 13.6456 -0.1336 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9906 12.6945 -0.5379 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1051 10.9420 -0.7977 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7074 10.0836 -0.6641 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1997 10.9894 -0.2682 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9189 16.2692 0.5244 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5286 13.7296 0.3919 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9020 18.1891 0.1724 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2454 21.0067 -1.1247 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2460 19.2148 -1.2748 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5516 18.9686 1.7643 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9030 21.7780 0.4634 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5810 18.4627 -2.8259 F 0 0 0 0 0 0 0 0 0 0 0 0 3.9009 16.3739 0.0251 N 0 0 3 0 0 0 0 0 0 0 0 0 2.8172 15.7572 -0.1629 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7883 8.3393 -0.9277 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6493 10.0195 -1.1896 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0561 10.9675 -1.3069 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4579 7.5398 -0.7734 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2915 5.5870 -1.1119 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7458 5.2836 -3.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6584 3.3277 -3.3542 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8919 2.7650 -1.2054 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0458 4.7040 -0.7888 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3679 2.5436 -3.0274 N 0 0 3 0 0 0 0 0 0 0 0 0 8.3813 0.6999 -3.5242 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5533 20.7611 1.9050 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2095 17.9767 3.1726 F 0 0 0 0 0 0 0 0 0 0 0 0 3.9037 24.2280 0.6620 Br 0 0 0 0 0 0 0 0 0 0 0 0 9.5718 16.1310 0.9489 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7502 13.3436 -0.6433 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4286 10.3180 -0.1678 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5130 21.8044 -2.2484 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7871 11.5941 -0.0649 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1664 11.9531 -2.3188 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.0788 -1.6261 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3439 8.1095 -1.7212 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9640 7.7512 0.5329 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3174 5.0370 -0.2423 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4716 5.8617 -3.2247 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6946 5.8788 -3.8695 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6963 2.7362 -2.4984 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2882 3.1072 -4.7040 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1438 2.1360 -0.9944 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9194 2.1763 -0.3597 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0308 5.2901 -1.6217 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4151 4.8683 0.5693 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0830 0.5804 -4.9042 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6624 0.1513 -3.2688 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4086 0.0000 -2.7683 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2808 21.3677 3.1414 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 35 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 36 1 0 0 0 0 13 16 1 0 0 0 0 14 30 2 0 0 0 0 14 31 1 0 0 0 0 15 30 1 0 0 0 0 15 32 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 22 23 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 28 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 29 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 30 54 1 0 0 0 0 M END > (270) 268 > (270) C22H23BrF2N4O2 > (270) 493.3501 > (270) FGFR-P268 > (270) 4-Anilinoquinazoline 20 > (270) FGFR-1 Tyrosine Kinase > (270) 1500 > (270) BINDDB > (270) <2007 > (270) P > (270) TRAIN $$$$ 4-Anilinoquinazoline deriv. 21 csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 4.8010 12.5048 0.1260 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3642 12.4774 0.3021 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1990 10.1985 0.2454 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8100 10.9324 0.1426 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4973 10.1009 0.0603 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5655 8.5849 0.0799 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9362 7.8509 0.1815 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2427 8.6431 0.2641 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0927 13.2106 0.2075 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4403 11.0218 0.3217 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4847 14.8339 0.1472 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3492 17.1942 -0.3592 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3446 15.6628 -0.4864 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6203 15.5467 0.9102 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4864 17.9004 0.3973 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2348 14.9730 -1.2253 F 0 0 0 0 0 0 0 0 0 0 0 0 3.4837 13.2836 0.0214 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5574 12.7564 -0.1393 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9755 6.3420 0.1990 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2902 7.7785 0.0006 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9292 8.5902 -0.1007 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4053 5.6593 0.3041 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2271 3.9684 0.3086 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6031 3.4586 -1.1901 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4909 1.7618 -1.2035 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5685 1.5471 0.4959 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7428 3.2376 0.5602 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9692 1.1157 -0.9591 N 0 0 3 0 0 0 0 0 0 0 0 0 4.6185 17.0768 1.0334 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4894 19.8230 0.5545 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.3847 13.1057 0.3655 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4361 10.6557 -0.0178 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2936 8.0689 0.3426 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4646 17.8394 -0.8507 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5043 14.9054 1.4076 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.8152 -0.1566 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8071 9.2970 0.8754 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9422 9.2776 -1.0978 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0820 5.9914 -0.6438 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9461 6.0109 1.3293 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4688 3.6436 1.1954 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5029 3.9379 -1.3542 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3402 3.8222 -2.0797 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7417 1.3999 -0.3233 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0619 1.3942 -2.2750 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6486 1.0236 0.6589 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8097 1.1862 1.3682 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5135 3.5977 -0.3020 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1713 3.5590 1.6465 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9431 0.0000 -1.0681 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5018 17.6310 1.6274 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 31 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 32 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 33 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 34 1 0 0 0 0 13 16 1 0 0 0 0 14 29 2 0 0 0 0 14 35 1 0 0 0 0 15 29 1 0 0 0 0 15 30 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 28 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > (271) 269 > (271) C21H22ClFN4O2 > (271) 416.8818 > (271) FGFR-P269 > (271) 4-Anilinoquinazoline 21 > (271) FGFR-1 Tyrosine Kinase > (271) 5000 > (271) BINDDB > (271) <2007 > (271) P > (271) TRAIN $$$$ 4-Anilinoquinazoline deriv. 22 csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 4.8016 12.5073 0.1260 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3652 12.4798 0.3022 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1998 10.2006 0.2454 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8106 10.9345 0.1426 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4977 10.1029 0.0603 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5660 8.5867 0.0799 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9368 7.8526 0.1820 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2435 8.6449 0.2647 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0936 13.2130 0.2075 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4414 11.0240 0.3222 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4851 14.8364 0.1473 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3496 17.1972 -0.3592 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3449 15.6656 -0.4865 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6209 15.5494 0.9103 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4868 17.9032 0.3973 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2347 14.9757 -1.2255 F 0 0 0 0 0 0 0 0 0 0 0 0 3.4842 13.2860 0.0214 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5576 12.7589 -0.1393 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9761 6.3434 0.2000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2904 7.7801 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9292 8.5920 -0.1017 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4061 5.6606 0.3057 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2277 3.9695 0.3106 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6040 3.4592 -1.1882 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4918 1.7621 -1.2012 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5694 1.5479 0.4991 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7437 3.2386 0.5628 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9702 1.1158 -0.9561 N 0 0 3 0 0 0 0 0 0 0 0 0 4.6190 17.0797 1.0335 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4901 19.9978 0.5686 Br 0 0 0 0 0 0 0 0 0 0 0 0 8.3859 13.1081 0.3655 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4364 10.6578 -0.0178 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2946 8.0706 0.3431 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4650 17.8425 -0.8510 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5051 14.9081 1.4078 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9427 9.2795 -1.0989 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.8168 -0.1580 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8068 9.2989 0.8744 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0832 5.9926 -0.6424 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9469 6.0126 1.3310 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4692 3.6450 1.1976 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5038 3.9385 -1.3527 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3414 3.8226 -2.0779 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7423 1.4005 -0.3209 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0629 1.3941 -2.2727 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6495 1.0244 0.6625 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8102 1.1873 1.3714 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5147 3.5985 -0.2994 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1721 3.5603 1.6493 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9441 0.0000 -1.0648 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5024 17.6342 1.6275 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 31 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 32 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 33 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 34 1 0 0 0 0 13 16 1 0 0 0 0 14 29 2 0 0 0 0 14 35 1 0 0 0 0 15 29 1 0 0 0 0 15 30 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 28 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > (272) 270 > (272) C21H22BrFN4O2 > (272) 461.3328 > (272) FGFR-P270 > (272) 4-Anilinoquinazoline 22 > (272) FGFR-1 Tyrosine Kinase > (272) 6000 > (272) BINDDB > (272) <2007 > (272) P > (272) TRAIN $$$$ 4-Anilinoquinazoline deriv. 24 csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 5.4402 14.1845 0.1474 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4045 14.1338 0.6385 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1108 11.5091 0.0036 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4876 12.3673 -0.1333 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9896 11.4163 -0.5374 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1041 9.6642 -0.7971 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7060 8.8058 -0.6630 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1980 9.7116 -0.2672 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9174 14.9905 0.5242 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5267 12.4514 0.3913 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9011 16.9100 0.1723 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2449 19.7271 -1.1246 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2447 17.9355 -1.2746 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5514 17.6892 1.7641 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9034 20.4984 0.4636 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5787 17.1834 -2.8256 F 0 0 0 0 0 0 0 0 0 0 0 0 3.9001 15.0951 0.0251 N 0 0 3 0 0 0 0 0 0 0 0 0 2.8165 14.4785 -0.1628 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7867 7.0619 -0.9258 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6485 8.7420 -1.1895 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0560 9.6900 -1.3070 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4558 6.2623 -0.7709 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2894 4.3100 -1.1085 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7439 4.0058 -2.9980 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6565 2.0501 -3.3495 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8891 1.4883 -1.2006 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0431 3.4271 -0.7849 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3654 1.2663 -3.0223 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5536 19.4816 1.9049 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9042 22.7472 0.6461 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.2090 16.6976 3.1720 F 0 0 0 0 0 0 0 0 0 0 0 0 9.5698 14.8523 0.9485 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7495 12.0653 -0.6428 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4265 9.0403 -0.1664 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5117 20.5245 -2.2483 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1666 10.6752 -2.3189 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.8014 -1.6266 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7864 10.3164 -0.0654 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3417 6.8316 -1.7184 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9616 6.4743 0.5352 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3152 3.7606 -0.2390 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4701 4.5838 -3.2214 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6927 4.6004 -3.8656 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6945 1.4594 -2.4937 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2865 1.8293 -4.6989 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1407 0.8593 -0.9892 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9166 0.9001 -0.3549 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0283 4.0126 -1.6176 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4121 3.5919 0.5730 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3746 0.0000 -3.3629 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2814 20.0878 3.1413 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 34 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 35 1 0 0 0 0 13 16 1 0 0 0 0 14 29 2 0 0 0 0 14 31 1 0 0 0 0 15 29 1 0 0 0 0 15 30 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 28 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > (274) 272 > (274) C21H21ClF2N4O2 > (274) 434.8723 > (274) FGFR-P272 > (274) 4-Anilinoquinazoline 24 > (274) FGFR-1 Tyrosine Kinase > (274) 2500 > (274) BINDDB > (274) <2007 > (274) P > (274) TRAIN $$$$ 4-Anilinoquinazoline deriv. 25 csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 5.4406 14.1837 0.1474 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4049 14.1329 0.6387 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1112 11.5082 0.0035 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4881 12.3665 -0.1336 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9898 11.4155 -0.5378 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1045 9.6632 -0.7976 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7065 8.8049 -0.6640 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1985 9.7105 -0.2681 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9178 14.9895 0.5243 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5272 12.4504 0.3913 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9013 16.9091 0.1723 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2448 19.7263 -1.1245 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2454 17.9347 -1.2746 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5511 17.6886 1.7640 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9025 20.4975 0.4633 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5804 17.1828 -2.8255 F 0 0 0 0 0 0 0 0 0 0 0 0 3.9004 15.0942 0.0251 N 0 0 3 0 0 0 0 0 0 0 0 0 2.8168 14.4777 -0.1628 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7875 7.0609 -0.9276 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6488 8.7409 -1.1895 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0560 9.6887 -1.3066 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4567 6.2615 -0.7733 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2903 4.3091 -1.1117 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7447 4.0057 -3.0012 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6574 2.0501 -3.3537 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8904 1.4875 -1.2052 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0443 3.4262 -0.7886 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3666 1.2661 -3.0269 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5528 19.4808 1.9047 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9031 22.9472 0.6619 Br 0 0 0 0 0 0 0 0 0 0 0 0 3.2090 16.6967 3.1721 F 0 0 0 0 0 0 0 0 0 0 0 0 9.5703 14.8513 0.9488 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7497 12.0645 -0.6432 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4271 9.0393 -0.1673 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5124 20.5239 -2.2480 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7869 10.3151 -0.0649 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1662 10.6741 -2.3185 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.8001 -1.6259 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3425 6.8311 -1.7209 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9627 6.4729 0.5329 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3163 3.7592 -0.2423 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4708 4.5838 -3.2242 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6933 4.6008 -3.8688 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6956 1.4587 -2.4980 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2872 1.8297 -4.7033 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1422 0.8586 -0.9942 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9182 0.8989 -0.3596 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0292 4.0122 -1.6215 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4136 3.5904 0.5693 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3758 0.0000 -3.3681 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2802 20.0872 3.1409 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 34 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 35 1 0 0 0 0 13 16 1 0 0 0 0 14 29 2 0 0 0 0 14 31 1 0 0 0 0 15 29 1 0 0 0 0 15 30 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 28 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > (275) 273 > (275) C21H21BrF2N4O2 > (275) 479.3233 > (275) FGFR-P273 > (275) 4-Anilinoquinazoline 25 > (275) FGFR-1 Tyrosine Kinase > (275) 1900 > (275) BINDDB > (275) <2007 > (275) P > (275) TRAIN $$$$ 4-Anilinoquinazoline deriv. 27 csChFnd70/04170815452D 57 60 0 0 0 0 0 0 0 0999 V2000 5.0125 13.9027 0.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6886 13.8741 0.3154 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4720 11.4948 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0219 12.2610 0.1489 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6513 11.3928 0.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7226 9.8101 0.0834 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1535 9.0437 0.1900 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5176 9.8708 0.2764 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3612 14.6395 0.2166 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7680 12.3544 0.3363 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6381 16.3341 0.1537 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4527 18.7986 -0.3750 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4479 17.1998 -0.5078 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8238 17.0785 0.9503 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6400 19.5356 0.4148 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2890 16.4796 -1.2793 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6372 14.7157 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6699 14.1654 -0.1454 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1946 7.4682 0.2088 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3910 8.9680 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9700 9.8155 -0.1062 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6873 6.7554 0.3192 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8218 18.6760 1.0789 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5011 4.9902 0.3243 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0995 4.2270 0.4424 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6090 3.7635 -0.9281 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5102 1.7048 0.6397 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9075 2.4675 0.5932 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0391 4.5876 -1.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3626 2.0837 -0.7858 N 0 0 3 0 0 0 0 0 0 0 0 0 11.8426 1.2413 -0.8547 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6433 21.7222 0.5936 Br 0 0 0 0 0 0 0 0 0 0 0 0 8.7541 14.5299 0.3816 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5434 11.9721 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6149 9.2713 0.3581 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5294 19.4722 -0.8884 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7468 16.4090 1.4696 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.0063 -0.1650 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8422 10.5535 0.9128 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9841 10.5332 -1.1472 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3941 7.1020 -0.6706 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2519 7.1229 1.3894 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7441 19.2547 1.6990 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7945 4.6438 1.3140 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9367 4.6228 -0.7460 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7074 4.6744 1.4570 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2743 4.0044 -1.9763 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2458 4.1829 0.0806 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1521 2.1338 1.6413 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3773 0.4504 0.7305 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2819 2.2009 1.6595 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2588 2.0270 -0.3990 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4083 4.1805 -2.0391 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2221 5.8357 -1.1089 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5894 1.6232 0.0917 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6265 0.0000 -0.7465 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4099 1.4756 -1.9602 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 35 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 36 1 0 0 0 0 13 16 1 0 0 0 0 14 23 2 0 0 0 0 14 37 1 0 0 0 0 15 23 1 0 0 0 0 15 32 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 22 24 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 28 1 0 0 0 0 25 29 1 0 0 0 0 25 46 1 0 0 0 0 26 30 1 0 0 0 0 26 29 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 30 1 0 0 0 0 27 28 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 M END > (276) 274 > (276) C23H26BrFN4O2 > (276) 489.3864 > (276) FGFR-P274 > (276) 4-Anilinoquinazoline 27 > (276) FGFR-1 Tyrosine Kinase > (276) 2100 > (276) BINDDB > (276) <2007 > (276) P > (276) TRAIN $$$$ 4-Anilinoquinazoline deriv. 28 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 5.0127 13.4530 0.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6890 13.4243 0.3154 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4723 11.0449 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0221 11.8111 0.1489 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6514 10.9429 0.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7227 9.3601 0.0834 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1537 8.5937 0.1900 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5179 9.4209 0.2764 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3614 14.1897 0.2166 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7684 11.9045 0.3363 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6382 15.8845 0.1537 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4528 18.3490 -0.3750 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4480 16.7501 -0.5078 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8240 16.6288 0.9503 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6401 19.0861 0.4148 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2890 16.0299 -1.2793 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6373 14.2659 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6700 13.7156 -0.1454 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1948 7.0183 0.2088 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3911 8.5180 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9700 9.3656 -0.1062 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6877 6.3053 0.3192 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8220 18.2264 1.0789 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5014 4.5400 0.3243 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0999 3.7767 0.4424 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6095 3.3132 -0.9281 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5107 1.2544 0.6397 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9079 2.0172 0.5932 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0395 4.1373 -1.0215 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3631 1.6334 -0.7858 N 0 0 3 0 0 0 0 0 0 0 0 0 3.6434 21.2728 0.5936 Br 0 0 0 0 0 0 0 0 0 0 0 0 8.7545 14.0802 0.3816 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5435 11.5222 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6153 8.8213 0.3581 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5295 19.0227 -0.8884 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7470 15.9593 1.4697 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.5563 -0.1650 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8422 10.1036 0.9128 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9841 10.0833 -1.1472 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3945 6.6519 -0.6706 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2523 6.6729 1.3894 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7443 18.8052 1.6991 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7947 4.1935 1.3140 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9370 4.1725 -0.7460 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7078 4.2242 1.4571 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2748 3.5541 -1.9764 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2463 3.7326 0.0806 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1526 1.6835 1.6414 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3777 0.0000 0.7305 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2823 1.7506 1.6596 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2592 1.5767 -0.3990 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4087 3.7302 -2.0392 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2225 5.3857 -1.1089 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8142 1.2084 -1.7285 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 34 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 35 1 0 0 0 0 13 16 1 0 0 0 0 14 23 2 0 0 0 0 14 36 1 0 0 0 0 15 23 1 0 0 0 0 15 31 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 22 24 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 28 1 0 0 0 0 25 29 1 0 0 0 0 25 45 1 0 0 0 0 26 30 1 0 0 0 0 26 29 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 30 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 30 54 1 0 0 0 0 M END > (277) 275 > (277) C22H24BrFN4O2 > (277) 475.3596 > (277) FGFR-P275 > (277) 4-Anilinoquinazoline 28 > (277) FGFR-1 Tyrosine Kinase > (277) 2700 > (277) BINDDB > (277) <2007 > (277) P > (277) TRAIN $$$$ 4-Anilinoquinazoline deriv. 29 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 5.0211 13.1755 0.1318 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7019 13.1468 0.3160 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4833 10.7635 0.2566 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0305 11.5310 0.1491 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6576 10.6613 0.0631 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7290 9.0759 0.0836 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1625 8.3082 0.1898 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5291 9.1367 0.2762 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3722 13.9137 0.2170 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7815 11.6245 0.3364 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6445 15.6114 0.1540 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4569 18.0799 -0.3757 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4521 16.4782 -0.5087 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8321 16.3569 0.9519 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6462 18.8185 0.4155 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2914 15.7569 -1.2815 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6435 13.9900 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6747 13.4387 -0.1457 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2036 6.7301 0.2081 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3952 8.2326 0.0006 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9718 9.0814 -0.1053 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6991 6.0161 0.3181 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8302 17.9571 1.0808 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6494 20.8292 0.5799 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.5127 4.2477 0.3227 C 0 0 2 0 0 0 0 0 0 0 0 0 8.0990 3.4837 0.5801 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9133 1.7152 0.5136 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8518 3.7162 -1.2407 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2118 1.2572 -1.0554 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6956 2.0168 -1.2457 N 0 0 3 0 0 0 0 0 0 0 0 0 4.9154 1.4784 -2.6656 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7692 13.8038 0.3822 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5478 11.2416 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6281 8.5362 0.3583 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5317 18.7547 -0.8897 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7568 15.6861 1.4721 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.2709 -0.1637 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8441 9.8206 0.9155 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9854 9.8003 -1.1481 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4068 6.3635 -0.6734 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2647 6.3838 1.3903 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7541 18.5368 1.7020 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7229 3.9081 1.2530 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9017 3.8595 -0.3248 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5513 3.8194 1.7148 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0469 1.1656 0.6466 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1460 1.3351 1.4470 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7147 4.2451 -1.4200 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6338 4.0710 -2.1719 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9874 1.6235 -1.9875 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0627 0.0000 -1.1001 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6638 0.2409 -2.5658 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8333 2.1183 -2.8215 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6707 1.6765 -3.6633 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 34 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 35 1 0 0 0 0 13 16 1 0 0 0 0 14 23 2 0 0 0 0 14 36 1 0 0 0 0 15 23 1 0 0 0 0 15 24 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 22 25 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 42 1 0 0 0 0 25 28 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 26 27 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 27 29 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 30 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 30 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 M END > (278) 276 > (278) C22H24ClFN4O2 > (278) 430.9086 > (278) FGFR-P276 > (278) 4-Anilinoquinazoline 29 > (278) FGFR-1 Tyrosine Kinase > (278) 1800 > (278) BINDDB > (278) <2007 > (278) P > (278) TRAIN $$$$ 4-Anilinoquinazoline deriv. 30 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 5.0219 13.1782 0.1318 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7030 13.1495 0.3160 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4842 10.7656 0.2566 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0313 11.5332 0.1491 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6582 10.6635 0.0631 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7296 9.0778 0.0836 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1632 8.3100 0.1904 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5299 9.1386 0.2769 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3731 13.9162 0.2170 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7826 11.6268 0.3370 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6450 15.6141 0.1540 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4573 18.0832 -0.3757 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4524 16.4813 -0.5088 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8329 16.3598 0.9521 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6468 18.8216 0.4155 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2914 15.7598 -1.2817 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6440 13.9926 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6750 13.4413 -0.1456 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2043 6.7315 0.2092 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3955 8.2342 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9718 9.0833 -0.1064 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6999 6.0174 0.3198 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8309 17.9603 1.0809 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5134 4.2488 0.3249 C 0 0 2 0 0 0 0 0 0 0 0 0 8.1001 3.4848 0.5829 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9143 1.7158 0.5168 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8528 3.7168 -1.2387 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2130 1.2573 -1.0524 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6965 2.0170 -1.2434 N 0 0 3 0 0 0 0 0 0 0 0 0 4.9167 1.4781 -2.6635 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6502 21.0123 0.5947 Br 0 0 0 0 0 0 0 0 0 0 0 0 8.7706 13.8065 0.3823 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5481 11.2438 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6293 8.5380 0.3588 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5322 18.7582 -0.8900 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7576 15.6890 1.4723 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8437 9.8226 0.9145 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9859 9.8023 -1.1493 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.2725 -0.1653 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4080 6.3646 -0.6718 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2655 6.3855 1.3920 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7548 18.5402 1.7021 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7233 3.9095 1.2553 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9031 3.8603 -0.3222 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5522 3.8208 1.7177 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0479 1.1663 0.6503 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1466 1.3360 1.4504 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7157 4.2458 -1.4185 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6351 4.0713 -2.1701 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9891 1.6233 -1.9846 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0637 0.0000 -1.0968 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6648 0.2405 -2.5633 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8344 2.1180 -2.8198 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6721 1.6758 -3.6612 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 17 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 19 1 0 0 0 0 8 34 1 0 0 0 0 11 17 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 15 2 0 0 0 0 12 35 1 0 0 0 0 13 16 1 0 0 0 0 14 23 2 0 0 0 0 14 36 1 0 0 0 0 15 23 1 0 0 0 0 15 31 1 0 0 0 0 17 18 1 0 0 0 0 19 22 1 0 0 0 0 20 21 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 22 24 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 42 1 0 0 0 0 24 27 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 25 26 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 28 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 29 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 29 30 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 M END > (279) 277 > (279) C22H24BrFN4O2 > (279) 475.3596 > (279) FGFR-P277 > (279) 4-Anilinoquinazoline 30 > (279) FGFR-1 Tyrosine Kinase > (279) 1800 > (279) BINDDB > (279) <2007 > (279) P > (279) TRAIN $$$$ 4-Anilinoquinazoline deriv. 4 csChFnd70/04170815452D 59 62 0 0 0 0 0 0 0 0999 V2000 5.0134 16.6183 0.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6900 16.5896 0.3155 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4732 14.2099 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0228 14.9762 0.1489 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6520 14.1079 0.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7232 12.5249 0.0834 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1546 11.7584 0.1895 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5189 12.5856 0.2758 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3622 17.3552 0.2166 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7695 15.0696 0.3364 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6389 19.0502 0.1537 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4531 21.5149 -0.3751 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4484 19.9158 -0.5079 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8247 19.7946 0.9504 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8228 21.3923 1.0791 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6404 22.2523 0.4153 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2893 19.1956 -1.2795 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6378 17.4313 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6706 16.8810 -0.1454 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3915 11.6829 0.0006 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9703 12.5304 -0.1051 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6432 24.2600 0.5800 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.1956 10.1827 0.2078 O 0 0 0 0 0 0 0 0 0 0 0 0 6.6886 9.4698 0.3176 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5025 7.7043 0.3222 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1011 6.9409 0.4398 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6862 4.7644 1.5156 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4747 3.0038 1.4176 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1832 2.7165 0.7322 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3947 4.4770 0.8301 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9224 5.2458 0.4441 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9471 2.2351 1.8037 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7684 0.5399 1.8081 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7556 17.2455 0.3816 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5439 14.6873 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6164 11.9861 0.3573 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5296 22.1886 -0.8886 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7478 19.1248 1.4698 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7455 21.9711 1.6990 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.7212 -0.1635 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8427 13.2685 0.9141 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9838 13.2482 -1.1463 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3954 9.8166 -0.6723 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2534 9.8369 1.3881 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7959 7.3573 1.3121 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9377 7.3370 -0.7483 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8077 7.2878 -0.5502 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6659 7.3080 1.5102 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6048 5.3377 1.1970 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0027 5.0864 2.6970 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5816 2.6400 2.2359 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1274 2.6852 0.2440 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8667 2.3945 -0.4493 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2646 2.1432 1.0508 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7421 4.7958 2.0039 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2879 4.8410 0.0118 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3965 0.1522 0.6630 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8750 0.0000 2.0972 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9010 0.2097 2.6672 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 34 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 35 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 23 1 0 0 0 0 8 36 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 37 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 38 1 0 0 0 0 15 16 1 0 0 0 0 15 39 1 0 0 0 0 16 22 1 0 0 0 0 18 19 1 0 0 0 0 20 21 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 21 42 1 0 0 0 0 23 24 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 31 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 31 1 0 0 0 0 27 28 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 32 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 29 32 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 32 33 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > (280) 279 > (280) C23H27ClFN5O2 > (280) 459.95 > (280) FGFR-P279 > (280) 4-Anilinoquinazoline 4 > (280) FGFR-1 Tyrosine Kinase > (280) 2100 > (280) BINDDB > (280) <2007 > (280) P > (280) TRAIN $$$$ 4-Anilinoquinazoline deriv. 5 csChFnd70/04170815452D 59 62 0 0 0 0 0 0 0 0999 V2000 4.4755 15.4636 0.1220 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9241 15.4165 0.5606 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8644 13.2541 -0.0285 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5208 13.9649 -0.1440 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2866 13.1833 -0.5128 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3872 11.7380 -0.7593 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7132 11.0272 -0.6467 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9424 11.7713 -0.2850 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6928 16.1256 0.4654 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0307 14.0285 0.3266 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2008 17.7186 0.1426 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9400 19.9283 0.5913 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9345 18.4451 0.4713 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4672 18.4852 -0.0584 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4655 19.9667 0.0629 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2035 20.6879 0.3850 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7008 17.7029 0.6726 F 0 0 0 0 0 0 0 0 0 0 0 0 3.2000 16.2176 0.0208 N 0 0 3 0 0 0 0 0 0 0 0 0 2.3029 15.7072 -0.1348 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1880 10.9801 -1.1176 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8692 11.7647 -1.2149 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7859 9.5888 -0.8965 O 0 0 0 0 0 0 0 0 0 0 0 0 6.1672 8.9263 -0.7648 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0364 7.3163 -1.0832 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5154 6.6070 -0.9423 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1537 4.4321 -0.4888 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0097 2.8444 -0.9018 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5816 2.7123 -1.2910 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7256 4.3001 -0.8780 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3898 5.0613 -1.2481 N 0 0 0 0 0 0 0 0 0 0 0 0 7.3454 2.0832 -0.5318 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2197 0.5374 -0.8376 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2072 22.7159 0.5504 Br 0 0 0 0 0 0 0 0 0 0 0 0 7.8842 16.0068 0.8442 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2601 13.7207 -0.6017 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9595 11.2154 -0.2006 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9573 20.4938 0.8464 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4533 17.9236 -0.3090 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4507 20.5627 -0.0934 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9703 12.5994 -2.0326 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.0337 -1.5078 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6314 12.2596 -0.1785 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9104 9.4167 -1.5283 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5709 9.0775 0.3259 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2933 6.8259 -0.3198 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6326 7.1650 -2.1740 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2586 7.0974 -1.7057 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9192 6.7583 0.1485 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1759 5.0052 -0.7909 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3184 4.5219 0.6690 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1124 2.3675 -0.3161 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8156 2.7561 -2.0552 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4167 2.6226 -2.4487 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5594 2.1392 -0.9890 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9197 4.3883 0.2754 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6229 4.7769 -1.4637 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0018 0.3811 -1.9793 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2228 0.0000 -0.5539 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3413 0.0841 -0.2063 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 34 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 35 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 22 1 0 0 0 0 8 36 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 37 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 38 1 0 0 0 0 15 16 1 0 0 0 0 15 39 1 0 0 0 0 16 33 1 0 0 0 0 18 19 1 0 0 0 0 20 21 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 30 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 30 1 0 0 0 0 26 27 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 31 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 28 31 1 0 0 0 0 28 29 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 29 30 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 31 32 1 0 0 0 0 32 57 1 0 0 0 0 32 58 1 0 0 0 0 32 59 1 0 0 0 0 M END > (281) 280 > (281) C23H27BrFN5O2 > (281) 504.401 > (281) FGFR-P280 > (281) 4-Anilinoquinazoline 5 > (281) FGFR-1 Tyrosine Kinase > (281) 2000 > (281) BINDDB > (281) <2007 > (281) P > (281) TRAIN $$$$ 4-Anilinoquinazoline deriv. 6 csChFnd70/04170815452D 56 59 0 0 0 0 0 0 0 0999 V2000 5.5355 14.3655 -0.4986 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3871 14.2546 0.1578 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9965 11.6971 -0.0394 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4809 12.5754 -0.4268 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9859 11.6700 -0.7262 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9996 9.9425 -0.6423 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4947 9.0645 -0.2589 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9812 9.9255 0.0413 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0022 15.1284 -0.1996 N 0 0 0 0 0 0 0 0 0 0 0 0 8.4120 12.5956 0.2415 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1453 17.0626 -0.7961 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0385 19.7651 -1.6420 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9928 18.0163 -1.7255 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3336 17.8698 0.2177 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3729 19.6170 0.2958 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2294 20.5643 -0.6350 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8306 17.2357 -2.7088 F 0 0 0 0 0 0 0 0 0 0 0 0 4.1026 15.2924 -0.8767 N 0 0 3 0 0 0 0 0 0 0 0 0 3.0661 14.7169 -1.1985 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5471 9.0642 -0.9332 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0658 10.0303 -1.3169 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4763 7.3459 -0.1821 O 0 0 0 0 0 0 0 0 0 0 0 0 7.0394 6.5245 0.2141 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7715 4.6058 0.2433 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2832 22.7597 -0.5321 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.2186 1.7080 -3.2129 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2083 3.7030 -4.4201 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7537 4.2371 -2.6386 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7640 2.2422 -1.4313 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3271 4.0158 -1.4641 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6452 1.9295 -4.3873 N 0 0 0 0 0 0 0 0 0 0 0 0 6.2008 1.3394 -6.0948 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5487 14.9378 0.3903 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8275 12.3343 -1.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1272 9.2393 0.3357 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1443 20.5074 -2.3630 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2264 17.1321 0.9452 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2971 20.2447 1.0848 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7828 10.8767 -0.2639 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2846 10.7741 -2.4591 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.1770 -1.5207 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9821 6.8430 -0.7425 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4798 6.9465 1.4526 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9330 3.9853 0.6567 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7487 4.2972 1.1175 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8351 0.3821 -3.1989 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1581 2.4903 -3.6238 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1703 4.5079 -4.8448 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2752 3.8315 -5.2863 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8141 3.4549 -2.2277 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1371 5.5631 -2.6525 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6970 2.1136 -0.5651 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8020 1.4372 -1.0067 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1235 2.0626 -6.5657 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2788 1.5178 -6.9384 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8704 0.0000 -6.0472 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 33 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 22 1 0 0 0 0 8 35 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 36 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 16 1 0 0 0 0 15 38 1 0 0 0 0 16 25 1 0 0 0 0 18 19 1 0 0 0 0 20 21 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 23 43 1 0 0 0 0 24 30 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 26 31 1 0 0 0 0 26 29 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 31 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 30 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 29 30 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 31 32 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 32 56 1 0 0 0 0 M END > (282) 281 > (282) C22H25ClFN5O2 > (282) 445.9232 > (282) FGFR-P281 > (282) 4-Anilinoquinazoline 6 > (282) FGFR-1 Tyrosine Kinase > (282) 8000 > (282) BINDDB > (282) <2007 > (282) P > (282) TRAIN $$$$ 4-Anilinoquinazoline deriv. 9 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 4.4209 13.7936 -0.1805 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0067 14.0015 0.1162 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0352 11.5886 0.0605 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5700 12.2034 -0.1251 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3211 11.2413 -0.2484 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5249 9.7139 -0.1887 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9716 9.0972 -0.0046 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2179 10.0189 0.1198 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6599 14.6263 -0.0558 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2130 12.5358 0.1754 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8805 16.0317 -0.2770 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5302 18.3042 -0.8787 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6684 16.7514 -0.9693 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9443 16.8747 0.5077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7999 18.4254 0.5941 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5962 19.1404 -0.1003 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6280 15.9347 -1.7295 F 0 0 0 0 0 0 0 0 0 0 0 0 3.0242 14.4602 -0.3658 N 0 0 3 0 0 0 0 0 0 0 0 0 2.1422 13.8396 -0.5574 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3114 8.7807 -0.3085 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8674 9.4767 -0.4937 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1455 7.5743 0.0521 O 0 0 0 0 0 0 0 0 0 0 0 0 6.6475 7.0149 0.2413 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4191 21.0895 0.0121 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.6183 5.2878 0.2790 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2263 4.6890 0.4816 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1631 2.3683 1.4754 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0778 1.2592 2.4601 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4570 0.8789 1.4491 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7408 2.4082 0.6487 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2178 3.0339 0.3723 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9793 14.7310 0.2119 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2020 11.7051 -0.3897 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3282 9.5347 0.2614 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5894 18.8646 -1.4156 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8840 16.3182 1.0506 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6272 19.0809 1.2050 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.6071 -0.5746 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6337 10.2006 0.4741 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8669 10.1536 -1.5218 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3474 7.3930 -0.6979 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1137 7.4407 1.2979 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9184 4.9098 1.2184 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1521 4.8622 -0.7775 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9512 5.1546 -0.3974 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6532 5.0250 1.5862 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2671 1.7642 0.8861 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6805 3.2543 2.1805 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4400 1.8011 3.5042 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4210 0.2462 2.6993 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4275 0.5519 2.1317 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1771 0.0000 0.6340 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3871 3.1602 1.3779 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 2.2312 -0.4168 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 18 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 8 2 0 0 0 0 7 22 1 0 0 0 0 8 34 1 0 0 0 0 11 18 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 35 1 0 0 0 0 13 17 1 0 0 0 0 14 15 2 0 0 0 0 14 36 1 0 0 0 0 15 16 1 0 0 0 0 15 37 1 0 0 0 0 16 24 1 0 0 0 0 18 19 1 0 0 0 0 20 21 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 23 25 1 0 0 0 0 23 41 1 0 0 0 0 23 42 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 26 31 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 27 31 1 0 0 0 0 27 28 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 28 29 1 0 0 0 0 28 49 1 0 0 0 0 28 50 1 0 0 0 0 29 30 1 0 0 0 0 29 51 1 0 0 0 0 29 52 1 0 0 0 0 30 31 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 M END > (283) 282 > (283) C22H24ClFN4O2 > (283) 430.9086 > (283) FGFR-P282 > (283) 4-Anilinoquinazoline 9 > (283) FGFR-1 Tyrosine Kinase > (283) 4200 > (283) BINDDB > (283) <2007 > (283) P > (283) TRAIN $$$$ 1,6-naphthyridine 15 csChFnd70/04170815452D 64 67 0 0 0 0 0 0 0 0999 V2000 2.7554 18.9977 0.0127 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8959 18.9027 -0.0178 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3318 19.8646 0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4046 16.2914 -0.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7803 17.1696 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2445 16.1899 0.0107 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8111 13.6163 -0.0194 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3916 14.4674 -0.0266 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3151 14.4843 -0.0003 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8898 17.1907 -0.0269 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3786 21.7911 0.0116 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4229 24.5292 -1.1575 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4658 25.3979 0.0292 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3766 22.7290 -1.1702 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4190 22.6679 1.2069 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4593 24.4682 1.2124 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4736 25.3243 2.3779 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4527 27.1804 2.3105 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4456 25.4448 -2.3092 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5561 27.2970 -2.2237 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7823 11.8099 -0.0300 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4670 19.7773 -0.0287 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4159 10.8317 -0.0509 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0215 8.8827 -0.0593 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7275 7.8612 -0.0811 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0153 5.5557 1.2077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5843 3.6174 1.0874 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5061 3.0305 0.0795 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9371 4.9688 0.1999 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3488 5.9898 -0.0890 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1724 2.5965 1.3763 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7938 0.7251 1.3684 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5425 19.7039 0.0338 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.8390 0.0265 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5941 13.7433 -0.0425 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5000 26.8011 0.0361 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5650 22.0535 -2.0952 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1927 21.9450 2.1283 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8919 27.6117 1.0346 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1344 27.6464 2.5386 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3160 27.6989 3.3072 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7142 27.8665 -3.2107 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1440 27.7360 -0.9413 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8941 27.7014 -2.4538 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6807 11.1970 -0.0237 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5488 19.1300 -0.0429 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4868 21.0379 -0.0221 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1535 11.1693 -1.2125 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1746 11.1551 1.1009 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2838 8.5451 1.1023 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2626 8.5593 -1.2111 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4652 8.1986 -1.2425 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4863 8.1846 1.0707 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8466 6.3162 0.9565 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5028 5.8519 2.5045 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6227 3.2850 2.0732 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0636 3.3280 -0.1980 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0186 2.7343 -1.2172 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6747 2.2700 0.3307 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4578 5.2582 1.4852 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8986 5.3012 -0.7860 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2409 0.3605 0.1159 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9914 0.0000 1.5849 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8680 0.4263 2.3983 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 3 2 0 0 0 0 1 33 1 0 0 0 0 2 10 2 0 0 0 0 2 3 1 0 0 0 0 2 22 1 0 0 0 0 3 11 1 0 0 0 0 4 10 1 0 0 0 0 4 8 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 6 34 1 0 0 0 0 7 9 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 35 1 0 0 0 0 11 15 1 0 0 0 0 11 14 2 0 0 0 0 12 14 1 0 0 0 0 12 13 2 0 0 0 0 12 19 1 0 0 0 0 13 16 1 0 0 0 0 13 36 1 0 0 0 0 14 37 1 0 0 0 0 15 16 2 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 17 18 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 20 44 1 0 0 0 0 21 23 1 0 0 0 0 21 45 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 23 24 1 0 0 0 0 23 48 1 0 0 0 0 23 49 1 0 0 0 0 24 25 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 25 30 1 0 0 0 0 25 52 1 0 0 0 0 25 53 1 0 0 0 0 26 30 1 0 0 0 0 26 27 1 0 0 0 0 26 54 1 0 0 0 0 26 55 1 0 0 0 0 27 31 1 0 0 0 0 27 56 1 0 0 0 0 27 57 1 0 0 0 0 28 31 1 0 0 0 0 28 29 1 0 0 0 0 28 58 1 0 0 0 0 28 59 1 0 0 0 0 29 30 1 0 0 0 0 29 60 1 0 0 0 0 29 61 1 0 0 0 0 31 32 1 0 0 0 0 32 62 1 0 0 0 0 32 63 1 0 0 0 0 32 64 1 0 0 0 0 M END > (30) 28 > (30) C24H32N6O2 > (30) 436.5558 > (30) FGFR-P28 > (30) 1,6-naphthyridine 15 > (30) FGFR-1 Tyrosine Kinase > (30) 44 > (30) BINDDB > (30) <2007 > (30) P > (30) TRAIN $$$$ 1,6-naphthyridine 16 csChFnd70/04170815452D 74 77 0 0 0 0 0 0 0 0999 V2000 2.7518 18.9685 0.0127 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8871 18.8738 -0.0178 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3267 19.8341 0.0022 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3987 16.2670 -0.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7766 17.1436 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2428 16.1646 0.0114 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8081 13.5953 -0.0179 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3860 14.4453 -0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3139 14.4616 0.0010 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8814 17.1654 -0.0269 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3740 21.7579 0.0116 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4605 24.4308 1.2049 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4635 25.3594 0.0280 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4188 22.6331 1.2001 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3794 22.6946 -1.1734 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4272 24.4921 -1.1616 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4570 25.4067 -2.3164 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5685 27.2560 -2.2316 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4792 25.2853 2.3638 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4595 27.1385 2.2962 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7797 11.7916 -0.0279 N 0 0 3 0 0 0 0 0 0 0 0 0 4.4111 10.8151 -0.0488 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0177 8.8688 -0.0562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7214 7.8492 -0.0780 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0124 5.5472 1.2101 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5824 3.6116 1.0908 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4998 3.0256 0.0841 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9299 4.9612 0.2035 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3437 5.9803 -0.0851 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1685 2.5925 1.3793 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7908 0.7237 1.3722 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4616 19.7503 -0.0287 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9625 18.8520 -0.0484 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9377 17.2743 -0.0567 O 0 0 0 0 0 0 0 0 0 0 0 0 10.4908 19.7028 -0.0591 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1223 18.7263 -0.0805 C 0 0 0 0 0 0 0 0 0 0 0 0 13.6517 19.9930 -0.0889 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5405 19.6739 0.0337 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.8125 0.0273 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5869 13.7225 -0.0427 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4980 26.7606 0.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1950 21.9108 2.1170 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5726 22.0202 -2.1002 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9060 27.6585 -2.4557 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7326 27.8247 -3.2212 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1517 27.6953 -0.9530 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8928 27.5685 1.0198 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1445 27.6049 2.5296 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3263 27.6558 3.2873 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6797 11.1793 -0.0211 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1473 11.1519 -1.2089 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1690 11.1387 1.1011 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2814 8.5321 1.1039 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2598 8.5453 -1.2061 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4576 8.1858 -1.2380 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4793 8.1726 1.0719 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8452 6.3062 0.9594 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4993 5.8435 2.5048 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6225 3.2797 2.0756 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0622 3.3219 -0.1923 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0129 2.7293 -1.2105 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6671 2.2666 0.3350 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4501 5.2509 1.4867 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8898 5.2931 -0.7813 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2385 0.3590 0.1220 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9869 0.0000 1.5886 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8666 0.4256 2.4010 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4815 21.0089 -0.0222 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5107 20.9616 -0.0526 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1959 17.9058 1.0694 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1729 17.9182 -1.2405 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5779 20.8136 -1.2389 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6009 20.8012 1.0711 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8654 19.2665 -0.1049 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 3 2 0 0 0 0 1 38 1 0 0 0 0 2 10 2 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 11 1 0 0 0 0 4 10 1 0 0 0 0 4 8 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 6 39 1 0 0 0 0 7 9 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 40 1 0 0 0 0 11 15 1 0 0 0 0 11 14 2 0 0 0 0 12 14 1 0 0 0 0 12 13 2 0 0 0 0 12 19 1 0 0 0 0 13 16 1 0 0 0 0 13 41 1 0 0 0 0 14 42 1 0 0 0 0 15 16 2 0 0 0 0 15 43 1 0 0 0 0 16 17 1 0 0 0 0 17 18 1 0 0 0 0 18 44 1 0 0 0 0 18 45 1 0 0 0 0 18 46 1 0 0 0 0 19 20 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 21 22 1 0 0 0 0 21 50 1 0 0 0 0 22 23 1 0 0 0 0 22 51 1 0 0 0 0 22 52 1 0 0 0 0 23 24 1 0 0 0 0 23 53 1 0 0 0 0 23 54 1 0 0 0 0 24 29 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 57 1 0 0 0 0 25 58 1 0 0 0 0 26 30 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 27 30 1 0 0 0 0 27 28 1 0 0 0 0 27 61 1 0 0 0 0 27 62 1 0 0 0 0 28 29 1 0 0 0 0 28 63 1 0 0 0 0 28 64 1 0 0 0 0 30 31 1 0 0 0 0 31 65 1 0 0 0 0 31 66 1 0 0 0 0 31 67 1 0 0 0 0 32 33 1 0 0 0 0 32 68 1 0 0 0 0 33 34 2 0 0 0 0 33 35 1 0 0 0 0 35 36 1 0 0 0 0 35 69 1 0 0 0 0 36 37 1 0 0 0 0 36 70 1 0 0 0 0 36 71 1 0 0 0 0 37 72 1 0 0 0 0 37 73 1 0 0 0 0 37 74 1 0 0 0 0 M END > (31) 29 > (31) C27H37N7O3 > (31) 507.6344 > (31) FGFR-P29 > (31) 1,6-naphthyridine 16 > (31) FGFR-1 Tyrosine Kinase > (31) 21 > (31) BINDDB > (31) <2007 > (31) P > (31) TRAIN $$$$ 1,6-naphthyridine 17 csChFnd70/04170815452D 80 83 0 0 0 0 0 0 0 0999 V2000 2.7517 18.9683 0.0127 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8871 18.8736 -0.0178 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3267 19.8338 0.0022 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3987 16.2668 -0.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7765 17.1434 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2428 16.1644 0.0114 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8080 13.5952 -0.0179 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3860 14.4452 -0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3139 14.4615 0.0010 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8814 17.1652 -0.0269 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3739 21.7577 0.0116 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4605 24.4305 1.2049 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4635 25.3591 0.0280 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4188 22.6329 1.2001 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3793 22.6944 -1.1734 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4271 24.4918 -1.1616 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4569 25.4064 -2.3164 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5684 27.2557 -2.2315 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4792 25.2850 2.3638 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4595 27.1382 2.2961 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7796 11.7914 -0.0279 N 0 0 3 0 0 0 0 0 0 0 0 0 4.4110 10.8150 -0.0488 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0176 8.8687 -0.0562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7214 7.8491 -0.0780 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0123 5.5472 1.2101 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5823 3.6115 1.0908 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4998 3.0255 0.0841 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9298 4.9612 0.2035 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3437 5.9803 -0.0851 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1685 2.5924 1.3793 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7908 0.7237 1.3722 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4615 19.7500 -0.0287 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9624 18.8518 -0.0484 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9376 17.2741 -0.0567 O 0 0 0 0 0 0 0 0 0 0 0 0 10.4907 19.7025 -0.0591 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1932 17.5918 -1.7087 C 0 0 0 0 0 0 0 0 0 0 0 0 13.6516 19.9927 -0.0889 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1221 18.7261 -0.0805 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2254 17.5743 1.5337 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5405 19.6736 0.0337 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.8123 0.0273 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5869 13.7224 -0.0427 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4979 26.7603 0.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1950 21.9106 2.1170 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5726 22.0200 -2.1002 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9059 27.6582 -2.4556 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7326 27.8244 -3.2211 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1517 27.6950 -0.9530 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1445 27.6046 2.5296 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3262 27.6555 3.2872 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8927 27.5682 1.0198 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6797 11.1791 -0.0211 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1473 11.1517 -1.2089 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1690 11.1385 1.1011 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2813 8.5320 1.1039 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2597 8.5452 -1.2061 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4576 8.1857 -1.2380 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4793 8.1725 1.0719 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8451 6.3062 0.9594 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4993 5.8435 2.5048 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6224 3.2796 2.0756 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0621 3.3218 -0.1923 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0129 2.7292 -1.2105 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6670 2.2666 0.3350 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4500 5.2509 1.4867 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8897 5.2931 -0.7813 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2385 0.3590 0.1220 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9869 0.0000 1.5886 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8665 0.4256 2.4010 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4814 21.0086 -0.0222 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5106 20.9613 -0.0526 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1196 18.4123 -2.8588 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4070 16.8654 -1.7247 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1037 16.6894 -1.7028 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6008 20.8009 1.0711 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8653 19.2663 -0.1049 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5778 20.8133 -1.2389 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1359 16.6720 1.5396 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4394 16.8479 1.5177 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1748 18.3825 2.6937 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 3 2 0 0 0 0 1 40 1 0 0 0 0 2 10 2 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 11 1 0 0 0 0 4 10 1 0 0 0 0 4 8 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 6 41 1 0 0 0 0 7 9 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 42 1 0 0 0 0 11 15 1 0 0 0 0 11 14 2 0 0 0 0 12 14 1 0 0 0 0 12 13 2 0 0 0 0 12 19 1 0 0 0 0 13 16 1 0 0 0 0 13 43 1 0 0 0 0 14 44 1 0 0 0 0 15 16 2 0 0 0 0 15 45 1 0 0 0 0 16 17 1 0 0 0 0 17 18 1 0 0 0 0 18 46 1 0 0 0 0 18 47 1 0 0 0 0 18 48 1 0 0 0 0 19 20 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 20 51 1 0 0 0 0 21 22 1 0 0 0 0 21 52 1 0 0 0 0 22 23 1 0 0 0 0 22 53 1 0 0 0 0 22 54 1 0 0 0 0 23 24 1 0 0 0 0 23 55 1 0 0 0 0 23 56 1 0 0 0 0 24 29 1 0 0 0 0 24 57 1 0 0 0 0 24 58 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 59 1 0 0 0 0 25 60 1 0 0 0 0 26 30 1 0 0 0 0 26 61 1 0 0 0 0 26 62 1 0 0 0 0 27 30 1 0 0 0 0 27 28 1 0 0 0 0 27 63 1 0 0 0 0 27 64 1 0 0 0 0 28 29 1 0 0 0 0 28 65 1 0 0 0 0 28 66 1 0 0 0 0 30 31 1 0 0 0 0 31 67 1 0 0 0 0 31 68 1 0 0 0 0 31 69 1 0 0 0 0 32 33 1 0 0 0 0 32 70 1 0 0 0 0 33 34 2 0 0 0 0 33 35 1 0 0 0 0 35 38 1 0 0 0 0 35 71 1 0 0 0 0 36 38 1 0 0 0 0 36 72 1 0 0 0 0 36 73 1 0 0 0 0 36 74 1 0 0 0 0 37 38 1 0 0 0 0 37 75 1 0 0 0 0 37 76 1 0 0 0 0 37 77 1 0 0 0 0 38 39 1 0 0 0 0 39 78 1 0 0 0 0 39 79 1 0 0 0 0 39 80 1 0 0 0 0 M END > (32) 30 > (32) C29H41N7O3 > (32) 535.688 > (32) FGFR-P30 > (32) 1,6-naphthyridine 17 > (32) FGFR-1 Tyrosine Kinase > (32) 24 > (32) BINDDB > (32) <2007 > (32) P > (32) TRAIN $$$$ 1,6-naphthyridine 18 csChFnd70/04170815452D 77 79 0 0 0 0 0 0 0 0999 V2000 2.4239 15.7302 2.7914 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5451 16.0594 2.9081 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8630 16.7754 3.0626 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4368 13.3481 2.2352 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7055 13.9752 2.3675 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3232 12.8264 2.0712 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2364 10.5609 1.5416 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6807 11.5915 1.8099 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6335 11.1951 1.6773 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7799 14.4126 2.5100 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6390 18.6354 3.5120 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3139 21.0794 5.3402 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2206 22.1179 4.3524 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5256 19.3408 4.9242 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5472 19.6838 2.5184 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3414 21.4214 2.9413 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2763 22.4446 1.9735 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1246 24.2237 2.4830 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1781 21.7684 6.7174 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8993 23.5696 7.0723 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4624 8.8193 1.1198 N 0 0 3 0 0 0 0 0 0 0 0 0 5.2169 8.0975 0.9647 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1009 6.1696 0.4934 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9334 5.4157 0.3313 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9822 17.1152 3.1812 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5963 16.4512 3.0379 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7940 14.9278 2.6695 O 0 0 0 0 0 0 0 0 0 0 0 0 9.9915 17.4759 3.3029 N 0 0 3 0 0 0 0 0 0 0 0 0 12.0113 16.0484 1.3077 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0836 18.1798 3.5091 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7460 16.7544 3.1472 C 0 0 0 0 0 0 0 0 0 0 0 0 11.9756 15.2808 4.4619 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8221 3.5646 -0.1211 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5376 2.8704 -0.5886 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0236 3.4803 -2.4174 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0412 2.5586 1.3007 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4948 0.7705 0.6251 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1240 16.2459 2.9075 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 13.2838 2.1675 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9728 11.0560 1.6952 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0575 23.4728 4.6797 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3767 18.5329 5.6940 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8627 19.1424 1.4195 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2378 24.8924 1.6044 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6222 24.2949 3.8052 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3983 24.8407 2.4281 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6640 23.9523 8.2013 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2956 24.3385 5.9509 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5254 23.7918 7.3353 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4583 8.0819 0.9282 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9241 8.7895 -0.0487 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8976 8.2418 2.1983 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3937 5.4775 1.5067 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4202 6.0252 -0.7403 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6407 6.1076 -0.6821 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6141 5.5600 1.5650 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8246 18.3306 3.4750 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8338 18.6914 3.5968 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8477 17.0980 0.3710 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3167 15.5113 1.1918 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0583 15.0327 1.0499 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8945 18.6828 4.8196 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3889 17.6428 3.3934 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9200 19.2295 2.5725 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0227 14.2652 4.2041 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2811 14.7439 4.3460 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7866 15.7838 5.7725 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5036 3.3361 0.3367 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4985 1.4549 -0.5578 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2277 4.8817 -2.4090 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2132 2.8323 -2.8306 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9757 3.1613 -3.3153 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9877 2.4006 2.3426 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9047 3.2439 1.7952 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9762 0.0000 1.6944 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4997 0.9260 -0.3707 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6190 0.1116 0.0703 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 3 2 0 0 0 0 1 38 1 0 0 0 0 2 10 2 0 0 0 0 2 3 1 0 0 0 0 2 25 1 0 0 0 0 3 11 1 0 0 0 0 4 10 1 0 0 0 0 4 8 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 6 39 1 0 0 0 0 7 9 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 40 1 0 0 0 0 11 15 1 0 0 0 0 11 14 2 0 0 0 0 12 14 1 0 0 0 0 12 13 2 0 0 0 0 12 19 1 0 0 0 0 13 16 1 0 0 0 0 13 41 1 0 0 0 0 14 42 1 0 0 0 0 15 16 2 0 0 0 0 15 43 1 0 0 0 0 16 17 1 0 0 0 0 17 18 1 0 0 0 0 18 44 1 0 0 0 0 18 45 1 0 0 0 0 18 46 1 0 0 0 0 19 20 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 21 22 1 0 0 0 0 21 50 1 0 0 0 0 22 23 1 0 0 0 0 22 51 1 0 0 0 0 22 52 1 0 0 0 0 23 24 1 0 0 0 0 23 53 1 0 0 0 0 23 54 1 0 0 0 0 24 33 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 25 26 1 0 0 0 0 25 57 1 0 0 0 0 26 27 2 0 0 0 0 26 28 1 0 0 0 0 28 31 1 0 0 0 0 28 58 1 0 0 0 0 29 31 1 0 0 0 0 29 59 1 0 0 0 0 29 60 1 0 0 0 0 29 61 1 0 0 0 0 30 31 1 0 0 0 0 30 62 1 0 0 0 0 30 63 1 0 0 0 0 30 64 1 0 0 0 0 31 32 1 0 0 0 0 32 65 1 0 0 0 0 32 66 1 0 0 0 0 32 67 1 0 0 0 0 33 36 1 0 0 0 0 33 34 1 0 0 0 0 34 35 1 0 0 0 0 34 68 1 0 0 0 0 34 69 1 0 0 0 0 35 70 1 0 0 0 0 35 71 1 0 0 0 0 35 72 1 0 0 0 0 36 37 1 0 0 0 0 36 73 1 0 0 0 0 36 74 1 0 0 0 0 37 75 1 0 0 0 0 37 76 1 0 0 0 0 37 77 1 0 0 0 0 M END > (33) 31 > (33) C28H40N6O3 > (33) 508.6624 > (33) FGFR-P31 > (33) 1,6-naphthyridine 18 > (33) FGFR-1 Tyrosine Kinase > (33) 60 > (33) BINDDB > (33) <2007 > (33) P > (33) TRAIN $$$$ 1,6-naphthyridin 19 csChFnd70/04170815452D 79 82 0 0 0 0 0 0 0 0999 V2000 1.2227 15.6157 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7133 13.0065 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3127 13.8109 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7815 16.5501 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3766 15.6293 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8075 18.3728 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9353 18.1908 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4041 19.1932 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 13.9133 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8820 16.4851 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5050 21.1127 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6346 23.8684 -1.1645 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5378 22.0750 -1.1759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5617 21.9586 1.2041 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6525 23.7524 1.2085 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6930 24.7062 0.0237 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6915 24.8080 -2.3185 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8534 26.6514 -2.2340 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6822 24.5783 2.3752 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7140 26.4292 2.3068 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5318 19.0219 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0052 18.0832 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9364 16.5087 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5549 18.8900 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1566 17.8696 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1954 16.7340 -1.7107 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7190 19.0915 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2283 16.7176 1.5280 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6343 11.2063 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2359 10.1858 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7884 8.2533 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4609 7.1874 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0134 5.2551 -0.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9515 1.3587 0.0898 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2565 2.3853 0.1990 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8673 4.8927 1.1770 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5463 3.8410 1.0581 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6194 4.2317 -0.1029 N 0 0 0 0 0 0 0 0 0 0 0 0 9.1624 2.0454 1.3145 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.2975 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4914 13.0554 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6179 19.1109 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7138 21.4236 -2.1017 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3086 21.2168 2.1271 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7665 26.1044 0.0297 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4488 27.1017 -0.9572 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2001 27.0168 -2.4574 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0349 27.2422 -3.2229 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1702 26.8459 1.0358 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4117 26.9312 2.5275 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5844 26.9226 3.3046 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5866 20.2781 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6098 20.1463 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1445 17.5547 -2.8599 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3871 15.9748 -1.7266 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0825 15.8635 -1.7038 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6914 19.9005 1.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9106 18.3324 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6679 19.9123 -1.2437 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1153 15.8470 1.5349 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4199 15.9584 1.5121 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2006 17.5266 2.6862 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5190 10.6258 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9802 10.5008 -1.2056 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0019 10.4877 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0440 7.9382 1.1055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0225 7.9513 -1.2019 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2053 7.5026 -1.2341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2270 7.4895 1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2691 4.9399 1.0770 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2475 4.9532 -1.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7003 0.0000 0.3859 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4860 1.4674 -1.2137 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3558 1.9147 -0.7829 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6865 2.2199 1.4814 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3229 4.7675 2.4750 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1423 6.2526 0.9090 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1268 4.0220 -0.2173 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4482 4.2777 2.0544 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 40 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 41 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 42 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 43 1 0 0 0 0 14 15 1 0 0 0 0 14 44 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 45 1 0 0 0 0 17 18 1 0 0 0 0 18 46 1 0 0 0 0 18 47 1 0 0 0 0 18 48 1 0 0 0 0 19 20 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 20 51 1 0 0 0 0 21 22 1 0 0 0 0 21 52 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 24 25 1 0 0 0 0 24 53 1 0 0 0 0 25 26 1 0 0 0 0 25 27 1 0 0 0 0 25 28 1 0 0 0 0 26 54 1 0 0 0 0 26 55 1 0 0 0 0 26 56 1 0 0 0 0 27 57 1 0 0 0 0 27 58 1 0 0 0 0 27 59 1 0 0 0 0 28 60 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 29 30 1 0 0 0 0 29 63 1 0 0 0 0 30 31 1 0 0 0 0 30 64 1 0 0 0 0 30 65 1 0 0 0 0 31 32 1 0 0 0 0 31 66 1 0 0 0 0 31 67 1 0 0 0 0 32 33 1 0 0 0 0 32 68 1 0 0 0 0 32 69 1 0 0 0 0 33 38 1 0 0 0 0 33 70 1 0 0 0 0 33 71 1 0 0 0 0 34 39 1 0 0 0 0 34 35 1 0 0 0 0 34 72 1 0 0 0 0 34 73 1 0 0 0 0 35 38 1 0 0 0 0 35 74 1 0 0 0 0 35 75 1 0 0 0 0 36 38 1 0 0 0 0 36 37 1 0 0 0 0 36 76 1 0 0 0 0 36 77 1 0 0 0 0 37 39 1 0 0 0 0 37 78 1 0 0 0 0 37 79 1 0 0 0 0 M END > (34) 32 > (34) C29H40N6O4 > (34) 536.6728 > (34) FGFR-P32 > (34) 1,6-naphthyridine 19 > (34) FGFR-1 Tyrosine Kinase > (34) 30 > (34) BINDDB > (34) <2007 > (34) P > (34) TRAIN $$$$ 1,6-naphthyridin 20 csChFnd70/04170815452D 83 86 0 0 0 0 0 0 0 0999 V2000 1.2227 15.9686 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 13.3593 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3129 14.1638 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7816 16.9031 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3768 15.9823 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8076 18.7259 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9356 18.5438 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4043 19.5462 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2459 14.2662 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8823 16.8380 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5052 21.4658 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6348 24.2216 -1.1646 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5380 22.4281 -1.1759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5620 22.3117 1.2041 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6528 24.1056 1.2085 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6932 25.0596 0.0237 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6916 25.1613 -2.3186 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8535 27.0048 -2.2341 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6825 24.9316 2.3753 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7143 26.7826 2.3069 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5321 19.3750 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0056 18.4363 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9368 16.8616 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5554 19.2430 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1571 18.2225 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1959 17.0869 -1.7108 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7195 19.4446 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2288 17.0706 1.5281 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6344 11.5589 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2361 10.5384 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7886 8.6059 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4611 7.5400 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0136 5.6076 -0.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9458 1.7055 0.0649 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2569 2.7383 0.1989 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8691 5.2480 1.1731 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5579 4.2153 1.0392 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6197 4.5841 -0.1029 N 0 0 0 0 0 0 0 0 0 0 0 0 9.1951 2.3695 1.3409 N 0 0 0 0 0 0 0 0 0 0 0 0 10.8012 1.3460 1.3201 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.6504 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4916 13.4081 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6180 19.4639 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7139 21.7767 -2.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3089 21.5699 2.1272 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7667 26.4577 0.0297 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0350 27.5955 -3.2231 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4489 27.4551 -0.9572 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2003 27.3702 -2.4575 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1705 27.1993 1.0358 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4119 27.2846 2.5276 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5847 27.2760 3.3048 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5869 20.6312 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6103 20.4994 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1450 17.9076 -2.8600 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3876 16.3277 -1.7267 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0829 16.2164 -1.7039 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6919 20.2536 1.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9112 18.6854 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6684 20.2653 -1.2438 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1157 16.1999 1.5350 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4204 16.3113 1.5122 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2011 17.8795 2.6863 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5191 10.9785 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9804 10.8535 -1.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0021 10.8403 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0441 8.2908 1.1055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0226 8.3039 -1.2019 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2056 7.8552 -1.2341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2273 7.8421 1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2693 5.2924 1.0770 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2477 5.3056 -1.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6860 0.3411 0.3254 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4814 1.8441 -1.2354 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3416 2.2729 -0.7717 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7031 2.5713 1.4882 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3334 5.1096 2.4734 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1289 6.6124 0.9125 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1118 4.3823 -0.2501 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4733 4.6806 2.0099 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3861 1.4137 0.0355 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7028 1.8651 2.2763 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5060 0.0000 1.6330 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 41 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 42 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 43 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 44 1 0 0 0 0 14 15 1 0 0 0 0 14 45 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 46 1 0 0 0 0 17 18 1 0 0 0 0 18 47 1 0 0 0 0 18 48 1 0 0 0 0 18 49 1 0 0 0 0 19 20 1 0 0 0 0 20 50 1 0 0 0 0 20 51 1 0 0 0 0 20 52 1 0 0 0 0 21 22 1 0 0 0 0 21 53 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 24 25 1 0 0 0 0 24 54 1 0 0 0 0 25 26 1 0 0 0 0 25 27 1 0 0 0 0 25 28 1 0 0 0 0 26 55 1 0 0 0 0 26 56 1 0 0 0 0 26 57 1 0 0 0 0 27 58 1 0 0 0 0 27 59 1 0 0 0 0 27 60 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 28 63 1 0 0 0 0 29 30 1 0 0 0 0 29 64 1 0 0 0 0 30 31 1 0 0 0 0 30 65 1 0 0 0 0 30 66 1 0 0 0 0 31 32 1 0 0 0 0 31 67 1 0 0 0 0 31 68 1 0 0 0 0 32 33 1 0 0 0 0 32 69 1 0 0 0 0 32 70 1 0 0 0 0 33 38 1 0 0 0 0 33 71 1 0 0 0 0 33 72 1 0 0 0 0 34 39 1 0 0 0 0 34 35 1 0 0 0 0 34 73 1 0 0 0 0 34 74 1 0 0 0 0 35 38 1 0 0 0 0 35 75 1 0 0 0 0 35 76 1 0 0 0 0 36 38 1 0 0 0 0 36 37 1 0 0 0 0 36 77 1 0 0 0 0 36 78 1 0 0 0 0 37 39 1 0 0 0 0 37 79 1 0 0 0 0 37 80 1 0 0 0 0 39 40 1 0 0 0 0 40 81 1 0 0 0 0 40 82 1 0 0 0 0 40 83 1 0 0 0 0 M END > (35) 33 > (35) C30H43N7O3 > (35) 549.7148 > (35) FGFR-P33 > (35) 1,6-naphthyridine 20 > (35) FGFR-1 Tyrosine Kinase > (35) 24 > (35) BINDDB > (35) <2007 > (35) P > (35) TRAIN $$$$ 1,6-naphthyridin 21 csChFnd70/04170815452D 64 66 0 0 0 0 0 0 0 0999 V2000 1.0238 15.8611 -0.3265 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8033 12.9003 -0.2857 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5893 13.2711 -0.2692 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8036 16.3700 -0.3115 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1310 15.0438 -0.2819 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3092 18.1578 -0.3255 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3402 17.1554 -0.2803 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0955 18.5455 -0.3096 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5980 14.1793 -0.3133 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8383 15.4895 -0.2676 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6996 20.4084 -0.3240 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5061 22.7254 0.8864 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9441 20.9838 0.9039 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0296 21.5855 -1.5702 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5973 23.3252 -1.5803 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8317 23.8954 -0.3520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7192 23.2879 2.0837 O 0 0 0 0 0 0 0 0 0 0 0 0 9.2393 25.0998 1.9900 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9447 24.4741 -2.7952 O 0 0 0 0 0 0 0 0 0 0 0 0 5.5878 26.2473 -2.7297 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1239 17.5519 -0.2646 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2516 11.1493 -0.2738 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5589 9.7231 -0.2434 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6096 7.9391 -0.2359 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9751 6.4496 -0.2042 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0258 4.6656 -0.1967 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3368 3.2355 -0.1663 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3293 3.2373 1.5009 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9956 2.1129 1.2943 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4954 1.5143 -0.4727 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0438 1.3247 -2.4333 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.8542 -0.3430 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5505 12.2172 -0.2463 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3323 19.1970 -0.3483 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4695 20.0737 1.8683 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0695 21.1422 -2.5274 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2721 25.2521 -0.3628 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8174 25.3671 0.6989 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0865 25.9405 2.1830 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2106 25.3740 3.0167 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0145 26.2480 -2.9239 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9619 27.0236 -3.7682 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2780 26.8232 -1.4471 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9899 16.6080 -0.2445 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5084 18.7740 -0.2737 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0008 10.8717 -0.2857 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3973 9.8157 -1.4103 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3697 9.8404 0.9406 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7714 7.8465 0.9308 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7990 7.8218 -1.4198 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8135 6.5423 -1.3710 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7857 6.5669 0.9798 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1875 4.5730 0.9700 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2152 4.5483 -1.3807 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6999 4.5874 1.8373 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5078 2.6900 2.5490 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7219 2.0985 2.5373 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6257 0.7678 0.9389 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8263 2.6716 0.2595 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3987 0.4626 -0.0844 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2894 1.4237 0.3084 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5386 0.0000 -2.6835 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0428 2.2956 -2.7913 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2283 1.5437 -3.2219 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 32 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 22 1 0 0 0 0 3 5 2 0 0 0 0 3 33 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 34 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 35 1 0 0 0 0 14 15 1 0 0 0 0 14 36 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 37 1 0 0 0 0 17 18 1 0 0 0 0 18 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 19 20 1 0 0 0 0 20 41 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 44 1 0 0 0 0 21 45 1 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 25 26 1 0 0 0 0 25 51 1 0 0 0 0 25 52 1 0 0 0 0 26 27 1 0 0 0 0 26 53 1 0 0 0 0 26 54 1 0 0 0 0 27 28 1 0 0 0 0 27 30 1 0 0 0 0 28 29 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 29 57 1 0 0 0 0 29 58 1 0 0 0 0 29 59 1 0 0 0 0 30 31 1 0 0 0 0 30 60 1 0 0 0 0 30 61 1 0 0 0 0 31 62 1 0 0 0 0 31 63 1 0 0 0 0 31 64 1 0 0 0 0 M END > (36) 34 > (36) C24H33N5O2 > (36) 423.557 > (36) FGFR-P34 > (36) 1,6-naphthyridine 21 > (36) FGFR-1 Tyrosine Kinase > (36) 87 > (36) BINDDB > (36) <2007 > (36) P > (36) TRAIN $$$$ 1,6-naphthyridin 22 csChFnd70/04170815452D 74 76 0 0 0 0 0 0 0 0999 V2000 1.0110 15.6610 -0.3232 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7805 12.7379 -0.2826 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5440 13.1035 -0.2660 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7686 16.1635 -0.3083 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0792 14.8539 -0.2788 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2682 17.9280 -0.3223 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2601 16.9375 -0.2773 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0330 18.3098 -0.3065 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5905 14.0007 -0.3101 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7645 15.2938 -0.2653 N 0 0 0 0 0 0 0 0 0 0 0 0 5.6306 20.1488 -0.3207 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5255 23.0306 -1.5563 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9644 21.3132 -1.5465 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8539 20.7182 0.8963 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4095 22.4375 0.8794 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7492 23.5914 -0.3476 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8769 24.1669 -2.7517 O 0 0 0 0 0 0 0 0 0 0 0 0 5.5128 25.9175 -2.6871 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6021 22.9941 2.0662 O 0 0 0 0 0 0 0 0 0 0 0 0 9.1166 24.7829 1.9737 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2356 11.0090 -0.2702 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5262 9.6007 -0.2400 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5886 7.8393 -0.2319 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9366 6.3686 -0.2003 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9990 4.6073 -0.1921 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2933 3.1952 -0.1618 N 0 0 0 0 0 0 0 0 0 0 0 0 4.2733 3.1974 1.4841 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9184 2.0868 1.2802 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4621 1.4957 -0.4638 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0160 1.3081 -2.3993 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0277 17.3297 -0.2623 N 0 0 3 0 0 0 0 0 0 0 0 0 9.2152 16.0344 -0.2358 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7388 14.5223 -0.2250 O 0 0 0 0 0 0 0 0 0 0 0 0 10.9310 16.4152 -0.2213 N 0 0 3 0 0 0 0 0 0 0 0 0 12.2220 15.0072 -0.1925 C 0 0 0 0 0 0 0 0 0 0 0 0 14.0580 15.7881 -0.1809 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.6416 -0.3397 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4927 12.0627 -0.2434 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3041 18.9544 -0.3449 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0121 20.8773 -2.4881 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3681 19.8207 1.8521 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1845 24.9309 -0.3580 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9205 25.9178 -2.8844 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8910 26.6854 -3.7089 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2120 26.4843 -1.4188 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0711 25.0546 2.9914 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6932 25.0448 0.7011 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9778 25.6135 2.1580 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0007 10.7351 -0.2817 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3538 9.6916 -1.3922 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3268 9.7168 0.9288 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7611 7.7484 0.9203 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7881 7.7234 -1.4008 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7642 6.4595 -1.3524 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7372 6.4847 0.9686 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1715 4.5163 0.9600 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1985 4.4912 -1.3609 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6394 4.5303 1.8158 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4624 2.6572 2.5193 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5530 0.7586 0.9299 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7385 2.6379 0.2584 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6358 2.0728 2.5074 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3540 0.4574 -0.0801 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2717 1.4068 0.3078 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0278 2.2665 -2.7530 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1854 1.5236 -3.1782 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5170 0.0000 -2.6459 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4078 18.5363 -0.2709 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3111 17.6217 -0.2299 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0356 14.2172 0.9746 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0607 14.1928 -1.3465 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0185 14.7405 -0.1595 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2442 16.5780 -1.3481 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2192 16.6024 0.9730 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 37 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 5 2 0 0 0 0 3 38 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 39 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 31 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 40 1 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 42 1 0 0 0 0 17 18 1 0 0 0 0 18 43 1 0 0 0 0 18 44 1 0 0 0 0 18 45 1 0 0 0 0 19 20 1 0 0 0 0 20 46 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 21 22 1 0 0 0 0 21 49 1 0 0 0 0 22 23 1 0 0 0 0 22 50 1 0 0 0 0 22 51 1 0 0 0 0 23 24 1 0 0 0 0 23 52 1 0 0 0 0 23 53 1 0 0 0 0 24 25 1 0 0 0 0 24 54 1 0 0 0 0 24 55 1 0 0 0 0 25 26 1 0 0 0 0 25 56 1 0 0 0 0 25 57 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 27 58 1 0 0 0 0 27 59 1 0 0 0 0 28 60 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 29 30 1 0 0 0 0 29 63 1 0 0 0 0 29 64 1 0 0 0 0 30 65 1 0 0 0 0 30 66 1 0 0 0 0 30 67 1 0 0 0 0 31 32 1 0 0 0 0 31 68 1 0 0 0 0 32 33 2 0 0 0 0 32 34 1 0 0 0 0 34 35 1 0 0 0 0 34 69 1 0 0 0 0 35 36 1 0 0 0 0 35 70 1 0 0 0 0 35 71 1 0 0 0 0 36 72 1 0 0 0 0 36 73 1 0 0 0 0 36 74 1 0 0 0 0 M END > (37) 35 > (37) C27H38N6O3 > (37) 494.6356 > (37) FGFR-P35 > (37) 1,6-naphthyridine 22 > (37) FGFR-1 Tyrosine Kinase > (37) 24 > (37) BINDDB > (37) <2007 > (37) P > (37) TRAIN $$$$ 1,6-naphthyridin 23 csChFnd70/04170815452D 80 82 0 0 0 0 0 0 0 0999 V2000 1.0153 15.6708 0.6533 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8100 12.7700 0.4828 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5618 13.1548 0.4144 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7600 16.1919 0.5916 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0774 14.9038 0.4685 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2401 17.9543 0.6473 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2278 17.0039 0.4573 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9930 18.3555 0.5791 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6131 14.0130 0.5978 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7506 15.3617 0.4061 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5697 20.1934 0.6329 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3643 23.1281 -0.4252 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8224 21.4118 -0.4789 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8548 20.7073 1.8007 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3907 22.4257 1.8476 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6493 23.6339 0.7337 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6367 24.3171 -1.5096 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2571 26.0631 -1.3847 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6436 22.9281 2.9865 O 0 0 0 0 0 0 0 0 0 0 0 0 9.1334 24.7193 2.9648 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2844 11.0424 0.4300 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5829 9.6557 0.3034 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6668 7.8913 0.2682 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0230 6.4430 0.1361 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1069 4.6785 0.1008 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4090 3.2881 -0.0260 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6098 1.5756 0.2455 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2390 1.3169 2.1817 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3240 3.3583 -1.7001 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9810 2.2641 -1.5961 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9833 17.4155 0.3887 N 0 0 3 0 0 0 0 0 0 0 0 0 9.1779 16.1399 0.2710 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7184 14.6290 0.2248 O 0 0 0 0 0 0 0 0 0 0 0 0 10.8819 16.5395 0.2043 N 0 0 3 0 0 0 0 0 0 0 0 0 11.8680 14.1035 -1.5833 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1806 15.1531 0.0763 C 0 0 0 0 0 0 0 0 0 0 0 0 14.0004 15.9525 0.0221 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0294 13.9556 1.6563 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.6347 0.7527 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5164 12.1300 0.3216 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2703 18.9649 0.7402 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8224 21.0187 -1.3818 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4322 19.7675 2.6685 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0694 24.9726 0.7729 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5700 26.8765 -2.3190 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0293 26.5525 -0.0751 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6454 26.0919 -1.6647 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0044 25.5213 3.2628 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1418 24.9449 3.9338 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6277 25.0581 1.6813 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0578 10.7550 0.4771 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3357 9.8208 -0.8850 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4488 9.7160 1.4230 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9141 7.7263 1.4568 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8011 7.8310 -0.8512 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7757 6.6080 -1.0524 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8888 6.5033 1.2556 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3542 4.5135 1.2894 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2411 4.6182 -1.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3965 1.5001 -0.4818 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4943 0.5651 -0.2051 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7646 0.0000 2.3998 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4302 1.5182 2.9217 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2582 2.2480 2.6033 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4837 2.8468 -2.7194 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6628 4.7014 -1.9970 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6501 2.3008 -2.8442 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8299 2.7872 -0.5897 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6436 0.9252 -1.2803 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3499 18.6210 0.4255 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2485 17.7452 0.2411 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9757 14.9566 -2.7089 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8342 13.0720 -1.6785 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5715 13.5340 -1.5447 H 0 0 0 0 0 0 0 0 0 0 0 0 14.2230 16.7003 1.2044 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9665 14.9209 -0.0732 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1080 16.8057 -1.1035 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7329 13.3861 1.6948 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9956 12.9240 1.5610 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2520 14.7034 2.8385 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 39 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 5 2 0 0 0 0 3 40 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 41 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 31 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 42 1 0 0 0 0 14 15 1 0 0 0 0 14 43 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 44 1 0 0 0 0 17 18 1 0 0 0 0 18 45 1 0 0 0 0 18 46 1 0 0 0 0 18 47 1 0 0 0 0 19 20 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 21 22 1 0 0 0 0 21 51 1 0 0 0 0 22 23 1 0 0 0 0 22 52 1 0 0 0 0 22 53 1 0 0 0 0 23 24 1 0 0 0 0 23 54 1 0 0 0 0 23 55 1 0 0 0 0 24 25 1 0 0 0 0 24 56 1 0 0 0 0 24 57 1 0 0 0 0 25 26 1 0 0 0 0 25 58 1 0 0 0 0 25 59 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 27 28 1 0 0 0 0 27 60 1 0 0 0 0 27 61 1 0 0 0 0 28 62 1 0 0 0 0 28 63 1 0 0 0 0 28 64 1 0 0 0 0 29 30 1 0 0 0 0 29 65 1 0 0 0 0 29 66 1 0 0 0 0 30 67 1 0 0 0 0 30 68 1 0 0 0 0 30 69 1 0 0 0 0 31 32 1 0 0 0 0 31 70 1 0 0 0 0 32 33 2 0 0 0 0 32 34 1 0 0 0 0 34 36 1 0 0 0 0 34 71 1 0 0 0 0 35 36 1 0 0 0 0 35 72 1 0 0 0 0 35 73 1 0 0 0 0 35 74 1 0 0 0 0 36 37 1 0 0 0 0 36 38 1 0 0 0 0 37 75 1 0 0 0 0 37 76 1 0 0 0 0 37 77 1 0 0 0 0 38 78 1 0 0 0 0 38 79 1 0 0 0 0 38 80 1 0 0 0 0 M END > (38) 36 > (38) C29H42N6O3 > (38) 522.6892 > (38) FGFR-P36 > (38) 1,6-naphthyridine 23 > (38) FGFR-1 Tyrosine Kinase > (38) 25 > (38) BINDDB > (38) <2007 > (38) P > (38) TRAIN $$$$ 1,6-naphthyridin 24 csChFnd70/04170815452D 82 85 0 0 0 0 0 0 0 0999 V2000 1.2265 17.1084 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7216 14.4913 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3258 15.2982 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7900 18.0457 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3899 17.1220 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8161 19.8739 0.0111 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9533 19.6914 -0.0204 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4175 20.6968 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2496 15.4008 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8999 17.9804 -0.0291 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5187 22.6221 0.0077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6462 25.3862 -1.1689 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5485 23.5873 -1.1798 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5786 23.4705 1.2075 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6702 25.2698 1.2114 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7084 26.2265 0.0226 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7008 26.3284 -2.3269 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8637 28.1775 -2.2425 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7032 26.0984 2.3816 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7356 27.9549 2.3124 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6423 12.6856 -0.0252 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2487 11.6619 -0.0460 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7999 9.7237 -0.0521 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4775 8.6546 -0.0739 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0288 6.7164 -0.0800 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5547 20.5250 -0.0325 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0326 19.5834 -0.0529 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9635 18.0041 -0.0609 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5869 20.3926 -0.0648 N 0 0 3 0 0 0 0 0 0 0 0 0 12.2320 18.2307 -1.7181 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1935 19.3691 -0.0870 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7607 20.5948 -0.0966 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2658 18.2130 1.5305 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7063 5.6472 -0.1017 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9335 3.3897 1.1949 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4690 1.4568 1.0914 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3425 0.7945 0.0885 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8361 2.7210 0.1818 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2754 3.7863 -0.1075 N 0 0 0 0 0 0 0 0 0 0 0 0 6.0082 0.4421 1.3352 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.7922 0.0333 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5081 14.5403 -0.0420 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6228 20.6142 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7216 22.9339 -2.1080 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3274 22.7265 2.1337 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7821 27.6289 0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2145 28.5434 -2.4664 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0431 28.7698 -3.2349 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4578 28.6296 -0.9621 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1935 28.3722 1.0375 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4294 28.4588 2.5333 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6086 28.4498 3.3131 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5236 12.1034 -0.0177 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9952 11.9777 -1.2087 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0172 11.9652 1.1057 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0535 9.4079 1.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0316 9.4203 -1.2038 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2241 8.9703 -1.2366 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2460 8.9579 1.0778 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2823 6.4006 1.0828 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2603 6.4131 -1.2317 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6097 21.7849 -0.0263 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6421 21.6527 -0.0585 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1805 19.0543 -2.8704 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4273 17.4692 -1.7346 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1155 17.3575 -1.7112 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7332 21.4057 1.0654 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9558 19.8334 -0.1131 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7092 21.4185 -1.2490 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1493 17.3398 1.5374 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4611 17.4515 1.5140 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2384 19.0242 2.6926 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4529 5.9631 -1.2644 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4748 5.9506 1.0500 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7780 4.1688 0.9360 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4270 3.6893 2.4891 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5287 1.1412 2.1039 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9105 1.1716 -0.1798 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8676 0.4901 -1.2118 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4804 0.0000 0.3757 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3760 3.0097 1.4601 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7994 3.0116 -0.8165 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 41 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 5 2 0 0 0 0 3 42 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 43 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 26 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 44 1 0 0 0 0 14 15 1 0 0 0 0 14 45 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 46 1 0 0 0 0 17 18 1 0 0 0 0 18 47 1 0 0 0 0 18 48 1 0 0 0 0 18 49 1 0 0 0 0 19 20 1 0 0 0 0 20 50 1 0 0 0 0 20 51 1 0 0 0 0 20 52 1 0 0 0 0 21 22 1 0 0 0 0 21 53 1 0 0 0 0 22 23 1 0 0 0 0 22 54 1 0 0 0 0 22 55 1 0 0 0 0 23 24 1 0 0 0 0 23 56 1 0 0 0 0 23 57 1 0 0 0 0 24 25 1 0 0 0 0 24 58 1 0 0 0 0 24 59 1 0 0 0 0 25 34 1 0 0 0 0 25 60 1 0 0 0 0 25 61 1 0 0 0 0 26 27 1 0 0 0 0 26 62 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 29 31 1 0 0 0 0 29 63 1 0 0 0 0 30 31 1 0 0 0 0 30 64 1 0 0 0 0 30 65 1 0 0 0 0 30 66 1 0 0 0 0 31 32 1 0 0 0 0 31 33 1 0 0 0 0 32 67 1 0 0 0 0 32 68 1 0 0 0 0 32 69 1 0 0 0 0 33 70 1 0 0 0 0 33 71 1 0 0 0 0 33 72 1 0 0 0 0 34 39 1 0 0 0 0 34 73 1 0 0 0 0 34 74 1 0 0 0 0 35 39 1 0 0 0 0 35 36 1 0 0 0 0 35 75 1 0 0 0 0 35 76 1 0 0 0 0 36 40 1 0 0 0 0 36 77 1 0 0 0 0 36 78 1 0 0 0 0 37 40 1 0 0 0 0 37 38 1 0 0 0 0 37 79 1 0 0 0 0 37 80 1 0 0 0 0 38 39 1 0 0 0 0 38 81 1 0 0 0 0 38 82 1 0 0 0 0 M END > (39) 37 > (39) C30H42N6O4 > (39) 550.6996 > (39) FGFR-P37 > (39) 1,6-naphthyridine 24 > (39) FGFR-1 Tyrosine Kinase > (39) 33 > (39) BINDDB > (39) <2007 > (39) P > (39) TRAIN $$$$ Anilinoquinazoline deriv. 10 csChFnd70/04170815452D 40 42 0 0 0 0 0 0 0 0999 V2000 3.2824 5.3679 -0.4999 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3238 3.9573 -0.7398 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5862 3.2139 -0.6301 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8119 3.8904 -0.2787 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5136 6.0804 -0.1411 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7937 5.3361 -0.0287 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5281 7.5406 0.1186 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9092 7.3988 0.5461 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7385 8.1370 0.4536 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9591 6.0444 0.3164 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3743 9.7836 0.1439 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2288 11.9825 0.5796 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6350 10.4800 -0.0558 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6898 11.9269 0.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3153 8.3235 0.0254 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4221 7.8612 -0.1222 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6007 1.8111 -0.8728 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9192 1.1126 -0.7447 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1272 3.2662 -1.0882 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8744 4.0813 -1.1830 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4854 12.6763 0.3807 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1702 10.5392 0.4678 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9424 9.8629 0.6680 F 0 0 0 0 0 0 0 0 0 0 0 0 3.5451 14.2498 0.5030 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9240 12.6114 -0.1316 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3052 5.9318 -0.5913 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7799 3.3098 -0.1961 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8665 7.9360 0.8217 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2936 12.5682 0.8313 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5723 9.8956 -0.3028 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3184 1.2446 0.3174 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7836 0.0000 -0.9650 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6612 1.5605 -1.4888 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.4038 -1.4679 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6624 4.5723 -0.1735 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0053 4.8894 -1.9795 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7755 14.5392 1.5837 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3645 14.6541 -0.1826 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5384 14.6940 0.1962 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0937 12.8905 -1.0909 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 26 1 0 0 0 0 2 3 2 0 0 0 0 2 19 1 0 0 0 0 3 4 1 0 0 0 0 3 17 1 0 0 0 0 4 6 2 0 0 0 0 4 27 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 7 9 2 0 0 0 0 7 15 1 0 0 0 0 8 10 2 0 0 0 0 8 9 1 0 0 0 0 8 28 1 0 0 0 0 11 15 1 0 0 0 0 11 22 1 0 0 0 0 11 13 2 0 0 0 0 12 22 2 0 0 0 0 12 21 1 0 0 0 0 12 29 1 0 0 0 0 13 14 1 0 0 0 0 13 30 1 0 0 0 0 14 21 2 0 0 0 0 14 25 1 0 0 0 0 15 16 1 0 0 0 0 17 18 1 0 0 0 0 18 31 1 0 0 0 0 18 32 1 0 0 0 0 18 33 1 0 0 0 0 19 20 1 0 0 0 0 20 34 1 0 0 0 0 20 35 1 0 0 0 0 20 36 1 0 0 0 0 21 24 1 0 0 0 0 22 23 1 0 0 0 0 24 37 1 0 0 0 0 24 38 1 0 0 0 0 24 39 1 0 0 0 0 25 40 1 0 0 0 0 M END > (383) 382 > (383) C17H16FN3O3 > (383) 329.3301 > (383) FGFR-P382 > (383) Anilinoquinazoline deriv. 10 > (383) FGFR-1 Tyrosine Kinase > (383) 2500 > (383) BINDDB > (383) <2007 > (383) P > (383) TRAIN $$$$ Anilinoquinazoline deriv. 12 csChFnd70/04170815452D 44 46 0 0 0 0 0 0 0 0999 V2000 3.7988 9.3756 0.0424 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8088 7.7659 0.0537 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2301 6.9312 0.1624 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6472 7.7167 0.2602 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2232 10.2020 0.1399 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6647 9.3664 0.2501 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2785 11.8687 0.1334 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9929 11.7328 0.3308 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6759 12.5626 0.2303 N 0 0 0 0 0 0 0 0 0 0 0 0 8.0137 10.1872 0.3420 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9809 14.3895 0.1616 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1561 16.7146 1.2646 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9335 15.3233 -0.6818 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0001 16.9446 -0.5509 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9145 12.7491 0.0285 N 0 0 3 0 0 0 0 0 0 0 0 0 2.9102 12.2292 -0.1374 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2097 5.3306 0.1720 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4246 6.9642 -0.0410 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0161 7.8810 -0.1488 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1070 17.6417 0.4187 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0977 15.0882 1.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6962 4.5477 0.2852 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4378 2.7634 0.2788 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7990 2.2939 -1.2069 O 0 0 0 0 0 0 0 0 0 0 0 0 5.5117 0.6399 -1.3371 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2480 17.4023 2.2131 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6976 10.0075 -0.0467 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7369 7.0644 0.3444 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0998 12.3562 0.4065 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0672 14.7815 -1.4404 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1854 17.6688 -1.2081 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.0981 -0.2171 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9115 8.6288 0.8903 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0625 8.6151 -1.2017 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1522 18.9093 0.5228 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9165 14.3653 1.7849 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4311 4.8774 -0.7154 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2795 4.8919 1.3764 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5596 2.1675 0.4699 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6192 2.4459 1.2163 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6142 0.0000 -1.1794 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6739 0.2784 -0.4331 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0277 0.3794 -2.4981 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2311 17.6426 1.6896 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 27 1 0 0 0 0 2 3 2 0 0 0 0 2 18 1 0 0 0 0 3 4 1 0 0 0 0 3 17 1 0 0 0 0 4 6 2 0 0 0 0 4 28 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 7 9 2 0 0 0 0 7 15 1 0 0 0 0 8 10 2 0 0 0 0 8 9 1 0 0 0 0 8 29 1 0 0 0 0 11 15 1 0 0 0 0 11 21 1 0 0 0 0 11 13 2 0 0 0 0 12 21 2 0 0 0 0 12 20 1 0 0 0 0 12 26 1 0 0 0 0 13 14 1 0 0 0 0 13 30 1 0 0 0 0 14 20 2 0 0 0 0 14 31 1 0 0 0 0 15 16 1 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 32 1 0 0 0 0 19 33 1 0 0 0 0 19 34 1 0 0 0 0 20 35 1 0 0 0 0 21 36 1 0 0 0 0 22 23 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 24 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 24 25 1 0 0 0 0 25 41 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 26 44 1 0 0 0 0 M END > (385) 384 > (385) C18H19N3O4 > (385) 341.3658 > (385) FGFR-P384 > (385) Anilinoquinazoline deriv. 12 > (385) FGFR-1 Tyrosine Kinase > (385) 7000 > (385) BINDDB > (385) <2007 > (385) P > (385) TRAIN $$$$ Anilinoquinazoline deriv. 13 csChFnd70/04170815452D 44 46 0 0 0 0 0 0 0 0999 V2000 3.2825 8.0050 -0.5002 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3240 6.5941 -0.7401 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5864 5.8509 -0.6310 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8121 6.5274 -0.2790 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5138 8.7174 -0.1412 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7938 7.9730 -0.0284 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5283 10.1775 0.1186 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9094 10.0358 0.5462 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7387 10.7739 0.4537 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9591 8.6812 0.3172 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3745 12.4211 0.1439 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2285 14.6200 0.5789 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6355 13.1172 -0.0560 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6907 14.5641 0.0620 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3155 10.9603 0.0254 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4222 10.4980 -0.1222 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6012 4.4484 -0.8747 O 0 0 0 0 0 0 0 0 0 0 0 0 2.1273 5.9031 -1.0883 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8744 6.7181 -1.1825 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4856 15.3142 0.3797 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1705 13.1762 0.4680 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9198 3.7499 -0.7470 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7298 2.1884 -1.0574 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3236 2.0095 -2.4877 O 0 0 0 0 0 0 0 0 0 0 0 0 5.1175 0.5814 -2.8885 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9431 12.4997 0.6687 F 0 0 0 0 0 0 0 0 0 0 0 0 3.5544 17.1268 0.5198 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.9252 15.2482 -0.1329 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3054 8.5688 -0.5915 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7802 5.9468 -0.1964 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8666 10.5728 0.8224 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2932 15.2055 0.8305 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5727 12.5327 -0.3028 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.0406 -1.4672 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6627 7.2091 -0.1730 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0050 7.5263 -1.9791 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6618 4.1984 -1.4907 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3188 3.8811 0.3152 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7142 1.6403 -0.8698 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9197 1.7603 -0.3752 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0893 0.0000 -2.7388 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2948 0.1200 -2.2442 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8113 0.5348 -3.9879 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0950 15.5270 -1.0923 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 29 1 0 0 0 0 2 3 2 0 0 0 0 2 18 1 0 0 0 0 3 4 1 0 0 0 0 3 17 1 0 0 0 0 4 6 2 0 0 0 0 4 30 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 7 9 2 0 0 0 0 7 15 1 0 0 0 0 8 10 2 0 0 0 0 8 9 1 0 0 0 0 8 31 1 0 0 0 0 11 15 1 0 0 0 0 11 21 1 0 0 0 0 11 13 2 0 0 0 0 12 21 2 0 0 0 0 12 20 1 0 0 0 0 12 32 1 0 0 0 0 13 14 1 0 0 0 0 13 33 1 0 0 0 0 14 20 2 0 0 0 0 14 28 1 0 0 0 0 15 16 1 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 19 34 1 0 0 0 0 19 35 1 0 0 0 0 19 36 1 0 0 0 0 20 27 1 0 0 0 0 21 26 1 0 0 0 0 22 23 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 24 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 24 25 1 0 0 0 0 25 41 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 28 44 1 0 0 0 0 M END > (386) 385 > (386) C18H17ClFN3O4 > (386) 393.8014 > (386) FGFR-P385 > (386) Anilinoquinazoline deriv. 13 > (386) FGFR-1 Tyrosine Kinase > (386) 7400 > (386) BINDDB > (386) <2007 > (386) P > (386) TRAIN $$$$ Anilinoquinazoline deriv. 20 csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 3.3905 8.5964 -0.5135 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4329 7.1393 -0.7600 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7364 6.3717 -0.6469 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0025 7.0703 -0.2854 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6623 9.3321 -0.1443 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9841 8.5634 -0.0286 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6776 10.8401 0.1225 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1876 9.2948 0.3274 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4862 13.1570 0.1495 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3064 15.4279 0.5978 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7887 13.8765 -0.0553 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8463 15.3658 0.0666 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4252 11.6485 0.0273 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5028 11.1711 -0.1246 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7509 4.9228 -0.8962 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6076 16.1411 0.3925 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2429 13.9376 0.4829 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1124 4.2015 -0.7641 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9154 2.5884 -1.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9741 13.2409 0.6887 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6840 18.0126 0.5368 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.1968 6.4258 -1.1186 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9033 7.2676 -1.2163 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1367 10.6938 0.5621 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9279 11.4562 0.4670 N 0 0 0 0 0 0 0 0 0 0 0 0 6.2945 2.3543 -5.0633 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6390 0.8657 -4.6882 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5327 0.8458 -3.0210 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5291 3.1088 -3.5912 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4832 2.3963 -2.5998 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3815 9.1788 -0.6077 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0020 6.4707 -0.2001 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3421 16.0354 0.8569 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7565 13.2727 -0.3094 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8600 15.9255 -0.0925 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8782 4.6631 -1.5333 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5252 4.3386 0.3323 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9320 2.0225 -0.8881 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0792 2.1479 -0.3763 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6851 7.7756 -0.1743 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0382 8.1014 -2.0397 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.5679 -1.5094 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1254 11.2485 0.8465 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3239 2.2195 -5.6232 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5443 2.9768 -5.7275 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5671 0.7572 -5.1684 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3468 0.0000 -5.0641 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5479 0.2944 -2.6782 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4817 0.3228 -2.5545 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6341 2.9401 -3.2140 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2945 4.2616 -3.6775 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 31 1 0 0 0 0 2 3 2 0 0 0 0 2 22 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 25 2 0 0 0 0 7 13 1 0 0 0 0 8 24 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 16 2 0 0 0 0 12 35 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 21 1 0 0 0 0 17 20 1 0 0 0 0 18 19 1 0 0 0 0 18 36 1 0 0 0 0 18 37 1 0 0 0 0 19 30 1 0 0 0 0 19 38 1 0 0 0 0 19 39 1 0 0 0 0 22 23 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 27 28 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 30 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 30 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 M END > (390) 389 > (390) C21H22ClFN4O2 > (390) 416.8818 > (390) FGFR-P389 > (390) Anilinoquinazoline deriv. 20 > (390) FGFR-1 Tyrosine Kinase > (390) 9400 > (390) BINDDB > (390) <2007 > (390) P > (390) TRAIN $$$$ 1,6-naphthyridin 25 csChFnd70/04170815452D 86 89 0 0 0 0 0 0 0 0999 V2000 1.2247 19.3017 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7178 16.6882 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3199 17.4938 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7861 20.2376 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3839 19.3153 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8122 22.0633 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9451 21.8810 -0.0204 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4114 22.8850 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2478 17.5964 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8917 20.1724 -0.0291 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5124 24.8077 0.0077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6411 27.5680 -1.1672 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5436 25.7716 -1.1781 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5709 25.6550 1.2058 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6624 27.4518 1.2096 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7019 28.4070 0.0226 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6970 28.5088 -2.3237 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8597 30.3554 -2.2394 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6939 28.2791 2.3782 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7262 30.1331 2.3092 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6387 14.8849 -0.0252 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2428 13.8627 -0.0460 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7946 11.9272 -0.0521 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4700 10.8596 -0.0738 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0219 8.9240 -0.0799 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5442 22.7135 -0.0325 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0201 21.7733 -0.0528 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9511 20.1960 -0.0608 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5723 22.5813 -0.0647 N 0 0 3 0 0 0 0 0 0 0 0 0 12.2150 20.4224 -1.7158 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1766 21.5592 -0.0869 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7416 22.7832 -0.0965 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2488 20.4047 1.5283 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6970 7.8564 -0.1015 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9236 5.6031 1.1891 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4391 3.6792 1.0710 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3402 3.0106 0.0634 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8246 4.9345 0.1814 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2667 5.9980 -0.1074 N 0 0 0 0 0 0 0 0 0 0 0 0 5.9969 2.6156 1.3599 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5666 0.7573 1.3539 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 19.9845 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5005 16.7371 -0.0419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6206 22.8025 0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7179 25.1191 -2.1050 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3186 24.9120 2.1307 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7755 29.8074 0.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0402 30.9469 -3.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4543 30.8069 -0.9607 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2087 30.7208 -2.4630 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5981 30.6274 3.3086 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1834 30.5499 1.0360 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4219 30.6363 2.5299 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5215 14.3036 -0.0177 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9884 14.1780 -1.2069 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0103 14.1655 1.1041 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0493 11.6119 1.1090 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0273 11.6242 -1.2021 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2154 11.1748 -1.2348 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2374 11.1625 1.0763 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2763 8.6087 1.0812 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2544 8.6212 -1.2299 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5992 23.9717 -0.0262 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6274 23.8396 -0.0584 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1636 21.2448 -2.8665 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4087 19.6620 -1.7322 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1002 19.5505 -1.7089 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7142 23.5930 1.0638 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9351 22.0228 -0.1130 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6902 23.6056 -1.2472 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1339 19.5328 1.5352 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4424 19.6443 1.5119 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2214 21.2147 2.6888 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4426 8.1718 -1.2626 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4644 8.1593 1.0485 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7775 6.3949 0.9380 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4193 5.8865 2.4842 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4701 3.3749 2.0569 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9103 3.4034 -0.2126 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8443 2.7271 -1.2316 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4861 2.2189 0.3144 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3533 5.2103 1.4650 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7936 5.2389 -0.8043 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0036 0.4073 0.1035 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7425 0.0000 1.5706 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6343 0.4856 2.3837 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 42 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 5 2 0 0 0 0 3 43 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 44 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 26 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 45 1 0 0 0 0 14 15 1 0 0 0 0 14 46 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 47 1 0 0 0 0 17 18 1 0 0 0 0 18 48 1 0 0 0 0 18 49 1 0 0 0 0 18 50 1 0 0 0 0 19 20 1 0 0 0 0 20 51 1 0 0 0 0 20 52 1 0 0 0 0 20 53 1 0 0 0 0 21 22 1 0 0 0 0 21 54 1 0 0 0 0 22 23 1 0 0 0 0 22 55 1 0 0 0 0 22 56 1 0 0 0 0 23 24 1 0 0 0 0 23 57 1 0 0 0 0 23 58 1 0 0 0 0 24 25 1 0 0 0 0 24 59 1 0 0 0 0 24 60 1 0 0 0 0 25 34 1 0 0 0 0 25 61 1 0 0 0 0 25 62 1 0 0 0 0 26 27 1 0 0 0 0 26 63 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 29 31 1 0 0 0 0 29 64 1 0 0 0 0 30 31 1 0 0 0 0 30 65 1 0 0 0 0 30 66 1 0 0 0 0 30 67 1 0 0 0 0 31 32 1 0 0 0 0 31 33 1 0 0 0 0 32 68 1 0 0 0 0 32 69 1 0 0 0 0 32 70 1 0 0 0 0 33 71 1 0 0 0 0 33 72 1 0 0 0 0 33 73 1 0 0 0 0 34 39 1 0 0 0 0 34 74 1 0 0 0 0 34 75 1 0 0 0 0 35 39 1 0 0 0 0 35 36 1 0 0 0 0 35 76 1 0 0 0 0 35 77 1 0 0 0 0 36 40 1 0 0 0 0 36 78 1 0 0 0 0 36 79 1 0 0 0 0 37 40 1 0 0 0 0 37 38 1 0 0 0 0 37 80 1 0 0 0 0 37 81 1 0 0 0 0 38 39 1 0 0 0 0 38 82 1 0 0 0 0 38 83 1 0 0 0 0 40 41 1 0 0 0 0 41 84 1 0 0 0 0 41 85 1 0 0 0 0 41 86 1 0 0 0 0 M END > (40) 38 > (40) C31H45N7O3 > (40) 563.7416 > (40) FGFR-P38 > (40) 1,6-naphthyridine 25 > (40) FGFR-1 Tyrosine Kinase > (40) 70 > (40) BINDDB > (40) <2007 > (40) P > (40) TRAIN $$$$ Anilinoquinazoline deriv. 22 csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 3.3258 11.1470 -0.5037 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3674 9.7178 -0.7455 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6460 8.9648 -0.6346 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8879 9.6501 -0.2799 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5733 11.8687 -0.1416 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8698 11.1146 -0.0280 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5884 13.3481 0.1202 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0505 11.8321 0.3212 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4198 15.6207 0.1467 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2624 17.8483 0.5864 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6973 16.3266 -0.0542 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7539 17.7874 0.0653 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3599 14.1409 0.0268 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4551 13.6727 -0.1222 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6602 7.5436 -0.8790 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5389 18.5478 0.3850 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2001 16.3864 0.4738 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9957 6.8359 -0.7495 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8025 5.2537 -1.0613 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9556 15.7029 0.6755 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6138 20.3835 0.5266 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.1549 9.0178 -1.0972 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8860 9.8436 -1.1930 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0006 13.2045 0.5514 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8147 13.9523 0.4581 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2325 4.4960 -0.9226 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8060 2.4057 -0.4674 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6152 0.8398 -0.8580 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1180 0.6101 -1.2437 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3341 2.1737 -0.8569 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0469 2.9770 -1.2219 N 0 0 0 0 0 0 0 0 0 0 0 0 6.8885 0.0822 -0.5265 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3362 11.7182 -0.5961 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8684 9.0619 -0.1963 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3165 18.4442 0.8405 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6467 15.7341 -0.3035 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7482 18.3363 -0.0908 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7470 7.2889 -1.5041 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4007 6.9704 0.3260 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0512 4.8009 -0.3068 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3975 5.1192 -2.1367 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.1572 -1.4806 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6720 10.3419 -0.1710 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0183 10.6615 -2.0007 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9705 13.7486 0.8303 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9837 4.9490 -1.6771 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6375 4.6306 0.1528 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8608 2.9983 -0.7741 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9698 2.5020 0.6740 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7333 0.3957 -0.2549 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3948 0.7481 -1.9902 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9703 0.5118 -2.3871 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0461 0.0000 -0.9194 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5384 2.2662 0.2782 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2343 2.5970 -1.4479 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 33 1 0 0 0 0 2 3 2 0 0 0 0 2 22 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 34 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 25 2 0 0 0 0 7 13 1 0 0 0 0 8 24 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 35 1 0 0 0 0 11 12 1 0 0 0 0 11 36 1 0 0 0 0 12 16 2 0 0 0 0 12 37 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 21 1 0 0 0 0 17 20 1 0 0 0 0 18 19 1 0 0 0 0 18 38 1 0 0 0 0 18 39 1 0 0 0 0 19 26 1 0 0 0 0 19 40 1 0 0 0 0 19 41 1 0 0 0 0 22 23 1 0 0 0 0 23 42 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 26 31 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 31 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 32 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 29 32 1 0 0 0 0 29 30 1 0 0 0 0 29 52 1 0 0 0 0 29 53 1 0 0 0 0 30 31 1 0 0 0 0 30 54 1 0 0 0 0 30 55 1 0 0 0 0 M END > (392) 391 > (392) C22H24ClFN4O3 > (392) 446.908 > (392) FGFR-P391 > (392) Anilinoquinazoline deriv. 22 > (392) FGFR-1 Tyrosine Kinase > (392) 6700 > (392) BINDDB > (392) <2007 > (392) P > (392) TRAIN $$$$ Anilinoquinazoline deriv. 23 csChFnd70/04170815452D 58 61 0 0 0 0 0 0 0 0999 V2000 3.3704 12.5383 -0.5104 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4126 11.0898 -0.7555 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7083 10.3267 -0.6431 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9670 11.0212 -0.2837 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6347 13.2696 -0.1435 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9487 12.5055 -0.0284 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6499 14.7688 0.1218 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1451 13.2325 0.3255 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4656 17.0719 0.1487 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2929 19.3295 0.5942 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7603 17.7872 -0.0550 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8176 19.2678 0.0662 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4050 15.5723 0.0271 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4880 15.0978 -0.1238 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7228 8.8864 -0.8908 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5863 20.0383 0.3902 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2297 17.8480 0.4801 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0763 8.1693 -0.7596 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8805 6.5658 -1.0755 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9684 17.1553 0.6846 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6623 21.8988 0.5337 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.1839 10.3804 -1.1119 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8979 11.2173 -1.2090 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0946 14.6233 0.5588 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8928 15.3812 0.4643 N 0 0 0 0 0 0 0 0 0 0 0 0 7.3295 5.7980 -0.9349 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1336 4.1946 -1.2509 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9832 3.1897 -2.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8052 1.1626 -0.9511 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3409 1.8871 -1.1592 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5308 3.9348 -2.2393 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5250 3.4574 -1.1159 N 0 0 0 0 0 0 0 0 0 0 0 0 10.7782 1.6649 -2.0319 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3675 13.1172 -0.6041 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9606 10.4251 -0.1989 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3341 19.9333 0.8518 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7225 17.1869 -0.3076 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8254 19.8240 -0.0920 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8376 8.6283 -1.5242 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4867 8.3057 0.3304 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1191 6.1069 -0.3109 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4700 6.4295 -2.1655 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.5217 -1.5005 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6811 11.7223 -0.1733 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0320 12.0462 -2.0277 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0774 15.1747 0.8415 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0909 6.2570 -1.6996 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7399 5.9344 0.1549 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3723 3.7356 -0.4862 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7232 4.0583 -2.3409 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7135 3.4932 -2.8860 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4392 3.5157 -0.9902 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2269 1.4295 0.1100 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6836 0.0000 -1.0436 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8929 1.5737 -2.1967 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6138 1.5542 -0.3014 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6724 5.0967 -2.1698 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1018 3.6542 -3.2938 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 22 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 35 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 25 2 0 0 0 0 7 13 1 0 0 0 0 8 24 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 36 1 0 0 0 0 11 12 1 0 0 0 0 11 37 1 0 0 0 0 12 16 2 0 0 0 0 12 38 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 21 1 0 0 0 0 17 20 1 0 0 0 0 18 19 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 19 26 1 0 0 0 0 19 41 1 0 0 0 0 19 42 1 0 0 0 0 22 23 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 23 45 1 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 32 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 28 33 1 0 0 0 0 28 31 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 29 33 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 32 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 M END > (393) 392 > (393) C23H26ClFN4O3 > (393) 460.9348 > (393) FGFR-P392 > (393) Anilinoquinazoline deriv. 23 > (393) FGFR-1 Tyrosine Kinase > (393) 1500 > (393) BINDDB > (393) <2007 > (393) P > (393) TRAIN $$$$ Anilinoquinazoline deriv. 27 csChFnd70/04170815452D 46 49 0 0 0 0 0 0 0 0999 V2000 3.3587 8.3957 -0.5087 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4007 6.9523 -0.7529 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6920 6.1918 -0.6409 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9462 6.8839 -0.2827 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6186 9.1244 -0.1430 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9279 8.3630 -0.0283 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6338 10.6185 0.1214 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1203 9.0875 0.3244 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4536 12.9137 0.1481 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2848 15.1633 0.5922 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7438 13.6265 -0.0548 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8009 15.1018 0.0659 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3931 11.4192 0.0270 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4793 10.9464 -0.1234 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7064 4.7565 -0.8878 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5739 15.8697 0.3888 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2219 13.6869 0.4785 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0551 4.0419 -0.7570 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9650 12.9967 0.6822 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6495 17.7237 0.5318 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.1762 6.2454 -1.1081 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8948 7.0793 -1.2049 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0699 10.4736 0.5569 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8723 11.2287 0.4627 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8600 2.4440 -1.0718 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0786 0.5523 -0.0719 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7928 1.1061 0.2806 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2120 1.5062 -1.9931 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2426 1.7114 -0.9377 N 0 0 3 0 0 0 0 0 0 0 0 0 9.3072 0.8123 -1.4675 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3592 8.9726 -0.6021 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9364 6.2899 -0.1982 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3295 15.7651 0.8488 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7026 13.0283 -0.3065 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8051 15.6561 -0.0917 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8138 4.4992 -1.5190 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4641 4.1777 0.3292 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0284 7.9053 -2.0206 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.3861 -1.4953 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6787 7.5825 -0.1727 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0493 11.0230 0.8385 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1012 1.9867 -0.3098 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4509 2.3082 -2.1579 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8011 0.0000 0.6446 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2919 1.0781 1.3242 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0994 1.8574 -3.0906 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 31 1 0 0 0 0 2 3 2 0 0 0 0 2 21 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 24 2 0 0 0 0 7 13 1 0 0 0 0 8 23 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 16 2 0 0 0 0 12 35 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 20 1 0 0 0 0 17 19 1 0 0 0 0 18 25 1 0 0 0 0 18 36 1 0 0 0 0 18 37 1 0 0 0 0 21 22 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 25 29 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 26 30 1 0 0 0 0 26 27 2 0 0 0 0 26 44 1 0 0 0 0 27 29 1 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 28 30 2 0 0 0 0 28 46 1 0 0 0 0 M END > (397) 396 > (397) C20H17ClFN5O2 > (397) 413.838 > (397) FGFR-P396 > (397) Anilinoquinazoline deriv. 27 > (397) FGFR-1 Tyrosine Kinase > (397) 2600 > (397) BINDDB > (397) <2007 > (397) P > (397) TRAIN $$$$ Anilinoquinazoline deriv. 28 csChFnd70/04170815452D 53 56 0 0 0 0 0 0 0 0999 V2000 3.4057 6.9214 -0.5158 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4483 5.4578 -0.7634 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7577 4.6866 -0.6498 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0294 5.3884 -0.2867 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6833 7.6603 -0.1450 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0110 6.8882 -0.0287 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6987 9.1752 0.1231 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2200 7.6228 0.3289 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5019 11.5024 0.1502 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3168 13.7837 0.6005 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8102 12.2253 -0.0555 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8682 13.7213 0.0669 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4406 9.9871 0.0274 N 0 0 3 0 0 0 0 0 0 0 0 0 2.5140 9.5076 -0.1251 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7723 3.2312 -0.9002 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6238 14.4999 0.3943 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2530 12.2866 0.4851 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1399 2.5066 -0.7676 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9785 11.5868 0.6918 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7006 16.3799 0.5393 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.2067 4.7410 -1.1236 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9073 5.5866 -1.2217 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1689 9.0282 0.5647 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9545 9.7940 0.4692 N 0 0 0 0 0 0 0 0 0 0 0 0 5.9420 0.8864 -1.0868 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5091 0.6940 -2.6072 N 0 0 3 0 0 0 0 0 0 0 0 0 3.9659 0.6875 -3.0010 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5635 0.5173 -3.6774 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0378 0.5139 -3.3237 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0485 0.3352 -4.4162 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2514 0.1606 -6.1581 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1734 0.3326 -5.1309 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6356 0.1696 -5.7804 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3922 7.5063 -0.6105 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0335 4.7861 -0.2010 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3481 14.3938 0.8607 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7825 11.6186 -0.3108 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8864 14.2834 -0.0929 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9092 2.9703 -1.5402 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5546 2.6443 0.3338 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0428 6.4241 -2.0488 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 4.8837 -1.5162 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6882 6.0968 -0.1751 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1620 9.5854 0.8503 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9632 0.3178 -0.8920 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1021 0.4438 -0.3780 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6168 1.7925 -3.2483 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8040 0.0000 -3.9522 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3289 0.2655 -2.0955 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3831 0.6497 -2.2098 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1925 0.3312 -4.1525 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9596 0.0220 -7.2868 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0429 0.3242 -5.4473 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 21 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 35 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 24 2 0 0 0 0 7 13 1 0 0 0 0 8 23 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 36 1 0 0 0 0 11 12 1 0 0 0 0 11 37 1 0 0 0 0 12 16 2 0 0 0 0 12 38 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 20 1 0 0 0 0 17 19 1 0 0 0 0 18 25 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 21 22 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 28 1 0 0 0 0 26 27 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 32 2 0 0 0 0 28 29 1 0 0 0 0 29 30 2 0 0 0 0 29 50 1 0 0 0 0 30 33 1 0 0 0 0 30 51 1 0 0 0 0 31 33 2 0 0 0 0 31 32 1 0 0 0 0 31 52 1 0 0 0 0 32 53 1 0 0 0 0 M END > (398) 397 > (398) C23H21ClFN5O2 > (398) 453.9026 > (398) FGFR-P397 > (398) Anilinoquinazoline deriv. 28 > (398) FGFR-1 Tyrosine Kinase > (398) 1600 > (398) BINDDB > (398) <2007 > (398) P > (398) TRAIN $$$$ 1,6-naphthyridin 26 csChFnd70/04170815452D 83 85 0 0 0 0 0 0 0 0999 V2000 1.2745 16.0407 0.5318 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0314 13.5866 0.2940 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5077 14.5597 -0.0631 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6959 17.1398 0.1796 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3638 16.3862 -0.1277 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5145 18.9664 0.1220 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6002 19.1133 -0.5271 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9859 19.9553 -0.2355 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4904 14.3395 0.5751 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7415 17.4009 -0.4678 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8665 21.8867 -0.3120 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4684 24.4864 -1.3884 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5761 22.6814 -1.3197 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0400 22.9110 0.6293 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9250 24.7152 0.5547 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6434 25.5023 -0.4556 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2106 25.2626 -2.3713 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1752 27.1286 -2.3826 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0686 25.7152 1.4729 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8748 27.5664 1.3362 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1585 11.7767 0.3613 N 0 0 3 0 0 0 0 0 0 0 0 0 4.8439 10.9240 0.0554 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6247 8.9432 0.2035 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3848 8.0525 -0.1160 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1656 6.0719 0.0321 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0701 20.1128 -0.8855 N 0 0 3 0 0 0 0 0 0 0 0 0 8.6204 19.3284 -1.1683 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7317 17.7456 -1.1095 O 0 0 0 0 0 0 0 0 0 0 0 0 10.0473 20.2988 -1.5162 N 0 0 3 0 0 0 0 0 0 0 0 0 11.5835 18.2249 -3.3982 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7324 19.4463 -1.8237 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1245 20.8334 -2.1860 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2491 18.3902 -0.2078 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9257 5.1812 -0.2873 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3594 2.3903 -2.7408 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2932 2.3665 -0.7437 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7153 3.2795 -0.1452 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2648 2.7697 1.6488 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5589 0.9003 1.6527 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.5945 0.7739 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7486 13.9278 -0.2876 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2647 19.5796 0.3494 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6613 21.8914 -2.0465 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0378 22.2990 1.4165 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5566 26.9091 -0.5115 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1117 27.5780 -3.2155 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9747 27.6076 -1.0570 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4122 27.6237 -2.8840 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8671 28.2073 2.1307 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0280 27.9605 -0.0232 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5816 27.9435 1.7968 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1313 11.0785 0.6107 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3128 11.2534 -1.2478 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7849 11.3711 1.0255 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1557 8.6138 1.5067 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6835 8.4961 -0.7667 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8538 8.3821 -1.4192 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3260 8.4997 0.8542 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6967 5.7423 1.3352 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2246 5.6247 -0.9380 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9813 21.3758 -0.9324 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9585 21.5618 -1.5633 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2155 18.9771 -4.5494 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8374 17.5905 -3.6269 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5918 17.2365 -3.1401 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2305 21.7036 -1.0642 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3783 20.1990 -2.4147 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7564 21.5857 -3.3370 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2574 17.4020 0.0503 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5030 17.7558 -0.4365 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3552 19.2603 0.9139 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3947 5.5106 -1.5906 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8669 5.6283 0.6827 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4871 1.6449 -3.1871 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1693 1.8083 -3.2621 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4688 3.7348 -3.1958 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2639 1.0187 -0.2859 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4458 3.0197 -0.2228 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4270 2.8398 2.4681 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2713 3.6533 2.1578 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0894 0.5730 2.9563 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4866 0.7959 0.7221 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5978 0.0000 1.2826 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 40 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 5 2 0 0 0 0 3 41 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 42 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 26 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 17 1 0 0 0 0 13 43 1 0 0 0 0 14 15 1 0 0 0 0 14 44 1 0 0 0 0 15 16 2 0 0 0 0 15 19 1 0 0 0 0 16 45 1 0 0 0 0 17 18 1 0 0 0 0 18 46 1 0 0 0 0 18 47 1 0 0 0 0 18 48 1 0 0 0 0 19 20 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 20 51 1 0 0 0 0 21 22 1 0 0 0 0 21 52 1 0 0 0 0 22 23 1 0 0 0 0 22 53 1 0 0 0 0 22 54 1 0 0 0 0 23 24 1 0 0 0 0 23 55 1 0 0 0 0 23 56 1 0 0 0 0 24 25 1 0 0 0 0 24 57 1 0 0 0 0 24 58 1 0 0 0 0 25 34 1 0 0 0 0 25 59 1 0 0 0 0 25 60 1 0 0 0 0 26 27 1 0 0 0 0 26 61 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 29 31 1 0 0 0 0 29 62 1 0 0 0 0 30 31 1 0 0 0 0 30 63 1 0 0 0 0 30 64 1 0 0 0 0 30 65 1 0 0 0 0 31 32 1 0 0 0 0 31 33 1 0 0 0 0 32 66 1 0 0 0 0 32 67 1 0 0 0 0 32 68 1 0 0 0 0 33 69 1 0 0 0 0 33 70 1 0 0 0 0 33 71 1 0 0 0 0 34 37 1 0 0 0 0 34 72 1 0 0 0 0 34 73 1 0 0 0 0 35 36 1 0 0 0 0 35 74 1 0 0 0 0 35 75 1 0 0 0 0 35 76 1 0 0 0 0 36 37 1 0 0 0 0 36 77 1 0 0 0 0 36 78 1 0 0 0 0 37 38 1 0 0 0 0 38 39 1 0 0 0 0 38 79 1 0 0 0 0 38 80 1 0 0 0 0 39 81 1 0 0 0 0 39 82 1 0 0 0 0 39 83 1 0 0 0 0 M END > (41) 39 > (41) C30H44N6O3 > (41) 536.716 > (41) FGFR-P39 > (41) 1,6-naphthyridine 26 > (41) FGFR-1 Tyrosine Kinase > (41) 28 > (41) BINDDB > (41) <2007 > (41) P > (41) TRAIN $$$$ Anilinoquinazoline deriv. 30 csChFnd70/04170815452D 45 48 0 0 0 0 0 0 0 0999 V2000 3.3212 8.9116 -0.5030 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3627 7.4844 -0.7445 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6396 6.7323 -0.6337 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8798 7.4167 -0.2795 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5670 9.6322 -0.1414 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8618 8.8793 -0.0280 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5820 11.1096 0.1200 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0408 9.5956 0.3208 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4150 13.3791 0.1465 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2594 15.6036 0.5856 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6908 14.0840 -0.0542 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7473 15.5428 0.0652 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3552 11.9013 0.0267 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4517 11.4337 -0.1220 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6538 5.3131 -0.8779 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5339 16.3021 0.3845 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1971 14.1438 0.4731 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9875 4.6064 -0.7485 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9543 13.4613 0.6746 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6088 18.1354 0.5259 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.1520 6.7853 -1.0957 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8849 7.6100 -1.1914 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9910 10.9662 0.5507 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8068 11.7130 0.4575 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7946 3.0264 -1.0599 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4356 1.1704 -0.0890 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1618 2.3020 -0.9273 N 0 0 3 0 0 0 0 0 0 0 0 0 8.3090 2.6320 -1.5882 N 0 0 0 0 0 0 0 0 0 0 0 0 8.8186 0.8474 -0.2928 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3167 1.7848 -1.2332 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3329 9.4820 -0.5953 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8590 6.8293 -0.1960 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3147 16.1986 0.8394 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6389 13.4924 -0.3031 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7403 16.0909 -0.0906 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7377 5.0587 -1.5020 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3919 4.7407 0.3256 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.9245 -1.4786 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6711 8.1076 -0.1708 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0170 8.4268 -1.9981 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9595 11.5095 0.8292 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0442 2.5741 -0.3064 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3900 2.8921 -2.1339 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6998 0.6357 0.6063 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4048 0.0000 0.2060 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 31 1 0 0 0 0 2 3 2 0 0 0 0 2 21 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 24 2 0 0 0 0 7 13 1 0 0 0 0 8 23 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 16 2 0 0 0 0 12 35 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 20 1 0 0 0 0 17 19 1 0 0 0 0 18 25 1 0 0 0 0 18 36 1 0 0 0 0 18 37 1 0 0 0 0 21 22 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 25 27 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 26 27 1 0 0 0 0 26 29 2 0 0 0 0 26 44 1 0 0 0 0 27 28 1 0 0 0 0 28 30 2 0 0 0 0 29 30 1 0 0 0 0 29 45 1 0 0 0 0 M END > (401) 400 > (401) C19H16ClFN6O2 > (401) 414.8258 > (401) FGFR-P400 > (401) Anilinoquinazoline deriv. 30 > (401) FGFR-1 Tyrosine Kinase > (401) 1800 > (401) BINDDB > (401) <2007 > (401) P > (401) TRAIN $$$$ Anilinoquinazoline deriv. 35 csChFnd70/04170815452D 45 48 0 0 0 0 0 0 0 0999 V2000 3.5510 9.4721 -0.4666 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5895 7.9483 -0.6915 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2744 7.8825 -0.2335 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8828 10.2448 -0.1166 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2610 9.4439 0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9050 11.8226 0.1266 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5218 10.2123 0.3379 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6636 14.2386 0.1539 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0486 16.6694 -0.9758 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4027 14.9268 1.5383 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4659 16.4811 1.6591 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5998 12.6647 0.0273 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6383 12.1670 -0.1303 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7884 17.3506 0.4039 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9813 15.1161 -1.1061 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2299 14.4522 -2.4551 F 0 0 0 0 0 0 0 0 0 0 0 0 2.2950 7.1988 -1.0315 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9467 8.0762 -1.1336 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4743 11.6756 0.5516 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2142 12.4700 0.4531 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8817 19.4746 0.5765 Br 0 0 0 0 0 0 0 0 0 0 0 0 4.9485 7.1487 -0.5764 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9582 5.6334 -0.8050 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3783 4.8823 -0.6718 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1662 3.1949 -0.9652 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3923 0.8889 -0.1467 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9244 1.2393 0.0837 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6219 2.4250 -0.8287 N 0 0 3 0 0 0 0 0 0 0 0 0 8.8328 2.7596 -1.5563 N 0 0 0 0 0 0 0 0 0 0 0 0 9.9094 1.8645 -1.1752 N 0 0 0 0 0 0 0 0 0 0 0 0 3.0872 14.0787 2.7645 F 0 0 0 0 0 0 0 0 0 0 0 0 2.4990 10.0787 -0.5633 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3167 7.2580 -0.1471 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2952 17.3520 -1.9543 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2629 17.0165 2.7344 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7350 8.6291 -0.0561 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0765 8.9264 -2.0121 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.3421 -1.4104 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5098 12.2583 0.8204 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1657 5.3456 -1.4945 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8250 5.0482 0.4616 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3787 2.7317 -0.1425 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7195 3.0290 -2.0986 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0236 0.0000 0.3967 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1500 0.6838 0.8425 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 4 2 0 0 0 0 1 32 1 0 0 0 0 2 22 2 0 0 0 0 2 17 1 0 0 0 0 3 22 1 0 0 0 0 3 5 2 0 0 0 0 3 33 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 7 1 0 0 0 0 6 20 2 0 0 0 0 6 12 1 0 0 0 0 7 19 2 0 0 0 0 8 12 1 0 0 0 0 8 15 1 0 0 0 0 8 10 2 0 0 0 0 9 15 2 0 0 0 0 9 14 1 0 0 0 0 9 34 1 0 0 0 0 10 11 1 0 0 0 0 10 31 1 0 0 0 0 11 14 2 0 0 0 0 11 35 1 0 0 0 0 12 13 1 0 0 0 0 14 21 1 0 0 0 0 15 16 1 0 0 0 0 17 18 1 0 0 0 0 18 36 1 0 0 0 0 18 37 1 0 0 0 0 18 38 1 0 0 0 0 19 20 1 0 0 0 0 19 39 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 24 25 1 0 0 0 0 24 40 1 0 0 0 0 24 41 1 0 0 0 0 25 28 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 26 30 1 0 0 0 0 26 27 2 0 0 0 0 26 44 1 0 0 0 0 27 28 1 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 29 30 2 0 0 0 0 M END > (405) 404 > (405) C19H15BrF2N6O2 > (405) 477.2673 > (405) FGFR-P404 > (405) Anilinoquinazoline deriv. 35 > (405) FGFR-1 Tyrosine Kinase > (405) 6100 > (405) BINDDB > (405) <2007 > (405) P > (405) TRAIN $$$$ Anilinoquinazoline deriv. 4 csChFnd70/04170815452D 36 38 0 0 0 0 0 0 0 0999 V2000 3.2790 5.3613 -0.4975 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3203 3.9522 -0.7362 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5811 3.2099 -0.6273 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8055 3.8857 -0.2771 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5089 6.0731 -0.1400 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7874 5.3297 -0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5236 7.5317 0.1185 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9018 7.3903 0.5446 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7327 8.1275 0.4522 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9515 6.0374 0.3159 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3713 9.7725 0.1437 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2311 11.9685 0.5818 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1686 10.5275 0.4659 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6310 10.4684 -0.0542 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6866 11.9089 0.0631 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3124 8.3134 0.0253 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4202 7.8517 -0.1220 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5956 1.8087 -0.8691 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9125 1.1112 -0.7418 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1248 3.2618 -1.0829 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8735 4.0758 -1.1770 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4886 12.6588 0.3781 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5636 14.4683 0.5238 Cl 0 0 0 0 0 0 0 0 0 0 0 0 0.9415 9.8536 0.6646 F 0 0 0 0 0 0 0 0 0 0 0 0 2.3030 5.9244 -0.5886 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7724 3.3060 -0.1950 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8582 7.9269 0.8191 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2983 12.5561 0.8319 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5673 9.8845 -0.2995 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6669 12.4503 -0.0910 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7771 0.0000 -0.9615 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6532 1.5584 -1.4854 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3118 1.2433 0.3187 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.3989 -1.4605 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6626 4.5669 -0.1690 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0035 4.8825 -1.9732 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 25 1 0 0 0 0 2 3 2 0 0 0 0 2 20 1 0 0 0 0 3 4 1 0 0 0 0 3 18 1 0 0 0 0 4 6 2 0 0 0 0 4 26 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 10 1 0 0 0 0 7 9 2 0 0 0 0 7 16 1 0 0 0 0 8 10 2 0 0 0 0 8 9 1 0 0 0 0 8 27 1 0 0 0 0 11 16 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 22 1 0 0 0 0 12 28 1 0 0 0 0 13 24 1 0 0 0 0 14 15 1 0 0 0 0 14 29 1 0 0 0 0 15 22 2 0 0 0 0 15 30 1 0 0 0 0 16 17 1 0 0 0 0 18 19 1 0 0 0 0 19 31 1 0 0 0 0 19 32 1 0 0 0 0 19 33 1 0 0 0 0 20 21 1 0 0 0 0 21 34 1 0 0 0 0 21 35 1 0 0 0 0 21 36 1 0 0 0 0 22 23 1 0 0 0 0 M END > (407) 406 > (407) C16H13ClFN3O2 > (407) 333.749 > (407) FGFR-P406 > (407) Anilinoquinazoline deriv. 4 > (407) FGFR-1 Tyrosine Kinase > (407) 7000 > (407) BINDDB > (407) <2007 > (407) P > (407) TRAIN $$$$ 1,6-naphthyridin 27 csChFnd70/04170815452D 56 59 0 0 0 0 0 0 0 0999 V2000 1.2247 16.2969 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7176 13.6835 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3196 14.4896 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7854 17.2327 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3830 16.3109 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8108 19.0590 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9441 18.8773 -0.0204 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4088 19.8813 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2478 14.5916 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8910 17.1679 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5087 21.8037 0.0077 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6604 24.4426 1.2018 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5722 22.6531 1.2008 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5453 22.7684 -1.1829 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6439 24.5574 -1.1696 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6962 25.3935 0.0218 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6389 11.8805 -0.0252 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2431 10.8585 -0.0460 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7952 8.9231 -0.0521 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4705 7.8557 -0.0738 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5372 19.7075 -0.0317 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6975 5.6023 1.2169 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2133 3.6787 1.0987 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1142 3.0105 0.0911 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5984 4.9342 0.2092 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0405 5.9974 -0.0796 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7712 2.6154 1.3876 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3410 0.7571 1.3817 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9797 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5002 13.7331 -0.0425 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6189 19.7975 0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4836 25.1022 2.1259 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3252 21.9121 2.1229 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7237 22.1170 -2.1140 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8985 25.3062 -2.0916 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7690 26.7940 0.0277 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5218 11.2989 -0.0177 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9883 11.1740 -1.2070 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0103 11.1615 1.1040 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0499 8.6077 1.1090 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0279 8.6201 -1.2021 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2158 8.1711 -1.2348 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2378 8.1588 1.0763 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5996 19.0312 -0.0453 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5917 20.9658 -0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5514 6.3939 0.9658 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1932 5.8858 2.5118 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2445 3.3742 2.0845 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6846 3.4028 -0.1848 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6184 2.7271 -1.2038 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2603 2.2190 0.3421 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1271 5.2101 1.4927 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5672 5.2386 -0.7765 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7783 0.4071 0.1313 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5172 0.0000 1.5982 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4090 0.4854 2.4113 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 29 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 30 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 31 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 32 1 0 0 0 0 13 33 1 0 0 0 0 14 15 1 0 0 0 0 14 34 1 0 0 0 0 15 16 2 0 0 0 0 15 35 1 0 0 0 0 16 36 1 0 0 0 0 17 18 1 0 0 0 0 17 37 1 0 0 0 0 18 19 1 0 0 0 0 18 38 1 0 0 0 0 18 39 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 19 41 1 0 0 0 0 20 26 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 44 1 0 0 0 0 21 45 1 0 0 0 0 22 26 1 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 23 27 1 0 0 0 0 23 48 1 0 0 0 0 23 49 1 0 0 0 0 24 27 1 0 0 0 0 24 25 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 25 26 1 0 0 0 0 25 52 1 0 0 0 0 25 53 1 0 0 0 0 27 28 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 M END > (42) 40 > (42) C22H28N6 > (42) 376.5034 > (42) FGFR-P40 > (42) 1,6-naphthyridine 27 > (42) FGFR-1 Tyrosine Kinase > (42) 2200 > (42) BINDDB > (42) <2007 > (42) P > (42) TRAIN $$$$ Anilinoquinazoline deriv. 16 csChFnd70/04170815452D 45 47 0 0 0 0 0 0 0 0999 V2000 3.8617 9.4943 0.3972 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8095 7.9092 0.5730 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1910 7.0315 0.6492 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6175 7.7397 0.5498 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3115 10.2516 0.2921 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7089 9.3687 0.3688 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4109 11.8921 0.1091 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2007 11.6107 0.0981 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0941 10.0894 0.2681 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9997 14.2197 0.8493 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6467 16.5996 1.4724 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2024 14.6401 1.8528 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1249 16.0398 2.6647 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0743 12.8072 0.0285 N 0 0 3 0 0 0 0 0 0 0 0 0 3.1917 12.4677 -0.5968 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1091 5.4551 0.8249 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8457 17.0188 2.4731 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7167 15.2013 0.6652 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5561 4.6239 0.8951 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2308 2.8767 1.0932 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4539 2.2972 -0.2668 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0944 0.6675 -0.2013 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5419 14.7913 -0.3069 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7535 18.7753 3.4846 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.3019 16.4537 3.6492 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4039 7.1747 0.6753 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0392 8.1338 0.5904 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8856 12.5567 0.0132 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7918 10.1611 0.3343 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6726 7.0494 0.6107 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3437 12.1408 0.0227 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6501 17.3609 1.3288 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1973 13.8774 2.0015 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2082 4.8148 -0.1826 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2394 5.0437 1.8850 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3315 2.2550 1.2508 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4910 2.6958 2.1145 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5065 0.3187 -1.2762 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1717 0.0000 -0.0706 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3309 0.4406 0.7930 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1248 17.0512 3.1562 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.4032 0.6868 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0542 8.9790 1.5434 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0226 8.7509 -0.5241 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0106 13.8049 -0.1272 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 29 1 0 0 0 0 2 3 2 0 0 0 0 2 26 1 0 0 0 0 3 4 1 0 0 0 0 3 16 1 0 0 0 0 4 6 2 0 0 0 0 4 30 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 28 2 0 0 0 0 7 14 1 0 0 0 0 8 9 2 0 0 0 0 8 28 1 0 0 0 0 8 31 1 0 0 0 0 10 14 1 0 0 0 0 10 18 1 0 0 0 0 10 12 2 0 0 0 0 11 18 2 0 0 0 0 11 17 1 0 0 0 0 11 32 1 0 0 0 0 12 13 1 0 0 0 0 12 33 1 0 0 0 0 13 17 2 0 0 0 0 13 25 1 0 0 0 0 14 15 1 0 0 0 0 16 19 1 0 0 0 0 17 24 1 0 0 0 0 18 23 1 0 0 0 0 19 20 1 0 0 0 0 19 34 1 0 0 0 0 19 35 1 0 0 0 0 20 21 1 0 0 0 0 20 36 1 0 0 0 0 20 37 1 0 0 0 0 21 22 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 25 41 1 0 0 0 0 26 27 1 0 0 0 0 27 42 1 0 0 0 0 27 43 1 0 0 0 0 27 44 1 0 0 0 0 28 45 1 0 0 0 0 M END > (411) 410 > (411) C19H18ClFN2O4 > (411) 392.8136 > (411) FGFR-P410 > (411) Anilinoquinoline deriv. 16 > (411) FGFR-1 Tyrosine Kinase > (411) 1400 > (411) BINDDB > (411) <2007 > (411) P > (411) TRAIN $$$$ Anilinoquinazoline deriv. 17 csChFnd70/04170815452D 44 46 0 0 0 0 0 0 0 0999 V2000 3.8656 9.5043 0.3993 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8133 7.9176 0.5758 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1961 7.0389 0.6522 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6239 7.7478 0.5520 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3167 10.2621 0.2932 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7154 9.3783 0.3698 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4166 11.9041 0.1092 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1022 10.0993 0.2683 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0044 14.2342 0.8501 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6537 16.6162 1.4760 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2080 14.6554 1.8555 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1316 16.0522 2.6659 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0788 12.8203 0.0285 N 0 0 3 0 0 0 0 0 0 0 0 0 3.1953 12.4805 -0.5974 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1142 5.4610 0.8289 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8569 17.0314 2.4773 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7206 15.2178 0.6660 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5624 4.6289 0.8990 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2368 2.8801 1.0984 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4586 2.2995 -0.2625 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0987 0.6683 -0.1961 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5437 14.8095 -0.3068 F 0 0 0 0 0 0 0 0 0 0 0 0 3.7698 18.7885 3.4922 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.4063 7.1826 0.6793 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0403 8.1426 0.5942 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8929 12.5691 0.0125 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2090 11.6219 0.0975 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7946 10.1717 0.3363 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6800 7.0568 0.6129 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6578 17.3807 1.3345 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2035 13.8918 2.0045 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0682 16.3796 3.4481 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2150 4.8195 -0.1799 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2469 5.0495 1.8894 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3386 2.2578 1.2560 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4966 2.6995 2.1209 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1769 0.0000 -0.0653 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3349 0.4416 0.7996 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5098 0.3187 -1.2717 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.4113 0.6914 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0556 8.9890 1.5479 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0233 8.7597 -0.5217 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0181 13.8185 -0.1283 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3533 12.1524 0.0208 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 28 1 0 0 0 0 2 3 2 0 0 0 0 2 24 1 0 0 0 0 3 4 1 0 0 0 0 3 15 1 0 0 0 0 4 6 2 0 0 0 0 4 29 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 26 2 0 0 0 0 7 13 1 0 0 0 0 8 27 2 0 0 0 0 9 13 1 0 0 0 0 9 17 1 0 0 0 0 9 11 2 0 0 0 0 10 17 2 0 0 0 0 10 16 1 0 0 0 0 10 30 1 0 0 0 0 11 12 1 0 0 0 0 11 31 1 0 0 0 0 12 16 2 0 0 0 0 12 32 1 0 0 0 0 13 14 1 0 0 0 0 15 18 1 0 0 0 0 16 23 1 0 0 0 0 17 22 1 0 0 0 0 18 19 1 0 0 0 0 18 33 1 0 0 0 0 18 34 1 0 0 0 0 19 20 1 0 0 0 0 19 35 1 0 0 0 0 19 36 1 0 0 0 0 20 21 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 24 25 1 0 0 0 0 25 40 1 0 0 0 0 25 41 1 0 0 0 0 25 42 1 0 0 0 0 26 27 1 0 0 0 0 26 43 1 0 0 0 0 27 44 1 0 0 0 0 M END > (412) 411 > (412) C19H18ClFN2O3 > (412) 376.8142 > (412) FGFR-P411 > (412) Anilinoquinoline deriv. 17 > (412) FGFR-1 Tyrosine Kinase > (412) 9300 > (412) BINDDB > (412) <2007 > (412) P > (412) TRAIN $$$$ Sorafenib (BAY 439006) csChFnd70/04170815452D 48 50 0 0 0 0 0 0 0 0999 V2000 2.7801 9.0208 -1.6747 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9755 7.9390 -3.0920 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6121 7.5885 -3.7379 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0546 8.3179 -2.9690 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8621 9.4042 -1.5463 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2188 9.7537 -0.9008 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9955 9.4059 -0.9797 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1290 10.5211 0.4441 F 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.1948 -2.2742 F 0 0 0 0 0 0 0 0 0 0 0 0 0.2008 7.8596 -0.4642 F 0 0 0 0 0 0 0 0 0 0 0 0 1.1648 7.0193 -4.0611 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.3224 10.1449 -0.7640 N 0 0 3 0 0 0 0 0 0 0 0 0 8.8175 9.2453 -0.6769 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9304 7.8351 -1.3718 O 0 0 0 0 0 0 0 0 0 0 0 0 10.1875 9.9089 0.1803 N 0 0 3 0 0 0 0 0 0 0 0 0 11.7787 9.0331 0.1662 C 0 0 0 0 0 0 0 0 0 0 0 0 14.8865 9.1005 0.1391 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3188 9.9643 0.1523 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8159 7.2336 0.1734 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3843 6.3712 0.1601 C 0 0 0 0 0 0 0 0 0 0 0 0 14.9228 7.3024 0.1401 C 0 0 0 0 0 0 0 0 0 0 0 0 16.4668 6.4526 0.1264 O 0 0 0 0 0 0 0 0 0 0 0 0 16.9848 5.7050 -1.3798 C 0 0 0 0 0 0 0 0 0 0 0 0 18.4833 4.6996 -1.4459 C 0 0 0 0 0 0 0 0 0 0 0 0 16.0278 5.9181 -2.8946 C 0 0 0 0 0 0 0 0 0 0 0 0 16.5935 5.1373 -4.4067 C 0 0 0 0 0 0 0 0 0 0 0 0 18.9679 3.9565 -3.0150 C 0 0 0 0 0 0 0 0 0 0 0 0 18.0181 4.1994 -4.4305 N 0 0 0 0 0 0 0 0 0 0 0 0 20.5584 2.8837 -3.1090 C 0 0 0 0 0 0 0 0 0 0 0 0 21.4326 2.6567 -1.8184 O 0 0 0 0 0 0 0 0 0 0 0 0 21.0354 2.1596 -4.6256 N 0 0 3 0 0 0 0 0 0 0 0 0 22.6079 1.0990 -4.7184 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7612 6.7435 -4.8440 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3316 8.0436 -3.4732 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0656 10.5980 0.2053 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2581 11.3055 -0.2847 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0720 10.9928 0.8071 H 0 0 0 0 0 0 0 0 0 0 0 0 16.0846 9.8247 0.1283 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2907 11.3641 0.1515 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6184 6.5086 0.1900 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4134 4.9715 0.1658 H 0 0 0 0 0 0 0 0 0 0 0 0 19.2571 4.5007 -0.2963 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8562 6.6844 -2.8894 H 0 0 0 0 0 0 0 0 0 0 0 0 15.8546 5.2994 -5.5847 H 0 0 0 0 0 0 0 0 0 0 0 0 20.3376 2.3408 -5.6558 H 0 0 0 0 0 0 0 0 0 0 0 0 23.7253 1.8797 -4.3465 H 0 0 0 0 0 0 0 0 0 0 0 0 22.4875 0.0000 -3.8385 H 0 0 0 0 0 0 0 0 0 0 0 0 22.7810 0.6280 -6.0393 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 7 1 0 0 0 0 2 3 1 0 0 0 0 2 11 1 0 0 0 0 3 4 2 0 0 0 0 3 33 1 0 0 0 0 4 5 1 0 0 0 0 4 34 1 0 0 0 0 5 6 2 0 0 0 0 5 12 1 0 0 0 0 6 35 1 0 0 0 0 7 8 1 0 0 0 0 7 10 1 0 0 0 0 7 9 1 0 0 0 0 12 13 1 0 0 0 0 12 36 1 0 0 0 0 13 15 1 0 0 0 0 13 14 2 0 0 0 0 15 16 1 0 0 0 0 15 37 1 0 0 0 0 16 18 1 0 0 0 0 16 19 2 0 0 0 0 17 18 2 0 0 0 0 17 21 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 20 21 2 0 0 0 0 20 41 1 0 0 0 0 21 22 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 25 2 0 0 0 0 24 27 2 0 0 0 0 24 42 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 26 28 2 0 0 0 0 26 44 1 0 0 0 0 27 28 1 0 0 0 0 27 29 1 0 0 0 0 29 30 2 0 0 0 0 29 31 1 0 0 0 0 31 32 1 0 0 0 0 31 45 1 0 0 0 0 32 46 1 0 0 0 0 32 47 1 0 0 0 0 32 48 1 0 0 0 0 M END > (413) 412 > (413) C21H16ClF3N4O3 > (413) 464.8306 > (413) FGFR-P412 > (413) BAY 439006 > (413) FGFR-1 Tyrosine Kinase > (413) 580 > (413) BINDDB > (413) <2007 > (413) P > (413) TRAIN $$$$ 1,6-naphthyridin 28 csChFnd70/04170815452D 72 75 0 0 0 0 0 0 0 0999 V2000 1.2227 16.2719 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7133 13.6628 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3127 14.4672 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7815 17.2063 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3766 16.2855 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8075 19.0290 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9353 18.8469 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4041 19.8493 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 14.5696 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8819 17.1413 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5050 21.7687 0.0076 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6372 24.5191 -1.1626 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5380 22.7328 -1.1761 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5616 22.6165 1.2037 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6505 24.4033 1.2050 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6932 25.3530 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6343 11.8625 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2358 10.8420 -0.0464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7883 8.9097 -0.0533 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4609 7.8438 -0.0749 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6901 5.5938 1.2125 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2064 3.6732 1.0939 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1028 3.0061 0.0882 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5864 4.9267 0.2068 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0313 5.9886 -0.0815 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7615 2.6112 1.3822 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3319 0.7560 1.3756 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5318 19.6780 -0.0316 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0052 18.7393 -0.0507 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9364 17.1647 -0.0579 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5549 19.5460 -0.0617 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1565 18.5256 -0.0823 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1959 17.3899 -1.7079 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7189 19.7475 -0.0914 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2274 17.3737 1.5307 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9537 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4913 13.7116 -0.0419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6177 19.7670 0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8885 25.2673 -2.0791 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7131 22.0831 -2.1022 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3090 21.8765 2.1278 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4687 25.0615 2.1311 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7663 26.7511 0.0289 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5189 11.2821 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9803 11.1572 -1.2053 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0017 11.1440 1.1019 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0440 8.5946 1.1057 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0224 8.6076 -1.2017 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2054 8.1590 -1.2339 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2268 8.1459 1.0735 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5459 6.3844 0.9619 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1848 5.8764 2.5056 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2388 3.3691 2.0777 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6788 3.3983 -0.1878 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6081 2.7235 -1.2048 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2469 2.2155 0.3389 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1141 5.2016 1.4885 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5540 5.2308 -0.7770 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7702 0.4071 0.1269 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5059 0.0000 1.5917 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4010 0.4846 2.4033 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5866 20.9343 -0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6099 20.8023 -0.0559 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1454 18.2106 -2.8572 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3876 16.6308 -1.7234 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0829 16.5194 -1.7016 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6908 20.5566 1.0666 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9105 18.9883 -0.1068 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6683 20.5682 -1.2406 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1144 16.5032 1.5372 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4191 16.6146 1.5153 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1993 18.1828 2.6889 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 36 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 37 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 38 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 28 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 39 1 0 0 0 0 13 40 1 0 0 0 0 14 15 1 0 0 0 0 14 41 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 43 1 0 0 0 0 17 18 1 0 0 0 0 17 44 1 0 0 0 0 18 19 1 0 0 0 0 18 45 1 0 0 0 0 18 46 1 0 0 0 0 19 20 1 0 0 0 0 19 47 1 0 0 0 0 19 48 1 0 0 0 0 20 25 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 21 25 1 0 0 0 0 21 22 1 0 0 0 0 21 51 1 0 0 0 0 21 52 1 0 0 0 0 22 26 1 0 0 0 0 22 53 1 0 0 0 0 22 54 1 0 0 0 0 23 26 1 0 0 0 0 23 24 1 0 0 0 0 23 55 1 0 0 0 0 23 56 1 0 0 0 0 24 25 1 0 0 0 0 24 57 1 0 0 0 0 24 58 1 0 0 0 0 26 27 1 0 0 0 0 27 59 1 0 0 0 0 27 60 1 0 0 0 0 27 61 1 0 0 0 0 28 29 1 0 0 0 0 28 62 1 0 0 0 0 29 30 2 0 0 0 0 29 31 1 0 0 0 0 31 32 1 0 0 0 0 31 63 1 0 0 0 0 32 33 1 0 0 0 0 32 34 1 0 0 0 0 32 35 1 0 0 0 0 33 64 1 0 0 0 0 33 65 1 0 0 0 0 33 66 1 0 0 0 0 34 67 1 0 0 0 0 34 68 1 0 0 0 0 34 69 1 0 0 0 0 35 70 1 0 0 0 0 35 71 1 0 0 0 0 35 72 1 0 0 0 0 M END > (43) 41 > (43) C27H37N7O > (43) 475.6356 > (43) FGFR-P41 > (43) 1,6-naphthyridine 28 > (43) FGFR-1 Tyrosine Kinase > (43) 190 > (43) BINDDB > (43) <2007 > (43) P > (43) TRAIN $$$$ tetrahydroindole deriv. 4c csChFnd70/04170815452D 41 44 0 0 0 0 0 0 0 0999 V2000 3.8277 4.3514 -0.3650 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8164 2.7908 -0.7555 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8531 2.2243 -1.8546 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9065 3.2067 -2.5709 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8842 5.3511 -1.0800 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9361 4.7817 -2.1928 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1986 7.0403 -0.9341 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4764 7.3515 -2.0291 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8571 6.0018 -2.7262 N 0 0 3 0 0 0 0 0 0 0 0 0 7.0846 8.6124 -2.2644 O 0 0 0 0 0 0 0 0 0 0 0 0 4.4508 8.0965 0.0241 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0166 9.6341 0.1517 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1220 10.9741 0.2957 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6291 11.6505 0.2978 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1515 12.2219 0.3863 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7593 13.9273 0.5555 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0732 12.6550 0.3553 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5962 14.3464 0.0274 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2301 14.7940 1.0843 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5613 10.0812 0.1631 N 0 0 3 0 0 0 0 0 0 0 0 0 3.1333 0.0000 0.0337 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0654 2.2204 1.5871 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4812 1.5180 0.1462 S 0 0 0 0 0 0 0 0 0 0 0 0 0.8832 1.5062 -0.9354 N 0 0 0 0 0 0 0 0 0 0 0 0 3.0160 4.7951 0.4884 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8378 1.0020 -2.1540 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7092 2.7509 -3.4265 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6712 5.8934 -3.5029 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4330 7.7445 0.6753 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8654 11.0356 0.3305 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3687 14.3894 -0.5613 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8428 14.0716 1.4230 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6015 12.5792 1.5081 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9029 12.2620 -0.5225 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5791 15.1162 0.2610 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2499 14.4600 -1.1895 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0323 16.0467 1.0125 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5008 14.4759 2.2838 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4498 9.3868 0.0853 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8303 2.1363 -1.8725 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.8693 -0.6320 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 25 1 0 0 0 0 2 3 2 0 0 0 0 2 23 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 6 2 0 0 0 0 4 27 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 28 1 0 0 0 0 11 12 1 0 0 0 0 11 29 1 0 0 0 0 12 13 2 0 0 0 0 12 20 1 0 0 0 0 13 15 1 0 0 0 0 13 30 1 0 0 0 0 14 20 1 0 0 0 0 14 17 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 16 19 1 0 0 0 0 16 31 1 0 0 0 0 16 32 1 0 0 0 0 17 18 1 0 0 0 0 17 33 1 0 0 0 0 17 34 1 0 0 0 0 18 19 1 0 0 0 0 18 35 1 0 0 0 0 18 36 1 0 0 0 0 19 37 1 0 0 0 0 19 38 1 0 0 0 0 20 39 1 0 0 0 0 21 23 2 0 0 0 0 22 23 2 0 0 0 0 23 24 1 0 0 0 0 24 40 1 0 0 0 0 24 41 1 0 0 0 0 M END > (422) 421 > (422) C17H17N3O3S > (422) 343.3996 > (422) FGFR-P421 > (422) Indolin-2-one deriv. 4c > (422) FGFR-1 Tyrosine Kinase > (422) 220 > (422) BINDDB > (422) <2007 > (422) P > (422) TRAIN $$$$ tetrahydroindole deriv. 4d csChFnd70/04170815452D 39 42 0 0 0 0 0 0 0 0999 V2000 2.0578 4.8171 -0.3696 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0448 3.2395 -0.7643 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1047 2.6719 -1.8654 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1595 3.6569 -2.5616 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1222 5.8068 -1.0738 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1852 5.2338 -2.1779 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4409 7.4954 -0.9261 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7295 7.7990 -2.0092 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1121 6.4473 -2.6990 N 0 0 3 0 0 0 0 0 0 0 0 0 5.3452 9.0563 -2.2405 O 0 0 0 0 0 0 0 0 0 0 0 0 2.6889 8.5551 0.0238 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2564 10.0915 0.1506 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3636 11.4320 0.2947 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8705 12.1055 0.2947 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3940 12.6784 0.3839 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0040 14.3836 0.5526 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3150 13.1082 0.3511 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8397 14.7993 0.0226 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4755 15.2486 1.0797 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8008 10.5368 0.1613 N 0 0 3 0 0 0 0 0 0 0 0 0 0.9186 2.1745 -0.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.6698 0.9331 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9086 0.6523 -0.4060 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2401 5.2648 0.4754 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0945 1.4513 -2.1706 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9720 3.2056 -3.4096 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9337 6.3353 -3.4668 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6666 8.2067 0.6690 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1076 11.4948 0.3304 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6132 14.8454 -0.5637 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0884 14.5290 1.4203 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8433 13.0328 1.5033 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1438 12.7139 -0.5264 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8232 15.5680 0.2553 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4931 14.9126 -1.1937 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2788 16.5010 1.0079 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7466 14.9308 2.2789 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6882 9.8417 0.0831 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1493 0.0000 0.1108 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 24 1 0 0 0 0 2 3 2 0 0 0 0 2 21 1 0 0 0 0 3 4 1 0 0 0 0 3 25 1 0 0 0 0 4 6 2 0 0 0 0 4 26 1 0 0 0 0 5 7 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 27 1 0 0 0 0 11 12 1 0 0 0 0 11 28 1 0 0 0 0 12 13 2 0 0 0 0 12 20 1 0 0 0 0 13 15 1 0 0 0 0 13 29 1 0 0 0 0 14 20 1 0 0 0 0 14 17 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 16 19 1 0 0 0 0 16 30 1 0 0 0 0 16 31 1 0 0 0 0 17 18 1 0 0 0 0 17 32 1 0 0 0 0 17 33 1 0 0 0 0 18 19 1 0 0 0 0 18 34 1 0 0 0 0 18 35 1 0 0 0 0 19 36 1 0 0 0 0 19 37 1 0 0 0 0 20 38 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 39 1 0 0 0 0 M END > (423) 422 > (423) C18H16N2O3 > (423) 308.336 > (423) FGFR-P422 > (423) Indolin-2-one deriv. 4d > (423) FGFR-1 Tyrosine Kinase > (423) 310 > (423) BINDDB > (423) <2007 > (423) P > (423) TRAIN $$$$ Indolin-2-one deriv. 9a csChFnd70/04170815452D 45 48 0 0 0 0 0 0 0 0999 V2000 5.9295 3.8034 -0.3137 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8654 2.0687 -0.6935 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0415 1.3583 -1.8286 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2872 2.3691 -2.5922 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3725 4.1186 -2.2261 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1795 4.8332 -1.0763 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5957 6.6878 -0.9551 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0775 6.9350 -2.1023 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4740 5.4041 -2.8025 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8182 8.2906 -2.3712 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7692 7.9202 0.0252 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4581 9.5950 0.1471 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5270 11.1124 0.2982 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1815 10.0247 0.1458 N 0 0 3 0 0 0 0 0 0 0 0 0 4.5958 11.2800 0.3635 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9912 11.1820 2.2351 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0598 11.3497 2.3003 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2502 11.5292 0.9848 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2393 11.2996 3.8197 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3223 11.7547 0.2821 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7154 12.4479 0.3787 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3542 14.3481 0.5504 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9580 12.8041 0.3277 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5017 14.6862 -0.0516 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0170 15.2492 1.1156 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0093 4.3594 0.5675 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8967 1.2646 -0.1040 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9839 0.0000 -2.1187 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1973 1.8001 -3.4754 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4086 5.2203 -3.6098 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5956 7.6007 0.6981 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1329 9.2206 0.0615 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2146 12.5129 -0.1871 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0109 10.2385 -0.3721 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3724 9.9492 2.7857 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5762 12.2235 2.9706 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.4125 3.7967 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9344 14.8628 -0.6854 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3546 14.5539 1.5130 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5462 12.7074 1.5977 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8510 12.3294 -0.6446 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6201 15.4969 0.1934 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1185 14.8127 -1.3953 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8498 16.6391 1.0247 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3111 14.8992 2.4419 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 26 1 0 0 0 0 2 3 2 0 0 0 0 2 27 1 0 0 0 0 3 4 1 0 0 0 0 3 28 1 0 0 0 0 4 5 2 0 0 0 0 4 29 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 30 1 0 0 0 0 11 12 1 0 0 0 0 11 31 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 32 1 0 0 0 0 15 16 1 0 0 0 0 15 33 1 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 16 35 1 0 0 0 0 16 36 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 37 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 M END > (429) 428 > (429) C20H20N2O3 > (429) 336.3896 > (429) FGFR-P428 > (429) Indolin-2-one deriv. 9a > (429) FGFR-1 Tyrosine Kinase > (429) 270 > (429) BINDDB > (429) <2007 > (429) P > (429) TRAIN $$$$ Indolin-2-one deriv. 9b csChFnd70/04170815452D 45 48 0 0 0 0 0 0 0 0999 V2000 5.5964 3.5884 -0.2957 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5357 1.9512 -0.6540 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6456 1.2811 -1.7261 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8206 2.2353 -2.4459 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9007 3.8855 -2.1003 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7755 4.5596 -1.0154 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1681 6.3093 -0.9015 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5656 6.5428 -1.9840 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9401 5.0985 -2.6445 N 0 0 3 0 0 0 0 0 0 0 0 0 9.2646 7.8216 -2.2373 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3881 7.4719 0.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0378 9.0519 0.1378 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1592 10.4832 0.2797 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6635 9.4576 0.1368 N 0 0 3 0 0 0 0 0 0 0 0 0 4.3373 10.6414 0.3402 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7659 10.5487 2.1055 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9440 10.7067 2.1659 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1808 10.8760 0.9245 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1690 10.6594 3.5989 O 0 0 0 0 0 0 0 0 0 0 0 0 8.7960 11.0896 0.2652 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2800 11.7432 0.3556 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9391 13.5357 0.5172 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3389 12.0799 0.3082 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9084 13.8549 -0.0503 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5075 14.3860 1.0506 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9366 0.6225 0.3203 Br 0 0 0 0 0 0 0 0 0 0 0 0 4.7285 4.1132 0.5356 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5913 0.0000 -2.0007 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6795 1.6987 -3.2789 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8217 4.9251 -3.4059 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2809 7.1705 0.6576 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5610 8.6992 0.0574 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9779 11.8041 -0.1794 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7860 9.6586 -0.3541 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1253 9.3859 2.6251 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3173 11.5313 2.7997 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.7660 3.5764 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5434 14.0210 -0.6486 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9958 13.7300 1.4250 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8935 11.9888 1.5064 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1816 11.6318 -0.6087 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9633 14.6200 0.1809 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5471 13.9738 -1.3179 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3495 15.6972 0.9647 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7845 14.0561 2.3021 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 27 1 0 0 0 0 2 3 2 0 0 0 0 2 26 1 0 0 0 0 3 4 1 0 0 0 0 3 28 1 0 0 0 0 4 5 2 0 0 0 0 4 29 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 30 1 0 0 0 0 11 12 1 0 0 0 0 11 31 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 32 1 0 0 0 0 15 16 1 0 0 0 0 15 33 1 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 16 35 1 0 0 0 0 16 36 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 37 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 M END > (430) 429 > (430) C20H19BrN2O3 > (430) 415.2857 > (430) FGFR-P429 > (430) Indolin-2-one deriv. 9b > (430) FGFR-1 Tyrosine Kinase > (430) 270 > (430) BINDDB > (430) <2007 > (430) P > (430) TRAIN $$$$ Indolin-2-one deriv. 9c csChFnd70/04170815452D 50 53 0 0 0 0 0 0 0 0999 V2000 5.9295 4.7543 -0.3137 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8654 3.0198 -0.6935 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0416 2.3093 -1.8286 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2873 3.3201 -2.5923 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3726 5.0695 -2.2261 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1796 5.7842 -1.0763 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5958 7.6388 -0.9551 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0776 7.8861 -2.1023 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4740 6.3550 -2.8025 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8183 9.2417 -2.3713 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7693 8.8712 0.0252 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4582 10.5460 0.1471 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5271 12.0634 0.2982 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1816 10.9756 0.1458 N 0 0 3 0 0 0 0 0 0 0 0 0 4.5958 12.2311 0.3635 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9912 12.1330 2.2351 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0599 12.3007 2.3004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2502 12.4803 0.9848 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2393 12.2506 3.8197 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3223 12.7058 0.2821 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7155 13.3989 0.3787 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3543 15.2991 0.5504 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9581 13.7552 0.3277 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5017 15.6372 -0.0516 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0171 16.2001 1.1156 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9388 0.0000 0.2307 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7810 2.5523 1.8102 O 0 0 0 0 0 0 0 0 0 0 0 0 4.2850 1.7078 0.2682 S 0 0 0 0 0 0 0 0 0 0 0 0 2.5823 1.7286 -1.0137 N 0 0 0 0 0 0 0 0 0 0 0 0 5.0093 5.3104 0.5675 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9840 0.9509 -2.1188 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1974 2.7509 -3.4754 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4086 6.1712 -3.6098 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5956 8.5518 0.6981 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1329 10.1715 0.0615 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2146 13.4639 -0.1871 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0109 11.1894 -0.3721 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3724 10.9002 2.7858 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5762 13.1746 2.9706 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.3635 3.7967 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9345 15.8138 -0.6854 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3546 15.5049 1.5130 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5463 13.6584 1.5977 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8511 13.2805 -0.6446 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6202 16.4479 0.1934 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1185 15.7638 -1.3953 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8499 17.5901 1.0247 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3111 15.8503 2.4420 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6047 2.3929 -2.0706 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5625 1.0767 -0.7077 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 28 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 5 2 0 0 0 0 4 32 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 35 1 0 0 0 0 15 16 1 0 0 0 0 15 36 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 38 1 0 0 0 0 16 39 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 40 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 28 2 0 0 0 0 27 28 2 0 0 0 0 28 29 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 M END > (431) 430 > (431) C20H21N3O5S > (431) 415.463 > (431) FGFR-P430 > (431) Indolin-2-one deriv. 9c > (431) FGFR-1 Tyrosine Kinase > (431) 200 > (431) BINDDB > (431) <2007 > (431) P > (431) TRAIN $$$$ Indolin-2-one deriv. 9d csChFnd70/04170815452D 48 51 0 0 0 0 0 0 0 0999 V2000 5.9281 5.2201 -0.3161 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8634 3.4662 -0.7015 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0569 2.7584 -1.8499 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2937 3.7778 -2.6018 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3723 5.5302 -2.2286 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1759 6.2442 -1.0768 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5934 8.0993 -0.9536 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0757 8.3439 -2.0998 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4692 6.8133 -2.8016 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8197 9.6979 -2.3670 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7673 9.3321 0.0263 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4581 11.0061 0.1493 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5286 12.5242 0.3004 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1818 11.4339 0.1492 N 0 0 3 0 0 0 0 0 0 0 0 0 4.5976 12.6941 0.3645 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9918 12.5959 2.2354 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0606 12.7657 2.2995 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2521 12.9466 0.9837 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2392 12.7159 3.8185 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3243 13.1636 0.2862 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7184 13.8585 0.3820 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3591 15.7588 0.5542 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9612 14.2112 0.3336 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5072 16.0938 -0.0449 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0225 16.6578 1.1208 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5427 2.3631 0.0997 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5083 2.9802 1.0970 O 0 0 0 0 0 0 0 0 0 0 0 0 4.4832 0.6707 -0.2743 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0079 5.7768 0.5646 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0067 1.4016 -2.1479 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2083 3.2173 -3.4857 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4045 6.6296 -3.6078 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5928 9.0138 0.6980 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1323 10.6289 0.0651 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2181 13.9275 -0.1859 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0120 11.6535 -0.3720 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3713 11.3626 2.7858 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5774 13.6365 2.9719 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.8300 3.7946 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9406 16.2744 -0.6815 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3592 15.9654 1.5162 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5483 14.1130 1.6039 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8544 13.7361 -0.6384 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6263 16.9031 0.2014 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1251 16.2214 -1.3888 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8568 18.0480 1.0303 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3153 16.3070 2.4470 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5948 0.0000 0.2823 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 29 1 0 0 0 0 2 3 2 0 0 0 0 2 26 1 0 0 0 0 3 4 1 0 0 0 0 3 30 1 0 0 0 0 4 5 2 0 0 0 0 4 31 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 32 1 0 0 0 0 11 12 1 0 0 0 0 11 33 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 34 1 0 0 0 0 15 16 1 0 0 0 0 15 35 1 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 16 38 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 39 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 27 2 0 0 0 0 26 28 1 0 0 0 0 28 48 1 0 0 0 0 M END > (432) 431 > (432) C21H20N2O5 > (432) 380.3994 > (432) FGFR-P431 > (432) Indolin-2-one deriv. 9d > (432) FGFR-1 Tyrosine Kinase > (432) 220 > (432) BINDDB > (432) <2007 > (432) P > (432) TRAIN $$$$ Indolin-2-one deriv. 9e csChFnd70/04170815452D 49 52 0 0 0 0 0 0 0 0999 V2000 5.9475 6.4761 -0.3123 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8844 4.7419 -0.6892 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0648 4.0297 -1.8285 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3113 5.0483 -2.5947 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3901 6.7969 -2.2276 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1957 7.5077 -1.0765 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6072 9.3638 -0.9551 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0879 9.6153 -2.1032 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4875 8.0857 -2.8047 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8257 10.9726 -2.3710 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7780 10.5934 0.0253 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4629 12.2706 0.1474 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5279 13.7852 0.2985 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1849 12.7047 0.1460 N 0 0 3 0 0 0 0 0 0 0 0 0 4.5961 13.9476 0.3636 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9919 13.8479 2.2352 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0600 14.0104 2.3004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2499 14.1878 0.9847 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2394 13.9580 3.8199 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3213 14.4356 0.2824 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7129 15.1243 0.3789 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3466 17.0234 0.5508 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9543 15.4892 0.3284 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4931 17.3702 -0.0506 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0068 17.9290 1.1160 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9961 2.3202 -2.1933 O 0 0 0 0 0 0 0 0 0 0 0 0 5.6808 1.3408 -1.3603 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0274 7.0320 0.5691 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9170 3.9375 -0.0980 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2234 4.4826 -3.4782 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4222 7.9046 -3.6124 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6055 10.2708 0.6986 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1383 11.9030 0.0614 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2116 15.1795 -0.1870 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0141 12.9046 -0.3721 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3762 12.6161 2.7856 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5739 14.8910 2.9707 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.0676 3.7967 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9253 17.5371 -0.6850 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3463 17.2264 1.5132 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5426 15.3937 1.5983 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8486 15.0170 -0.6440 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6094 18.1836 0.1949 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1097 17.4959 -1.3942 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8359 19.3185 1.0251 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3017 17.5797 2.4425 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8462 1.4231 0.0304 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4227 1.8524 -1.7128 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7700 0.0000 -1.7635 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 28 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 5 2 0 0 0 0 4 30 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 31 1 0 0 0 0 11 12 1 0 0 0 0 11 32 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 33 1 0 0 0 0 15 16 1 0 0 0 0 15 34 1 0 0 0 0 15 35 1 0 0 0 0 16 17 1 0 0 0 0 16 36 1 0 0 0 0 16 37 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 38 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 27 1 0 0 0 0 27 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 M END > (433) 432 > (433) C21H22N2O4 > (433) 366.4158 > (433) FGFR-P432 > (433) Indolin-2-one deriv. 9e > (433) FGFR-1 Tyrosine Kinase > (433) 1080 > (433) BINDDB > (433) <2007 > (433) P > (433) TRAIN $$$$ Indolin-2-one deriv. 9f csChFnd70/04170815452D 55 59 0 0 0 0 0 0 0 0999 V2000 6.0144 9.2128 -0.3123 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9525 7.4695 -0.6873 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1464 6.7499 -1.8389 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4034 7.7847 -2.6133 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4749 9.5422 -2.2427 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2692 10.2538 -1.0835 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6769 12.1220 -0.9615 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1667 12.3809 -2.1162 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5746 10.8439 -2.8237 N 0 0 3 0 0 0 0 0 0 0 0 0 9.9039 13.7500 -2.3851 O 0 0 0 0 0 0 0 0 0 0 0 0 6.8371 13.3574 0.0256 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5199 15.0467 0.1490 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5735 16.5684 0.3009 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2517 15.4899 0.1486 N 0 0 3 0 0 0 0 0 0 0 0 0 4.6288 16.7254 0.3649 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0195 16.6223 2.2479 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0748 16.7793 2.3120 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2598 16.9557 0.9875 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2480 16.7233 3.8406 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3826 17.2317 0.2868 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7611 17.9196 0.3833 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3860 19.8296 0.5565 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0224 18.2979 0.3339 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5516 20.1894 -0.0469 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0534 20.7463 1.1270 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0758 4.8723 -2.2387 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2686 4.1437 -3.3815 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1965 2.3956 -3.7490 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9433 1.3670 -2.9857 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7562 2.0832 -1.8505 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8208 3.8281 -1.4674 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0878 9.7723 0.5739 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9806 6.6596 -0.0901 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3236 7.2197 -3.5028 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5162 10.6657 -3.6362 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6576 13.0287 0.7024 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2141 14.6866 0.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2382 17.9640 -0.1890 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0470 15.6740 -0.3763 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4100 15.3837 2.8019 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6012 17.6739 2.9891 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.8294 3.8164 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9614 20.3455 -0.6873 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3780 20.0301 1.5245 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6144 18.2035 1.6123 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9245 17.8262 -0.6444 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6723 21.0119 0.2006 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1658 20.3149 -1.3993 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8768 22.1441 1.0360 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3504 20.3952 2.4620 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2469 4.9456 -3.9790 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1201 1.8297 -4.6343 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8912 0.0000 -3.2777 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7806 1.2741 -1.2584 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8973 4.3846 -0.5760 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 32 1 0 0 0 0 2 3 2 0 0 0 0 2 33 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 5 2 0 0 0 0 4 34 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 35 1 0 0 0 0 11 12 1 0 0 0 0 11 36 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 37 1 0 0 0 0 15 16 1 0 0 0 0 15 38 1 0 0 0 0 15 39 1 0 0 0 0 16 17 1 0 0 0 0 16 40 1 0 0 0 0 16 41 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 42 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 24 48 1 0 0 0 0 25 49 1 0 0 0 0 25 50 1 0 0 0 0 26 31 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 27 51 1 0 0 0 0 28 29 2 0 0 0 0 28 52 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 30 31 2 0 0 0 0 30 54 1 0 0 0 0 31 55 1 0 0 0 0 M END > (434) 433 > (434) C26H24N2O3 > (434) 412.4872 > (434) FGFR-P433 > (434) Indolin-2-one deriv. 9f > (434) FGFR-1 Tyrosine Kinase > (434) 1270 > (434) BINDDB > (434) <2007 > (434) P > (434) TRAIN $$$$ Indolin-2-one deriv. 9g csChFnd70/04170815452D 59 63 0 0 0 0 0 0 0 0999 V2000 5.9345 9.1450 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9733 7.6145 -0.0118 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3133 6.8815 -0.2886 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6149 7.6884 -0.5130 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5858 9.2305 -0.4617 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2335 9.9577 -0.1833 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5628 11.5692 -0.1997 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1643 11.6734 -0.5023 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7005 10.2858 -0.6435 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8817 12.8179 -0.6069 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5761 12.7271 0.0212 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1071 14.1974 0.1417 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3841 15.4721 -0.3439 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4375 14.6335 0.7697 N 0 0 3 0 0 0 0 0 0 0 0 0 4.8887 15.5451 -1.0971 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6693 15.7093 0.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1739 15.7823 -0.6749 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0920 15.7103 -2.0141 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9332 15.9271 0.1421 O 0 0 0 0 0 0 0 0 0 0 0 0 8.5455 16.1307 0.6732 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3018 16.6687 -0.0029 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0180 18.2952 -0.3000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8099 17.0973 1.2103 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6743 18.6246 0.4648 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0885 19.2121 0.6598 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3504 5.2335 -0.3434 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0507 4.4196 -0.1255 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0929 2.8806 -0.1781 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4277 2.1535 -0.4467 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7183 2.9608 -0.6625 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6853 4.4946 -0.6195 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8271 2.0824 0.0339 O 0 0 0 0 0 0 0 0 0 0 0 0 4.9521 0.4997 -0.0352 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8977 9.7138 0.2496 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9673 6.9820 0.1618 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6479 7.1144 -0.7267 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7333 10.0506 -0.8468 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3984 12.5054 0.1015 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1723 13.9762 1.2076 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8594 16.4980 -1.8455 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7052 14.5281 -1.7303 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6987 14.7565 0.8266 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8528 16.7264 0.7114 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 15.9690 -0.3905 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2123 18.5361 -1.4720 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8732 18.5693 -0.0107 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7444 17.2234 2.4140 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8683 16.5890 0.9095 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4556 19.3958 0.9788 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9268 18.5214 -0.7162 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0421 20.3745 0.3191 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7669 19.1194 1.8249 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0131 4.9868 0.0841 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4582 0.9536 -0.4868 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7542 2.3896 -0.8703 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6943 5.1222 -0.7942 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3632 0.1744 -1.1282 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7246 0.1178 0.8171 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8638 0.0000 0.1523 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 35 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 5 2 0 0 0 0 4 36 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 37 1 0 0 0 0 11 12 1 0 0 0 0 11 38 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 15 41 1 0 0 0 0 16 17 1 0 0 0 0 16 42 1 0 0 0 0 16 43 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 44 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 25 51 1 0 0 0 0 25 52 1 0 0 0 0 26 31 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 27 53 1 0 0 0 0 28 29 2 0 0 0 0 28 32 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 30 31 2 0 0 0 0 30 55 1 0 0 0 0 31 56 1 0 0 0 0 32 33 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > (435) 434 > (435) C27H26N2O4 > (435) 442.5134 > (435) FGFR-P434 > (435) Indolin-2-one deriv. 9g > (435) FGFR-1 Tyrosine Kinase > (435) 1350 > (435) BINDDB > (435) <2007 > (435) P > (435) TRAIN $$$$ Indolin-2-one deriv. 9h csChFnd70/04170815452D 59 63 0 0 0 0 0 0 0 0999 V2000 6.9347 9.5699 0.0473 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9801 7.7818 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5459 6.9254 -0.3375 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0667 7.8689 -0.5999 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0320 9.6705 -0.5405 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4521 10.5197 -0.2142 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8366 12.4027 -0.2331 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7079 12.5247 -0.5867 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3340 10.9036 -0.7537 N 0 0 3 0 0 0 0 0 0 0 0 0 11.5458 13.8621 -0.7086 O 0 0 0 0 0 0 0 0 0 0 0 0 7.6837 13.7552 0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3040 15.4732 0.1668 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4591 16.9626 -0.4000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8584 15.9827 0.9007 N 0 0 3 0 0 0 0 0 0 0 0 0 5.7118 17.0478 -1.2796 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2873 17.2391 0.0937 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5401 17.3243 -0.7859 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4441 17.2406 -2.3506 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0905 17.4932 0.1689 O 0 0 0 0 0 0 0 0 0 0 0 0 9.9844 17.7323 0.7883 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5313 18.3606 -0.0013 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1993 20.2610 -0.3481 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4619 18.8615 1.4154 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3031 20.6460 0.5445 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4500 21.3323 0.7736 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5897 5.0009 -0.4016 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8377 4.0258 0.9344 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8847 2.2275 0.8638 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6721 1.4019 -0.5227 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4175 2.3631 -1.8470 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3737 4.1549 -1.7973 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0645 4.8387 2.2971 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3242 3.7587 3.6133 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7231 10.2342 0.2919 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8047 7.0427 0.1892 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2739 7.1983 -0.8493 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5409 10.6291 -0.9917 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3079 13.4960 0.1199 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7171 15.2148 1.4118 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6773 18.1613 -2.1539 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4975 15.8596 -2.0197 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3219 16.1256 0.9680 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5016 18.4272 0.8339 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.5420 -0.4533 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4260 20.5427 -1.7172 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8618 20.5810 -0.0097 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3856 19.0088 2.8219 H 0 0 0 0 0 0 0 0 0 0 0 0 12.6984 18.2676 1.0638 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2162 21.5468 1.1449 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5978 20.5254 -0.8354 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3957 22.6904 0.3757 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0745 21.2237 2.1347 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3056 1.4703 1.8936 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7064 0.0000 -0.5727 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0305 1.7085 -2.9262 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9511 4.9007 -2.8362 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3219 2.9375 3.0416 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3352 2.9445 4.1797 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7508 4.5700 4.6225 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 35 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 5 2 0 0 0 0 4 36 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 37 1 0 0 0 0 11 12 1 0 0 0 0 11 38 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 15 41 1 0 0 0 0 16 17 1 0 0 0 0 16 42 1 0 0 0 0 16 43 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 44 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 25 51 1 0 0 0 0 25 52 1 0 0 0 0 26 31 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 27 32 1 0 0 0 0 28 29 2 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 30 31 2 0 0 0 0 30 55 1 0 0 0 0 31 56 1 0 0 0 0 32 33 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > (436) 435 > (436) C27H26N2O4 > (436) 442.5134 > (436) FGFR-P435 > (436) Indolin-2-one deriv. 9h > (436) FGFR-1 Tyrosine Kinase > (436) 80 > (436) BINDDB > (436) <2007 > (436) P > (436) TRAIN $$$$ Indolin-2-one deriv. 9i csChFnd70/04170815452D 59 63 0 0 0 0 0 0 0 0999 V2000 5.9338 10.4542 0.0405 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9726 8.9241 -0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3125 8.1913 -0.2891 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6138 8.9985 -0.5137 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5843 10.5402 -0.4623 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2323 11.2670 -0.1835 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5614 12.8783 -0.1996 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1627 12.9827 -0.5024 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6989 11.5955 -0.6434 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8799 14.1271 -0.6061 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5750 14.0357 0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1058 15.5059 0.1428 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3829 16.7804 -0.3424 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4362 15.9418 0.7708 N 0 0 3 0 0 0 0 0 0 0 0 0 4.8874 16.8534 -1.0942 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6689 17.0179 0.0814 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1734 17.0910 -0.6705 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0905 17.0190 -2.0095 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9332 17.2361 0.1471 O 0 0 0 0 0 0 0 0 0 0 0 0 8.5444 17.4390 0.6737 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3009 17.9767 -0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0171 19.6030 -0.2991 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8088 18.4051 1.2102 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6735 19.9318 0.4643 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0881 20.5197 0.6599 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3498 6.5440 -0.3440 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6861 5.8058 -0.6141 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7170 4.2738 -0.6645 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0883 4.1977 -0.1711 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0500 5.7296 -0.1193 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4194 3.4663 -0.4472 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4536 1.9569 -0.4980 O 0 0 0 0 0 0 0 0 0 0 0 0 6.0783 1.1960 -0.2649 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8971 11.0228 0.2498 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9669 8.2916 0.1619 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6467 8.4247 -0.7276 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7315 11.3603 -0.8468 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3975 13.8140 0.1027 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1707 15.2846 1.2083 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8577 17.8062 -1.8428 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7033 15.8366 -1.7274 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6987 16.0653 0.8298 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8528 18.0350 0.7144 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.2780 -0.3849 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2106 19.8435 -1.4710 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8727 19.8772 -0.0090 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7435 18.5317 2.4137 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8670 17.8964 0.9098 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4549 20.7028 0.9777 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9260 19.8281 -0.7165 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0418 21.6818 0.3191 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7674 20.4272 1.8249 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6956 6.4334 -0.7840 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7517 3.7015 -0.8736 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0810 3.5666 -0.0021 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0143 6.2981 0.0954 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6430 1.4752 0.8311 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2816 1.5326 -1.1137 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2616 0.0000 -0.3342 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 35 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 5 2 0 0 0 0 4 36 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 37 1 0 0 0 0 11 12 1 0 0 0 0 11 38 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 15 41 1 0 0 0 0 16 17 1 0 0 0 0 16 42 1 0 0 0 0 16 43 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 44 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 25 51 1 0 0 0 0 25 52 1 0 0 0 0 26 30 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 27 53 1 0 0 0 0 28 31 2 0 0 0 0 28 54 1 0 0 0 0 29 31 1 0 0 0 0 29 30 2 0 0 0 0 29 55 1 0 0 0 0 30 56 1 0 0 0 0 31 32 1 0 0 0 0 32 33 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > (437) 436 > (437) C27H26N2O4 > (437) 442.5134 > (437) FGFR-P436 > (437) Indolin-2-one deriv. 9i > (437) FGFR-1 Tyrosine Kinase > (437) 880 > (437) BINDDB > (437) <2007 > (437) P > (437) TRAIN $$$$ 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b csChFnd70/04170815452D 39 41 0 0 0 0 0 0 0 0999 V2000 5.6039 9.9881 0.5678 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7328 7.7058 0.1433 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3626 8.4457 0.4765 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4695 11.1265 0.8970 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1776 10.2603 0.2859 N 0 0 3 0 0 0 0 0 0 0 0 0 7.8702 8.7645 0.0169 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9198 11.6808 0.2689 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1956 12.8789 0.6279 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6098 11.7811 -0.1852 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0353 12.1349 -1.7553 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6229 12.2265 -2.1702 C 0 0 0 0 0 0 0 0 0 0 0 0 12.7897 11.9694 -1.0397 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3803 11.6193 0.5144 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7987 11.5301 0.9526 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9199 6.0697 -0.0400 N 0 0 3 0 0 0 0 0 0 0 0 0 5.6094 5.0602 0.1201 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1070 5.5756 -0.3345 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8145 4.5751 -0.1747 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0144 3.0618 0.4375 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5083 2.5450 0.8912 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8070 3.5368 0.7278 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1988 0.7729 -1.0381 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7662 0.6695 1.8396 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3616 1.7896 0.6406 S 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.7866 0.7286 O 0 0 0 0 0 0 0 0 0 0 0 0 8.8973 12.3854 -2.8617 F 0 0 0 0 0 0 0 0 0 0 0 0 10.4014 11.1951 2.4729 F 0 0 0 0 0 0 0 0 0 0 0 0 3.3757 10.8128 1.0865 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7656 12.2405 0.9392 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9535 12.4993 -3.3810 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0281 12.0422 -1.3727 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2993 11.4199 1.3892 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9598 5.6312 -0.2785 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9499 6.7576 -0.8119 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6461 4.9750 -0.5279 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6601 1.3626 1.3692 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9743 3.1304 1.0774 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9504 0.9503 -1.8951 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3520 0.0000 -1.1645 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 5 1 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 6 2 0 0 0 0 2 15 1 0 0 0 0 4 28 1 0 0 0 0 4 29 1 0 0 0 0 5 6 1 0 0 0 0 5 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 9 14 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 10 26 1 0 0 0 0 11 12 2 0 0 0 0 11 30 1 0 0 0 0 12 13 1 0 0 0 0 12 31 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 27 1 0 0 0 0 15 16 1 0 0 0 0 15 33 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 34 1 0 0 0 0 18 19 2 0 0 0 0 18 35 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 2 0 0 0 0 20 36 1 0 0 0 0 21 37 1 0 0 0 0 22 24 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 2 0 0 0 0 24 25 2 0 0 0 0 M END > (438) 437 > (438) C15H12F2N6O3S > (438) 394.355 > (438) FGFR-P437 > (438) JNJ-7706621 > (438) FGFR-2 Tyrosine Kinase > (438) 220 > (438) BINDDB > (438) <2007 > (438) P > (438) TRAIN $$$$ 1,6-naphthyridin 30 csChFnd70/04170815452D 56 58 0 0 0 0 0 0 0 0999 V2000 1.1276 15.2428 0.5726 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3364 12.5071 0.3582 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9726 13.1511 0.0429 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7361 16.0195 0.2618 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2057 14.9507 -0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9324 17.8276 0.2134 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9675 17.3443 -0.3623 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5662 18.4882 -0.1022 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9899 13.5498 0.6086 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7551 15.6546 -0.3116 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8440 20.3846 -0.1673 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4255 22.9039 0.7248 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1726 21.1381 0.7910 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7823 21.4202 -1.1928 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0474 23.1844 -1.2488 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3636 23.9257 -0.2899 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0901 10.7270 0.4152 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5567 9.5584 0.1427 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9385 7.6829 0.2713 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4701 6.4625 -0.0135 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5973 18.0130 -0.6772 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8518 4.5869 0.1151 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3225 3.4151 -0.1582 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5884 3.5712 1.2501 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2935 2.7305 0.7006 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7350 1.6184 -0.3496 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9595 1.3664 -2.1528 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.0384 0.7888 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0516 12.2870 -0.1576 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8407 18.6753 0.4159 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4543 23.4891 1.4669 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0023 20.3415 1.5839 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7546 20.8426 -1.9424 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2259 23.9880 -2.0433 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5661 25.3071 -0.3375 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9472 10.2586 0.6356 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1072 9.7853 -1.1352 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5379 9.7984 1.1264 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3880 7.4561 1.5491 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9574 7.4431 -0.7125 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0206 6.6894 -1.2913 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4513 6.7023 0.9703 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5685 17.2397 -0.8576 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7686 19.2553 -0.7174 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3013 4.3601 1.3930 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8707 4.3471 -0.8686 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8072 4.9344 1.5362 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0940 2.9231 2.4004 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0626 1.3844 0.3510 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8213 3.4206 -0.4099 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2115 2.7878 1.7690 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8296 0.7457 -0.1826 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7568 1.3373 0.6261 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7684 2.1129 -2.2607 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8799 1.8067 -3.1259 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6779 0.0000 -2.3566 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 28 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 29 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 30 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 31 1 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 35 1 0 0 0 0 17 18 1 0 0 0 0 17 36 1 0 0 0 0 18 19 1 0 0 0 0 18 37 1 0 0 0 0 18 38 1 0 0 0 0 19 20 1 0 0 0 0 19 39 1 0 0 0 0 19 40 1 0 0 0 0 20 22 1 0 0 0 0 20 41 1 0 0 0 0 20 42 1 0 0 0 0 21 43 1 0 0 0 0 21 44 1 0 0 0 0 22 23 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 26 1 0 0 0 0 23 24 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 24 48 1 0 0 0 0 25 49 1 0 0 0 0 25 50 1 0 0 0 0 25 51 1 0 0 0 0 26 27 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 27 54 1 0 0 0 0 27 55 1 0 0 0 0 27 56 1 0 0 0 0 M END > (45) 43 > (45) C22H29N5 > (45) 363.5046 > (45) FGFR-P43 > (45) 1,6-naphthyridine 30 > (45) FGFR-1 Tyrosine Kinase > (45) 7300 > (45) BINDDB > (45) <2007 > (45) P > (45) TRAIN $$$$ 1,6-naphthyridin 31 csChFnd70/04170815452D 72 74 0 0 0 0 0 0 0 0999 V2000 1.1316 15.2943 0.5750 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3445 12.5494 0.3597 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9864 13.1954 0.0434 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7459 16.0737 0.2631 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2206 15.0011 -0.0117 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9434 17.8875 0.2145 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9883 17.4018 -0.3632 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5839 18.5497 -0.1024 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9936 13.5958 0.6111 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7751 15.7074 -0.3123 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8637 20.4524 -0.1678 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0609 23.2632 -1.2470 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7943 21.4930 -1.1911 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1926 21.2087 0.7994 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4470 22.9804 0.7332 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3860 24.0056 -0.2898 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0972 10.7632 0.4164 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5687 9.5904 0.1428 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9481 7.7085 0.2710 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4847 6.4838 -0.0147 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8641 4.6018 0.1134 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3395 3.4260 -0.1608 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6095 3.5820 1.2526 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3206 2.7382 0.7013 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7497 1.6230 -0.3535 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9721 1.3710 -2.1632 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6297 18.0747 -0.6802 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9835 16.9960 -0.9319 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7676 15.4338 -0.8813 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5768 17.6492 -1.2396 N 0 0 3 0 0 0 0 0 0 0 0 0 12.0484 16.4765 -1.5132 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6908 15.3219 -3.0886 C 0 0 0 0 0 0 0 0 0 0 0 0 13.6933 17.5423 -1.8333 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2983 15.3411 0.0967 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.0925 0.7920 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0690 12.3280 -0.1574 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8484 18.7385 0.4177 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2331 24.0705 -2.0393 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7592 20.9146 -1.9390 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0213 20.4096 1.5992 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4763 23.5678 1.4819 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5896 25.3917 -0.3372 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9503 10.2933 0.6370 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1214 9.8185 -1.1394 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5530 9.8307 1.1301 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3953 7.4806 1.5532 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9637 7.4683 -0.7163 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0374 6.7117 -1.2969 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4690 6.7240 0.9727 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3114 4.3739 1.3956 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8798 4.3616 -0.8739 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8294 4.9495 1.5402 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1132 2.9312 2.4066 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2416 2.7952 1.7737 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0886 1.3876 0.3500 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8505 3.4308 -0.4127 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8480 0.7472 -0.1861 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7681 1.3409 0.6251 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6893 0.0000 -2.3683 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7770 2.1203 -2.2715 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8958 1.8131 -3.1394 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8019 19.3212 -0.7206 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7491 18.8956 -1.2801 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5129 16.1308 -4.2355 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7858 14.4495 -3.2923 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5191 14.5626 -2.8607 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9480 18.3649 -0.7109 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7881 16.6698 -2.0368 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5153 18.3511 -2.9803 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1264 14.5821 0.3247 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3932 14.4687 -0.1068 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5531 16.1637 1.2190 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 35 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 36 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 37 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 27 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 38 1 0 0 0 0 13 39 1 0 0 0 0 14 15 1 0 0 0 0 14 40 1 0 0 0 0 15 16 2 0 0 0 0 15 41 1 0 0 0 0 16 42 1 0 0 0 0 17 18 1 0 0 0 0 17 43 1 0 0 0 0 18 19 1 0 0 0 0 18 44 1 0 0 0 0 18 45 1 0 0 0 0 19 20 1 0 0 0 0 19 46 1 0 0 0 0 19 47 1 0 0 0 0 20 21 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 21 22 1 0 0 0 0 21 50 1 0 0 0 0 21 51 1 0 0 0 0 22 25 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 52 1 0 0 0 0 23 53 1 0 0 0 0 24 54 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 25 26 1 0 0 0 0 25 57 1 0 0 0 0 25 58 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 26 61 1 0 0 0 0 27 28 1 0 0 0 0 27 62 1 0 0 0 0 28 29 2 0 0 0 0 28 30 1 0 0 0 0 30 31 1 0 0 0 0 30 63 1 0 0 0 0 31 32 1 0 0 0 0 31 33 1 0 0 0 0 31 34 1 0 0 0 0 32 64 1 0 0 0 0 32 65 1 0 0 0 0 32 66 1 0 0 0 0 33 67 1 0 0 0 0 33 68 1 0 0 0 0 33 69 1 0 0 0 0 34 70 1 0 0 0 0 34 71 1 0 0 0 0 34 72 1 0 0 0 0 M END > (46) 44 > (46) C27H38N6O > (46) 462.6368 > (46) FGFR-P44 > (46) 1,6-naphthyridine 31 > (46) FGFR-1 Tyrosine Kinase > (46) 300 > (46) BINDDB > (46) <2007 > (46) P > (46) TRAIN $$$$ 1,6-naphthyridin 32 csChFnd70/04170815452D 56 59 0 0 0 0 0 0 0 0999 V2000 1.2247 16.2964 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7174 13.6832 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3193 14.4891 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7852 17.2322 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3829 16.3103 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8107 19.0584 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9439 18.8768 -0.0204 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4086 19.8807 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2478 14.5911 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8908 17.1675 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5084 21.8028 0.0077 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6642 24.4947 1.5764 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5706 22.7038 1.5777 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5483 22.7179 -1.5548 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6420 24.5088 -1.5386 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6971 25.3947 0.0226 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6387 11.8801 -0.0252 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2429 10.8581 -0.0460 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7950 8.9227 -0.0521 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4704 7.8554 -0.0737 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5372 19.7068 -0.0322 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4809 21.6083 -3.5155 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.5296 21.5764 3.5289 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.6973 5.6021 1.2169 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2133 3.6784 1.0987 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1141 3.0103 0.0911 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5982 4.9340 0.2092 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0404 5.9973 -0.0796 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7711 2.6152 1.3876 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3411 0.7570 1.3816 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9791 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5000 13.7328 -0.0425 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6188 19.7969 0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7120 25.1936 2.7909 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6729 25.2188 -2.7473 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7698 26.7950 0.0284 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5217 11.2984 -0.0177 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9882 11.1735 -1.2070 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0101 11.1611 1.1040 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0497 8.6072 1.1090 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0277 8.6197 -1.2020 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2157 8.1708 -1.2348 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2376 8.1584 1.0762 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5994 19.0306 -0.0464 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5917 20.9651 -0.0265 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5512 6.3936 0.9657 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1930 5.8856 2.5116 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2444 3.3739 2.0844 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6846 3.4025 -0.1848 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6184 2.7268 -1.2037 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2602 2.2189 0.3421 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1269 5.2099 1.4926 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5669 5.2385 -0.7764 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7782 0.4070 0.1313 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5171 0.0000 1.5982 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4090 0.4852 2.4112 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 31 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 32 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 33 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 34 1 0 0 0 0 13 23 1 0 0 0 0 14 15 1 0 0 0 0 14 22 1 0 0 0 0 15 16 2 0 0 0 0 15 35 1 0 0 0 0 16 36 1 0 0 0 0 17 18 1 0 0 0 0 17 37 1 0 0 0 0 18 19 1 0 0 0 0 18 38 1 0 0 0 0 18 39 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 19 41 1 0 0 0 0 20 28 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 44 1 0 0 0 0 21 45 1 0 0 0 0 24 28 1 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 24 47 1 0 0 0 0 25 29 1 0 0 0 0 25 48 1 0 0 0 0 25 49 1 0 0 0 0 26 29 1 0 0 0 0 26 27 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 29 30 1 0 0 0 0 30 54 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 M END > (47) 45 > (47) C22H26Cl2N6 > (47) 445.3936 > (47) FGFR-P45 > (47) 1,6-naphthyridine 32 > (47) FGFR-1 Tyrosine Kinase > (47) 120 > (47) BINDDB > (47) <2007 > (47) P > (47) TRAIN $$$$ 1,6-naphthyridin 33 csChFnd70/04170815452D 66 69 0 0 0 0 0 0 0 0999 V2000 1.2228 16.2730 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 13.6638 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3129 14.4681 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7815 17.2074 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3767 16.2867 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8075 19.0303 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9356 18.8482 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4042 19.8507 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2459 14.5705 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8822 17.1425 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5052 21.7701 0.0076 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6624 24.4577 1.5738 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5678 22.6696 1.5751 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5455 22.6837 -1.5525 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6403 24.4719 -1.5363 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6956 25.3564 0.0225 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6344 11.8634 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2360 10.8427 -0.0464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7885 8.9103 -0.0533 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4612 7.8442 -0.0749 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4776 21.5758 -3.5103 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.5262 21.5439 3.5237 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.6902 5.5942 1.2125 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2066 3.6735 1.0939 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1031 3.0063 0.0882 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5868 4.9269 0.2068 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0315 5.9889 -0.0815 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7619 2.6115 1.3822 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3322 0.7562 1.3756 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5324 19.6792 -0.0316 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0058 18.7404 -0.0507 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9369 17.1658 -0.0579 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5557 19.5472 -0.0617 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1574 18.5267 -0.0823 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7198 19.7485 -0.0914 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9548 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4916 13.7127 -0.0419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6178 19.7684 0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7109 25.1557 2.7866 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6715 25.1808 -2.7433 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7696 26.7546 0.0284 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5190 11.2828 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9804 11.1578 -1.2054 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0020 11.1447 1.1020 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0441 8.5951 1.1057 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0226 8.6082 -1.2018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2057 8.1595 -1.2339 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2271 8.1464 1.0736 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5460 6.3847 0.9619 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1850 5.8767 2.5057 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2389 3.3693 2.0778 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6789 3.3984 -0.1879 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6084 2.7236 -1.2049 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2473 2.2157 0.3389 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1145 5.2020 1.4885 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5543 5.2312 -0.7771 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7704 0.4072 0.1269 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5063 0.0000 1.5917 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4011 0.4846 2.4034 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5872 20.9356 -0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6106 20.8035 -0.0559 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2078 17.7059 1.0668 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1854 17.7176 -1.2405 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9115 18.9892 -0.1068 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6692 20.5692 -1.2407 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6917 20.5576 1.0667 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 36 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 37 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 38 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 30 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 39 1 0 0 0 0 13 22 1 0 0 0 0 14 15 1 0 0 0 0 14 21 1 0 0 0 0 15 16 2 0 0 0 0 15 40 1 0 0 0 0 16 41 1 0 0 0 0 17 18 1 0 0 0 0 17 42 1 0 0 0 0 18 19 1 0 0 0 0 18 43 1 0 0 0 0 18 44 1 0 0 0 0 19 20 1 0 0 0 0 19 45 1 0 0 0 0 19 46 1 0 0 0 0 20 27 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 49 1 0 0 0 0 23 50 1 0 0 0 0 24 28 1 0 0 0 0 24 51 1 0 0 0 0 24 52 1 0 0 0 0 25 28 1 0 0 0 0 25 26 1 0 0 0 0 25 53 1 0 0 0 0 25 54 1 0 0 0 0 26 27 1 0 0 0 0 26 55 1 0 0 0 0 26 56 1 0 0 0 0 28 29 1 0 0 0 0 29 57 1 0 0 0 0 29 58 1 0 0 0 0 29 59 1 0 0 0 0 30 31 1 0 0 0 0 30 60 1 0 0 0 0 31 32 2 0 0 0 0 31 33 1 0 0 0 0 33 34 1 0 0 0 0 33 61 1 0 0 0 0 34 35 1 0 0 0 0 34 62 1 0 0 0 0 34 63 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 35 66 1 0 0 0 0 M END > (48) 46 > (48) C25H31Cl2N7O > (48) 516.4722 > (48) FGFR-P46 > (48) 1,6-naphthyridine 33 > (48) FGFR-1 Tyrosine Kinase > (48) 32 > (48) BINDDB > (48) <2007 > (48) P > (48) TRAIN $$$$ Pyrazine-Pyridine Biheteroaryl 39 csChFnd70/04170815452D 46 48 0 0 0 0 0 0 0 0999 V2000 0.9994 12.1669 0.1376 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2273 10.0688 0.3104 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5101 10.8129 0.2865 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2779 12.9190 0.1130 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0080 10.7650 0.2355 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5047 12.2254 0.1880 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8797 10.0312 0.3711 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1689 10.7657 0.3480 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4455 8.6782 0.5224 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2088 7.8669 0.5581 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8967 8.5490 0.4815 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3879 10.0771 0.4228 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5398 15.1584 0.1138 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7192 16.4087 -0.6541 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6264 14.6703 0.9905 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8833 15.4258 1.0915 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0618 16.6677 0.3217 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9800 17.1605 -0.5485 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2061 18.7237 -1.5077 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.2667 14.3958 0.0095 N 0 0 3 0 0 0 0 0 0 0 0 0 6.2828 6.3851 0.6634 N 0 0 3 0 0 0 0 0 0 0 0 0 7.6702 5.6768 0.7368 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4526 4.0664 0.8462 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9016 3.3267 0.9229 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6839 1.7164 1.0322 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0374 1.0254 1.1039 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.7321 0.0814 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2300 8.9218 0.3899 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1681 11.9126 0.2673 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4678 8.1558 0.5813 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9171 7.9478 0.5069 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8751 16.7933 -1.3333 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4880 13.7008 1.5930 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7278 15.0464 1.7732 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0457 17.2569 0.4032 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3752 14.8965 -0.1351 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4154 5.8253 0.6878 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2802 5.9206 -0.2196 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2477 6.0533 1.6704 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8427 3.8225 1.8027 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8752 3.6899 -0.0872 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5115 3.5705 -0.0335 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4791 3.7031 1.8563 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0741 1.4724 1.9888 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1065 1.3399 0.0989 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9808 0.0000 1.1749 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 27 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 29 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 30 1 0 0 0 0 10 11 1 0 0 0 0 10 21 1 0 0 0 0 11 31 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 17 35 1 0 0 0 0 18 19 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 21 37 1 0 0 0 0 22 23 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 26 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 46 1 0 0 0 0 M END > (480) 479 > (480) C19H20ClN5O > (480) 369.8529 > (480) FGFR-P479 > (480) Pyrazine-Pyridine Biheteroaryl 39 > (480) FGFR-2 Tyrosine Kinase > (480) 2360 > (480) BINDDB > (480) <2007 > (480) P > (480) TRAIN $$$$ 1,6-naphthyridin 34 csChFnd70/04170815452D 72 75 0 0 0 0 0 0 0 0999 V2000 1.2228 16.2729 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 13.6637 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3130 14.4680 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7814 17.2074 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3767 16.2866 -0.0180 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8075 19.0303 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9357 18.8481 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4042 19.8506 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 14.5704 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8822 17.1423 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5052 21.7699 0.0076 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6625 24.4576 1.5738 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5678 22.6694 1.5751 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5455 22.6835 -1.5524 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6403 24.4717 -1.5362 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6957 25.3563 0.0225 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6344 11.8633 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2361 10.8426 -0.0464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7885 8.9101 -0.0533 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4612 7.8442 -0.0749 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4776 21.5756 -3.5103 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.5262 21.5437 3.5237 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.6902 5.5942 1.2125 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2065 3.6736 1.0939 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1032 3.0062 0.0882 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5868 4.9269 0.2068 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0316 5.9889 -0.0815 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7619 2.6115 1.3822 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3323 0.7562 1.3756 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5323 19.6791 -0.0316 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0057 18.7404 -0.0507 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9368 17.1658 -0.0579 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5556 19.5471 -0.0617 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1573 18.5266 -0.0823 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1967 17.3908 -1.7080 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7197 19.7485 -0.0914 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2281 17.3746 1.5308 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.9546 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4916 13.7126 -0.0419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6178 19.7683 0.0258 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7110 25.1556 2.7866 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6715 25.1806 -2.7433 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7697 26.7544 0.0284 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5190 11.2828 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9805 11.1578 -1.2054 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0020 11.1447 1.1019 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0441 8.5950 1.1057 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0226 8.6081 -1.2018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2057 8.1595 -1.2339 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2271 8.1463 1.0735 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5460 6.3847 0.9619 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1850 5.8767 2.5057 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2389 3.3693 2.0777 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6789 3.3985 -0.1878 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6084 2.7236 -1.2049 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2472 2.2157 0.3389 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1145 5.2020 1.4885 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5543 5.2312 -0.7771 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7704 0.4072 0.1269 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5063 0.0000 1.5917 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4012 0.4846 2.4034 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5871 20.9355 -0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6106 20.8033 -0.0559 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1462 18.2116 -2.8573 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3884 16.6316 -1.7234 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0836 16.5203 -1.7017 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6916 20.5575 1.0667 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9114 18.9892 -0.1068 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6692 20.5691 -1.2407 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1150 16.5040 1.5373 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4197 16.6152 1.5154 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2001 18.1837 2.6890 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 38 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 39 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 40 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 30 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 41 1 0 0 0 0 13 22 1 0 0 0 0 14 15 1 0 0 0 0 14 21 1 0 0 0 0 15 16 2 0 0 0 0 15 42 1 0 0 0 0 16 43 1 0 0 0 0 17 18 1 0 0 0 0 17 44 1 0 0 0 0 18 19 1 0 0 0 0 18 45 1 0 0 0 0 18 46 1 0 0 0 0 19 20 1 0 0 0 0 19 47 1 0 0 0 0 19 48 1 0 0 0 0 20 27 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 23 27 1 0 0 0 0 23 24 1 0 0 0 0 23 51 1 0 0 0 0 23 52 1 0 0 0 0 24 28 1 0 0 0 0 24 53 1 0 0 0 0 24 54 1 0 0 0 0 25 28 1 0 0 0 0 25 26 1 0 0 0 0 25 55 1 0 0 0 0 25 56 1 0 0 0 0 26 27 1 0 0 0 0 26 57 1 0 0 0 0 26 58 1 0 0 0 0 28 29 1 0 0 0 0 29 59 1 0 0 0 0 29 60 1 0 0 0 0 29 61 1 0 0 0 0 30 31 1 0 0 0 0 30 62 1 0 0 0 0 31 32 2 0 0 0 0 31 33 1 0 0 0 0 33 34 1 0 0 0 0 33 63 1 0 0 0 0 34 35 1 0 0 0 0 34 36 1 0 0 0 0 34 37 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 35 66 1 0 0 0 0 36 67 1 0 0 0 0 36 68 1 0 0 0 0 36 69 1 0 0 0 0 37 70 1 0 0 0 0 37 71 1 0 0 0 0 37 72 1 0 0 0 0 M END > (49) 47 > (49) C27H35Cl2N7O > (49) 544.5258 > (49) FGFR-P47 > (49) 1,6-naphthyridine 34 > (49) FGFR-1 Tyrosine Kinase > (49) 26 > (49) BINDDB > (49) <2007 > (49) P > (49) TRAIN $$$$ Pyrazine-Pyridine Biheteroaryl 41 csChFnd70/04170815452D 47 49 0 0 0 0 0 0 0 0999 V2000 1.1151 12.1158 0.1536 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4850 9.7750 0.3464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9164 10.6052 0.3196 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5415 12.9550 0.1261 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1247 10.5518 0.2627 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9103 12.1812 0.2098 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4444 9.7330 0.4141 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8828 10.5526 0.3883 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3071 8.2235 0.5830 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9273 7.3183 0.6227 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4634 8.0793 0.5372 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2429 9.7842 0.4718 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9495 15.4536 0.1270 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1496 16.8486 -0.7299 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1618 14.9090 1.1051 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5641 15.7519 1.2178 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7633 17.1376 0.3589 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5563 17.6873 -0.6121 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8085 19.4315 -1.6821 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.5290 14.6027 0.0106 N 0 0 3 0 0 0 0 0 0 0 0 0 7.0098 5.6651 0.7402 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5579 4.8747 0.8222 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3151 3.0780 0.9441 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8673 2.2856 1.0263 N 0 0 0 0 0 0 0 0 0 0 0 0 10.6999 2.6931 2.5045 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6965 0.5572 0.8611 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.7465 0.0909 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4880 8.4954 0.4351 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8819 11.8321 0.2982 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4477 7.6407 0.6486 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3703 7.4086 0.5656 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2078 17.2777 -1.4876 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0073 13.8274 1.7773 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5065 15.3286 1.9783 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8610 17.7949 0.4499 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5344 15.1614 -0.1507 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0422 5.0404 0.7674 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2383 5.1468 -0.2450 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2021 5.2948 1.8636 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6345 2.8060 2.0113 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6707 2.6580 -0.0973 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9878 2.3176 3.5185 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8453 2.0907 2.5348 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8841 3.9734 2.5571 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1513 0.2846 -0.2810 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8633 0.0000 0.9263 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9481 0.1042 1.8155 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 27 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 29 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 30 1 0 0 0 0 10 11 1 0 0 0 0 10 21 1 0 0 0 0 11 31 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 17 35 1 0 0 0 0 18 19 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 21 37 1 0 0 0 0 22 23 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 26 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 M END > (481) 480 > (481) C19H21ClN6 > (481) 368.8681 > (481) FGFR-P480 > (481) Pyrazine-Pyridine Biheteroaryl 41 > (481) FGFR-2 Tyrosine Kinase > (481) 1400 > (481) BINDDB > (481) <2007 > (481) P > (481) TRAIN $$$$ Pyrazine-Pyridine Biheteroaryl 56 csChFnd70/04170815452D 51 54 0 0 0 0 0 0 0 0999 V2000 1.1152 16.1045 0.1536 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4852 13.7634 0.3464 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9167 14.5938 0.3196 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5417 16.9437 0.1261 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1247 14.5403 0.2627 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9106 16.1698 0.2098 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4448 13.7215 0.4141 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8834 14.5411 0.3883 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3077 12.2118 0.5830 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9279 11.3066 0.6227 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4638 12.0677 0.5372 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2435 13.7727 0.4718 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9498 19.4425 0.1270 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1500 20.8376 -0.7299 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1622 18.8978 1.1052 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5647 19.7409 1.2179 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7639 21.1266 0.3589 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5567 21.6763 -0.6121 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8089 23.4206 -1.6823 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.5292 18.5915 0.0106 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5585 8.8629 0.8222 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0104 9.6532 0.7402 N 0 0 3 0 0 0 0 0 0 0 0 0 8.3157 7.0659 0.9441 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9326 6.2406 1.0298 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6933 4.4707 1.1499 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6065 3.5498 -0.2061 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5643 3.7445 2.6228 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3451 2.1135 2.6759 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2629 1.2710 1.2690 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3969 2.0004 -0.1105 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.7353 0.0909 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4882 12.4837 0.4351 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8825 15.8207 0.2982 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4485 11.6290 0.6486 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3707 11.3968 0.5656 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2080 21.2668 -1.4878 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0077 17.8161 1.7775 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5071 19.3176 1.9785 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8616 21.7840 0.4499 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5346 19.1502 -0.1507 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2391 9.1350 -0.2450 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2029 9.2830 1.8638 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0426 9.0286 0.7674 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6351 6.7939 2.0115 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6713 6.6459 -0.0973 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6130 6.5127 -0.0374 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5768 6.6607 2.0713 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7113 4.1057 -1.3575 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6335 4.4334 3.7027 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2402 1.5085 3.8022 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0923 0.0000 1.3002 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 31 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 33 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 34 1 0 0 0 0 10 11 1 0 0 0 0 10 22 1 0 0 0 0 11 35 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 36 1 0 0 0 0 15 16 2 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 38 1 0 0 0 0 17 18 2 0 0 0 0 17 39 1 0 0 0 0 18 19 1 0 0 0 0 20 40 1 0 0 0 0 21 22 1 0 0 0 0 21 23 1 0 0 0 0 21 41 1 0 0 0 0 21 42 1 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 44 1 0 0 0 0 23 45 1 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 24 47 1 0 0 0 0 25 26 2 0 0 0 0 25 27 1 0 0 0 0 26 30 1 0 0 0 0 26 48 1 0 0 0 0 27 28 2 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 29 30 2 0 0 0 0 29 51 1 0 0 0 0 M END > (482) 481 > (482) C23H21ClN6 > (482) 416.9121 > (482) FGFR-P481 > (482) Pyrazine-Pyridine Biheteroaryl 56 > (482) FGFR-2 Tyrosine Kinase > (482) 293 > (482) BINDDB > (482) <2007 > (482) P > (482) TRAIN $$$$ Pyrazine-Pyridine Biheteroaryl 57 csChFnd70/04170815452D 49 52 0 0 0 0 0 0 0 0999 V2000 1.1077 15.1589 0.1526 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4685 12.8336 0.3440 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8903 13.6583 0.3175 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5246 15.9925 0.1253 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1172 13.6052 0.2610 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8843 15.2238 0.2084 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4082 12.7919 0.4113 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8371 13.6060 0.3857 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2520 11.2924 0.5791 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8814 10.3932 0.6186 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4270 11.1491 0.5336 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1882 12.8428 0.4686 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9232 18.4745 0.1261 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1220 19.8603 -0.7250 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1276 17.9335 1.0978 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5206 18.7709 1.2098 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7185 20.1474 0.3565 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5194 20.6934 -0.6080 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7700 22.4259 -1.6710 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.5122 17.6293 0.0105 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5010 7.9659 0.8167 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9634 8.7509 0.7353 N 0 0 3 0 0 0 0 0 0 0 0 0 8.2599 6.1810 0.9378 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8659 5.3613 1.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2598 2.5547 0.1695 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7660 1.1225 0.6734 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8065 1.3527 1.9961 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6348 3.6521 1.1389 N 0 0 3 0 0 0 0 0 0 0 0 0 8.7271 2.8686 2.2762 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 15.7854 0.0903 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4715 11.5624 0.4322 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8363 14.8770 0.2963 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3851 10.7134 0.6443 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3413 10.4829 0.5618 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1865 20.2866 -1.4777 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9741 16.8591 1.7655 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4567 18.3504 1.9652 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8088 20.8003 0.4469 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5242 18.1843 -0.1497 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1771 8.2362 -0.2434 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1411 8.3832 1.8513 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0021 8.1305 0.7623 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5838 5.9109 1.9979 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6198 5.7639 -0.0966 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5418 5.6315 -0.0372 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5058 5.7785 2.0574 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0220 2.7787 -0.8268 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0609 0.0000 0.1474 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2304 0.4372 2.6697 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 30 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 31 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 32 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 33 1 0 0 0 0 10 11 1 0 0 0 0 10 22 1 0 0 0 0 11 34 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 35 1 0 0 0 0 15 16 2 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 17 18 2 0 0 0 0 17 38 1 0 0 0 0 18 19 1 0 0 0 0 20 39 1 0 0 0 0 21 22 1 0 0 0 0 21 23 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 28 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 28 1 0 0 0 0 25 26 2 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 27 29 2 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 M END > (483) 482 > (483) C21H20ClN7 > (483) 405.8889 > (483) FGFR-P482 > (483) Pyrazine-Pyridine Biheteroaryl 57 > (483) FGFR-2 Tyrosine Kinase > (483) 326 > (483) BINDDB > (483) <2007 > (483) P > (483) TRAIN $$$$ Pyrazine-Pyridine Biheteroaryl 58 csChFnd70/04170815452D 48 51 0 0 0 0 0 0 0 0999 V2000 1.1077 14.7583 0.1526 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4685 12.4329 0.3440 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8903 13.2576 0.3175 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5246 15.5918 0.1253 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1172 13.2045 0.2610 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8843 14.8232 0.2084 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4082 12.3912 0.4113 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8371 13.2053 0.3857 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2520 10.8917 0.5791 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8814 9.9926 0.6186 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4270 10.7485 0.5336 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1882 12.4421 0.4686 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9232 18.0738 0.1261 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1220 19.4596 -0.7250 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1276 17.5329 1.0978 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5206 18.3702 1.2098 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7185 19.7467 0.3565 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5194 20.2927 -0.6080 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7700 22.0253 -1.6710 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.5122 17.2286 0.0105 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5010 7.5652 0.8167 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9634 8.3503 0.7353 N 0 0 3 0 0 0 0 0 0 0 0 0 8.2599 5.7804 0.9378 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8659 4.9605 1.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2473 2.1426 0.1845 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8444 0.9431 1.9433 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6348 3.2515 1.1389 N 0 0 3 0 0 0 0 0 0 0 0 0 8.7302 2.4461 2.2695 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7634 0.7633 0.6806 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 15.3848 0.0903 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4715 11.1618 0.4322 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8363 14.4764 0.2963 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3851 10.3128 0.6443 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3413 10.0822 0.5618 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1865 19.8859 -1.4777 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9741 16.4584 1.7655 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4567 17.9497 1.9652 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8088 20.3996 0.4469 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5242 17.7836 -0.1497 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1771 7.8355 -0.2434 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1411 7.9825 1.8513 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0021 7.7298 0.7623 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5838 5.5102 1.9979 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6198 5.3632 -0.0966 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5418 5.2307 -0.0372 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5058 5.3777 2.0574 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0024 2.3539 -0.8199 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2847 0.0000 2.5921 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 30 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 31 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 32 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 33 1 0 0 0 0 10 11 1 0 0 0 0 10 22 1 0 0 0 0 11 34 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 35 1 0 0 0 0 15 16 2 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 17 18 2 0 0 0 0 17 38 1 0 0 0 0 18 19 1 0 0 0 0 20 39 1 0 0 0 0 21 22 1 0 0 0 0 21 23 1 0 0 0 0 21 40 1 0 0 0 0 21 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 27 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 27 1 0 0 0 0 25 29 2 0 0 0 0 25 47 1 0 0 0 0 26 28 2 0 0 0 0 26 29 1 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 M END > (484) 483 > (484) C20H19ClN8 > (484) 406.8767 > (484) FGFR-P483 > (484) Pyrazine-Pyridine Biheteroaryl 58 > (484) FGFR-2 Tyrosine Kinase > (484) 153 > (484) BINDDB > (484) <2007 > (484) P > (484) TRAIN $$$$ Pyrazine-Pyridine Biheteroaryl 7 csChFnd70/04170815452D 43 45 0 0 0 0 0 0 0 0999 V2000 0.9994 10.8825 0.1376 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2273 8.7844 0.3104 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5101 9.5286 0.2865 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2779 11.6346 0.1130 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0080 9.4807 0.2355 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5047 10.9410 0.1880 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8797 8.7468 0.3711 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1689 9.4814 0.3480 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4455 7.3939 0.5224 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2088 6.5826 0.5581 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8967 7.2647 0.4815 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3879 8.7927 0.4228 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5398 13.8740 0.1138 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7192 15.1244 -0.6541 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6264 13.3859 0.9905 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8833 14.1414 1.0915 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0618 15.3834 0.3217 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9800 15.8761 -0.5485 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2061 17.4394 -1.5077 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.2667 13.1114 0.0095 N 0 0 3 0 0 0 0 0 0 0 0 0 6.2828 5.1008 0.6634 N 0 0 3 0 0 0 0 0 0 0 0 0 7.6702 4.3925 0.7368 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4526 2.7820 0.8462 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9016 2.0424 0.9229 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6983 0.5382 1.0250 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.4477 0.0814 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2300 7.6375 0.3899 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1681 10.6282 0.2673 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4678 6.8715 0.5813 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9171 6.6634 0.5069 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8751 15.5090 -1.3333 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4880 12.4165 1.5930 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7278 13.7620 1.7732 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0457 15.9725 0.4032 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3752 13.6121 -0.1351 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4154 4.5410 0.6878 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2802 4.6364 -0.2196 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2477 4.7690 1.6704 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8427 2.5383 1.8027 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8752 2.4056 -0.0872 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5115 2.2862 -0.0335 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4791 2.4188 1.8563 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5742 0.0000 1.0778 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 26 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 27 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 28 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 29 1 0 0 0 0 10 11 1 0 0 0 0 10 21 1 0 0 0 0 11 30 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 31 1 0 0 0 0 15 16 2 0 0 0 0 15 32 1 0 0 0 0 16 17 1 0 0 0 0 16 33 1 0 0 0 0 17 18 2 0 0 0 0 17 34 1 0 0 0 0 18 19 1 0 0 0 0 20 35 1 0 0 0 0 21 22 1 0 0 0 0 21 36 1 0 0 0 0 22 23 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 24 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 24 25 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 43 1 0 0 0 0 M END > (485) 484 > (485) C18H18ClN5O > (485) 355.8261 > (485) FGFR-P484 > (485) Pyrazine-Pyridine Biheteroaryl 7 > (485) FGFR-2 Tyrosine Kinase > (485) 210 > (485) BINDDB > (485) <2007 > (485) P > (485) TRAIN $$$$ 1,6-naphthyridin 35 csChFnd70/04170815452D 56 58 0 0 0 0 0 0 0 0999 V2000 1.1422 15.4389 0.5800 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3665 12.6682 0.3628 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0236 13.3205 0.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7712 16.2256 0.2652 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2598 15.1432 -0.0121 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9702 18.0571 0.2162 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0442 17.5674 -0.3670 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6250 18.7262 -0.1035 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0026 13.7243 0.6164 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8291 15.8561 -0.3156 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9063 20.6467 -0.1694 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5960 23.3535 1.2816 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3349 21.5642 1.3519 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7510 21.5429 -1.7545 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0153 23.3324 -1.8074 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4333 24.2356 -0.2931 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1170 10.8650 0.4205 N 0 0 3 0 0 0 0 0 0 0 0 0 3.6024 9.6814 0.1445 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9763 7.7817 0.2747 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2271 20.4117 -3.6568 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.5391 20.4596 3.3295 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.6951 18.2449 -0.6858 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5275 6.5455 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9015 4.6459 0.1166 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3909 3.4591 -0.1602 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6731 3.6172 1.2662 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4002 2.7657 0.7096 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7958 1.6391 -0.3541 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0105 1.3839 -2.1806 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.2447 0.7989 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1165 12.4451 -0.1596 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8643 18.9156 0.4212 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9280 24.0653 2.4584 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8959 24.0278 -3.0338 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6388 25.6346 -0.3412 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9594 10.3904 0.6438 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1600 9.9112 -1.1499 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5963 9.9243 1.1408 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4187 7.5519 1.5691 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9826 7.5387 -0.7216 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6789 17.4614 -0.8687 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8687 19.5031 -0.7266 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0852 6.7753 -1.3080 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5214 6.7885 0.9827 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3439 4.4161 1.4110 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9078 4.4029 -0.8797 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8949 4.9977 1.5560 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1725 2.9607 2.4313 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1664 1.4021 0.3556 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9348 3.4645 -0.4152 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3302 2.8237 1.7918 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9047 0.7553 -0.1850 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8052 1.3544 0.6341 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9428 1.8300 -3.1662 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7254 0.0000 -2.3869 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8040 2.1399 -2.2898 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 30 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 31 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 32 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 22 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 33 1 0 0 0 0 13 21 1 0 0 0 0 14 15 1 0 0 0 0 14 20 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 35 1 0 0 0 0 17 18 1 0 0 0 0 17 36 1 0 0 0 0 18 19 1 0 0 0 0 18 37 1 0 0 0 0 18 38 1 0 0 0 0 19 23 1 0 0 0 0 19 39 1 0 0 0 0 19 40 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 28 1 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 29 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 29 56 1 0 0 0 0 M END > (50) 48 > (50) C22H27Cl2N5 > (50) 432.3948 > (50) FGFR-P48 > (50) 1,6-naphthyridine 35 > (50) FGFR-1 Tyrosine Kinase > (50) 350 > (50) BINDDB > (50) <2007 > (50) P > (50) TRAIN $$$$ 1,6-naphthyridin 36 csChFnd70/04170815452D 66 68 0 0 0 0 0 0 0 0999 V2000 1.1158 15.2141 -2.4536 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2011 12.3956 -1.8570 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9203 12.9968 -1.6412 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8145 15.9514 -2.2611 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2639 14.8179 -1.8429 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1213 17.7817 -2.4713 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2134 17.1917 -1.8431 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8404 18.3994 -2.2584 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8768 13.4984 -2.2487 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8975 15.4830 -1.6519 N 0 0 0 0 0 0 0 0 0 0 0 0 5.2368 20.3167 -2.4661 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5209 23.2335 -1.2041 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1494 21.4485 -1.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7060 20.9952 -4.1249 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0744 22.7828 -4.3094 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9793 23.8994 -2.8538 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8453 10.5946 -1.6611 N 0 0 3 0 0 0 0 0 0 0 0 0 3.2858 9.3598 -1.2300 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5421 7.4739 -1.0901 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8276 19.5958 -5.9531 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.5744 20.6156 1.0693 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.0464 6.1844 -0.6400 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3027 4.2984 -0.5000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7471 3.0603 -0.0679 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0445 1.2976 0.3859 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2640 1.3419 2.2615 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0312 2.9453 -1.5320 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7393 2.0683 -0.8676 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9340 17.8202 -1.6315 N 0 0 3 0 0 0 0 0 0 0 0 0 9.2594 16.6842 -1.2349 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9482 15.1095 -1.0623 O 0 0 0 0 0 0 0 0 0 0 0 0 10.9295 17.2943 -1.0296 N 0 0 3 0 0 0 0 0 0 0 0 0 12.3701 16.0595 -0.5984 C 0 0 0 0 0 0 0 0 0 0 0 0 14.1169 17.0854 -0.4397 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.0596 -2.7655 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9797 12.0838 -1.3230 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0482 18.6787 -2.7896 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4538 24.1113 -0.0717 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4379 23.3098 -5.5930 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2684 25.2959 -3.0051 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6433 10.1555 -1.8098 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2895 9.4065 -2.2721 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8834 9.7376 0.0331 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5383 7.4271 -0.0481 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9443 7.0960 -2.3532 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0502 6.2311 -1.6820 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6441 6.5622 0.6231 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2989 4.2517 0.5420 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7050 3.9206 -1.7631 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0102 0.9325 -0.5587 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1138 0.3232 0.3311 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0878 2.1855 2.2749 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9000 0.0000 2.6644 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2482 1.8716 3.1814 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4688 2.1543 -2.6061 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3294 4.2760 -2.0179 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3379 2.8940 0.1598 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4308 0.7643 -0.3198 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6667 1.9215 -1.9696 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1825 19.0768 -1.7693 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1779 18.5509 -1.1672 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0814 15.4011 0.6579 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4862 15.0685 -1.6472 H 0 0 0 0 0 0 0 0 0 0 0 0 14.4056 17.7441 -1.6960 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0007 18.0767 0.6090 H 0 0 0 0 0 0 0 0 0 0 0 0 15.1886 16.1668 -0.1190 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 35 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 36 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 37 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 29 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 38 1 0 0 0 0 13 21 1 0 0 0 0 14 15 1 0 0 0 0 14 20 1 0 0 0 0 15 16 2 0 0 0 0 15 39 1 0 0 0 0 16 40 1 0 0 0 0 17 18 1 0 0 0 0 17 41 1 0 0 0 0 18 19 1 0 0 0 0 18 42 1 0 0 0 0 18 43 1 0 0 0 0 19 22 1 0 0 0 0 19 44 1 0 0 0 0 19 45 1 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 23 24 1 0 0 0 0 23 48 1 0 0 0 0 23 49 1 0 0 0 0 24 27 1 0 0 0 0 24 25 1 0 0 0 0 25 26 1 0 0 0 0 25 50 1 0 0 0 0 25 51 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 26 54 1 0 0 0 0 27 28 1 0 0 0 0 27 55 1 0 0 0 0 27 56 1 0 0 0 0 28 57 1 0 0 0 0 28 58 1 0 0 0 0 28 59 1 0 0 0 0 29 30 1 0 0 0 0 29 60 1 0 0 0 0 30 31 2 0 0 0 0 30 32 1 0 0 0 0 32 33 1 0 0 0 0 32 61 1 0 0 0 0 33 34 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 34 64 1 0 0 0 0 34 65 1 0 0 0 0 34 66 1 0 0 0 0 M END > (51) 49 > (51) C25H32Cl2N6O > (51) 503.4734 > (51) FGFR-P49 > (51) 1,6-naphthyridine 36 > (51) FGFR-1 Tyrosine Kinase > (51) 29 > (51) BINDDB > (51) <2007 > (51) P > (51) TRAIN $$$$ 1,6-naphthyridin 37 csChFnd70/04170815452D 72 74 0 0 0 0 0 0 0 0999 V2000 1.1348 15.3372 0.5765 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3511 12.5847 0.3606 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9975 13.2324 0.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7536 16.1189 0.2638 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2324 15.0433 -0.0117 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9516 17.9378 0.2150 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0051 17.4506 -0.3643 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5968 18.6018 -0.1027 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9963 13.6339 0.6127 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7913 15.7515 -0.3131 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8774 20.5097 -0.1683 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5642 23.1983 1.2731 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3038 21.4210 1.3430 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7234 21.4000 -1.7430 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9871 23.1776 -1.7957 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4035 24.0746 -0.2914 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1030 10.7932 0.4175 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5787 9.6173 0.1432 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9562 7.7301 0.2717 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2022 20.2762 -3.6327 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.5060 20.3235 3.3076 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.4973 6.5019 -0.0147 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8749 4.6148 0.1137 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3545 3.4354 -0.1613 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6281 3.5918 1.2561 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3439 2.7458 0.7032 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7633 1.6276 -0.3545 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9832 1.3747 -2.1692 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6512 18.1253 -0.6822 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0088 17.0437 -0.9345 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7921 15.4770 -0.8838 O 0 0 0 0 0 0 0 0 0 0 0 0 10.6066 17.6986 -1.2433 N 0 0 3 0 0 0 0 0 0 0 0 0 11.7236 15.3648 -3.0974 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7318 17.5912 -1.8384 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0823 16.5226 -1.5175 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3327 15.3841 0.0970 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.1378 0.7942 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0833 12.3625 -0.1579 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8534 18.7912 0.4188 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8944 23.9055 2.4420 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8683 23.8686 -3.0141 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6084 25.4645 -0.3393 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9528 10.3220 0.6388 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1329 9.8459 -1.1427 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5658 9.8581 1.1333 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4020 7.5014 1.5576 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9691 7.4892 -0.7183 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0515 6.7305 -1.3005 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4844 6.7428 0.9753 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3208 4.3860 1.3996 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8879 4.3738 -0.8763 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8486 4.9634 1.5445 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1303 2.9394 2.4133 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1115 1.3914 0.3510 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8753 3.4404 -0.4139 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2674 2.8029 1.7787 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8644 0.7491 -0.1866 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7786 1.3445 0.6268 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6997 0.0000 -2.3749 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7848 2.1261 -2.2778 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9096 1.8180 -3.1482 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8240 19.3753 -0.7227 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7795 18.9486 -1.2837 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5453 16.1759 -4.2474 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8215 14.4899 -3.3015 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5486 14.6035 -2.8688 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9872 18.4162 -0.7129 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8297 16.7163 -2.0425 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5533 18.4024 -2.9886 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1577 14.6227 0.3255 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4307 14.5091 -0.1071 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5882 16.2089 1.2224 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 37 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 5 2 0 0 0 0 3 38 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 39 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 29 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 40 1 0 0 0 0 13 21 1 0 0 0 0 14 15 1 0 0 0 0 14 20 1 0 0 0 0 15 16 2 0 0 0 0 15 41 1 0 0 0 0 16 42 1 0 0 0 0 17 18 1 0 0 0 0 17 43 1 0 0 0 0 18 19 1 0 0 0 0 18 44 1 0 0 0 0 18 45 1 0 0 0 0 19 22 1 0 0 0 0 19 46 1 0 0 0 0 19 47 1 0 0 0 0 22 23 1 0 0 0 0 22 48 1 0 0 0 0 22 49 1 0 0 0 0 23 24 1 0 0 0 0 23 50 1 0 0 0 0 23 51 1 0 0 0 0 24 27 1 0 0 0 0 24 25 1 0 0 0 0 25 26 1 0 0 0 0 25 52 1 0 0 0 0 25 53 1 0 0 0 0 26 54 1 0 0 0 0 26 55 1 0 0 0 0 26 56 1 0 0 0 0 27 28 1 0 0 0 0 27 57 1 0 0 0 0 27 58 1 0 0 0 0 28 59 1 0 0 0 0 28 60 1 0 0 0 0 28 61 1 0 0 0 0 29 30 1 0 0 0 0 29 62 1 0 0 0 0 30 31 2 0 0 0 0 30 32 1 0 0 0 0 32 35 1 0 0 0 0 32 63 1 0 0 0 0 33 35 1 0 0 0 0 33 64 1 0 0 0 0 33 65 1 0 0 0 0 33 66 1 0 0 0 0 34 35 1 0 0 0 0 34 67 1 0 0 0 0 34 68 1 0 0 0 0 34 69 1 0 0 0 0 35 36 1 0 0 0 0 36 70 1 0 0 0 0 36 71 1 0 0 0 0 36 72 1 0 0 0 0 M END > (52) 50 > (52) C27H36Cl2N6O > (52) 531.527 > (52) FGFR-P50 > (52) 1,6-naphthyridine 37 > (52) FGFR-1 Tyrosine Kinase > (52) 25 > (52) BINDDB > (52) <2007 > (52) P > (52) TRAIN $$$$ Pyrido[2,3-d]pyrimidine 102 csChFnd70/04170815452D 73 76 0 0 0 0 0 0 0 0999 V2000 3.9903 16.0163 0.0121 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5035 13.4206 -0.0164 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5846 16.9099 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1493 15.9288 -0.0186 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6685 18.7350 0.0100 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7971 18.4475 -0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2976 19.5061 -0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0136 14.3022 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6850 16.7375 -0.0295 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4640 21.4277 0.0047 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6841 24.2198 -1.1732 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5255 22.4246 -1.1829 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5534 22.2409 1.2035 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7058 24.0366 1.2062 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7751 25.0248 0.0176 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4256 19.2249 -0.0338 N 0 0 3 0 0 0 0 0 0 0 0 0 11.8706 18.2324 -0.0529 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7469 16.6558 -0.0597 O 0 0 0 0 0 0 0 0 0 0 0 0 13.4526 18.9875 -0.0646 N 0 0 3 0 0 0 0 0 0 0 0 0 16.6324 19.0799 -0.0951 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0233 17.9088 -0.0853 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7698 25.1932 -2.3315 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9953 27.0364 -2.2485 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7680 24.8306 2.3750 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8632 26.6857 2.3045 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4416 11.6241 -0.0254 N 0 0 3 0 0 0 0 0 0 0 0 0 3.7594 10.7286 -0.0142 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0556 8.7606 -0.0276 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2989 7.8253 -0.0157 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0373 14.1911 -0.0268 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8941 5.4492 -1.3319 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2273 3.4889 -1.2330 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2774 3.0382 -0.2291 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9443 4.9984 -0.3279 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5831 5.9358 -0.0286 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5883 2.5516 -1.5323 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8726 0.6620 -1.5452 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7735 16.7183 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4991 19.5135 0.0248 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6761 21.7987 -2.1102 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2776 21.4722 2.1298 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8963 26.4244 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5241 20.4827 -0.0285 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5513 20.2454 -0.0592 H 0 0 0 0 0 0 0 0 0 0 0 0 16.6099 19.9041 -1.2485 H 0 0 0 0 0 0 0 0 0 0 0 0 16.6326 19.8924 1.0668 H 0 0 0 0 0 0 0 0 0 0 0 0 17.8011 18.2771 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0458 17.0843 1.0680 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0231 17.0960 -1.2472 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1939 27.6556 -3.2408 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6058 27.5029 -0.9677 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3581 27.3563 -2.4740 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5747 27.2338 2.5270 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7540 27.1515 3.3043 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3335 27.0866 1.0286 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5118 10.9560 -0.0392 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0392 11.0902 1.1524 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0171 11.1027 -1.1628 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7756 8.3990 -1.1941 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7977 8.3864 1.1212 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5786 8.1870 1.1508 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5565 8.1994 -1.1645 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1004 6.1476 -1.0730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4215 5.7840 -2.6262 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1714 3.1190 -2.2239 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7332 3.1592 0.0497 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7498 2.7034 1.0651 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0709 2.3399 -0.4880 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4382 5.3282 -1.6107 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.3685 0.6628 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4070 0.2560 -0.2963 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6390 0.0000 -1.7692 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7827 0.3280 -2.5798 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 38 1 0 0 0 0 2 8 2 0 0 0 0 2 30 1 0 0 0 0 2 26 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 30 2 0 0 0 0 4 9 1 0 0 0 0 5 7 2 0 0 0 0 5 39 1 0 0 0 0 6 9 2 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 10 1 0 0 0 0 10 12 1 0 0 0 0 10 13 2 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 11 22 1 0 0 0 0 12 40 1 0 0 0 0 13 14 1 0 0 0 0 13 41 1 0 0 0 0 14 15 2 0 0 0 0 14 24 1 0 0 0 0 15 42 1 0 0 0 0 16 17 1 0 0 0 0 16 43 1 0 0 0 0 17 18 2 0 0 0 0 17 19 1 0 0 0 0 19 21 1 0 0 0 0 19 44 1 0 0 0 0 20 21 1 0 0 0 0 20 45 1 0 0 0 0 20 46 1 0 0 0 0 20 47 1 0 0 0 0 21 48 1 0 0 0 0 21 49 1 0 0 0 0 22 23 1 0 0 0 0 23 50 1 0 0 0 0 23 51 1 0 0 0 0 23 52 1 0 0 0 0 24 25 1 0 0 0 0 25 53 1 0 0 0 0 25 54 1 0 0 0 0 25 55 1 0 0 0 0 26 27 1 0 0 0 0 26 56 1 0 0 0 0 27 28 1 0 0 0 0 27 57 1 0 0 0 0 27 58 1 0 0 0 0 28 29 1 0 0 0 0 28 59 1 0 0 0 0 28 60 1 0 0 0 0 29 35 1 0 0 0 0 29 61 1 0 0 0 0 29 62 1 0 0 0 0 31 35 1 0 0 0 0 31 32 1 0 0 0 0 31 63 1 0 0 0 0 31 64 1 0 0 0 0 32 36 1 0 0 0 0 32 65 1 0 0 0 0 32 66 1 0 0 0 0 33 36 1 0 0 0 0 33 34 1 0 0 0 0 33 67 1 0 0 0 0 33 68 1 0 0 0 0 34 35 1 0 0 0 0 34 69 1 0 0 0 0 34 70 1 0 0 0 0 36 37 1 0 0 0 0 37 71 1 0 0 0 0 37 72 1 0 0 0 0 37 73 1 0 0 0 0 M END > (514) 513 > (514) C26H36N8O3 > (514) 508.6222 > (514) FGFR-P513 > (514) Pyrido[2,3-d]pyrimidine 102 > (514) FGFR-1 Tyrosine Kinase > (514) 33 > (514) BINDDB > (514) <2007 > (514) P > (514) TRAIN $$$$ Pyrido[2,3-d]pyrimidine 103 csChFnd70/04170815452D 79 82 0 0 0 0 0 0 0 0999 V2000 3.9894 16.0130 0.0121 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5022 13.4177 -0.0164 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5834 16.9063 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1477 15.9255 -0.0186 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6673 18.7309 0.0100 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7952 18.4435 -0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2960 19.5019 -0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0127 14.2992 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6831 16.7340 -0.0295 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4623 21.4231 0.0047 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6827 24.2146 -1.1729 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5241 22.4198 -1.1827 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5515 22.2361 1.2032 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7039 24.0314 1.2060 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7734 25.0195 0.0176 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4233 19.2207 -0.0338 N 0 0 3 0 0 0 0 0 0 0 0 0 11.8680 18.2285 -0.0529 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7444 16.6523 -0.0597 O 0 0 0 0 0 0 0 0 0 0 0 0 13.4497 18.9835 -0.0646 N 0 0 3 0 0 0 0 0 0 0 0 0 15.0199 16.7644 -1.7159 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7686 25.1878 -2.3310 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9939 27.0306 -2.2480 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7659 24.8254 2.3746 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8611 26.6800 2.3041 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4404 11.6216 -0.0254 N 0 0 3 0 0 0 0 0 0 0 0 0 3.7587 10.7263 -0.0142 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0547 8.7587 -0.0276 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2984 7.8236 -0.0157 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0358 14.1881 -0.0268 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8933 5.4481 -1.3316 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2264 3.4882 -1.2327 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2771 3.0376 -0.2290 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9440 4.9973 -0.3279 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5826 5.9345 -0.0286 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5878 2.5511 -1.5320 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8720 0.6620 -1.5449 C 0 0 0 0 0 0 0 0 0 0 0 0 16.6289 19.0757 -0.0951 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0201 17.9050 -0.0853 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0515 16.7480 1.5333 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7729 16.7147 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4982 19.5093 0.0248 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6749 21.7940 -2.1098 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2756 21.4676 2.1294 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8946 26.4189 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5219 20.4783 -0.0285 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5484 20.2411 -0.0592 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9974 17.5886 -2.8689 H 0 0 0 0 0 0 0 0 0 0 0 0 16.1883 15.9619 -1.7312 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8738 15.9303 -1.7089 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1928 27.6498 -3.2402 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6045 27.4971 -0.9674 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3565 27.3505 -2.4734 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 27.0808 1.0283 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5728 27.2280 2.5265 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7517 27.1457 3.3037 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5103 10.9536 -0.0391 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0386 11.0879 1.1521 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0165 11.1003 -1.1625 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7747 8.3971 -1.1939 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7968 8.3846 1.1209 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5783 8.1853 1.1506 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5562 8.1976 -1.1642 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0994 6.1463 -1.0728 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4208 5.7827 -2.6256 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1703 3.1183 -2.2235 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7323 3.1585 0.0497 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7494 2.7028 1.0649 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0709 2.3393 -0.4879 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4381 5.3270 -1.6104 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.3673 0.6627 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4063 0.2559 -0.2963 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6386 0.0000 -1.7688 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7820 0.3280 -2.5793 H 0 0 0 0 0 0 0 0 0 0 0 0 16.6290 19.8881 1.0665 H 0 0 0 0 0 0 0 0 0 0 0 0 17.7972 18.2732 -0.1105 H 0 0 0 0 0 0 0 0 0 0 0 0 16.6064 19.8998 -1.2482 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9054 15.9139 1.5402 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2199 15.9455 1.5178 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0516 17.5605 2.6949 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 40 1 0 0 0 0 2 8 2 0 0 0 0 2 29 1 0 0 0 0 2 25 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 29 2 0 0 0 0 4 9 1 0 0 0 0 5 7 2 0 0 0 0 5 41 1 0 0 0 0 6 9 2 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 10 1 0 0 0 0 10 12 1 0 0 0 0 10 13 2 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 11 21 1 0 0 0 0 12 42 1 0 0 0 0 13 14 1 0 0 0 0 13 43 1 0 0 0 0 14 15 2 0 0 0 0 14 23 1 0 0 0 0 15 44 1 0 0 0 0 16 17 1 0 0 0 0 16 45 1 0 0 0 0 17 18 2 0 0 0 0 17 19 1 0 0 0 0 19 38 1 0 0 0 0 19 46 1 0 0 0 0 20 38 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 21 22 1 0 0 0 0 22 50 1 0 0 0 0 22 51 1 0 0 0 0 22 52 1 0 0 0 0 23 24 1 0 0 0 0 24 53 1 0 0 0 0 24 54 1 0 0 0 0 24 55 1 0 0 0 0 25 26 1 0 0 0 0 25 56 1 0 0 0 0 26 27 1 0 0 0 0 26 57 1 0 0 0 0 26 58 1 0 0 0 0 27 28 1 0 0 0 0 27 59 1 0 0 0 0 27 60 1 0 0 0 0 28 34 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 30 34 1 0 0 0 0 30 31 1 0 0 0 0 30 63 1 0 0 0 0 30 64 1 0 0 0 0 31 35 1 0 0 0 0 31 65 1 0 0 0 0 31 66 1 0 0 0 0 32 35 1 0 0 0 0 32 33 1 0 0 0 0 32 67 1 0 0 0 0 32 68 1 0 0 0 0 33 34 1 0 0 0 0 33 69 1 0 0 0 0 33 70 1 0 0 0 0 35 36 1 0 0 0 0 36 71 1 0 0 0 0 36 72 1 0 0 0 0 36 73 1 0 0 0 0 37 38 1 0 0 0 0 37 74 1 0 0 0 0 37 75 1 0 0 0 0 37 76 1 0 0 0 0 38 39 1 0 0 0 0 39 77 1 0 0 0 0 39 78 1 0 0 0 0 39 79 1 0 0 0 0 M END > (515) 514 > (515) C28H40N8O3 > (515) 536.6758 > (515) FGFR-P514 > (515) Pyrido[2,3-d]pyrimidine 103 > (515) FGFR-1 Tyrosine Kinase > (515) 19 > (515) BINDDB > (515) <2007 > (515) P > (515) TRAIN $$$$ Pyrido[2,3-d]pyrimidine 104 csChFnd70/04170815452D 73 75 0 0 0 0 0 0 0 0999 V2000 5.9041 14.8061 0.0102 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6172 12.3882 -0.3875 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3732 15.8492 -0.2356 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9871 15.0347 -0.5656 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2858 17.6638 -0.1643 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3576 17.6913 -0.7446 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8001 18.5892 -0.4227 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0854 13.1123 -0.0757 N 0 0 0 0 0 0 0 0 0 0 0 0 10.4069 15.9880 -0.8055 N 0 0 0 0 0 0 0 0 0 0 0 0 8.7837 20.5075 -0.3632 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5560 23.2233 -1.2640 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5678 21.4311 -1.3226 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9795 21.3901 0.6583 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9608 23.1824 0.7111 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7529 24.0983 -0.2511 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8706 18.6230 -1.0028 N 0 0 3 0 0 0 0 0 0 0 0 0 13.3691 17.7850 -1.3116 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3947 16.2127 -1.3640 O 0 0 0 0 0 0 0 0 0 0 0 0 14.8390 18.6902 -1.5624 N 0 0 3 0 0 0 0 0 0 0 0 0 17.9255 19.0987 -2.1341 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3709 24.1252 -2.2000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4328 25.9697 -2.0791 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1267 24.0442 1.7069 O 0 0 0 0 0 0 0 0 0 0 0 0 11.0337 25.8914 1.7004 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7233 10.6044 -0.4621 N 0 0 3 0 0 0 0 0 0 0 0 0 6.1691 9.5506 -0.2005 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6394 7.6325 -0.3480 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0162 6.5319 -0.0747 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0390 13.3040 -0.6283 N 0 0 0 0 0 0 0 0 0 0 0 0 16.4677 17.7793 -1.8982 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4866 4.6140 -0.2222 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9280 3.5570 0.0401 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6778 3.8258 -1.3670 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9110 3.1146 -0.8249 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3738 1.7170 0.2134 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1270 1.3870 2.0148 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6558 15.3791 0.2696 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0755 18.3174 0.0841 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6357 20.7507 -2.1115 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9198 20.6778 1.4084 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7410 25.4953 -0.2077 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8500 19.8776 -0.9610 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8184 19.9448 -1.5206 H 0 0 0 0 0 0 0 0 0 0 0 0 18.0527 19.8734 -0.9620 H 0 0 0 0 0 0 0 0 0 0 0 0 19.1371 18.4210 -2.3841 H 0 0 0 0 0 0 0 0 0 0 0 0 17.6247 19.9418 -3.2246 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4200 26.5282 -2.8869 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2335 26.3601 -0.7382 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6921 26.4278 -2.5200 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2314 26.3676 0.3873 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7648 26.3000 2.1626 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0336 26.4156 2.5464 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8270 10.0501 -0.6877 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6371 9.8070 1.0807 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2094 9.8761 -1.1818 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1714 7.3762 -1.6292 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5991 7.3068 0.6335 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4843 6.7884 1.2065 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0564 6.8575 -1.0562 H 0 0 0 0 0 0 0 0 0 0 0 0 16.7685 16.9362 -0.8078 H 0 0 0 0 0 0 0 0 0 0 0 0 16.3402 17.0047 -3.0705 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0185 4.3575 -1.5035 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4463 4.2884 0.7591 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5659 5.2053 -1.6396 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1207 3.1519 -2.5246 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4379 3.8330 0.2934 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.2540 -1.8929 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0361 1.7502 -0.4886 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2135 0.9335 0.0381 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3279 1.3700 -0.7661 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3734 2.0377 2.1297 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2429 1.8885 2.9932 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3012 0.0000 2.2049 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 37 1 0 0 0 0 2 8 2 0 0 0 0 2 29 1 0 0 0 0 2 25 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 29 2 0 0 0 0 4 9 1 0 0 0 0 5 7 2 0 0 0 0 5 38 1 0 0 0 0 6 9 2 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 10 1 0 0 0 0 10 12 1 0 0 0 0 10 13 2 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 11 21 1 0 0 0 0 12 39 1 0 0 0 0 13 14 1 0 0 0 0 13 40 1 0 0 0 0 14 15 2 0 0 0 0 14 23 1 0 0 0 0 15 41 1 0 0 0 0 16 17 1 0 0 0 0 16 42 1 0 0 0 0 17 18 2 0 0 0 0 17 19 1 0 0 0 0 19 30 1 0 0 0 0 19 43 1 0 0 0 0 20 30 1 0 0 0 0 20 44 1 0 0 0 0 20 45 1 0 0 0 0 20 46 1 0 0 0 0 21 22 1 0 0 0 0 22 47 1 0 0 0 0 22 48 1 0 0 0 0 22 49 1 0 0 0 0 23 24 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 24 52 1 0 0 0 0 25 26 1 0 0 0 0 25 53 1 0 0 0 0 26 27 1 0 0 0 0 26 54 1 0 0 0 0 26 55 1 0 0 0 0 27 28 1 0 0 0 0 27 56 1 0 0 0 0 27 57 1 0 0 0 0 28 31 1 0 0 0 0 28 58 1 0 0 0 0 28 59 1 0 0 0 0 30 60 1 0 0 0 0 30 61 1 0 0 0 0 31 32 1 0 0 0 0 31 62 1 0 0 0 0 31 63 1 0 0 0 0 32 35 1 0 0 0 0 32 33 1 0 0 0 0 33 34 1 0 0 0 0 33 64 1 0 0 0 0 33 65 1 0 0 0 0 34 66 1 0 0 0 0 34 67 1 0 0 0 0 34 68 1 0 0 0 0 35 36 1 0 0 0 0 35 69 1 0 0 0 0 35 70 1 0 0 0 0 36 71 1 0 0 0 0 36 72 1 0 0 0 0 36 73 1 0 0 0 0 M END > (516) 515 > (516) C26H37N7O3 > (516) 495.6234 > (516) FGFR-P515 > (516) Pyrido[2,3-d]pyrimidine 104 > (516) FGFR-1 Tyrosine Kinase > (516) 35 > (516) BINDDB > (516) <2007 > (516) P > (516) TRAIN $$$$ Pyrido[2,3-d]pyrimidine 105 csChFnd70/04170815452D 63 65 0 0 0 0 0 0 0 0999 V2000 2.4664 10.6687 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9742 8.0820 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0551 11.5591 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6144 10.5814 -0.0185 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1387 13.3779 0.0100 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2565 13.0914 -0.0219 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7622 14.1463 -0.0019 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4896 8.9606 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1448 11.3873 -0.0294 N 0 0 0 0 0 0 0 0 0 0 0 0 5.9280 16.0612 0.0047 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1509 18.8436 -1.1691 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9928 17.0546 -1.1788 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0136 16.8715 1.1993 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1655 18.6609 1.2020 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2380 19.6458 0.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8793 13.8660 -0.0337 N 0 0 3 0 0 0 0 0 0 0 0 0 10.3192 12.8770 -0.0528 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1959 11.3059 -0.0595 O 0 0 0 0 0 0 0 0 0 0 0 0 11.8957 13.6296 -0.0644 N 0 0 3 0 0 0 0 0 0 0 0 0 13.4608 11.4177 -1.7103 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2397 19.8136 -2.3234 O 0 0 0 0 0 0 0 0 0 0 0 0 4.4644 21.6504 -2.2407 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2240 19.4523 2.3668 O 0 0 0 0 0 0 0 0 0 0 0 0 8.3189 21.3009 2.2966 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9125 6.2917 -0.0253 N 0 0 3 0 0 0 0 0 0 0 0 0 2.2364 5.3993 -0.0141 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5315 3.4381 -0.0275 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7809 2.5062 -0.0157 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5028 8.8499 -0.0267 N 0 0 0 0 0 0 0 0 0 0 0 0 15.0646 13.7215 -0.0948 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4610 12.5545 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4923 11.4013 1.5283 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0565 0.6746 -0.0283 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2539 11.3681 0.0331 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9735 14.1537 0.0248 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1463 16.4310 -2.1029 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7353 16.1055 2.1225 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3588 21.0406 0.0223 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9775 15.1195 -0.0284 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9941 14.8831 -0.0590 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4384 12.2392 -2.8595 H 0 0 0 0 0 0 0 0 0 0 0 0 14.6254 10.6177 -1.7256 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3184 10.5862 -1.7033 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6659 22.2675 -3.2296 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0763 22.1154 -0.9643 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8224 21.9692 -2.4654 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7875 21.7004 1.0250 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0348 21.8472 2.5182 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2065 21.7651 3.2928 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9791 5.6259 -0.0390 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5187 5.7597 1.1484 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4967 5.7722 -1.1587 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2490 3.0777 -1.1900 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2711 3.0653 1.1172 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0631 2.8666 1.1468 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0411 2.8790 -1.1604 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0647 14.5313 1.0631 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2290 12.9216 -0.1102 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0421 14.5429 -1.2442 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3499 10.5699 1.5351 H 0 0 0 0 0 0 0 0 0 0 0 0 14.6569 10.6014 1.5129 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4924 12.2111 2.6861 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.0000 -0.0218 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 34 1 0 0 0 0 2 8 2 0 0 0 0 2 29 1 0 0 0 0 2 25 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 29 2 0 0 0 0 4 9 1 0 0 0 0 5 7 2 0 0 0 0 5 35 1 0 0 0 0 6 9 2 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 10 1 0 0 0 0 10 12 1 0 0 0 0 10 13 2 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 11 21 1 0 0 0 0 12 36 1 0 0 0 0 13 14 1 0 0 0 0 13 37 1 0 0 0 0 14 15 2 0 0 0 0 14 23 1 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 16 39 1 0 0 0 0 17 18 2 0 0 0 0 17 19 1 0 0 0 0 19 31 1 0 0 0 0 19 40 1 0 0 0 0 20 31 1 0 0 0 0 20 41 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 22 1 0 0 0 0 22 44 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 24 47 1 0 0 0 0 24 48 1 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 25 50 1 0 0 0 0 26 27 1 0 0 0 0 26 51 1 0 0 0 0 26 52 1 0 0 0 0 27 28 1 0 0 0 0 27 53 1 0 0 0 0 27 54 1 0 0 0 0 28 33 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 30 31 1 0 0 0 0 30 57 1 0 0 0 0 30 58 1 0 0 0 0 30 59 1 0 0 0 0 31 32 1 0 0 0 0 32 60 1 0 0 0 0 32 61 1 0 0 0 0 32 62 1 0 0 0 0 33 63 1 0 0 0 0 M END > (517) 516 > (517) C23H30N6O4 > (517) 454.5278 > (517) FGFR-P516 > (517) Pyrido[2,3-d]pyrimidine 105 > (517) FGFR-1 Tyrosine Kinase > (517) 38 > (517) BINDDB > (517) <2007 > (517) P > (517) TRAIN $$$$ Pyrido[2,3-d]pyrimidine 12 csChFnd70/04170815452D 79 81 0 0 0 0 0 0 0 0999 V2000 5.9127 14.8277 0.0102 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6283 12.4064 -0.3881 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3840 15.8725 -0.2359 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0002 15.0566 -0.5664 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2964 17.6896 -0.1645 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3728 17.7172 -0.7457 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8130 18.6164 -0.4233 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0943 13.1314 -0.0758 N 0 0 0 0 0 0 0 0 0 0 0 0 10.4222 16.0114 -0.8066 N 0 0 0 0 0 0 0 0 0 0 0 0 8.7965 20.5375 -0.3637 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5670 23.2572 -1.2658 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5788 21.4624 -1.3246 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9942 21.4213 0.6592 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9754 23.2163 0.7121 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7656 24.1335 -0.2515 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8880 18.6503 -1.0043 N 0 0 3 0 0 0 0 0 0 0 0 0 13.3886 17.8110 -1.3135 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4143 16.2364 -1.3660 O 0 0 0 0 0 0 0 0 0 0 0 0 14.8607 18.7175 -1.5647 N 0 0 3 0 0 0 0 0 0 0 0 0 16.3126 16.7164 -3.5486 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3801 24.1604 -2.2032 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4422 26.0077 -2.0822 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1430 24.0793 1.7094 O 0 0 0 0 0 0 0 0 0 0 0 0 11.0498 25.9293 1.7029 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7346 10.6200 -0.4627 N 0 0 3 0 0 0 0 0 0 0 0 0 6.1781 9.5644 -0.2008 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6491 7.6436 -0.3485 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0234 6.5414 -0.0748 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0522 13.3234 -0.6292 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4946 4.6207 -0.2226 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9337 3.5623 0.0402 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6816 3.8313 -1.3690 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9122 3.1192 -0.8260 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3801 1.7195 0.2137 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1345 1.3891 2.0177 C 0 0 0 0 0 0 0 0 0 0 0 0 17.9516 19.1266 -2.1373 C 0 0 0 0 0 0 0 0 0 0 0 0 16.4918 17.8053 -1.9010 C 0 0 0 0 0 0 0 0 0 0 0 0 16.9146 16.6202 -0.3681 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6626 15.4016 0.2700 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0843 18.3442 0.0843 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6453 20.7810 -2.1146 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9357 20.7081 1.4105 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7538 25.5325 -0.2080 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8674 19.9066 -0.9624 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8401 19.9739 -1.5229 H 0 0 0 0 0 0 0 0 0 0 0 0 16.0114 17.5606 -4.6408 H 0 0 0 0 0 0 0 0 0 0 0 0 17.5262 16.0376 -3.7988 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2726 15.7750 -3.3804 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2426 26.3986 -0.7392 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7034 26.4665 -2.5236 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4280 26.5671 -2.8911 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2479 26.4061 0.3878 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7792 26.3385 2.1658 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0512 26.4543 2.5501 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8400 10.0649 -0.6887 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6453 9.8214 1.0823 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2169 9.8906 -1.1835 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1818 7.3869 -1.6316 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6102 7.3175 0.6343 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4908 6.7983 1.2083 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0623 6.8675 -1.0577 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0273 4.3638 -1.5058 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4557 4.2946 0.7602 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5697 5.2129 -1.6420 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1253 3.1566 -2.5283 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.2588 -1.8956 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0376 1.7528 -0.4893 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4385 3.8386 0.2938 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2183 0.9349 0.0381 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3357 1.3720 -0.7672 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3827 2.0407 2.1328 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2491 1.8912 2.9976 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3088 0.0000 2.2082 H 0 0 0 0 0 0 0 0 0 0 0 0 18.0792 19.9024 -0.9634 H 0 0 0 0 0 0 0 0 0 0 0 0 19.1651 18.4479 -2.3875 H 0 0 0 0 0 0 0 0 0 0 0 0 17.6504 19.9709 -3.2294 H 0 0 0 0 0 0 0 0 0 0 0 0 15.8745 15.6789 -0.1997 H 0 0 0 0 0 0 0 0 0 0 0 0 18.1282 15.9415 -0.6183 H 0 0 0 0 0 0 0 0 0 0 0 0 17.0421 17.3960 0.8057 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 39 1 0 0 0 0 2 8 2 0 0 0 0 2 29 1 0 0 0 0 2 25 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 29 2 0 0 0 0 4 9 1 0 0 0 0 5 7 2 0 0 0 0 5 40 1 0 0 0 0 6 9 2 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 10 1 0 0 0 0 10 12 1 0 0 0 0 10 13 2 0 0 0 0 11 12 2 0 0 0 0 11 15 1 0 0 0 0 11 21 1 0 0 0 0 12 41 1 0 0 0 0 13 14 1 0 0 0 0 13 42 1 0 0 0 0 14 15 2 0 0 0 0 14 23 1 0 0 0 0 15 43 1 0 0 0 0 16 17 1 0 0 0 0 16 44 1 0 0 0 0 17 18 2 0 0 0 0 17 19 1 0 0 0 0 19 37 1 0 0 0 0 19 45 1 0 0 0 0 20 37 1 0 0 0 0 20 46 1 0 0 0 0 20 47 1 0 0 0 0 20 48 1 0 0 0 0 21 22 1 0 0 0 0 22 49 1 0 0 0 0 22 50 1 0 0 0 0 22 51 1 0 0 0 0 23 24 1 0 0 0 0 24 52 1 0 0 0 0 24 53 1 0 0 0 0 24 54 1 0 0 0 0 25 26 1 0 0 0 0 25 55 1 0 0 0 0 26 27 1 0 0 0 0 26 56 1 0 0 0 0 26 57 1 0 0 0 0 27 28 1 0 0 0 0 27 58 1 0 0 0 0 27 59 1 0 0 0 0 28 30 1 0 0 0 0 28 60 1 0 0 0 0 28 61 1 0 0 0 0 30 31 1 0 0 0 0 30 62 1 0 0 0 0 30 63 1 0 0 0 0 31 34 1 0 0 0 0 31 32 1 0 0 0 0 32 33 1 0 0 0 0 32 64 1 0 0 0 0 32 65 1 0 0 0 0 33 66 1 0 0 0 0 33 67 1 0 0 0 0 33 68 1 0 0 0 0 34 35 1 0 0 0 0 34 69 1 0 0 0 0 34 70 1 0 0 0 0 35 71 1 0 0 0 0 35 72 1 0 0 0 0 35 73 1 0 0 0 0 36 37 1 0 0 0 0 36 74 1 0 0 0 0 36 75 1 0 0 0 0 36 76 1 0 0 0 0 37 38 1 0 0 0 0 38 77 1 0 0 0 0 38 78 1 0 0 0 0 38 79 1 0 0 0 0 M END > (518) 517 > (518) C28H41N7O3 > (518) 523.677 > (518) FGFR-P517 > (518) Pyrido[2,3-d]pyrimidine 12 > (518) FGFR-1 Tyrosine Kinase > (518) 28 > (518) BINDDB > (518) <2007 > (518) P > (518) TRAIN $$$$ SU11248 csChFnd70/04170815452D 56 58 0 0 0 0 0 0 0 0999 V2000 1.8032 3.8706 -1.9390 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5050 2.1849 -2.4827 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7498 1.3169 -3.4535 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2939 2.1201 -3.8864 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3555 4.6893 -2.3705 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6165 3.8143 -3.3506 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7837 6.4589 -2.8447 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0688 6.4374 -2.0063 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0346 4.9057 -3.6017 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8012 7.6712 -2.8498 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2908 7.7618 -1.0796 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2370 9.2828 -0.6836 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4380 11.0322 -0.0369 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9598 12.0499 -0.1299 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5598 10.9380 -0.5378 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9987 9.3753 -0.3667 N 0 0 3 0 0 0 0 0 0 0 0 0 1.6863 11.4573 -0.7704 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2419 11.6748 0.3716 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8642 13.9429 0.1464 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0501 14.9299 -1.0734 O 0 0 0 0 0 0 0 0 0 0 0 0 4.5708 14.5798 1.7511 N 0 0 3 0 0 0 0 0 0 0 0 0 4.4758 16.4609 2.0258 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1341 16.8334 3.9483 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0390 18.7197 4.2237 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5199 19.4641 3.3399 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7339 21.4357 3.2014 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0206 19.1390 6.0856 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8538 18.9389 6.8281 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.3826 -2.0673 F 0 0 0 0 0 0 0 0 0 0 0 0 0.8327 4.5509 -1.1877 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5094 0.0000 -3.8743 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2537 1.4303 -4.6427 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0716 4.5870 -4.2432 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9587 7.6343 -0.6577 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7945 8.3980 -0.3793 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0167 11.3792 0.4753 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6215 12.7851 -1.2588 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0654 10.5831 -1.6956 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9005 12.0289 -0.8312 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1592 12.8087 1.2160 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9708 10.6515 1.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4225 13.7926 2.7240 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7013 17.0567 1.6400 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4231 16.9992 1.2462 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9087 16.2375 4.3340 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1869 16.2950 4.7279 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4097 18.9088 2.0419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3501 19.1674 4.0812 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8595 21.7327 2.3948 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5727 21.9967 2.6164 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9226 21.9822 4.4942 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5819 20.4737 6.2647 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1398 18.2581 6.7593 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7269 19.8473 6.1810 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8331 19.2126 8.2174 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3077 17.6145 6.6145 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 M END > (519) 518 > (519) C22H27FN4O2 > (519) 398.4793 > (519) FGFR-P518 > (519) SU11248 > (519) FGFR-1 Tyrosine Kinase > (519) 2900 > (519) BINDDB > (519) <2007 > (519) P > (519) TRAIN $$$$ SU11248 analog 12a csChFnd70/04170815452D 56 58 0 0 0 0 0 0 0 0999 V2000 1.5419 3.9723 -1.9911 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2359 2.2440 -2.5488 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5113 1.3521 -3.5439 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0978 2.1744 -3.9896 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1356 4.8131 -2.4335 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4302 3.9146 -3.4407 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6294 6.6285 -2.9208 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8687 6.6077 -2.0596 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8848 5.0341 -3.6997 N 0 0 3 0 0 0 0 0 0 0 0 0 6.6744 7.8729 -2.9275 O 0 0 0 0 0 0 0 0 0 0 0 0 3.0709 7.9678 -1.1077 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0432 9.5291 -0.7013 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3041 11.3239 -0.0371 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7867 12.3697 -0.1317 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3488 11.2288 -0.5510 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8525 9.6231 -0.3767 N 0 0 3 0 0 0 0 0 0 0 0 0 1.4253 11.7630 -0.7896 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1567 11.9828 0.3819 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6894 14.3131 0.1534 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8806 15.3272 -1.0983 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3887 14.9660 1.8015 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2920 16.8973 2.0849 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9417 17.2786 4.0593 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8447 19.2153 4.3435 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2850 19.9809 3.4369 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5058 22.0051 3.2958 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8264 19.6445 6.2555 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7087 19.4378 7.0174 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5455 4.6707 -1.2195 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.5863 -2.2080 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2627 0.0000 -3.9752 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0826 1.4645 -4.7655 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9492 4.7064 -4.3586 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7032 7.8374 -0.6738 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6693 8.6195 -0.3912 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7378 11.6828 0.4891 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3596 13.1265 -1.2907 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7875 10.8661 -1.7402 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8325 12.3472 -0.8531 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0727 13.1465 1.2499 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9051 10.9314 1.0519 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2362 14.1571 2.8001 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5504 17.5090 1.6891 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2111 17.4511 1.2851 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6831 16.6671 4.4552 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0224 16.7248 4.8591 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1716 19.4117 2.1036 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0839 19.6761 4.1978 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6996 22.5653 4.6238 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6614 22.3102 2.4676 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3135 22.5821 2.6958 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3764 21.0148 6.4404 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9216 18.7398 6.9468 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1741 18.0778 6.7970 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6053 20.3705 6.3536 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6876 19.7177 8.4442 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 29 1 0 0 0 0 2 3 2 0 0 0 0 2 30 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 M END > (520) 519 > (520) C22H28N4O2 > (520) 380.4888 > (520) FGFR-P519 > (520) SU11248 analog 12a > (520) FGFR-1 Tyrosine Kinase > (520) 880 > (520) BINDDB > (520) <2007 > (520) P > (520) TRAIN $$$$ 1,6-naphthyridin 38 csChFnd70/04170815452D 82 85 0 0 0 0 0 0 0 0999 V2000 7.8538 12.9682 0.8489 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6232 10.5114 0.1511 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9395 11.5545 -0.6247 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1130 14.1400 0.0912 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7043 13.4217 -0.6696 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8423 16.0056 0.0639 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7009 16.2543 -1.4410 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1541 17.0653 -0.7116 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1498 11.2330 0.8505 N 0 0 0 0 0 0 0 0 0 0 0 0 11.9277 14.5048 -1.4014 N 0 0 0 0 0 0 0 0 0 0 0 0 9.9353 19.0400 -0.7762 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1479 21.6309 -1.4779 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3481 19.7854 -1.4199 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3136 20.1543 -0.1862 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1046 21.9988 -0.2479 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5254 22.7365 -0.8960 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0106 17.3249 -2.2172 N 0 0 3 0 0 0 0 0 0 0 0 0 14.4946 16.5708 -2.9198 C 0 0 0 0 0 0 0 0 0 0 0 0 14.6863 14.9531 -2.8738 O 0 0 0 0 0 0 0 0 0 0 0 0 15.7659 17.6101 -3.6732 N 0 0 3 0 0 0 0 0 0 0 0 0 16.8440 15.4967 -5.9358 C 0 0 0 0 0 0 0 0 0 0 0 0 18.5948 18.2555 -5.1997 C 0 0 0 0 0 0 0 0 0 0 0 0 17.3789 16.7904 -4.4368 C 0 0 0 0 0 0 0 0 0 0 0 0 18.3825 15.7628 -2.9726 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6002 22.3590 -2.1055 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4849 24.2712 -2.1276 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4480 23.0864 0.3279 O 0 0 0 0 0 0 0 0 0 0 0 0 12.1420 24.9749 0.2263 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8425 8.6563 0.2026 N 0 0 3 0 0 0 0 0 0 0 0 0 11.4681 7.9299 -0.1044 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6514 5.9338 -0.3565 C 0 0 0 0 0 0 0 0 0 0 0 0 12.7835 8.8826 -0.1779 O 0 0 0 0 0 0 0 0 0 0 0 0 8.3061 7.4961 0.5904 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4912 6.8295 -1.1698 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8865 5.6180 -0.7648 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1256 4.9954 -2.4089 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6096 3.8468 -2.1799 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9195 3.2738 -3.9901 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6363 4.2916 -4.8571 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0033 3.7659 -6.5175 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6539 2.2229 -7.3113 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9379 1.2058 -6.4447 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5752 1.7344 -4.7869 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6403 13.4945 1.4378 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1276 10.9466 -1.1863 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6469 16.5937 0.6306 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2753 18.9254 -1.8735 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5433 19.5808 0.3191 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3660 24.1748 -0.9427 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8576 18.6157 -2.2538 H 0 0 0 0 0 0 0 0 0 0 0 0 15.6131 18.9010 -3.7098 H 0 0 0 0 0 0 0 0 0 0 0 0 16.1292 16.2285 -6.9789 H 0 0 0 0 0 0 0 0 0 0 0 0 18.0442 14.8867 -6.5040 H 0 0 0 0 0 0 0 0 0 0 0 0 15.9779 14.4529 -5.3924 H 0 0 0 0 0 0 0 0 0 0 0 0 18.9758 19.1773 -4.1319 H 0 0 0 0 0 0 0 0 0 0 0 0 19.7949 17.6455 -5.7679 H 0 0 0 0 0 0 0 0 0 0 0 0 17.8797 18.9875 -6.2428 H 0 0 0 0 0 0 0 0 0 0 0 0 17.5163 14.7192 -2.4291 H 0 0 0 0 0 0 0 0 0 0 0 0 19.5825 15.1531 -3.5409 H 0 0 0 0 0 0 0 0 0 0 0 0 18.7634 16.6846 -1.9047 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6370 24.7841 -0.7679 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5455 24.8133 -2.9742 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1844 24.6746 -2.6578 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3164 25.6862 0.7263 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8976 25.3547 -1.1634 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9787 25.3241 1.0385 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3274 5.3162 -0.3311 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2912 5.6618 -1.6417 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4681 5.3798 0.7211 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7474 6.3532 1.3866 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3020 8.2510 1.3368 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0499 7.9726 -1.9660 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4953 6.0746 -1.9162 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3280 4.4749 0.0314 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8825 6.3729 -0.0184 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0038 2.6671 -1.4131 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5582 4.5648 -1.4628 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1280 5.4969 -4.2372 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 4.5605 -7.1945 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1585 1.8118 -8.6081 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4458 0.0000 -7.0646 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5819 0.9426 -4.1122 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 44 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 45 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 46 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 47 1 0 0 0 0 14 15 1 0 0 0 0 14 48 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 49 1 0 0 0 0 17 18 1 0 0 0 0 17 50 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 51 1 0 0 0 0 21 23 1 0 0 0 0 21 52 1 0 0 0 0 21 53 1 0 0 0 0 21 54 1 0 0 0 0 22 23 1 0 0 0 0 22 55 1 0 0 0 0 22 56 1 0 0 0 0 22 57 1 0 0 0 0 23 24 1 0 0 0 0 24 58 1 0 0 0 0 24 59 1 0 0 0 0 24 60 1 0 0 0 0 25 26 1 0 0 0 0 26 61 1 0 0 0 0 26 62 1 0 0 0 0 26 63 1 0 0 0 0 27 28 1 0 0 0 0 28 64 1 0 0 0 0 28 65 1 0 0 0 0 28 66 1 0 0 0 0 29 30 1 0 0 0 0 29 33 1 0 0 0 0 30 31 1 0 0 0 0 30 32 2 0 0 0 0 31 67 1 0 0 0 0 31 68 1 0 0 0 0 31 69 1 0 0 0 0 33 34 1 0 0 0 0 33 70 1 0 0 0 0 33 71 1 0 0 0 0 34 35 1 0 0 0 0 34 72 1 0 0 0 0 34 73 1 0 0 0 0 35 36 1 0 0 0 0 35 74 1 0 0 0 0 35 75 1 0 0 0 0 36 37 1 0 0 0 0 37 38 1 0 0 0 0 37 76 1 0 0 0 0 37 77 1 0 0 0 0 38 43 1 0 0 0 0 38 39 2 0 0 0 0 39 40 1 0 0 0 0 39 78 1 0 0 0 0 40 41 2 0 0 0 0 40 79 1 0 0 0 0 41 42 1 0 0 0 0 41 80 1 0 0 0 0 42 43 2 0 0 0 0 42 81 1 0 0 0 0 43 82 1 0 0 0 0 M END > (53) 51 > (53) C33H39N5O5 > (53) 585.7016 > (53) FGFR-P51 > (53) 1,6-naphthyridine 38 > (53) FGFR-1 Tyrosine Kinase > (53) 1500 > (53) BINDDB > (53) <2007 > (53) P > (53) TRAIN $$$$ SU11248 analog 12c csChFnd70/04170815452D 56 58 0 0 0 0 0 0 0 0999 V2000 2.2318 3.8701 -1.9368 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9332 2.1850 -2.4803 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1755 1.3174 -3.4536 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7185 2.1211 -3.8910 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7828 4.6902 -2.3714 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0422 3.8161 -3.3559 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2102 6.4608 -2.8503 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4968 6.4387 -2.0076 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4587 4.9082 -3.6105 N 0 0 3 0 0 0 0 0 0 0 0 0 7.2278 7.6734 -2.8572 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7208 7.7625 -1.0776 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6678 9.2839 -0.6828 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8708 11.0337 -0.0403 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3918 12.0515 -0.1291 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9906 10.9395 -0.5343 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4309 9.3764 -0.3703 N 0 0 3 0 0 0 0 0 0 0 0 0 2.1159 11.4587 -0.7617 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6761 11.6765 0.3643 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2966 13.9448 0.1495 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4794 14.9332 -1.0701 O 0 0 0 0 0 0 0 0 0 0 0 0 5.0066 14.5802 1.7559 N 0 0 3 0 0 0 0 0 0 0 0 0 4.9120 16.4615 2.0327 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5745 16.8324 3.9569 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4795 18.7188 4.2344 N 0 0 0 0 0 0 0 0 0 0 0 0 2.9578 19.4641 3.3547 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1716 21.4363 3.2172 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4655 19.1365 6.0974 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3012 18.9361 6.8353 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.1533 -1.9426 Cl 0 0 0 0 0 0 0 0 0 0 0 0 1.2623 4.5497 -1.1825 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9341 0.0000 -3.8736 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6768 1.4313 -4.6503 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4942 4.5902 -4.2553 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3893 7.6344 -0.6523 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2271 8.3992 -0.3859 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4492 11.3796 0.4858 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0496 12.7870 -1.2491 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4926 10.5848 -1.6863 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3320 12.0317 -0.8401 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5952 12.8101 1.2099 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4070 10.6526 1.0157 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8608 13.7917 2.7288 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1368 17.0583 1.6445 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8570 17.0007 1.2558 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3498 16.2357 4.3450 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6295 16.2932 4.7337 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8447 18.9097 2.0560 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7896 19.1664 4.0986 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0084 21.9979 2.6353 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3630 21.9819 4.5104 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2954 21.7342 2.4079 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0267 20.4713 6.2788 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5863 18.2546 6.7724 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2835 19.2085 8.2255 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7549 17.6117 6.6194 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1725 19.8455 6.1871 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 M END > (521) 520 > (521) C22H27ClN4O2 > (521) 414.9339 > (521) FGFR-P520 > (521) SU11248 analog 12c > (521) FGFR-1 Tyrosine Kinase > (521) 170 > (521) BINDDB > (521) <2007 > (521) P > (521) TRAIN $$$$ SU11248 analog 12d csChFnd70/04170815452D 56 58 0 0 0 0 0 0 0 0999 V2000 2.4073 3.8704 -1.9423 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1091 2.1863 -2.4858 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3538 1.3167 -3.4521 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8997 2.1171 -3.8825 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9611 4.6874 -2.3697 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2232 3.8113 -3.3475 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3911 6.4542 -2.8404 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6747 6.4351 -2.0057 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6416 4.9006 -3.5962 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4092 7.6657 -2.8454 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8959 7.7609 -1.0822 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8423 9.2814 -0.6857 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0429 11.0291 -0.0356 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5659 12.0478 -0.1324 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1662 10.9368 -0.5426 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6033 9.3726 -0.3653 N 0 0 3 0 0 0 0 0 0 0 0 0 2.2937 11.4572 -0.7792 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8463 11.6707 0.3754 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4711 13.9406 0.1430 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6605 14.9268 -1.0766 O 0 0 0 0 0 0 0 0 0 0 0 0 5.1745 14.5782 1.7466 N 0 0 3 0 0 0 0 0 0 0 0 0 5.0803 16.4594 2.0201 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7346 16.8329 3.9415 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6401 18.7190 4.2160 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1238 19.4642 3.3285 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3397 21.4352 3.1899 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6179 19.1390 6.0774 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4490 18.9378 6.8240 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.0663 -1.9091 Br 0 0 0 0 0 0 0 0 0 0 0 0 1.4357 4.5517 -1.1939 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1124 0.0000 -3.8723 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8601 1.4254 -4.6361 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6792 4.5809 -4.2358 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5629 7.6349 -0.6629 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3983 8.3950 -0.3760 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6218 11.3808 0.4648 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2310 12.7845 -1.2689 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6742 10.5829 -1.7048 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5071 12.0239 -0.8261 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7629 12.8048 1.2192 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5735 10.6474 1.0307 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0235 13.7918 2.7193 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3069 17.0541 1.6370 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0299 16.9981 1.2382 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5081 16.2381 4.3247 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7849 16.2941 4.7235 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0165 18.9085 2.0305 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9523 19.1684 4.0670 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1802 21.9968 2.6022 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5255 21.9818 4.4829 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4671 21.7312 2.3860 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1799 20.4739 6.2550 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7349 18.2592 6.7493 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4253 19.2119 8.2130 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9023 17.6132 6.6120 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3241 19.8451 6.1787 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 M END > (522) 521 > (522) C22H27BrN4O2 > (522) 459.3849 > (522) FGFR-P521 > (522) SU11248 analog 12d > (522) FGFR-1 Tyrosine Kinase > (522) 730 > (522) BINDDB > (522) <2007 > (522) P > (522) TRAIN $$$$ SU11248 analog 12e csChFnd70/04170815452D 50 52 0 0 0 0 0 0 0 0999 V2000 2.3409 3.8385 -0.3167 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2764 2.0850 -0.7018 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4625 1.3706 -1.8546 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7159 2.3952 -2.6274 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5993 4.8797 -1.0902 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8007 4.1608 -2.2551 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5112 7.0054 -2.1295 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0186 6.7524 -0.9665 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9109 5.4611 -2.8398 N 0 0 3 0 0 0 0 0 0 0 0 0 6.2579 8.3747 -2.4000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.1864 7.9933 0.0264 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8821 9.6864 0.1507 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7916 11.8449 0.2883 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1533 12.5776 0.3866 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9392 11.2056 0.3024 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6232 10.1128 0.1500 N 0 0 3 0 0 0 0 0 0 0 0 0 0.9887 11.3675 0.3653 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4853 12.8268 0.3338 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7506 14.4431 0.5498 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5524 15.3250 -0.7464 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6019 15.1714 2.1356 N 0 0 3 0 0 0 0 0 0 0 0 0 3.2017 17.0254 2.2977 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1062 17.5168 4.2218 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7050 19.3759 4.3845 N 0 0 0 0 0 0 0 0 0 0 0 0 0.9525 19.7572 3.7308 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9047 19.9634 6.1896 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0574 1.0668 0.0459 F 0 0 0 0 0 0 0 0 0 0 0 0 1.4144 4.3983 0.5765 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4056 0.0000 -2.1504 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6329 1.8237 -3.5228 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8523 5.2772 -3.6574 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0033 7.6690 0.7080 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5756 9.2917 0.0638 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5521 11.2952 1.7107 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5999 12.6108 -0.1911 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4033 10.3138 -0.3784 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8665 13.1721 -0.9859 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3271 14.0055 1.1032 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4871 12.0131 0.9171 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7599 14.4679 3.1693 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2172 17.7845 1.6663 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9566 17.2954 1.6791 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0909 16.7576 4.8532 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3514 17.2467 4.8405 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 19.0201 4.4760 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6889 21.1423 3.8667 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8683 19.3923 2.3649 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2395 19.7485 6.6112 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5997 21.3441 6.2733 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0228 19.2337 7.0239 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 28 1 0 0 0 0 2 3 2 0 0 0 0 2 27 1 0 0 0 0 3 4 1 0 0 0 0 3 29 1 0 0 0 0 4 6 2 0 0 0 0 4 30 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 31 1 0 0 0 0 11 12 1 0 0 0 0 11 32 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 33 1 0 0 0 0 17 34 1 0 0 0 0 17 35 1 0 0 0 0 17 36 1 0 0 0 0 18 37 1 0 0 0 0 18 38 1 0 0 0 0 18 39 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 26 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 M END > (523) 522 > (523) C20H23FN4O2 > (523) 370.4257 > (523) FGFR-P522 > (523) SU11248 analog 12e > (523) FGFR-1 Tyrosine Kinase > (523) 1600 > (523) BINDDB > (523) <2007 > (523) P > (523) TRAIN $$$$ SU11248 analog 12f csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 3.4912 3.8809 -0.3202 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4260 2.1081 -0.7096 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6253 1.3857 -1.8751 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8924 2.4217 -2.6565 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7636 4.9336 -1.1023 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9782 4.2067 -2.2801 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6965 7.0828 -2.1530 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1875 6.8270 -0.9771 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1007 5.5214 -2.8713 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4515 8.4672 -2.4265 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3461 8.0816 0.0267 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0495 9.7936 0.1524 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9801 11.9759 0.2915 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3237 12.7165 0.3909 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0962 11.3295 0.3057 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8098 10.2245 0.1516 N 0 0 3 0 0 0 0 0 0 0 0 0 2.1241 11.4932 0.3693 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6924 12.9685 0.3375 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9166 14.6028 0.5559 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7162 15.4944 -0.7547 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7662 15.3391 2.1592 N 0 0 3 0 0 0 0 0 0 0 0 0 4.3616 17.2135 2.3231 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2650 17.7104 4.2684 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1936 1.0786 0.0464 F 0 0 0 0 0 0 0 0 0 0 0 0 3.4481 20.0534 6.2683 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6029 20.8934 6.2766 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3832 21.5386 4.3558 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3444 20.0752 3.3181 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8593 19.5900 4.4329 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5545 4.4470 0.5829 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5677 0.0000 -2.1742 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8195 1.8439 -3.5617 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0525 5.3355 -3.6978 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1499 7.7538 0.7159 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7726 9.3944 0.0645 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6827 11.4201 1.7296 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7310 12.7501 -0.1933 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5322 10.4278 -0.3826 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0779 13.3176 -0.9968 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5325 14.1603 1.1153 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7054 12.1460 0.9273 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9260 14.6279 3.2045 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3882 17.9811 1.6848 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1028 17.4866 1.6976 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2384 16.9428 4.9068 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5241 17.4373 4.8940 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4120 20.9904 6.7618 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4503 18.8742 7.0807 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6046 19.9190 6.6008 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5523 21.9952 7.1899 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 21.6021 3.9910 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0208 22.8065 4.1645 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4816 18.9478 3.1313 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7955 20.5745 2.0541 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 24 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 29 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 27 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 28 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 28 29 1 0 0 0 0 28 53 1 0 0 0 0 28 54 1 0 0 0 0 M END > (524) 523 > (524) C22H25FN4O2 > (524) 396.4635 > (524) FGFR-P523 > (524) SU11248 analog 12f > (524) FGFR-1 Tyrosine Kinase > (524) 3900 > (524) BINDDB > (524) <2007 > (524) P > (524) TRAIN $$$$ SU11248 analog 12g csChFnd70/04170815452D 57 60 0 0 0 0 0 0 0 0999 V2000 2.6639 3.8809 -0.3202 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5987 2.1081 -0.7096 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7980 1.3857 -1.8751 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0650 2.4217 -2.6565 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9363 4.9335 -1.1022 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1508 4.2067 -2.2801 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8692 7.0827 -2.1530 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3600 6.8269 -0.9771 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2733 5.5213 -2.8712 N 0 0 3 0 0 0 0 0 0 0 0 0 6.6241 8.4671 -2.4265 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5188 8.0815 0.0267 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2222 9.7934 0.1524 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1528 11.9757 0.2915 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4963 12.7164 0.3909 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2689 11.3294 0.3057 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9825 10.2244 0.1516 N 0 0 3 0 0 0 0 0 0 0 0 0 1.2968 11.4931 0.3693 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8650 12.9684 0.3375 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0892 14.6026 0.5559 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8889 15.4942 -0.7547 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9389 15.3389 2.1592 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5343 17.2133 2.3231 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3663 1.0786 0.0464 F 0 0 0 0 0 0 0 0 0 0 0 0 3.1778 19.6974 4.4426 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8849 16.7634 5.1278 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7466 17.3270 7.0528 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0022 20.1759 6.3873 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4982 19.2377 7.1489 N 0 0 3 0 0 0 0 0 0 0 0 0 3.4377 17.7102 4.2684 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1787 19.8031 8.9663 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7272 4.4469 0.5829 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7404 0.0000 -2.1742 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9922 1.8439 -3.5617 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2251 5.3354 -3.6978 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3226 7.7537 0.7158 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9453 9.3943 0.0645 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8554 11.4200 1.7296 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9037 12.7500 -0.1933 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7050 10.4277 -0.3826 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2505 13.3174 -0.9967 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7052 14.1601 1.1153 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8780 12.1458 0.9272 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0987 14.6277 3.2044 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5608 17.9809 1.6848 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2755 17.4864 1.6976 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9894 20.0871 3.7451 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3065 20.3781 3.8828 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0897 15.3478 5.0576 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6761 17.1069 4.4411 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6308 16.6695 7.6636 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9486 16.9667 7.7429 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1983 19.8024 7.0806 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7981 21.5875 6.5148 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6536 17.3276 4.9209 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2996 19.4443 9.7819 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9992 21.2235 8.9998 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 19.1611 9.4655 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 31 1 0 0 0 0 2 3 2 0 0 0 0 2 23 1 0 0 0 0 3 4 1 0 0 0 0 3 32 1 0 0 0 0 4 6 2 0 0 0 0 4 33 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 34 1 0 0 0 0 11 12 1 0 0 0 0 11 35 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 17 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 18 42 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 43 1 0 0 0 0 22 29 1 0 0 0 0 22 44 1 0 0 0 0 22 45 1 0 0 0 0 24 29 1 0 0 0 0 24 27 1 0 0 0 0 24 46 1 0 0 0 0 24 47 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 48 1 0 0 0 0 25 49 1 0 0 0 0 26 28 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 30 1 0 0 0 0 29 54 1 0 0 0 0 30 55 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 M END > (525) 524 > (525) C23H27FN4O2 > (525) 410.4903 > (525) FGFR-P524 > (525) SU11248 analog 12g > (525) FGFR-1 Tyrosine Kinase > (525) 200 > (525) BINDDB > (525) <2007 > (525) P > (525) TRAIN $$$$ SU11248 analog 12h csChFnd70/04170815452D 55 58 0 0 0 0 0 0 0 0999 V2000 2.5541 3.9162 -0.3231 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4883 2.1273 -0.7160 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6984 1.3984 -1.8923 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9771 2.4438 -2.6807 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8380 4.9785 -1.1123 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0637 4.2450 -2.3009 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7886 7.1474 -2.1727 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2657 6.8892 -0.9861 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1964 5.5718 -2.8974 N 0 0 3 0 0 0 0 0 0 0 0 0 6.5504 8.5445 -2.4487 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4167 8.1553 0.0269 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1265 9.8828 0.1538 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0747 12.0850 0.2942 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4032 12.8325 0.3944 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1646 11.4327 0.3085 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9029 10.3178 0.1530 N 0 0 3 0 0 0 0 0 0 0 0 0 1.1744 11.5979 0.3727 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8027 13.0867 0.3406 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9923 14.7358 0.5609 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7902 15.6356 -0.7615 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8407 15.4789 2.1789 N 0 0 3 0 0 0 0 0 0 0 0 0 3.4324 17.3705 2.3443 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2446 1.0884 0.0468 F 0 0 0 0 0 0 0 0 0 0 0 0 3.3349 17.8718 4.3073 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5118 20.2349 6.3200 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1719 22.2319 6.4462 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1327 22.2702 3.4456 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4621 20.2735 3.2890 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9255 19.7686 4.4733 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7737 22.7048 5.2559 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6087 4.4875 0.5882 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6404 0.0000 -2.1940 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9127 1.8607 -3.5942 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1569 5.3842 -3.7316 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2097 7.8244 0.7224 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8745 9.4800 0.0651 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7290 11.5242 1.7454 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7778 12.8664 -0.1950 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5772 10.5228 -0.3860 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1916 13.4390 -1.0058 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6413 14.2893 1.1255 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8249 12.2567 0.9357 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0019 14.7611 3.2336 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4683 18.1449 1.7001 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1621 17.6459 1.7132 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2990 17.0972 4.9515 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6053 17.5962 4.9385 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6266 19.8807 7.1684 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3325 19.5167 6.7463 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7905 22.5721 7.7979 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3739 22.9496 6.0878 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3046 22.9890 3.0002 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 22.6380 2.6273 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2661 19.5561 3.6670 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8108 19.9475 1.9252 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 31 1 0 0 0 0 2 3 2 0 0 0 0 2 23 1 0 0 0 0 3 4 1 0 0 0 0 3 32 1 0 0 0 0 4 6 2 0 0 0 0 4 33 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 34 1 0 0 0 0 11 12 1 0 0 0 0 11 35 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 17 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 18 42 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 43 1 0 0 0 0 22 24 1 0 0 0 0 22 44 1 0 0 0 0 22 45 1 0 0 0 0 24 29 1 0 0 0 0 24 46 1 0 0 0 0 24 47 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 48 1 0 0 0 0 25 49 1 0 0 0 0 26 30 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 30 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 M END > (526) 525 > (526) C22H25FN4O3 > (526) 412.4629 > (526) FGFR-P525 > (526) SU11248 analog 12h > (526) FGFR-1 Tyrosine Kinase > (526) 2600 > (526) BINDDB > (526) <2007 > (526) P > (526) TRAIN $$$$ SU11248 analog 12i csChFnd70/04170815452D 48 51 0 0 0 0 0 0 0 0999 V2000 2.0368 3.8385 -0.3167 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9724 2.0850 -0.7018 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1585 1.3706 -1.8546 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4118 2.3953 -2.6275 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2954 4.8797 -1.0902 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4967 4.1608 -2.2552 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2072 7.0055 -2.1296 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7146 6.7525 -0.9665 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6069 5.4611 -2.8399 N 0 0 3 0 0 0 0 0 0 0 0 0 5.9539 8.3748 -2.4001 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8824 7.9934 0.0264 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5781 9.6865 0.1507 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4876 11.8451 0.2883 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8493 12.5777 0.3866 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6353 11.2058 0.3024 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3192 10.1130 0.1500 N 0 0 3 0 0 0 0 0 0 0 0 0 0.6847 11.3677 0.3653 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1813 12.8269 0.3338 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4466 14.4433 0.5498 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2485 15.3252 -0.7464 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2980 15.1716 2.1357 N 0 0 3 0 0 0 0 0 0 0 0 0 0.7534 1.0668 0.0459 F 0 0 0 0 0 0 0 0 0 0 0 0 2.8978 17.0256 2.2977 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8037 17.5096 4.1929 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2721 18.0649 5.0768 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2451 17.4174 5.0920 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2088 17.8717 6.8292 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1361 18.4979 6.8145 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6331 18.3881 7.6301 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1103 4.3984 0.5765 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1016 0.0000 -2.1504 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3288 1.8237 -3.5229 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5484 5.2772 -3.6575 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6992 7.6691 0.7080 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2715 9.2918 0.0638 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2481 11.2954 1.7107 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2959 12.6109 -0.1911 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0993 10.3140 -0.3784 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5626 13.1722 -0.9859 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0232 14.0057 1.1032 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1831 12.0133 0.9171 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4560 14.4681 3.1694 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9131 17.7848 1.6663 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6526 17.2956 1.6791 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5067 18.1576 4.4161 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0743 16.9964 4.4431 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.8035 7.5388 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2738 18.9311 7.5125 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 22 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 23 1 0 0 0 0 21 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 2 0 0 0 0 24 26 1 0 0 0 0 25 28 1 0 0 0 0 25 45 1 0 0 0 0 26 27 2 0 0 0 0 26 46 1 0 0 0 0 27 29 1 0 0 0 0 27 47 1 0 0 0 0 28 29 2 0 0 0 0 28 48 1 0 0 0 0 M END > (527) 526 > (527) C22H19FN4O2 > (527) 390.4161 > (527) FGFR-P526 > (527) SU11248 analog 12i > (527) FGFR-1 Tyrosine Kinase > (527) 3100 > (527) BINDDB > (527) <2007 > (527) P > (527) TRAIN $$$$ SU5402 csChFnd70/04170815452D 38 40 0 0 0 0 0 0 0 0999 V2000 5.9710 3.8290 -0.3158 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9063 2.0826 -0.6982 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0904 1.3673 -1.8411 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3444 2.3852 -2.6100 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4303 4.1464 -2.2414 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2292 4.8657 -1.0837 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6484 6.7328 -0.9616 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1400 6.9818 -2.1167 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5391 5.4405 -2.8219 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8856 8.3466 -2.3875 O 0 0 0 0 0 0 0 0 0 0 0 0 6.8164 7.9735 0.0254 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5099 9.6596 0.1481 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5744 11.1858 0.3001 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2428 10.0926 0.1469 N 0 0 3 0 0 0 0 0 0 0 0 0 4.6300 11.3542 0.3640 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0197 11.2549 2.2477 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0752 11.4230 2.3116 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2612 11.6038 0.9865 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2477 11.3722 3.8405 O 0 0 0 0 0 0 0 0 0 0 0 0 9.3844 11.8393 0.2873 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7741 12.5373 0.3828 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3541 14.4368 0.5528 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0446 4.3887 0.5713 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9312 1.2730 -0.1047 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0325 0.0000 -2.1333 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2605 1.8122 -3.4992 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4800 5.2554 -3.6345 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6347 7.6519 0.7030 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2009 9.2837 0.0605 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2464 12.5951 -0.1905 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0420 10.3053 -0.3773 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4032 10.0138 2.8022 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6075 12.3035 2.9889 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.4855 3.8161 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5850 12.5575 0.3215 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2867 14.7834 1.9204 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3617 15.2000 -0.0774 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1100 14.7006 -0.0616 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 23 1 0 0 0 0 2 3 2 0 0 0 0 2 24 1 0 0 0 0 3 4 1 0 0 0 0 3 25 1 0 0 0 0 4 5 2 0 0 0 0 4 26 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 27 1 0 0 0 0 11 12 1 0 0 0 0 11 28 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 29 1 0 0 0 0 15 16 1 0 0 0 0 15 30 1 0 0 0 0 15 31 1 0 0 0 0 16 17 1 0 0 0 0 16 32 1 0 0 0 0 16 33 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 34 1 0 0 0 0 20 21 2 0 0 0 0 20 35 1 0 0 0 0 21 22 1 0 0 0 0 22 36 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 M END > (529) 528 > (529) C17H16N2O3 > (529) 296.325 > (529) FGFR-P528 > (529) SU5402 > (529) FGFR-1 Tyrosine Kinase > (529) 30 > (529) BINDDB > (529) <2007 > (529) P > (529) TRAIN $$$$ SU5416 csChFnd70/04170815452D 32 34 0 0 0 0 0 0 0 0999 V2000 1.7954 3.3127 0.0380 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8325 1.8458 -0.0136 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1026 1.1479 -0.2761 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3424 1.9051 -0.4886 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0385 4.0858 -0.1752 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3266 3.3829 -0.4407 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8950 5.7158 -0.4798 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3626 5.6258 -0.1906 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3990 4.3848 -0.6130 N 0 0 3 0 0 0 0 0 0 0 0 0 5.5881 6.8060 -0.5793 O 0 0 0 0 0 0 0 0 0 0 0 0 2.4260 6.7385 0.0206 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9426 8.1419 0.1360 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3275 9.9872 0.6446 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1473 10.5090 -0.0005 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2600 9.3642 -0.3274 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2161 8.5514 0.7362 N 0 0 3 0 0 0 0 0 0 0 0 0 0.8303 9.4421 -1.0480 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5611 10.8612 1.1768 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8044 3.8581 0.2384 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8695 1.2417 0.1512 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1234 0.0000 -0.3146 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3264 1.3486 -0.6920 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3857 4.1533 -0.8061 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2984 6.5334 0.0973 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9317 11.6153 -0.2220 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9154 7.9186 1.1544 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.5591 -0.2474 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8077 10.3534 -1.7642 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6491 8.4701 -1.6534 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3488 10.9718 0.3333 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1834 11.9107 1.4928 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0437 10.3332 2.0893 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 19 1 0 0 0 0 2 3 2 0 0 0 0 2 20 1 0 0 0 0 3 4 1 0 0 0 0 3 21 1 0 0 0 0 4 6 2 0 0 0 0 4 22 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 23 1 0 0 0 0 11 12 1 0 0 0 0 11 24 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 25 1 0 0 0 0 15 17 1 0 0 0 0 16 26 1 0 0 0 0 17 27 1 0 0 0 0 17 28 1 0 0 0 0 17 29 1 0 0 0 0 18 30 1 0 0 0 0 18 31 1 0 0 0 0 18 32 1 0 0 0 0 M END > (530) 529 > (530) C15H14N2O > (530) 238.2884 > (530) FGFR-P529 > (530) SU5416 > (530) FGFR-1 Tyrosine Kinase > (530) 7080 > (530) BINDDB > (530) <2007 > (530) P > (530) TRAIN $$$$ 1,6-naphthyridin 39 csChFnd70/04170815452D 85 88 0 0 0 0 0 0 0 0999 V2000 11.7681 13.5812 0.0525 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2055 10.9499 -0.1587 C 0 0 0 0 0 0 0 0 0 0 0 0 14.7592 11.7241 -0.5940 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2839 14.4874 -0.3806 C 0 0 0 0 0 0 0 0 0 0 0 0 14.8280 13.5399 -0.7151 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3155 16.3073 -0.4932 C 0 0 0 0 0 0 0 0 0 0 0 0 16.3495 16.0700 -1.2437 C 0 0 0 0 0 0 0 0 0 0 0 0 14.8673 17.0983 -0.9296 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7852 11.8808 0.1455 N 0 0 0 0 0 0 0 0 0 0 0 0 16.2914 14.3676 -1.1313 N 0 0 0 0 0 0 0 0 0 0 0 0 14.9719 19.0135 -1.0667 C 0 0 0 0 0 0 0 0 0 0 0 0 13.8570 21.7082 -2.1750 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7558 19.9187 -2.0501 C 0 0 0 0 0 0 0 0 0 0 0 0 16.2820 19.9127 -0.2061 C 0 0 0 0 0 0 0 0 0 0 0 0 16.3757 21.7023 -0.3364 C 0 0 0 0 0 0 0 0 0 0 0 0 15.1671 22.5987 -1.3223 C 0 0 0 0 0 0 0 0 0 0 0 0 17.9011 16.8715 -1.6812 N 0 0 3 0 0 0 0 0 0 0 0 0 19.3271 15.9078 -1.9855 C 0 0 0 0 0 0 0 0 0 0 0 0 19.2546 14.3366 -1.8769 O 0 0 0 0 0 0 0 0 0 0 0 0 20.8335 16.6858 -2.4103 N 0 0 3 0 0 0 0 0 0 0 0 0 22.0372 14.4048 -4.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 23.9036 16.8306 -3.1931 C 0 0 0 0 0 0 0 0 0 0 0 0 22.3835 15.6383 -2.7411 C 0 0 0 0 0 0 0 0 0 0 0 0 22.8285 14.5851 -1.1195 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6716 22.5920 -3.1341 O 0 0 0 0 0 0 0 0 0 0 0 0 12.8533 24.4348 -3.2063 C 0 0 0 0 0 0 0 0 0 0 0 0 17.6526 22.5801 0.5029 O 0 0 0 0 0 0 0 0 0 0 0 0 17.6719 24.4235 0.3119 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1223 9.1482 -0.0354 N 0 0 3 0 0 0 0 0 0 0 0 0 14.5918 8.2022 -0.0524 C 0 0 0 0 0 0 0 0 0 0 0 0 14.4999 6.2571 -0.2184 C 0 0 0 0 0 0 0 0 0 0 0 0 15.9881 8.9162 0.0660 O 0 0 0 0 0 0 0 0 0 0 0 0 11.4373 8.2831 0.1127 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8290 7.7073 -1.6861 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0694 6.8039 -1.5315 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4613 6.2279 -3.3303 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8177 5.3842 -3.1858 O 0 0 0 0 0 0 0 0 0 0 0 0 6.1297 4.7923 -4.8016 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4037 3.9279 -4.4972 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8949 4.8946 -4.5517 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3117 4.1018 -4.2723 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2369 2.3418 -3.9392 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7455 1.3748 -3.8859 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3283 2.1667 -4.1708 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5853 14.2834 0.3162 H 0 0 0 0 0 0 0 0 0 0 0 0 15.9000 10.9487 -0.8367 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1636 17.0652 -0.2472 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7361 19.2261 -2.7148 H 0 0 0 0 0 0 0 0 0 0 0 0 17.2231 19.2155 0.5619 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2430 23.9937 -1.4217 H 0 0 0 0 0 0 0 0 0 0 0 0 17.9589 18.1251 -1.7678 H 0 0 0 0 0 0 0 0 0 0 0 0 20.8913 17.9395 -2.4969 H 0 0 0 0 0 0 0 0 0 0 0 0 21.7201 15.1552 -5.4115 H 0 0 0 0 0 0 0 0 0 0 0 0 23.1904 13.6254 -4.5024 H 0 0 0 0 0 0 0 0 0 0 0 0 20.9542 13.5554 -3.9342 H 0 0 0 0 0 0 0 0 0 0 0 0 24.1503 17.7094 -2.1135 H 0 0 0 0 0 0 0 0 0 0 0 0 25.0569 16.0513 -3.4392 H 0 0 0 0 0 0 0 0 0 0 0 0 23.5865 17.5809 -4.3485 H 0 0 0 0 0 0 0 0 0 0 0 0 21.7456 13.7356 -0.7974 H 0 0 0 0 0 0 0 0 0 0 0 0 23.9818 13.8056 -1.3655 H 0 0 0 0 0 0 0 0 0 0 0 0 23.0751 15.4638 -0.0399 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8268 24.9783 -4.0122 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7602 24.9691 -1.9009 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1113 24.7629 -3.7611 H 0 0 0 0 0 0 0 0 0 0 0 0 17.8185 24.7541 -1.0546 H 0 0 0 0 0 0 0 0 0 0 0 0 16.4583 24.9603 0.7991 H 0 0 0 0 0 0 0 0 0 0 0 0 18.7535 24.9620 1.0457 H 0 0 0 0 0 0 0 0 0 0 0 0 14.4092 5.9046 -1.5842 H 0 0 0 0 0 0 0 0 0 0 0 0 15.6634 5.6810 0.3407 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3606 5.7789 0.4684 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5599 7.1530 0.9527 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4940 9.1800 0.6641 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7063 8.8375 -2.5262 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7724 6.8105 -2.2377 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1922 5.6736 -0.6915 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1260 7.7005 -0.9800 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3385 7.3580 -4.1704 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4045 5.3311 -3.8818 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9586 5.8927 -5.6722 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0246 3.8658 -5.3836 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9534 6.2695 -4.8119 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1330 4.8572 -4.3139 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.7225 -3.7200 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6871 0.0000 -3.6252 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5064 1.4104 -4.1338 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 45 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 46 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 47 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 48 1 0 0 0 0 14 15 1 0 0 0 0 14 49 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 50 1 0 0 0 0 17 18 1 0 0 0 0 17 51 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 52 1 0 0 0 0 21 23 1 0 0 0 0 21 53 1 0 0 0 0 21 54 1 0 0 0 0 21 55 1 0 0 0 0 22 23 1 0 0 0 0 22 56 1 0 0 0 0 22 57 1 0 0 0 0 22 58 1 0 0 0 0 23 24 1 0 0 0 0 24 59 1 0 0 0 0 24 60 1 0 0 0 0 24 61 1 0 0 0 0 25 26 1 0 0 0 0 26 62 1 0 0 0 0 26 63 1 0 0 0 0 26 64 1 0 0 0 0 27 28 1 0 0 0 0 28 65 1 0 0 0 0 28 66 1 0 0 0 0 28 67 1 0 0 0 0 29 30 1 0 0 0 0 29 33 1 0 0 0 0 30 31 1 0 0 0 0 30 32 2 0 0 0 0 31 68 1 0 0 0 0 31 69 1 0 0 0 0 31 70 1 0 0 0 0 33 34 1 0 0 0 0 33 71 1 0 0 0 0 33 72 1 0 0 0 0 34 35 1 0 0 0 0 34 73 1 0 0 0 0 34 74 1 0 0 0 0 35 36 1 0 0 0 0 35 75 1 0 0 0 0 35 76 1 0 0 0 0 36 37 1 0 0 0 0 36 77 1 0 0 0 0 36 78 1 0 0 0 0 37 38 1 0 0 0 0 38 39 1 0 0 0 0 38 79 1 0 0 0 0 38 80 1 0 0 0 0 39 40 1 0 0 0 0 39 44 2 0 0 0 0 40 41 2 0 0 0 0 40 81 1 0 0 0 0 41 42 1 0 0 0 0 41 82 1 0 0 0 0 42 43 2 0 0 0 0 42 83 1 0 0 0 0 43 44 1 0 0 0 0 43 84 1 0 0 0 0 44 85 1 0 0 0 0 M END > (54) 52 > (54) C34H41N5O5 > (54) 599.7284 > (54) FGFR-P52 > (54) 1,6-naphthyridine 39 > (54) FGFR-1 Tyrosine Kinase > (54) 5100 > (54) BINDDB > (54) <2007 > (54) P > (54) TRAIN $$$$ SU5416 analog 5c csChFnd70/04170815452D 58 61 0 0 0 0 0 0 0 0999 V2000 2.4719 4.0937 -0.3379 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4033 2.2265 -0.7468 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6696 1.4620 -1.9684 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0107 2.5502 -2.7897 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8173 5.2025 -1.1586 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1022 4.4334 -2.3957 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8607 7.4652 -2.2623 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2655 7.1988 -1.0278 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2882 5.8171 -3.0156 N 0 0 3 0 0 0 0 0 0 0 0 0 6.6587 8.9243 -2.5506 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3749 8.5254 0.0269 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1165 10.3282 0.1588 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1207 12.6588 0.3087 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3989 13.4051 0.4095 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1162 11.9601 0.3206 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9694 10.7911 0.1588 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0372 12.1400 0.3879 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9119 13.7304 0.3598 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9496 15.4363 0.5870 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7512 16.2876 -1.3441 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2951 18.3498 -1.1638 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3487 21.0545 -2.9093 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9534 17.9924 -4.2184 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8799 18.8335 -6.1636 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2751 21.8955 -4.8546 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1044 19.1670 -3.0181 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1241 20.7210 -6.0548 N 0 0 0 0 0 0 0 0 0 0 0 0 0.9334 21.5381 -7.9090 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4812 4.6921 0.6105 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3607 1.3607 -0.1124 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6076 0.0000 -2.2814 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9910 1.9378 -3.7401 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2953 5.6191 -3.8831 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1110 8.1815 0.7501 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9938 9.9261 0.0673 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5715 12.0651 1.8226 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6272 13.4667 -0.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4090 11.0183 -0.4044 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3151 14.1043 -1.0468 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7250 14.9844 1.1802 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9911 12.8773 0.9829 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6540 15.6009 1.3453 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0617 16.1345 1.3331 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0468 16.1230 -2.1025 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6390 15.5894 -2.0901 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9994 18.5144 -0.4055 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4071 19.0480 -0.4179 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2342 21.9018 -2.0272 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9556 21.0068 -2.3281 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5559 17.9098 -3.6520 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5508 16.6074 -4.2905 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2729 18.8813 -6.7448 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9941 17.9861 -7.0457 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6776 23.2806 -4.7824 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6726 21.9781 -5.4210 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 20.6900 -8.7396 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3713 22.9347 -7.7883 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2875 21.5965 -8.5751 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 29 1 0 0 0 0 2 3 2 0 0 0 0 2 30 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 1 0 0 0 0 19 42 1 0 0 0 0 19 43 1 0 0 0 0 20 21 1 0 0 0 0 20 44 1 0 0 0 0 20 45 1 0 0 0 0 21 26 1 0 0 0 0 21 46 1 0 0 0 0 21 47 1 0 0 0 0 22 26 1 0 0 0 0 22 25 1 0 0 0 0 22 48 1 0 0 0 0 22 49 1 0 0 0 0 23 26 1 0 0 0 0 23 24 1 0 0 0 0 23 50 1 0 0 0 0 23 51 1 0 0 0 0 24 27 1 0 0 0 0 24 52 1 0 0 0 0 24 53 1 0 0 0 0 25 27 1 0 0 0 0 25 54 1 0 0 0 0 25 55 1 0 0 0 0 27 28 1 0 0 0 0 28 56 1 0 0 0 0 28 57 1 0 0 0 0 28 58 1 0 0 0 0 M END > (531) 530 > (531) C23H30N4O > (531) 378.5162 > (531) FGFR-P530 > (531) SU5416 analog 5c > (531) FGFR-1 Tyrosine Kinase > (531) 4200 > (531) BINDDB > (531) <2007 > (531) P > (531) TRAIN $$$$ SU6668 csChFnd70/04170815452D 41 43 0 0 0 0 0 0 0 0999 V2000 1.9526 3.8746 -0.3198 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8876 2.1073 -0.7068 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0861 1.3837 -1.8632 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3554 2.4138 -2.6405 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2259 4.9241 -1.0965 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4420 4.1961 -2.2675 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1600 7.0657 -2.1412 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6501 6.8135 -0.9727 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5645 5.5058 -2.8543 N 0 0 3 0 0 0 0 0 0 0 0 0 5.9152 8.4467 -2.4142 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8072 8.0692 0.0254 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5091 9.7754 0.1503 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4060 11.9814 0.2922 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7764 12.6877 0.3876 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5624 11.3200 0.3034 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2628 10.2135 0.1503 N 0 0 3 0 0 0 0 0 0 0 0 0 0.5946 11.4903 0.3672 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1014 12.9955 0.3405 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3511 14.6102 0.5556 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1633 15.4159 -1.2721 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7381 17.3385 -1.1041 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5996 17.9967 0.3304 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5133 18.3196 -2.5482 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0148 4.4409 0.5778 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9007 1.2878 -0.1063 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0275 0.0000 -2.1593 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2833 1.8341 -3.5399 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5178 5.3184 -3.6753 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6109 7.7437 0.7099 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2324 9.3949 0.0637 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1538 11.4194 1.7251 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2065 12.7460 -0.1947 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 10.4286 -0.3828 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4830 13.3495 -0.9907 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9245 14.1825 1.1170 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1228 12.1882 0.9302 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1249 14.7660 1.2733 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4037 15.2710 1.2617 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3895 15.2601 -1.9900 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1108 14.7551 -1.9783 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2424 19.5461 -2.3743 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 24 1 0 0 0 0 2 3 2 0 0 0 0 2 25 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 6 2 0 0 0 0 4 27 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 28 1 0 0 0 0 11 12 1 0 0 0 0 11 29 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 30 1 0 0 0 0 17 31 1 0 0 0 0 17 32 1 0 0 0 0 17 33 1 0 0 0 0 18 34 1 0 0 0 0 18 35 1 0 0 0 0 18 36 1 0 0 0 0 19 20 1 0 0 0 0 19 37 1 0 0 0 0 19 38 1 0 0 0 0 20 21 1 0 0 0 0 20 39 1 0 0 0 0 20 40 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 41 1 0 0 0 0 M END > (532) 531 > (532) C18H18N2O3 > (532) 310.3518 > (532) FGFR-P531 > (532) SU6668 > (532) FGFR-1 Tyrosine Kinase > (532) 3000 > (532) BINDDB > (532) <2007 > (532) P > (532) TRAIN $$$$ ZD6474 csChFnd70/04170815452D 54 57 0 0 0 0 0 0 0 0999 V2000 5.0125 14.0750 0.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6886 14.0464 0.3154 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4720 11.6671 0.2562 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0219 12.4333 0.1489 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6513 11.5651 0.0630 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7226 9.9824 0.0834 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1535 9.2159 0.1900 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5177 10.0430 0.2758 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3612 14.8118 0.2166 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7680 12.5267 0.3359 N 0 0 0 0 0 0 0 0 0 0 0 0 3.6381 16.5064 0.1537 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4527 18.9709 -0.3750 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4479 17.3720 -0.5078 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8238 17.2508 0.9503 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8218 18.8483 1.0789 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6397 19.7079 0.4152 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6427 21.8945 0.5947 Br 0 0 0 0 0 0 0 0 0 0 0 0 1.2890 16.6519 -1.2793 F 0 0 0 0 0 0 0 0 0 0 0 0 3.6372 14.8880 0.0224 N 0 0 3 0 0 0 0 0 0 0 0 0 2.6699 14.3377 -0.1454 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3910 9.1403 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9700 9.9878 -0.1062 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1946 7.6405 0.2094 O 0 0 0 0 0 0 0 0 0 0 0 0 6.6873 6.9277 0.3196 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5011 5.1624 0.3253 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8498 4.6293 -1.2390 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7325 2.8577 -1.2518 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9016 2.6346 0.5228 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0836 4.3995 0.5887 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2759 2.1830 -0.9961 N 0 0 3 0 0 0 0 0 0 0 0 0 7.2361 0.4872 -1.1606 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7541 14.7022 0.3816 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5434 12.1444 -0.0186 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6150 9.4436 0.3569 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5294 19.6445 -0.8884 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7468 16.5813 1.4696 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7442 19.4270 1.6986 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8422 10.7258 0.9128 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9841 10.7055 -1.1472 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.1786 -0.1650 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3939 7.2739 -0.6704 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2520 7.2955 1.3898 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7095 4.8240 1.2516 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7011 5.1295 -1.4107 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6192 5.0082 -2.1680 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9503 2.4804 -0.3326 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2846 2.4732 -2.3703 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0293 2.0881 0.6933 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1092 2.2584 1.4336 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8883 4.7749 -0.3117 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5310 4.7358 1.7226 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8499 0.1856 -2.3265 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3938 0.0174 -0.9655 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4350 0.0000 -0.3121 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 9 2 0 0 0 0 1 19 1 0 0 0 0 2 10 2 0 0 0 0 2 9 1 0 0 0 0 2 32 1 0 0 0 0 3 10 1 0 0 0 0 3 8 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 33 1 0 0 0 0 6 7 1 0 0 0 0 6 21 1 0 0 0 0 7 8 2 0 0 0 0 7 23 1 0 0 0 0 8 34 1 0 0 0 0 11 19 1 0 0 0 0 11 13 2 0 0 0 0 11 14 1 0 0 0 0 12 13 1 0 0 0 0 12 16 2 0 0 0 0 12 35 1 0 0 0 0 13 18 1 0 0 0 0 14 15 2 0 0 0 0 14 36 1 0 0 0 0 15 16 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 21 22 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 24 25 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 29 1 0 0 0 0 25 26 1 0 0 0 0 25 43 1 0 0 0 0 26 27 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 27 30 1 0 0 0 0 27 46 1 0 0 0 0 27 47 1 0 0 0 0 28 30 1 0 0 0 0 28 29 1 0 0 0 0 28 48 1 0 0 0 0 28 49 1 0 0 0 0 29 50 1 0 0 0 0 29 51 1 0 0 0 0 30 31 1 0 0 0 0 31 52 1 0 0 0 0 31 53 1 0 0 0 0 31 54 1 0 0 0 0 M END > (534) 533 > (534) C22H24BrFN4O2 > (534) 475.3596 > (534) FGFR-P533 > (534) ZD6474 > (534) FGFR-1 Tyrosine Kinase > (534) 3600 > (534) BINDDB > (534) <2007 > (534) P > (534) TRAIN $$$$ 1,6-naphthyridin 41 csChFnd70/04170815452D 77 80 0 0 0 0 0 0 0 0999 V2000 1.2227 17.9638 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 15.3545 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3129 16.1589 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7816 18.8982 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3768 17.9774 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8076 20.7210 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9355 20.5390 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4043 21.5413 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2459 16.2613 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8822 18.8331 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5052 23.4609 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6352 26.2167 -1.1650 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5379 24.4233 -1.1759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5620 24.3069 1.2039 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6533 26.1006 1.2080 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6943 27.0545 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5321 21.3701 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0056 20.4314 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9368 18.8567 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5553 21.2381 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1958 19.0820 -1.7108 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7195 21.4397 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1570 20.2177 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2287 19.0657 1.5281 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6921 27.1564 -2.3192 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8546 28.9998 -2.2350 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6832 26.9267 2.3747 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7156 28.7776 2.3058 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6344 13.5541 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2361 12.5335 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7886 10.6011 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4611 9.5352 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5219 6.6145 -0.1018 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0432 7.7303 -0.0815 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9323 4.7519 -0.1068 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6693 3.8911 1.4428 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1284 2.1825 1.4382 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8499 1.3350 -0.1162 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1118 2.1963 -1.6658 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6473 3.9065 -1.6611 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 18.6455 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4916 15.4033 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6180 21.4590 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7135 23.7718 -2.1015 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3087 23.5650 2.1274 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7678 28.4527 0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5869 22.6263 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6102 22.4945 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1449 19.9028 -2.8600 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3876 18.3229 -1.7267 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0829 18.2115 -1.7039 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6919 22.2487 1.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9111 20.6805 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6684 22.2605 -1.2438 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1157 18.1950 1.5350 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4204 18.3064 1.5122 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2010 19.8746 2.6863 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2013 29.3648 -2.4588 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0360 29.5904 -3.2239 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4504 29.4506 -0.9581 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1720 29.1939 1.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4133 29.2801 2.5262 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5860 29.2712 3.3036 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5191 12.9737 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9804 12.8487 -1.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0021 12.8354 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0441 10.2859 1.1055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0226 10.2990 -1.2019 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2056 9.8503 -1.2341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2273 9.8372 1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2883 6.8691 -1.2613 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3100 6.8560 1.0460 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8870 4.5532 2.6571 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9238 1.5097 2.6488 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4282 0.0000 -0.1198 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8946 1.5341 -2.8801 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8471 4.5809 -2.8717 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 41 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 42 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 43 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 44 1 0 0 0 0 14 15 1 0 0 0 0 14 45 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 46 1 0 0 0 0 17 18 1 0 0 0 0 17 47 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 48 1 0 0 0 0 21 23 1 0 0 0 0 21 49 1 0 0 0 0 21 50 1 0 0 0 0 21 51 1 0 0 0 0 22 23 1 0 0 0 0 22 52 1 0 0 0 0 22 53 1 0 0 0 0 22 54 1 0 0 0 0 23 24 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 24 57 1 0 0 0 0 25 26 1 0 0 0 0 26 58 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 27 28 1 0 0 0 0 28 61 1 0 0 0 0 28 62 1 0 0 0 0 28 63 1 0 0 0 0 29 30 1 0 0 0 0 29 64 1 0 0 0 0 30 31 1 0 0 0 0 30 65 1 0 0 0 0 30 66 1 0 0 0 0 31 32 1 0 0 0 0 31 67 1 0 0 0 0 31 68 1 0 0 0 0 32 34 1 0 0 0 0 32 69 1 0 0 0 0 32 70 1 0 0 0 0 33 34 1 0 0 0 0 33 35 1 0 0 0 0 33 71 1 0 0 0 0 33 72 1 0 0 0 0 35 40 1 0 0 0 0 35 36 2 0 0 0 0 36 37 1 0 0 0 0 36 73 1 0 0 0 0 37 38 2 0 0 0 0 37 74 1 0 0 0 0 38 39 1 0 0 0 0 38 75 1 0 0 0 0 39 40 2 0 0 0 0 39 76 1 0 0 0 0 40 77 1 0 0 0 0 M END > (56) 54 > (56) C31H37N5O4 > (56) 543.6644 > (56) FGFR-P54 > (56) 1,6-naphthyridine 41 > (56) FGFR-1 Tyrosine Kinase > (56) 910 > (56) BINDDB > (56) <2007 > (56) P > (56) TRAIN $$$$ 1,6-naphthyridin 42 csChFnd70/04170815452D 80 83 0 0 0 0 0 0 0 0999 V2000 1.2228 16.4431 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7135 13.8338 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3130 14.6383 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7817 17.3776 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3769 16.4568 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8077 19.2004 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9355 19.0184 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4044 20.0208 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 14.7407 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8822 17.3125 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5052 21.9405 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6353 24.6962 -1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5380 22.9028 -1.1760 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5620 22.7864 1.2040 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6533 24.5801 1.2080 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6944 25.5339 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5321 19.8495 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0056 18.9108 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9368 17.3361 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5554 19.7176 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1959 17.5614 -1.7107 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7196 19.9191 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1571 18.6972 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2288 17.5451 1.5281 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6922 25.6358 -2.3192 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8546 27.4794 -2.2350 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6833 25.4061 2.3747 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7157 27.2572 2.3059 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6345 12.0335 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2361 11.0129 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7886 9.0804 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4612 8.0145 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0137 6.0821 -0.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5761 5.0865 -0.1023 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3019 3.2544 -0.1102 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0271 2.3379 -0.1316 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3829 1.0790 -1.7128 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1925 0.6569 -0.1707 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4156 1.0678 1.3909 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8328 1.9086 1.4105 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8003 1.9197 -1.6932 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.1249 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4916 13.8827 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6179 19.9385 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7136 22.2512 -2.1016 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3087 22.0446 2.1275 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7679 26.9322 0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5870 21.1057 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6104 20.9739 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1450 18.3822 -2.8601 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3877 16.8022 -1.7267 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0830 16.6909 -1.7039 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6919 20.7281 1.0636 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9113 19.1600 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6685 20.7399 -1.2438 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1158 16.6744 1.5349 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4205 16.7858 1.5121 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2011 18.3541 2.6864 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0361 28.0699 -3.2240 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4504 27.9300 -0.9582 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2013 27.8442 -2.4588 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5861 27.7506 3.3037 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1721 27.6734 1.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4133 27.7596 2.5263 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5190 11.4531 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9805 11.3281 -1.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0021 11.3149 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0442 8.7653 1.1056 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0227 8.7784 -1.2019 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2056 8.3297 -1.2342 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2273 8.3166 1.0732 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2693 5.7669 1.0770 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2478 5.7801 -1.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5841 2.8806 1.0483 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5624 2.8937 -1.2592 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9900 0.7579 -2.9331 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4289 0.0000 -0.1862 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0479 0.7380 2.5957 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2262 2.2306 2.6308 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1679 2.2495 -2.8981 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 42 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 43 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 44 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 45 1 0 0 0 0 14 15 1 0 0 0 0 14 46 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 47 1 0 0 0 0 17 18 1 0 0 0 0 17 48 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 49 1 0 0 0 0 21 23 1 0 0 0 0 21 50 1 0 0 0 0 21 51 1 0 0 0 0 21 52 1 0 0 0 0 22 23 1 0 0 0 0 22 53 1 0 0 0 0 22 54 1 0 0 0 0 22 55 1 0 0 0 0 23 24 1 0 0 0 0 24 56 1 0 0 0 0 24 57 1 0 0 0 0 24 58 1 0 0 0 0 25 26 1 0 0 0 0 26 59 1 0 0 0 0 26 60 1 0 0 0 0 26 61 1 0 0 0 0 27 28 1 0 0 0 0 28 62 1 0 0 0 0 28 63 1 0 0 0 0 28 64 1 0 0 0 0 29 30 1 0 0 0 0 29 65 1 0 0 0 0 30 31 1 0 0 0 0 30 66 1 0 0 0 0 30 67 1 0 0 0 0 31 32 1 0 0 0 0 31 68 1 0 0 0 0 31 69 1 0 0 0 0 32 33 1 0 0 0 0 32 70 1 0 0 0 0 32 71 1 0 0 0 0 33 34 1 0 0 0 0 33 72 1 0 0 0 0 33 73 1 0 0 0 0 34 35 1 0 0 0 0 35 36 1 0 0 0 0 35 74 1 0 0 0 0 35 75 1 0 0 0 0 36 40 2 0 0 0 0 36 41 1 0 0 0 0 37 38 1 0 0 0 0 37 41 2 0 0 0 0 37 76 1 0 0 0 0 38 39 2 0 0 0 0 38 77 1 0 0 0 0 39 40 1 0 0 0 0 39 78 1 0 0 0 0 40 79 1 0 0 0 0 41 80 1 0 0 0 0 M END > (57) 55 > (57) C32H39N5O4 > (57) 557.6912 > (57) FGFR-P55 > (57) 1,6-naphthyridine 42 > (57) FGFR-1 Tyrosine Kinase > (57) 1100 > (57) BINDDB > (57) <2007 > (57) P > (57) TRAIN $$$$ 1,6-naphthyridin 43 csChFnd70/04170815452D 83 86 0 0 0 0 0 0 0 0999 V2000 1.2228 20.9615 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 18.3523 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3129 19.1568 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7816 21.8960 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3768 20.9751 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8076 23.7187 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9353 23.5367 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4043 24.5391 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 19.2591 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8821 21.8309 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5051 26.4586 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6352 29.2144 -1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5379 27.4210 -1.1760 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5618 27.3045 1.2040 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6532 29.0982 1.2080 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6943 30.0521 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5318 24.3678 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0053 23.4291 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9365 21.8545 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5550 24.2358 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1955 22.0798 -1.7107 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7192 24.4374 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1567 23.2154 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2284 22.0635 1.5281 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6921 30.1540 -2.3191 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8545 31.9974 -2.2350 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6830 29.9243 2.3746 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7154 31.7753 2.3058 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6344 16.5521 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2360 15.5315 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7885 13.5991 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4611 12.5332 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0136 10.6008 -0.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6861 9.5349 -0.1037 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2682 7.7302 -0.1101 O 0 0 0 0 0 0 0 0 0 0 0 0 7.7469 6.6144 -0.1303 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1572 4.7519 -0.1355 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8943 3.8910 1.4142 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3535 2.1826 1.4096 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0749 1.3352 -0.1447 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3368 2.1964 -1.6944 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8722 3.9066 -1.6896 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 21.6433 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4915 18.4011 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6179 24.4567 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7135 26.7695 -2.1015 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3085 26.5627 2.1274 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7678 31.4503 0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5867 25.6240 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6100 25.4922 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1446 22.9006 -2.8600 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3873 21.3206 -1.7267 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0826 21.2093 -1.7039 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6915 25.2464 1.0636 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9108 23.6783 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6681 25.2582 -1.2438 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1154 21.1928 1.5349 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4201 21.3042 1.5121 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2007 22.8724 2.6863 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2012 32.3622 -2.4587 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0360 32.5880 -3.2239 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4503 32.4481 -0.9582 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5858 32.2687 3.3036 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1718 32.1914 1.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4131 32.2777 2.5262 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5190 15.9717 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9804 15.8467 -1.2057 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0020 15.8335 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0441 13.2840 1.1056 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0226 13.2971 -1.2019 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2054 12.8484 -1.2342 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2271 12.8353 1.0732 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2692 10.2857 1.0770 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2477 10.2989 -1.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4305 9.8502 -1.2627 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4521 9.8370 1.0446 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5132 6.8690 -1.2899 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5349 6.8558 1.0175 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1118 4.5532 2.6286 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1489 1.5098 2.6203 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6532 0.0000 -0.1484 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1196 1.5340 -2.9087 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0721 4.5808 -2.9003 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 43 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 44 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 45 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 46 1 0 0 0 0 14 15 1 0 0 0 0 14 47 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 48 1 0 0 0 0 17 18 1 0 0 0 0 17 49 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 50 1 0 0 0 0 21 23 1 0 0 0 0 21 51 1 0 0 0 0 21 52 1 0 0 0 0 21 53 1 0 0 0 0 22 23 1 0 0 0 0 22 54 1 0 0 0 0 22 55 1 0 0 0 0 22 56 1 0 0 0 0 23 24 1 0 0 0 0 24 57 1 0 0 0 0 24 58 1 0 0 0 0 24 59 1 0 0 0 0 25 26 1 0 0 0 0 26 60 1 0 0 0 0 26 61 1 0 0 0 0 26 62 1 0 0 0 0 27 28 1 0 0 0 0 28 63 1 0 0 0 0 28 64 1 0 0 0 0 28 65 1 0 0 0 0 29 30 1 0 0 0 0 29 66 1 0 0 0 0 30 31 1 0 0 0 0 30 67 1 0 0 0 0 30 68 1 0 0 0 0 31 32 1 0 0 0 0 31 69 1 0 0 0 0 31 70 1 0 0 0 0 32 33 1 0 0 0 0 32 71 1 0 0 0 0 32 72 1 0 0 0 0 33 34 1 0 0 0 0 33 73 1 0 0 0 0 33 74 1 0 0 0 0 34 35 1 0 0 0 0 34 75 1 0 0 0 0 34 76 1 0 0 0 0 35 36 1 0 0 0 0 36 37 1 0 0 0 0 36 77 1 0 0 0 0 36 78 1 0 0 0 0 37 42 1 0 0 0 0 37 38 2 0 0 0 0 38 39 1 0 0 0 0 38 79 1 0 0 0 0 39 40 2 0 0 0 0 39 80 1 0 0 0 0 40 41 1 0 0 0 0 40 81 1 0 0 0 0 41 42 2 0 0 0 0 41 82 1 0 0 0 0 42 83 1 0 0 0 0 M END > (58) 56 > (58) C33H41N5O4 > (58) 571.718 > (58) FGFR-P56 > (58) 1,6-naphthyridine 43 > (58) FGFR-1 Tyrosine Kinase > (58) 3300 > (58) BINDDB > (58) <2007 > (58) P > (58) TRAIN $$$$ 1,6-naphthyridin 75 csChFnd70/04170815452D 64 66 0 0 0 0 0 0 0 0999 V2000 1.2227 10.9873 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7131 8.3782 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3125 9.1826 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7813 11.9216 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3764 11.0008 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8073 13.7442 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9349 13.5622 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4039 14.5645 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 9.2850 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8816 11.8565 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5047 16.4839 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6349 19.2394 -1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5375 17.4461 -1.1759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5615 17.3297 1.2039 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6527 19.1233 1.2079 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6938 20.0771 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5312 14.3933 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0046 13.4546 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9358 11.8801 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5542 14.2613 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1945 12.1054 -1.7106 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7180 14.4629 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1557 13.2410 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2274 12.0891 1.5280 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6918 20.1790 -2.3189 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8542 22.0222 -2.2347 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6824 19.9493 2.3743 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7148 21.8000 2.3055 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6341 6.5781 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2356 5.5577 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7881 3.6254 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4606 2.5596 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0427 0.7550 -0.0815 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.6689 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4911 8.4271 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6178 14.4822 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7132 16.7947 -2.1013 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3080 16.5879 2.1272 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7673 21.4751 0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5861 15.6493 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6092 15.5175 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1435 12.9261 -2.8597 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3862 11.3464 -1.7266 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0816 11.2350 -1.7037 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6904 15.2718 1.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9096 13.7038 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6669 15.2836 -1.2437 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1144 11.2185 1.5348 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4190 11.3298 1.5120 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1997 12.8980 2.6860 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4501 22.4728 -0.9581 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2008 22.3870 -2.4585 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0358 22.6127 -3.2236 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1712 22.2162 1.0347 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4128 22.3024 2.5259 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5852 22.2934 3.3033 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5189 5.9978 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9799 5.8728 -1.2056 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0016 5.8596 1.1017 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0438 3.3103 1.1055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0222 3.3234 -1.2018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2049 2.8747 -1.2341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2266 2.8616 1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0433 0.0000 -0.0953 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 34 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 35 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 36 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 37 1 0 0 0 0 14 15 1 0 0 0 0 14 38 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 39 1 0 0 0 0 17 18 1 0 0 0 0 17 40 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 41 1 0 0 0 0 21 23 1 0 0 0 0 21 42 1 0 0 0 0 21 43 1 0 0 0 0 21 44 1 0 0 0 0 22 23 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 23 24 1 0 0 0 0 24 48 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 25 26 1 0 0 0 0 26 51 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 27 28 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 29 30 1 0 0 0 0 29 57 1 0 0 0 0 30 31 1 0 0 0 0 30 58 1 0 0 0 0 30 59 1 0 0 0 0 31 32 1 0 0 0 0 31 60 1 0 0 0 0 31 61 1 0 0 0 0 32 33 1 0 0 0 0 32 62 1 0 0 0 0 32 63 1 0 0 0 0 33 64 1 0 0 0 0 M END > (62) 60 > (62) C24H31N5O4 > (62) 453.54 > (62) FGFR-P60 > (62) 1,6-naphthyridine 75 > (62) FGFR-1 Tyrosine Kinase > (62) 49 > (62) BINDDB > (62) <2007 > (62) P > (62) TRAIN $$$$ 1,6-naphthyridin 76 csChFnd70/04170815452D 67 69 0 0 0 0 0 0 0 0999 V2000 1.2227 12.5955 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7133 9.9863 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3127 10.7907 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7815 13.5299 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3765 12.6091 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8075 15.3525 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9351 15.1705 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4040 16.1728 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 10.8931 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8818 13.4648 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5049 18.0923 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6351 20.8480 -1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5377 19.0546 -1.1759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5616 18.9382 1.2039 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6529 20.7318 1.2079 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6940 21.6857 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5316 16.0016 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0050 15.0630 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9362 13.4884 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5547 15.8696 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1951 13.7137 -1.7107 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7187 16.0712 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1563 14.8492 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2280 13.6974 1.5280 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6920 21.7876 -2.3190 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8544 23.6310 -2.2349 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6827 21.5579 2.3745 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7151 23.4088 2.3057 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6343 8.1861 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2358 7.1656 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7883 5.2333 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4608 4.1675 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0133 2.2352 -0.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5755 1.2397 -0.1023 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 13.2773 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4912 10.0352 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6178 16.0905 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 18.4032 -2.1014 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3082 18.1964 2.1273 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7675 23.0838 0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5864 17.2577 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6096 17.1259 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1441 14.5344 -2.8599 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3868 12.9546 -1.7266 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0822 12.8432 -1.7038 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6910 16.8801 1.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9102 15.3120 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6676 16.8919 -1.2437 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1149 12.8268 1.5349 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4196 12.9381 1.5121 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2003 14.5062 2.6862 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4502 24.0816 -0.9581 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2011 23.9958 -2.4587 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0359 24.2214 -3.2238 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4129 23.9111 2.5261 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5855 23.9022 3.3035 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1716 23.8249 1.0347 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5189 7.6057 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9801 7.4808 -1.2056 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0017 7.4675 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0440 4.9181 1.1055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0224 4.9313 -1.2018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2051 4.4827 -1.2341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2268 4.4695 1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2690 1.9200 1.0770 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2474 1.9332 -1.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3900 0.0000 -0.1076 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 35 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 36 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 37 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 38 1 0 0 0 0 14 15 1 0 0 0 0 14 39 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 40 1 0 0 0 0 17 18 1 0 0 0 0 17 41 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 42 1 0 0 0 0 21 23 1 0 0 0 0 21 43 1 0 0 0 0 21 44 1 0 0 0 0 21 45 1 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 22 48 1 0 0 0 0 23 24 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 25 26 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 26 54 1 0 0 0 0 27 28 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 28 57 1 0 0 0 0 29 30 1 0 0 0 0 29 58 1 0 0 0 0 30 31 1 0 0 0 0 30 59 1 0 0 0 0 30 60 1 0 0 0 0 31 32 1 0 0 0 0 31 61 1 0 0 0 0 31 62 1 0 0 0 0 32 33 1 0 0 0 0 32 63 1 0 0 0 0 32 64 1 0 0 0 0 33 34 1 0 0 0 0 33 65 1 0 0 0 0 33 66 1 0 0 0 0 34 67 1 0 0 0 0 M END > (63) 61 > (63) C25H33N5O4 > (63) 467.5668 > (63) FGFR-P61 > (63) 1,6-naphthyridine 76 > (63) FGFR-1 Tyrosine Kinase > (63) 52 > (63) BINDDB > (63) <2007 > (63) P > (63) TRAIN $$$$ 1,6-naphthyridin 77 csChFnd70/04170815452D 70 72 0 0 0 0 0 0 0 0999 V2000 1.2227 13.9857 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7132 11.3766 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3126 12.1810 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7814 14.9202 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3765 13.9994 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8075 16.7427 0.0110 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9351 16.5607 -0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4040 17.5631 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2458 12.2834 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8818 14.8551 -0.0284 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5049 19.4826 0.0078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6350 22.2382 -1.1649 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5376 20.4449 -1.1759 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5616 20.3284 1.2039 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6529 22.1221 1.2079 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6940 23.0759 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5316 17.3918 -0.0323 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0050 16.4531 -0.0520 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9362 14.8787 -0.0592 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5546 17.2598 -0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1950 15.1040 -1.7107 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7186 17.4614 -0.0946 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1562 16.2395 -0.0850 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2279 15.0876 1.5280 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6920 23.1778 -2.3190 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8544 25.0211 -2.2349 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6827 22.9481 2.3745 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7151 24.7989 2.3057 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6343 9.5764 -0.0258 N 0 0 3 0 0 0 0 0 0 0 0 0 4.2357 8.5560 -0.0467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7882 6.6236 -0.0534 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4608 5.5577 -0.0752 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0133 3.6254 -0.0820 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6858 2.5596 -0.1037 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2679 0.7550 -0.1101 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.6675 0.0332 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4912 11.4255 -0.0421 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6178 17.4807 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7134 19.7934 -2.1014 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3082 19.5867 2.1273 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7675 24.4739 0.0288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5864 18.6480 -0.0264 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6095 18.5161 -0.0578 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1440 15.9247 -2.8599 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3867 14.3448 -1.7266 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0821 14.2335 -1.7038 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6909 18.2703 1.0635 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9102 16.7024 -0.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 13.6675 18.2821 -1.2437 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1148 14.2170 1.5349 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4195 14.3284 1.5121 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2002 15.8966 2.6862 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0359 25.6116 -3.2238 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4502 25.4717 -0.9581 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2010 25.3859 -2.4587 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1716 25.2151 1.0347 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4129 25.3013 2.5261 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5855 25.2923 3.3035 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5189 8.9961 -0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9801 8.8711 -1.2056 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0017 8.8579 1.1018 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0440 6.3085 1.1055 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0224 6.3216 -1.2018 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2051 5.8729 -1.2341 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2268 5.8598 1.0731 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2689 3.3104 1.0770 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2474 3.3235 -1.2304 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4302 2.8748 -1.2626 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4518 2.8616 1.0446 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2685 0.0000 -0.1238 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 4 2 0 0 0 0 1 36 1 0 0 0 0 2 9 2 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 5 2 0 0 0 0 3 37 1 0 0 0 0 4 6 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 6 8 2 0 0 0 0 6 38 1 0 0 0 0 7 10 2 0 0 0 0 7 8 1 0 0 0 0 7 17 1 0 0 0 0 8 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 25 1 0 0 0 0 13 39 1 0 0 0 0 14 15 1 0 0 0 0 14 40 1 0 0 0 0 15 16 2 0 0 0 0 15 27 1 0 0 0 0 16 41 1 0 0 0 0 17 18 1 0 0 0 0 17 42 1 0 0 0 0 18 19 2 0 0 0 0 18 20 1 0 0 0 0 20 23 1 0 0 0 0 20 43 1 0 0 0 0 21 23 1 0 0 0 0 21 44 1 0 0 0 0 21 45 1 0 0 0 0 21 46 1 0 0 0 0 22 23 1 0 0 0 0 22 47 1 0 0 0 0 22 48 1 0 0 0 0 22 49 1 0 0 0 0 23 24 1 0 0 0 0 24 50 1 0 0 0 0 24 51 1 0 0 0 0 24 52 1 0 0 0 0 25 26 1 0 0 0 0 26 53 1 0 0 0 0 26 54 1 0 0 0 0 26 55 1 0 0 0 0 27 28 1 0 0 0 0 28 56 1 0 0 0 0 28 57 1 0 0 0 0 28 58 1 0 0 0 0 29 30 1 0 0 0 0 29 59 1 0 0 0 0 30 31 1 0 0 0 0 30 60 1 0 0 0 0 30 61 1 0 0 0 0 31 32 1 0 0 0 0 31 62 1 0 0 0 0 31 63 1 0 0 0 0 32 33 1 0 0 0 0 32 64 1 0 0 0 0 32 65 1 0 0 0 0 33 34 1 0 0 0 0 33 66 1 0 0 0 0 33 67 1 0 0 0 0 34 35 1 0 0 0 0 34 68 1 0 0 0 0 34 69 1 0 0 0 0 35 70 1 0 0 0 0 M END > (64) 62 > (64) C26H35N5O4 > (64) 481.5936 > (64) FGFR-P62 > (64) 1,6-naphthyridine 77 > (64) FGFR-1 Tyrosine Kinase > (64) 93 > (64) BINDDB > (64) <2007 > (64) P > (64) TRAIN $$$$ 1,6-naphthyridine-2,7-diamine deriv. 20 csChFnd70/04170815452D 76 79 0 0 0 0 0 0 0 0999 V2000 2.7488 16.6870 0.0127 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8809 16.5923 -0.0178 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3221 17.5516 0.0022 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3941 13.9882 -0.0175 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7736 14.8639 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2416 13.8859 0.0114 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8051 11.3194 -0.0179 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3814 12.1684 -0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3126 12.1848 0.0010 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8752 14.8857 -0.0268 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3693 19.4734 0.0115 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4548 22.1433 1.2037 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4588 23.0710 0.0280 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4132 20.3476 1.1989 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3759 20.4091 -1.1722 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4236 22.2045 -1.1604 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4544 23.1182 -2.3140 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5657 24.9656 -2.2292 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4724 22.9970 2.3613 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4527 24.8483 2.2938 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7767 9.5175 -0.0279 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4537 17.4678 -0.0287 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9530 16.5705 -0.0484 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9283 14.9945 -0.0567 O 0 0 0 0 0 0 0 0 0 0 0 0 10.4797 17.4204 -0.0590 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1095 16.4449 -0.0804 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1805 15.3119 -1.7070 C 0 0 0 0 0 0 0 0 0 0 0 0 13.6373 17.7102 -0.0888 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2127 15.2944 1.5321 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4064 8.5421 -0.0487 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0135 6.5977 -0.0561 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7154 5.5793 -0.0779 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0112 3.2789 1.2129 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6025 1.3393 1.1086 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4851 0.7602 0.1090 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9232 2.6940 0.2034 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3381 3.7124 -0.0850 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1649 0.3709 1.3514 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5390 17.3914 0.0337 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.5332 0.0272 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5811 11.4465 -0.0427 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4933 24.4708 0.0347 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1885 19.6261 2.1148 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5699 19.7354 -2.0980 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1495 25.4045 -0.9520 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9018 25.3678 -2.4531 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7308 25.5337 -3.2178 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8855 25.2778 1.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1391 25.3142 2.5270 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3185 25.3651 3.2838 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6779 8.9059 -0.0211 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4736 18.7252 -0.0222 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4996 18.6779 -0.0525 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1070 16.1315 -2.8558 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3930 14.5862 -1.7229 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0921 14.4103 -1.7010 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5866 18.5176 1.0700 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8498 16.9846 -0.1048 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5636 18.5301 -1.2377 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1243 14.3931 1.5381 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4253 14.5687 1.5162 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1621 16.1016 2.6909 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1420 8.8785 -1.2077 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1636 8.8653 1.1000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2780 6.2614 1.1028 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2563 6.2747 -1.2049 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4509 5.9156 -1.2368 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4725 5.9023 1.0707 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8377 4.0229 0.9550 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4943 3.5904 2.5039 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6739 0.9978 2.1176 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0541 1.0402 -0.1592 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0207 0.4444 -1.1878 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6415 0.0000 0.3953 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4528 2.9963 1.4782 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8754 3.0112 -0.7915 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 3 2 0 0 0 0 1 39 1 0 0 0 0 2 10 2 0 0 0 0 2 3 1 0 0 0 0 2 22 1 0 0 0 0 3 11 1 0 0 0 0 4 10 1 0 0 0 0 4 8 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 6 40 1 0 0 0 0 7 9 2 0 0 0 0 7 8 1 0 0 0 0 7 21 1 0 0 0 0 8 41 1 0 0 0 0 11 15 1 0 0 0 0 11 14 2 0 0 0 0 12 14 1 0 0 0 0 12 13 2 0 0 0 0 12 19 1 0 0 0 0 13 16 1 0 0 0 0 13 42 1 0 0 0 0 14 43 1 0 0 0 0 15 16 2 0 0 0 0 15 44 1 0 0 0 0 16 17 1 0 0 0 0 17 18 1 0 0 0 0 18 45 1 0 0 0 0 18 46 1 0 0 0 0 18 47 1 0 0 0 0 19 20 1 0 0 0 0 20 48 1 0 0 0 0 20 49 1 0 0 0 0 20 50 1 0 0 0 0 21 30 1 0 0 0 0 21 51 1 0 0 0 0 22 23 1 0 0 0 0 22 52 1 0 0 0 0 23 24 2 0 0 0 0 23 25 1 0 0 0 0 25 26 1 0 0 0 0 25 53 1 0 0 0 0 26 27 1 0 0 0 0 26 28 1 0 0 0 0 26 29 1 0 0 0 0 27 54 1 0 0 0 0 27 55 1 0 0 0 0 27 56 1 0 0 0 0 28 57 1 0 0 0 0 28 58 1 0 0 0 0 28 59 1 0 0 0 0 29 60 1 0 0 0 0 29 61 1 0 0 0 0 29 62 1 0 0 0 0 30 31 1 0 0 0 0 30 63 1 0 0 0 0 30 64 1 0 0 0 0 31 32 1 0 0 0 0 31 65 1 0 0 0 0 31 66 1 0 0 0 0 32 37 1 0 0 0 0 32 67 1 0 0 0 0 32 68 1 0 0 0 0 33 37 1 0 0 0 0 33 34 1 0 0 0 0 33 69 1 0 0 0 0 33 70 1 0 0 0 0 34 38 1 0 0 0 0 34 71 1 0 0 0 0 34 72 1 0 0 0 0 35 38 1 0 0 0 0 35 36 1 0 0 0 0 35 73 1 0 0 0 0 35 74 1 0 0 0 0 36 37 1 0 0 0 0 36 75 1 0 0 0 0 36 76 1 0 0 0 0 M END > (75) 73 > (75) C28H38N6O4 > (75) 522.646 > (75) FGFR-P73 > (75) 1,6-naphthyridine deriv. 20 > (75) FGFR-1 Tyrosine Kinase > (75) 31 > (75) BINDDB > (75) <2007 > (75) P > (75) TRAIN $$$$ 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c csChFnd70/04170815452D 42 44 0 0 0 0 0 0 0 0999 V2000 6.0868 10.8488 0.6168 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3128 8.3699 0.1557 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8247 9.1736 0.5176 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8546 12.0852 0.9744 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7962 11.1445 0.3105 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5485 9.5199 0.0183 N 0 0 0 0 0 0 0 0 0 0 0 0 8.6024 12.6874 0.2921 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8157 13.9888 0.6820 O 0 0 0 0 0 0 0 0 0 0 0 0 10.4379 12.7964 -0.2011 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9001 13.1806 -1.9064 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6248 13.2808 -2.3570 C 0 0 0 0 0 0 0 0 0 0 0 0 13.8920 13.0022 -1.1291 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4471 12.6218 0.5593 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7296 12.5236 1.0348 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5162 6.5926 -0.0434 N 0 0 3 0 0 0 0 0 0 0 0 0 6.0928 5.4963 0.1305 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4609 6.0561 -0.3634 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0570 4.9694 -0.1898 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2742 3.3256 0.4752 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8966 2.7643 0.9680 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3075 3.8414 0.7905 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3022 0.8395 -1.1276 N 0 0 0 0 0 0 0 0 0 0 0 0 1.9185 0.7272 1.9982 O 0 0 0 0 0 0 0 0 0 0 0 0 1.4790 1.9439 0.6958 S 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.0268 0.7914 O 0 0 0 0 0 0 0 0 0 0 0 0 9.6642 13.4521 -3.1082 F 0 0 0 0 0 0 0 0 0 0 0 0 11.2981 12.1591 2.6860 F 0 0 0 0 0 0 0 0 0 0 0 0 13.1257 13.6943 -4.1920 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6665 11.7446 1.1800 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1763 13.2954 1.0202 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2370 13.0818 -1.4905 H 0 0 0 0 0 0 0 0 0 0 0 0 14.4453 12.4057 1.5097 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6458 6.1164 -0.3025 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2903 7.3400 -0.8819 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7880 5.4038 -0.5734 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0616 1.4801 1.4873 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5753 3.4001 1.1703 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1186 1.0322 -2.0584 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3822 0.0000 -1.2649 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2476 15.0890 -4.3423 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3569 13.0806 -4.4921 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1352 13.2126 -5.0689 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 5 1 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 6 2 0 0 0 0 2 15 1 0 0 0 0 4 29 1 0 0 0 0 4 30 1 0 0 0 0 5 6 1 0 0 0 0 5 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 9 14 1 0 0 0 0 9 10 2 0 0 0 0 10 11 1 0 0 0 0 10 26 1 0 0 0 0 11 12 2 0 0 0 0 11 28 1 0 0 0 0 12 13 1 0 0 0 0 12 31 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 27 1 0 0 0 0 15 16 1 0 0 0 0 15 33 1 0 0 0 0 16 21 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 17 34 1 0 0 0 0 18 19 2 0 0 0 0 18 35 1 0 0 0 0 19 20 1 0 0 0 0 19 24 1 0 0 0 0 20 21 2 0 0 0 0 20 36 1 0 0 0 0 21 37 1 0 0 0 0 22 24 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 2 0 0 0 0 24 25 2 0 0 0 0 28 40 1 0 0 0 0 28 41 1 0 0 0 0 28 42 1 0 0 0 0 M END > (86) 84 > (86) C16H14F2N6O3S > (86) 408.3818 > (86) FGFR-P84 > (86) 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c > (86) FGFR-2 Tyrosine Kinase > (86) 270 > (86) BINDDB > (86) <2007 > (86) P > (86) TRAIN $$$$ 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f csChFnd70/04170815452D 39 41 0 0 0 0 0 0 0 0999 V2000 4.0383 10.1642 -0.2089 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4688 8.2251 -0.1460 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0681 8.7131 -0.0451 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7904 11.0527 -0.1654 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4612 10.6344 -0.4228 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3552 9.3572 -0.3761 N 0 0 0 0 0 0 0 0 0 0 0 0 5.9186 12.0434 -0.6373 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0185 13.0510 -0.6531 O 0 0 0 0 0 0 0 0 0 0 0 0 5.9144 6.7479 -0.0251 N 0 0 3 0 0 0 0 0 0 0 0 0 4.8511 5.6240 0.0964 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4622 5.8002 -0.5521 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4140 4.6874 -0.4303 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7455 3.3984 0.3362 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1268 3.2193 0.9836 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1824 4.3253 0.8606 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6318 0.8595 -0.9510 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7861 1.1432 1.7707 O 0 0 0 0 0 0 0 0 0 0 0 0 1.4050 1.9810 0.4889 S 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.6740 0.2971 O 0 0 0 0 0 0 0 0 0 0 0 0 7.4983 12.3613 -0.8511 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2394 12.3712 -1.1558 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6141 13.7173 -1.2447 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0974 13.7392 -1.0778 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9314 11.0348 -0.8495 S 0 0 0 0 0 0 0 0 0 0 0 0 7.1850 15.1409 -1.1384 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8210 10.6122 -0.0016 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8826 12.1177 -0.2985 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9628 6.4996 -0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2023 6.8068 -1.1505 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3340 4.8238 -0.9338 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3819 2.2116 1.5821 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2627 4.1826 1.3619 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4031 1.0622 -1.6753 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9935 0.0000 -1.0701 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4152 12.1596 -1.2624 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2549 14.7132 -1.4352 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0908 15.6095 -0.0261 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7234 15.9416 -1.8693 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0806 14.8854 -1.5634 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 5 1 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 6 2 0 0 0 0 2 9 1 0 0 0 0 4 26 1 0 0 0 0 4 27 1 0 0 0 0 5 6 1 0 0 0 0 5 7 1 0 0 0 0 7 8 2 0 0 0 0 7 20 1 0 0 0 0 9 10 1 0 0 0 0 9 28 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 11 29 1 0 0 0 0 12 13 2 0 0 0 0 12 30 1 0 0 0 0 13 14 1 0 0 0 0 13 18 1 0 0 0 0 14 15 2 0 0 0 0 14 31 1 0 0 0 0 15 32 1 0 0 0 0 16 18 1 0 0 0 0 16 33 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 18 19 2 0 0 0 0 20 23 2 0 0 0 0 20 24 1 0 0 0 0 21 22 2 0 0 0 0 21 24 1 0 0 0 0 21 35 1 0 0 0 0 22 23 1 0 0 0 0 22 36 1 0 0 0 0 23 25 1 0 0 0 0 25 37 1 0 0 0 0 25 38 1 0 0 0 0 25 39 1 0 0 0 0 M END > (87) 85 > (87) C14H14N6O3S2 > (87) 378.423 > (87) FGFR-P85 > (87) 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f > (87) FGFR-2 Tyrosine Kinase > (87) 180 > (87) BINDDB > (87) <2007 > (87) P > (87) TRAIN $$$$