Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0L0LR
|
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| Former ID |
DIB015375
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| Drug Name |
UCL-67022
|
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| Synonyms |
HDAC inhibitor (multiple myeloma), ST Barts/UCL
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| Indication | Multiple myeloma [ICD9: 203; ICD10:C90] | Investigative | [1] | ||
| Company |
University College London
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c1cccc(c1)NC(=O)C(CCCCCC(=O)NO)C(=O)Nc1ccccc1
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| Target and Pathway | |||||
| Target(s) | Histone deacetylase 6 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Alcoholism | ||||
| Viral carcinogenesis | |||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | ||||
| Signaling events mediated by HDAC Class I | |||||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | ||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| Assembly of the primary cilium | |||||
| WikiPathways | Ectoderm Differentiation | ||||
| Neural Crest Differentiation | |||||
| Cell Cycle | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2618). | ||||
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