Target General Information
Target ID T86323 Target Info
Target Name Neural cell adhesion molecule 1 (NCAM1)
Synonyms NCAM-1; NCAM; N-CAM-1; MSK39; CD56
Target Type Clinical trial Target
Gene Name NCAM1
UniProt ID
Targeted Antigens of CAR-T Cell Therapy
CAR T-Cell Therapy Drug(s) CD56 CAR T cells Drug Info Phase 1/2 Multiple myeloma [1]
CD56-specific gene-engineered T cells Drug Info Phase 1/2 Acute myeloid leukaemia [2]
CART-56 cells Drug Info Phase 1 Myelodysplastic syndrome [3]
CAR-T cells targeting CD56 Drug Info Clinical trial Multiple myeloma [4]
CAR-T cells targeting CD56 Drug Info Preclinical Acute myeloid leukaemia [5]
References
REF 1 ClinicalTrials.gov (NCT03271632) Multi-CAR T Cell Therapy in the Treatment of Multiple Myeloma
REF 2 ClinicalTrials.gov (NCT03222674) Multi-CAR T Cell Therapy for Acute Myeloid Leukemia
REF 3 ClinicalTrials.gov (NCT03291444) CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS
REF 4 ClinicalTrials.gov (NCT03473496) CAR-T Cells Therapy in Relapsed/Refractory Multiple Myeloma
REF 5 ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia

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