Drug Information

Drug General Information
Drug ID
DX2DIO
Drug Name
(S)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-piperidin-3-one
Synonyms
CHEMBL20710
Indication Discovery agent Investigative [1587926]
Formula
C27H28FNO2
Canonical SMILES
Fc1ccc(CN2CC[C@@H](CCOC(c3ccccc3)c4ccccc4)C(=O)C2)cc1
InChI
InChI=1S/C27H28FNO2/c28-25-13-11-21(12-14-25)19-29-17-15-22(26(30)20-29)16-18-31-27(23-7-3-1-4-8-23)24-9-5-2-6-10-24/h1-14,22,27H,15-20H2/t22-/m0/s1
InChIKey
OXOCBMINRFJHLS-QFIPXVFZSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.