Drug Information

Drug General Information
Drug ID
DXT51Z
Drug Name
8-Methyl-2-(3-phenyl-[1,2,4]oxadiazol-5-yl)-3-p-tolyl-8-aza-bicyclo[3.2.1]octane
Synonyms
CHEMBL607051
Indication Discovery agent Investigative [1587926]
Formula
C23H25N3O
Canonical SMILES
CN1[C@@H]2CCC1C([C@H](C2)c3ccc(C)cc3)c4onc(n4)c5ccccc5
InChI
InChI=1S/C23H25N3O/c1-15-8-10-16(11-9-15)19-14-18-12-13-20(26(18)2)21(19)23-24-22(25-27-23)17-6-4-3-5-7-17/h3-11,18-21H,12-14H2,1-2H3/t18-,19-,20?,21?/m1/s1
InChIKey
WYJIEKRDCVWTRP-HJLBWTBNSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.