Drug General Information
Drug ID	D03QIE
Former ID	DCL000723
Drug Name	Bicifadine
Drug Type	Small molecular drug
Indication	Chronic low back pain; Neuropathic pain [ICD9: 338, 356.0, 356.8, 724.2, 724.5,780; ICD10:G64, G90.0, M54, M54.5, R52, G89]		Phase 3	[536374]
Therapeutic Class	Analgesics
Company	Dov Pharmaceutical
Structure		Download 2D MOL 3D MOL
Formula	C12H15N
Canonical SMILES	CC1=CC=C(C=C1)C23CC2CNC3
InChI	1S/C12H15N/c1-9-2-4-10(5-3-9)12-6-11(12)7-13-8-12/h2-5,11,13H,6-8H2,1H3
InChIKey	OFYVIGTWSQPCLF-UHFFFAOYSA-N
CAS Number	CAS 71195-57-8
PubChem Compound ID	47953
PubChem Substance ID	8180475, 12015676, 15147197, 33622062, 34712882, 57313166, 79431140, 103585713, 104354237, 126418129, 126684829, 128803524, 131324463, 132554357, 134339221, 134357076, 135047654, 136996475, 137006897, 139258240, 143493258, 152238496, 162121875, 163366968, 170495860, 175426892, 179150997, 223679616, 224051267, 226424261, 241117407, 249808189
SuperDrug ATC ID	L01XX22
SuperDrug CAS ID	cas=005300038
Target and Pathway
Target(s)	Sodium-dependent noradrenaline transporter	Target Info	Modulator
	Sodium-dependent serotonin transporter	Target Info	Modulator
KEGG Pathway	Serotonergic synapse
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathway
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
	SIDS Susceptibility Pathways
	Synaptic Vesicle Pathway
	Serotonin Transporter Activity
References
Ref 536374	Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.