You are searching for: hsa04510

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T20761 Target Info	Target Name	Vascular endothelial growth factor A (VEGFA)
	Target type	Successful Target
	Disease	Neovascular age-related macular degeneration; Wet age-related macular degeneration;
	Drugs	Faricimab	Drug Info

T30040 Target Info	Target Name	Vascular endothelial growth factor B (VEGFB)
	Target type	Successful Target
	Disease	Metastatic colorectal cancer; Diabetic kidney disease;
	Drugs	Aflibercept	Drug Info

T99057 Target Info	Target Name	HUMAN ERK activator kinase 1 (MEK1)
	Target type	. Target
	Disease	Metastatic melanoma; Neurofibromatosis type 1;
	Drugs	Trametinib	Drug Info

T82795 Target Info	Target Name	Beta-catenin (CTNNB1)
	Target type	Successful Target
	Disease	Solid tumour/cancer; Familial adenomatous polyposis;
	Drugs	Recombinant human endostatin	Drug Info

T33425 Target Info	Target Name	Epidermal growth factor (EGF)
	Target type	Successful Target
	Disease	Vulnerary; Wound healing;
	Drugs	Epidermal growth factor	Drug Info

T51282 Target Info	Target Name	Rho-associated protein kinase 1 (ROCK1)
	Target type	Successful Target
	Disease	Open-angle glaucoma; Diabetic nephropathy;
	Drugs	Netarsudil	Drug Info

T35940 Target Info	Target Name	ERK activator kinase 1 (MEK1)
	Target type	Clinical trial Target
	Disease	Melanoma; Thyroid cancer;
	Drugs	Selumetinib	Drug Info

T70977 Target Info	Target Name	Glycogen synthase kinase-3 beta (GSK-3B)
	Target type	Clinical trial Target
	Disease	Myotonic dystrophy; Acute myeloid leukaemia;
	Drugs	AMO-02	Drug Info

T67619 Target Info	Target Name	RAC-alpha serine/threonine-protein kinase (AKT1)
	Target type	Successful Target
	Disease	Triple negative breast cancer; Colorectal cancer;
	Drugs	Capivasertib	Drug Info

T63966 Target Info	Target Name	Vascular endothelial growth factor receptor 1 (FLT-1)
	Target type	Successful Target
	Disease	Renal cell carcinoma; Neuroendocrine cancer;
	Drugs	Tivozanib	Drug Info

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