You are searching for: hsa04926

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T92828 Target Info	Target Name	Endothelin B receptor (EDNRB)
	Target type	Successful Target
	Disease	Cardiovascular disease; Encephalopathy;
	Drugs	Macitentan	Drug Info

T97257 Target Info	Target Name	Transforming growth factor beta 1 (TGFB1)
	Target type	Successful Target
	Disease	Idiopathic pulmonary fibrosis; Aggressive cancer;
	Drugs	Pirfenidone	Drug Info

T20761 Target Info	Target Name	Vascular endothelial growth factor A (VEGFA)
	Target type	Successful Target
	Disease	Neovascular age-related macular degeneration; Wet age-related macular degeneration;
	Drugs	Faricimab	Drug Info

T30040 Target Info	Target Name	Vascular endothelial growth factor B (VEGFB)
	Target type	Successful Target
	Disease	Metastatic colorectal cancer; Diabetic kidney disease;
	Drugs	Aflibercept	Drug Info

T99057 Target Info	Target Name	HUMAN ERK activator kinase 1 (MEK1)
	Target type	. Target
	Disease	Metastatic melanoma; Neurofibromatosis type 1;
	Drugs	Trametinib	Drug Info

T99149 Target Info	Target Name	HUMAN ERK activator kinase 2 (MEK2)
	Target type	. Target
	Disease	Metastatic melanoma; Neurofibromatosis type 1;
	Drugs	Trametinib	Drug Info

T35940 Target Info	Target Name	ERK activator kinase 1 (MEK1)
	Target type	Clinical trial Target
	Disease	Melanoma; Thyroid cancer;
	Drugs	Selumetinib	Drug Info

T34296 Target Info	Target Name	Matrix metalloproteinase-13 (MMP-13)
	Target type	Clinical trial Target
	Disease	Solid tumour/cancer; Rheumatoid arthritis;
	Drugs	Curcumin	Drug Info

T54156 Target Info	Target Name	Matrix metalloproteinase-9 (MMP-9)
	Target type	Clinical trial Target
	Disease	Stroke; Gastric adenocarcinoma;
	Drugs	GS-5745	Drug Info

T67619 Target Info	Target Name	RAC-alpha serine/threonine-protein kinase (AKT1)
	Target type	Successful Target
	Disease	Triple negative breast cancer; Colorectal cancer;
	Drugs	Capivasertib	Drug Info

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