TTD | Target: T49995

Target General Infomation
Target ID	T49995
Former ID	TTDR01211
Target Name	Arylamine N-acetyltransferase
Synonyms	Arylamine acetylase; NAT
Target Type	Research
Function	Could have a role in acetylating, and hence inactivating, the antitubercular drug isoniazid.
BioChemical Class	Acyltransferase
Target Validation	T49995
EC Number	EC 2.3.1.5
Inhibitor	(Z)-5-Benzylidene-2-thioxothiazolidin-4-one	Drug Info	[529851]
	(Z)-5-Butylidene-2-thioxothiazolidin-4-one	Drug Info	[529851]
	(Z)-5-Decylidene-2-thioxothiazolidin-4-one	Drug Info	[529851]
	(Z)-5-Hexylidene-2-thioxothiazolidin-4-one	Drug Info	[529851]
	(Z)-5-Octylidene-2-thioxothiazolidin-4-one	Drug Info	[529851]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
DRM	DRM Info
References
Ref 529851	Bioorg Med Chem. 2009 Jan 15;17(2):905-18. Epub 2008 Nov 19.Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.

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Target Information