Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | 4-Azetidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Nitrobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylthio)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-methoxyquinolin-6-yl)-4-(diethylamino)pent-2-enamide | Drug Info |
| EGFR3 --- HER2 | (S)-N-(2-hydroxyethyl)-N-methyl-2-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-5-yloxy)propanamide | Drug Info |
| EGFR3 --- HER2 | 3-[3-(Benzothiazol-2-ylsulfanylmethyl)-4,5-dihydroxy-phenyl]-2-cyano-acrylamide | Drug Info |
| EGFR3 --- HER2 | N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-[piperidin-1-yliminomethyl]-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | 4-(3'-bromoanilino)-6,7-dimethoxyquinazoline hydrochloride | Drug Info |
| EGFR3 --- HER2 | TCMDC-138467 | Drug Info |
| EGFR3 --- HER2 | (E)-3-[3-(1H-Benzoimidazol-2-ylsulfanylmethyl)-4-hydroxy-5-methoxy-phenyl]-2-cyano-acrylamide | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Chlorobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoline | Drug Info |
| EGFR3 --- HER2 | But-2-enedioic acid [4-(3-bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-amide (3-morpholin-4-yl-propyl)-amide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl piperazine-1-carboxylate | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromophenylamino)-7-ethoxy-6-methoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-(1-(3-fluorophenyl)ethyl)-1H-indazol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)-2-fluoro-N-(2-(methylsulfonyl)ethyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | TCMDC-135542 | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid piperidin-3-ylmethyl ester | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(4-benzyloxy-phenylamino)-3-cyano-7-methoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 1-(2-(4-(3-methoxy-4-(pyridin-2-ylmethoxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethyl)piperidin-4-ol | Drug Info |
| EGFR3 --- HER2 | 2-(3-(4-Chlorophenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | (R)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-((1-(methylsulfonyl)pyrrolidin-2-yl)ethynyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | TCMDC-135468 | Drug Info |
| EGFR3 --- HER2 | N-((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl)ethanesulfonamide | Drug Info |
| EGFR3 --- HER2 | N-(4-Bromophenylsulfonyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide | Drug Info |
| EGFR3 --- HER2 | 10-(3-bromophenylamino)-3,4-dihydro-2H-[1,4]dioxepino[2,3-g]quinoline-9-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-chloro-phenyl)amino]quinazolin-6-yl}urea | Drug Info |
| EGFR3 --- HER2 | GSK192082A | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(furan-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-methyl-N-(3-(4-methylpiperazin-1-yl)propyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide | Drug Info |
| EGFR3 --- HER2 | 4-(3'-iodoanilino)-6,7-diethoxyquinazoline hydrochloride | Drug Info |
| EGFR3 --- HER2 | (E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-p-tolylsulfanylmethyl-phenyl)-acrylamide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(1H-pyrrol-2-yl)thieno[2,3-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 4-(4-isopropylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | Erlotinib hydrochloride | Drug Info |
| EGFR3 --- HER2 | 2-{[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-ylamino]-methyl}-acrylic acid | Drug Info |
| EGFR3 --- HER2 | 4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-2-((dimethylamino)methyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid trans-2-piperidin-4-ylethyl ester | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl methylcarbamate | Drug Info |
| EGFR3 --- HER2 | GW784684X | Drug Info |
| EGFR3 --- HER2 | (7-Allyloxy-6-methoxyquinazolin-4-yl)-(3'-bromophenyl)amine hydrochloride | Drug Info |
| EGFR3 --- HER2 | 4-[(4'-fluorobenzyl)amino]-6,7-diethoxyquinazoline hydrochloride | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-fluorophenylamino)quinazolin-6-yloxy)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(biphenyl-4-yl)acrylate | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyanoquinolin-6-yl)-2-(morpholinomethyl)acrylamide | Drug Info |
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