| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T40016 | ||||
| Target Name | Glucocorticoid receptor | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | GW685698X | Drug Info | IC50 = 69000 nM | [552644] | |
| ZK-230211 | Drug Info | IC50 = 16 nM | [525950] | ||
| References | |||||
| Ref 552644 | Structure-activity relationships of selective GABA uptake inhibitors. Curr Top Med Chem. 2006;6(17):1861-82. | ||||
| Ref 525950 | J Med Chem. 2000 Dec 28;43(26):5010-6.Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist. | ||||
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