Search Whole Database Search Co-Targets: Examples: 5-HT 1A receptor; Acyltransferase; Schizophrenia ... Search Co-Targets by Target Name: Please select a target 5-HT 1A receptor (HTR1A) 5-HT 1B receptor (HTR1B) 5-HT 1D receptor (HTR1D) 5-HT 1E receptor (HTR1E) 5-HT 1F receptor (HTR1F) 5-HT 2B receptor (HTR2B) 5-HT 2C receptor (HTR2C) 5-HT 3A receptor (HTR3A) 5-HT 4 receptor (HTR4) 5-HT 5A receptor (HTR5A) 5-HT 6 receptor (HTR6) 5-HT 7 receptor (HTR7) Acetyl-CoA carboxylase 2 (ACACB) Acetylcholinesterase (AChE) Acid-sensing ion channel 1 (ASIC1) Adenine nucleotide translocator 1 (SLC25A4) Adenosine A1 receptor (ADORA1) Adenosine A2a receptor (ADORA2A) Adenosine A2b receptor (ADORA2B) Adenosine A3 receptor (ADORA3) Adenylate cyclase type 1 (ADCY1) Adrenergic receptor alpha-1A (ADRA1A) Adrenergic receptor alpha-1B (ADRA1B) Adrenergic receptor alpha-1D (ADRA1D) Adrenergic receptor alpha-2A (ADRA2A) Adrenergic receptor alpha-2B (ADRA2B) Adrenergic receptor alpha-2C (ADRA2C) Adrenergic receptor beta-2 (ADRB2) Adrenergic receptor beta-3 (ADRB3) Albendazole monooxygenase (CYP3A4) Aldehyde oxidase (AOX1) Aldose reductase (AKR1B1) Aldosterone synthase (CYP11B2) Alpha-galactosidase A (GLA) Alpha-glucosidase (GLA) Amyloid beta A4 protein (APP) Androgen receptor (AR) Angiopoietin 1 receptor (TEK) Angiotensin II receptor type-1 (AGTR1) Angiotensin II receptor type-2 (AGTR2) Angiotensin-converting enzyme (ACE) Angiotensinogenase renin (REN) Apoptosis regulator Bcl-2 (BCL-2) Apoptosis regulator Bcl-W (BCL-W) Apoptosis regulator Bcl-xL (BCL-xL) Arachidonate 5-lipoxygenase (5-LOX) Aromatase (CYP19A1) Aromatic-L-amino-acid decarboxylase (DDC) Aryl hydrocarbon receptor (AHR) ATM serine/threonine kinase (ATM) ATP-binding cassette transporter A1 (ABCA1) ATP-binding cassette transporter C8 (ABCC8) ATP-binding cassette transporter C9 (ABCC9) ATP-binding cassette transporter G2 (ABCG2) B2 bradykinin receptor (BDKRB2) Bacterial DD-carboxypeptidase (Bact vanYB) Bacterial Deoxyribonucleic acid (Bact DNA) Bacterial Dihydrofolate reductase (Bact DHFR) Bacterial Dihydropteroate synthetase (Bact folP) Bacterial DNA gyrase (Bact gyrase) Bacterial Fatty acid synthetase I (Bact inhA) Bacterial Fumarate reductase flavoprotein (Bact frdA) Bacterial Isoleucyl-tRNA synthetase (Bact ileS) Bacterial RNA polymerase sigma factor SigA (Bact sigA) Beta-catenin (CTNNB1) Beta-secretase 1 (BACE1) Bromodomain testis-specific protein (BRDT) Bromodomain-containing protein 2 (BRD2) Bromodomain-containing protein 3 (BRD3) Bromodomain-containing protein 4 (BRD4) C-C chemokine receptor type 2 (CCR2) C-C chemokine receptor type 4 (CCR4) C-C chemokine receptor type 5 (CCR5) C-X-C chemokine receptor type 1 (CXCR1) C-X-C chemokine receptor type 2 (CXCR2) C-X-C chemokine receptor type 4 (CXCR4) C1 esterase inhibitor (SERPING1) C5a anaphylatoxin chemotactic receptor (C5AR1) Calcineurin (PPP3CA) Calcitonin gene-related peptide receptor (CGRPR) Calcium signal-modulating cyclophilin ligand (CAML) Calcium-activated potassium channel KCa3.1 (KCNN4) Calcium-activated potassium channel KCa4.1 (KCNT1) Calcium-activated potassium channel KCa4.2 (KCNT2) Calcium-dependent chloride channel anoctamin (ANO) Calgranulin D (S100A12) Calmodulin (CALM) Candida Cytochrome P450 51 (Candi ERG11) Candida Squalene epoxidase (Candi ERG1) Candida Thymidylate synthase (Candi TMP1) Cannabinoid receptor 1 (CB1) Cannabinoid receptor 2 (CB2) Carbonic anhydrase IV (CA-IV) Carbonic anhydrase IX (CA-IX) Carbonic anhydrase VI (CA-VI) Carbonic anhydrase XII (CA-XII) Carbonic anhydrase XIV (CA-XIV) Carboxypeptidase B2 (CPB2) Carnitine O-palmitoyltransferase I (CPT1B) Casein kinase II alpha (CSNK2A1) Caspase-1 (CASP1) Caspase-7 (CASP7) Caspase-9 (CASP9) Catechol-O-methyl-transferase (COMT) Cathepsin G (CTSG) Cathepsin K (CTSK) Cationic trypsinogen (PRSS1) CDC7-related kinase (CDC7) Cellular inhibitor of apoptosis 1 (BIRC2) Cellular inhibitor of apoptosis 2 (BIRC3) Cellular tumor antigen p53 (TP53) Ceramide glucosyltransferase (UGCG) Checkpoint kinase-1 (CHK1) Cholesterol desmolase (CYP11A1) Cholinesterase (BCHE) Chymase (CYM) Ciliary neurotrophic factor receptor alpha (CNTFR) Coagulation factor IIa (F2) Coagulation factor Xa (F10) Core proteasome 20S complex (PS 20S) Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) Corticotropin-releasing factor receptor 1 (CRHR1) Corticotropin-releasing factor receptor 2 (CRHR2) CREB-binding protein (CREBBP) Cyclin-dependent kinase 1 (CDK1) Cyclin-dependent kinase 7 (CDK7) Cytochrome P450 1B1 (CYP1B1) Cytochrome P450 26 (CYP26A1) Cytochrome P450 2A6 (CYP2A6) Cytoplasmic thioredoxin reductase (TXNRD1) Diacylglycerol acyltransferase 1 (DGAT1) Diacylglycerol O-acyltransferase 2 (DGAT2) Dihydrodiol dehydrogenase type I (AKR1C3) Dihydropyrimidinase related protein 2 (DPYSL2) Dipeptidyl peptidase 4 (DPP-4) Dipeptidyl peptidase 8 (DPP-8) Dipeptidyl peptidase 9 (DPP-9) DNA topoisomerase II (TOP2) DNA [cytosine-5]-methyltransferase 1 (DNMT1) DNA [cytosine-5]-methyltransferase 3B (DNMT3B) Dopamine D1 receptor (D1R) Dopamine D3 receptor (D3R) Dopamine D5 receptor (D5R) Dopamine transporter (DAT) Dual specificity protein kinase TTK (MPS1) Dual specificity protein phosphatase 1 (DUSP1) Duffy antigen chemokine receptor (ACKR1) E2 ubiquitin-conjugating enzyme T (UBE2T) Endothelin A receptor (EDNRA) Endothelin B receptor (EDNRB) Enhancer of zeste homolog 2 (EZH2) Ephrin type-B receptor 2 (EPHB2) Ephrin type-B receptor 4 (EPHB4) Erbb4 tyrosine kinase receptor (Erbb-4) ERK activator kinase 2 (MEK2) Estrogen receptor beta (ESR2) Estrogen-related receptor-alpha (ESRRA) Eukaryotic elongation factor 2 kinase (eEF-2K) Extracellular calcium-sensing receptor (CASR) Extracellular signal-regulated kinase 1 (ERK1) Extracellular signal-regulated kinase 2 (ERK2) Farnesoid X-activated receptor (FXR) Farnesyl protein transferase (Ftase) Fatty acid synthase (FASN) Fatty acid-binding protein 1 (FABP1) Fatty aldehyde dehydrogenase (ALDH3A2) Focal adhesion kinase 1 (FAK) Folate receptor alpha (FOLR1) Follicle-stimulating hormone receptor (FSHR) Fungal Cell membrane (Fung CM) Fusion protein FGFR3-TACC3 (FGFR3-TACC3) G1/S-specific cyclin-D1 (CCND1) GABA transporter GAT-1 (SLC6A1) GABA transporter-3 (SLC6A11) GABA(A) receptor alpha-1 (GABRA1) GABA(A) receptor alpha-2 (GABRA2) GABA(A) receptor alpha-3 (GABRA3) GABA(A) receptor alpha-5 (GABRA5) GABA(A) receptor beta-2 (GABRB2) GABA(A) receptor delta (GABRD) GABA(A) receptor gamma-2 (GABRG2) GABA(A) receptor gamma-3 (GABRG3) Galanin receptor (GAL-R) Gamma-aminobutyric acid B receptor (GABBR) Gastric H(+)/K(+) ATPase alpha (ATP4A) Gastrin/cholecystokinin type B receptor (CCKBR) Geranyltranstransferase (FDPS) Glucagon receptor (GCGR) Glucocorticoid receptor (NR3C1) Glucose-dependent insulinotropic receptor (GPR119) Glutamate receptor AMPA 1 (GRIA1) Glutamate receptor AMPA 2 (GRIA2) Glutamate receptor AMPA 3 (GRIA3) Glutamate receptor AMPA 4 (GRIA4) Glutamate receptor ionotropic kainate 1 (GRIK1) Glutamate receptor ionotropic NMDA 1 (NMDAR1) Glutamate receptor ionotropic NMDA 2A (NMDAR2A) Glutamate receptor ionotropic NMDA 2B (NMDAR2B) Glutaminase (GLS) Glycine transporter GlyT-1 (SLC6A9) Glycogen synthase kinase-3 alpha (GSK-3A) Glycogen synthase kinase-3 beta (GSK-3B) Glycoprotein IIb/IIIa receptor (GPIIb/IIIa) Granulocyte colony-stimulating factor receptor (G-CSF-R) Growth hormone receptor (GHR) Growth hormone secretagogue receptor 1 (GHSR) GTPase NRas (NRAS) Guanine nucleotide exchange factor (GNEF) Haemophilus influenzae Acetylglucosamine deacetylase (Hae-influ lpxC) Heat shock protein 90 alpha (HSP90A) Heat shock protein 90 beta (HSP90B) Heparanase (HPSE) Hepatitis B virus Polymerase (HBV P) Hepatitis B virus Reverse transcriptase (HBV RT) Hepatitis C virus Non-structural 4B (HCV NS4B) Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) Hepatitis C virus Serine protease NS3/4A (HCV NS3/4A) Herpes simplex virus DNA polymerase UL30 (HSV UL30) Herpes simplex virus Helicase-primase (HSV UL8) HIF-prolyl hydroxylase 1 (HPH-1) Histamine H2 receptor (H2R) Histamine H3 receptor (H3R) Histamine H4 receptor (H4R) Histamine N-methyltransferase (HNMT) Histidine decarboxylase (HDC) Histone deacetylase 2 (HDAC2) Histone deacetylase 3 (HDAC3) Histone deacetylase 4 (HDAC4) Histone deacetylase 6 (HDAC6) HMG-CoA reductase (HMGCR) Hormone sensitive lipase (LIPE) Hormone unspecific (HOM) Human Deoxyribonucleic acid (hDNA) Human immunodeficiency virus GAG protein (HIV gag) Human immunodeficiency virus Integrase (HIV IN) Human immunodeficiency virus Protease (HIV PR) Human immunodeficiency virus Reverse transcriptase (HIV RT) Hypoxia-inducible factor 1 alpha (HIF-1A) Indoleamine 2,3-dioxygenase 1 (IDO1) Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) Influenza M2 protein (Influ M) Influenza Neuraminidase (Influ NA) Inhibitor of apoptosis protein (hIAP) Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1) Insulin receptor (INSR) Insulin-like growth factor I receptor (IGF1R) Integrin alpha-4 (ITGA4) Integrin alpha-L (ITGAL) Integrin alpha-V/beta-3 (ITGAV/B3) Interleukin 4 receptor alpha (IL4R) Interleukin-1 beta (IL1B) Interleukin-12 beta (IL12B) Interleukin-18 (IL18) Interleukin-4 (IL4) Interleukin-6 (IL6) Interleukin-8 (IL8) Intestinal maltase-glucoamylase (MGAM) Inward rectifier potassium channel Kir3.4 (KCNJ5) Isocitrate dehydrogenase (IDH) Janus kinase 1 (JAK-1) Janus kinase 3 (JAK-3) Jun N terminal kinase (JNK) Lactotransferrin (LTF) Leukocyte surface antigen Leu-16 (CD20) Leukotriene A-4 hydrolase (LTA4H) Leukotriene B4 receptor 2 (LTB4R2) Leukotriene CysLT1 receptor (CYSLTR1) Leutinizing-hormone-releasing hormone (GNRH1) Liver carboxylesterase (CES1) Luteinizing hormone receptor (LHCGR) Lysosomal alpha-glucosidase (GAA) M-phase inducer phosphatase 2 (MPIP2) Macrophage-stimulating protein receptor (RON) Mammalian target of rapamycin complex 1 (mTORC1) MAP kinase p38 (MAPK12) MAP kinase signal-integrating kinase 2 (MKNK2) MAPK signal-integrating kinase 1 (MKNK1) MAPK/ERK kinase kinase 1 (MAP3K1) MAPK/ERK kinase kinase 2 (MAP3K2) Matrix metalloproteinase-1 (MMP-1) Matrix metalloproteinase-13 (MMP-13) Matrix metalloproteinase-14 (MMP-14) Matrix metalloproteinase-7 (MMP-7) Matrix metalloproteinase-8 (MMP-8) Matrix metalloproteinase-9 (MMP-9) Melanin-concentrating hormone receptor 1 (MCHR1) Melanocortin receptor 4 (MC4R) Melatonin receptor type 1A (MTNR1A) Melatonin receptor type 1B (MTNR1B) Membrane copper amine oxidase (AOC3) Metabotropic glutamate receptor 2 (mGluR2) Metabotropic glutamate receptor 3 (mGluR3) Metabotropic glutamate receptor 5 (mGluR5) Metastasis-suppressor KiSS-1 (KISS1) Microtubule-associated protein (MAP) Mineralocorticoid receptor (MR) Mitochondrial uncoupling protein 1 (UCP1) Mitochondrial uncoupling protein 2 (UCP2) Mitochondrial uncoupling protein 3 (UCP3) Mixed lineage kinase 1 (MAP3K9) Monoamine oxidase type A (MAO-A) Monoamine oxidase type B (MAO-B) Monoglyceride lipase (MAGL) Motilin receptor (MLNR) Mucosal addressin cell adhesion molecule 1 (MADCAM1) Multidrug resistance-associated protein 1 (ABCC1) Muscarinic acetylcholine receptor M1 (CHRM1) Muscarinic acetylcholine receptor M2 (CHRM2) Muscarinic acetylcholine receptor M3 (CHRM3) Muscarinic acetylcholine receptor M4 (CHRM4) Muscarinic acetylcholine receptor M5 (CHRM5) Mycobacterium Membrane protein mmpL3 (MycB mmpL3) Mycobacterium Proton pump (MycB Prop) Mycobacterium RNA polymerase (MycB RNAP) Myophosphorylase (PYGM) NAD-dependent deacetylase sirtuin-1 (SIRT1) NEDD8-activating enzyme (NAE) Neuromedin-K receptor (TACR3) Neuronal acetylcholine receptor alpha-1 (CHRNA1) Neuronal acetylcholine receptor alpha-2 (CHRNA2) Neuronal acetylcholine receptor alpha-4 (CHRNA4) Neuronal acetylcholine receptor alpha-4/beta-2 (CHRNA4/B2) Neuronal acetylcholine receptor alpha-7 (CHRNA7) Neuronal acetylcholine receptor beta-2 (CHRNB2) Neuronal acetylcholine receptor beta-4 (CHRNB4) Neurotensin receptor type 1 (NTSR1) Neutral endopeptidase (MME) Neutrophil elastase (NE) Nicotinamide phosphoribosyltransferase (NAMPT) Nicotinic acid receptor (HCAR2) Nitric-oxide synthase endothelial (NOS3) Nitric-oxide synthase inducible (NOS2) Nociceptin receptor (OPRL1) Nuclear factor NF-kappa-B (NFKB) Opioid receptor delta (OPRD1) Opioid receptor kappa (OPRK1) Opioid receptor sigma 1 (OPRS1) Orexin receptor type 1 (HCRTR1) Orexin receptor type 2 (HCRTR2) Organic anion transporter M1 (SLCO4C1) Oxo-5-alpha-steroid 4-dehydrogenase (SRD5A) Oxytocin receptor (OTR) P2Y purinoceptor 12 (P2RY12) P2Y purinoceptor 2 (P2RY2) PAK-4 protein kinase (PAK4) Pancreatic elastase 1 (CELA1) Pancreatic triacylglycerol lipase (PNLIP) Parathyroid hormone receptor (PTH2R) Peroxisome proliferator-activated receptor alpha (PPARA) Peroxisome proliferator-activated receptor delta (PPARD) Peroxisome proliferator-activated receptor gamma (PPAR-gamma) Phosphatidylinositol-4-kinase alpha (PI4KA) Phosphodiesterase 3A (PDE3A) Phosphodiesterase 4A (PDE4A) Phosphodiesterase 4B (PDE4B) Phosphodiesterase 4D (PDE4D) Phospholipase A2 (PLA2G1B) PI3-kinase alpha (PIK3CA) PI3-kinase beta (PIK3CB) Picornavirus Capsid protein VP1 (PicVir VP1) Plasminogen (PLG) Plasmodium Beta-hydroxyacyl-ACP dehydratase (Malaria FabZ) Plasmodium Deoxyribonucleic acid (Malaria DNA) Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) Plasmodium Enoyl-ACP reductase (Malaria fabI) Plasmodium Glutamate dehydrogenase (Malaria gdh) Plasmodium Oxoacyl-[acyl-carrier protein] reductase (Malaria fabG) Platelet-activating factor receptor (PTAFR) Platelet-derived growth factor receptor alpha (PDGFRA) Pneumocystis carinii Dihydropteroate synthase (PC DHPS) Polo-like kinase 1 (PLK1) Polypeptide deformylase (PDF) Progesterone (PG) Progesterone receptor (PGR) Prolyl endopeptidase FAP (FAP) Prostacyclin receptor (PTGIR) Prostaglandin D2 receptor (PTGDR) Prostaglandin D2 receptor 2 (PTGDR2) Prostaglandin E2 receptor EP1 (PTGER1) Prostaglandin E2 receptor EP2 (PTGER2) Prostaglandin E2 receptor EP3 (PTGER3) Prostaglandin E2 receptor EP4 (PTGER4) Prostaglandin F2-alpha receptor (PTGFR) Prostaglandin G/H synthase (COX) Prostaglandin G/H synthase 1 (COX-1) Protein arginine methyltransferase 5 (PRMT5) Protein cereblon (CRBN) Protein kinase C alpha (PRKCA) Protein kinase C beta (PRKCB) Protein kinase C epsilon (PRKCE) Protein kinase C gamma (PRKCG) Protein-tyrosine phosphatase sigma (R-PTP-sigma) Proton-coupled folate transporter (SLC46A1) Puromycin-sensitive aminopeptidase (NPEPPS) Quinone reductase 2 (NQO2) Ras-related protein Rab-9A (RAB9A) Respiratory syncytial virus protein F (RSV F) Retinoic acid receptor alpha (RARA) Retinoic acid receptor beta (RARB) Retinoic acid receptor gamma (RARG) Retinoic acid receptor RXR-alpha (RXRA) Retinoic acid receptor RXR-beta (RXRB) Retinoic acid receptor RXR-gamma (RXRG) Rho-associated protein kinase 1 (ROCK1) Rho-associated protein kinase 2 (ROCK2) Ribonucleoside-diphosphate reductase M2 (RRM2) Ribosomal protein S6 kinase beta-1 (S6K1) Rotamase Pin1 (PIN1) S-nitrosoglutathione reductase (CBR1) Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) Serine/threonine PP1-alpha (PPP1CA) Serine/threonine-protein kinase ATR (FRP1) Serine/threonine-protein kinase B-raf (BRAF) Serine/threonine-protein kinase pim-2 (PIM2) Serine/threonine-protein kinase Raf (RAF) Serine/threonine-protein kinase Sgk1 (SGK1) Serum albumin (ALB) Smoothened homolog (SMO) Sodium pump subunit alpha-1 (ATP1A1) Sodium/bile acid cotransporter (SLC10A1) Sodium/glucose cotransporter 1 (SGLT1) Sodium/glucose cotransporter 2 (SGLT2) Sodium/potassium-transporting ATPase (SPT ATPase) Soluble epoxide hydrolase (EPHX2) Solute carrier family 12 member 1 (SLC12A1) Solute carrier family 12 member 3 (SLC12A3) Solute carrier family 19 member 1 (SLC19A1) Solute carrier family 22 member 8 (SLC22A8) Solute carrier family 29 member 1 (SLC29A1) Somatostatin receptor type 1 (SSTR1) Somatostatin receptor type 2 (SSTR2) Somatostatin receptor type 3 (SSTR3) Somatostatin receptor type 4 (SSTR4) Somatostatin receptor type 5 (SSTR5) Sphingosine-1-phosphate receptor 1 (S1PR1) Squalene monooxygenase (SQLE) Staphylococcus 30S ribosomal subunit (Stap-coc pbp2) Staphylococcus Leucyl-tRNA synthetase (Stap-coc leuS) Staphylococcus Plastid RNA polymerase beta (Stap-coc rpoB) Staphylococcus Topoisomerase IV (Stap-coc parC) Steroid 11-beta-hydroxylase (CYP11B1) Steroid 17-alpha-monooxygenase (S17AH) Steroid 5-alpha-reductase 2 (SRD5A2) Steroid hormone receptor ERR (ESRR) Steryl-sulfatase (STS) Stress-activated protein kinase 2a (p38 alpha) Stress-activated protein kinase 2b (p38 beta) Stress-activated protein kinase JNK1 (JNK1) Substance-K receptor (TACR2) Substance-P receptor (TACR1) Synaptic vesicle amine transporter (SLC18A2) Target of rapamycin complex 2 MAPKAP1 (MTORC2) Telomerase reverse transcriptase (TERT) TGF-beta receptor type I (TGFBR1) Thioredoxin (TXN) Thrombopoietin receptor (MPL) Thromboxane A2 receptor (TBXA2R) Thromboxane-A synthase (TBXAS1) Thymidine kinase 1 (TK1) Thymidine phosphorylase (TYMP) Thyroid hormone receptor alpha (THRA) Thyroid hormone receptor beta (THRB) TNF alpha converting enzyme (ADAM17) Toll-like receptor 7 (TLR7) Toll-like receptor 8 (TLR8) Toxic reactive metabolite (TRM) Trace amine-associated receptor-1 (TAAR1) Transforming growth factor beta 1 (TGFB1) Transient receptor potential cation channel V4 (TRPV4) Troponin C (TN-C) Tryptase alpha/beta-1 (Tryptase) Tubulin beta-2 chain (TUBB2) Tumor necrosis factor (TNF) TYK2 tyrosine kinase (TYK2) Tyrosinase (TYR) Tyrosine-protein kinase Lyn (JTK8) Tyrosine-protein kinase Mer (MERTK) Tyrosine-protein kinase UFO (AXL) Ubiquitin-like protein Nedd8 (NEDD8) Urokinase plasminogen activator surface receptor (PLAUR) Urokinase-type plasminogen activator (PLAU) Valosin-containing protein p97 (VCP) Vascular endothelial growth factor A (VEGFA) Vasopressin V1a receptor (V1AR) Vasopressin V1b receptor (V1BR) Vasopressin V2 receptor (V2R) Virus Deoxyribonucleic acid (Viru DNA) Vitamin D3 receptor (VDR) Vitamin K epoxide reductase complex 1 (VKORC1) Voltage-gated calcium channel alpha Cav1.2 (CACNA1C) Voltage-gated calcium channel alpha Cav1.3 (CACNA1D) Voltage-gated calcium channel alpha Cav2.1 (CACNA1A) Voltage-gated calcium channel alpha Cav3.1 (CACNA1G) Voltage-gated calcium channel alpha Cav3.2 (CACNA1H) Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) Voltage-gated potassium channel Kv1.5 (KCNA5) Voltage-gated potassium channel Kv11.1 (KCNH2) Voltage-gated potassium channel Kv7.1 (KCNQ1) Voltage-gated sodium channel alpha Nav1.3 (SCN3A) Voltage-gated sodium channel alpha Nav1.5 (SCN5A) Voltage-gated sodium channel alpha Nav1.7 (SCN9A) Voltage-gated sodium channel alpha Nav1.8 (SCN10A) Voltage-gated sodium channel alpha Nav1.9 (SCN11A) Wee1-like protein kinase (WEE1) X-linked inhibitor of apoptosis protein (XIAP) Xanthine dehydrogenase/oxidase (XDH) Search Co-Targets by Target Family: Please select a target family ABC transporter Acid anhydride hydrolase Acid anhydrides hydrolase Acyltransferase Aldehyde/oxo donor oxidoreductase Alkyl aryl transferase Alpha-carbonic anhydrase Amiloride-sensitive sodium channel Amyloid beta-protein peptide ATP-hydrolyzing DNA topoisomerase B-cell lymphoma Bcl-2 Beta-catenin Bile acid:sodium symporter (BASS) (TC 2.A.28) family Bromodomain Caliciviridae capsid protein Calmodulin-dependent secretion Carbon-carbon ligase Carbon-carbon lyase Carbon-nitrogen hydrolase Carbon-oxygen ligase Carboxylic ester hydrolase Cation transporting ATPase Cation-chloride cotransporter CD20 calcium channel CH-CH donor oxidoreductase CH-NH donor oxidoreductase CH-NH(2) donor oxidoreductase CH-OH donor oxidoreductase CH/CH(2) oxidoreductase Cis-trans-isomerase Cytokine receptor Cytokine: interleukin Cytokine: tumor necrosis factor Diphenol donor oxidoreductase DNA polymerase type-B DNA-directed DNA polymerase Ether bond hydrolase Folate receptor Glutamate-gated ion channel Glycosylase Glycosyltransferases Gonadotropin-releasing hormone GPCR duffy GPCR frizzled GPCR glutamate GPCR rhodopsin GPCR secretin Growth factor Heat shock protein Hepacivirus polyprotein Hexosyltransferase Influenza viruses matrix protein Integrase Integrin Intramolecular oxidoreductase Inward rectifier potassium channel Kinase Ligand-gated ion channel Major facilitator superfamily Methyltransferase Mitochondrial carrier Neurotransmitter receptor Neurotransmitter:sodium symporter Nuclear hormone receptor Oxygenase Paired donor oxygen oxidoreductase Pentosyltransferase Peptidase Phosphoric diester hydrolase Phosphoric monoester hydrolase Phosphorus-oxygen lyase PI3/PI4-kinase family. Type III PI4K subfamily Protein kinase superfamily. CAMK Ser/Thr protein kinase family S100 calcium-binding protein Serpin protein Short-chain dehydrogenases reductase Small GTPase Small GTPase superfamily Solute:sodium symporter Sulfur donor oxidoreductase Sulfuric ester hydrolase Toll-like receptor Topoisomerase GyrA ParC Transferrin Transient receptor potential catioin channel Type-B carboxylesterase/lipase Ubiquitin family Ubiquitin-conjugating enzyme family Voltage-gated ion channel Search Co-Targets by ICD-11 Defined Disease Class: Please select a disease class 1A00-1A09: Anaerobic bacterial infection 1A00-1C4Z: Bacterial infection 1A00-CA43: Postoperative inflammation 1A03: Escherichia coli intestinal infection 1A04: Clostridium difficile enterocolitis 1A24-1D9Z: Virus infection 1A2Z: Viral intestinal infection 1A36: Amoebiasis 1A40: Infectious gastroenteritis/colitis 1A61-1A6Z: Syphilis 1A70-1A7Z: Gonococcal infection 1A95: Anogenital warts 1A9Y-1A9Z: Sexually transmitted infection 1B10-1B12: Tuberculosis 1B10-1B14: HIV-infected patients with tuberculosis 1B10-1B21: Mycobacterium infection 1B10-1F85: Pulmonary disease 1B40: Rheumatic fever 1B5Y: Staphylococcal/streptococcal disease 1B72: Impetigo 1B74-1F40: Gram-positive bacterial infection 1B92: Glanders 1C1G: Lyme borreliosis 1C60-1C62: Human immunodeficiency virus disease 1C80: Viral encephalitis 1D01: Infectious meningitis 1D2Z: Dengue fever 1D51-1F53: Trypanosomiasis 1D82: Cytomegaloviral disease 1D92: Coronavirus infection 1E30-1E32: Influenza 1E50-1E51: Hepatitis virus infection 1E76: Molluscum contagiosum 1E80: Common warts 1E91: Zoster 1F00: Herpes simplex infection 1F20: Aspergillosis 1F22: Blastomycosis 1F23: Candidosis 1F25: Coccidioidomycosis 1F28-1G0Z: Skin and skin-structure infection 1F28: Dermatophytosis 1F29-1F2F: Fungal infection 1F2D: Non-dermatophyte superficial dermatomycose 1F40-1F45: Malaria 1F51: African trypanosomiasis 1F54: Leishmaniasis 1F57: Toxoplasmosis 1F61-1G2Z: Kinetoplastids 1F66: Filariasis 1F6G: Trichuriasis 1F6Y: Nematode disease 1F8Y: Trematode disease 1F90: Parasitic worm infestation 1G00: Pediculosis 1G40-1G41: Sepsis 2A00-2F9Z: Solid tumour/cancer 2A00: Brain cancer 2A20: Myeloproliferative neoplasm 2A21: Mastocytosis 2A37: Myelodysplastic syndrome 2A40: Chronic myelomonocytic leukaemia 2A41: BCR-ABL1-negative chronic myeloid leukaemia 2A60-2B33: Leukaemia 2A60-2C35: Sarcoma 2A60: Acute myeloid leukaemia 2A80-2A86: Lymphoma 2A80: Follicular lymphoma 2A81: Diffuse large B-cell lymphoma 2A82: Mature B-cell leukaemia 2A83: Multiple myeloma 2A85: Mature B-cell lymphoma 2A86: B-cell lymphoma 2A90: Mature T-cell lymphoma 2B01: Mycosis fungoides 2B02: Sezary syndrome 2B30: Hodgkin lymphoma 2B32: Immunoproliferative disorder 2B33: Malignant haematopoietic neoplasm 2B51: Osteosarcoma 2B57: Kaposi sarcoma 2B59: Liposarcoma 2B5A: Synovial sarcoma 2B5B: Gastrointestinal stromal tumour 2B5Z: Bone cancer 2B60-2D01: Squamous cell carcinoma 2B6B: Nasopharyngeal cancer 2B6D: Hypopharyngeal cancer 2B6E: Lip/oral cavity/pharynx neoplasm 2B70: Esophageal cancer 2B72: Stomach cancer 2B90: Colon cancer 2B91: Colorectal cancer 2B92: Rectum cancer 2C00: Anal cancer 2C0Z: Malignant intestine neoplasm 2C10: Pancreatic cancer 2C11: Malignant digestive organ neoplasm 2C12: Liver cancer 2C25: Lung cancer 2C26: Pleural mesothelioma 2C30-2C37: Skin cancer 2C30: Melanoma 2C32: Basal cell carcinoma 2C34: Neuroendocrine carcinoma 2C51: Peritoneal cancer 2C60-2C6Y: Breast cancer 2C60-2C6Z: Mammary tumour 2C72: Uterine ligament/parametrium/uterine adnexa neoplasm 2C73: Ovarian cancer 2C74: Fallopian tube cancer 2C76: Endometrial cancer 2C77: Cervical cancer 2C80: Testicular cancer 2C82: Prostate cancer 2C90: Renal cell carcinoma 2C92: Ureteral cancer 2C94: Bladder cancer 2D10: Thyroid cancer 2D11: Adrenal cancer 2D42: Head and neck cancer 2D50-2E09: Metastatic malignant neoplasm 2D50-2E2Z: Metastatic tumour 2D51: Metastatic meninges neoplasm 2D60: Metastatic lymph node neoplasm 2D70: Metastatic lung neoplasm 2D80: Metastatic liver/bile duct neoplasm 2E86: Uterine fibroid 2E92: Digestive organ benign neoplasm 2F37: Endocrine gland neoplasm 2F7C: Desmoid tumour 3A00-3A9Z: Anemia 3A02: Folate deficiency anaemia 3A20-3A2Z: Haemolytic anemia 3A51: Sickle-cell disorder 3A90: Acute disease anaemia 3B10: Coagulation defect 3B11: Christmas disease 3B14: Inherited coagulation factor deficiency 3B62: Qualitative platelet defect 3B63: Thrombocytosis 3B64: Thrombocytopenia 3C0Z: Blood-forming organ disease 4A00: Innate/adaptive immunodeficiency 4A01-4B41: Immune system disease 4A01: Adaptive immunity immunodeficiency 4A40-4A45: Autoimmune disease 4A40: Lupus erythematosus 4A41: Idiopathic inflammatory myopathy 4A42: Systemic sclerosis 4A43: Sjogren syndrome 4A44: Vasculitis 4A60: Monogenic autoinflammatory syndrome 4A80-4A8Z: Allergic/hypersensitivity disorder 4B00: Neutropenia 4B20: Sarcoidosis 4B24: Graft-versus-host disease 5A00: Hypo-thyroidism 5A02: Thyrotoxicosis 5A10-5A11: Type-1/2 diabete 5A10: Diabetes mellitus 5A11: Type 2 diabetes mellitus 5A2Y: Acute diabete complication 5A41: Hypo-glycaemia 5A44: Insulin-resistance syndrome 5A4Y: Pancreatic internal secretion disorder 5A50: Hypo-parathyroidism 5A51: Hyper-parathyroidism 5A60-5A61: Pituitary gland disorder 5A61: Pituitary hypofunction 5A70: Cushing syndrome 5A71: Adrenogenital disorder 5A72: Hyperaldosteronism 5A74: Adrenocortical insufficiency 5A80: Ovarian dysfunction 5A81: Testicular dysfunction 5B10: Carcinoid syndrome 5B11: Short stature 5B3Z: Endocrine disease 5B50-5B71: Nutritional deficiency 5B55-5B5F: Vitamin deficiency 5B5K: Mineral deficiency 5B80-5B81: Obesity 5B91: Mineral excesses 5C50-5C59: Inborn metabolism deficiency 5C50-5D2Z: Metabolic disorder 5C51: Inborn carbohydrate metabolism error 5C52-5C59: Synthesis disorder 5C52: Inborn lipid metabolism error 5C53: Inborn energy metabolism error 5C55: Inborn purine/pyrimidine/nucleotide metabolism error 5C56: Lysosomal disease 5C57: Peroxisomal disease 5C58: Inborn porphyrin/heme metabolism error 5C59: Neurotransmitter metabolic error 5C5A: Alpha-1-antitrypsin deficiency 5C64: Mineral absorption/transport disorder 5C72: Hypo-osmolality/hyponatraemia 5C73: Acidosis 5C77: Hypo-kalaemia 5C80-5C81: Dyslipidemia 5C80: Hyper-lipoproteinaemia 5D00: Amyloidosis 6A02: Autism spectrum disorder 6A05: Attention deficit hyperactivity disorder 6A20-6A25: Psychotic disorder 6A20: Schizophrenia 6A21: Schizoaffective disorder 6A25: Primary psychotic disorder manifestation 6A60-6E23: Mood disorder 6A60: Bipolar disorder 6A70-6A7Z: Depression 6B00-6B0Z: Anxiety disorder 6B01: Panic disorder 6B04: Social anxiety disorder 6B20: Obsessive-compulsive disorder 6B40-6B45: Stress 6B40: Post-traumatic stress disorder 6B60: Dissociative neurological symptom disorder 6B80: Anorexia nervosa 6B81: Bulimia nervosa 6B82: Binge eating disorder 6C00: Enuresis 6C40: Substance abuse 6C41: Cannabis use disorder 6C43: Opioid use disorder 6C45: Cocaine use disorder 6C4A: Nicotine use disorder 6C4G: Psychoactive substances use disorder 6C4Z: Unspecific substance use disorder 6C50-6C5Z: Addictive disorder 6C73: Intermittent explosive disorder 6D71: Mild neurocognitive disorder 6D80-6D8Z: Dementia 6D83: Frontotemporal dementia 6E20-6E8Z: Mental/behavioural/neurodevelopmental disorder 7A00-7A0Z: Insomnia 7A00-7B2Z: Sleep-wake disorder 7A00: Chronic insomnia 7A20: Narcolepsy 7A4Z: Sleep-related breathing disorder 7A60-7A65: Circadian rhythm sleep disorder 7A80: Restless legs syndrome 8A00-8A0Z: Neurobehavioral disorder 8A00-8C12: Lesion 8A00-8E7Z: Nervous system disease 8A00: Parkinsonism 8A01: Choreiform disorder 8A02: Dystonic disorder 8A03: Ataxic disorder 8A04-8D87: Central nervous system disease 8A04-8E7Z: Central and peripheral nervous disease 8A04: Tremor-related disorder 8A05: Tic disorder 8A07-8A0Z: Movement disorder 8A20-8A23: Neurodegenerative disorder 8A20: Alzheimer disease 8A40: Multiple sclerosis 8A43: Neuromyelitis optica 8A61-8A6Z: Epilepsy/seizure 8A62: Epileptic encephalopathy 8A66: Status epilepticus 8A80-8A84: Headache 8A80: Migraine 8A81: Tension-type headache 8B10-8B11: Ischemia 8B10: Transient ischaemic attack 8B11: Cerebral ischaemic stroke 8B1Z: Cerebral ischaemia 8B20: Ischaemic/haemorrhagic stroke 8B22-8B2Z: Cerebrovascular disease 8B60: Motor neuron disease 8B61: Muscular atrophy 8B82: Trigeminal nerve disorder 8B93: Radiculopathy 8C0Z: Neuropathy 8C6Y: Myasthenia gravis 8C70-8E61: Brain disease 8C70: Muscular dystrophy 8C71: Myotonic disorder 8D60: Increased intracranial pressure 8D64: Hydrocephalus 8D8A: Focal/segmental autonomic disorder 8E43: General pain disorder 8E47: Encephalopathy 9A02: Eyelid inflammatory disorder 9A60: Conjunctiva disorder 9A76-9A78: Corneal disease 9A96: Anterior uveitis 9B10: Cataract 9B70: Inherited retinal dystrophy 9B71: Retinopathy 9B72: Retinal inflammation 9B74: Retinal vascular occlusion 9B75: Macular degeneration 9B76: Degenerative high myopia 9B78: Vitreoretinopathy 9C61: Glaucoma 9C82: Extraocular muscle disorder 9C84: Nystagmus 9D45: Light sensitivity impairment 9E1Z: Visual system disease AA00-AA13: Otitis externa AA80-AB0Z: Otitis media AB31: Episodic vestibular syndrome BA00-BA04: Hypertension BA00-BE2Z: Cardiovascular disease BA00: Essential hypertension BA03: Hypertensive crisis BA04: Secondary hypertension BA20-BA21: Hypotension BA21: Orthostatic hypotension BA40-BA6Z: Ischemic heart disease BA40: Angina pectoris BA41-BA42: Heart disease BA41-BA43: Myocardial infarction BA43: Coronary thrombosis BA6Z: Ischaemic heart disease BA80: Coronary atherosclerosis BA85: Coronary vasospastic disease BA86: Coronary microvascular disease BB00: Pulmonary thromboembolism BB01: Pulmonary hypertension BB40-BA42: Endocarditis BC43: Cardiomyopathy BC45: Cardiomegaly BC63: Conduction disorder BC65: Genetic cardiac arrhythmia BC71: Ventricular tachyarrhythmia BC81: Supraventricular tachyarrhythmia BC9Z: Cardiac arrhythmia BD10-BD1Z: Heart failure BD11: Left ventricular failure BD40: Arterial occlusive disease BD4Z: Chronic arterial occlusive disease BD50: Aneurysm/dissection BD52: Arteries/arterioles disorder BD54: Diabetic foot ulcer BD71: Deep vein thrombosis BD72: Venous thromboembolism BD9Z: Lymphatic vessel/lymph nodes disorder BE2Z: Circulatory system disease CA00: Nasopharyngitis CA07-CA4Z: Respiratory infection CA07: Acute upper respiratory infection CA08: Vasomotor/allergic rhinitis CA20: Bronchitis CA21: Emphysema CA22: Chronic obstructive pulmonary disease CA23: Asthma CA24: Bronchiectasis CA25: Cystic fibrosis CA40: Pneumonia CB00: Acute respiratory distress syndrome CB02: Pulmonary eosinophilia CB03: Idiopathic interstitial pneumonitis CB40-CB7Z: Respiratory system disease DA02: Lips/oral mucosa miscellaneous disorder DA08: Dental disease DA21: Oesophagus motility disorder DA22: Gastro-oesophageal reflux disease DA24: Oesophagitis DA25: Oesophageal ulcer DA41: Gastroduodenal motor/secretory disorder DA42-DA60: Chemotherapy/radiotherapy-induced mucositis DA42-DA63: Helicobacter infection DA42: Gastritis DA43-DA4Y: Stomach disease DA60: Gastric ulcer DA61: Peptic ulcer DA63: Duodenal ulcer DA91-DB30: Postoperative ileus DA93: Small intestine motility disorder DB32: Large intestine motility disorder DB61-DD30: Arterial thrombosis DB61-GB90: Thrombosis DB90-DB9Z: Liver disease DB91: Acute/subacute hepatic failure DB92: Non-alcoholic fatty liver disease DB93: Hepatic fibrosis/cirrhosis DB94: Alcoholic liver disease DB96: Autoimmune liver disease DB98: Liver vascular disorder DC11: Cholelithiasis DC30-DC3Z: Pancreatic malfunction DC31-DC34: Pancreatitis DC35-DC3Z: Pancreas disease DD70: Crohn disease DD71: Ulcerative colitis DD72: Indeterminate colitis DD90: Oesophageal/gastroduodenal disorder DD91: Irritable bowel syndrome DD93: Infants/toddlers/children functional digestive disorder DE2Z: Digestive system disease EA00-EM0Z: Skin disease EA60: Skin fungal infection disorder EA80-EA89: Eczema EA80: Atopic eczema EA81: Seborrhoeic dermatitis EA90: Psoriasis EA91: Lichen planus EB00-EB05: Urticaria EB21: Pyoderma gangrenosum EB40: Pemphigus EB44: Dermatitis herpetiformis EB50-EB5Z: Cutaneous lupus erythematosus EC23: Skin pigmentation genetic disorder EC32: Dystrophic epidermolysis bullosa EC90: Pruritus EC91: Prurigo ED56: Keratosis pilaris ED60: Acquired hypermelanosis ED61: Acquired melanotic macule/lentigine ED63: Acquired hypomelanotic disorder ED70: Alopecia ED72: Hirsutism ED80: Acne vulgaris ED90: Rosacea ED91: Sebaceous gland disorder ED92: Hidradenitis suppurativa EE00: Hyperhidrosis EE12: Nail/perionychium infection EE40: Dermal/subcutaneous connective tissue atrophy/degeneration EF20: Acquired cutaneous blood vessel malformation EG00: Extremities vasodilatation EK00-EK0Z: Contact dermatitis EK02: Irritant contact dermatitis EK20: Fragrance/cosmetics phototoxic reaction EK71: Skin tag/polyp EK90: Epidermal dysplasias EL8Y: Skin postprocedural disorder FA00-FA05: Osteoarthritis FA01: Knee osteoarthritis FA10: Joint direct infection FA11: Reactive arthropathy FA20: Rheumatoid arthritis FA21: Psoriatic arthritis FA24: Juvenile idiopathic arthritis FA25: Gout FA2Z: Inflammatory arthropathy FA92: Inflammatory spondyloarthritis FB31: Muscle calcification/ossification FB32-FB3Z: Muscle disorder FB53: Shoulder lesion FB56: Soft tissue disorder FB83: Low bone mass disorder FB85: Bone paget disease FB86: Bone growth disorder FC0Z: Musculoskeletal system/connective tissue disease GA10: Endometriosis GA14-GC01: Fibrosis GA20-GA21: Bleeding disorder GA20: Menstrual cycle bleeding disorder GA30: Menopausal disorder GA31: Female infertility GA34: Female pelvic pain GA6Z: Female genital system disease GA90: Prostate hyperplasia GA91: Prostate disease GB04: Male infertility GB40: Nephritic syndrome GB60-GB6Z: Kidney failure GB61: Chronic kidney disease GB8Y: Cystic/dysplastic kidney disease GC00: Cystitis GC01: Bladder disorder GC08: Urinary tract infection GC2Z: Urinary system disease GC50: Functional bladder disorder HA00-HA01: Sexual dysfunction HA00: Hypoactive sexual desire dysfunction HA02: Orgasmic dysfunction HA03: Ejaculatory dysfunction JA00: Abortion JA43: Postpartum haemorrhage JB00: Preterm labour/delivery JB0C: Labour/delivery anaesthesia complication JB42: Obstetric embolism JB46: Childbirth associated breast/lactation disorder JB63: Pregnancy/childbirth/puerperium maternal infection KB08: Newborn muscle tone disorder LA11: Eye anterior segment structural developmental anomaly LA90: Vascular system developmental anomaly LB20: Gallbladder/bile ducts/liver structural developmental anomaly LC30: Hair/hair growth developmental defect LD24: Skeletal anomaly LD27: Skin/mucosal anomaly LD2A: Sex development malformative disorder LD2B: Premature ageing appearance LD2F: Multiple structural anomalies syndrome LD55: Fragile X chromosome LD90: Intellectual development disorder MD12: Cough