Search Whole Database Search Poor or Non Binders of Target: Examples: SLC47A1; Acyltransferase; Alzheimer disease ... Search Poor or Non Binders of Target by Target Name: Please select a target 5-HT 1A receptor (HTR1A) 5-HT 2A receptor (HTR2A) 5-HT 2C receptor (HTR2C) 5-HT 3A receptor (HTR3A) 5-HT 6 receptor (HTR6) 5-HT 7 receptor (HTR7) Acid-sensing ion channel 3 (ASIC3) Acidic mammalian chitinase (CHIA) Acrosin (ACR) Adenosine A1 receptor (ADORA1) Adenosine A2a receptor (ADORA2A) Adenosine A2b receptor (ADORA2B) Adenosine A3 receptor (ADORA3) Adenosine deaminase (ADA) Adenosine kinase (ADK) Adenosine monophosphate deaminase (AMPD) Adenosylhomocysteinase (AHCY) Adenylate cyclase type 5 (AC5) Adipocyte-derived leucine aminopeptidase (ERAP1) Adrenergic receptor alpha-1A (ADRA1A) Adrenergic receptor alpha-1B (ADRA1B) Adrenergic receptor alpha-1D (ADRA1D) Adrenergic receptor alpha-2A (ADRA2A) Adrenergic receptor beta-1 (ADRB1) Adrenergic receptor beta-2 (ADRB2) Adrenergic receptor beta-3 (ADRB3) Aggrecanase-1 (ADAMTS4) Alanine/serine/cysteine transporter 2 (SLC1A5) Aldehyde oxidase (AOX1) Aldose reductase (AKR1B1) ALK tyrosine kinase receptor (ALK) Alkaline phosphatase (ALPPL2) Alkaline phosphatase tissue-nonspecific (ALPL) Alpha-galactosidase A (GLA) Alpha-glucosidase (GLA) Alpha-mannosidase (MANA) Aminopeptidase N (ANPEP) Amyloid beta A4 protein (APP) Androgen receptor (AR) Angiopoietin 1 receptor (TEK) Angiotensin-converting enzyme (ACE) Angiotensinogenase renin (REN) AP endonuclease 1 (APEX1) Apoptosis regulator Bcl-2 (BCL-2) Apoptosis regulator Bcl-W (BCL-W) Apoptosis regulator Bcl-xL (BCL-xL) Apoptosis signal-regulating kinase 1 (MAP3K5) Arachidonate 12-lipoxygenase (12-LOX) Arachidonate 15-lipoxygenase (15-LOX) Arachidonate 5-lipoxygenase (5-LOX) Aromatase (CYP19A1) Aromatic-L-amino-acid decarboxylase (DDC) Aryl hydrocarbon receptor (AHR) Asialoglycoprotein receptor 1 (ASGR1) ATM serine/threonine kinase (ATM) ATP-binding cassette transporter G2 (ABCG2) ATP-citrate synthase (ACLY) ATPase family AAA domain containing 2 (ATAD2) Aurora kinase A (AURKA) Aurora kinase B (AURKB) Aurora kinase C (AURKC) B-cell lymphoma 6 protein (BCL-6) B-cell receptor CD22 (CD22) B1 bradykinin receptor (BDKRB1) Bacterial Cystathionine beta-lyase (Bact metC) Bacterial Dihydropteroate synthetase (Bact folP) Bacterial Fatty acid synthetase I (Bact inhA) Bacterial Hydroxymethyl-dihydropterin pyrophosphokinase (Bact folK) Bacterial Lethal factor (Bact lef) Bacterial NADH-dependent enoyl-ACP reductase (Bact fabI) Bacterial Phospho-MurNAc-pentapeptide translocase (Bact MraY) Bacterial Phosphoshikimate1-carboxyvinyltransferase (Bact aroA) Beta-adrenergic receptor kinase 1 (ADRBK1) Beta-catenin (CTNNB1) Beta-galactosidase (GLB1) Beta-glucuronidase (GUSB) Beta-secretase 1 (BACE1) Beta-site APP-cleaving enzyme 2 (BACE2) Bone morphogenetic protein 1 (BMP1) Branched-chain-amino-acid transaminase 1 (BCAT1) Branched-chain-amino-acid transaminase 2 (BCAT2) Bromodomain adjacent to zinc finger 2B (BAZ2B) Bromodomain and PHD finger containing 1 (BRPF1) Bromodomain testis-specific protein (BRDT) Bromodomain-containing protein 4 (BRD4) Bromodomain-containing protein 9 (BRD9) C-C chemokine receptor type 1 (CCR1) C-C chemokine receptor type 3 (CCR3) C-C chemokine receptor type 4 (CCR4) C-C chemokine receptor type 5 (CCR5) C-C chemokine receptor type 8 (CCR8) C-X-C chemokine receptor type 4 (CXCR4) C5a anaphylatoxin chemotactic receptor (C5AR1) Calcitonin gene-related peptide receptor (CGRPR) Calpain-1 (CAPN1) CaM-kinase II (CAMK2) cAMP-dependent chloride channel (CFTR) Candida Chitin synthase 1 (Candi CHS1) Candida Mannose-6-phosphate isomerase (Candi PMI1) Candida Peptide N-myristoyltransferase (Candi NMT1) Cannabinoid receptor 1 (CB1) Cannabinoid receptor 2 (CB2) Carbonic anhydrase I (CA-I) Carbonic anhydrase II (CA-II) Carbonic anhydrase IV (CA-IV) Carbonic anhydrase IX (CA-IX) Carbonic anhydrase VI (CA-VI) Carbonic anhydrase VII (CA-VII) Carbonic anhydrase XII (CA-XII) Carbonic anhydrase XIV (CA-XIV) Carboxypeptidase A1 (CPA1) Carboxypeptidase B1 (CPB1) Carboxypeptidase B2 (CPB2) Casein kinase I alpha (CSNK1A1) Casein kinase I delta (CSNK1D) Casein kinase I epsilon (CSNK1E) Casein kinase II alpha (CSNK2A1) Caspase-1 (CASP1) Caspase-3 (CASP3) Caspase-6 (CASP6) Caspase-7 (CASP7) Caspase-8 (CASP8) Cathepsin B (CTSB) Cathepsin G (CTSG) Cathepsin H (CTSH) Cathepsin K (CTSK) Cathepsin L (CTSL) Cathepsin S (CTSS) Cathepsin V (CTSV) Cationic trypsinogen (PRSS1) CDC-like kinase 1 (CLK1) CDC7-related kinase (CDC7) Cellular inhibitor of apoptosis 1 (BIRC2) Ceramide glucosyltransferase (UGCG) Checkpoint kinase-1 (CHK1) Cholesteryl ester transfer protein (CETP) Choline kinase (CHKA) Chromobox protein homolog 7 (CBX7) Chymase (CYM) Chymotrypsin-C (CLCR) Coagulation factor IX (F9) Coagulation factor VII (F7) Coagulation factor Xa (F10) Coagulation factor XI (F11) Coagulation factor XIIIA (F13A1) Complement C1s component (C1S) Complement factor D (CFD) Coronavirus Main proteinase (CoV 1a) Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) CREB-binding protein (CREBBP) Cyclic ADP-ribose hydrolase 1 (CD38) Cyclin-dependent kinase 1 (CDK1) Cyclin-dependent kinase 2 (CDK2) Cystathionine gamma-lyase (CTH) Cysteines of Keap1 (KEAP1 Cysteines) Cystine/glutamate transporter (SLC7A11) Cytidine deaminase (CDA) Cytochrome P450 1B1 (CYP1B1) Cytochrome P450 24 (CYP24A1) Cytochrome P450 2A6 (CYP2A6) Cytochrome P450 2B6 (CYP2B6) Cytomegalovirus Protease (CMV UL80) Cytosolic phospholipase A2 (GIVA cPLA2) D-amino acid oxidase (DAO) Delta-aminolevulinic acid dehydratase (ALAD) Delta-tryptase (TPSD1) Dengue virus NS2B/NS3 protease (DENV NS2B/NS3) Deoxyribonuclease I (DNASE1) Diacylglycerol O-acyltransferase 2 (DGAT2) Diamine oxidase (AOC1) Dibasic-processing enzyme (Furin) Dihydrofolate reductase (DHFR) Dihydroorotate dehydrogenase (DHODH) Dipeptidyl peptidase I (CTSC) DNA polymerase alpha catalytic p180 (POLA1) DNA topoisomerase I (TOP1) DNA topoisomerase II (TOP2) DNA topoisomerase II alpha (TOP2A) DNA [cytosine-5]-methyltransferase 1 (DNMT1) DNA [cytosine-5]-methyltransferase 3A (DNMT3A) DNA [cytosine-5]-methyltransferase 3B (DNMT3B) DNA-binding factor KBF1 (p105) DNA-dependent protein kinase catalytic (PRKDC) Dopamine beta hydroxylase (DBH) Dopamine D1 receptor (D1R) Dopamine D2 receptor (D2R) Dopamine D4 receptor (D4R) Dopamine transporter (DAT) Dual specificity phosphatase Cdc25 (CDC25) Dual specificity protein kinase TTK (MPS1) Dual-specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A) dUTP pyrophosphatase (DUT) E-selectin (SELE) Early activation antigen CD69 (CD69) Ectonucleoside triphosphate diphosphohydrolase 1 (CD39) Embryonic ectoderm development protein (EED) Endopeptidase S1P (MBTPS1) Endoplasmic reticulum aminopeptidase 2 (ERAP2) Endothelial plasminogen activator inhibitor (SERPINE1) Endothelin A receptor (EDNRA) Endothelin B receptor (EDNRB) Endothelin-converting enzyme 1 (ECE1) Enhancer of zeste homolog 2 (EZH2) Ephrin type-A receptor 2 (EPHA2) Ephrin type-B receptor 2 (EPHB2) Erbb2 tyrosine kinase receptor (HER2) ERK activator kinase 1 (MEK1) Estradiol 17 beta-dehydrogenase 1 (17-beta-HSD1) Estrogen receptor (ESR) Estrogen receptor beta (ESR2) Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) Eukaryotic initiation factor 4E (EIF4E) Excitatory amino acid transporter 1 (SLC1A3) Excitatory amino acid transporter 2 (SLC1A2) Excitatory amino acid transporter 3 (SLC1A1) Extracellular lysophospholipase D (E-NPP2) Extracellular matrix receptor III (CD44) Extracellular signal-regulated kinase 1 (ERK1) Extracellular signal-regulated kinase 2 (ERK2) Farnesoid X-activated receptor (FXR) Farnesyl protein transferase (Ftase) Fatty acid desaturase 2 (FADS2) Fatty acid synthase (FASN) Fatty acid-binding protein 4 (FABP4) Fibroblast growth factor receptor 1 (FGFR1) FK506-binding protein 1A (FKBP1A) FK506-binding protein 4 (FKBP4) FK506-binding protein 5 (FKBP5) Fms-like tyrosine kinase 3 (FLT-3) Follicle-stimulating hormone receptor (FSHR) Fructose-1,6-bisphosphatase (FBP) Fusion protein Bcr-Abl (Bcr-Abl) Fyn tyrosine protein kinase (FYN) G protein coupled receptor 81 (HCAR1) G-protein coupled bile acid receptor 1 (GPBAR1) GABA transaminase (ABAT) GABA transporter GAT-1 (SLC6A1) GABA transporter-3 (SLC6A11) GABA(A) receptor rho1 (GABRR1) Galectin-3 (LGALS3) Gamma-aminobutyric acid B receptor (GABBR) Gamma-aminobutyric acid transporter 4 (SLC6A11) Gastric alcohol dehydrogenase (ADH7) Gastric H(+)/K(+) ATPase (Proton pump) Gastrin/cholecystokinin type B receptor (CCKBR) Geranyltranstransferase (FDPS) Glucagon receptor (GCGR) Glucocorticoid receptor (NR3C1) Glucose-6-phosphate dehydrogenase (G6PD) Glucose-6-phosphate translocase (SLC37A4) Glucosylceramidase (GBA) Glutamate carboxypeptidase II (GCPII) Glutamate receptor AMPA 1 (GRIA1) Glutamate receptor AMPA 2 (GRIA2) Glutamate receptor AMPA 3 (GRIA3) Glutamate receptor AMPA 4 (GRIA4) Glutamate receptor ionotropic kainate 1 (GRIK1) Glutamate receptor ionotropic kainate 2 (GRIK2) Glutamate receptor ionotropic kainate 4 (GluK4) Glutathione reductase (GR) Glutathione S-transferase A2 (GSTA2) Glutathione S-transferase P (GSTP1) Glutathione-dependent PGD synthase (HPGDS) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Glycine receptor (GlyR) Glycine transporter GlyT-1 (SLC6A9) Glycogen phosphorylase (PYG) Glycogen phosphorylase muscle form (GP) Glycogen synthase kinase-3 alpha (GSK-3A) Glycogen synthase kinase-3 beta (GSK-3B) Glycoprotein IIb/IIIa receptor (GPIIb/IIIa) Golgi alpha-mannosidase II (MAN2A1) Group IIA phospholipase A2 (GIIA sPLA2) GTPase HRas (HRAS) Heat shock protein 90 alpha (HSP90A) Heat shock protein 90 beta (HSP90B) Hematopoietic cell kinase (HCK) HepG2 glucose transporter (SLC2A1) Herpes simplex virus DNA polymerase UL30 (HSV UL30) Herpes simplex virus Ribonucleoside-diphosphate reductase (HSV RIR1) Herpesvirus ubiquitin-specific protease (HAUSP) HIF-prolyl hydroxylase 1 (HPH-1) HIF-prolyl hydroxylase 2 (HPH-2) Histamine H1 receptor (H1R) Histamine H2 receptor (H2R) Histamine H3 receptor (H3R) Histamine H4 receptor (H4R) Histone acetyltransferase KAT2B (KAT2B) Histone acetyltransferase p300 (EP300) Histone deacetylase 1 (HDAC1) Histone deacetylase 2 (HDAC2) Histone deacetylase 3 (HDAC3) Histone deacetylase 4 (HDAC4) Histone deacetylase 5 (HDAC5) Histone deacetylase 6 (HDAC6) Histone deacetylase 7 (HDAC7) Histone deacetylase 8 (HDAC8) Histone deacetylase 9 (HDAC9) Histone lysine demethylase PHF8 (PHF8) Histone-arginine methyltransferase CARM1 (CARM1) Histone-lysine N-methyltransferase (HLNM) Histone-lysine N-methyltransferase EHMT2 (EHMT2) Histone-lysine N-methyltransferase SETD7 (SETD7) HMG-CoA reductase (HMGCR) Hormone sensitive lipase (LIPE) Human immunodeficiency virus Envelope glycoprotein gp160 (HIV env) IL-1 receptor-associated kinase 1 (IRAK1) Ileal sodium/bile acid cotransporter (SLC10A2) Indoleamine 2,3-dioxygenase 1 (IDO1) Indoleamine 2,3-dioxygenase 2 (IDO2) Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) Influenza Polymerase acidic endonuclease (Influ PA) Inhibitor of apoptosis protein (hIAP) Inhibitor of nuclear factor kappa-B kinase beta (IKKB) Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) Insulin receptor (INSR) Insulin-like growth factor I receptor (IGF1R) Integrin alpha-4/beta-1 (ITGA4/B1) Integrin alpha-4/beta-7 (ITGA4/B7) Integrin alpha-5/beta-1 (ITGA5/B1) Integrin alpha-V/beta-3 (ITGAV/B3) Integrin alpha-V/beta-5 (ITGAV/B5) Interleukin 8 receptor (IL8R) Intestinal maltase-glucoamylase (MGAM) Isoleucyl-tRNA synthetase (IARS) Janus kinase 2 (JAK-2) Janus kinase 3 (JAK-3) Kallikrein-5 (KLK5) Kallikrein-6 (KLK6) Kallikrein-7 (KLK7) Ketohexokinase (KHK) Kynurenic acid receptor (GPR35) L-lactate dehydrogenase (LDH) L-selectin (SELL) Lactase-phlorizin hydrolase (LCT) Lactate dehydrogenase A (LDHA) Lactoylglutathione lyase (GLO1) Lanosterol 14-alpha demethylase (CYP51A1) Large neutral amino acids transporter 1 (SLC7A5) LCK tyrosine protein kinase (LCK) Leukocyte common antigen (PTPRC) Leukotriene A-4 hydrolase (LTA4H) LIM domain kinase-1 (LIMK-1) Liver carboxylesterase (CES1) Liver organic anion transporter 2 (SLCO1B3) Long transient receptor potential channel 2 (TRPM2) Lysine-specific demethylase 3A (KDM3A) Lysine-specific demethylase 4A (KDM4A) Lysine-specific demethylase 4C (KDM4C) Lysine-specific demethylase 4E (KDM4E) Lysine-specific demethylase 5A (KDM5A) Lysine-specific demethylase 7A (KDM7A) Lysine-specific histone demethylase 1 (LSD) Lysine-specific histone demethylase 1B (KDM1B) Lysosomal alpha-glucosidase (GAA) Lysyl oxidase (LOX) M-phase inducer phosphatase 1 (MPIP1) M-phase inducer phosphatase 2 (MPIP2) M-phase inducer phosphatase 3 (MPIP3) Macrophage migration inhibitory factor (MIF) Malonyl-CoA decarboxylase (MLYCD) Mammalian disintegrin-metalloprotease (ADAM10) MAPK-activated protein kinase 2 (MAPKAPK2) Matrix metalloproteinase-1 (MMP-1) Matrix metalloproteinase-10 (MMP-10) Matrix metalloproteinase-12 (MMP-12) Matrix metalloproteinase-13 (MMP-13) Matrix metalloproteinase-14 (MMP-14) Matrix metalloproteinase-2 (MMP-2) Matrix metalloproteinase-3 (MMP-3) Matrix metalloproteinase-7 (MMP-7) Matrix metalloproteinase-8 (MMP-8) Matrix metalloproteinase-9 (MMP-9) Melanin-concentrating hormone receptor 1 (MCHR1) Melanocortin receptor 1 (MC1R) Melanocortin receptor 3 (MC3R) Melanocortin receptor 4 (MC4R) Melanocortin receptor 5 (MC5R) Melanoma inhibitor of apoptosis protein (ML-IAP) Melatonin receptor type 1A (MTNR1A) Melatonin receptor type 1B (MTNR1B) Membrane copper amine oxidase (AOC3) Membrane-associated lectin type-C (CD209) Metabotropic glutamate receptor 1 (mGluR1) Metabotropic glutamate receptor 2 (mGluR2) Metabotropic glutamate receptor 3 (mGluR3) Metabotropic glutamate receptor 4 (mGluR4) Metabotropic glutamate receptor 5 (mGluR5) Metabotropic glutamate receptor 6 (mGluR6) Metabotropic glutamate receptor 7 (mGluR7) Metabotropic glutamate receptor 8 (mGluR8) Methionine aminopeptidase 2 (METAP2) Methionyl aminopeptidase 1 (METAP1) Microtubule-associated protein tau (MAPT) Microtubule-associated protein tau phosphorylation (MAPT p) Monoglyceride lipase (MAGL) Mucosal addressin cell adhesion molecule 1 (MADCAM1) Multidrug and toxin extrusion protein 2 (MATE2) Multidrug resistance protein 1 (ABCB1) Multidrug resistance-associated protein 1 (ABCC1) Muscarinic acetylcholine receptor M1 (CHRM1) Muscarinic acetylcholine receptor M2 (CHRM2) Muscarinic acetylcholine receptor M3 (CHRM3) Muscarinic acetylcholine receptor M4 (CHRM4) Muscarinic acetylcholine receptor M5 (CHRM5) Mycobacterium Isocitrate lyase (MycB icl) Mycobacterium Thymidine monophosphate kinase (MycB tmk) Myelin-associated glycoprotein (MAG) Myeloperoxidase (MPO) Myophosphorylase (PYGM) Myosin light kinase (MYLK) Na(+)/Cl(-) betaine/GABA transporter (SLC6A12) NAD-dependent deacetylase sirtuin-1 (SIRT1) NAD-dependent deacetylase sirtuin-2 (SIRT2) NAD-dependent deacetylase sirtuin-3 (SIRT3) NAD-dependent deacetylase sirtuin-5 (SIRT5) NADPH oxidase 2 (CYBB) Neonatal Fc receptor (FCGRT) Neuromedin-K receptor (TACR3) Neuronal acetylcholine receptor alpha-1 (CHRNA1) Neuronal acetylcholine receptor alpha-3/beta-4 (CHRNA3/B4) Neuronal acetylcholine receptor alpha-4/beta-2 (CHRNA4/B2) Neuronal acetylcholine receptor alpha-7 (CHRNA7) Neuropeptide Y receptor type 1 (NPY1R) Neuropeptide Y receptor type 2 (NPY2R) Neurotensin receptor type 1 (NTSR1) Neutral endopeptidase (MME) Neutrophil elastase (NE) NF-kappa-B-activating kinase (TBK1) Nicotinamide phosphoribosyltransferase (NAMPT) Nicotinic acid receptor (HCAR2) NIMA-related kinase 2 (NEK2) Nitric-oxide synthase brain (NOS1) Nitric-oxide synthase endothelial (NOS3) Nitric-oxide synthase inducible (NOS2) Nociceptin receptor (OPRL1) Norepinephrine transporter (NET) Nuclear receptor ROR-gamma (RORG) O-6-methylguanine-DNA-alkyltransferase (MGMT) Opioid receptor delta (OPRD1) Opioid receptor kappa (OPRK1) Opioid receptor mu (MOP) Opioid receptor sigma 1 (OPRS1) Orexin receptor type 1 (HCRTR1) Organic anion transporter B (SLCO2B1) Organic cation transporter 3 (OCT3) Orotidine 5'-monophosphate decarboxylase (UMPS) Oxysterols receptor LXR-alpha (NR1H3) P-selectin (SELP) P-selectin glycoprotein ligand 1 (SELPLG) P2X purinoceptor 7 (P2RX7) P2Y purinoceptor 1 (P2RY1) P2Y purinoceptor 12 (P2RY12) P2Y purinoceptor 14 (P2RY14) P2Y purinoceptor 2 (P2RY2) p53-binding protein Mdm4 (MDM4) Pancreatic triacylglycerol lipase (PNLIP) Parathyroid hormone 1 receptor (PTH1R) Pepsinogen-5 (PGA5) Peptidyl arginine deiminase type IV (PADI4) Peroxisome proliferator-activated receptor alpha (PPARA) Peroxisome proliferator-activated receptor delta (PPARD) Peroxisome proliferator-activated receptor gamma (PPAR-gamma) Phenylethanolamine N-methyltransferase (PNMT) Phosphodiesterase 10A (PDE10) Phosphodiesterase 11A (PDE11A) Phosphodiesterase 2A (PDE2A) Phosphodiesterase 3A (PDE3A) Phosphodiesterase 3B (PDE3B) Phosphodiesterase 4B (PDE4B) Phosphodiesterase 5A (PDE5A) Phosphodiesterase 7A (PDE7A) Phosphodiesterase 9 (PDE9) Phosphogluconate dehydrogenase (PGD) Phosphoglycerate dehydrogenase (PHGDH) Phosphoinositide dependent protein kinase-1 (PDPK1) Phospholipase A2 (PLA2G1B) Phosphoribosylaminoimidazolecarboxamide formyltransferase (ATIC) PI3-kinase alpha (PIK3CA) PI3-kinase beta (PIK3CB) PI3-kinase delta (PIK3CD) PI3-kinase gamma (PIK3CG) Plasma kallikrein (KLKB1) Plasminogen (PLG) Plasminogen activator inhibitor (PAI) Plasmodium CDK Pfmrk (Malaria Pfmrk) Plasmodium Enoyl-ACP reductase (Malaria fabI) Plasmodium Hexose transporter 1 (Malaria ht1) Plasmodium Plasmepsin 2 (Malaria PLA2) Platelet-activating factor acetylhydrolase (PLA2G7) Platelet-derived growth factor receptor beta (PDGFRB) Polo-like kinase 1 (PLK1) Poly [ADP-ribose] glycohydrolase (PARG) Poly [ADP-ribose] polymerase 1 (PARP1) Polyamine oxidase (PAOX) Polypeptide deformylase (PDF) Positive transcription elongation factor b (P-TEFb) Pregnane X receptor (NR1I2) Presynaptic density protein 95 (DLG4) Prolyl endopeptidase (PREP) Prolylcarboxypeptidase (PRCP) Prostacyclin synthase (PTGIS) Prostaglandin E synthase (PTGES) Prostaglandin E2 receptor EP1 (PTGER1) Prostaglandin G/H synthase (COX) Prostatic acid phosphatase (ACPP) Proteasome beta-10 (PS beta-10) Proteasome beta-5 (PS beta-5) Protein arginine methyltransferase 1 (PRMT1) Protein arginine methyltransferase 3 (PRMT3) Protein arginine methyltransferase 5 (PRMT5) Protein kinase C alpha (PRKCA) Protein kinase C beta (PRKCB) Protein kinase C delta (PRKCD) Protein kinase C epsilon (PRKCE) Protein kinase C gamma (PRKCG) Protein kinase C iota (PRKCI) Protein kinase C theta (PRKCQ) Protein kinase R (PKR) Protein phosphatase 1A (PPM1A) Protein tyrosine phosphatase beta (PTPRB) Protein tyrosine phosphatase IVA 1 (PRL-1) Protein-tyrosine phosphatase SHP-1 (PTPN6) Protein-tyrosine phosphatase SHP-2 (PTPN11) Proteinase activated receptor 1 (F2R) Proteinase activated receptor 2 (PAR2) Proto-oncogene c-Met (MET) Proto-oncogene c-RAF (c-RAF) Protoporphyrinogen oxidase (PPOX) Purine nucleoside phosphorylase (PNP) Pyruvate dehydrogenase kinase 1 (PDHK1) Pyruvate dehydrogenase kinase 2 (PDHK2) Quinone reductase 1 (NQO1) Quinone reductase 2 (NQO2) RAC-alpha serine/threonine-protein kinase (AKT1) RAC-beta serine/threonine-protein kinase (AKT2) RAC-gamma serine/threonine-protein kinase (AKT3) Regulator of G-protein signaling 8 (RGS8) Renal carcinoma antigen NY-REN-56 (PFKFB3) Renal carcinoma antigen NY-REN-64 (IRAK-4) Retinoic acid receptor beta (RARB) Rho-associated protein kinase 1 (ROCK1) Rho-associated protein kinase 2 (ROCK2) Ribonucleotide reductase (RIR) Ribosomal protein S6 kinase alpha-3 (RSK3) Ribosomal protein S6 kinase alpha-5 (RSK5) Ribosomal protein S6 kinase beta-1 (S6K1) Rotamase A (PPIA) Rotamase Pin1 (PIN1) S-adenosylmethionine decarboxylase proenzyme (AMD1) Serine protease hepsin (HPN) Serine Racemase (SRR) Serine/threonine-protein kinase ATR (FRP1) Serine/threonine-protein kinase B-raf (BRAF) Serine/threonine-protein kinase mTOR (mTOR) Serine/threonine-protein kinase pim-1 (PIM1) Serine/threonine-protein kinase Sgk1 (SGK1) Serine/threonine-protein phosphatase 5 (PPP5C) Serotonin transporter (SERT) Serum albumin (ALB) Serum-and glucocorticoid-inducible kinase SGK (SGK) SET domain containing 8 (KMT5A) Signal transducer and activator of transcription 1 (STAT1) Signal transducer and activator of transcription 3 (STAT3) Sodium/glucose cotransporter 1 (SGLT1) Sodium/glucose cotransporter 2 (SGLT2) Sodium/hydrogen exchanger 1 (SLC9A1) Sodium/potassium-transporting ATPase (SPT ATPase) Soluble epoxide hydrolase (EPHX2) Solute carrier family 15 member 1 (SLC15A1) Solute carrier family 15 member 2 (SLC15A2) Solute carrier family 22 member 8 (SLC22A8) Solute carrier family 28 member 2 (SLC28A2) Solute carrier family 29 member 1 (SLC29A1) Solute carrier family 47 member 1 (SLC47A1) Somatostatin receptor type 2 (SSTR2) Sorbitoldehydrogenase (SORD) Sphingomyelin synthase (SMS) Sphingosine kinase 2 (SPHK2) Sphingosine-1-phosphate receptor 3 (S1PR3) Sphingosine-1-phosphate receptor 4 (S1PR4) Squalene monooxygenase (SQLE) Staphylococcus Beta-lactamase (Stap-coc blaZ) Steroid 17-alpha-monooxygenase (S17AH) Steroid 5-alpha-reductase 1 (SRD5A1) Steroid 5-alpha-reductase 2 (SRD5A2) Sterol O-acyltransferase (SOAT) Steryl-sulfatase (STS) Stress-activated protein kinase 2a (p38 alpha) Stress-activated protein kinase JNK1 (JNK1) Stress-activated protein kinase JNK2 (JNK2) Stromelysin (SL) Strychnine-binding glycine receptor (GLRA1) Substance-K receptor (TACR2) Substance-P receptor (TACR1) Superoxide dismutase Cu-Zn (SOD Cu-Zn) Suppressor of tumorigenicity 14 protein (ST14) Tankyrase-2 (TNKS-2) Telomerase reverse transcriptase (TERT) Telomeric repeat-binding factor 2 (TERF2) TGF-beta receptor type I (TGFBR1) Thioredoxin glutathione reductase (TGR) Thromboxane A2 receptor (TBXA2R) Thromboxane-A synthase (TBXAS1) Thymidine kinase 1 (TK1) Thymidine kinase 2 (Mt-TK2) Thymidine phosphorylase (TYMP) Thymidylate synthase (TYMS) Tissue factor (F3) Tissue kallikrein (KLK1) Tissue transglutaminase (TG2) Tissue-type plasminogen activator (PLAT) Toll-like receptor 7 (TLR7) Toll-like receptor 8 (TLR8) Trace amine-associated receptor-1 (TAAR1) Transformation-sensitive protein p120 (TRPA1) Transient receptor potential cation channel V1 (TRPV1) Transient receptor potential cation channel V6 (TRPV6) Transmembrane protease serine 6 (TMPRSS6) Tropomyosin-related kinase A (TrkA) Trypanosoma Cruzipain (Trypano CYSP) Trypanosoma Pyrophosphate-dependent phosphofructokinase (Trypano pfk) Tryptase alpha/beta-1 (Tryptase) Tryptophan 2,3-dioxygenase (TDO) Tumor necrosis factor (TNF) TYK2 tyrosine kinase (TYK2) Tyrosinase (TYR) Tyrosine-protein kinase ABL1 (ABL) Tyrosine-protein kinase BRK (PTK6) Tyrosine-protein kinase BTK (ATK) Tyrosine-protein kinase CSK (CSK) Tyrosine-protein kinase EIF2AK2 (p68) Tyrosine-protein kinase Kit (KIT) Tyrosine-protein kinase Lyn (JTK8) Tyrosine-protein kinase SYK (SYK) Tyrosine-protein kinase UFO (AXL) Tyrosine-protein kinase ZAP-70 (ZAP-70) Tyrosyl-DNA phosphodiesterase 1 (TDP1) Ubiquitin carboxyl-terminal hydrolase 2 (USP2) Ubiquitin isopeptidase Y (USP8) Ubiquitin thioesterase L3 (UCHL3) Ubiquitin-protein ligase E3 Mdm2 (MDM2) UDP-glucuronosyltransferase 2B7 (UGT2B7) Urokinase plasminogen activator surface receptor (PLAUR) Urokinase plasminogen receptor (PLAUR) Urokinase-type plasminogen activator (PLAU) Vascular endothelial growth factor receptor 1 (FLT-1) Vascular endothelial growth factor receptor 2 (KDR) Vascular endothelial growth factor receptor 3 (FLT-4) Vasopressin V1a receptor (V1AR) Vasopressin V2 receptor (V2R) Virus Replicase polyprotein 1ab (Viru rep) Vitamin D3 receptor (VDR) Vitamin K-dependent protein C (PROC) Voltage-gated calcium channel alpha Cav1.2 (CACNA1C) Voltage-gated calcium channel alpha Cav2.2 (CACNA1B) Voltage-gated calcium channel alpha Cav3.2 (CACNA1H) Voltage-gated potassium channel Kv1.3 (KCNA3) Voltage-gated potassium channel Kv1.5 (KCNA5) Voltage-gated potassium channel Kv4.3 (KCND3) Voltage-gated sodium channel alpha Nav1.2 (SCN2A) Voltage-gated sodium channel alpha Nav1.4 (SCN4A) Voltage-gated sodium channel alpha Nav1.5 (SCN5A) Voltage-gated sodium channel alpha Nav1.8 (SCN10A) WD repeat-containing protein 5 (WDR5) Wee1-like protein kinase (WEE1) X-linked inhibitor of apoptosis protein (XIAP) X-prolyl aminopeptidase 2 (XPNPEP2) Xaa-Pro dipeptidase (PEPD) Xanthine dehydrogenase/oxidase (XDH) Yes tyrosine kinase (YES) Search Poor or Non Binders of Target by Target Family: Please select a target family ABC transporter Acid anhydride hydrolase Acid anhydrides hydrolase Acyltransferase Aldehyde/oxo donor oxidoreductase Alkyl aryl transferase Alpha-carbonic anhydrase Amiloride-sensitive sodium channel Amino acid-polyamine-organocation Amyloid beta-protein peptide ATP-gated P2X receptor cation channel ATP-hydrolyzing DNA topoisomerase B-cell lymphoma Bcl-2 Bactericidal permeability increasing protein Beta-catenin Bromodomain Carbon-carbon lyase Carbon-nitrogen hydrolase Carbon-oxygen ligase Carbon-sulfur lyases Carboxylic ester hydrolase CH-CH donor oxidoreductase CH-NH donor oxidoreductase CH-NH(2) donor oxidoreductase CH-OH donor oxidoreductase CH/CH(2) oxidoreductase Cis-trans-isomerase Cis-trans-isomerases Cytochrome P450 family Cytokine receptor Cytokine: tumor necrosis factor Dicarboxylate/amino acid:cation symporter Diphenol donor oxidoreductase DNA polymerase type-B Endodeoxyribonucleases Ether bond hydrolase Ezrin/radixin/moesin-binding phosphoprotein 50 Fatty acid binding protein Glutamate-gated ion channel Glycosylase Glycosyltransferases GPCR glutamate GPCR rhodopsin GPCR secretin Heat shock protein Hexosyltransferase Immunoglobulin Integrin Intramolecular oxidoreductase Intramolecular oxidoreductases Kinase Major facilitator Major facilitator superfamily MDM2/MDM4 family Methyltransferase Monovalent cation:proton antiporter-1 NADH/NADPH oxidoreductase Neurotransmitter receptor Neurotransmitter:sodium symporter Nuclear hormone receptor Oxygenase Paired donor oxygen oxidoreductase Pentosyltransferase Peptidase Peroxidases Phagocyte NADPH oxidase Phosphoric diester hydrolase Phosphoric monoester hydrolase Phosphorus-oxygen lyase PP2C family Proton-dependent oligopeptide transporter Racemases and epimerase S-phase kinase-associated protein Serpin protein Short-chain dehydrogenases reductase Sirtuin family. Class I subfamily Sirtuin family. Class III subfamily Small GTPase Solute:sodium symporter Sphingomyelin synthase Sulfur donor oxidoreductase Sulfuric ester hydrolase Superoxide dismutase/reductase Toll-like receptor Topoisomerase Transaminase Transcription factor Transient receptor potential catioin channel Viral RNA helicase Voltage-gated ion channel Search Poor or Non Binders of Target by ICD-11 Defined Disease Class: Please select a disease class 1A00-1A09: Anaerobic bacterial infection 1A00-1C4Z: Bacterial infection 1A00-CA43: Postoperative inflammation 1A24-1D9Z: Virus infection 1A2Z: Viral intestinal infection 1A40: Infectious gastroenteritis/colitis 1A61-1A6Z: Syphilis 1A70-1A7Z: Gonococcal infection 1A95: Anogenital warts 1A9Y-1A9Z: Sexually transmitted infection 1B10-1B12: Tuberculosis 1B10-1B14: HIV-infected patients with tuberculosis 1B10-1B21: Mycobacterium infection 1B10-1F85: Pulmonary disease 1B40: Rheumatic fever 1B74-1F40: Gram-positive bacterial infection 1B92: Glanders 1C1G: Lyme borreliosis 1C60-1C62: Human immunodeficiency virus disease 1C80: Viral encephalitis 1D01: Infectious meningitis 1D0Y-1G2Z: Parasitic infection 1D0Y: CNS non-viral infection 1D2Z: Dengue fever 1D51-1F53: Trypanosomiasis 1D63: Henipavirus encephalitis 1D82: Cytomegaloviral disease 1D92: Coronavirus infection 1E30-1E32: Influenza 1E50-1E51: Hepatitis virus infection 1E76: Molluscum contagiosum 1E80: Common warts 1E91: Zoster 1F00: Herpes simplex infection 1F28-1G07: Itching 1F28-1G0Z: Skin and skin-structure infection 1F28: Dermatophytosis 1F29-1F2F: Fungal infection 1F40-1F45: Malaria 1F41-1G40: Gram-negative bacterial infection 1F51: African trypanosomiasis 1F54: Leishmaniasis 1F57: Toxoplasmosis 1F66: Filariasis 1F6A: Onchocerciasis 1F70-1F86: Flatworm infection 1F8Y: Trematode disease 1F90: Parasitic worm infestation 1G00: Pediculosis 1G40-1G41: Sepsis 1H0Z: Unspecific infection 2A00-2F9Z: Solid tumour/cancer 2A00: Brain cancer 2A01: Meningioma 2A02: Spinal cord/cranial nerve neoplasm 2A20: Myeloproliferative neoplasm 2A21: Mastocytosis 2A37: Myelodysplastic syndrome 2A40: Chronic myelomonocytic leukaemia 2A41: BCR-ABL1-negative chronic myeloid leukaemia 2A60-2B33: Leukaemia 2A60-2C35: Sarcoma 2A60: Acute myeloid leukaemia 2A80-2A86: Lymphoma 2A80: Follicular lymphoma 2A81: Diffuse large B-cell lymphoma 2A82: Mature B-cell leukaemia 2A83: Multiple myeloma 2A85: Mature B-cell lymphoma 2A86: B-cell lymphoma 2A90: Mature T-cell lymphoma 2B01: Mycosis fungoides 2B02: Sezary syndrome 2B30: Hodgkin lymphoma 2B32: Immunoproliferative disorder 2B33: Malignant haematopoietic neoplasm 2B51: Osteosarcoma 2B52: Ewing sarcoma 2B57: Kaposi sarcoma 2B59: Liposarcoma 2B5A: Synovial sarcoma 2B5B: Gastrointestinal stromal tumour 2B5D-2B5Y: Malignant mesenchymal neoplasm 2B5Z: Bone cancer 2B60-2D01: Squamous cell carcinoma 2B6B: Nasopharyngeal cancer 2B70: Esophageal cancer 2B71: Oesophagogastric junction cancer 2B72: Stomach cancer 2B90: Colon cancer 2B91: Colorectal cancer 2B92: Rectum cancer 2C00: Anal cancer 2C0Z: Malignant intestine neoplasm 2C10: Pancreatic cancer 2C11: Malignant digestive organ neoplasm 2C12: Liver cancer 2C14-2C17: Metastatic biliary tract neoplasms 2C17: Biliary tract cancer 2C25: Lung cancer 2C26: Pleural mesothelioma 2C27: Thymoma 2C30-2C37: Skin cancer 2C30: Melanoma 2C34: Neuroendocrine carcinoma 2C51: Peritoneal cancer 2C60-2C6Y: Breast cancer 2C60-2C6Z: Mammary tumour 2C72: Uterine ligament/parametrium/uterine adnexa neoplasm 2C73: Ovarian cancer 2C74: Fallopian tube cancer 2C76: Endometrial cancer 2C77: Cervical cancer 2C80: Testicular cancer 2C82: Prostate cancer 2C90: Renal cell carcinoma 2C92: Ureteral cancer 2C94: Bladder cancer 2C95-2C9Z: Urogenital cancer 2D00-2D07: Ocular cancer 2D02: Retina cancer 2D10: Thyroid cancer 2D11: Adrenal cancer 2D40: Adenocarcinoma 2D42: Head and neck cancer 2D50-2E09: Metastatic malignant neoplasm 2D50-2E2Z: Metastatic tumour 2D60: Metastatic lymph node neoplasm 2D70: Metastatic lung neoplasm 2E60: Oral cavity/oesophagus/stomach in situ carcinoma 2E65: Breast in situ carcinoma 2E81-2F2Y: Hemangioma 2E92: Digestive organ benign neoplasm 2F37: Endocrine gland neoplasm 2F7B: Bone/articular cartilage neoplasm 2F7C: Desmoid tumour 3A00-3A9Z: Anemia 3A20-3A2Z: Haemolytic anemia 3A20: Acquired haemolytic anaemia 3A51: Sickle-cell disorder 3A90: Acute disease anaemia 3B10: Coagulation defect 3B11: Christmas disease 3B14: Inherited coagulation factor deficiency 3B4Z: Clotting disorder 3B60: Non-thrombocytopenic purpura 3B62: Qualitative platelet defect 3B63: Thrombocytosis 3B64: Thrombocytopenia 3C0Z: Blood-forming organ disease 4A00-4A85: Immunodeficiency 4A00: Innate/adaptive immunodeficiency 4A01-4B41: Immune system disease 4A01: Adaptive immunity immunodeficiency 4A40-4A45: Autoimmune disease 4A40: Lupus erythematosus 4A41: Idiopathic inflammatory myopathy 4A42: Systemic sclerosis 4A43: Sjogren syndrome 4A44: Vasculitis 4A60: Monogenic autoinflammatory syndrome 4A80-4A8Z: Allergic/hypersensitivity disorder 4B00: Neutropenia 4B20: Sarcoidosis 4B24: Graft-versus-host disease 5A02: Thyrotoxicosis 5A10-5A11: Type-1/2 diabete 5A10: Diabetes mellitus 5A11: Type 2 diabetes mellitus 5A2Y: Acute diabete complication 5A41: Hypo-glycaemia 5A44: Insulin-resistance syndrome 5A4Y: Pancreatic internal secretion disorder 5A50: Hypo-parathyroidism 5A51: Hyper-parathyroidism 5A60-5A61: Pituitary gland disorder 5A61: Pituitary hypofunction 5A70: Cushing syndrome 5A71: Adrenogenital disorder 5A75: Adrenomedullary hyperfunction 5A80: Ovarian dysfunction 5A81: Testicular dysfunction 5B10: Carcinoid syndrome 5B50-5B71: Nutritional deficiency 5B55-5B5F: Vitamin deficiency 5B5K: Mineral deficiency 5B80-5B81: Obesity 5B91: Mineral excesses 5C50-5C59: Inborn metabolism deficiency 5C50-5D2Z: Metabolic disorder 5C50: Metabolism inborn error 5C51: Inborn carbohydrate metabolism error 5C52-5C59: Synthesis disorder 5C52: Inborn lipid metabolism error 5C53: Inborn energy metabolism error 5C55: Inborn purine/pyrimidine/nucleotide metabolism error 5C56: Lysosomal disease 5C57: Peroxisomal disease 5C58: Inborn porphyrin/heme metabolism error 5C59: Neurotransmitter metabolic error 5C64: Mineral absorption/transport disorder 5C72: Hypo-osmolality/hyponatraemia 5C73: Acidosis 5C80-5C81: Dyslipidemia 5C80: Hyper-lipoproteinaemia 5D00: Amyloidosis 6A02: Autism spectrum disorder 6A05: Attention deficit hyperactivity disorder 6A20-6A25: Psychotic disorder 6A20: Schizophrenia 6A21: Schizoaffective disorder 6A60-6E23: Mood disorder 6A60: Bipolar disorder 6A70-6A7Z: Depression 6B00-6B0Z: Anxiety disorder 6B04: Social anxiety disorder 6B25: Body-focused behaviour disorder 6B40-6B45: Stress 6B40: Post-traumatic stress disorder 6B60: Dissociative neurological symptom disorder 6B80: Anorexia nervosa 6B81: Bulimia nervosa 6B82: Binge eating disorder 6C00: Enuresis 6C40: Substance abuse 6C41: Cannabis use disorder 6C43: Opioid use disorder 6C45: Cocaine use disorder 6C4A: Nicotine use disorder 6C4G: Psychoactive substances use disorder 6C4Z: Unspecific substance use disorder 6C50-6C5Z: Addictive disorder 6C73: Intermittent explosive disorder 6D71: Mild neurocognitive disorder 6D80-6D8Z: Dementia 6D83: Frontotemporal dementia 6E20-6E8Z: Mental/behavioural/neurodevelopmental disorder 7A00-7A0Z: Insomnia 7A00-7B2Z: Sleep-wake disorder 7A00: Chronic insomnia 7A20: Narcolepsy 7A4Z: Sleep-related breathing disorder 7A60-7A65: Circadian rhythm sleep disorder 7A80: Restless legs syndrome 8A00-8A0Z: Neurobehavioral disorder 8A00: Parkinsonism 8A01: Choreiform disorder 8A02: Dystonic disorder 8A03: Ataxic disorder 8A04-8D87: Central nervous system disease 8A04-8E7Z: Central and peripheral nervous disease 8A05: Tic disorder 8A07-8A0Z: Movement disorder 8A20-8A23: Neurodegenerative disorder 8A20: Alzheimer disease 8A40: Multiple sclerosis 8A43: Neuromyelitis optica 8A61-8A6Z: Epilepsy/seizure 8A62: Epileptic encephalopathy 8A80-8A84: Headache 8A80: Migraine 8A81: Tension-type headache 8B10-8B11: Ischemia 8B11: Cerebral ischaemic stroke 8B1Z: Cerebral ischaemia 8B20: Ischaemic/haemorrhagic stroke 8B22-8B2Z: Cerebrovascular disease 8B60: Motor neuron disease 8B61: Muscular atrophy 8C01: Inflammatory polyneuropathy 8C0Z: Neuropathy 8C11: Lower limb mononeuropathy 8C60: Myasthenia gravis 8C6Y: Myasthenia gravis 8C70-8E61: Brain disease 8C70: Muscular dystrophy 8C71: Myotonic disorder 8D60: Increased intracranial pressure 8D64: Hydrocephalus 8D8A: Focal/segmental autonomic disorder 8E01: Acquired prion disease 8E02: Genetic prion disease 8E43: General pain disorder 8E47: Encephalopathy 9A01-9A0Z: Eye disorder 9A2Y-9C40: Atrophy 9A60: Conjunctiva disorder 9A61-9B7Y: Hyperaemia 9A76-9A78: Corneal disease 9A96: Anterior uveitis 9B10: Cataract 9B71: Retinopathy 9B72: Retinal inflammation 9B74: Retinal vascular occlusion 9B75: Macular degeneration 9C61: Glaucoma 9C82: Extraocular muscle disorder 9C84: Nystagmus 9E1Z: Visual system disease AA00-AA13: Otitis externa AA80-AB0Z: Otitis media AB31: Episodic vestibular syndrome BA00-BA04: Hypertension BA00-BE2Z: Cardiovascular disease BA00: Essential hypertension BA20-BA21: Hypotension BA21: Orthostatic hypotension BA40-BA6Z: Ischemic heart disease BA40: Angina pectoris BA41-BA42: Heart disease BA41-BA43: Myocardial infarction BA43: Coronary thrombosis BA6Z: Ischaemic heart disease BA80: Coronary atherosclerosis BA85: Coronary vasospastic disease BA86: Coronary microvascular disease BB00: Pulmonary thromboembolism BB01: Pulmonary hypertension BB40-BA42: Endocarditis BC45: Cardiomegaly BC63: Conduction disorder BC65: Genetic cardiac arrhythmia BC71: Ventricular tachyarrhythmia BC81: Supraventricular tachyarrhythmia BC9Z: Cardiac arrhythmia BD10-BD1Z: Heart failure BD11: Left ventricular failure BD40: Arterial occlusive disease BD42: Raynaud phenomenon BD4Z: Chronic arterial occlusive disease BD50: Aneurysm/dissection BD52: Arteries/arterioles disorder BD54: Diabetic foot ulcer BD71: Deep vein thrombosis BD72: Venous thromboembolism BD74: Chronic lower extremities peripheral venous insufficiency BD9Z: Lymphatic vessel/lymph nodes disorder BE2Z: Circulatory system disease CA00: Nasopharyngitis CA05: Acute laryngitis/tracheitis CA07-CA4Z: Respiratory infection CA07: Acute upper respiratory infection CA08: Vasomotor/allergic rhinitis CA0Z: Upper respiratory tract disorder CA21: Emphysema CA22: Chronic obstructive pulmonary disease CA23: Asthma CA24: Bronchiectasis CA25: Cystic fibrosis CA40: Pneumonia CB00: Acute respiratory distress syndrome CB03: Idiopathic interstitial pneumonitis CB07: Lymphangioleiomyomatosis CB40-CB7Z: Respiratory system disease DA08: Dental disease DA0C: Periodontal disease DA21: Oesophagus motility disorder DA22: Gastro-oesophageal reflux disease DA24: Oesophagitis DA25: Oesophageal ulcer DA2Y-DA2Z: Esophagus sensitivity DA41: Gastroduodenal motor/secretory disorder DA42-DA60: Chemotherapy/radiotherapy-induced mucositis DA42-DA63: Helicobacter infection DA42: Gastritis DA43-DA4Y: Stomach disease DA60: Gastric ulcer DA61: Peptic ulcer DA63: Duodenal ulcer DA91-DB30: Postoperative ileus DA95: Coeliac disease DB32: Large intestine motility disorder DB60: Haemorrhoids DB61-DD30: Arterial thrombosis DB61-GB90: Thrombosis DB90-DB9Z: Liver disease DB92: Non-alcoholic fatty liver disease DB93: Hepatic fibrosis/cirrhosis DB94: Alcoholic liver disease DB96: Autoimmune liver disease DB98: Liver vascular disorder DC11: Cholelithiasis DC30-DC3Z: Pancreatic malfunction DC31-DC34: Pancreatitis DC35-DC3Z: Pancreas disease DD70: Crohn disease DD71: Ulcerative colitis DD72: Indeterminate colitis DD90: Oesophageal/gastroduodenal disorder DD91: Irritable bowel syndrome DD93: Infants/toddlers/children functional digestive disorder DE2Z: Digestive system disease EA00-EM0Z: Skin disease EA60: Skin fungal infection disorder EA80-EA89: Eczema EA80: Atopic eczema EA81: Seborrhoeic dermatitis EA90: Psoriasis EA91: Lichen planus EB00-EB05: Urticaria EB00: Spontaneous urticaria EB21: Pyoderma gangrenosum EB40: Pemphigus EB41: Pemphigoid EB44: Dermatitis herpetiformis EB50-EB5Z: Cutaneous lupus erythematosus EC23: Skin pigmentation genetic disorder EC32: Dystrophic epidermolysis bullosa EC40: Pseudoxanthoma elasticum EC90: Pruritus EC91: Prurigo ED60: Acquired hypermelanosis ED61: Acquired melanotic macule/lentigine ED63: Acquired hypomelanotic disorder ED70: Alopecia ED80: Acne vulgaris ED90: Rosacea ED91: Sebaceous gland disorder ED92: Hidradenitis suppurativa EE00: Hyperhidrosis EE12: Nail/perionychium infection EE40: Dermal/subcutaneous connective tissue atrophy/degeneration EF20: Acquired cutaneous blood vessel malformation EK00-EK0Z: Contact dermatitis EK02: Irritant contact dermatitis EK20: Fragrance/cosmetics phototoxic reaction EK71: Skin tag/polyp EK90: Epidermal dysplasias FA00-FA05: Osteoarthritis FA00-FC0Z: Musculoskeletal disorder FA01: Knee osteoarthritis FA11: Reactive arthropathy FA20: Rheumatoid arthritis FA21: Psoriatic arthritis FA24: Juvenile idiopathic arthritis FA25: Gout FA2Z: Inflammatory arthropathy FA92: Inflammatory spondyloarthritis FB32-FB3Z: Muscle disorder FB56: Soft tissue disorder FB83: Low bone mass disorder FB85: Bone paget disease FC0Z: Musculoskeletal system/connective tissue disease GA02: Vaginitis GA0Z-GC8Z: Genitourinary disease GA10: Endometriosis GA12: Dyspareunia GA14-GC01: Fibrosis GA1Y: Female genital tract noninflammatory disorder GA20-GA21: Bleeding disorder GA20: Menstrual cycle bleeding disorder GA30: Menopausal disorder GA31: Female infertility GA34: Female pelvic pain GA90: Prostate hyperplasia GA91: Prostate disease GB04: Male infertility GB40: Nephritic syndrome GB60-GB6Z: Kidney failure GB61: Chronic kidney disease GC00: Cystitis GC01: Bladder disorder GC01: Kidney fibrosis GC08: Urinary tract infection GC2Z: Urinary system disease GC50: Functional bladder disorder HA00-HA01: Sexual dysfunction HA00: Hypoactive sexual desire dysfunction HA03: Ejaculatory dysfunction JA00: Abortion JA43: Postpartum haemorrhage JB00: Preterm labour/delivery JB42: Obstetric embolism JB46: Childbirth associated breast/lactation disorder JB63: Pregnancy/childbirth/puerperium maternal infection KB08: Newborn muscle tone disorder LA11: Eye anterior segment structural developmental anomaly LA90: Vascular system developmental anomaly LB20: Gallbladder/bile ducts/liver structural developmental anomaly LC30: Hair/hair growth developmental defect LD20: CNS anomalies syndrome LD24: Skeletal anomaly LD27: Skin/mucosal anomaly LD2A: Sex development malformative disorder LD2B: Premature ageing appearance LD2C: Overgrowth syndrome LD2D: Phakomatoses/hamartoneoplastic syndrome LD2F: Multiple structural anomalies syndrome LD55: Fragile X chromosome LD90: Intellectual development disorder MD12: Cough
