Target Validation Information
Target ID T93344
Target Name Squalene monooxygenase
Target Type
Successful
Drug Potency against Target Mallotinic acid Drug Info IC50 = 8000 nM [526128]
GERANIIN Drug Info IC50 = 4100 nM [526128]
1(beta)-O-galloylpedunculagin Drug Info IC50 = 7000 nM [526128]
ELLAGIC ACID Drug Info IC50 = 2000 nM [526128]
Trisnorsqualene alcohol Drug Info IC50 = 4000 nM [526128]
Procyanidin B-2 3,3'-di-O-gallate Drug Info IC50 = 540 nM [526128]
PEDUNCULAGIN Drug Info IC50 = 2000 nM [526128]
ETHYLGALLATE Drug Info IC50 = 4200 nM [526128]
1,2,3,4,6-penta-O-galloyl-beta-D-glucose Drug Info IC50 = 470 nM [526128]
THEASINENSIN A Drug Info IC50 = 130 nM [526128]
N-cetylgallate Drug Info IC50 = 590 nM [526128]
Chebulinic acid Drug Info IC50 = 12000 nM [526128]
FUROSIN Drug Info IC50 = 10000 nM [526128]
N-dodecylgallate Drug Info IC50 = 61 nM [526128]
EUGENIIN Drug Info IC50 = 1600 nM [526128]
EPIGALOCATECHIN GALLATE Drug Info IC50 = 690 nM [526128]
Trisnorsqualene cyclopropylamine Drug Info IC50 = 2000 nM [526128]
1,2,6-tri-O-galloyl-beta-D-glucose Drug Info IC50 = 630 nM [526128]
Trisnorsqualene difluoromethylidene Drug Info IC50 = 5400 nM [526128]
Sanguiin H-6 Drug Info IC50 = 12000 nM [526128]
CORILAGIN Drug Info IC50 = 4000 nM [526128]
Mallotusinic acid Drug Info IC50 = 8000 nM [526128]
OCTYL_GALLATE Drug Info IC50 = 830 nM [526128]
References
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
Ref 526128J Nat Prod. 2001 Aug;64(8):1010-4.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.

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