Target Validation Information
Target ID T02546
Target Name Sodium channel protein type 4 subunit alpha
Target Type
Clinical Trial
Drug Potency against Target 3-[4-(4-Fluoro-phenoxy)-phenyl]-1H-pyrazole Drug Info Ki = 200 nM [526983]
3-(4-Phenoxy-phenyl)-1H-pyrazole Drug Info Ki = 240 nM [526983]
V-102862 Drug Info Ki = 180 nM [526983]
References
Ref 526983J Med Chem. 2004 Mar 11;47(6):1547-52.3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
Ref 526983J Med Chem. 2004 Mar 11;47(6):1547-52.3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
Ref 526983J Med Chem. 2004 Mar 11;47(6):1547-52.3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.

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