| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T70490 | ||||
| Target Name | Dipeptidyl-peptidase I | ||||
| Target Type | Clinical Trial |
||||
| Drug Potency against Target | GNF-PF-5434 | Drug Info | IC50 = 4000 nM | [529350] | |
| (S)-2-amino-N-(1-cyano-2-phenylethyl)acetamide | Drug Info | IC50 = 4787 nM | [528170] | ||
| References | |||||
| Ref 529350 | Bioorg Med Chem. 2009 Feb 1;17(3):1064-70. Epub 2008 Feb 7.Substrate optimization for monitoring cathepsin C activity in live cells. | ||||
| Ref 528170 | Bioorg Med Chem Lett. 2006 Jul 1;16(13):3614-7. Epub 2006 May 2.Dipeptidyl nitriles as human dipeptidyl peptidase I inhibitors. | ||||
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