| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T79694 | ||||
| Target Name | Voltage-dependent T-type calcium channel alpha-1I subunit | ||||
| Target Type | Discontinued |
||||
| Drug Potency against Target | U-92032 | Drug Info | IC50 = 300 nM | [525864] | |
| References | |||||
| Ref 525864 | J Med Chem. 2000 Sep 7;43(18):3372-6.Discovery of (2S)-1-(4-amino-2,3,5- trimethylphenoxy)-3-[4-[4-(4- fluorobenzyl)phenyl]-1-piperazinyl]-2-propanol dimethanesulfonate (SUN N8075): a dual Na(+) and Ca(2+) channel blocker with antioxidant activity. | ||||
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