| Biomarker General Infomation |
| Biomarker ID |
BM001323 |
| Biomarker Name |
5-HT 2A receptor (HTR2A) |
| Disease |
Schizophrenia |
| ICD Code |
ICD-11: 6A20
|
| Biomarker Type |
Pharmacodynamic; theragnostic |
| Molecular Type |
Protein |
| Biomarker Location |
striatum; cortex |
| Biomarker Measure |
Occupancy |
| Specific Aim |
Target occupancy; help dose decision |
| Conclusion |
D2 or 5-HT2 receptor occupancy in striatum or cortex as measured using PET or SP ECT, currently considered the most reliable biomarker of target engagements for current antipsychotics. |
| Treatment |
antipsychotics |
| UniProt ID |
|
| References |
| REF 1 |
Biomarkers for antipsychotic therapies. Handb Exp Pharmacol. 2012;(212):339-60.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
