| Biomarker General Infomation |
| Biomarker ID |
BM003091 |
| Biomarker Name |
HLA-DR+-CD3+, CD4+, and CD8+ cells |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Increased |
| Conclusion |
HIV infection in both populations was associated with reduced IL-2, IL-4, IL-10, and IL-12 secretion, number of CD28+ and CD45RA+ CD8+ cells, and increased number of HLA-DR+-CD3+, CD4+, and CD8+ cells, and CD45RO+ CD8+ cells. |
| References |
| REF 1 |
Infection by different HIV-1 subtypes (B and C) results in a similar immune activation profile despite distinct immune backgrounds. J Acquir Immune Defic Syndr. 1999 Jun 1;21(2):157-63. J Acquir Immune Defic Syndr. 1999 Jun 1;21(2):157-63.
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