Biomarker General Infomation |
Biomarker ID |
BM003095 |
Biomarker Name |
CD57+ memory CD8+ T cells |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Higher |
Conclusion |
In both HIV infection and aging, immunosenescence is marked by an increased proportion of CD28-, CD57+ memory CD8+ T cells with reduced capacity to produce interleukin 2 (IL-2), increased production of IL-6, resistance to apoptosis, and shortened telomeres. |
References |
REF 1 |
Aging, inflammation, and HIV infection. Top Antivir Med. 2012 Aug-Sep;20(3):101-5. Top Antivir Med. 2012 Aug-Sep;20(3):101-5.
|