Biomarker General Infomation
Biomarker ID
BM003102
Biomarker Name
CD127(+) cells
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Reduced
Conclusion HIV infection was associated with a fall in the proportion of CD127(+) cells among memory CD8 lymphocytes that resulted in a higher CD127(-) CD45RA(-)CD27(+) CD8 T cell count in HIV-infected patients.
References
REF 1 CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients--reversal by highly active anti-retroviral therapy (... Clin Exp Immunol. 2006 Mar;143(3):398-403. Clin Exp Immunol. 2006 Mar;143(3):398-403.

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