Biomarker General Infomation |
Biomarker ID |
BM003102 |
Biomarker Name |
CD127(+) cells |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Reduced |
Conclusion |
HIV infection was associated with a fall in the proportion of CD127(+) cells among memory CD8 lymphocytes that resulted in a higher CD127(-) CD45RA(-)CD27(+) CD8 T cell count in HIV-infected patients. |
References |
REF 1 |
CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients--reversal by highly active anti-retroviral therapy (... Clin Exp Immunol. 2006 Mar;143(3):398-403. Clin Exp Immunol. 2006 Mar;143(3):398-403.
|
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