Biomarker General Infomation |
Biomarker ID |
BM003104 |
Biomarker Name |
BDCA-1(+) dendritic cells |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Lower |
Conclusion |
HIV infection of monocyte-derived DCs and circulating BDCA-1-positive DCs was significantly reduced upon the presence of virus-specific but non-neutralizing IgGs. |
References |
REF 1 |
IgG opsonization of HIV impedes provirus formation in and infection of dendritic cells and subsequent long-term transfer to T cells. J Immunol. 2007 Jun 15;178(12):7840-8. J Immunol. 2007 Jun 15;178(12):7840-8.
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