Biomarker General Infomation
Biomarker ID
BM003104
Biomarker Name
BDCA-1(+) dendritic cells
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Lower
Conclusion HIV infection of monocyte-derived DCs and circulating BDCA-1-positive DCs was significantly reduced upon the presence of virus-specific but non-neutralizing IgGs.
References
REF 1 IgG opsonization of HIV impedes provirus formation in and infection of dendritic cells and subsequent long-term transfer to T cells. J Immunol. 2007 Jun 15;178(12):7840-8. J Immunol. 2007 Jun 15;178(12):7840-8.

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